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The age of case-patients ranged from 11 to 14 years, 2 were boys, and none had preexisting conditions. All case-patients had fever and abdominal symptoms (abdominal pain, nausea, vomiting, or diarrhea) at admission. Mucocutaneous symptoms and signs (mucosal changes, skin rash, extremity changes) occurred in 2 patients, and all patients had documented hypotension (<50th percentile, adjusted for age, sex, and height). All case-patients had marked leukocytosis or elevated inflammatory markers. Echocardiography showed coronary artery dilatation (z-scores 1.64–3.98 mm for left coronary arteries), mitral regurgitation, or left ventricular dysfunction. Chest radiography or computed tomography showed pulmonary edema or pleural effusion. Abdominal ultrasound or computed tomography showed mesenteric lymphadenopathies, hyperechoic liver, or hypertrophic gall bladder. All 3 case-patients received intravenous immunoglobulin (IVIg); 1 patient (case 3) received methylprednisolone pulse therapy and immunomodulatory agent (Anakinra) because of persistent hypotension after initial IVIg treatment. Two patients received inotropic agents and required transfer to the intensive care unit (ICU), but no patients required mechanical ventilation. The duration of hospitalization was 10–19 days, and duration of ICU admission was 6–7 days. All 3 patients received aspirin and have survived to date with no major disease sequelae.	4.082031	0.850098	sec[0]/p[3]	en	0.999996	33539720	https://doi.org/10.3201/eid2704.210026	[ "patients", "abdominal", "changes", "hypotension", "coronary", "computed", "tomography", "ivig", "required", "duration" ]	[ { "code": "PL14.C", "title": "Patient received diagnostic test or treatment intended for another patient" }, { "code": "QB14", "title": "Unavailability or inaccessibility of health care facilities" }, { "code": "PL14.2", "title": "Problem associated with physical transfer of patient" }, { "code": "QB12.0", "title": "Organ transplant candidate" }, { "code": "QA15.1", "title": "Counselling related to sexual behaviour and orientation or sexual relationships of the person" }, { "code": "MD81.3", "title": "Acute abdomen" }, { "code": "JA01.0", "title": "Abdominal pregnancy" }, { "code": "ME04.Z", "title": "Ascites, unspecified" }, { "code": "NB51.0&XA3KX0", "title": "Laceration without foreign body of abdominal wall" }, { "code": "NB9Y", "title": "Other specified injuries to the abdomen, lower back, lumbar spine or pelvis" } ]	=== ICD-11 CODES FOUND === [PL14.C] Patient received diagnostic test or treatment intended for another patient Also known as: Patient received diagnostic test or treatment intended for another patient \| wrong patient \| incorrect patient Excludes: Procedure undertaken at wrong site or wrong side, as mode of injury or harm [QB14] Unavailability or inaccessibility of health care facilities Also known as: Unavailability or inaccessibility of health care facilities \| unavailability of medical facilities \| Unavailability of outpatient clinic \| Unavailability or inaccessibility of residential aged care service Excludes: bed unavailable [PL14.2] Problem associated with physical transfer of patient Also known as: Problem associated with physical transfer of patient [QB12.0] Organ transplant candidate Also known as: Organ transplant candidate \| patient waiting for organ availability \| health services provided because of need for organ transplant \| organ transplant candidate awaiting organ availability \| person on organ transplant waiting list [QA15.1] Counselling related to sexual behaviour and orientation or sexual relationships of the person Also known as: Counselling related to sexual behaviour and orientation or sexual relationships of the person \| advice on sexual behaviour or orientation \| counselling on sexual behaviour or orientation \| promiscuity counselling \| patient concerned regarding sexual orientation [MD81.3] Acute abdomen Definition: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases Also known as: Acute abdomen \| acute abdominal pain syndrome \| surgical abdomen \| abdominal acute syndrome \| severe abdomen pain [JA01.0] Abdominal pregnancy Definition: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy. Also known as: Abdominal pregnancy \| abdomen pregnancy \| intraperitoneal pregnancy Excludes: Maternal care for viable fetus in abdominal pregnancy \| Delivery of viable fetus in abdominal pregnancy [ME04.Z] Ascites, unspecified Also known as: Ascites, unspecified \| Ascites \| abdominal dropsy \| hydrops abdominis \| ascites NOS [NB9Y] Other specified injuries to the abdomen, lower back, lumbar spine or pelvis Also known as: Other specified injuries to the abdomen, lower back, lumbar spine or pelvis \| Abdominal wall trauma \| Injury of pelvic floor \| pelvic floor blunt injury \| pelvic floor blunt trauma === GRAPH WALKS === --- Walk 1 --- [PL14.C] Patient received diagnostic test or treatment intended for another patient --EXCLUDES--> [?] Procedure undertaken at wrong site or wrong side, as mode of injury or harm --CHILD--> [?] Performance of inappropriate operation --- Walk 2 --- [PL14.C] Patient received diagnostic test or treatment intended for another patient --EXCLUDES--> [?] Procedure undertaken at wrong site or wrong side, as mode of injury or harm --CHILD--> [?] Performance of inappropriate operation --- Walk 3 --- [QB14] Unavailability or inaccessibility of health care facilities --EXCLUDES--> [?] Person awaiting admission to adequate facility elsewhere --PARENT--> [?] Factors related to medical facilities or other health care --- Walk 4 --- [QB14] Unavailability or inaccessibility of health care facilities --EXCLUDES--> [?] Person awaiting admission to adequate facility elsewhere --CHILD--> [?] Person awaiting admission to mental health facility or unit --- Walk 5 --- [PL14.2] Problem associated with physical transfer of patient --PARENT--> [PL14] Mode of injury or harm associated with other health care related causes --EXCLUDES--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --- Walk 6 --- [PL14.2] Problem associated with physical transfer of patient --PARENT--> [PL14] Mode of injury or harm associated with other health care related causes --CHILD--> [PL14.2] Problem associated with physical transfer of patient	[ "[PL14.C] Patient received diagnostic test or treatment intended for another patient\n --EXCLUDES--> [?] Procedure undertaken at wrong site or wrong side, as mode of injury or harm\n --CHILD--> [?] Performance of inappropriate operation", "[PL14.C] Patient received diagnostic test or treatment intended for another patient\n --EXCLUDES--> [?] Procedure undertaken at wrong site or wrong side, as mode of injury or harm\n --CHILD--> [?] Performance of inappropriate operation", "[QB14] Unavailability or inaccessibility of health care facilities\n --EXCLUDES--> [?] Person awaiting admission to adequate facility elsewhere\n --PARENT--> [?] Factors related to medical facilities or other health care", "[QB14] Unavailability or inaccessibility of health care facilities\n --EXCLUDES--> [?] Person awaiting admission to adequate facility elsewhere\n --CHILD--> [?] Person awaiting admission to mental health facility or unit", "[PL14.2] Problem associated with physical transfer of patient\n --PARENT--> [PL14] Mode of injury or harm associated with other health care related causes\n --EXCLUDES--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance", "[PL14.2] Problem associated with physical transfer of patient\n --PARENT--> [PL14] Mode of injury or harm associated with other health care related causes\n --CHILD--> [PL14.2] Problem associated with physical transfer of patient" ]	PL14.C	Patient received diagnostic test or treatment intended for another patient	[ { "from_icd11": "QB14", "icd10_code": "Z753", "icd10_title": "Unavailability and inaccessibility of health-care facilities" }, { "from_icd11": "QA15.1", "icd10_code": "F66", "icd10_title": "Other sexual disorders" }, { "from_icd11": "QA15.1", "icd10_code": "F660", "icd10_title": "" }, { "from_icd11": "QA15.1", "icd10_code": "F661", "icd10_title": "" }, { "from_icd11": "QA15.1", "icd10_code": "F662", "icd10_title": "" }, { "from_icd11": "QA15.1", "icd10_code": "F668", "icd10_title": "" }, { "from_icd11": "QA15.1", "icd10_code": "F669", "icd10_title": "" }, { "from_icd11": "QA15.1", "icd10_code": "Z701", "icd10_title": "Counseling related to patient's sexual behavior and orientation" }, { "from_icd11": "MD81.3", "icd10_code": "R100", "icd10_title": "Acute abdomen" }, { "from_icd11": "JA01.0", "icd10_code": "O0000", "icd10_title": "Abdominal pregnancy without intrauterine pregnancy" }, { "from_icd11": "JA01.0", "icd10_code": "O000", "icd10_title": "Abdominal pregnancy" }, { "from_icd11": "ME04.Z", "icd10_code": "R180", "icd10_title": "Malignant ascites" }, { "from_icd11": "ME04.Z", "icd10_code": "R18", "icd10_title": "Ascites" } ]	Z753	Unavailability and inaccessibility of health-care facilities
To treat the symptomatic anemia, the patient was transfused with two units of crossmatch least incompatible warmed blood on day one and one unit of the same on day two of admission. The SARS-CoV-2 pneumonia was treated with oral remdesivir for five days and intravenous dexamethasone 6 mg for seven days. The patient was also given intravenous 40 mg furosemide for pulmonary congestion, and empiric ceftriaxone and azithromycin for pneumonia for three days. Post-transfusions, the patient’s day-three hemoglobin was 10.2 g/dL, which dropped in the next few days but stabilized at her baseline of 7-8 g/dL by discharge on day 10. By day three, the patient’s hyperkalemia had improved without intervention; the furosemide was discontinued since the patient was euvolemic on examination, and the azithromycin and ceftriaxone were stopped due to low concern for concomitant bacterial pneumonia. The patient remained in stable condition in the designated isolation room through the rest of her hospital stay, and after 10 days since her initial positive coronavirus 2019 (COVID-19) test, the isolation protocol was lifted. She reported feeling like she was “regaining her strength”. Yet, her oxygen levels persisted to desaturate with exertion and an ambulatory pulse oximetry examination revealed that she required 3 L of oxygen on discharge. The patient was recommended to be discharged to a sub-acute rehabilitation center.	3.578125	0.979492	sec[1]/p[3]	en	0.999997	34925989	https://doi.org/10.7759/cureus.19387	[ "pneumonia", "three", "intravenous", "furosemide", "ceftriaxone", "azithromycin", "since", "isolation", "oxygen", "treat" ]	[ { "code": "CA40.Z", "title": "Pneumonia, organism unspecified" }, { "code": "CA40.Y", "title": "Other specified pneumonia" }, { "code": "KB24", "title": "Congenital pneumonia" }, { "code": "CA40.1Z", "title": "Viral pneumonia, unspecified" }, { "code": "CA40.0Z", "title": "Bacterial pneumonia, unspecified" }, { "code": "1D45", "title": "Sandfly fever" }, { "code": "PA09", "title": "Unintentional land transport traffic event injuring an occupant of a low powered passenger vehicle" }, { "code": "LD50.Y", "title": "Other specified number anomalies of chromosome X" }, { "code": "PA19", "title": "Unintentional land transport nontraffic event injuring an occupant of a low powered passenger vehicle" }, { "code": "NA82.4", "title": "Multiple fractures of ribs" } ]	=== ICD-11 CODES FOUND === [CA40.Z] Pneumonia, organism unspecified Also known as: Pneumonia, organism unspecified \| Pneumonia \| infectious pneumonia \| PN - [pneumonia] \| lobar pneumonia NOS [CA40.Y] Other specified pneumonia Also known as: Other specified pneumonia \| Pneumonia in parasitic diseases \| Late acquired pneumonia \| Late-onset pneumonia due to other organisms \| Pleuropneumonia [KB24] Congenital pneumonia Definition: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi. Also known as: Congenital pneumonia \| acute congenital pneumonia \| congenital double pneumonia \| congenital purulent pneumonia \| congenital infective pneumonia Includes: infective pneumonia acquired in utero or during birth Excludes: Neonatal aspiration syndromes \| Pneumonitis [CA40.1Z] Viral pneumonia, unspecified Also known as: Viral pneumonia, unspecified \| Viral pneumonia \| acute viral pneumonia \| bronchopneumonia due to viruses other than influenza viruses \| interstitial viral pneumonia [CA40.0Z] Bacterial pneumonia, unspecified Also known as: Bacterial pneumonia, unspecified \| Bacterial pneumonia \| acute bacillus pneumonia \| acute bacterial pneumonia \| bacillus double pneumonia [1D45] Sandfly fever Also known as: Sandfly fever \| sandfly-borne phleboviral disease \| pappataci fever \| phlebotomus fever \| three day fever Includes: pappataci fever \| phlebotomus fever [PA09] Unintentional land transport traffic event injuring an occupant of a low powered passenger vehicle Also known as: Unintentional land transport traffic event injuring an occupant of a low powered passenger vehicle \| Occupant of three-wheeled motor vehicle injured in transport accident \| Occupant of three-wheeled motor vehicle injured in collision with pedestrian or animal \| Occupant of three-wheeled motor vehicle injured in collision with pedestrian or animal : person injured while boarding or alighting \| Occupant of three-wheeled motor vehicle injured in collision with pedestrian or animal : driver injured in traffic accident [LD50.Y] Other specified number anomalies of chromosome X Also known as: Other specified number anomalies of chromosome X \| Female with more than three X chromosomes \| abnormal female chromosomes, with more than three x chromosomes \| Tetrasomy X \| 48 xxxx syndrome [PA19] Unintentional land transport nontraffic event injuring an occupant of a low powered passenger vehicle Also known as: Unintentional land transport nontraffic event injuring an occupant of a low powered passenger vehicle \| Occupant of three-wheeled motor vehicle injured in nontraffic accident NOS \| Collision NOS involving three-wheeled motor vehicle, nontraffic \| Accident NOS involving three-wheeled motor vehicle, nontraffic \| Occupant of three-wheeled motor vehicle injured in collision with pedestrian or animal : driver injured in nontraffic accident [NA82.4] Multiple fractures of ribs Also known as: Multiple fractures of ribs \| rib fractures \| Multiple rib fractures, involving first rib \| Multiple rib fractures, involving two ribs \| Multiple rib fractures, involving three ribs === GRAPH WALKS === --- Walk 1 --- [CA40.Z] Pneumonia, organism unspecified --PARENT--> [CA40] Pneumonia Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ... --RELATED_TO--> [?] Congenital pneumonia Def: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi.... --- Walk 2 --- [CA40.Z] Pneumonia, organism unspecified --PARENT--> [CA40] Pneumonia Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ... --CHILD--> [CA40.0] Bacterial pneumonia Def: A disease of the pulmonary system, caused by an infection with a bacterial source. This disease is characterised by fever, lethargy, headache, myalgia, vomiting, or coughing. Transmission is by inhala... --- Walk 3 --- [CA40.Y] Other specified pneumonia --PARENT--> [CA40] Pneumonia Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ... --CHILD--> [CA40.0] Bacterial pneumonia Def: A disease of the pulmonary system, caused by an infection with a bacterial source. This disease is characterised by fever, lethargy, headache, myalgia, vomiting, or coughing. Transmission is by inhala... --- Walk 4 --- [CA40.Y] Other specified pneumonia --PARENT--> [CA40] Pneumonia Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ... --RELATED_TO--> [?] Congenital pneumonia Def: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi.... --- Walk 5 --- [KB24] Congenital pneumonia Def: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi.... --EXCLUDES--> [?] Neonatal aspiration syndromes Def: Aspiration of meconium, blood, amniotic fluids and gastric contents in a neonate resulting in clinical symptoms from airway obstruction (atelectasis, air trapping and air leaks), parenchymal injury (p... --CHILD--> [?] Neonatal aspiration of meconium Def: Meconium Aspiration Syndrome (MAS) is defined as respiratory distress in an infant born through meconium-stained amniotic fluid with roentgenographic findings consistent with MAS and whose symptoms co... --- Walk 6 --- [KB24] Congenital pneumonia Def: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi.... --PARENT--> [?] Respiratory disorders specific to the perinatal or neonatal period Def: A group of conditions occurring during the period of time around childbirth, especially the five months before and one month after birth which are associated with the cardiovascular or respiratory sys... --CHILD--> [KB20] Intrauterine hypoxia Def: Intrauterine hypoxia occurs when the fetus is deprived of an adequate supply of oxygen. This may occur with prolapse or occlusion of the umbilical cord, placental infarction and maternal smoking. This...	[ "[CA40.Z] Pneumonia, organism unspecified\n --PARENT--> [CA40] Pneumonia\n Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ...\n --RELATED_TO--> [?] Congenital pneumonia\n Def: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi....", "[CA40.Z] Pneumonia, organism unspecified\n --PARENT--> [CA40] Pneumonia\n Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ...\n --CHILD--> [CA40.0] Bacterial pneumonia\n Def: A disease of the pulmonary system, caused by an infection with a bacterial source. This disease is characterised by fever, lethargy, headache, myalgia, vomiting, or coughing. Transmission is by inhala...", "[CA40.Y] Other specified pneumonia\n --PARENT--> [CA40] Pneumonia\n Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ...\n --CHILD--> [CA40.0] Bacterial pneumonia\n Def: A disease of the pulmonary system, caused by an infection with a bacterial source. This disease is characterised by fever, lethargy, headache, myalgia, vomiting, or coughing. Transmission is by inhala...", "[CA40.Y] Other specified pneumonia\n --PARENT--> [CA40] Pneumonia\n Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ...\n --RELATED_TO--> [?] Congenital pneumonia\n Def: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi....", "[KB24] Congenital pneumonia\n Def: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi....\n --EXCLUDES--> [?] Neonatal aspiration syndromes\n Def: Aspiration of meconium, blood, amniotic fluids and gastric contents in a neonate resulting in clinical symptoms from airway obstruction (atelectasis, air trapping and air leaks), parenchymal injury (p...\n --CHILD--> [?] Neonatal aspiration of meconium\n Def: Meconium Aspiration Syndrome (MAS) is defined as respiratory distress in an infant born through meconium-stained amniotic fluid with roentgenographic findings consistent with MAS and whose symptoms co...", "[KB24] Congenital pneumonia\n Def: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi....\n --PARENT--> [?] Respiratory disorders specific to the perinatal or neonatal period\n Def: A group of conditions occurring during the period of time around childbirth, especially the five months before and one month after birth which are associated with the cardiovascular or respiratory sys...\n --CHILD--> [KB20] Intrauterine hypoxia\n Def: Intrauterine hypoxia occurs when the fetus is deprived of an adequate supply of oxygen. This may occur with prolapse or occlusion of the umbilical cord, placental infarction and maternal smoking. This..." ]	CA40.Z	Pneumonia, organism unspecified	[ { "from_icd11": "CA40.Z", "icd10_code": "J189", "icd10_title": "Pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J181", "icd10_title": "Lobar pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J188", "icd10_title": "Other pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J168", "icd10_title": "Pneumonia due to other specified infectious organisms" }, { "from_icd11": "CA40.Z", "icd10_code": "J180", "icd10_title": "Bronchopneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J17", "icd10_title": "Pneumonia in diseases classified elsewhere" }, { "from_icd11": "CA40.Z", "icd10_code": "J182", "icd10_title": "Hypostatic pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J16", "icd10_title": "Pneumonia due to other infectious organisms, not elsewhere classified" }, { "from_icd11": "CA40.Z", "icd10_code": "J171", "icd10_title": "" }, { "from_icd11": "CA40.Z", "icd10_code": "J173", "icd10_title": "" }, { "from_icd11": "CA40.Z", "icd10_code": "J178", "icd10_title": "" }, { "from_icd11": "CA40.Z", "icd10_code": "J18", "icd10_title": "Pneumonia, unspecified organism" }, { "from_icd11": "KB24", "icd10_code": "P23", "icd10_title": "Congenital pneumonia" }, { "from_icd11": "KB24", "icd10_code": "P230", "icd10_title": "Congenital pneumonia due to viral agent" }, { "from_icd11": "KB24", "icd10_code": "P231", "icd10_title": "Congenital pneumonia due to Chlamydia" } ]	J189	Pneumonia, unspecified organism
Lab workup included CK levels which were high as well as a high Aldolase ( 157 IU/L). Comprehensive metabolic panel (CMP) was remarkable for aspartate aminotransferase (AST) 284 IU/L, and alanine transaminase (ALT) 421 IU/L. The complete blood count (CBC) with differential was unremarkable. Lactic acid dehydrogenase (LDH) was also elevated with the value of 1415 IU/L. Urinalysis showed amber coloured urine, large blood, and mild proteinuria. Erythrocyte sedimentation rate (ESR), c-reactive protein (CRP), and thyroid-stimulating hormone (TSH) were within normal limits. The test for COVID PCR was negative. Antinuclear antibodies (ANA), anti-neutrophilic cytoplasmic autoantibody (ANCA) vasculitis profile, rheumatoid factor, anti-Jo-1, anti-scleroderma antibody, SSA and SSB antibody, hepatitis acute panel, extended myositis, and paraneoplastic reflexive panel were negative. His CK levels remained above 6000 for days despite aggressive hydration and discontinuation of statin . He had a muscle biopsy which revealed necrotizing myopathy . The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase antibody returned positive (>200 units) confirming the diagnosis of SINAM He was started on prednisone 40 mg which was tapered to 10 mg daily over two months. The patient was able to regain his baseline muscle strength with prednisone treatment alone in three months. Prednisone was then tapered over one month.	3.992188	0.973633	sec[1]/p[7]	en	0.999997	PMC8881230	https://doi.org/10.7759/cureus.21613	[ "which", "panel", "anti", "antibody", "prednisone", "blood", "muscle", "tapered", "over", "workup" ]	[ { "code": "BD50.41", "title": "Abdominal aortic aneurysm with rupture" }, { "code": "EK91", "title": "Dermatoses which may presage cutaneous lymphoma" }, { "code": "MH12.1", "title": "Death occurring less than 24 hours from onset of symptoms, not otherwise explained" }, { "code": "8A44.3", "title": "Certain specified leukodystrophies" }, { "code": "JA86.Y", "title": "Maternal care for other specified fetal problems" }, { "code": "MB23.1", "title": "Antisocial behaviour" }, { "code": "3B4Z", "title": "Coagulation defects, unspecified" }, { "code": "4A45.Z", "title": "Antiphospholipid syndrome, unspecified" }, { "code": "4A43.Y", "title": "Other specified overlap non-organ specific systemic autoimmune disease" }, { "code": "MA14.14", "title": "Anti-nuclear antibody positive" } ]	=== ICD-11 CODES FOUND === [BD50.41] Abdominal aortic aneurysm with rupture Also known as: Abdominal aortic aneurysm with rupture \| abdominal aorta aneurysm rupture \| abdominal aorta aneurysm ruptured \| abdominal aortic aneurysm which has ruptured \| ruptured AAA [EK91] Dermatoses which may presage cutaneous lymphoma Definition: Dermatoses which may represent the earliest stages of cutaneous lymphoma but where it is not possible to confirm their neoplastic nature. Also known as: Dermatoses which may presage cutaneous lymphoma [MH12.1] Death occurring less than 24 hours from onset of symptoms, not otherwise explained Also known as: Death occurring less than 24 hours from onset of symptoms, not otherwise explained \| died without sign of disease \| Death known not to be violent or instantaneous for which no cause can be discovered \| death known not to be violent or instantaneous, cause unknown \| Death without sign of disease Includes: Death known not to be violent or instantaneous for which no cause can be discovered \| Death without sign of disease [8A44.3] Certain specified leukodystrophies Also known as: Certain specified leukodystrophies \| CACH syndrome \| Vanishing white matter disease \| Childhood ataxia with central nervous system hypomyelination \| Congenital or early infantile CACH syndrome [JA86.Y] Maternal care for other specified fetal problems Also known as: Maternal care for other specified fetal problems \| Maternal care for other isoimmunization \| Isoimmunization NOS \| maternal antibodies NOS \| pregnancy management affected by incompatibility of blood groups NOS [MB23.1] Antisocial behaviour Definition: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated. Also known as: Antisocial behaviour \| Child or adolescent antisocial behaviour [3B4Z] Coagulation defects, unspecified Also known as: Coagulation defects, unspecified \| blood clotting disturbance \| blood clotting defect \| blood clotting factor deficiency \| clotting abnormality [4A45.Z] Antiphospholipid syndrome, unspecified Also known as: Antiphospholipid syndrome, unspecified \| Antiphospholipid syndrome \| Hughes syndrome \| Anticardiolipin syndrome [4A43.Y] Other specified overlap non-organ specific systemic autoimmune disease Also known as: Other specified overlap non-organ specific systemic autoimmune disease \| Antisynthetase syndrome \| Reynolds syndrome \| Syndromic multisystem autoimmune disease due to ITCH deficiency \| Eosinophilia myalgia syndrome [MA14.14] Anti-nuclear antibody positive Also known as: Anti-nuclear antibody positive \| ANA - [anti-nuclear antibody] positive === GRAPH WALKS === --- Walk 1 --- [BD50.41] Abdominal aortic aneurysm with rupture --PARENT--> [BD50.4] Abdominal aortic aneurysm --CHILD--> [BD50.40] Abdominal aortic aneurysm with perforation --- Walk 2 --- [BD50.41] Abdominal aortic aneurysm with rupture --PARENT--> [BD50.4] Abdominal aortic aneurysm --CHILD--> [BD50.40] Abdominal aortic aneurysm with perforation --- Walk 3 --- [EK91] Dermatoses which may presage cutaneous lymphoma Def: Dermatoses which may represent the earliest stages of cutaneous lymphoma but where it is not possible to confirm their neoplastic nature.... --CHILD--> [EK91.1] Poikiloderma vasculare atrophicans Def: Poikiloderma vasculare atrophicans is a cutaneous reaction pattern characterised by mottled hyper- and hypomelanosis, telangiectasia and progressive dermal and epidermal atrophy. It may manifest as a ... --PARENT--> [EK91] Dermatoses which may presage cutaneous lymphoma Def: Dermatoses which may represent the earliest stages of cutaneous lymphoma but where it is not possible to confirm their neoplastic nature.... --- Walk 4 --- [EK91] Dermatoses which may presage cutaneous lymphoma Def: Dermatoses which may represent the earliest stages of cutaneous lymphoma but where it is not possible to confirm their neoplastic nature.... --CHILD--> [EK91.0] Large plaque parapsoriasis Def: Large plaque parapsoriasis is a chronic skin disorder characterised by the indolent development over years or decades of scaly patches or slightly elevated plaques which may be clinically indistinguis... --PARENT--> [EK91] Dermatoses which may presage cutaneous lymphoma Def: Dermatoses which may represent the earliest stages of cutaneous lymphoma but where it is not possible to confirm their neoplastic nature.... --- Walk 5 --- [MH12.1] Death occurring less than 24 hours from onset of symptoms, not otherwise explained --PARENT--> [MH12] Other sudden death, cause unknown --EXCLUDES--> [?] Sudden infant death syndrome Def: Sudden infant death syndrome is the abrupt and unexplained death of an apparently healthy infant under one year of age, remaining unexplained after a thorough case investigation, including performance... --- Walk 6 --- [MH12.1] Death occurring less than 24 hours from onset of symptoms, not otherwise explained --PARENT--> [MH12] Other sudden death, cause unknown --CHILD--> [MH12.1] Death occurring less than 24 hours from onset of symptoms, not otherwise explained	[ "[BD50.41] Abdominal aortic aneurysm with rupture\n --PARENT--> [BD50.4] Abdominal aortic aneurysm\n --CHILD--> [BD50.40] Abdominal aortic aneurysm with perforation", "[BD50.41] Abdominal aortic aneurysm with rupture\n --PARENT--> [BD50.4] Abdominal aortic aneurysm\n --CHILD--> [BD50.40] Abdominal aortic aneurysm with perforation", "[EK91] Dermatoses which may presage cutaneous lymphoma\n Def: Dermatoses which may represent the earliest stages of cutaneous lymphoma but where it is not possible to confirm their neoplastic nature....\n --CHILD--> [EK91.1] Poikiloderma vasculare atrophicans\n Def: Poikiloderma vasculare atrophicans is a cutaneous reaction pattern characterised by mottled hyper- and hypomelanosis, telangiectasia and progressive dermal and epidermal atrophy. It may manifest as a ...\n --PARENT--> [EK91] Dermatoses which may presage cutaneous lymphoma\n Def: Dermatoses which may represent the earliest stages of cutaneous lymphoma but where it is not possible to confirm their neoplastic nature....", "[EK91] Dermatoses which may presage cutaneous lymphoma\n Def: Dermatoses which may represent the earliest stages of cutaneous lymphoma but where it is not possible to confirm their neoplastic nature....\n --CHILD--> [EK91.0] Large plaque parapsoriasis\n Def: Large plaque parapsoriasis is a chronic skin disorder characterised by the indolent development over years or decades of scaly patches or slightly elevated plaques which may be clinically indistinguis...\n --PARENT--> [EK91] Dermatoses which may presage cutaneous lymphoma\n Def: Dermatoses which may represent the earliest stages of cutaneous lymphoma but where it is not possible to confirm their neoplastic nature....", "[MH12.1] Death occurring less than 24 hours from onset of symptoms, not otherwise explained\n --PARENT--> [MH12] Other sudden death, cause unknown\n --EXCLUDES--> [?] Sudden infant death syndrome\n Def: Sudden infant death syndrome is the abrupt and unexplained death of an apparently healthy infant under one year of age, remaining unexplained after a thorough case investigation, including performance...", "[MH12.1] Death occurring less than 24 hours from onset of symptoms, not otherwise explained\n --PARENT--> [MH12] Other sudden death, cause unknown\n --CHILD--> [MH12.1] Death occurring less than 24 hours from onset of symptoms, not otherwise explained" ]	BD50.41	Abdominal aortic aneurysm with rupture	[ { "from_icd11": "BD50.41", "icd10_code": "I713", "icd10_title": "Abdominal aortic aneurysm, ruptured" }, { "from_icd11": "EK91", "icd10_code": "L989", "icd10_title": "Disorder of the skin and subcutaneous tissue, unspecified" }, { "from_icd11": "MH12.1", "icd10_code": "R961", "icd10_title": "" }, { "from_icd11": "JA86.Y", "icd10_code": "O26841 ", "icd10_title": "" }, { "from_icd11": "JA86.Y", "icd10_code": "O26843 ", "icd10_title": "" }, { "from_icd11": "JA86.Y", "icd10_code": "O26849 ", "icd10_title": "" }, { "from_icd11": "JA86.Y", "icd10_code": "O3680X0 ", "icd10_title": "" }, { "from_icd11": "3B4Z", "icd10_code": "D688", "icd10_title": "Other specified coagulation defects" }, { "from_icd11": "3B4Z", "icd10_code": "D689", "icd10_title": "Coagulation defect, unspecified" }, { "from_icd11": "3B4Z", "icd10_code": "D699", "icd10_title": "Hemorrhagic condition, unspecified" }, { "from_icd11": "3B4Z", "icd10_code": "D698", "icd10_title": "Other specified hemorrhagic conditions" }, { "from_icd11": "3B4Z", "icd10_code": "D65-D69", "icd10_title": "" }, { "from_icd11": "3B4Z", "icd10_code": "D69", "icd10_title": "Purpura and other hemorrhagic conditions" }, { "from_icd11": "4A45.Z", "icd10_code": "D6861", "icd10_title": "Antiphospholipid syndrome" }, { "from_icd11": "4A45.Z", "icd10_code": "D6869", "icd10_title": "Other thrombophilia" } ]	I713	Abdominal aortic aneurysm, ruptured
A 31-year-old man with a past medical history of IV heroin use, presented to the ED by EMS for CNS and respiratory depression after IV heroin use. The patient’s girlfriend provided the history that the patient was using a new type of heroin called “Santa Muerte.” The patient was given a total of four mg IN naloxone in the field, after which he became agitated, combative, and tachycardic. His vital signs on arrival included a HR of 163 beats per minute, BP of 131/81 mmHg, RR of 29 breaths per minute, SpO2 99% on room air, and oral temperature 98.8 degrees F. While in the ED, he continued to be agitated and combative. On examination, he was tachycardic and flushed with dilated pupils and a palpable full bladder in the suprapubic region. The patient was given a total of 10 mg of lorazepam with minimal improvement of his agitation, and he was later intubated for airway protection. Complete blood count (CBC) and basic metabolic panel (BMP) were unremarkable, and urine drug screening immunoassay was positive for opiates. Serum comprehensive drug screen by LC-MS-MS was positive for heroin, 6-MAM, fentanyl, and negative for any SCs. The patient later developed ARDS, requiring increased ventilator setting and was transferred to a tertiary center for VV-ECMO. Specialty laboratory testing of the patient’s confiscated drug by GC-MS and LCQ-TOF was positive for the novel SC 5F-MDMB-PINACA, heroin, and fentanyl.	3.806641	0.981445	sec[1]/sec[2]/p[0]	en	0.999998	32426651	https://doi.org/10.5811/cpcem.2020.2.45060	[ "heroin", "drug", "total", "agitated", "combative", "tachycardic", "minute", "fentanyl", "past", "respiratory" ]	[ { "code": "6C43.2Z", "title": "Opioid dependence, unspecified" }, { "code": "PB20&XM05B3", "title": "Accidental heroin poisoning" }, { "code": "6C43.3", "title": "Opioid intoxication" }, { "code": "6C43.4", "title": "Opioid withdrawal" }, { "code": "6C43.Y", "title": "Other specified disorders due to use of opioids" }, { "code": "QE11.Z", "title": "Hazardous drug use, unspecified" }, { "code": "6C4G.2Z", "title": "Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecified" }, { "code": "NE60", "title": "Harmful effects of drugs, medicaments or biological substances, not elsewhere classified" }, { "code": "4A85.0Z", "title": "Drug hypersensitivity of unspecified type" }, { "code": "6C4G.3", "title": "Intoxication due to unknown or unspecified psychoactive substance" } ]	=== ICD-11 CODES FOUND === [6C43.2Z] Opioid dependence, unspecified Also known as: Opioid dependence, unspecified \| Opioid dependence \| opioid addiction \| opiate dependence \| opium dependence [6C43.3] Opioid intoxication Definition: Opioid intoxication is a clinically significant transient condition that develops during or shortly after the consumption of opioids that is characterised by disturbances in consciousness, cognition, perception, affect, behaviour, or coordination. These disturbances are caused by the known pharmacological effects of opioids and their intensity is closely related to the amount of opioids consumed. They are time-limited and abate as opioids are cleared from the body. Presenting features may includ Also known as: Opioid intoxication \| heroin intoxication \| bad trip due to opioids \| Acute intoxication due to fentanyl \| Fentanyl and despropionyl fentanyl intoxication Excludes: opioid poisoning \| Possession trance disorder \| fentanyl poisoning [6C43.4] Opioid withdrawal Definition: Opioid withdrawal is a clinically significant cluster of symptoms, behaviours and/or physiological features, varying in degree of severity and duration, that occurs upon cessation or reduction of use of opioids in individuals who have developed Opioid dependence or have used opioids for a prolonged period or in large amounts. Opioid withdrawal can also occur when prescribed opioids have been used in standard therapeutic doses. Presenting features of Opioid withdrawal may include dysphoric mood, Also known as: Opioid withdrawal \| Opioid withdrawal, uncomplicated \| Opioid withdrawal, with seizures \| Codeine withdrawal \| Heroin withdrawal [6C43.Y] Other specified disorders due to use of opioids Also known as: Other specified disorders due to use of opioids \| Disorders due to use of codeine \| Disorders due to abuse of codeine \| Disorders due to use of heroin \| Disorders due to abuse of heroin [QE11.Z] Hazardous drug use, unspecified Also known as: Hazardous drug use, unspecified \| Hazardous drug use \| chronic drug use NOS \| chronic IV substance use \| drug use nos [6C4G.2Z] Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecified Also known as: Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecified \| Unknown or unspecified psychoactive substance dependence \| Drug dependence NOS [NE60] Harmful effects of drugs, medicaments or biological substances, not elsewhere classified Also known as: Harmful effects of drugs, medicaments or biological substances, not elsewhere classified \| drugs, medicaments or biological substances, toxicity not elsewhere classified \| adverse drug effects \| drug reaction NOS \| drug allergy NOS Excludes: Alcohol intoxication \| pathological drug intoxication \| hypersensitivity reaction to correctly administered drug [4A85.0Z] Drug hypersensitivity of unspecified type Also known as: Drug hypersensitivity of unspecified type \| Drug or pharmacological agents hypersensitivity \| medicinal hypersensitivity \| drug sensitivity NOS [6C4G.3] Intoxication due to unknown or unspecified psychoactive substance Definition: Intoxication due to unknown or unspecified psychoactive substance is a transient condition that develops during or shortly after the administration of an unknown or unspecified psychoactive substance that is characterised by disturbances in level of consciousness, cognition, perception, affect or behaviour, or other psychophysiological functions and responses. This diagnosis should be made only when there is strong evidence that an unidentified substance has been taken and the features cannot be Also known as: Intoxication due to unknown or unspecified psychoactive substance \| psychoactive substance abuse \| trance and possession disorders in psychoactive substance intoxication \| drug intoxication NOS === GRAPH WALKS === --- Walk 1 --- [6C43.2Z] Opioid dependence, unspecified --PARENT--> [6C43.2] Opioid dependence Def: Opioid dependence is a disorder of regulation of opioid use arising from repeated or continuous use of opioids. The characteristic feature is a strong internal drive to use opioids, which is manifeste... --EXCLUDES--> [?] Harmful pattern of use of opioids Def: A pattern of use of opioids that has caused damage to a person’s physical or mental health or has resulted in behaviour leading to harm to the health of others. The pattern of opioid use is evident ov... --- Walk 2 --- [6C43.2Z] Opioid dependence, unspecified --PARENT--> [6C43.2] Opioid dependence Def: Opioid dependence is a disorder of regulation of opioid use arising from repeated or continuous use of opioids. The characteristic feature is a strong internal drive to use opioids, which is manifeste... --CHILD--> [6C43.22] Opioid dependence, sustained partial remission Def: After a diagnosis of Opioid dependence, and often following a treatment episode or other intervention (including self-help intervention), there is a significant reduction in opioid consumption for mor... --- Walk 3 --- [6C43.3] Opioid intoxication Def: Opioid intoxication is a clinically significant transient condition that develops during or shortly after the consumption of opioids that is characterised by disturbances in consciousness, cognition, ... --EXCLUDES--> [?] Harmful effects of opioids or related analgesics --CHILD--> [?] Harmful effects of oxycodone --- Walk 4 --- [6C43.3] Opioid intoxication Def: Opioid intoxication is a clinically significant transient condition that develops during or shortly after the consumption of opioids that is characterised by disturbances in consciousness, cognition, ... --EXCLUDES--> [?] Harmful effects of opioids or related analgesics --CHILD--> [?] Harmful effects of opium --- Walk 5 --- [6C43.4] Opioid withdrawal Def: Opioid withdrawal is a clinically significant cluster of symptoms, behaviours and/or physiological features, varying in degree of severity and duration, that occurs upon cessation or reduction of use ... --PARENT--> [6C43] Disorders due to use of opioids Def: Disorders due to use of opioids are characterised by the pattern and consequences of opioid use. Opioids is a generic term that encompasses the constituents or derivatives of the opium poppy Papaver s... --EXCLUDES--> [?] Hazardous use of opioids Def: A pattern of opioid use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health profe... --- Walk 6 --- [6C43.4] Opioid withdrawal Def: Opioid withdrawal is a clinically significant cluster of symptoms, behaviours and/or physiological features, varying in degree of severity and duration, that occurs upon cessation or reduction of use ... --PARENT--> [6C43] Disorders due to use of opioids Def: Disorders due to use of opioids are characterised by the pattern and consequences of opioid use. Opioids is a generic term that encompasses the constituents or derivatives of the opium poppy Papaver s... --EXCLUDES--> [?] Hazardous use of opioids Def: A pattern of opioid use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health profe...	[ "[6C43.2Z] Opioid dependence, unspecified\n --PARENT--> [6C43.2] Opioid dependence\n Def: Opioid dependence is a disorder of regulation of opioid use arising from repeated or continuous use of opioids. The characteristic feature is a strong internal drive to use opioids, which is manifeste...\n --EXCLUDES--> [?] Harmful pattern of use of opioids\n Def: A pattern of use of opioids that has caused damage to a person’s physical or mental health or has resulted in behaviour leading to harm to the health of others. The pattern of opioid use is evident ov...", "[6C43.2Z] Opioid dependence, unspecified\n --PARENT--> [6C43.2] Opioid dependence\n Def: Opioid dependence is a disorder of regulation of opioid use arising from repeated or continuous use of opioids. The characteristic feature is a strong internal drive to use opioids, which is manifeste...\n --CHILD--> [6C43.22] Opioid dependence, sustained partial remission\n Def: After a diagnosis of Opioid dependence, and often following a treatment episode or other intervention (including self-help intervention), there is a significant reduction in opioid consumption for mor...", "[6C43.3] Opioid intoxication\n Def: Opioid intoxication is a clinically significant transient condition that develops during or shortly after the consumption of opioids that is characterised by disturbances in consciousness, cognition, ...\n --EXCLUDES--> [?] Harmful effects of opioids or related analgesics\n --CHILD--> [?] Harmful effects of oxycodone", "[6C43.3] Opioid intoxication\n Def: Opioid intoxication is a clinically significant transient condition that develops during or shortly after the consumption of opioids that is characterised by disturbances in consciousness, cognition, ...\n --EXCLUDES--> [?] Harmful effects of opioids or related analgesics\n --CHILD--> [?] Harmful effects of opium", "[6C43.4] Opioid withdrawal\n Def: Opioid withdrawal is a clinically significant cluster of symptoms, behaviours and/or physiological features, varying in degree of severity and duration, that occurs upon cessation or reduction of use ...\n --PARENT--> [6C43] Disorders due to use of opioids\n Def: Disorders due to use of opioids are characterised by the pattern and consequences of opioid use. Opioids is a generic term that encompasses the constituents or derivatives of the opium poppy Papaver s...\n --EXCLUDES--> [?] Hazardous use of opioids\n Def: A pattern of opioid use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health profe...", "[6C43.4] Opioid withdrawal\n Def: Opioid withdrawal is a clinically significant cluster of symptoms, behaviours and/or physiological features, varying in degree of severity and duration, that occurs upon cessation or reduction of use ...\n --PARENT--> [6C43] Disorders due to use of opioids\n Def: Disorders due to use of opioids are characterised by the pattern and consequences of opioid use. Opioids is a generic term that encompasses the constituents or derivatives of the opium poppy Papaver s...\n --EXCLUDES--> [?] Hazardous use of opioids\n Def: A pattern of opioid use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health profe..." ]	6C43.2Z	Opioid dependence, unspecified	[ { "from_icd11": "6C43.2Z", "icd10_code": "F1120", "icd10_title": "Opioid dependence, uncomplicated" }, { "from_icd11": "6C43.2Z", "icd10_code": "F1123", "icd10_title": "Opioid dependence with withdrawal" }, { "from_icd11": "6C43.2Z", "icd10_code": "F11221", "icd10_title": "Opioid dependence with intoxication delirium" }, { "from_icd11": "6C43.2Z", "icd10_code": "F1121", "icd10_title": "Opioid dependence, in remission" }, { "from_icd11": "6C43.2Z", "icd10_code": "F11229", "icd10_title": "Opioid dependence with intoxication, unspecified" }, { "from_icd11": "6C43.2Z", "icd10_code": "F11288", "icd10_title": "Opioid dependence with other opioid-induced disorder" }, { "from_icd11": "6C43.2Z", "icd10_code": "F1129", "icd10_title": "Opioid dependence with unspecified opioid-induced disorder" }, { "from_icd11": "6C43.2Z", "icd10_code": "F11220", "icd10_title": "Opioid dependence with intoxication, uncomplicated" }, { "from_icd11": "6C43.2Z", "icd10_code": "F1124", "icd10_title": "Opioid dependence with opioid-induced mood disorder" }, { "from_icd11": "6C43.2Z", "icd10_code": "F11250", "icd10_title": "Opioid dependence with opioid-induced psychotic disorder with delusions" }, { "from_icd11": "6C43.2Z", "icd10_code": "F11222", "icd10_title": "Opioid dependence with intoxication with perceptual disturbance" }, { "from_icd11": "6C43.2Z", "icd10_code": "F11259", "icd10_title": "Opioid dependence with opioid-induced psychotic disorder, unspecified" }, { "from_icd11": "6C43.2Z", "icd10_code": "F11281", "icd10_title": "Opioid dependence with opioid-induced sexual dysfunction" }, { "from_icd11": "6C43.2Z", "icd10_code": "F11282", "icd10_title": "Opioid dependence with opioid-induced sleep disorder" }, { "from_icd11": "6C43.2Z", "icd10_code": "F112", "icd10_title": "Opioid dependence" } ]	F1120	Opioid dependence, uncomplicated
In usual vHIT testing of patients with vestibular hypofunction and reduced eye velocity during the head impulse, the corrective saccade is called compensatory since it returns the gaze to the target by canceling out the gaze position error caused by the inadequate eye velocity. In the case of enhanced eye velocity, a corrective saccade is also necessary to return gaze to the fixation target. Therefore, this corrective saccade is also compensatory in the sense that it cancels the gaze position error caused by the enhanced eye velocity. Although this saccade is compensatory, it is in the opposite direction to the common compensatory saccade recorded in patients with vestibular hypofunction. To avoid confusion we have used the term “backup saccade” to refer to this corrective saccade after enhanced eye velocity. Until now, when enhanced vestibular slow phase eye velocity during head impulses have been observed on vHIT testing, no corrective backup saccades have been described ( 3 ). In this case report we describe, for what we think is the first time, a patient with definite MD with enhanced eye velocity (and so enhanced VOR gain) during head impulse testing, who showed compensatory saccades (“backup saccades”). These backup saccades were observed on clinical HIT tests, recorded on head impulse testing using vHIT and further confirmed by their occurrence during visual-vestibular reflex (VVOR) testing.	4.273438	0.873535	sec[0]/p[1]	en	0.999997	34957197	https://doi.org/10.3389/fsurg.2021.727672	[ "velocity", "saccade", "enhanced", "testing", "corrective", "compensatory", "vestibular", "head", "gaze", "this" ]	[ { "code": "9C85.00", "title": "Disorders of the saccadic pulse" }, { "code": "9C85.02", "title": "Inappropriate saccades" }, { "code": "9C85.01", "title": "Disorders of the saccadic step" }, { "code": "9C85.0Z", "title": "Anomalies of saccadic eye movements, unspecified" }, { "code": "9C82.4", "title": "Oculomotor apraxia" }, { "code": "8A04.0", "title": "Enhanced physiological tremor" }, { "code": "8E4A.0", "title": "Paraneoplastic or autoimmune disorders of the central nervous system, brain or spinal cord" }, { "code": "QA40", "title": "Pregnancy examination or test" }, { "code": "QA00.6Z", "title": "Examination of eyes or vision, unspecified" }, { "code": "QA00.7", "title": "Examination of ears and hearing" } ]	=== ICD-11 CODES FOUND === [9C85.00] Disorders of the saccadic pulse Also known as: Disorders of the saccadic pulse \| Disorders of saccadic velocity \| Slow saccades \| Disorders of saccadic accuracy \| Saccadic (pulse) dysmetria [9C85.02] Inappropriate saccades Also known as: Inappropriate saccades \| Saccadic intrusions and oscillations \| Square-wave jerks, 0.1-0.4 degrees \| Macrosquare-wave jerks \| Square-wave pulses, >0.5 degrees Includes: Saccadic intrusions and oscillations [9C85.01] Disorders of the saccadic step Also known as: Disorders of the saccadic step [9C85.0Z] Anomalies of saccadic eye movements, unspecified Also known as: Anomalies of saccadic eye movements, unspecified \| Anomalies of saccadic eye movements [9C82.4] Oculomotor apraxia Also known as: Oculomotor apraxia \| Congenital ocular motor apraxia \| Cogan’s congenital ocular motor apraxia \| Saccadic palsy \| Head thrust movement [8A04.0] Enhanced physiological tremor Definition: This is a high frequency, low amplitude tremor present with posture or action. It represents an exacerbation of a physiologic tremor which may have been worsened by drugs, stress, anxiety, etc. Also known as: Enhanced physiological tremor [8E4A.0] Paraneoplastic or autoimmune disorders of the central nervous system, brain or spinal cord Definition: Paraneoplastic and autoimmune disorders of the central nervous system, brain and spinal cord nervous system result from a targeted immune attack on neurons or glial cells in the central (e.g. encephalopathy, ataxia, myelopathy, myelitis) nervous system. In the paraneoplastic context, this attack is a consequence of a potentially effective tumour immune response initiated by onco-neural antigens derived from a systemic cancer. In the non-paraneoplastic context termed ‘autoimmune’ the etiology rem Also known as: Paraneoplastic or autoimmune disorders of the central nervous system, brain or spinal cord \| Paraneoplastic encephalitis \| Paraneoplastic encephalitis, neural autoantibody positive \| Paraneoplastic encephalitis, neural autoantibody negative \| Autoimmune encephalitis [QA40] Pregnancy examination or test Also known as: Pregnancy examination or test \| pregnancy examination \| pregnancy test \| Pregnancy examination or test, pregnancy not confirmed \| pregnancy not yet confirmed [QA00.6Z] Examination of eyes or vision, unspecified Also known as: Examination of eyes or vision, unspecified \| Examination of eyes or vision \| general eye examination \| routine eye examination \| vision examination [QA00.7] Examination of ears and hearing Also known as: Examination of ears and hearing \| examination of ear \| hearing examination \| hearing test === GRAPH WALKS === --- Walk 1 --- [9C85.00] Disorders of the saccadic pulse --PARENT--> [9C85.0] Anomalies of saccadic eye movements --CHILD--> [9C85.01] Disorders of the saccadic step --- Walk 2 --- [9C85.00] Disorders of the saccadic pulse --PARENT--> [9C85.0] Anomalies of saccadic eye movements --CHILD--> [9C85.02] Inappropriate saccades --- Walk 3 --- [9C85.02] Inappropriate saccades --PARENT--> [9C85.0] Anomalies of saccadic eye movements --CHILD--> [9C85.00] Disorders of the saccadic pulse --- Walk 4 --- [9C85.02] Inappropriate saccades --PARENT--> [9C85.0] Anomalies of saccadic eye movements --CHILD--> [9C85.00] Disorders of the saccadic pulse --- Walk 5 --- [9C85.01] Disorders of the saccadic step --PARENT--> [9C85.0] Anomalies of saccadic eye movements --CHILD--> [9C85.00] Disorders of the saccadic pulse --- Walk 6 --- [9C85.01] Disorders of the saccadic step --PARENT--> [9C85.0] Anomalies of saccadic eye movements --CHILD--> [9C85.01] Disorders of the saccadic step	[ "[9C85.00] Disorders of the saccadic pulse\n --PARENT--> [9C85.0] Anomalies of saccadic eye movements\n --CHILD--> [9C85.01] Disorders of the saccadic step", "[9C85.00] Disorders of the saccadic pulse\n --PARENT--> [9C85.0] Anomalies of saccadic eye movements\n --CHILD--> [9C85.02] Inappropriate saccades", "[9C85.02] Inappropriate saccades\n --PARENT--> [9C85.0] Anomalies of saccadic eye movements\n --CHILD--> [9C85.00] Disorders of the saccadic pulse", "[9C85.02] Inappropriate saccades\n --PARENT--> [9C85.0] Anomalies of saccadic eye movements\n --CHILD--> [9C85.00] Disorders of the saccadic pulse", "[9C85.01] Disorders of the saccadic step\n --PARENT--> [9C85.0] Anomalies of saccadic eye movements\n --CHILD--> [9C85.00] Disorders of the saccadic pulse", "[9C85.01] Disorders of the saccadic step\n --PARENT--> [9C85.0] Anomalies of saccadic eye movements\n --CHILD--> [9C85.01] Disorders of the saccadic step" ]	9C85.00	Disorders of the saccadic pulse	[ { "from_icd11": "9C85.00", "icd10_code": "H49-H52", "icd10_title": "" }, { "from_icd11": "9C82.4", "icd10_code": "H518", "icd10_title": "Other specified disorders of binocular movement" }, { "from_icd11": "8A04.0", "icd10_code": "G252", "icd10_title": "Other specified forms of tremor" }, { "from_icd11": "8E4A.0", "icd10_code": "G3183", "icd10_title": "Dementia with Lewy bodies" }, { "from_icd11": "8E4A.0", "icd10_code": "G2581", "icd10_title": "Restless legs syndrome" }, { "from_icd11": "8E4A.0", "icd10_code": "G3184", "icd10_title": "Mild cognitive impairment, so stated" }, { "from_icd11": "8E4A.0", "icd10_code": "G9349", "icd10_title": "Other encephalopathy" }, { "from_icd11": "8E4A.0", "icd10_code": "G0481", "icd10_title": "Other encephalitis and encephalomyelitis" }, { "from_icd11": "8E4A.0", "icd10_code": "G9589", "icd10_title": "Other specified diseases of spinal cord" }, { "from_icd11": "8E4A.0", "icd10_code": "G2589", "icd10_title": "Other specified extrapyramidal and movement disorders" }, { "from_icd11": "8E4A.0", "icd10_code": "G3189", "icd10_title": "Other specified degenerative diseases of nervous system" }, { "from_icd11": "8E4A.0", "icd10_code": "G2582", "icd10_title": "Stiff-man syndrome" }, { "from_icd11": "8E4A.0", "icd10_code": "G0489", "icd10_title": "Other myelitis" }, { "from_icd11": "8E4A.0", "icd10_code": "G9581", "icd10_title": "Conus medullaris syndrome" }, { "from_icd11": "8E4A.0", "icd10_code": "G3185", "icd10_title": "Corticobasal degeneration" } ]	H49-H52
A 73-year-old man was admitted to the hospital for cough lasting half a year. The CT examination revealed a neoplasm in the right lung, and biopsy pathology confirmed squamous cell carcinoma. The patient had smoked for a long time, had poor lung function, and refused surgery and SBRT. Image-guided microwave ablation of the lung cancer was performed with a power of 40 W and an ablation time of 8 min. The CT examination 1 week after ablation revealed no significant pneumothorax or pleural effusion. At the follow-up after discharge, CT showed no recurrence at the 10th month. We reconstructed the pre- and postablation CT to find that the ablation zone completely covered the lesion and the minimal ablative margin was > 5 mm . Fig. 5 a , b One lesion was clearly seen in the lung window and mediastinal window, which was pathologically confirmed as squamous cell carcinoma by biopsy. c 3D reconstruction revealed the size and margin of the tumor (purple color). d , e 2 days after ablation, CT showed no pneumothorax and pleural effusion, and the ablation zone was visible. f 3D reconstruction revealed the ablation zone and spatial relationships of the tumor (purple color). g , h 10 months after MWA, the ablative zone shrink and fibrosis had developed. i The images of pr-ablation ( c ) and postablation ( f ) were fused and displayed as ( i ). Quantitative measurement shown the minimal ablative margin was > 5 mm	3.841797	0.980957	sec[2]/sec[0]/sec[5]/p[0]	en	0.999997	34098894	https://doi.org/10.1186/s12880-021-00626-z	[ "ablation", "lung", "zone", "ablative", "margin", "biopsy", "squamous", "cell", "carcinoma", "time" ]	[ { "code": "QF01.10", "title": "Acquired absence of female genital organs" }, { "code": "9B73.3", "title": "Serous retinal detachment" }, { "code": "JA8C.Z", "title": "Maternal care related to premature separation of placenta, unspecified" }, { "code": "KA02.Y", "title": "Fetus or newborn affected by other specified complication of placenta" }, { "code": "5D40.00", "title": "Hypothyroidism postradioactive iodine ablation" }, { "code": "CB40.Y", "title": "Other specified diseases of the respiratory system" }, { "code": "LA75.1", "title": "Agenesis of lung" }, { "code": "CA40.Z", "title": "Pneumonia, organism unspecified" }, { "code": "CB41", "title": "Respiratory failure" }, { "code": "NB32.3Y", "title": "Other injury of lung" } ]	=== ICD-11 CODES FOUND === [QF01.10] Acquired absence of female genital organs Also known as: Acquired absence of female genital organs \| Acquired absence of cervix \| amputation of cervix \| Acquired absence of the uterus \| acquired uterine absence [9B73.3] Serous retinal detachment Definition: This occurs due to inflammation, injury or vascular abnormalities that results in fluid accumulating underneath the retina without the presence of a hole, tear, or break. Also known as: Serous retinal detachment \| serous retinal detachment, unspecified eye \| sensory retinal detachment \| Retinal detachment without retinal break \| Retinal detachment NOS Excludes: Central serous chorioretinopathy [JA8C.Z] Maternal care related to premature separation of placenta, unspecified Also known as: Maternal care related to premature separation of placenta, unspecified \| Maternal care related to premature separation of placenta \| ablatio placentae \| detachment of placenta \| placenta abruptio [KA02.Y] Fetus or newborn affected by other specified complication of placenta Also known as: Fetus or newborn affected by other specified complication of placenta \| Fetus or newborn affected by other forms of placental separation \| Ablatio placentae affecting fetus or newborn \| placenta ablation affecting fetus or newborn \| Abruptio placentae affecting fetus or newborn [5D40.00] Hypothyroidism postradioactive iodine ablation Also known as: Hypothyroidism postradioactive iodine ablation [CB40.Y] Other specified diseases of the respiratory system Also known as: Other specified diseases of the respiratory system \| Secondary respiratory disorders \| Respiratory disorders in diseases classified elsewhere \| Diseases of bronchus, not elsewhere classified \| Acquired bronchial diverticulum [LA75.1] Agenesis of lung Definition: This refers to the absence or rudimentary residua of an undeveloped lung. Also known as: Agenesis of lung \| Pulmonary agenesis \| absence of lung \| aplasia of lung \| apulmonism [CA40.Z] Pneumonia, organism unspecified Also known as: Pneumonia, organism unspecified \| Pneumonia \| infectious pneumonia \| PN - [pneumonia] \| lobar pneumonia NOS [CB41] Respiratory failure Definition: Respiratory failure is a life-threatening impairment of oxygenation or carbon dioxide (CO2) elimination. Respiratory failure may occur because of impaired gas exchange, decreased ventilation, or both. The level of oxygen in the blood becomes dangerously low or the level of carbon dioxide becomes dangerously high. Also known as: Respiratory failure \| lung failure NOS \| pulmonary failure Excludes: Acute respiratory distress syndrome \| Respiratory arrest \| Respiratory distress of newborn [NB32.3Y] Other injury of lung Also known as: Other injury of lung \| Haematoma of lung \| Traumatic hydropneumothorax \| Acute traumatic lung congestion \| Rupture of lung === GRAPH WALKS === --- Walk 1 --- [QF01.10] Acquired absence of female genital organs --RELATED_TO--> [?] Traumatic amputation of entire vulva --EXCLUDES--> [?] Female Genital Mutilation Def: A condition caused by procedures or other interventions for non-medical purposes. This condition is characterised by the partial or total removal of the external female genitalia or other injury to th... --- Walk 2 --- [QF01.10] Acquired absence of female genital organs --RELATED_TO--> [?] Female Genital Mutilation Def: A condition caused by procedures or other interventions for non-medical purposes. This condition is characterised by the partial or total removal of the external female genitalia or other injury to th... --PARENT--> [?] Other conditions of the genitourinary system Def: Any disorder characterised by pathological changes to the genitourinary system.... --- Walk 3 --- [9B73.3] Serous retinal detachment Def: This occurs due to inflammation, injury or vascular abnormalities that results in fluid accumulating underneath the retina without the presence of a hole, tear, or break.... --EXCLUDES--> [?] Central serous chorioretinopathy Def: This is an eye disease which causes visual impairment, often temporary, usually in one eye. When the disorder is active it is characterised by leakage of fluid under the retina that has a propensity t... --CHILD--> [?] Acute Central Serous Chorioretinopathy Def: This is an acute eye disease which causes visual impairment, often temporary, usually in one eye. When the disorder is active it is characterised by leakage of fluid under the retina that has a propen... --- Walk 4 --- [9B73.3] Serous retinal detachment Def: This occurs due to inflammation, injury or vascular abnormalities that results in fluid accumulating underneath the retina without the presence of a hole, tear, or break.... --EXCLUDES--> [?] Central serous chorioretinopathy Def: This is an eye disease which causes visual impairment, often temporary, usually in one eye. When the disorder is active it is characterised by leakage of fluid under the retina that has a propensity t... --CHILD--> [?] Acute Central Serous Chorioretinopathy Def: This is an acute eye disease which causes visual impairment, often temporary, usually in one eye. When the disorder is active it is characterised by leakage of fluid under the retina that has a propen... --- Walk 5 --- [JA8C.Z] Maternal care related to premature separation of placenta, unspecified --PARENT--> [JA8C] Maternal care related to premature separation of placenta --CHILD--> [JA8C.Y] Other specified maternal care related to premature separation of placenta --- Walk 6 --- [JA8C.Z] Maternal care related to premature separation of placenta, unspecified --PARENT--> [JA8C] Maternal care related to premature separation of placenta --CHILD--> [JA8C.Z] Maternal care related to premature separation of placenta, unspecified	[ "[QF01.10] Acquired absence of female genital organs\n --RELATED_TO--> [?] Traumatic amputation of entire vulva\n --EXCLUDES--> [?] Female Genital Mutilation\n Def: A condition caused by procedures or other interventions for non-medical purposes. This condition is characterised by the partial or total removal of the external female genitalia or other injury to th...", "[QF01.10] Acquired absence of female genital organs\n --RELATED_TO--> [?] Female Genital Mutilation\n Def: A condition caused by procedures or other interventions for non-medical purposes. This condition is characterised by the partial or total removal of the external female genitalia or other injury to th...\n --PARENT--> [?] Other conditions of the genitourinary system\n Def: Any disorder characterised by pathological changes to the genitourinary system....", "[9B73.3] Serous retinal detachment\n Def: This occurs due to inflammation, injury or vascular abnormalities that results in fluid accumulating underneath the retina without the presence of a hole, tear, or break....\n --EXCLUDES--> [?] Central serous chorioretinopathy\n Def: This is an eye disease which causes visual impairment, often temporary, usually in one eye. When the disorder is active it is characterised by leakage of fluid under the retina that has a propensity t...\n --CHILD--> [?] Acute Central Serous Chorioretinopathy\n Def: This is an acute eye disease which causes visual impairment, often temporary, usually in one eye. When the disorder is active it is characterised by leakage of fluid under the retina that has a propen...", "[9B73.3] Serous retinal detachment\n Def: This occurs due to inflammation, injury or vascular abnormalities that results in fluid accumulating underneath the retina without the presence of a hole, tear, or break....\n --EXCLUDES--> [?] Central serous chorioretinopathy\n Def: This is an eye disease which causes visual impairment, often temporary, usually in one eye. When the disorder is active it is characterised by leakage of fluid under the retina that has a propensity t...\n --CHILD--> [?] Acute Central Serous Chorioretinopathy\n Def: This is an acute eye disease which causes visual impairment, often temporary, usually in one eye. When the disorder is active it is characterised by leakage of fluid under the retina that has a propen...", "[JA8C.Z] Maternal care related to premature separation of placenta, unspecified\n --PARENT--> [JA8C] Maternal care related to premature separation of placenta\n --CHILD--> [JA8C.Y] Other specified maternal care related to premature separation of placenta", "[JA8C.Z] Maternal care related to premature separation of placenta, unspecified\n --PARENT--> [JA8C] Maternal care related to premature separation of placenta\n --CHILD--> [JA8C.Z] Maternal care related to premature separation of placenta, unspecified" ]	QF01.10	Acquired absence of female genital organs	[ { "from_icd11": "9B73.3", "icd10_code": "H3323", "icd10_title": "Serous retinal detachment, bilateral" }, { "from_icd11": "9B73.3", "icd10_code": "H3320", "icd10_title": "Serous retinal detachment, unspecified eye" }, { "from_icd11": "9B73.3", "icd10_code": "H3322", "icd10_title": "Serous retinal detachment, left eye" }, { "from_icd11": "9B73.3", "icd10_code": "H3321", "icd10_title": "Serous retinal detachment, right eye" }, { "from_icd11": "9B73.3", "icd10_code": "H332", "icd10_title": "Serous retinal detachment" }, { "from_icd11": "JA8C.Z", "icd10_code": "O4593", "icd10_title": "Premature separation of placenta, unspecified, third trimester" }, { "from_icd11": "JA8C.Z", "icd10_code": "O4592", "icd10_title": "Premature separation of placenta, unspecified, second trimester" }, { "from_icd11": "JA8C.Z", "icd10_code": "O458X3", "icd10_title": "Other premature separation of placenta, third trimester" }, { "from_icd11": "JA8C.Z", "icd10_code": "O458X2", "icd10_title": "Other premature separation of placenta, second trimester" }, { "from_icd11": "JA8C.Z", "icd10_code": "O4590", "icd10_title": "Premature separation of placenta, unspecified, unspecified trimester" }, { "from_icd11": "JA8C.Z", "icd10_code": "O458X1", "icd10_title": "Other premature separation of placenta, first trimester" }, { "from_icd11": "JA8C.Z", "icd10_code": "O4591", "icd10_title": "Premature separation of placenta, unspecified, first trimester" }, { "from_icd11": "JA8C.Z", "icd10_code": "O45", "icd10_title": "Premature separation of placenta [abruptio placentae]" }, { "from_icd11": "JA8C.Z", "icd10_code": "O458", "icd10_title": "Other premature separation of placenta" }, { "from_icd11": "JA8C.Z", "icd10_code": "O459", "icd10_title": "Premature separation of placenta, unspecified" } ]	H3323	Serous retinal detachment, bilateral
A 71-year-old male initially presented with the chief complaint of oral cavity mass. Notably, he had 30 pack-years smoking history. CT neck demonstrated right-sided tongue and floor of mouth mass, and possible metastatic disease within two right-sided cervical lymph nodes. He underwent a PET scan, which confirmed a hypermetabolic mass in the oral cavity and ipsilateral nodal disease. No sign of distant disease was identified at that time. He underwent a total glossectomy and bilateral cervical lymph node dissection. Pathology revealed an invasive, keratinizing, well-differentiated squamous cell carcinoma, with and metastatic carcinoma involving bilateral level 2-4 lymph nodes. A p16 immunohistochemical stain was negative. The tumor was staged as pT3 pN3b. Subsequently, the patient received adjuvant therapy. He presented for his regular follow-up 18 months after completion of adjuvant chemotherapy and radiation. Surveillance chest computed tomography (CT) scan revealed a right upper lobe endobronchial lesion and right hilar lymphadenopathy. The biopsy showed metastatic SCC in the right upper lobe of the lung. Imaging performed five months later showed newly developed pulmonary nodules representing additional sites of metastatic disease. In addition, abdominal and pelvic CT demonstrated newly developed renal masses, left adrenal mass, and pancreatic mass, also likely representing metastatic disease .	3.873047	0.984375	sec[2]/p[0]	en	0.999998	34307220	https://doi.org/10.4322/acr.2021.257	[ "metastatic", "lymph", "oral", "cavity", "sided", "cervical", "nodes", "scan", "carcinoma", "adjuvant" ]	[ { "code": "2D4Z", "title": "Unspecified malignant neoplasms of unspecified sites" }, { "code": "5C64.5", "title": "Disorders of calcium metabolism" }, { "code": "2E2Z", "title": "Malignant neoplasm metastasis, unspecified" }, { "code": "2E03", "title": "Malignant neoplasm metastasis in bone or bone marrow" }, { "code": "2D70", "title": "Malignant neoplasm metastasis in lung" }, { "code": "BD9Z", "title": "Disorders of lymphatic vessels or lymph nodes, unspecified" }, { "code": "BD90.Z", "title": "Lymphadenitis, unspecified" }, { "code": "BD90.Y", "title": "Other specified lymphadenitis" }, { "code": "BD9Y", "title": "Other specified disorders of lymphatic vessels or lymph nodes" }, { "code": "MA01.Z", "title": "Enlarged lymph nodes, unspecified" } ]	=== ICD-11 CODES FOUND === [2D4Z] Unspecified malignant neoplasms of unspecified sites Also known as: Unspecified malignant neoplasms of unspecified sites \| malignancy of unspecified site \| malignancy unspecified primary site \| malignant growth of unspecified site \| malignant mass of unspecified site [5C64.5] Disorders of calcium metabolism Definition: This refers to disorders in the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcaemia or hypocalcaemia, both of which can have important consequences for health. Also known as: Disorders of calcium metabolism \| Calcinosis \| general calcification \| heterotopic calcification \| metastatic calcification Excludes: Hyperparathyroidism \| Chondrocalcinosis [2E2Z] Malignant neoplasm metastasis, unspecified Also known as: Malignant neoplasm metastasis, unspecified \| secondary malignant neoplasm \| metastasis \| metastases \| disseminated metastases [2E03] Malignant neoplasm metastasis in bone or bone marrow Definition: The spread of a malignant neoplasm from a primary site to the skeletal system. The majority of metastatic neoplasms to the bone are carcinomas. Also known as: Malignant neoplasm metastasis in bone or bone marrow \| bone metastasis \| bony metastasis \| osseous metastasis \| secondary cancer of bone [2D70] Malignant neoplasm metastasis in lung Also known as: Malignant neoplasm metastasis in lung \| metastasis in lung \| pulmonary metastasis \| secondary cancer in lung \| secondary malignant tumour in lung Excludes: Malignant neoplasms of bronchus or lung [BD9Z] Disorders of lymphatic vessels or lymph nodes, unspecified Also known as: Disorders of lymphatic vessels or lymph nodes, unspecified \| Lymphatic system disorders \| lymph disease NOS \| lymph gland disease \| Lymphatic system disease NOS [BD90.Z] Lymphadenitis, unspecified Also known as: Lymphadenitis, unspecified \| Lymphadenitis \| adenitis NOS \| inflammation of gland \| lymphatic gland inflammation [BD90.Y] Other specified lymphadenitis Also known as: Other specified lymphadenitis \| Dermatopathic lymphadenopathy \| lipomelanotic reticulosis \| Infective inguinal bubo \| bubo [BD9Y] Other specified disorders of lymphatic vessels or lymph nodes Also known as: Other specified disorders of lymphatic vessels or lymph nodes \| Chylous cyst \| Mesentery chylous cyst \| Peritoneum chylous cyst \| Lymphocele [MA01.Z] Enlarged lymph nodes, unspecified Also known as: Enlarged lymph nodes, unspecified \| Enlarged lymph nodes \| swollen glands \| Lymphadenopathy \| adenopathy === GRAPH WALKS === --- Walk 1 --- [2D4Z] Unspecified malignant neoplasms of unspecified sites --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites --CHILD--> [2D42] Malignant neoplasms of ill-defined sites Def: Malignant neoplasms of ill defined sites is used for cases where the documentation refers to a site that includes multiple organ systems and tissue types that should be coded separately.... --- Walk 2 --- [2D4Z] Unspecified malignant neoplasms of unspecified sites --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites --EXCLUDES--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --- Walk 3 --- [5C64.5] Disorders of calcium metabolism Def: This refers to disorders in the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcaemia or hypocalcaemia, both of which can have important ... --RELATED_TO--> [?] Nephrocalcinosis Def: A condition of the kidney, caused by previous inflammation or degeneration when accompanied by previous renal failure. This condition is characterised by renal lithiasis, or calcium-based deposition i... --PARENT--> [?] Renal tubulo-interstitial diseases Def: Any disease characterised by pathological changes to the renal tubules and interstitial tissues.... --- Walk 4 --- [5C64.5] Disorders of calcium metabolism Def: This refers to disorders in the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcaemia or hypocalcaemia, both of which can have important ... --RELATED_TO--> [?] Nephrocalcinosis Def: A condition of the kidney, caused by previous inflammation or degeneration when accompanied by previous renal failure. This condition is characterised by renal lithiasis, or calcium-based deposition i... --CHILD--> [?] Fetal nephrocalcinosis --- Walk 5 --- [2E2Z] Malignant neoplasm metastasis, unspecified --PARENT--> [?] Malignant neoplasm metastases Def: Spread of a malignant neoplasm into secondary sites.... --CHILD--> [2D52] Malignant neoplasm metastasis in spinal cord, cranial nerves or paraspinal nerves --- Walk 6 --- [2E2Z] Malignant neoplasm metastasis, unspecified --PARENT--> [?] Malignant neoplasm metastases Def: Spread of a malignant neoplasm into secondary sites.... --CHILD--> [2D50] Malignant neoplasm metastasis in brain Def: A malignant neoplasm that has spread to the brain from another anatomic site or system. The majority are carcinomas (usually lung or breast carcinomas)....	[ "[2D4Z] Unspecified malignant neoplasms of unspecified sites\n --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites\n --CHILD--> [2D42] Malignant neoplasms of ill-defined sites\n Def: Malignant neoplasms of ill defined sites is used for cases where the documentation refers to a site that includes multiple organ systems and tissue types that should be coded separately....", "[2D4Z] Unspecified malignant neoplasms of unspecified sites\n --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites\n --EXCLUDES--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...", "[5C64.5] Disorders of calcium metabolism\n Def: This refers to disorders in the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcaemia or hypocalcaemia, both of which can have important ...\n --RELATED_TO--> [?] Nephrocalcinosis\n Def: A condition of the kidney, caused by previous inflammation or degeneration when accompanied by previous renal failure. This condition is characterised by renal lithiasis, or calcium-based deposition i...\n --PARENT--> [?] Renal tubulo-interstitial diseases\n Def: Any disease characterised by pathological changes to the renal tubules and interstitial tissues....", "[5C64.5] Disorders of calcium metabolism\n Def: This refers to disorders in the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcaemia or hypocalcaemia, both of which can have important ...\n --RELATED_TO--> [?] Nephrocalcinosis\n Def: A condition of the kidney, caused by previous inflammation or degeneration when accompanied by previous renal failure. This condition is characterised by renal lithiasis, or calcium-based deposition i...\n --CHILD--> [?] Fetal nephrocalcinosis", "[2E2Z] Malignant neoplasm metastasis, unspecified\n --PARENT--> [?] Malignant neoplasm metastases\n Def: Spread of a malignant neoplasm into secondary sites....\n --CHILD--> [2D52] Malignant neoplasm metastasis in spinal cord, cranial nerves or paraspinal nerves", "[2E2Z] Malignant neoplasm metastasis, unspecified\n --PARENT--> [?] Malignant neoplasm metastases\n Def: Spread of a malignant neoplasm into secondary sites....\n --CHILD--> [2D50] Malignant neoplasm metastasis in brain\n Def: A malignant neoplasm that has spread to the brain from another anatomic site or system. The majority are carcinomas (usually lung or breast carcinomas)...." ]	2D4Z	Unspecified malignant neoplasms of unspecified sites	[ { "from_icd11": "2D4Z", "icd10_code": "C802", "icd10_title": "Malignant neoplasm associated with transplanted organ" }, { "from_icd11": "2D4Z", "icd10_code": "C7650", "icd10_title": "Malignant neoplasm of unspecified lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7642", "icd10_title": "Malignant neoplasm of left upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7640", "icd10_title": "Malignant neoplasm of unspecified upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7652", "icd10_title": "Malignant neoplasm of left lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7651", "icd10_title": "Malignant neoplasm of right lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7641", "icd10_title": "Malignant neoplasm of right upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C801", "icd10_title": "Malignant (primary) neoplasm, unspecified" }, { "from_icd11": "2D4Z", "icd10_code": "C768", "icd10_title": "Malignant neoplasm of other specified ill-defined sites" }, { "from_icd11": "2D4Z", "icd10_code": "C761", "icd10_title": "Malignant neoplasm of thorax" }, { "from_icd11": "2D4Z", "icd10_code": "C762", "icd10_title": "Malignant neoplasm of abdomen" }, { "from_icd11": "2D4Z", "icd10_code": "C763", "icd10_title": "Malignant neoplasm of pelvis" }, { "from_icd11": "2D4Z", "icd10_code": "C800", "icd10_title": "Disseminated malignant neoplasm, unspecified" }, { "from_icd11": "2D4Z", "icd10_code": "C76-C80", "icd10_title": "" }, { "from_icd11": "2D4Z", "icd10_code": "C76", "icd10_title": "Malignant neoplasm of other and ill-defined sites" } ]	C802	Malignant neoplasm associated with transplanted organ
During hospital admission examinations were performed to determine ischemic stroke etiology. Ultrasound of the pre- and intra- cerebral vessels showed no significant stenoses or occlusions. Five day in-hospital cardiac rhythm monitoring showed sinus rhythm without any signs of atrial fibrillation and or other arrythmia. The patient underwent a Trans- Thoracic Echocardiography (TTE) which was normal and a Trans- Esophageal Echocardiography (TEE) where a patent foramen ovale was detected (PFO). The right to left shunting was visualized on color doppler and whilst using contrast . A blood work up during admission showed a normal ESR, normal levels of Immunoglobulin G and M, normal levels of Protein C and S and normal Factor Xa activity. Immunological assays did not detect the presence of rheumatoid factor, ANCA, ANA, anti-CCP antibodies. Furthermore, no factor V Leiden mutation was detected nor the presence of Lupus anticoagulant. The only abnormal finding was an elevated D-dimer of 1.2 mg/L (normal range 0.2–0.6 mg/L). A full body CT was performed including a CTPA and a CT venography of the lower extremities. The full body CT showed no signs of malignancy. The CTPA showed no evidence of pulmonary embolus and the CT venography of the lower extremities ruled out deep vein thrombosis (DVT). Fig. 5 Echocardiography showing a PFO using agitated sodium chloride contrast (left) and on colour doppler (right)	3.96875	0.970703	sec[1]/p[8]	en	0.999997	34407847	https://doi.org/10.1186/s12959-021-00304-8	[ "echocardiography", "factor", "rhythm", "trans", "doppler", "using", "contrast", "presence", "full", "body" ]	[ { "code": "3B14.0", "title": "Hereditary deficiency of factor I" }, { "code": "3B14.Z", "title": "Other inherited coagulation factor deficiency with bleeding tendency, unspecified" }, { "code": "3B14.1", "title": "Hereditary factor X deficiency" }, { "code": "3B11.Z", "title": "Hereditary factor IX deficiency, unspecified" }, { "code": "PB6Z", "title": "Unspecified unintentional cause of morbidity or mortality" }, { "code": "MC81.Z", "title": "Abnormalities of heart beat, unspecified" }, { "code": "BC9Y", "title": "Other specified cardiac arrhythmia" }, { "code": "MC81.Y", "title": "Other specified abnormalities of heart beat" }, { "code": "BC7Z", "title": "Ventricular rhythm disturbance, unspecified" }, { "code": "BC90", "title": "Rhythm disturbance at level of atrioventricular junction" } ]	=== ICD-11 CODES FOUND === [3B14.0] Hereditary deficiency of factor I Definition: Congenital deficiencies of fibrinogen are coagulation disorders characterised by bleeding symptoms ranging from mild to severe resulting from reduced quantity and/or quality of circulating fibrinogen. Afibrinogenaemia (complete absence of fibrinogen) and hypofibrinogenaemia (reduced plasma fibrinogen concentration) correspond to quantitative anomalies of fibrinogen while dysfibrinogenaemia corresponds to a functional anomaly of fibrinogen. Hypo- and dysfibrinogenaemia may be frequently combined Also known as: Hereditary deficiency of factor I \| Deficiency of factor 1 \| Hereditary fibrinogen deficiency \| Deficiency of fibrinogen \| congenital fibrinogenopenia [3B14.Z] Other inherited coagulation factor deficiency with bleeding tendency, unspecified Also known as: Other inherited coagulation factor deficiency with bleeding tendency, unspecified \| Other inherited coagulation factor deficiency with bleeding tendency \| Hereditary factor V deficiency \| Proaccelerin deficiency \| Owren disease [3B14.1] Hereditary factor X deficiency Definition: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms. Also known as: Hereditary factor X deficiency \| Congenital Stuart factor deficiency \| Stuart-Prower factor deficiency \| Deficiency of factor X \| congenital factor x deficiency [3B11.Z] Hereditary factor IX deficiency, unspecified Also known as: Hereditary factor IX deficiency, unspecified \| Hereditary factor IX deficiency \| factor 9 deficiency \| factor IX deficiency \| hereditary factor IX deficiency disease [PB6Z] Unspecified unintentional cause of morbidity or mortality Also known as: Unspecified unintentional cause of morbidity or mortality \| Exposure to unspecified factor \| Exposure to unspecified factor causing fracture \| Exposure to unspecified factor causing other and unspecified injury \| accidental cause NOS [MC81.Z] Abnormalities of heart beat, unspecified Also known as: Abnormalities of heart beat, unspecified \| Abnormalities of heart beat \| abnormal heart rate \| abnormal rhythm disorder \| abnormal rhythms [BC9Y] Other specified cardiac arrhythmia Also known as: Other specified cardiac arrhythmia \| Ectopic arrhythmia \| ectopic cardiac arrhythmia \| ectopic atrial pacemaker \| ectopic rhythm NOS [MC81.Y] Other specified abnormalities of heart beat Also known as: Other specified abnormalities of heart beat \| Coupled rhythm \| Gallop rhythm \| Pulse, alternating \| Pulse, bigeminal [BC7Z] Ventricular rhythm disturbance, unspecified Also known as: Ventricular rhythm disturbance, unspecified [BC90] Rhythm disturbance at level of atrioventricular junction Also known as: Rhythm disturbance at level of atrioventricular junction \| atrioventricular junctional rhythm \| AV - [atrioventricular] junctional rhythm \| atrioventricular nodal rhythm === GRAPH WALKS === --- Walk 1 --- [3B14.0] Hereditary deficiency of factor I Def: Congenital deficiencies of fibrinogen are coagulation disorders characterised by bleeding symptoms ranging from mild to severe resulting from reduced quantity and/or quality of circulating fibrinogen.... --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui... --CHILD--> [3B14.1] Hereditary factor X deficiency Def: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms.... --- Walk 2 --- [3B14.0] Hereditary deficiency of factor I Def: Congenital deficiencies of fibrinogen are coagulation disorders characterised by bleeding symptoms ranging from mild to severe resulting from reduced quantity and/or quality of circulating fibrinogen.... --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui... --PARENT--> [?] Congenital or constitutional haemorrhagic condition Def: A condition caused by determinants arising during the antenatal period or genetically inherited factors, leading to defects in clotting mechanisms or abnormalities causing structural flaws in the bloo... --- Walk 3 --- [3B14.Z] Other inherited coagulation factor deficiency with bleeding tendency, unspecified --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui... --PARENT--> [?] Congenital or constitutional haemorrhagic condition Def: A condition caused by determinants arising during the antenatal period or genetically inherited factors, leading to defects in clotting mechanisms or abnormalities causing structural flaws in the bloo... --- Walk 4 --- [3B14.Z] Other inherited coagulation factor deficiency with bleeding tendency, unspecified --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui... --CHILD--> [3B14.1] Hereditary factor X deficiency Def: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms.... --- Walk 5 --- [3B14.1] Hereditary factor X deficiency Def: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms.... --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui... --CHILD--> [3B14.1] Hereditary factor X deficiency Def: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms.... --- Walk 6 --- [3B14.1] Hereditary factor X deficiency Def: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms.... --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui... --PARENT--> [?] Congenital or constitutional haemorrhagic condition Def: A condition caused by determinants arising during the antenatal period or genetically inherited factors, leading to defects in clotting mechanisms or abnormalities causing structural flaws in the bloo...	[ "[3B14.0] Hereditary deficiency of factor I\n Def: Congenital deficiencies of fibrinogen are coagulation disorders characterised by bleeding symptoms ranging from mild to severe resulting from reduced quantity and/or quality of circulating fibrinogen....\n --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency\n Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui...\n --CHILD--> [3B14.1] Hereditary factor X deficiency\n Def: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms....", "[3B14.0] Hereditary deficiency of factor I\n Def: Congenital deficiencies of fibrinogen are coagulation disorders characterised by bleeding symptoms ranging from mild to severe resulting from reduced quantity and/or quality of circulating fibrinogen....\n --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency\n Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui...\n --PARENT--> [?] Congenital or constitutional haemorrhagic condition\n Def: A condition caused by determinants arising during the antenatal period or genetically inherited factors, leading to defects in clotting mechanisms or abnormalities causing structural flaws in the bloo...", "[3B14.Z] Other inherited coagulation factor deficiency with bleeding tendency, unspecified\n --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency\n Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui...\n --PARENT--> [?] Congenital or constitutional haemorrhagic condition\n Def: A condition caused by determinants arising during the antenatal period or genetically inherited factors, leading to defects in clotting mechanisms or abnormalities causing structural flaws in the bloo...", "[3B14.Z] Other inherited coagulation factor deficiency with bleeding tendency, unspecified\n --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency\n Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui...\n --CHILD--> [3B14.1] Hereditary factor X deficiency\n Def: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms....", "[3B14.1] Hereditary factor X deficiency\n Def: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms....\n --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency\n Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui...\n --CHILD--> [3B14.1] Hereditary factor X deficiency\n Def: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms....", "[3B14.1] Hereditary factor X deficiency\n Def: Congenital factor X deficiency is an inherited bleeding disorder with a decreased antigen and/or activity of factor X (FX) and characterised by mild to severe bleeding symptoms....\n --PARENT--> [3B14] Other inherited coagulation factor deficiency with bleeding tendency\n Def: Any disease caused by genetically inherited mutations leading to lack of coagulation factors in the blood not elsewhere classified. These diseases are characterised by increased haemorrhaging and brui...\n --PARENT--> [?] Congenital or constitutional haemorrhagic condition\n Def: A condition caused by determinants arising during the antenatal period or genetically inherited factors, leading to defects in clotting mechanisms or abnormalities causing structural flaws in the bloo..." ]	3B14.0	Hereditary deficiency of factor I	[ { "from_icd11": "3B14.0", "icd10_code": "D682", "icd10_title": "Hereditary deficiency of other clotting factors" }, { "from_icd11": "3B11.Z", "icd10_code": "D67", "icd10_title": "Hereditary factor IX deficiency" }, { "from_icd11": "PB6Z", "icd10_code": "W312XXA", "icd10_title": "Contact with powered woodworking and forming machines, initial encounter" }, { "from_icd11": "PB6Z", "icd10_code": "W311XXA", "icd10_title": "Contact with metalworking machines, initial encounter" }, { "from_icd11": "PB6Z", "icd10_code": "W3189XA", "icd10_title": "Contact with other specified machinery, initial encounter" }, { "from_icd11": "PB6Z", "icd10_code": "W319XXS", "icd10_title": "Contact with unspecified machinery, sequela" }, { "from_icd11": "PB6Z", "icd10_code": "W3182XA", "icd10_title": "Contact with other commercial machinery, initial encounter" }, { "from_icd11": "PB6Z", "icd10_code": "W3182XS", "icd10_title": "Contact with other commercial machinery, sequela" }, { "from_icd11": "PB6Z", "icd10_code": "W3089XA", "icd10_title": "Contact with other specified agricultural machinery, initial encounter" }, { "from_icd11": "PB6Z", "icd10_code": "W309XXS", "icd10_title": "Contact with unspecified agricultural machinery, sequela" }, { "from_icd11": "PB6Z", "icd10_code": "W3089XS", "icd10_title": "Contact with other specified agricultural machinery, sequela" }, { "from_icd11": "PB6Z", "icd10_code": "W310XXA", "icd10_title": "Contact with mining and earth-drilling machinery, initial encounter" }, { "from_icd11": "PB6Z", "icd10_code": "W3183XA", "icd10_title": "Contact with special construction vehicle in stationary use, initial encounter" }, { "from_icd11": "PB6Z", "icd10_code": "W3183XD", "icd10_title": "Contact with special construction vehicle in stationary use, subsequent encounter" }, { "from_icd11": "PB6Z", "icd10_code": "W319XXA", "icd10_title": "Contact with unspecified machinery, initial encounter" } ]	D682	Hereditary deficiency of other clotting factors
On examination, the patient was fully alert, oriented and vitally stable with SpO2 of 98%. The extraocular movements were intact in all directions with normal convergence. The pupils were bilaterally equal and responsive to light and accommodation. Her vision was normal as well. There was no nystagmus in any direction. Bell´s phenomenon was observed in the left eye, with loss of left-sided nasolabial folds and forehead wrinkles, indicating towards lower motor neuron type of facial palsy on the left side. Gag reflex was also weak with a right-sided deviation of uvula. No fasciculations were observed on tongue protrusion. The facial sensation was intact. Rest of the cranial nerve examination was unremarkable. On motor examination of upper limbs, the bulk was normal bilaterally. Hypotonia was observed in both upper limbs. Muscle strength was assessed through the Medical Research Council (MRC) scale, which was 2/5, proximally and distally in both limbs. Deep tendon reflex (DTR) was significantly reduced. The power of neck muscles was reduced with a few episodes of head drops. The movements of the neck, however, was completely impaired against resistance. On lower motor examinations, the bulk, tone, power and DTR were normal. The sensory and cerebellar examinations were also unremarkable. There was no sign of meningeal irritation. Cardiovascular, respiratory and abdominal examinations were unremarkable.	3.865234	0.980957	sec[1]/p[1]	en	0.999998	34367435	https://doi.org/10.11604/pamj.2021.38.356.28363	[ "motor", "unremarkable", "limbs", "examinations", "movements", "intact", "bilaterally", "sided", "facial", "reflex" ]	[ { "code": "MB47.0", "title": "Abnormal reflex" }, { "code": "PA2Z", "title": "Unintentional land transport injury event unknown whether traffic or nontraffic injuring a user of unspecified transport" }, { "code": "DA21.Z", "title": "Motility disorders of oesophagus, unspecified" }, { "code": "PA03", "title": "Unintentional land transport traffic event injuring a motor cyclist" }, { "code": "PA20", "title": "Unintentional land transport event unknown whether traffic or nontraffic injuring a pedestrian" }, { "code": "ND56.1", "title": "Open wound of unspecified body region" }, { "code": "LB9Z", "title": "Structural developmental anomalies of the skeleton, unspecified" }, { "code": "FB56.6", "title": "Other specified soft tissue disorders" }, { "code": "5B51&XS25", "title": "Severe wasting in infants, children or adolescents" }, { "code": "ND55", "title": "Other injuries of leg, level unspecified" } ]	=== ICD-11 CODES FOUND === [MB47.0] Abnormal reflex Also known as: Abnormal reflex \| reflex disorder \| reflex disturbance \| motor disturbance \| motor disorder Excludes: vasovagal reaction or syncope \| hyperactive gag reflex \| abnormal pupillary reflex [PA2Z] Unintentional land transport injury event unknown whether traffic or nontraffic injuring a user of unspecified transport Also known as: Unintentional land transport injury event unknown whether traffic or nontraffic injuring a user of unspecified transport \| unintentional land transport injury event unknown whether on road or off-road \| land transport accident NOS \| motor vehicle accident NOS \| MVA - [motor vehicle accident] NOS [DA21.Z] Motility disorders of oesophagus, unspecified Also known as: Motility disorders of oesophagus, unspecified \| Motility disorders of oesophagus \| Dyskinesia of oesophagus \| oesophageal dysmotility \| oesophageal motility disorder [PA03] Unintentional land transport traffic event injuring a motor cyclist Also known as: Unintentional land transport traffic event injuring a motor cyclist \| motorcycle rider injured in transport accident \| unintentional land transport accident motorbike \| motorbike accident \| motorbike traffic accident Excludes: Unintentional land transport traffic event injuring an occupant of a low powered passenger vehicle [PA20] Unintentional land transport event unknown whether traffic or nontraffic injuring a pedestrian Also known as: Unintentional land transport event unknown whether traffic or nontraffic injuring a pedestrian \| unintentional crash injuring a pedestrian, unknown whether on road \| pedestrian accident NOS \| pedestrian struck by motor vehicle \| pedestrian struck by vehicle [ND56.1] Open wound of unspecified body region Also known as: Open wound of unspecified body region \| cut NOS \| open wound NOS \| penetrating wound NOS \| Puncture wound with foreign body unspecified body region Excludes: Traumatic amputations involving multiple body regions \| Open wounds involving multiple body regions \| traumatic amputation NOS [LB9Z] Structural developmental anomalies of the skeleton, unspecified Also known as: Structural developmental anomalies of the skeleton, unspecified \| Abnormal bone development \| skeletal anomaly NOS [FB56.6] Other specified soft tissue disorders Also known as: Other specified soft tissue disorders \| Fat necrosis \| fatty necrosis \| Profichet's disease \| Sloughing of fascia [ND55] Other injuries of leg, level unspecified Also known as: Other injuries of leg, level unspecified \| other injuries of lower limb, level unspecified \| Superficial injury of leg, level unspecified \| Abrasion of leg, level unspecified \| Contusion of leg, level unspecified Excludes: Fracture of leg, level unspecified \| Injuries involving multiple body regions === GRAPH WALKS === --- Walk 1 --- [MB47.0] Abnormal reflex --PARENT--> [MB47] Abnormality of tonus or reflex --CHILD--> [MB47.0] Abnormal reflex --- Walk 2 --- [MB47.0] Abnormal reflex --EXCLUDES--> [?] Syncope or collapse Def: Syncope is also called fainting, temporary loss of consciousness. Syncope and collapse is temporary loss of consciousness with a fall down.... --EXCLUDES--> [?] Shock during or following labour or delivery Def: A syndrome characterised by systemic cellular hypoxia and organ dysfunction as a result of hypoperfusion following labour and delivery. This syndrome is caused by haemorrhage, vomiting, diarrhoea, ina... --- Walk 3 --- [PA2Z] Unintentional land transport injury event unknown whether traffic or nontraffic injuring a user of unspecified transport --PARENT--> [?] Unintentional land transport injury event unknown whether road traffic or off-road nontraffic --CHILD--> [PA21] Unintentional land transport event unknown whether traffic or nontraffic injuring the user of a pedestrian conveyance --- Walk 4 --- [PA2Z] Unintentional land transport injury event unknown whether traffic or nontraffic injuring a user of unspecified transport --PARENT--> [?] Unintentional land transport injury event unknown whether road traffic or off-road nontraffic --CHILD--> [PA22] Unintentional land transport event unknown whether traffic or nontraffic injuring a pedal cyclist --- Walk 5 --- [DA21.Z] Motility disorders of oesophagus, unspecified --PARENT--> [DA21] Motility disorders of oesophagus Def: This group incorporates oesophageal disorders due to disturbances of oesophageal motor function.... --PARENT--> [?] Diseases of oesophagus --- Walk 6 --- [DA21.Z] Motility disorders of oesophagus, unspecified --PARENT--> [DA21] Motility disorders of oesophagus Def: This group incorporates oesophageal disorders due to disturbances of oesophageal motor function.... --CHILD--> [DA21.1] Motility disorder of cervical or upper oesophagus Def: Motility disorder of cervical and upper oesophagus is a condition characterised by choke, swallow air, regurgitate fluid into the nose, or experience discomfort in swallowing food due to incompetence ...	[ "[MB47.0] Abnormal reflex\n --PARENT--> [MB47] Abnormality of tonus or reflex\n --CHILD--> [MB47.0] Abnormal reflex", "[MB47.0] Abnormal reflex\n --EXCLUDES--> [?] Syncope or collapse\n Def: Syncope is also called fainting, temporary loss of consciousness. Syncope and collapse is temporary loss of consciousness with a fall down....\n --EXCLUDES--> [?] Shock during or following labour or delivery\n Def: A syndrome characterised by systemic cellular hypoxia and organ dysfunction as a result of hypoperfusion following labour and delivery. This syndrome is caused by haemorrhage, vomiting, diarrhoea, ina...", "[PA2Z] Unintentional land transport injury event unknown whether traffic or nontraffic injuring a user of unspecified transport\n --PARENT--> [?] Unintentional land transport injury event unknown whether road traffic or off-road nontraffic\n --CHILD--> [PA21] Unintentional land transport event unknown whether traffic or nontraffic injuring the user of a pedestrian conveyance", "[PA2Z] Unintentional land transport injury event unknown whether traffic or nontraffic injuring a user of unspecified transport\n --PARENT--> [?] Unintentional land transport injury event unknown whether road traffic or off-road nontraffic\n --CHILD--> [PA22] Unintentional land transport event unknown whether traffic or nontraffic injuring a pedal cyclist", "[DA21.Z] Motility disorders of oesophagus, unspecified\n --PARENT--> [DA21] Motility disorders of oesophagus\n Def: This group incorporates oesophageal disorders due to disturbances of oesophageal motor function....\n --PARENT--> [?] Diseases of oesophagus", "[DA21.Z] Motility disorders of oesophagus, unspecified\n --PARENT--> [DA21] Motility disorders of oesophagus\n Def: This group incorporates oesophageal disorders due to disturbances of oesophageal motor function....\n --CHILD--> [DA21.1] Motility disorder of cervical or upper oesophagus\n Def: Motility disorder of cervical and upper oesophagus is a condition characterised by choke, swallow air, regurgitate fluid into the nose, or experience discomfort in swallowing food due to incompetence ..." ]	MB47.0	Abnormal reflex	[ { "from_icd11": "MB47.0", "icd10_code": "R292", "icd10_title": "Abnormal reflex" }, { "from_icd11": "PA2Z", "icd10_code": "V988XXS", "icd10_title": "Other specified transport accidents, sequela" }, { "from_icd11": "PA2Z", "icd10_code": "V99XXXD", "icd10_title": "Unspecified transport accident, subsequent encounter" }, { "from_icd11": "PA2Z", "icd10_code": "V988XXA", "icd10_title": "Other specified transport accidents, initial encounter" }, { "from_icd11": "PA2Z", "icd10_code": "V99XXXS", "icd10_title": "Unspecified transport accident, sequela" }, { "from_icd11": "PA2Z", "icd10_code": "V80010A", "icd10_title": "Animal-rider injured by fall from or being thrown from horse in noncollision accident, initial encounter" }, { "from_icd11": "PA2Z", "icd10_code": "V899XXS", "icd10_title": "Person injured in unspecified vehicle accident, sequela" }, { "from_icd11": "PA2Z", "icd10_code": "V80919A", "icd10_title": "Animal-rider injured in unspecified transport accident, initial encounter" }, { "from_icd11": "PA2Z", "icd10_code": "V899XXA", "icd10_title": "Person injured in unspecified vehicle accident, initial encounter" }, { "from_icd11": "PA2Z", "icd10_code": "V8011XA", "icd10_title": "Animal-rider injured in collision with pedestrian or animal, initial encounter" }, { "from_icd11": "PA2Z", "icd10_code": "V8041XA", "icd10_title": "Animal-rider injured in collision with car, pick-up truck, van, heavy transport vehicle or bus, initial encounter" }, { "from_icd11": "PA2Z", "icd10_code": "V8012XA", "icd10_title": "Occupant of animal-drawn vehicle injured in collision with pedestrian or animal, initial encounter" }, { "from_icd11": "PA2Z", "icd10_code": "V8021XA", "icd10_title": "Animal-rider injured in collision with pedal cycle, initial encounter" }, { "from_icd11": "PA2Z", "icd10_code": "V899", "icd10_title": "Person injured in unspecified vehicle accident" }, { "from_icd11": "PA2Z", "icd10_code": "V98-V99", "icd10_title": "" } ]	R292	Abnormal reflex
A 48-year-old female who had undergone bilateral RK (i.e., 8 corneal incisions per eye) 27-years previously presented with the complaints of pain and visual loss in her right eye after being diagnosed with bacterial keratitis by her primary care physician. She was employed as a staff member at a nursing facility; i.e., an intermediary facility providing care between hospitals and homes. Her specific job entailed providing assistance to the elderly, including bathing, toileting, meals, and transfers, as well as facial, oral, skin, and hair cleaning, which put her in direct contact with those subjects. Post RK, she had not undergone any long-term follow-up examinations due to the good surgical outcome and the postoperative course being stable and satisfactory for 27 years. However, at 5 days prior to admission, she suddenly became aware of pain in her right eye, followed by redness and foreign body sensation (1 day later) and blurred vision (2 days later). Although she had been diagnosed with bacterial keratitis by her primary care physician at another clinic, she was not prescribed any eye-drop medication due to the secondary medical care receiving site being closer and easier for her to visit. Following initial examination at the secondary medical care receiving site, she was immediately referred for treatment at the emergency room of Kyoto Prefectural University of Medicine Hospital, Kyoto, Japan.	3.652344	0.98584	sec[1]/p[0]	en	0.999997	34917857	https://doi.org/10.1016/j.ajoc.2021.101240	[ "undergone", "pain", "diagnosed", "bacterial", "keratitis", "physician", "facility", "providing", "receiving", "site" ]	[ { "code": "PL11.5", "title": "Procedure undertaken at wrong site or wrong side, as mode of injury or harm" }, { "code": "MG3Z", "title": "Pain, unspecified" }, { "code": "8E43.Z", "title": "Pain disorders, unspecified" }, { "code": "MG31.Z", "title": "Acute pain, unspecified" }, { "code": "MG30.Z", "title": "Chronic pain, unspecified" }, { "code": "FB56.2", "title": "Myalgia" }, { "code": "1F45", "title": "Malaria without parasitological confirmation" }, { "code": "RA01.1", "title": "COVID-19, virus not identified" }, { "code": "1C41", "title": "Bacterial infection of unspecified site" }, { "code": "1C4Z", "title": "Unspecified bacterial disease" } ]	=== ICD-11 CODES FOUND === [PL11.5] Procedure undertaken at wrong site or wrong side, as mode of injury or harm Also known as: Procedure undertaken at wrong site or wrong side, as mode of injury or harm \| operation performed on incorrect site \| surgery undergone on incorrect body part \| wrong surgery \| Performance of inappropriate operation Excludes: Patient received diagnostic test or treatment intended for another patient [MG3Z] Pain, unspecified Also known as: Pain, unspecified \| pain observations \| pain NOS \| generalised pain \| generalised pain, NOS [8E43.Z] Pain disorders, unspecified Also known as: Pain disorders, unspecified \| Pain disorders [MG31.Z] Acute pain, unspecified Also known as: Acute pain, unspecified \| Acute pain [MG30.Z] Chronic pain, unspecified Also known as: Chronic pain, unspecified \| Chronic pain [FB56.2] Myalgia Definition: This is a disorder characterised by pain in a muscle or group of muscles. Also known as: Myalgia \| muscle ache \| muscle soreness \| muscular pain \| myalgic Excludes: Chronic primary musculoskeletal pain \| Chronic secondary musculoskeletal pain [1F45] Malaria without parasitological confirmation Definition: Clinically diagnosed malaria without parasitological confirmation Also known as: Malaria without parasitological confirmation \| marsh fever \| remittent congestive fever \| coastal fever \| remittent gastric fever Includes: clinically diagnosed malaria without parasitological confirmation [RA01.1] COVID-19, virus not identified Also known as: COVID-19, virus not identified \| clinically diagnosed COVID-19 \| suspected COVID-19 \| probable COVID-19 \| clinical COVID-19 Excludes: COVID-19, virus identified \| Coronavirus infection, unspecified site \| Special screening examination for other viral diseases [1C41] Bacterial infection of unspecified site Also known as: Bacterial infection of unspecified site \| bacterial infection NOS \| disease caused by bacteria \| bacterial disease or disorder \| Haemophilus influenzae infection of unspecified site Excludes: meningococcal infection NOS \| chlamydial infection NOS \| rickettsial infection NOS [1C4Z] Unspecified bacterial disease Also known as: Unspecified bacterial disease === GRAPH WALKS === --- Walk 1 --- [PL11.5] Procedure undertaken at wrong site or wrong side, as mode of injury or harm --PARENT--> [PL11] Mode of injury or harm associated with a surgical or other medical procedure --PARENT--> [?] Causes of healthcare related harm or injury --- Walk 2 --- [PL11.5] Procedure undertaken at wrong site or wrong side, as mode of injury or harm --EXCLUDES--> [?] Patient received diagnostic test or treatment intended for another patient --EXCLUDES--> [?] Procedure undertaken at wrong site or wrong side, as mode of injury or harm --- Walk 3 --- [MG3Z] Pain, unspecified --PARENT--> [?] Pain --CHILD--> [MG31] Acute pain Def: Pain with a duration of less than 3 months. This code should be used only when there is no further specification of site.... --- Walk 4 --- [MG3Z] Pain, unspecified --PARENT--> [?] Pain --CHILD--> [MG30] Chronic pain Def: Pain is an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. Chronic pain is pain that persists or recurs for longer t... --- Walk 5 --- [8E43.Z] Pain disorders, unspecified --PARENT--> [8E43] Pain disorders --CHILD--> [8E43.0] Neuropathic pain Def: Neuropathic pain is described as electric, burning, or shock like, caused by metabolic, nutritional, infectious, genetic, autoimmune, and/or vasculitic processes. The pain may occur spontaneously, wit... --- Walk 6 --- [8E43.Z] Pain disorders, unspecified --PARENT--> [8E43] Pain disorders --CHILD--> [8E43.0] Neuropathic pain Def: Neuropathic pain is described as electric, burning, or shock like, caused by metabolic, nutritional, infectious, genetic, autoimmune, and/or vasculitic processes. The pain may occur spontaneously, wit...	[ "[PL11.5] Procedure undertaken at wrong site or wrong side, as mode of injury or harm\n --PARENT--> [PL11] Mode of injury or harm associated with a surgical or other medical procedure\n --PARENT--> [?] Causes of healthcare related harm or injury", "[PL11.5] Procedure undertaken at wrong site or wrong side, as mode of injury or harm\n --EXCLUDES--> [?] Patient received diagnostic test or treatment intended for another patient\n --EXCLUDES--> [?] Procedure undertaken at wrong site or wrong side, as mode of injury or harm", "[MG3Z] Pain, unspecified\n --PARENT--> [?] Pain\n --CHILD--> [MG31] Acute pain\n Def: Pain with a duration of less than 3 months.\n\nThis code should be used only when there is no further specification of site....", "[MG3Z] Pain, unspecified\n --PARENT--> [?] Pain\n --CHILD--> [MG30] Chronic pain\n Def: Pain is an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. Chronic pain is pain that persists or recurs for longer t...", "[8E43.Z] Pain disorders, unspecified\n --PARENT--> [8E43] Pain disorders\n --CHILD--> [8E43.0] Neuropathic pain\n Def: Neuropathic pain is described as electric, burning, or shock like, caused by metabolic, nutritional, infectious, genetic, autoimmune, and/or vasculitic processes. The pain may occur spontaneously, wit...", "[8E43.Z] Pain disorders, unspecified\n --PARENT--> [8E43] Pain disorders\n --CHILD--> [8E43.0] Neuropathic pain\n Def: Neuropathic pain is described as electric, burning, or shock like, caused by metabolic, nutritional, infectious, genetic, autoimmune, and/or vasculitic processes. The pain may occur spontaneously, wit..." ]	PL11.5	Procedure undertaken at wrong site or wrong side, as mode of injury or harm	[ { "from_icd11": "PL11.5", "icd10_code": "Y6551", "icd10_title": "Performance of wrong procedure (operation) on correct patient" }, { "from_icd11": "PL11.5", "icd10_code": "Y6553", "icd10_title": "Performance of correct procedure (operation) on wrong side or body part" }, { "from_icd11": "PL11.5", "icd10_code": "Y655", "icd10_title": "Performance of wrong procedure (operation)" }, { "from_icd11": "MG3Z", "icd10_code": "R52", "icd10_title": "Pain, unspecified" }, { "from_icd11": "MG3Z", "icd10_code": "R529", "icd10_title": "" }, { "from_icd11": "MG31.Z", "icd10_code": "R520", "icd10_title": "" }, { "from_icd11": "MG30.Z", "icd10_code": "R521", "icd10_title": "" }, { "from_icd11": "MG30.Z", "icd10_code": "R522", "icd10_title": "" }, { "from_icd11": "FB56.2", "icd10_code": "M7918", "icd10_title": "Myalgia, other site" }, { "from_icd11": "FB56.2", "icd10_code": "M7910", "icd10_title": "Myalgia, unspecified site" }, { "from_icd11": "FB56.2", "icd10_code": "M7912", "icd10_title": "Myalgia of auxiliary muscles, head and neck" }, { "from_icd11": "FB56.2", "icd10_code": "M791", "icd10_title": "Myalgia" }, { "from_icd11": "1F45", "icd10_code": "B54", "icd10_title": "Unspecified malaria" }, { "from_icd11": "1C41", "icd10_code": "A4902", "icd10_title": "Methicillin resistant Staphylococcus aureus infection, unspecified site" }, { "from_icd11": "1C41", "icd10_code": "A4901", "icd10_title": "Methicillin susceptible Staphylococcus aureus infection, unspecified site" } ]	Y6551	Performance of wrong procedure (operation) on correct patient
The side effects of ketamine abuse or misuse are commonly seen. In our case, the patient was diagnosed with autoimmune hepatitis, chronic cholecystitis, cholangitis and renal failure . It is unknown why he first presented with neurological symptoms from the weakness of the lower limbs, numbness, sensory disorder and decreased muscle strength. He then repeatedly convulsed, suddenly lost the ability to speak and died of brain dysfunction. Symptoms, such as weakness of the lower limbs and aphasia ( 26 , 27 ), indicate brain damage or brain functioning zone damage, but his brain atrophy may not be the same as common degeneration ( 28 ) which is associated with ageing. No signs of intracranial infection or any other brain disease were detected on CSF tests, such as cerebral infarction from the CT scans, except atrophy. However, a patient with status epilepticus reportedly also developed brain atrophy and some similar neurological symptoms after using ketamine ( 29 ). Therefore, it is likely that brain atrophy is a side-effect of chronic ketamine use. However, because ketamine is a dissociative drug, it is trivial for physicians to determine that a patient may appear with neuropsychiatric symptoms while overlooking a brain image to check whether any degenerative brain changes are occurring at the same time. This could be due to the few reports of brain atrophy associated with ketamine usage ( 24 , 25 ) .	4.082031	0.553711	sec[2]/p[1]	en	0.999996	34658951	https://doi.org/10.3389/fpsyt.2021.707326	[ "brain", "ketamine", "atrophy", "side", "neurological", "weakness", "limbs", "damage", "associated", "however" ]	[ { "code": "8E7Y", "title": "Other specified diseases of the nervous system" }, { "code": "LA05.Z", "title": "Cerebral structural developmental anomalies, unspecified" }, { "code": "1D00.Z", "title": "Infectious encephalitis, unspecified" }, { "code": "LA00.0Z", "title": "Anencephaly, unspecified" }, { "code": "NA07.3Y", "title": "Other specified diffuse brain injury" }, { "code": "NE60", "title": "Harmful effects of drugs, medicaments or biological substances, not elsewhere classified" }, { "code": "PB21&XM7C11", "title": "Unintentional exposure to or harmful effects of ketamine" }, { "code": "PC91&XM7C11", "title": "Intentional self-harm by exposure to or harmful effects of ketamine" }, { "code": "6C4D.2Z", "title": "Dissociative drug dependence including ketamine or PCP, unspecified" }, { "code": "6C4D.3", "title": "Dissociative drug intoxication including Ketamine or PCP" } ]	=== ICD-11 CODES FOUND === [8E7Y] Other specified diseases of the nervous system Also known as: Other specified diseases of the nervous system \| Circumscribed brain atrophy \| circumscribed cerebral atrophy \| atrophic lobar sclerosis \| atrophic lobar brain sclerosis [LA05.Z] Cerebral structural developmental anomalies, unspecified Also known as: Cerebral structural developmental anomalies, unspecified \| Cerebral structural developmental anomalies \| Malformations of brain \| brain abnormality NOS \| brain deformity NOS [1D00.Z] Infectious encephalitis, unspecified Also known as: Infectious encephalitis, unspecified \| Infectious encephalitis, not elsewhere classified \| encephalitis NOS \| acute encephalitis NOS \| acute brain inflammation [LA00.0Z] Anencephaly, unspecified Also known as: Anencephaly, unspecified \| Anencephaly \| anencephalic monster \| anencephalus \| brain absence [NA07.3Y] Other specified diffuse brain injury Also known as: Other specified diffuse brain injury \| Brain contusion \| Cerebral contusion NOS \| Diffuse cortex contusion \| diffuse cortical contusion [NE60] Harmful effects of drugs, medicaments or biological substances, not elsewhere classified Also known as: Harmful effects of drugs, medicaments or biological substances, not elsewhere classified \| drugs, medicaments or biological substances, toxicity not elsewhere classified \| adverse drug effects \| drug reaction NOS \| drug allergy NOS Excludes: Alcohol intoxication \| pathological drug intoxication \| hypersensitivity reaction to correctly administered drug [6C4D.2Z] Dissociative drug dependence including ketamine or PCP, unspecified Also known as: Dissociative drug dependence including ketamine or PCP, unspecified \| Dissociative drug dependence including ketamine or PCP \| Dissociative drug addiction including ketamine or PCP [6C4D.3] Dissociative drug intoxication including Ketamine or PCP Definition: Dissociative drug intoxication including Ketamine and PCP is a clinically significant transient condition that develops during or shortly after the consumption of a dissociative drug that is characterised by disturbances in consciousness, cognition, perception, affect, behaviour, or coordination. These disturbances are caused by the known pharmacological effects of a dissociative drug and their intensity is closely related to the amount of the dissociative drug consumed. They are time-limited an Also known as: Dissociative drug intoxication including Ketamine or PCP \| PCP intoxication \| phencyclidine intoxication === GRAPH WALKS === --- Walk 1 --- [8E7Y] Other specified diseases of the nervous system --PARENT--> [08] Diseases of the nervous system Def: This is a group of conditions characterised as being in or associated with the nervous system.... --EXCLUDES--> [?] Certain conditions originating in the perinatal period Def: This chapter includes conditions that have their origin in the perinatal period even though death or morbidity occurs later.... --- Walk 2 --- [8E7Y] Other specified diseases of the nervous system --PARENT--> [08] Diseases of the nervous system Def: This is a group of conditions characterised as being in or associated with the nervous system.... --EXCLUDES--> [?] Pregnancy, childbirth or the puerperium Def: A group of conditions characterised as occurring during the period of time from conception to delivery (pregnancy), during labour and delivery (childbirth) or during the approximately six weeks after ... --- Walk 3 --- [LA05.Z] Cerebral structural developmental anomalies, unspecified --PARENT--> [LA05] Cerebral structural developmental anomalies Def: Any condition caused by failure of the brain to correctly develop during the antenatal period.... --EXCLUDES--> [?] Encephalocele --- Walk 4 --- [LA05.Z] Cerebral structural developmental anomalies, unspecified --PARENT--> [LA05] Cerebral structural developmental anomalies Def: Any condition caused by failure of the brain to correctly develop during the antenatal period.... --CHILD--> [LA05.2] Holoprosencephaly Def: Holoprosencephaly is a brain malformation resulting from incomplete cleavage of the prosencephalon, occurring between the 18th and the 28th day of gestation and affecting both the forebrain and the fa... --- Walk 5 --- [1D00.Z] Infectious encephalitis, unspecified --PARENT--> [1D00] Infectious encephalitis, not elsewhere classified Def: A disease of the brain, caused by an infection.... --CHILD--> [1D00.0] Bacterial encephalitis --- Walk 6 --- [1D00.Z] Infectious encephalitis, unspecified --PARENT--> [1D00] Infectious encephalitis, not elsewhere classified Def: A disease of the brain, caused by an infection.... --CHILD--> [1D00.2] Parasitic or protozoal encephalitis Def: A disease of the brain, caused by an infection with a parasitic or protozoal source....	[ "[8E7Y] Other specified diseases of the nervous system\n --PARENT--> [08] Diseases of the nervous system\n Def: This is a group of conditions characterised as being in or associated with the nervous system....\n --EXCLUDES--> [?] Certain conditions originating in the perinatal period\n Def: This chapter includes conditions that have their origin in the perinatal period even though death or morbidity occurs later....", "[8E7Y] Other specified diseases of the nervous system\n --PARENT--> [08] Diseases of the nervous system\n Def: This is a group of conditions characterised as being in or associated with the nervous system....\n --EXCLUDES--> [?] Pregnancy, childbirth or the puerperium\n Def: A group of conditions characterised as occurring during the period of time from conception to delivery (pregnancy), during labour and delivery (childbirth) or during the approximately six weeks after ...", "[LA05.Z] Cerebral structural developmental anomalies, unspecified\n --PARENT--> [LA05] Cerebral structural developmental anomalies\n Def: Any condition caused by failure of the brain to correctly develop during the antenatal period....\n --EXCLUDES--> [?] Encephalocele", "[LA05.Z] Cerebral structural developmental anomalies, unspecified\n --PARENT--> [LA05] Cerebral structural developmental anomalies\n Def: Any condition caused by failure of the brain to correctly develop during the antenatal period....\n --CHILD--> [LA05.2] Holoprosencephaly\n Def: Holoprosencephaly is a brain malformation resulting from incomplete cleavage of the prosencephalon, occurring between the 18th and the 28th day of gestation and affecting both the forebrain and the fa...", "[1D00.Z] Infectious encephalitis, unspecified\n --PARENT--> [1D00] Infectious encephalitis, not elsewhere classified\n Def: A disease of the brain, caused by an infection....\n --CHILD--> [1D00.0] Bacterial encephalitis", "[1D00.Z] Infectious encephalitis, unspecified\n --PARENT--> [1D00] Infectious encephalitis, not elsewhere classified\n Def: A disease of the brain, caused by an infection....\n --CHILD--> [1D00.2] Parasitic or protozoal encephalitis\n Def: A disease of the brain, caused by an infection with a parasitic or protozoal source...." ]	8E7Y	Other specified diseases of the nervous system	[ { "from_icd11": "LA05.Z", "icd10_code": "Q048", "icd10_title": "Other specified congenital malformations of brain" }, { "from_icd11": "LA05.Z", "icd10_code": "Q043", "icd10_title": "Other reduction deformities of brain" }, { "from_icd11": "LA05.Z", "icd10_code": "Q049", "icd10_title": "Congenital malformation of brain, unspecified" }, { "from_icd11": "LA05.Z", "icd10_code": "Q04", "icd10_title": "Other congenital malformations of brain" }, { "from_icd11": "1D00.Z", "icd10_code": "G0490", "icd10_title": "Encephalitis and encephalomyelitis, unspecified" }, { "from_icd11": "1D00.Z", "icd10_code": "G0491", "icd10_title": "Myelitis, unspecified" }, { "from_icd11": "1D00.Z", "icd10_code": "G0430", "icd10_title": "Acute necrotizing hemorrhagic encephalopathy, unspecified" }, { "from_icd11": "1D00.Z", "icd10_code": "G0431", "icd10_title": "Postinfectious acute necrotizing hemorrhagic encephalopathy" }, { "from_icd11": "1D00.Z", "icd10_code": "G0439", "icd10_title": "Other acute necrotizing hemorrhagic encephalopathy" }, { "from_icd11": "1D00.Z", "icd10_code": "G0481", "icd10_title": "Other encephalitis and encephalomyelitis" }, { "from_icd11": "1D00.Z", "icd10_code": "G0489", "icd10_title": "Other myelitis" }, { "from_icd11": "1D00.Z", "icd10_code": "G04", "icd10_title": "Encephalitis, myelitis and encephalomyelitis" }, { "from_icd11": "1D00.Z", "icd10_code": "G048", "icd10_title": "Other encephalitis, myelitis and encephalomyelitis" }, { "from_icd11": "LA00.0Z", "icd10_code": "Q000", "icd10_title": "Anencephaly" }, { "from_icd11": "NE60", "icd10_code": "T50A95A", "icd10_title": "Adverse effect of other bacterial vaccines, initial encounter" } ]	Q048	Other specified congenital malformations of brain
A 43-year-old woman was admitted to the emergency department with acute respiratory failure and hypotension 13 hours after oral consumption of 300 mL of phoxim pesticide. She had no history of heart disease. The physical examination on admission showed the following: temperature, 36.8°C; heart rate, 84 beats/min; respiratory rate, 17 beats/min; and blood pressure, 81/42 mm Hg (norepinephrine, 0.2 μg/kg/min). She had clear consciousness, the pupils on both sides were equal and 3.5 mm in diameter, the skin was dry all over the body, there were no wet rales over both lungs on pulmonary auscultation, and there was no murmur on heart auscultation. The arterial blood gas analysis and myocardial enzyme spectrum were normal, while electrocardiography (ECG) showed sinus tachycardia on admission, and admission echocardiography showed that the motion of each segment of the left ventricular wall declined diffusely, and the left ventricular ejection fraction was 35%. Bedside chest X-ray (CXR) revealed abnormal density of both lungs, considering pulmonary edema or changes after poisoning. After admission, the patient was intubated and mechanically ventilated, analgesia and sedation were administered, rapid fluid expansion combined with norepinephrine was administered as an anti-shock treatment, hemoperfusion was performed, and atropine was administered to reverse the inhibitory effects of AOPP on cholinesterase.	3.892578	0.981445	sec[1]/p[0]	en	0.999998	34115044	https://doi.org/10.1097/MD.0000000000026318	[ "heart", "both", "respiratory", "beats", "blood", "norepinephrine", "over", "lungs", "pulmonary", "auscultation" ]	[ { "code": "BE2Y", "title": "Other specified diseases of the circulatory system" }, { "code": "BC4Z", "title": "Diseases of the myocardium or cardiac chambers, unspecified" }, { "code": "BD1Z", "title": "Heart failure, unspecified" }, { "code": "LA8Z", "title": "Structural developmental anomaly of heart or great vessels, unspecified" }, { "code": "BA41.Z", "title": "Acute myocardial infarction, unspecified" }, { "code": "LB99.6", "title": "Acheiria" }, { "code": "MB51.Z", "title": "Diplegia of upper extremities, unspecified" }, { "code": "LB9A.4", "title": "Apodia" }, { "code": "LB51", "title": "Anorchia or microorchidia" }, { "code": "9D90.2", "title": "Moderate vision impairment" } ]	=== ICD-11 CODES FOUND === [BE2Y] Other specified diseases of the circulatory system Also known as: Other specified diseases of the circulatory system \| Certain specified forms of heart disease \| Cardiac disorder, unspecified \| disorder of heart NOS \| organic disease or disorder of heart [BC4Z] Diseases of the myocardium or cardiac chambers, unspecified Also known as: Diseases of the myocardium or cardiac chambers, unspecified \| Heart disease NOS \| cardiac disease NOS [BD1Z] Heart failure, unspecified Also known as: Heart failure, unspecified \| myocardial failure \| cardiac decompensation \| cardiac failure \| cardiac failure NOS [LA8Z] Structural developmental anomaly of heart or great vessels, unspecified Also known as: Structural developmental anomaly of heart or great vessels, unspecified \| Heart malformations \| Cardiac malformations \| congenital anomaly of heart \| congenital heart disease [BA41.Z] Acute myocardial infarction, unspecified Also known as: Acute myocardial infarction, unspecified \| Acute myocardial infarction \| cardiac attack \| heart attack \| acute cardiac infarction [LB99.6] Acheiria Definition: A condition caused by failure of one or both hands to develop during the antenatal period. Also known as: Acheiria \| Congenital absence of hand \| agenesis of hand \| congenital absence of hand and finger \| congenital absence of hand and wrist [MB51.Z] Diplegia of upper extremities, unspecified Also known as: Diplegia of upper extremities, unspecified \| Diplegia of upper extremities \| paralysis of both upper limbs \| both upper extremity paralysis \| diplegia of upper limbs [LB9A.4] Apodia Definition: A condition caused by failure of the foot to develop during the antenatal period. Also known as: Apodia \| Congenital absence of foot \| agenesis of foot \| congenital absence of foot or toe \| congenital absence of foot or toe, unspecified side [LB51] Anorchia or microorchidia Definition: A disorder affecting males, caused by an abnormality occurring in sex development during the antenatal period. This disorder is characterised by individuals who are born with absence of the testes, or with testes that are deficient in size and function. Confirmation is by physical examination, identification of low testosterone levels but elevated follicle stimulating hormone and luteinizing hormone levels in a blood sample, or imaging. Also known as: Anorchia or microorchidia \| Absence or aplasia of testis, unilateral \| congenital absence of testis, unilateral \| congenital absent testicle \| congenital absence of testis [9D90.2] Moderate vision impairment Also known as: Moderate vision impairment \| low vision, both eyes \| visual impairment category 2, in both eyes \| Low vision \| LW - [low vision] Includes: visual impairment category 2, in both eyes === GRAPH WALKS === --- Walk 1 --- [BE2Y] Other specified diseases of the circulatory system --PARENT--> [11] Diseases of the circulatory system Def: This refers to diseases of the organ system that passes nutrients (such as amino acids, electrolytes and lymph), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases... --EXCLUDES--> [?] Certain infectious or parasitic diseases Def: This chapter includes certain conditions caused by pathogenic organisms or microorganisms, such as bacteria, viruses, parasites or fungi.... --- Walk 2 --- [BE2Y] Other specified diseases of the circulatory system --PARENT--> [11] Diseases of the circulatory system Def: This refers to diseases of the organ system that passes nutrients (such as amino acids, electrolytes and lymph), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases... --RELATED_TO--> [?] Symptoms, signs or clinical findings of the circulatory system --- Walk 3 --- [BC4Z] Diseases of the myocardium or cardiac chambers, unspecified --PARENT--> [?] Diseases of the myocardium or cardiac chambers Def: This refers to diseases of a type of involuntary striated muscle found in the walls and histological foundation of the heart, with specific reference to the atrial and ventricular chambers, as well as... --CHILD--> [BC41] Acquired ventricular abnormality Def: A postnatal pathological change in form or function of a ventricle.... --- Walk 4 --- [BC4Z] Diseases of the myocardium or cardiac chambers, unspecified --PARENT--> [?] Diseases of the myocardium or cardiac chambers Def: This refers to diseases of a type of involuntary striated muscle found in the walls and histological foundation of the heart, with specific reference to the atrial and ventricular chambers, as well as... --PARENT--> [11] Diseases of the circulatory system Def: This refers to diseases of the organ system that passes nutrients (such as amino acids, electrolytes and lymph), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases... --- Walk 5 --- [BD1Z] Heart failure, unspecified --PARENT--> [?] Heart failure --CHILD--> [BD12] High output syndromes Def: Increased cardiac output above normal associated with anaemia, arteriovenous fistulas, thyrotoxicosis and other syndromes. May result in heart failure.... --- Walk 6 --- [BD1Z] Heart failure, unspecified --PARENT--> [?] Heart failure --EXCLUDES--> [?] Other complications of obstetric surgery or procedures Def: Any complication caused by or subsequent to obstetric surgery and procedures, and not elsewhere classified....	[ "[BE2Y] Other specified diseases of the circulatory system\n --PARENT--> [11] Diseases of the circulatory system\n Def: This refers to diseases of the organ system that passes nutrients (such as amino acids, electrolytes and lymph), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases...\n --EXCLUDES--> [?] Certain infectious or parasitic diseases\n Def: This chapter includes certain conditions caused by pathogenic organisms or microorganisms, such as bacteria, viruses, parasites or fungi....", "[BE2Y] Other specified diseases of the circulatory system\n --PARENT--> [11] Diseases of the circulatory system\n Def: This refers to diseases of the organ system that passes nutrients (such as amino acids, electrolytes and lymph), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases...\n --RELATED_TO--> [?] Symptoms, signs or clinical findings of the circulatory system", "[BC4Z] Diseases of the myocardium or cardiac chambers, unspecified\n --PARENT--> [?] Diseases of the myocardium or cardiac chambers\n Def: This refers to diseases of a type of involuntary striated muscle found in the walls and histological foundation of the heart, with specific reference to the atrial and ventricular chambers, as well as...\n --CHILD--> [BC41] Acquired ventricular abnormality\n Def: A postnatal pathological change in form or function of a ventricle....", "[BC4Z] Diseases of the myocardium or cardiac chambers, unspecified\n --PARENT--> [?] Diseases of the myocardium or cardiac chambers\n Def: This refers to diseases of a type of involuntary striated muscle found in the walls and histological foundation of the heart, with specific reference to the atrial and ventricular chambers, as well as...\n --PARENT--> [11] Diseases of the circulatory system\n Def: This refers to diseases of the organ system that passes nutrients (such as amino acids, electrolytes and lymph), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases...", "[BD1Z] Heart failure, unspecified\n --PARENT--> [?] Heart failure\n --CHILD--> [BD12] High output syndromes\n Def: Increased cardiac output above normal associated with anaemia, arteriovenous fistulas, thyrotoxicosis and other syndromes. May result in heart failure....", "[BD1Z] Heart failure, unspecified\n --PARENT--> [?] Heart failure\n --EXCLUDES--> [?] Other complications of obstetric surgery or procedures\n Def: Any complication caused by or subsequent to obstetric surgery and procedures, and not elsewhere classified...." ]	BE2Y	Other specified diseases of the circulatory system	[ { "from_icd11": "BC4Z", "icd10_code": "I5181", "icd10_title": "Takotsubo syndrome" }, { "from_icd11": "BC4Z", "icd10_code": "I5189", "icd10_title": "Other ill-defined heart diseases" }, { "from_icd11": "BC4Z", "icd10_code": "I519", "icd10_title": "Heart disease, unspecified" }, { "from_icd11": "BC4Z", "icd10_code": "I510", "icd10_title": "Cardiac septal defect, acquired" }, { "from_icd11": "BC4Z", "icd10_code": "I515", "icd10_title": "Myocardial degeneration" }, { "from_icd11": "BC4Z", "icd10_code": "I51", "icd10_title": "Complications and ill-defined descriptions of heart disease" }, { "from_icd11": "BC4Z", "icd10_code": "I516", "icd10_title": "" }, { "from_icd11": "BC4Z", "icd10_code": "I518", "icd10_title": "Other ill-defined heart diseases" }, { "from_icd11": "BD1Z", "icd10_code": "I5023", "icd10_title": "Acute on chronic systolic (congestive) heart failure" }, { "from_icd11": "BD1Z", "icd10_code": "I5030", "icd10_title": "Unspecified diastolic (congestive) heart failure" }, { "from_icd11": "BD1Z", "icd10_code": "I5031", "icd10_title": "Acute diastolic (congestive) heart failure" }, { "from_icd11": "BD1Z", "icd10_code": "I5022", "icd10_title": "Chronic systolic (congestive) heart failure" }, { "from_icd11": "BD1Z", "icd10_code": "I5084", "icd10_title": "End stage heart failure" }, { "from_icd11": "BD1Z", "icd10_code": "I5020", "icd10_title": "Unspecified systolic (congestive) heart failure" }, { "from_icd11": "BD1Z", "icd10_code": "I5021", "icd10_title": "Acute systolic (congestive) heart failure" } ]	I5181	Takotsubo syndrome
The patient was initially diagnosed with Castleman disease two years ago via an axillary lymph node biopsy and was offered chemotherapy but declined for concern of side effects and financial burden. A bone marrow biopsy later revealed a hypocellular marrow at 40%. After a careful review amongst a multidisciplinary specialty tumor board, the patient was subsequently diagnosed with POEMS syndrome. At the time of diagnosis, the patient met diagnostic criteria which included: progressive neuropathy, elevated VEGF at 304 pg/mL (reference range: 31-86 pg/mL), splenomegaly at 186.8 millimeters (mm) (reference range: 76-131 mm), left para-aortic lymph node measuring 2.3 centimeters (cm) (reference range: 1.1 cm), left iliac chain lymph node measuring 2.7 cm (reference range: 0.7 cm), 2+ pitting edema bilaterally and bilateral foot skin ulcerations . Urine protein electrophoresis (UPEP) results indicated a monoclonal spike (M-spike) but was negligible to quantify (urine protein electrophoresis/urine immunofixation electrophoresis {UPEP/UIFE}: k/L 526/147 = 3.58). Serum protein electrophoresis (SPEP) results did not indicate an M-spike (serum protein electrophoresis/serum immunofixation electrophoresis {SPEP/SIFE}: k/L 78.2/71.2 = 1.09). Hematology recommended starting dexamethasone and lenalidomide (Revlimid) while waiting for stem cell transplant. Unfortunately, the patient again refused further treatment.	3.917969	0.979492	sec[1]/p[1]	en	0.999998	34692278	https://doi.org/10.7759/cureus.18046	[ "electrophoresis", "reference", "range", "protein", "lymph", "node", "urine", "spike", "serum", "diagnosed" ]	[ { "code": "6B22.Z", "title": "Olfactory reference disorder, unspecified" }, { "code": "MB26.03", "title": "Delusion of reference" }, { "code": "6B22.1", "title": "Olfactory reference disorder with poor to absent insight" }, { "code": "4B00.0Z", "title": "Neutropaenia, unspecified" }, { "code": "3B63.1Z", "title": "Acquired thrombocytosis, unspecified" }, { "code": "QA00.6Y", "title": "Other specified examination of eyes or vision" }, { "code": "MA14.1C", "title": "Raised antibody titre" }, { "code": "BD11.1", "title": "Left ventricular failure with mid range ejection fraction" }, { "code": "5B71", "title": "Protein deficiency" }, { "code": "5B7Z", "title": "Unspecified undernutrition" } ]	=== ICD-11 CODES FOUND === [6B22.Z] Olfactory reference disorder, unspecified Also known as: Olfactory reference disorder, unspecified \| Olfactory reference disorder \| Delusions of malodour [MB26.03] Delusion of reference Definition: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature. Also known as: Delusion of reference [6B22.1] Olfactory reference disorder with poor to absent insight Definition: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative explanation for their experience. The lack of insight exhibited by the individual does not vary markedly as a function of anxiety level. Also known as: Olfactory reference disorder with poor to absent insight [4B00.0Z] Neutropaenia, unspecified Also known as: Neutropaenia, unspecified \| Neutropenia \| Disorders with decreased neutrophil counts \| neutropaenic disorder \| neutrophil count below reference range [3B63.1Z] Acquired thrombocytosis, unspecified Also known as: Acquired thrombocytosis, unspecified \| Acquired thrombocytosis \| Idiopathic haemorrhagic thrombocythaemia \| Essential thrombocythaemia \| primary haemorrhagic thrombocythaemia [QA00.6Y] Other specified examination of eyes or vision Also known as: Other specified examination of eyes or vision \| No Impairment of Contrast vision \| Normal colour vision \| No Impairment of Dark adaptation \| No diplopia [MA14.1C] Raised antibody titre Also known as: Raised antibody titre \| antibody titre above reference range \| high antibody titre \| increased antibody titre Excludes: isoimmunization, in pregnancy affecting fetus or newborn [BD11.1] Left ventricular failure with mid range ejection fraction Also known as: Left ventricular failure with mid range ejection fraction \| HFmEF - [heart failure with mid range ejection fraction] \| Left ventricular failure with mid range ejection fraction due to cardiomyopathy \| Left ventricular failure with mid range ejection fraction due to coronary artery disease \| Left ventricular failure with mid range ejection fraction due to myocarditis [5B71] Protein deficiency Also known as: Protein deficiency \| protein deprivation [5B7Z] Unspecified undernutrition Also known as: Unspecified undernutrition \| Malnutrition NOS \| nutritional deficiency NOS \| nutritional depletion NOS \| severe malnutrition NOS === GRAPH WALKS === --- Walk 1 --- [6B22.Z] Olfactory reference disorder, unspecified --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --CHILD--> [6B22.Z] Olfactory reference disorder, unspecified --- Walk 2 --- [6B22.Z] Olfactory reference disorder, unspecified --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --CHILD--> [6B22.0] Olfactory reference disorder with fair to good insight Def: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true a... --- Walk 3 --- [MB26.03] Delusion of reference Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature.... --PARENT--> [MB26.0] Delusion Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus... --PARENT--> [MB26] Symptoms or signs involving content of thought Def: Symptoms and signs involving content of thought include delusions, experiences of influence, passivity, and control, grandiosity, homicidal ideation, identity disturbance, obsessions, overvalued ideas... --- Walk 4 --- [MB26.03] Delusion of reference Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature.... --PARENT--> [MB26.0] Delusion Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus... --CHILD--> [MB26.00] Bizarre delusion Def: A delusion that involves a phenomenon that would be regarded as physically impossible within the person's cultural context.... --- Walk 5 --- [6B22.1] Olfactory reference disorder with poor to absent insight Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative... --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --CHILD--> [6B22.0] Olfactory reference disorder with fair to good insight Def: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true a... --- Walk 6 --- [6B22.1] Olfactory reference disorder with poor to absent insight Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative... --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --CHILD--> [6B22.Z] Olfactory reference disorder, unspecified	[ "[6B22.Z] Olfactory reference disorder, unspecified\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --CHILD--> [6B22.Z] Olfactory reference disorder, unspecified", "[6B22.Z] Olfactory reference disorder, unspecified\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --CHILD--> [6B22.0] Olfactory reference disorder with fair to good insight\n Def: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true a...", "[MB26.03] Delusion of reference\n Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature....\n --PARENT--> [MB26.0] Delusion\n Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus...\n --PARENT--> [MB26] Symptoms or signs involving content of thought\n Def: Symptoms and signs involving content of thought include delusions, experiences of influence, passivity, and control, grandiosity, homicidal ideation, identity disturbance, obsessions, overvalued ideas...", "[MB26.03] Delusion of reference\n Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature....\n --PARENT--> [MB26.0] Delusion\n Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus...\n --CHILD--> [MB26.00] Bizarre delusion\n Def: A delusion that involves a phenomenon that would be regarded as physically impossible within the person's cultural context....", "[6B22.1] Olfactory reference disorder with poor to absent insight\n Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative...\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --CHILD--> [6B22.0] Olfactory reference disorder with fair to good insight\n Def: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true a...", "[6B22.1] Olfactory reference disorder with poor to absent insight\n Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative...\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --CHILD--> [6B22.Z] Olfactory reference disorder, unspecified" ]	6B22.Z	Olfactory reference disorder, unspecified	[ { "from_icd11": "6B22.Z", "icd10_code": "F428", "icd10_title": "Other obsessive-compulsive disorder" }, { "from_icd11": "3B63.1Z", "icd10_code": "D473", "icd10_title": "Essential (hemorrhagic) thrombocythemia" }, { "from_icd11": "MA14.1C", "icd10_code": "R760", "icd10_title": "Raised antibody titer" }, { "from_icd11": "5B71", "icd10_code": "E46", "icd10_title": "Unspecified protein-calorie malnutrition" }, { "from_icd11": "5B71", "icd10_code": "E440", "icd10_title": "Moderate protein-calorie malnutrition" }, { "from_icd11": "5B71", "icd10_code": "E441", "icd10_title": "Mild protein-calorie malnutrition" }, { "from_icd11": "5B71", "icd10_code": "E640", "icd10_title": "Sequelae of protein-calorie malnutrition" }, { "from_icd11": "5B71", "icd10_code": "E44", "icd10_title": "Protein-calorie malnutrition of moderate and mild degree" }, { "from_icd11": "5B71", "icd10_code": "E45", "icd10_title": "Retarded development following protein-calorie malnutrition" }, { "from_icd11": "5B7Z", "icd10_code": "E43", "icd10_title": "Unspecified severe protein-calorie malnutrition" }, { "from_icd11": "5B7Z", "icd10_code": "E538", "icd10_title": "Deficiency of other specified B group vitamins" }, { "from_icd11": "5B7Z", "icd10_code": "E569", "icd10_title": "Vitamin deficiency, unspecified" }, { "from_icd11": "5B7Z", "icd10_code": "E638", "icd10_title": "Other specified nutritional deficiencies" }, { "from_icd11": "5B7Z", "icd10_code": "E639", "icd10_title": "Nutritional deficiency, unspecified" }, { "from_icd11": "5B7Z", "icd10_code": "E41", "icd10_title": "Nutritional marasmus" } ]	F428	Other obsessive-compulsive disorder
Complete excision of hydatid cyst in the subcutaneous tissue can be an efficient surgical option, where all cysts are radically removed . The cyst must be removed completely and avoiding spilling its contents since hazardous anaphylaxis and dissemination have been reported . When radical removal is impossible, surgical treatment is not curative and recurrence is expected. In these cases, supplementary chemotherapy can be started. Antihelmintic drugs, such as mebendazole (50 mg/kg/daily) or albendazole (10 mg/kg/daily) are needed for 4 to 6 months . We have completely surgically excised the cyst; however, it had been ruptured in the operative field. Complete excision of hydatid cysts in the subcutaneous tissue, in which all cysts are radically eliminated, can be an effective surgical alternative . Because dangerous anaphylaxis and dispersion have been observed , the cyst must be fully excised while avoiding leaking its contents. Surgical treatment is not curative when radical excision is difficult, and recurrence is predicted. Supplementary chemotherapy can be started in these circumstances. For 4 to 6 months, antihelmintic medications such as mebendazole (50 mg/kg/day) or albendazole (10 mg/kg/day) are required . In our case, the cyst had been totally surgically removed, but it had ruptured in the operation field. Thus, the patient was discharged on a complete course of albendazole postoperatively.	4.046875	0.707031	sec[2]/p[1]	en	0.999997	PMC8831219	https://doi.org/10.11604/pamj.2021.40.246.32301	[ "cyst", "complete", "excision", "cysts", "albendazole", "hydatid", "subcutaneous", "tissue", "radically", "completely" ]	[ { "code": "FB80.5", "title": "Solitary bone cyst" }, { "code": "EK70.Z", "title": "Cutaneous cysts, unspecified" }, { "code": "FB4Y", "title": "Other specified disorders of synovium or tendon" }, { "code": "CA0C", "title": "Cyst or mucocele of nose or nasal sinus" }, { "code": "9A7Y", "title": "Other specified disorders of the cornea" }, { "code": "MB5Z", "title": "Paralytic symptoms, unspecified" }, { "code": "LB9B", "title": "Reduction defects of upper and lower limbs" }, { "code": "LA85.1", "title": "Transposition of the great arteries" }, { "code": "LD40.Y", "title": "Other specified complete trisomies of the autosomes" }, { "code": "9D90.6", "title": "Blindness" } ]	=== ICD-11 CODES FOUND === [FB80.5] Solitary bone cyst Definition: A solitary bone cyst is a benign non-epithelial bone cavity that is asymptomatic and that is found most commonly in the second decade of life by chance. The long bones are most often affected, but cases involving the jaw bone have been reported. Also known as: Solitary bone cyst \| cyst of bone \| local cyst of bone \| simple bone cyst \| solitary bone cyst, unspecified site Excludes: solitary cyst of jaw [EK70.Z] Cutaneous cysts, unspecified Also known as: Cutaneous cysts, unspecified \| Cutaneous cysts \| Follicular cysts of skin and subcutaneous tissue [FB4Y] Other specified disorders of synovium or tendon Also known as: Other specified disorders of synovium or tendon \| Shortening of tendon \| short tendon \| Shortening of tibialis anterior \| Contracture of tendon [CA0C] Cyst or mucocele of nose or nasal sinus Definition: A condition which refers to diseases of the nose and nasal sinus that cause a cyst or mucocele. A mucocele is any dilatation (typically pathologic) with accumulation of mucus. Mucoceles are benign, epithelium-lined cysts filled with mucus, which can form in the paranasal sinuses. These structures may cause symptoms if sufficiently large or if exerting pressure on surrounding anatomic structures. Symptomatic mucoceles typically require surgical intervention. Mucoceles should be differentiated fro Also known as: Cyst or mucocele of nose or nasal sinus \| cyst of sinus \| mucocele of sinus \| Cyst of maxillary sinus \| cyst of maxillary antrum [9A7Y] Other specified disorders of the cornea Also known as: Other specified disorders of the cornea \| Secondary disorders of sclera or cornea \| Disorders of sclera and cornea in diseases classified elsewhere \| Secondary keratitis or keratoconjunctivitis \| Keratitis and keratoconjunctivitis in other diseases classified elsewhere [MB5Z] Paralytic symptoms, unspecified Also known as: Paralytic symptoms, unspecified \| paralysis syndrome \| incomplete paralysis \| complete paralysis \| paresis [LB9B] Reduction defects of upper and lower limbs Also known as: Reduction defects of upper and lower limbs \| Tetraamelia \| Total amelia \| Split hand - split foot \| Acheiropodia [LA85.1] Transposition of the great arteries Definition: A congenital cardiovascular malformation in which the morphologically right ventricle or its remnant connects to the aorta and the morphologically left ventricle or its remnant connects to the pulmonary trunk. Also known as: Transposition of the great arteries \| Discordant ventriculoarterial connection \| complete transposition of great vessels \| great vessels complete transposition \| great vessels transposition [LD40.Y] Other specified complete trisomies of the autosomes Also known as: Other specified complete trisomies of the autosomes \| Other complete trisomies \| entire chromosome trisomy, meiotic nondisjunction \| Other trisomy mosaicism \| Whole chromosome trisomy, mosaicism disorder [9D90.6] Blindness Definition: The numerical definition used for WHO statistics refers to profound, near-total or total loss. The functional definition refers to individuals who have little or no residual vision and who have to rely predominantly on vision substitution skills, i.e. on using senses other than vision (Braille or talking books for reading, a long cane or guide dog for mobility, or touch for manipulation). Also known as: Blindness \| acquired amaurosis \| acquired blindness \| amaurosis \| blindness, both eyes Includes: visual impairment category 5 \| visual impairment categories 4, 5, 6 in both eyes \| visual impairment categories 4, 5, 6 in one eye and categories 1, 2, 3 or 9 in the other eye === GRAPH WALKS === --- Walk 1 --- [FB80.5] Solitary bone cyst Def: A solitary bone cyst is a benign non-epithelial bone cavity that is asymptomatic and that is found most commonly in the second decade of life by chance. The long bones are most often affected, but cas... --EXCLUDES--> [?] Other cysts of jaw Def: This is mostly odontogenic cysts but may be also of non-odontogenic source. The mandible and maxilla are the bones with the highest prevalent of cysts in the human body owing to odontogenic and develo... --EXCLUDES--> [?] Stafne mandibular bone cavity Def: Although commonly called a Stafne cyst, this entity is not a true cyst but rather a cavity due to a focal cortical defect of the medial aspect of the mandible. It is found most frequently in middle-ag... --- Walk 2 --- [FB80.5] Solitary bone cyst Def: A solitary bone cyst is a benign non-epithelial bone cavity that is asymptomatic and that is found most commonly in the second decade of life by chance. The long bones are most often affected, but cas... --EXCLUDES--> [?] Other cysts of jaw Def: This is mostly odontogenic cysts but may be also of non-odontogenic source. The mandible and maxilla are the bones with the highest prevalent of cysts in the human body owing to odontogenic and develo... --CHILD--> [?] Aneurysmal cyst of jaw --- Walk 3 --- [EK70.Z] Cutaneous cysts, unspecified --PARENT--> [EK70] Cutaneous cysts --CHILD--> [EK70.0] Epidermoid cyst Def: A cutaneous cyst with an epidermoid wall filled with keratin and its breakdown products. It most commonly forms as the result of squamous metaplasia in a damaged sebaceous gland but may result from tr... --- Walk 4 --- [EK70.Z] Cutaneous cysts, unspecified --PARENT--> [EK70] Cutaneous cysts --CHILD--> [EK70.2] Digital myxoid pseudocyst Def: Digital myxoid cysts (DMCs) are benign ganglion cysts of the digits, which typically present as a small dome-shaped, often translucent papule on the dorsum of the terminal phalanx and/or as longitudin... --- Walk 5 --- [FB4Y] Other specified disorders of synovium or tendon --PARENT--> [?] Disorders of synovium or tendon Def: This is a group of disorders which affect the synovial joint lining (synovium) and also tendons.... --CHILD--> [FB42] Certain specified disorders of synovium or tendon --- Walk 6 --- [FB4Y] Other specified disorders of synovium or tendon --PARENT--> [?] Disorders of synovium or tendon Def: This is a group of disorders which affect the synovial joint lining (synovium) and also tendons.... --CHILD--> [FB40] Tenosynovitis	[ "[FB80.5] Solitary bone cyst\n Def: A solitary bone cyst is a benign non-epithelial bone cavity that is asymptomatic and that is found most commonly in the second decade of life by chance. The long bones are most often affected, but cas...\n --EXCLUDES--> [?] Other cysts of jaw\n Def: This is mostly odontogenic cysts but may be also of non-odontogenic source. The mandible and maxilla are the bones with the highest prevalent of cysts in the human body owing to odontogenic and develo...\n --EXCLUDES--> [?] Stafne mandibular bone cavity\n Def: Although commonly called a Stafne cyst, this entity is not a true cyst but rather a cavity due to a focal cortical defect of the medial aspect of the mandible. It is found most frequently in middle-ag...", "[FB80.5] Solitary bone cyst\n Def: A solitary bone cyst is a benign non-epithelial bone cavity that is asymptomatic and that is found most commonly in the second decade of life by chance. The long bones are most often affected, but cas...\n --EXCLUDES--> [?] Other cysts of jaw\n Def: This is mostly odontogenic cysts but may be also of non-odontogenic source. The mandible and maxilla are the bones with the highest prevalent of cysts in the human body owing to odontogenic and develo...\n --CHILD--> [?] Aneurysmal cyst of jaw", "[EK70.Z] Cutaneous cysts, unspecified\n --PARENT--> [EK70] Cutaneous cysts\n --CHILD--> [EK70.0] Epidermoid cyst\n Def: A cutaneous cyst with an epidermoid wall filled with keratin and its breakdown products. It most commonly forms as the result of squamous metaplasia in a damaged sebaceous gland but may result from tr...", "[EK70.Z] Cutaneous cysts, unspecified\n --PARENT--> [EK70] Cutaneous cysts\n --CHILD--> [EK70.2] Digital myxoid pseudocyst\n Def: Digital myxoid cysts (DMCs) are benign ganglion cysts of the digits, which typically present as a small dome-shaped, often translucent papule on the dorsum of the terminal phalanx and/or as longitudin...", "[FB4Y] Other specified disorders of synovium or tendon\n --PARENT--> [?] Disorders of synovium or tendon\n Def: This is a group of disorders which affect the synovial joint lining (synovium) and also tendons....\n --CHILD--> [FB42] Certain specified disorders of synovium or tendon", "[FB4Y] Other specified disorders of synovium or tendon\n --PARENT--> [?] Disorders of synovium or tendon\n Def: This is a group of disorders which affect the synovial joint lining (synovium) and also tendons....\n --CHILD--> [FB40] Tenosynovitis" ]	FB80.5	Solitary bone cyst	[ { "from_icd11": "FB80.5", "icd10_code": "M85412", "icd10_title": "Solitary bone cyst, left shoulder" }, { "from_icd11": "FB80.5", "icd10_code": "M85441", "icd10_title": "Solitary bone cyst, right hand" }, { "from_icd11": "FB80.5", "icd10_code": "M8548", "icd10_title": "Solitary bone cyst, other site" }, { "from_icd11": "FB80.5", "icd10_code": "M8540", "icd10_title": "Solitary bone cyst, unspecified site" }, { "from_icd11": "FB80.5", "icd10_code": "M854", "icd10_title": "Solitary bone cyst" }, { "from_icd11": "EK70.Z", "icd10_code": "L729", "icd10_title": "Follicular cyst of the skin and subcutaneous tissue, unspecified" }, { "from_icd11": "EK70.Z", "icd10_code": "L728", "icd10_title": "Other follicular cysts of the skin and subcutaneous tissue" }, { "from_icd11": "EK70.Z", "icd10_code": "L60-L75", "icd10_title": "" }, { "from_icd11": "EK70.Z", "icd10_code": "L72", "icd10_title": "Follicular cysts of skin and subcutaneous tissue" }, { "from_icd11": "CA0C", "icd10_code": "J341", "icd10_title": "Cyst and mucocele of nose and nasal sinus" }, { "from_icd11": "MB5Z", "icd10_code": "G8384", "icd10_title": "Todd's paralysis (postepileptic)" }, { "from_icd11": "MB5Z", "icd10_code": "G8331", "icd10_title": "Monoplegia, unspecified affecting right dominant side" }, { "from_icd11": "MB5Z", "icd10_code": "G8389", "icd10_title": "Other specified paralytic syndromes" }, { "from_icd11": "MB5Z", "icd10_code": "G8383", "icd10_title": "Posterior cord syndrome" }, { "from_icd11": "MB5Z", "icd10_code": "G8381", "icd10_title": "Brown-Sequard syndrome" } ]	M85412	Solitary bone cyst, left shoulder
A 37‐year‐old home baker with no known medical illness presented with cough for 4 weeks with intermittent haemoptysis associated with left upper back pain and left pleuritic chest pain. There were no other symptoms such as fever, night sweats or shortness of breath. Clinically, she had clear lungs upon auscultation and no palpable lymph nodes. Spontaneous sputum AFB was negative. Erythrocyte sedimentation rate was raised at 80/h and Mantoux TST revealed 12 mm induration. Chest radiograph revealed left midzone cavity. CT thorax showed spiculated thick‐walled cavitating lesion at the left lower lobe, measuring 1.9 × 2.3 × 1.8 cm . The patient was then treated empirically as smear‐negative pulmonary TB (PTB) and bronchoscopy was done. However, BAL also did not show any evidence of TB as the Xpert® MTB/rifampicin assay and AFB were negative. Respiratory culture from BAL was also negative. Despite undergoing anti‐TB treatment for 1 month, the patient's symptoms persisted; hence, CT‐guided lung biopsy was done which showed the presence of Masson bodies consistent with OP. CTD screening was negative. The patient was started on tapering dose of oral prednisolone at 0.5 mg/kg and follow‐up radiograph a month later showed improvement. Her TB culture after 2 months was negative. At 6 months, air space opacity on chest x‐ray had resolved . As she was asymptomatic thereafter, she was discharged from our clinic.	3.787109	0.98584	sec[1]/sec[1]/p[0]	en	0.999996	34876988	https://doi.org/10.1002/rcr2.883	[ "chest", "pain", "radiograph", "culture", "home", "baker", "known", "illness", "cough", "intermittent" ]	[ { "code": "CB7Z", "title": "Diseases of the respiratory system, unspecified" }, { "code": "CB27", "title": "Pleural effusion" }, { "code": "CA44", "title": "Pyothorax" }, { "code": "MD30.Z", "title": "Chest pain, unspecified" }, { "code": "NA80.Y&XJ1C6", "title": "Thoracic haematoma" }, { "code": "MG3Z", "title": "Pain, unspecified" }, { "code": "8E43.Z", "title": "Pain disorders, unspecified" }, { "code": "MG31.Z", "title": "Acute pain, unspecified" }, { "code": "MG30.Z", "title": "Chronic pain, unspecified" }, { "code": "FB56.2", "title": "Myalgia" } ]	=== ICD-11 CODES FOUND === [CB7Z] Diseases of the respiratory system, unspecified Also known as: Diseases of the respiratory system, unspecified \| disorder of respiratory system \| respiratory disease NOS \| respiratory tract disease \| respiratory disorder NOS [CB27] Pleural effusion Definition: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. Also known as: Pleural effusion \| PE - [pleural effusion] \| Pleurisy with effusion \| pleurisy with effusion NOS \| pleural effusion with transudate Includes: Pleurisy with effusion Excludes: Tuberculosis of the respiratory system \| Chylous effusion \| Pleurisy [CA44] Pyothorax Definition: Suppurative inflammation of the pleural space, typically due to acute bacterial infection. It can occur as a complication of pneumonia, thoracotomy, abscesses (lung, hepatic, or subdiaphragmatic), or penetrating trauma with a secondary infection. Also known as: Pyothorax \| empyema \| pyopneumothorax \| Pyothorax with fistula \| empyema with fistula Includes: empyema \| pyopneumothorax Excludes: due to tuberculosis [MD30.Z] Chest pain, unspecified Also known as: Chest pain, unspecified \| Pain in throat or chest \| chest pain NOS \| pain in chest \| chest pressure [MG3Z] Pain, unspecified Also known as: Pain, unspecified \| pain observations \| pain NOS \| generalised pain \| generalised pain, NOS [8E43.Z] Pain disorders, unspecified Also known as: Pain disorders, unspecified \| Pain disorders [MG31.Z] Acute pain, unspecified Also known as: Acute pain, unspecified \| Acute pain [MG30.Z] Chronic pain, unspecified Also known as: Chronic pain, unspecified \| Chronic pain [FB56.2] Myalgia Definition: This is a disorder characterised by pain in a muscle or group of muscles. Also known as: Myalgia \| muscle ache \| muscle soreness \| muscular pain \| myalgic Excludes: Chronic primary musculoskeletal pain \| Chronic secondary musculoskeletal pain === GRAPH WALKS === --- Walk 1 --- [CB7Z] Diseases of the respiratory system, unspecified --PARENT--> [12] Diseases of the respiratory system --RELATED_TO--> [?] Symptoms, signs or clinical findings of the respiratory system --- Walk 2 --- [CB7Z] Diseases of the respiratory system, unspecified --PARENT--> [12] Diseases of the respiratory system --EXCLUDES--> [?] Developmental anomalies Def: This chapter includes conditions caused by failure of a particular body site or body system to develop correctly during the antenatal period.... --- Walk 3 --- [CB27] Pleural effusion Def: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces.... --EXCLUDES--> [?] Tuberculosis of the respiratory system Def: This is a progressive or chronic disease resulting from infection with the bacterium Mycobacterium tuberculosis or other bacteria in the M. tuberculosis complex: M. bovis, M. africanum, M. canetti, M.... --CHILD--> [?] Tuberculosis of lung, without mention of bacteriological or histological confirmation Def: This is a common, and in many cases lethal, infectious disease of the lung caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is without mention of bacteriol... --- Walk 4 --- [CB27] Pleural effusion Def: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces.... --EXCLUDES--> [?] Chylous effusion Def: A chylothorax (chylous effusion) signifies leakage of chyle from the thoracic duct. A pleural fluid triglyceride concentration of more than 110 mg per decilitre signifies a high likelihood of chylotho... --PARENT--> [?] Other pleural conditions Def: Any other condition effecting the thin serous membrane enveloping the lungs and lining the thoracic cavity... --- Walk 5 --- [CA44] Pyothorax Def: Suppurative inflammation of the pleural space, typically due to acute bacterial infection. It can occur as a complication of pneumonia, thoracotomy, abscesses (lung, hepatic, or subdiaphragmatic), or ... --EXCLUDES--> [?] Tuberculous pleurisy, without mention of bacteriological or histological confirmation Def: This is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis, with an inflammation of the pleura. This diagnosis is with... --EXCLUDES--> [?] Primary respiratory tuberculosis without mention of bacteriological or histological confirmation Def: This is a common, and in many cases lethal, infectious disease of the respiratory caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is without mention of ba... --- Walk 6 --- [CA44] Pyothorax Def: Suppurative inflammation of the pleural space, typically due to acute bacterial infection. It can occur as a complication of pneumonia, thoracotomy, abscesses (lung, hepatic, or subdiaphragmatic), or ... --EXCLUDES--> [?] Tuberculous pleurisy, without mention of bacteriological or histological confirmation Def: This is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis, with an inflammation of the pleura. This diagnosis is with... --EXCLUDES--> [?] Primary respiratory tuberculosis without mention of bacteriological or histological confirmation Def: This is a common, and in many cases lethal, infectious disease of the respiratory caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is without mention of ba...	[ "[CB7Z] Diseases of the respiratory system, unspecified\n --PARENT--> [12] Diseases of the respiratory system\n --RELATED_TO--> [?] Symptoms, signs or clinical findings of the respiratory system", "[CB7Z] Diseases of the respiratory system, unspecified\n --PARENT--> [12] Diseases of the respiratory system\n --EXCLUDES--> [?] Developmental anomalies\n Def: This chapter includes conditions caused by failure of a particular body site or body system to develop correctly during the antenatal period....", "[CB27] Pleural effusion\n Def: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces....\n --EXCLUDES--> [?] Tuberculosis of the respiratory system\n Def: This is a progressive or chronic disease resulting from infection with the bacterium Mycobacterium tuberculosis or other bacteria in the M. tuberculosis complex: M. bovis, M. africanum, M. canetti, M....\n --CHILD--> [?] Tuberculosis of lung, without mention of bacteriological or histological confirmation\n Def: This is a common, and in many cases lethal, infectious disease of the lung caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is without mention of bacteriol...", "[CB27] Pleural effusion\n Def: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces....\n --EXCLUDES--> [?] Chylous effusion\n Def: A chylothorax (chylous effusion) signifies leakage of chyle from the thoracic duct. A pleural fluid triglyceride concentration of more than 110 mg per decilitre signifies a high likelihood of chylotho...\n --PARENT--> [?] Other pleural conditions\n Def: Any other condition effecting the thin serous membrane enveloping the lungs and lining the thoracic cavity...", "[CA44] Pyothorax\n Def: Suppurative inflammation of the pleural space, typically due to acute bacterial infection. It can occur as a complication of pneumonia, thoracotomy, abscesses (lung, hepatic, or subdiaphragmatic), or ...\n --EXCLUDES--> [?] Tuberculous pleurisy, without mention of bacteriological or histological confirmation\n Def: This is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis, with an inflammation of the pleura. This diagnosis is with...\n --EXCLUDES--> [?] Primary respiratory tuberculosis without mention of bacteriological or histological confirmation\n Def: This is a common, and in many cases lethal, infectious disease of the respiratory caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is without mention of ba...", "[CA44] Pyothorax\n Def: Suppurative inflammation of the pleural space, typically due to acute bacterial infection. It can occur as a complication of pneumonia, thoracotomy, abscesses (lung, hepatic, or subdiaphragmatic), or ...\n --EXCLUDES--> [?] Tuberculous pleurisy, without mention of bacteriological or histological confirmation\n Def: This is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis, with an inflammation of the pleura. This diagnosis is with...\n --EXCLUDES--> [?] Primary respiratory tuberculosis without mention of bacteriological or histological confirmation\n Def: This is a common, and in many cases lethal, infectious disease of the respiratory caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is without mention of ba..." ]	CB7Z	Diseases of the respiratory system, unspecified	[ { "from_icd11": "CB7Z", "icd10_code": "J989", "icd10_title": "Respiratory disorder, unspecified" }, { "from_icd11": "CB7Z", "icd10_code": "X", "icd10_title": "" }, { "from_icd11": "CB7Z", "icd10_code": "J09-J18", "icd10_title": "" }, { "from_icd11": "CB27", "icd10_code": "J910", "icd10_title": "Malignant pleural effusion" }, { "from_icd11": "CB27", "icd10_code": "J918", "icd10_title": "Pleural effusion in other conditions classified elsewhere" }, { "from_icd11": "CB27", "icd10_code": "J90", "icd10_title": "Pleural effusion, not elsewhere classified" }, { "from_icd11": "CB27", "icd10_code": "J90-J94", "icd10_title": "" }, { "from_icd11": "CB27", "icd10_code": "J91", "icd10_title": "Pleural effusion in conditions classified elsewhere" }, { "from_icd11": "CA44", "icd10_code": "J869", "icd10_title": "Pyothorax without fistula" }, { "from_icd11": "CA44", "icd10_code": "J860", "icd10_title": "Pyothorax with fistula" }, { "from_icd11": "CA44", "icd10_code": "J85-J86", "icd10_title": "" }, { "from_icd11": "CA44", "icd10_code": "J86", "icd10_title": "Pyothorax" }, { "from_icd11": "MD30.Z", "icd10_code": "R0781", "icd10_title": "Pleurodynia" }, { "from_icd11": "MD30.Z", "icd10_code": "R0782", "icd10_title": "Intercostal pain" }, { "from_icd11": "MD30.Z", "icd10_code": "R079", "icd10_title": "Chest pain, unspecified" } ]	J989	Respiratory disorder, unspecified
An 88-year-old male presented prior to the initial description of VEXAS syndrome with right eye pain and vision changes associated with periorbital oedema. An MRI of the orbits demonstrated soft tissue swelling in the periorbital and maxillary regions with perineural enhancement of the right optic nerve sheath. Laboratory studies demonstrated the presence of mild macrocytic anaemia and elevated inflammatory markers (ESR 125 mm/h and CRP 14.8 mg/dl). The patient also had a history suggestive of relapsing polychondritis (RP), with features of a seronegative inflammatory arthritis and inflammation of the auricular cartilage. In addition to RP, a diagnosis of GPA was also considered, although ANCA serology testing was negative. Initial treatment was given in the form of methylprednisolone pulses followed by oral steroid taper and methotrexate. On follow-up, he demonstrated resolution in his periorbital swelling and eye pain, but macrocytosis was a persistent finding. Recurrence of arthralgia occurred with attempts to completely withdraw steroids. Subsequent to its reporting, VEXAS syndrome was considered as a unifying diagnosis and a Sanger sequencing–based test demonstrated the presence of a p.Met4Leu UBA1 mutation in peripheral blood. The patient’s course was characterized by symptomatic response to long-term, low-dose (5 mg) steroids. He later died from complications of a pre-existing heart failure.	4.039063	0.980469	sec[2]/sec[1]/p[0]	en	0.999999	39411287	https://doi.org/10.1093/rap/rkae116	[ "periorbital", "vexas", "pain", "swelling", "presence", "inflammatory", "considered", "steroids", "description", "vision" ]	[ { "code": "9A21.Z", "title": "Orbital infection, unspecified" }, { "code": "NE00&XA2WJ9", "title": "Burn of eye or ocular adnexa [Orbit]" }, { "code": "NE00&XA8E69", "title": "Burn of eye or ocular adnexa [Orbital bone]" }, { "code": "NE00&XA29E7", "title": "Burn of eye or ocular adnexa [Orbital region]" }, { "code": "NE00&XA0SB3", "title": "Burn of eye or ocular adnexa [Periorbital region]" }, { "code": "MG3Z", "title": "Pain, unspecified" }, { "code": "8E43.Z", "title": "Pain disorders, unspecified" }, { "code": "MG31.Z", "title": "Acute pain, unspecified" }, { "code": "MG30.Z", "title": "Chronic pain, unspecified" }, { "code": "FB56.2", "title": "Myalgia" } ]	=== ICD-11 CODES FOUND === [9A21.Z] Orbital infection, unspecified Also known as: Orbital infection, unspecified \| Orbital infection \| orbit infection \| periorbital infection [MG3Z] Pain, unspecified Also known as: Pain, unspecified \| pain observations \| pain NOS \| generalised pain \| generalised pain, NOS [8E43.Z] Pain disorders, unspecified Also known as: Pain disorders, unspecified \| Pain disorders [MG31.Z] Acute pain, unspecified Also known as: Acute pain, unspecified \| Acute pain [MG30.Z] Chronic pain, unspecified Also known as: Chronic pain, unspecified \| Chronic pain [FB56.2] Myalgia Definition: This is a disorder characterised by pain in a muscle or group of muscles. Also known as: Myalgia \| muscle ache \| muscle soreness \| muscular pain \| myalgic Excludes: Chronic primary musculoskeletal pain \| Chronic secondary musculoskeletal pain === GRAPH WALKS === --- Walk 1 --- [9A21.Z] Orbital infection, unspecified --PARENT--> [9A21] Orbital infection --RELATED_TO--> [?] Osteomyelitis of orbit --- Walk 2 --- [9A21.Z] Orbital infection, unspecified --PARENT--> [9A21] Orbital infection --RELATED_TO--> [?] Hydatic cyst	[ "[9A21.Z] Orbital infection, unspecified\n --PARENT--> [9A21] Orbital infection\n --RELATED_TO--> [?] Osteomyelitis of orbit", "[9A21.Z] Orbital infection, unspecified\n --PARENT--> [9A21] Orbital infection\n --RELATED_TO--> [?] Hydatic cyst" ]	9A21.Z	Orbital infection, unspecified	[ { "from_icd11": "MG3Z", "icd10_code": "R52", "icd10_title": "Pain, unspecified" }, { "from_icd11": "MG3Z", "icd10_code": "R529", "icd10_title": "" }, { "from_icd11": "MG31.Z", "icd10_code": "R520", "icd10_title": "" }, { "from_icd11": "MG30.Z", "icd10_code": "R521", "icd10_title": "" }, { "from_icd11": "MG30.Z", "icd10_code": "R522", "icd10_title": "" }, { "from_icd11": "FB56.2", "icd10_code": "M7918", "icd10_title": "Myalgia, other site" }, { "from_icd11": "FB56.2", "icd10_code": "M7910", "icd10_title": "Myalgia, unspecified site" }, { "from_icd11": "FB56.2", "icd10_code": "M7912", "icd10_title": "Myalgia of auxiliary muscles, head and neck" }, { "from_icd11": "FB56.2", "icd10_code": "M791", "icd10_title": "Myalgia" } ]	R52	Pain, unspecified
Open debridement of the adductors through a medial approach drained pus. Biopsies and blood cultures identified Staphylococcus aureus (methicillin-sensitive). Intravenous antibiotic treatment was started with amoxicillin-clavulanic acid 2200 mg followed one day later by intravenous flucloxacillin 2000 mg four times a day. Blood cultures taken 3 and 5 days postoperatively remained positive, which prompted a follow-up MRI that showed residual fluid collection within the right adductor compartment. Revision adductor debridement and additional debridement of the symphysis through a Pfannenstiel incision were performed. Biopsies identified S. aureus at the symphysis and adductors. Due to persisting wound drainage, a third look surgery of the adductor compartment followed 2 weeks later and subcutaneous seroma was drained. Four weeks after the first surgery, CRP was 23 mg/l, WBC count was normal, the wound was bland and the patient was able to ambulate with crutches. Before leaving the hospital the visual analog scale for pain was zero at rest and also when walking with crutches. He was discharged home with a 9-week course of oral clindamycin 600 mg three times daily. At four months follow-up there was no evidence of infection locally or systemically with a normal CRP level. There was no pain over the symphysis or the right adductor compartment and the patient used a cane but was able to walk without aid.	3.712891	0.979492	sec[1]/p[3]	en	0.999996	PMC8765581	https://doi.org/10.7759/cureus.21138	[ "adductor", "debridement", "four", "compartment", "symphysis", "adductors", "drained", "biopsies", "blood", "cultures" ]	[ { "code": "NC76.21", "title": "Laceration of adductor muscle, fascia or tendon of thigh" }, { "code": "NC76.2Z", "title": "Injury of adductor muscle, fascia or tendon of thigh, unspecified" }, { "code": "NC76.2Y", "title": "Other specified injury of adductor muscle, fascia or tendon of thigh" }, { "code": "NC76.20", "title": "Strain or sprain of adductor muscle, fascia or tendon of thigh" }, { "code": "LD50.Y", "title": "Other specified number anomalies of chromosome X" }, { "code": "NA82.4", "title": "Multiple fractures of ribs" }, { "code": "BA4Z", "title": "Acute ischaemic heart disease, unspecified" }, { "code": "NF0A.6", "title": "Traumatic ischaemia of muscle, not elsewhere classified" }, { "code": "FB32.2Y", "title": "Other specified ischaemic infarction of muscle" }, { "code": "ME00", "title": "Abdominal compartment syndrome" } ]	=== ICD-11 CODES FOUND === [NC76.21] Laceration of adductor muscle, fascia or tendon of thigh Also known as: Laceration of adductor muscle, fascia or tendon of thigh [NC76.2Z] Injury of adductor muscle, fascia or tendon of thigh, unspecified Also known as: Injury of adductor muscle, fascia or tendon of thigh, unspecified \| Injury of adductor muscle, fascia or tendon of thigh [NC76.2Y] Other specified injury of adductor muscle, fascia or tendon of thigh Also known as: Other specified injury of adductor muscle, fascia or tendon of thigh [NC76.20] Strain or sprain of adductor muscle, fascia or tendon of thigh Also known as: Strain or sprain of adductor muscle, fascia or tendon of thigh [LD50.Y] Other specified number anomalies of chromosome X Also known as: Other specified number anomalies of chromosome X \| Female with more than three X chromosomes \| abnormal female chromosomes, with more than three x chromosomes \| Tetrasomy X \| 48 xxxx syndrome [NA82.4] Multiple fractures of ribs Also known as: Multiple fractures of ribs \| rib fractures \| Multiple rib fractures, involving first rib \| Multiple rib fractures, involving two ribs \| Multiple rib fractures, involving three ribs [BA4Z] Acute ischaemic heart disease, unspecified Also known as: Acute ischaemic heart disease, unspecified \| acute coronary syndrome \| ACS - [acute coronary syndrome] \| Silent myocardial ischaemia \| asymptomatic ischemia [NF0A.6] Traumatic ischaemia of muscle, not elsewhere classified Also known as: Traumatic ischaemia of muscle, not elsewhere classified \| Traumatic compartment syndrome \| extremity compartment syndrome NOS \| Arm compartment syndrome \| traumatic arm compartment syndrome Includes: Traumatic compartment syndrome Excludes: anterior tibial syndrome [FB32.2Y] Other specified ischaemic infarction of muscle Also known as: Other specified ischaemic infarction of muscle \| Ischaemic infarction of muscle, multiple sites \| Ischaemic infarction of muscle, shoulder region \| Ischaemic infarction of muscle, acromioclavicular joint \| Ischaemic infarction of muscle, glenohumeral joint [ME00] Abdominal compartment syndrome Definition: Abdominal compartment syndrome is a condition of organ dysfunction caused by increased intra-abdominal pressure (intra-abdominal hypertension), possibly due to intra-abdominal haemorrhage, retroperitoneal haematoma, or intestinal oedema, often occurred after surgical intervention or trauma, or often associated with septic condition. The importance of this clinical entity was recognised recently in the end of the 20th Century. Usually the abdominal distension due to primary ischaemic bowel injury Also known as: Abdominal compartment syndrome === GRAPH WALKS === --- Walk 1 --- [NC76.21] Laceration of adductor muscle, fascia or tendon of thigh --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh --CHILD--> [NC76.21] Laceration of adductor muscle, fascia or tendon of thigh --- Walk 2 --- [NC76.21] Laceration of adductor muscle, fascia or tendon of thigh --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh --CHILD--> [NC76.2Y] Other specified injury of adductor muscle, fascia or tendon of thigh --- Walk 3 --- [NC76.2Z] Injury of adductor muscle, fascia or tendon of thigh, unspecified --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh --CHILD--> [NC76.2Y] Other specified injury of adductor muscle, fascia or tendon of thigh --- Walk 4 --- [NC76.2Z] Injury of adductor muscle, fascia or tendon of thigh, unspecified --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh --CHILD--> [NC76.20] Strain or sprain of adductor muscle, fascia or tendon of thigh --- Walk 5 --- [NC76.2Y] Other specified injury of adductor muscle, fascia or tendon of thigh --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh --CHILD--> [NC76.21] Laceration of adductor muscle, fascia or tendon of thigh --- Walk 6 --- [NC76.2Y] Other specified injury of adductor muscle, fascia or tendon of thigh --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh --CHILD--> [NC76.21] Laceration of adductor muscle, fascia or tendon of thigh	[ "[NC76.21] Laceration of adductor muscle, fascia or tendon of thigh\n --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh\n --CHILD--> [NC76.21] Laceration of adductor muscle, fascia or tendon of thigh", "[NC76.21] Laceration of adductor muscle, fascia or tendon of thigh\n --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh\n --CHILD--> [NC76.2Y] Other specified injury of adductor muscle, fascia or tendon of thigh", "[NC76.2Z] Injury of adductor muscle, fascia or tendon of thigh, unspecified\n --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh\n --CHILD--> [NC76.2Y] Other specified injury of adductor muscle, fascia or tendon of thigh", "[NC76.2Z] Injury of adductor muscle, fascia or tendon of thigh, unspecified\n --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh\n --CHILD--> [NC76.20] Strain or sprain of adductor muscle, fascia or tendon of thigh", "[NC76.2Y] Other specified injury of adductor muscle, fascia or tendon of thigh\n --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh\n --CHILD--> [NC76.21] Laceration of adductor muscle, fascia or tendon of thigh", "[NC76.2Y] Other specified injury of adductor muscle, fascia or tendon of thigh\n --PARENT--> [NC76.2] Injury of adductor muscle, fascia or tendon of thigh\n --CHILD--> [NC76.21] Laceration of adductor muscle, fascia or tendon of thigh" ]	NC76.21	Laceration of adductor muscle, fascia or tendon of thigh	[ { "from_icd11": "NC76.2Z", "icd10_code": "S76212A", "icd10_title": "Strain of adductor muscle, fascia and tendon of left thigh, initial encounter" }, { "from_icd11": "NC76.2Z", "icd10_code": "S76211A", "icd10_title": "Strain of adductor muscle, fascia and tendon of right thigh, initial encounter" }, { "from_icd11": "NC76.2Z", "icd10_code": "S762", "icd10_title": "Injury of adductor muscle, fascia and tendon of thigh" }, { "from_icd11": "NA82.4", "icd10_code": "S2249XA", "icd10_title": "Multiple fractures of ribs, unspecified side, initial encounter for closed fracture" }, { "from_icd11": "NA82.4", "icd10_code": "S2243XD", "icd10_title": "Multiple fractures of ribs, bilateral, subsequent encounter for fracture with routine healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2241XS", "icd10_title": "Multiple fractures of ribs, right side, sequela" }, { "from_icd11": "NA82.4", "icd10_code": "S2249XD", "icd10_title": "Multiple fractures of ribs, unspecified side, subsequent encounter for fracture with routine healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2243XS", "icd10_title": "Multiple fractures of ribs, bilateral, sequela" }, { "from_icd11": "NA82.4", "icd10_code": "S2249XS", "icd10_title": "Multiple fractures of ribs, unspecified side, sequela" }, { "from_icd11": "NA82.4", "icd10_code": "S2249XG", "icd10_title": "Multiple fractures of ribs, unspecified side, subsequent encounter for fracture with delayed healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2243XG", "icd10_title": "Multiple fractures of ribs, bilateral, subsequent encounter for fracture with delayed healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2241XG", "icd10_title": "Multiple fractures of ribs, right side, subsequent encounter for fracture with delayed healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2242XG", "icd10_title": "Multiple fractures of ribs, left side, subsequent encounter for fracture with delayed healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2249XB", "icd10_title": "Multiple fractures of ribs, unspecified side, initial encounter for open fracture" }, { "from_icd11": "NA82.4", "icd10_code": "S2242XA", "icd10_title": "Multiple fractures of ribs, left side, initial encounter for closed fracture" } ]	S76212A	Strain of adductor muscle, fascia and tendon of left thigh, initial encounter
Contrast-enhanced computed tomography (CT) scan showed an ill-defined, hypodense mass of approximately 10.7 × 7.7 cm in the right liver lobe extending to the diaphragm , with moderate enhancement in the periphery during the arterial phase . Magnetic resonance imaging (MRI) of the liver demonstrated this lesion had an increased signal on both T1- and T2- weighted images . No change was observed on T2-spectral presaturation attenuated inversion recovery (SPAIR) sequence , indicating hemorrhaging within the mass. The capsule of the right lobe of liver was unevenly thickened and enhanced, but no obvious enhancement was visible inside the tumor . No lymph node involvement was observed. Fig. 1 Imaging findings of the patient. Computed tomography (CT) scan showed an ill-defined, hypodense mass in the right liver lobe extending to the diaphragm ( A ) with moderate enhancement in the periphery of the mass at 54 s ( B ), 84 s ( C ) and 200 s ( D ) after intravenous injection of contrast. Magnetic resonance imaging (MRI) demonstrated an elliptic mass in the right liver lobe with an increased signal on both T1- ( E ) and T2- ( F ) images; On T2- SPAIR sequence the mass showed high signal indicating haemorrhage within the mass ( G ); H Post-contrast axial T1-weighted sequence showed the capsule of the right lobe of liver was unevenly thickened and enhanced but no obvious enhancement was visible inside the tumor	3.837891	0.783203	sec[1]/p[1]	en	0.999998	34154577	https://doi.org/10.1186/s12905-021-01366-6	[ "liver", "lobe", "enhancement", "contrast", "enhanced", "imaging", "signal", "sequence", "computed", "tomography" ]	[ { "code": "DB9Z", "title": "Diseases of liver, unspecified" }, { "code": "DB97.Z", "title": "Inflammatory liver disease, unspecified" }, { "code": "DB99.7", "title": "Hepatic failure without mention whether acute or chronic" }, { "code": "LB20.0Y", "title": "Other specified structural developmental anomalies of liver" }, { "code": "LB20.0Z", "title": "Structural developmental anomalies of liver, unspecified" }, { "code": "CB40.2", "title": "Pulmonary collapse" }, { "code": "LA75.0", "title": "Accessory lobe of lung" }, { "code": "MD41", "title": "Clinical findings on diagnostic imaging of lung" }, { "code": "LA75.1", "title": "Agenesis of lung" }, { "code": "JA8A.1", "title": "Malformation of placenta" } ]	=== ICD-11 CODES FOUND === [DB9Z] Diseases of liver, unspecified Also known as: Diseases of liver, unspecified \| liver disease \| liver condition NOS \| organ liver disease \| hepatopathy [DB97.Z] Inflammatory liver disease, unspecified Also known as: Inflammatory liver disease, unspecified \| Certain specified inflammatory liver diseases \| Nonspecific reactive hepatitis \| inflammatory liver disease \| hepatitis NOS [DB99.7] Hepatic failure without mention whether acute or chronic Also known as: Hepatic failure without mention whether acute or chronic \| liver decompensation \| liver function failure \| hepatic failure NOS \| liver failure NOS [LB20.0Y] Other specified structural developmental anomalies of liver Also known as: Other specified structural developmental anomalies of liver \| Alagille syndrome \| Alagille-Watson syndrome \| Arteriohepatic dysplasia \| Syndromic bile duct paucity [LB20.0Z] Structural developmental anomalies of liver, unspecified Also known as: Structural developmental anomalies of liver, unspecified \| Structural developmental anomalies of liver \| Malformations of liver \| congenital anomaly of liver \| congenital malformation of liver [CB40.2] Pulmonary collapse Also known as: Pulmonary collapse \| Atelectasis \| lung collapse \| pulmonary atelectasis \| pulmonary collapse with atelectasis Includes: Atelectasis Excludes: Primary atelectasis of newborn \| tuberculous atelectasis, not confirmed \| tuberculous atelectasis, confirmed [LA75.0] Accessory lobe of lung Definition: An extra lobe of lung beyond the 3 on the right and the 2 on the left Also known as: Accessory lobe of lung \| supernumerary lung lobe \| azygos lobe of lung \| azygos lobe fissure of lung \| azygos lobe [MD41] Clinical findings on diagnostic imaging of lung Definition: Clinical findings on diagnostic imaging of lung is findings on diagnostic imaging of the lung which don't appear in normal status of the body. Diagnostic imaging refers to technologies that doctors use to look inside body for clues about a medical condition. X-rays, CT scans, nuclear medicine scans, MRI scans and ultrasound are all types of diagnostic imaging. Also known as: Clinical findings on diagnostic imaging of lung \| abnormal diagnostic imaging of lung \| Hyperinflation of lung \| Lung mass \| Pulmonary lobe mass [LA75.1] Agenesis of lung Definition: This refers to the absence or rudimentary residua of an undeveloped lung. Also known as: Agenesis of lung \| Pulmonary agenesis \| absence of lung \| aplasia of lung \| apulmonism [JA8A.1] Malformation of placenta Also known as: Malformation of placenta \| variation of placenta form \| deformity of placenta \| placental deformity \| Abnormal placenta NOS === GRAPH WALKS === --- Walk 1 --- [DB9Z] Diseases of liver, unspecified --PARENT--> [?] Diseases of liver --EXCLUDES--> [?] Unspecified jaundice Def: A clinical manifestation of hyperbilirubinemia of unspecified origin, characterised by the yellowish staining of the skin; mucus membranes and sclera.... --- Walk 2 --- [DB9Z] Diseases of liver, unspecified --PARENT--> [?] Diseases of liver --CHILD--> [DB91] Acute or subacute hepatic failure Def: Acute and subacute liver failure is characterised by onset of coagulopathy and/or hepatic encephalopathy within 8 weeks of onset of symptoms in a patient without previously known liver diseases.... --- Walk 3 --- [DB97.Z] Inflammatory liver disease, unspecified --PARENT--> [DB97] Certain specified inflammatory liver diseases --RELATED_TO--> [?] Hepatic sarcoidosis Def: This is a syndrome involving abnormal collections of chronic inflammatory cells (granulomas) that can form as nodules in multiple organs, of the liver.... --- Walk 4 --- [DB97.Z] Inflammatory liver disease, unspecified --PARENT--> [DB97] Certain specified inflammatory liver diseases --EXCLUDES--> [?] Drug-induced or toxic liver disease Def: Drug-induced or toxic liver disease is hepatotoxicity as injury to the liver that is associated with impaired liver function caused by exposure to a drug or another noninfectious agent.... --- Walk 5 --- [DB99.7] Hepatic failure without mention whether acute or chronic --PARENT--> [DB99] Certain specified diseases of liver Def: This is a group of conditions characterised as being in or associated with the liver that are not classified elsewhere.... --EXCLUDES--> [?] Fibropolycystic liver disease --- Walk 6 --- [DB99.7] Hepatic failure without mention whether acute or chronic --PARENT--> [DB99] Certain specified diseases of liver Def: This is a group of conditions characterised as being in or associated with the liver that are not classified elsewhere.... --EXCLUDES--> [?] Drug-induced or toxic liver disease Def: Drug-induced or toxic liver disease is hepatotoxicity as injury to the liver that is associated with impaired liver function caused by exposure to a drug or another noninfectious agent....	[ "[DB9Z] Diseases of liver, unspecified\n --PARENT--> [?] Diseases of liver\n --EXCLUDES--> [?] Unspecified jaundice\n Def: A clinical manifestation of hyperbilirubinemia of unspecified origin, characterised by the yellowish staining of the skin; mucus membranes and sclera....", "[DB9Z] Diseases of liver, unspecified\n --PARENT--> [?] Diseases of liver\n --CHILD--> [DB91] Acute or subacute hepatic failure\n Def: Acute and subacute liver failure is characterised by onset of coagulopathy and/or hepatic encephalopathy within 8 weeks of onset of symptoms in a patient without previously known liver diseases....", "[DB97.Z] Inflammatory liver disease, unspecified\n --PARENT--> [DB97] Certain specified inflammatory liver diseases\n --RELATED_TO--> [?] Hepatic sarcoidosis\n Def: This is a syndrome involving abnormal collections of chronic inflammatory cells (granulomas) that can form as nodules in multiple organs, of the liver....", "[DB97.Z] Inflammatory liver disease, unspecified\n --PARENT--> [DB97] Certain specified inflammatory liver diseases\n --EXCLUDES--> [?] Drug-induced or toxic liver disease\n Def: Drug-induced or toxic liver disease is hepatotoxicity as injury to the liver that is associated with impaired liver function caused by exposure to a drug or another noninfectious agent....", "[DB99.7] Hepatic failure without mention whether acute or chronic\n --PARENT--> [DB99] Certain specified diseases of liver\n Def: This is a group of conditions characterised as being in or associated with the liver that are not classified elsewhere....\n --EXCLUDES--> [?] Fibropolycystic liver disease", "[DB99.7] Hepatic failure without mention whether acute or chronic\n --PARENT--> [DB99] Certain specified diseases of liver\n Def: This is a group of conditions characterised as being in or associated with the liver that are not classified elsewhere....\n --EXCLUDES--> [?] Drug-induced or toxic liver disease\n Def: Drug-induced or toxic liver disease is hepatotoxicity as injury to the liver that is associated with impaired liver function caused by exposure to a drug or another noninfectious agent...." ]	DB9Z	Diseases of liver, unspecified	[ { "from_icd11": "DB9Z", "icd10_code": "K7681", "icd10_title": "Hepatopulmonary syndrome" }, { "from_icd11": "DB9Z", "icd10_code": "K7689", "icd10_title": "Other specified diseases of liver" }, { "from_icd11": "DB9Z", "icd10_code": "K769", "icd10_title": "Liver disease, unspecified" }, { "from_icd11": "DB9Z", "icd10_code": "K77", "icd10_title": "Liver disorders in diseases classified elsewhere" }, { "from_icd11": "DB9Z", "icd10_code": "K762", "icd10_title": "Central hemorrhagic necrosis of liver" }, { "from_icd11": "DB9Z", "icd10_code": "K70-K77", "icd10_title": "" }, { "from_icd11": "DB9Z", "icd10_code": "K778", "icd10_title": "" }, { "from_icd11": "DB9Z", "icd10_code": "K72", "icd10_title": "Hepatic failure, not elsewhere classified" }, { "from_icd11": "DB9Z", "icd10_code": "K76", "icd10_title": "Other diseases of liver" }, { "from_icd11": "DB9Z", "icd10_code": "K768", "icd10_title": "Other specified diseases of liver" }, { "from_icd11": "DB97.Z", "icd10_code": "K7581", "icd10_title": "Nonalcoholic steatohepatitis (NASH)" }, { "from_icd11": "DB97.Z", "icd10_code": "K7589", "icd10_title": "Other specified inflammatory liver diseases" }, { "from_icd11": "DB97.Z", "icd10_code": "K759", "icd10_title": "Inflammatory liver disease, unspecified" }, { "from_icd11": "DB97.Z", "icd10_code": "K752", "icd10_title": "Nonspecific reactive hepatitis" }, { "from_icd11": "DB97.Z", "icd10_code": "K75", "icd10_title": "Other inflammatory liver diseases" } ]	K7681	Hepatopulmonary syndrome
In December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged from Wuhan/China and triggered the worldwide coronavirus disease 2019 (COVID-19) pandemic . Clinically relevant SARS-CoV-2 infections primarily cause pneumonia, which can potentially result in acute respiratory distress syndrome (ARDS), but other organ systems than the patient’s lungs can subsequently be affected, too . World Health Organization (WHO) guidelines recommend rapid antigen diagnostic tests (Ag-RDT) as a fast, widely available early detection method for SARS-CoV-2 proteins. These tests should always be complemented by a nucleic acid amplification test (NAAT) . Antigen-specific point-of-care tests contribute to the overall testing capacities due to their simple handling and rapid and laboratory-independent results. Ag-RDT are especially useful in pre-symptomatic or early symptomatic patients and in communities with a high prevalence of active SARS-CoV-2 infections. Especially in regional hospitals Ag-RDTs are used to detect SARS-CoV-2 infections, since results of the gold standard NAAT are usually available only on the following day . Here, we present the case of an assumed COVID-19 pneumonia diagnosed with an initial positive Ag-RDT result that post-mortem turned out to be C. canimorsus sepsis, which resulted in a lethal outcome . Fig. 1 Timeline from dog leash injury to death of the patient	4.132813	0.913574	sec[0]/p[0]	en	0.999997	34344315	https://doi.org/10.1186/s12879-021-06422-y	[ "sars", "infections", "respiratory", "coronavirus", "covid", "pneumonia", "which", "rapid", "antigen", "available" ]	[ { "code": "1D65", "title": "Severe acute respiratory syndrome" }, { "code": "RA01.0", "title": "COVID-19, virus identified" }, { "code": "RA01.0/CA40.1Z", "title": "COVID-19 with pneumonia, SARS-CoV-2 identified" }, { "code": "RA01.1/CA40.1Z", "title": "COVID-19 with pneumonia, SARS-CoV-2 not identified" }, { "code": "1H0Z", "title": "Infection, unspecified" }, { "code": "1G40", "title": "Sepsis without septic shock" }, { "code": "FA10.Z", "title": "Direct infections of joint, unspecified" }, { "code": "1D9Z", "title": "Unspecified viral infection of unspecified site" }, { "code": "1A40.Z", "title": "Infectious gastroenteritis or colitis without specification of infectious agent" }, { "code": "CB7Z", "title": "Diseases of the respiratory system, unspecified" } ]	=== ICD-11 CODES FOUND === [1D65] Severe acute respiratory syndrome Definition: A disease of the respiratory system, caused by an infection with coronavirus. This disease is characterised by fever, headache, cough, myalgia, tachycardia, or diarrhoea. This disease may also lead to pneumonia. Transmission is by direct contact, inhalation of infected respiratory secretions, or airborne transmission. Confirmation is by identification of coronavirus in a blood, stool, respiratory secretions, or body tissue sample. Also known as: Severe acute respiratory syndrome \| SARS - [severe acute respiratory syndrome] Excludes: COVID-19, virus identified \| COVID-19, virus not identified [RA01.0] COVID-19, virus identified Also known as: COVID-19, virus identified \| 2019-new Coronavirus acute respiratory disease (deprecated) \| 2019-nCoV acute respiratory disease [temporary name] (deprecated) \| Coronavirus disease 2019 \| SARS-CoV-2 disease Includes: Coronavirus disease 2019 \| COVID-19 NOS Excludes: Coronavirus infection, unspecified site \| Middle East respiratory syndrome \| Severe acute respiratory syndrome [1H0Z] Infection, unspecified Also known as: Infection, unspecified \| infection NOS \| infectious disease NOS \| infection unknown \| infection process NOS [1G40] Sepsis without septic shock Definition: Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Also known as: Sepsis without septic shock \| sepsis without septic shock with known organism \| Sepsis-associated hypotension \| Unspecified sepsis \| general septic intoxication Excludes: Septicaemia \| Sepsis of fetus or newborn [FA10.Z] Direct infections of joint, unspecified Also known as: Direct infections of joint, unspecified \| Direct infections of joint \| septic arthritis \| pyogenic arthritis \| arthritis due to infection [1D9Z] Unspecified viral infection of unspecified site Also known as: Unspecified viral infection of unspecified site \| viral infection NOS \| viral disorder NOS \| disease caused by virus \| unspecified viremia [1A40.Z] Infectious gastroenteritis or colitis without specification of infectious agent Also known as: Infectious gastroenteritis or colitis without specification of infectious agent \| Gastroenteritis or colitis without specification of infectious agent \| diarrhoea and gastroenteritis of presumed infectious origin \| diarrhoeal enteritis \| GE - [gastroenteritis] [CB7Z] Diseases of the respiratory system, unspecified Also known as: Diseases of the respiratory system, unspecified \| disorder of respiratory system \| respiratory disease NOS \| respiratory tract disease \| respiratory disorder NOS === GRAPH WALKS === --- Walk 1 --- [1D65] Severe acute respiratory syndrome Def: A disease of the respiratory system, caused by an infection with coronavirus. This disease is characterised by fever, headache, cough, myalgia, tachycardia, or diarrhoea. This disease may also lead to... --EXCLUDES--> [?] COVID-19, virus identified --CHILD--> [?] COVID-19 with pneumonia, SARS-CoV-2 identified --- Walk 2 --- [1D65] Severe acute respiratory syndrome Def: A disease of the respiratory system, caused by an infection with coronavirus. This disease is characterised by fever, headache, cough, myalgia, tachycardia, or diarrhoea. This disease may also lead to... --PARENT--> [?] Certain zoonotic viral diseases --CHILD--> [1D61] Arenavirus disease --- Walk 3 --- [RA01.0] COVID-19, virus identified --EXCLUDES--> [?] Coronavirus infection, unspecified site --PARENT--> [?] Viral infection of unspecified site --- Walk 4 --- [RA01.0] COVID-19, virus identified --EXCLUDES--> [?] Coronavirus infection, unspecified site --EXCLUDES--> [?] COVID-19, virus identified --- Walk 5 --- [1H0Z] Infection, unspecified --PARENT--> [01] Certain infectious or parasitic diseases Def: This chapter includes certain conditions caused by pathogenic organisms or microorganisms, such as bacteria, viruses, parasites or fungi.... --EXCLUDES--> [?] Infection arising from device, implant or graft, not elsewhere classified --- Walk 6 --- [1H0Z] Infection, unspecified --PARENT--> [01] Certain infectious or parasitic diseases Def: This chapter includes certain conditions caused by pathogenic organisms or microorganisms, such as bacteria, viruses, parasites or fungi.... --RELATED_TO--> [?] Human prion diseases Def: Human prion diseases or transmissible spongiform encephalopathies are rare transmissible diseases affecting the central nervous system. The infectious agents are composed of an abnormal isoform of a h...	[ "[1D65] Severe acute respiratory syndrome\n Def: A disease of the respiratory system, caused by an infection with coronavirus. This disease is characterised by fever, headache, cough, myalgia, tachycardia, or diarrhoea. This disease may also lead to...\n --EXCLUDES--> [?] COVID-19, virus identified\n --CHILD--> [?] COVID-19 with pneumonia, SARS-CoV-2 identified", "[1D65] Severe acute respiratory syndrome\n Def: A disease of the respiratory system, caused by an infection with coronavirus. This disease is characterised by fever, headache, cough, myalgia, tachycardia, or diarrhoea. This disease may also lead to...\n --PARENT--> [?] Certain zoonotic viral diseases\n --CHILD--> [1D61] Arenavirus disease", "[RA01.0] COVID-19, virus identified\n --EXCLUDES--> [?] Coronavirus infection, unspecified site\n --PARENT--> [?] Viral infection of unspecified site", "[RA01.0] COVID-19, virus identified\n --EXCLUDES--> [?] Coronavirus infection, unspecified site\n --EXCLUDES--> [?] COVID-19, virus identified", "[1H0Z] Infection, unspecified\n --PARENT--> [01] Certain infectious or parasitic diseases\n Def: This chapter includes certain conditions caused by pathogenic organisms or microorganisms, such as bacteria, viruses, parasites or fungi....\n --EXCLUDES--> [?] Infection arising from device, implant or graft, not elsewhere classified", "[1H0Z] Infection, unspecified\n --PARENT--> [01] Certain infectious or parasitic diseases\n Def: This chapter includes certain conditions caused by pathogenic organisms or microorganisms, such as bacteria, viruses, parasites or fungi....\n --RELATED_TO--> [?] Human prion diseases\n Def: Human prion diseases or transmissible spongiform encephalopathies are rare transmissible diseases affecting the central nervous system. The infectious agents are composed of an abnormal isoform of a h..." ]	1D65	Severe acute respiratory syndrome	[ { "from_icd11": "1D65", "icd10_code": "U04", "icd10_title": "" }, { "from_icd11": "1D65", "icd10_code": "U049", "icd10_title": "" }, { "from_icd11": "1H0Z", "icd10_code": "B999", "icd10_title": "Unspecified infectious disease" }, { "from_icd11": "1H0Z", "icd10_code": "A312", "icd10_title": "Disseminated mycobacterium avium-intracellulare complex (DMAC)" }, { "from_icd11": "1H0Z", "icd10_code": "B998", "icd10_title": "Other infectious disease" }, { "from_icd11": "1H0Z", "icd10_code": "A249", "icd10_title": "Melioidosis, unspecified" }, { "from_icd11": "1H0Z", "icd10_code": "R6511", "icd10_title": "Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction" }, { "from_icd11": "1H0Z", "icd10_code": "R6510", "icd10_title": "Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction" }, { "from_icd11": "1H0Z", "icd10_code": "A318", "icd10_title": "Other mycobacterial infections" }, { "from_icd11": "1H0Z", "icd10_code": "A319", "icd10_title": "Mycobacterial infection, unspecified" }, { "from_icd11": "1H0Z", "icd10_code": "B948", "icd10_title": "Sequelae of other specified infectious and parasitic diseases" }, { "from_icd11": "1H0Z", "icd10_code": "B949", "icd10_title": "Sequelae of unspecified infectious and parasitic disease" }, { "from_icd11": "1H0Z", "icd10_code": "K77", "icd10_title": "Liver disorders in diseases classified elsewhere" }, { "from_icd11": "1H0Z", "icd10_code": "N771", "icd10_title": "Vaginitis, vulvitis and vulvovaginitis in diseases classified elsewhere" }, { "from_icd11": "1H0Z", "icd10_code": "I", "icd10_title": "" } ]	U04
Eight units of packed red blood cells (RBC) were transfused to improve the severe anemia from day 1 to day 3 of admission (day 1: four units, day 2: two units, day 3: two units). Enalapril (1.25 mg/day) was started, and furosemide (10 mg/day) was intravenously administered. The hemoglobin level improved from 4.6 g/dL at presentation (day 1) to 11.8 g/dL on day 4. Pulmonary congestion and pleural effusion worsened after the RBC transfusion. The patient’s weight increased from 34.0 kg (day 1) to 35.4 kg (day 11). She required 3 L of oxygen per minute to maintain a SpO 2 > 90%. She continued to have tachypnoea (respiratory rate: 25 per minute), sinus tachycardia (heart rate: 101 bpm), high blood pressure (178/89 mmHg), and intermittent chest pain (day 10). Adequate urine output was maintained with intravenous furosemide administration. Non-invasive positive pressure ventilation (NIPPV) was administrated between day 6 to day 9; low-pressure settings were used to prevent excessive reduction of venous return. However, these treatments failed to sufficiently improve pulmonary congestion. The chest radiograph showed a bilateral butterfly shadow . TTE at day 11 revealed a decreased LVEF (40%). IVC collapsed less than 50% on inspiration (expiratory IVC diameter 16.2 mm, inspiratory 10.8 mm). The AVA by planimetry was 0.37 cm 2 , peak pressure gradient was 47 mmHg, and peak aortic jet velocity was 3.4 m/sec .	3.966797	0.975098	sec[1]/p[7]	en	0.999999	PMC9805905	https://doi.org/10.7759/cureus.32142	[ "pressure", "blood", "improve", "furosemide", "pulmonary", "congestion", "minute", "mmhg", "chest", "peak" ]	[ { "code": "EH90.Z", "title": "Pressure ulcer of unspecified grade" }, { "code": "MB23.L", "title": "Pressured speech" }, { "code": "MD30.Z", "title": "Chest pain, unspecified" }, { "code": "CB22.Y", "title": "Other specified diseases of mediastinum, not elsewhere classified" }, { "code": "BA2Z", "title": "Hypotension, unspecified" }, { "code": "3C0Z", "title": "Diseases of the blood or blood-forming organs, unspecified" }, { "code": "MF50.4Z", "title": "Haematuria, unspecified" }, { "code": "MA12.1", "title": "Finding of cocaine in blood" }, { "code": "MA12.4", "title": "Finding of steroid agent in blood" }, { "code": "MA12.2", "title": "Finding of hallucinogen in blood" } ]	=== ICD-11 CODES FOUND === [EH90.Z] Pressure ulcer of unspecified grade Also known as: Pressure ulcer of unspecified grade \| Pressure ulceration \| pressure injury \| pressure ulcer \| decubitus ulcer [MB23.L] Pressured speech Definition: Speech in which the person feels undue pressure to get the words out. The person’s speech is usually rapid, loud, and emphatic and may be difficult or impossible to interrupt. Frequently, the person talks without any social stimulation and may continue to talk even though no one is listening. Also known as: Pressured speech Excludes: Schizophrenia or other primary psychotic disorders \| Bipolar or related disorders [MD30.Z] Chest pain, unspecified Also known as: Chest pain, unspecified \| Pain in throat or chest \| chest pain NOS \| pain in chest \| chest pressure [CB22.Y] Other specified diseases of mediastinum, not elsewhere classified Also known as: Other specified diseases of mediastinum, not elsewhere classified \| Hernia of mediastinum \| mediastinal hernia \| mediastinal herniation \| Infectious mediastinitis [BA2Z] Hypotension, unspecified Also known as: Hypotension, unspecified \| hypopiesis \| low blood pressure \| arterial hypotension NOS \| decreased blood pressure [3C0Z] Diseases of the blood or blood-forming organs, unspecified Also known as: Diseases of the blood or blood-forming organs, unspecified \| Blood, lymph or spleen disease \| blood condition NOS \| blood disorder NOS \| bone marrow disease NOS [MF50.4Z] Haematuria, unspecified Also known as: Haematuria, unspecified \| Haematuria \| blood in urine \| urinary blood \| haematuria NOS [MA12.1] Finding of cocaine in blood Also known as: Finding of cocaine in blood \| cocaine in blood [MA12.4] Finding of steroid agent in blood Also known as: Finding of steroid agent in blood \| steroid in blood [MA12.2] Finding of hallucinogen in blood Also known as: Finding of hallucinogen in blood \| hallucinogen in blood === GRAPH WALKS === --- Walk 1 --- [EH90.Z] Pressure ulcer of unspecified grade --PARENT--> [EH90] Pressure ulceration Def: Pressure ulcers result from localised injury and ischaemic necrosis of skin and underlying tissues due to prolonged pressure, or pressure in combination with shear; bony prominences of the body are th... --EXCLUDES--> [?] Erosion or ectropion of cervix uteri Def: A condition of the cervix uteri, caused by an increase in the total estrogen level in the body. This condition is characterised by protrusion and transformation of the endocervical columnar epithelium... --- Walk 2 --- [EH90.Z] Pressure ulcer of unspecified grade --PARENT--> [EH90] Pressure ulceration Def: Pressure ulcers result from localised injury and ischaemic necrosis of skin and underlying tissues due to prolonged pressure, or pressure in combination with shear; bony prominences of the body are th... --PARENT--> [?] Skin disorders provoked by external factors Def: A large group of skin disorders due to exposure of the skin to various external physical, chemical or environmental insults including chemical irritants and allergens, poisons, pressure, cold, heat, s... --- Walk 3 --- [MB23.L] Pressured speech Def: Speech in which the person feels undue pressure to get the words out. The person’s speech is usually rapid, loud, and emphatic and may be difficult or impossible to interrupt. Frequently, the person t... --EXCLUDES--> [?] Bipolar or related disorders Def: Bipolar and related disorders are episodic mood disorders defined by the occurrence of Manic, Mixed or Hypomanic episodes or symptoms. These episodes typically alternate over the course of these disor... --CHILD--> [?] Bipolar type II disorder Def: Bipolar type II disorder is an episodic mood disorder defined by the occurrence of one or more hypomanic episodes and at least one depressive episode. A hypomanic episode is a persistent mood state la... --- Walk 4 --- [MB23.L] Pressured speech Def: Speech in which the person feels undue pressure to get the words out. The person’s speech is usually rapid, loud, and emphatic and may be difficult or impossible to interrupt. Frequently, the person t... --EXCLUDES--> [?] Schizophrenia or other primary psychotic disorders Def: Schizophrenia and other primary psychotic disorders are characterised by significant impairments in reality testing and alterations in behaviour manifest in positive symptoms such as persistent delusi... --CHILD--> [?] Schizoaffective disorder Def: Schizoaffective disorder is an episodic disorder in which the diagnostic requirements of schizophrenia and a manic, mixed, or moderate or severe depressive episode are met within the same episode of i... --- Walk 5 --- [MD30.Z] Chest pain, unspecified --PARENT--> [MD30] Pain in throat or chest Def: Pain in throat and chest means having pain sensation in throat or chest. Throat is a tube that carries food to oesophagus and air to windpipe and larynx. The technical name for throat is pharynx.... --EXCLUDES--> [?] Cervical spine pain Def: This is a condition which is usually characterised by pain or discomfort in the neck region and can be caused by numerous spinal problems. It may be a feature of virtually every disorder and disease t... --- Walk 6 --- [MD30.Z] Chest pain, unspecified --PARENT--> [MD30] Pain in throat or chest Def: Pain in throat and chest means having pain sensation in throat or chest. Throat is a tube that carries food to oesophagus and air to windpipe and larynx. The technical name for throat is pharynx.... --RELATED_TO--> [?] Pain in throat Def: Pain in throat means having pain sensation in throat. Throat is a tube that carries food to oesophagus and air to windpipe and larynx....	[ "[EH90.Z] Pressure ulcer of unspecified grade\n --PARENT--> [EH90] Pressure ulceration\n Def: Pressure ulcers result from localised injury and ischaemic necrosis of skin and underlying tissues due to prolonged pressure, or pressure in combination with shear; bony prominences of the body are th...\n --EXCLUDES--> [?] Erosion or ectropion of cervix uteri\n Def: A condition of the cervix uteri, caused by an increase in the total estrogen level in the body. This condition is characterised by protrusion and transformation of the endocervical columnar epithelium...", "[EH90.Z] Pressure ulcer of unspecified grade\n --PARENT--> [EH90] Pressure ulceration\n Def: Pressure ulcers result from localised injury and ischaemic necrosis of skin and underlying tissues due to prolonged pressure, or pressure in combination with shear; bony prominences of the body are th...\n --PARENT--> [?] Skin disorders provoked by external factors\n Def: A large group of skin disorders due to exposure of the skin to various external physical, chemical or environmental insults including chemical irritants and allergens, poisons, pressure, cold, heat, s...", "[MB23.L] Pressured speech\n Def: Speech in which the person feels undue pressure to get the words out. The person’s speech is usually rapid, loud, and emphatic and may be difficult or impossible to interrupt. Frequently, the person t...\n --EXCLUDES--> [?] Bipolar or related disorders\n Def: Bipolar and related disorders are episodic mood disorders defined by the occurrence of Manic, Mixed or Hypomanic episodes or symptoms. These episodes typically alternate over the course of these disor...\n --CHILD--> [?] Bipolar type II disorder\n Def: Bipolar type II disorder is an episodic mood disorder defined by the occurrence of one or more hypomanic episodes and at least one depressive episode. A hypomanic episode is a persistent mood state la...", "[MB23.L] Pressured speech\n Def: Speech in which the person feels undue pressure to get the words out. The person’s speech is usually rapid, loud, and emphatic and may be difficult or impossible to interrupt. Frequently, the person t...\n --EXCLUDES--> [?] Schizophrenia or other primary psychotic disorders\n Def: Schizophrenia and other primary psychotic disorders are characterised by significant impairments in reality testing and alterations in behaviour manifest in positive symptoms such as persistent delusi...\n --CHILD--> [?] Schizoaffective disorder\n Def: Schizoaffective disorder is an episodic disorder in which the diagnostic requirements of schizophrenia and a manic, mixed, or moderate or severe depressive episode are met within the same episode of i...", "[MD30.Z] Chest pain, unspecified\n --PARENT--> [MD30] Pain in throat or chest\n Def: Pain in throat and chest means having pain sensation in throat or chest. Throat is a tube that carries food to oesophagus and air to windpipe and larynx. The technical name for throat is pharynx....\n --EXCLUDES--> [?] Cervical spine pain\n Def: This is a condition which is usually characterised by pain or discomfort in the neck region and can be caused by numerous spinal problems. It may be a feature of virtually every disorder and disease t...", "[MD30.Z] Chest pain, unspecified\n --PARENT--> [MD30] Pain in throat or chest\n Def: Pain in throat and chest means having pain sensation in throat or chest. Throat is a tube that carries food to oesophagus and air to windpipe and larynx. The technical name for throat is pharynx....\n --RELATED_TO--> [?] Pain in throat\n Def: Pain in throat means having pain sensation in throat. Throat is a tube that carries food to oesophagus and air to windpipe and larynx...." ]	EH90.Z	Pressure ulcer of unspecified grade	[ { "from_icd11": "EH90.Z", "icd10_code": "L89623", "icd10_title": "Pressure ulcer of left heel, stage 3" }, { "from_icd11": "EH90.Z", "icd10_code": "L89621", "icd10_title": "Pressure ulcer of left heel, stage 1" }, { "from_icd11": "EH90.Z", "icd10_code": "L89899", "icd10_title": "Pressure ulcer of other site, unspecified stage" }, { "from_icd11": "EH90.Z", "icd10_code": "L89620", "icd10_title": "Pressure ulcer of left heel, unstageable" }, { "from_icd11": "EH90.Z", "icd10_code": "L89622", "icd10_title": "Pressure ulcer of left heel, stage 2" }, { "from_icd11": "EH90.Z", "icd10_code": "L89892", "icd10_title": "Pressure ulcer of other site, stage 2" }, { "from_icd11": "EH90.Z", "icd10_code": "L89519", "icd10_title": "Pressure ulcer of right ankle, unspecified stage" }, { "from_icd11": "EH90.Z", "icd10_code": "L89891", "icd10_title": "Pressure ulcer of other site, stage 1" }, { "from_icd11": "EH90.Z", "icd10_code": "L89610", "icd10_title": "Pressure ulcer of right heel, unstageable" }, { "from_icd11": "EH90.Z", "icd10_code": "L89893", "icd10_title": "Pressure ulcer of other site, stage 3" }, { "from_icd11": "EH90.Z", "icd10_code": "L89890", "icd10_title": "Pressure ulcer of other site, unstageable" }, { "from_icd11": "EH90.Z", "icd10_code": "L89629", "icd10_title": "Pressure ulcer of left heel, unspecified stage" }, { "from_icd11": "EH90.Z", "icd10_code": "L89619", "icd10_title": "Pressure ulcer of right heel, unspecified stage" }, { "from_icd11": "EH90.Z", "icd10_code": "L8945", "icd10_title": "Pressure ulcer of contiguous site of back, buttock and hip, unstageable" }, { "from_icd11": "EH90.Z", "icd10_code": "L89894", "icd10_title": "Pressure ulcer of other site, stage 4" } ]	L89623	Pressure ulcer of left heel, stage 3
We present two representative cases: PMMA-PS and CPS . The patients received good follow-up, including imaging and clinical evaluations. Figure 2 Radiological images of a representative case with PMMA-PS. ( A – L ) A 62-year-old osteoporotic male with isthmic spondylolisthesis in the L4/L5 segments. ( A – D ) Preoperative X-rays and CT showed forward slip of the L4 vertebra and L4 spondylolysis. ( E – H ) Postoperative X-ray and CT showed that the internal fixation position was good and that the bone cement was in the vertebrae. ( I – L ) Postoperative X-ray and CT at 36 months after fusion surgery showed that the internal fixation device did not loosen or break, the vertebra did not show slippage, the intervertebral fusion was good, the bone cement was well filled, and there was no obvious cement leakage. Figure 3 Radiological images of a representative case with CPS. ( A – L ) A 61-year-old osteoporotic female with isthmic spondylolisthesis in the L5/S1 segments. ( A – D ) Preoperative X-rays and CT showed forward slip of the L5 vertebra and L5 spondylolysis. ( E – H ) Postoperative X-rays and CT showed that the internal fixation position was good and that the L5 vertebra was well reset. ( I – L ) Postoperative X-ray and CT at 24 months after fusion surgery showed that the internal fixation device did not loosen or break, the vertebra did not show slippage, and the intervertebral fusion was good.	3.603516	0.929199	sec[2]/p[2]	en	0.999997	36646752	https://doi.org/10.1038/s41598-023-27539-x	[ "that", "good", "vertebra", "postoperative", "fixation", "fusion", "representative", "rays", "cement", "pmma" ]	[ { "code": "8A80.Z", "title": "Migraine, unspecified" }, { "code": "QA76", "title": "Medication or substance that is known to be an allergen without injury or harm" }, { "code": "PL13.6", "title": "Medication or substance that is known to be an allergen, as mode of injury or harm" }, { "code": "9C40.A0", "title": "Papilloedema" }, { "code": "PA6Z", "title": "Unintentional fall from unspecified height" }, { "code": "4B40.2", "title": "Good syndrome" }, { "code": "6B24.0", "title": "Hoarding disorder with fair to good insight" }, { "code": "6B21.0", "title": "Body dysmorphic disorder with fair to good insight" }, { "code": "6B22.0", "title": "Olfactory reference disorder with fair to good insight" }, { "code": "6B23.0", "title": "Hypochondriasis with fair to good insight" } ]	=== ICD-11 CODES FOUND === [8A80.Z] Migraine, unspecified Also known as: Migraine, unspecified \| Migraine [QA76] Medication or substance that is known to be an allergen without injury or harm Definition: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm. Also known as: Medication or substance that is known to be an allergen without injury or harm Excludes: Medication or substance that is known to be an allergen, as mode of injury or harm [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm Also known as: Medication or substance that is known to be an allergen, as mode of injury or harm \| medication error relating to known allergy to drug or substance \| adverse drug event relating to known allergy to drug or substance [9C40.A0] Papilloedema Definition: Optic disc swelling that results from increased intracranial pressure Also known as: Papilloedema \| Optic disc swelling that results from increased intracranial pressure Includes: Optic disc swelling that results from increased intracranial pressure [PA6Z] Unintentional fall from unspecified height Also known as: Unintentional fall from unspecified height \| fall NOS \| accidental fall \| fall causing injury that resulted in death \| fell NOS [4B40.2] Good syndrome Definition: This is a condition that occurs in adults in whom hypogammaglobulinemia, deficient cell-mediated immunity, and benign thymoma may develop almost simultaneously. Also known as: Good syndrome \| Thymoma immunodeficiency [6B24.0] Hoarding disorder with fair to good insight Definition: All definitional requirements of hoarding disorder are met. The individual recognizes that hoarding-related beliefs and behaviours (pertaining to excessive acquisition, difficulty discarding, or clutter) are problematic. This qualifier level may still be applied if, at circumscribed times (e.g., when being forced to discard items), the individual demonstrates no insight. Also known as: Hoarding disorder with fair to good insight [6B21.0] Body dysmorphic disorder with fair to good insight Definition: All definitional requirements of body dysmorphic disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true and is willing to accept an alternative explanation for his or her experience. At circumscribed times (e.g., when highly anxious), the individual may demonstrate no insight. Also known as: Body dysmorphic disorder with fair to good insight [6B22.0] Olfactory reference disorder with fair to good insight Definition: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true and is willing to accept an alternative explanation for his or her experience. At circumscribed times (e.g., when highly anxious), the individual may demonstrate no insight. Also known as: Olfactory reference disorder with fair to good insight [6B23.0] Hypochondriasis with fair to good insight Definition: All definitional requirements of hypochondriasis are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true and is willing to accept an alternative explanation for his or her experience. At circumscribed times (e.g., when highly anxious), the individual may demonstrate no insight. Also known as: Hypochondriasis with fair to good insight === GRAPH WALKS === --- Walk 1 --- [8A80.Z] Migraine, unspecified --PARENT--> [8A80] Migraine Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a... --CHILD--> [8A80.1] Migraine with aura Def: Recurrent attacks, lasting minutes, of unilateral fully-reversible visual, sensory or other central nervous system symptoms that usually develop gradually and are usually followed by headache and asso... --- Walk 2 --- [8A80.Z] Migraine, unspecified --PARENT--> [8A80] Migraine Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a... --CHILD--> [8A80.0] Migraine without aura Def: Recurrent headache disorder manifesting in attacks lasting 4-72 hours. The duration of attacks may be shorter in children. Typical characteristics of the headache are unilateral location, pulsating qu... --- Walk 3 --- [QA76] Medication or substance that is known to be an allergen without injury or harm Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm.... --PARENT--> [?] Circumstances associated with exposure to a drug, medicament or biological substance influencing the episode of care without injury or harm --PARENT--> [?] Health care related circumstances influencing the episode of care without injury or harm --- Walk 4 --- [QA76] Medication or substance that is known to be an allergen without injury or harm Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm.... --PARENT--> [?] Circumstances associated with exposure to a drug, medicament or biological substance influencing the episode of care without injury or harm --EXCLUDES--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --- Walk 5 --- [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm Def: Incorrect dose - too high... --- Walk 6 --- [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm Def: Incorrect dose - too high...	[ "[8A80.Z] Migraine, unspecified\n --PARENT--> [8A80] Migraine\n Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a...\n --CHILD--> [8A80.1] Migraine with aura\n Def: Recurrent attacks, lasting minutes, of unilateral fully-reversible visual, sensory or other central nervous system symptoms that usually develop gradually and are usually followed by headache and asso...", "[8A80.Z] Migraine, unspecified\n --PARENT--> [8A80] Migraine\n Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a...\n --CHILD--> [8A80.0] Migraine without aura\n Def: Recurrent headache disorder manifesting in attacks lasting 4-72 hours. The duration of attacks may be shorter in children. Typical characteristics of the headache are unilateral location, pulsating qu...", "[QA76] Medication or substance that is known to be an allergen without injury or harm\n Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm....\n --PARENT--> [?] Circumstances associated with exposure to a drug, medicament or biological substance influencing the episode of care without injury or harm\n --PARENT--> [?] Health care related circumstances influencing the episode of care without injury or harm", "[QA76] Medication or substance that is known to be an allergen without injury or harm\n Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm....\n --PARENT--> [?] Circumstances associated with exposure to a drug, medicament or biological substance influencing the episode of care without injury or harm\n --EXCLUDES--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance", "[PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance\n --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm\n Def: Incorrect dose - too high...", "[PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance\n --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm\n Def: Incorrect dose - too high..." ]	8A80.Z	Migraine, unspecified	[ { "from_icd11": "8A80.Z", "icd10_code": "G43B0", "icd10_title": "Ophthalmoplegic migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43409", "icd10_title": "Hemiplegic migraine, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A0", "icd10_title": "Cyclical vomiting, in migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D0", "icd10_title": "Abdominal migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43709", "icd10_title": "Chronic migraine without aura, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A1", "icd10_title": "Cyclical vomiting, in migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43509", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43719", "icd10_title": "Chronic migraine without aura, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43501", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C0", "icd10_title": "Periodic headache syndromes in child or adult, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43401", "icd10_title": "Hemiplegic migraine, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43419", "icd10_title": "Hemiplegic migraine, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43B1", "icd10_title": "Ophthalmoplegic migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C1", "icd10_title": "Periodic headache syndromes in child or adult, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D1", "icd10_title": "Abdominal migraine, intractable" } ]	G43B0	Ophthalmoplegic migraine, not intractable
He was started on 2 g intravenous ceftriaxone daily, 500 mg intravenous metronidazole twice a day (BD), and 1.25 g intravenous vancomycin BD to cover MRSA. He underwent an MRI of his right groin, which reportedly demonstrated an enterocutaneous fistula, which bifurcated to two loops of the ileum. He then underwent surgical exploration, entry with right Rutherford Morrison incision into the abdominal cavity. There was no bowel adherent to the abdominal wall of the region of interest and no enteric fistula seen. Subcutaneous fat was dissected from the external oblique inferiorly to reach the sinus and further swabs were taken. The sinus was found to track to mesh, and mesh with incorporated muscle layers was excised. The resulting defect was closed in two layers with 0 nylon sutures. Peritoneal and muscle incisions were closed, stapled to the skin. The superficial sinus tract was debrided and left open with a capillary drain in situ. The patient recovered well postoperatively. The wound swab grew methicillin-sensitive Staphylococcus aureus (MSSA), and he was stepped down to oral cephalexin for a further 10 days. He was discharged after five days with drain removed prior to discharge, and community wound dressing management was recommended. His open wound was fully healed by secondary intention after three weeks. The patient was followed up seven months later and there was no recurrence of the hernia.	3.550781	0.98291	sec[1]/p[1]	en	0.999996	PMC8923242	https://doi.org/10.7759/cureus.22169	[ "intravenous", "sinus", "wound", "which", "fistula", "abdominal", "mesh", "muscle", "layers", "closed" ]	[ { "code": "QE11.Z", "title": "Hazardous drug use, unspecified" }, { "code": "PK91.16", "title": "Cardiovascular devices associated with injury or harm: peripheral venous catheter" }, { "code": "QE11.3", "title": "Hazardous use of cocaine" }, { "code": "JA61.5", "title": "Cerebral venous thrombosis in pregnancy" }, { "code": "8B22.1", "title": "Cerebral venous thrombosis" }, { "code": "CA0A.Z", "title": "Chronic rhinosinusitis, unspecified" }, { "code": "CA0Y&XA3523", "title": "Nasal sinus obstruction" }, { "code": "CA0J.Y", "title": "Other specified nasal polyp" }, { "code": "LB03.Y", "title": "Other specified structural developmental anomalies of umbilical cord" }, { "code": "DA09.61", "title": "Periapical abscess with sinus" } ]	=== ICD-11 CODES FOUND === [QE11.Z] Hazardous drug use, unspecified Also known as: Hazardous drug use, unspecified \| Hazardous drug use \| chronic drug use NOS \| chronic IV substance use \| drug use nos [PK91.16] Cardiovascular devices associated with injury or harm: peripheral venous catheter Also known as: Cardiovascular devices associated with injury or harm: peripheral venous catheter \| complication of intravenous line \| IV - [intravenous] line complication Excludes: Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm [QE11.3] Hazardous use of cocaine Definition: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health professionals. The increased risk may be from the frequency of cocaine use, from the amount used on a given occasion, from risky behaviours associated with cocaine use or the context of use, from a harmful route of administration, or from a combination of these. The risk may be related to short-term eff Also known as: Hazardous use of cocaine \| cocaine use \| intravenous cocaine use \| Hazardous use of crack cocaine \| crack cocaine use Excludes: Disorders due to use of cocaine [JA61.5] Cerebral venous thrombosis in pregnancy Also known as: Cerebral venous thrombosis in pregnancy \| Cerebrovenous sinus thrombosis in pregnancy \| cerebral venous thrombosis in pregnancy, unspecified trimester \| intracranial venous sinus thrombosis of pregnancy Includes: Cerebrovenous sinus thrombosis in pregnancy [8B22.1] Cerebral venous thrombosis Definition: Thrombosis (blood clot) of the cerebral venous sinuses, which drain blood from brain Also known as: Cerebral venous thrombosis \| nonpyogenic thrombosis of intracranial venous system \| nonpyogenic thrombophlebitis of intracranial venous sinus \| nonpyogenic thrombosis of intracranial venous sinus \| Nonpyogenic thrombosis of cerebral vein Excludes: Cerebral ischaemic stroke \| Cerebral venous thrombosis in the puerperium [CA0A.Z] Chronic rhinosinusitis, unspecified Also known as: Chronic rhinosinusitis, unspecified \| Chronic rhinosinusitis \| Chronic sinusitis \| chronic sinusitis NOS \| unspecified sinusitis [CA0J.Y] Other specified nasal polyp Also known as: Other specified nasal polyp \| Polyp of nasal cavity \| Polyp of the nasopharynx \| nasopharyngeal polyp \| Polyp of adenoid tissue [LB03.Y] Other specified structural developmental anomalies of umbilical cord Also known as: Other specified structural developmental anomalies of umbilical cord \| Umbilical cord calcifications \| Omphalomesenteric duct remnants or cysts \| Vitelline duct remnants and cysts \| Persistent omphalomesenteric duct [DA09.61] Periapical abscess with sinus Also known as: Periapical abscess with sinus \| Dental abscess with sinus \| Dentoalveolar abscess with sinus \| Dental sinus \| periapical abscess fistula Includes: Dental abscess with sinus \| Dentoalveolar abscess with sinus \| Dental sinus === GRAPH WALKS === --- Walk 1 --- [QE11.Z] Hazardous drug use, unspecified --PARENT--> [QE11] Hazardous drug use Def: A pattern of use of psychoactive substance(s) other than nicotine or alcohol that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent... --CHILD--> [QE11.0] Hazardous use of opioids Def: A pattern of opioid use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health profe... --- Walk 2 --- [QE11.Z] Hazardous drug use, unspecified --PARENT--> [QE11] Hazardous drug use Def: A pattern of use of psychoactive substance(s) other than nicotine or alcohol that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent... --CHILD--> [QE11.0] Hazardous use of opioids Def: A pattern of opioid use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health profe... --- Walk 3 --- [PK91.16] Cardiovascular devices associated with injury or harm: peripheral venous catheter --EXCLUDES--> [?] Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm --CHILD--> [?] Dislodgement, misconnection or de-attachment of a surgical or medical device without injury or harm Def: A device that has moved out of place, become disconnected, loosened or unstable, but without documented injury or harm.... --- Walk 4 --- [PK91.16] Cardiovascular devices associated with injury or harm: peripheral venous catheter --EXCLUDES--> [?] Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm --EXCLUDES--> [?] Mode of injury or harm associated with a surgical or other medical device, implant or graft --- Walk 5 --- [QE11.3] Hazardous use of cocaine Def: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health prof... --EXCLUDES--> [?] Disorders due to use of cocaine Def: Disorders due to use of cocaine are characterised by the pattern and consequences of cocaine use. Cocaine is a compound found in the leaves of the coca plant, Erythroxylum coca, which is indigenous to... --EXCLUDES--> [?] Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone Def: Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone are characterised by the pattern and consequences of use of these substances. There is a wide array of natur... --- Walk 6 --- [QE11.3] Hazardous use of cocaine Def: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health prof... --EXCLUDES--> [?] Disorders due to use of cocaine Def: Disorders due to use of cocaine are characterised by the pattern and consequences of cocaine use. Cocaine is a compound found in the leaves of the coca plant, Erythroxylum coca, which is indigenous to... --CHILD--> [?] Cocaine dependence Def: Cocaine dependence is a disorder of regulation of cocaine use arising from repeated or continuous use of cocaine. The characteristic feature is a strong internal drive to use cocaine, which is manifes...	[ "[QE11.Z] Hazardous drug use, unspecified\n --PARENT--> [QE11] Hazardous drug use\n Def: A pattern of use of psychoactive substance(s) other than nicotine or alcohol that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent...\n --CHILD--> [QE11.0] Hazardous use of opioids\n Def: A pattern of opioid use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health profe...", "[QE11.Z] Hazardous drug use, unspecified\n --PARENT--> [QE11] Hazardous drug use\n Def: A pattern of use of psychoactive substance(s) other than nicotine or alcohol that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent...\n --CHILD--> [QE11.0] Hazardous use of opioids\n Def: A pattern of opioid use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health profe...", "[PK91.16] Cardiovascular devices associated with injury or harm: peripheral venous catheter\n --EXCLUDES--> [?] Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm\n --CHILD--> [?] Dislodgement, misconnection or de-attachment of a surgical or medical device without injury or harm\n Def: A device that has moved out of place, become disconnected, loosened or unstable, but without documented injury or harm....", "[PK91.16] Cardiovascular devices associated with injury or harm: peripheral venous catheter\n --EXCLUDES--> [?] Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm\n --EXCLUDES--> [?] Mode of injury or harm associated with a surgical or other medical device, implant or graft", "[QE11.3] Hazardous use of cocaine\n Def: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health prof...\n --EXCLUDES--> [?] Disorders due to use of cocaine\n Def: Disorders due to use of cocaine are characterised by the pattern and consequences of cocaine use. Cocaine is a compound found in the leaves of the coca plant, Erythroxylum coca, which is indigenous to...\n --EXCLUDES--> [?] Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone\n Def: Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone are characterised by the pattern and consequences of use of these substances. There is a wide array of natur...", "[QE11.3] Hazardous use of cocaine\n Def: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health prof...\n --EXCLUDES--> [?] Disorders due to use of cocaine\n Def: Disorders due to use of cocaine are characterised by the pattern and consequences of cocaine use. Cocaine is a compound found in the leaves of the coca plant, Erythroxylum coca, which is indigenous to...\n --CHILD--> [?] Cocaine dependence\n Def: Cocaine dependence is a disorder of regulation of cocaine use arising from repeated or continuous use of cocaine. The characteristic feature is a strong internal drive to use cocaine, which is manifes..." ]	QE11.Z	Hazardous drug use, unspecified	[ { "from_icd11": "QE11.Z", "icd10_code": "Z722", "icd10_title": "" }, { "from_icd11": "PK91.16", "icd10_code": "T8242XA", "icd10_title": "Displacement of vascular dialysis catheter, initial encounter" }, { "from_icd11": "PK91.16", "icd10_code": "T8249XD", "icd10_title": "Other complication of vascular dialysis catheter, subsequent encounter" }, { "from_icd11": "PK91.16", "icd10_code": "T8243XA", "icd10_title": "Leakage of vascular dialysis catheter, initial encounter" }, { "from_icd11": "PK91.16", "icd10_code": "T824", "icd10_title": "Mechanical complication of vascular dialysis catheter" }, { "from_icd11": "JA61.5", "icd10_code": "O2251", "icd10_title": "Cerebral venous thrombosis in pregnancy, first trimester" }, { "from_icd11": "JA61.5", "icd10_code": "O2252", "icd10_title": "Cerebral venous thrombosis in pregnancy, second trimester" }, { "from_icd11": "JA61.5", "icd10_code": "O2253", "icd10_title": "Cerebral venous thrombosis in pregnancy, third trimester" }, { "from_icd11": "JA61.5", "icd10_code": "O225", "icd10_title": "Cerebral venous thrombosis in pregnancy" }, { "from_icd11": "8B22.1", "icd10_code": "G08", "icd10_title": "Intracranial and intraspinal phlebitis and thrombophlebitis" }, { "from_icd11": "8B22.1", "icd10_code": "I676", "icd10_title": "Nonpyogenic thrombosis of intracranial venous system" }, { "from_icd11": "8B22.1", "icd10_code": "I636", "icd10_title": "Cerebral infarction due to cerebral venous thrombosis, nonpyogenic" }, { "from_icd11": "CA0A.Z", "icd10_code": "J329", "icd10_title": "Chronic sinusitis, unspecified" }, { "from_icd11": "CA0A.Z", "icd10_code": "J324", "icd10_title": "Chronic pansinusitis" }, { "from_icd11": "CA0A.Z", "icd10_code": "J320", "icd10_title": "Chronic maxillary sinusitis" } ]	Z722
The patient came to our facility via EMS as a stroke alert around 06:00. Her last known normal (LKN) was determined to be 22:30 the previous night. On arrival, her blood pressure was 150/80, her blood glucose level was 101 mg/dL, her heart rate was in the 70s (beats per minute), and there was active AF with a right bundle branch block on electrocardiogram. She reported no pain she was afebrile. National Institutes of Health Stroke Scale (NIHSS) was 1 for mild dysarthria; no motor deficits or weakness was appreciated on her initial examination. Glasgow Coma Scale (GCS) was 15, fully alert and oriented. Her pupils were equal and reactive on both sides. Modified Rankin Scale (mRS) score was 1. Echocardiogram reveal an ejection fraction of 55-60%, bubble study was negative and no shunt was noted with contrast study. On basic labs, her white blood cell count was 5.55 k/cmm, hemoglobin 11 gm/dL and platelets were 240 k/cmm. Potassium was 4.5 mEq/L, sodium levels were 135 mEq/L, creatinine was 0.91 mg/dL. Other basic labs were unremarkable. Urine analysis was negative. Patient denied diarrhea or constipation. Patient reported mild nausea which she thought was due to the lunch she had that day. The immediate CT of the head was reported as normal. A CT angiogram of the head and neck revealed an occlusion of the distal basilar artery with a cerebral perfusion deficit of the right superior cerebellar artery .	3.708984	0.985352	sec[1]/p[1]	en	0.999997	PMC10381099	https://doi.org/10.7759/cureus.41096	[ "blood", "scale", "stroke", "alert", "basic", "labs", "head", "artery", "came", "facility" ]	[ { "code": "3C0Z", "title": "Diseases of the blood or blood-forming organs, unspecified" }, { "code": "MF50.4Z", "title": "Haematuria, unspecified" }, { "code": "MA12.1", "title": "Finding of cocaine in blood" }, { "code": "MA12.4", "title": "Finding of steroid agent in blood" }, { "code": "MA12.2", "title": "Finding of hallucinogen in blood" }, { "code": "ME66.1", "title": "Changes in skin texture" }, { "code": "5C53.2Y", "title": "Other specified disorders of mitochondrial oxidative phosphorylation" }, { "code": "ME63.4", "title": "Chronic scaling or hyperkeratotic skin disorder" }, { "code": "MB20.1", "title": "Coma" }, { "code": "MB20.1&XC87", "title": "Glasgow Coma Scale, eyes opening, never" } ]	=== ICD-11 CODES FOUND === [3C0Z] Diseases of the blood or blood-forming organs, unspecified Also known as: Diseases of the blood or blood-forming organs, unspecified \| Blood, lymph or spleen disease \| blood condition NOS \| blood disorder NOS \| bone marrow disease NOS [MF50.4Z] Haematuria, unspecified Also known as: Haematuria, unspecified \| Haematuria \| blood in urine \| urinary blood \| haematuria NOS [MA12.1] Finding of cocaine in blood Also known as: Finding of cocaine in blood \| cocaine in blood [MA12.4] Finding of steroid agent in blood Also known as: Finding of steroid agent in blood \| steroid in blood [MA12.2] Finding of hallucinogen in blood Also known as: Finding of hallucinogen in blood \| hallucinogen in blood [ME66.1] Changes in skin texture Definition: Alterations in skin texture of unspecified cause. Also known as: Changes in skin texture \| Skin textural disturbance \| Thickening of skin \| induration of skin \| Skin sclerosis [5C53.2Y] Other specified disorders of mitochondrial oxidative phosphorylation Also known as: Other specified disorders of mitochondrial oxidative phosphorylation \| Mitochondrial oxidative phosphorylation disorders due to mitochondrial DNA anomalies \| Respiratory chain disorders caused by mutations of mtDNA \| OXPHOS - [oxidative phosphorylation] diseases due to mtDNA anomalies \| Proximal tubulopathy - diabetes mellitus - cerebellar ataxia [ME63.4] Chronic scaling or hyperkeratotic skin disorder Definition: A provisional diagnosis for a chronic skin disorder of unknown or uncertain nature in which scaling and hyperkeratosis are prominent features. Examples include psoriasis, ichthyoses, small plaque parapsoriasis and mycosis fungoides. Also known as: Chronic scaling or hyperkeratotic skin disorder [MB20.1] Coma Definition: Acute state lasting more than one hour and usually less than a month. The comatose patient is unresponsive, lying with their eyes closed and cannot be aroused even by vigorous and noxious stimuli. Motor responses to noxious stimulation are limited to reflexive behaviour. Etiologies include but are not limited to traumatic, anoxic, infectious, neoplastic, vascular, inflammatory and metabolic brain injuries. Also known as: Coma \| comatose \| exanimation \| Coma, NOS \| Unconsciousness, NOS Excludes: Diabetic coma \| Hepatic coma \| Neonatal coma === GRAPH WALKS === --- Walk 1 --- [3C0Z] Diseases of the blood or blood-forming organs, unspecified --PARENT--> [03] Diseases of the blood or blood-forming organs Def: This chapter includes diseases of the blood as well as diseases of blood forming organs.... --EXCLUDES--> [?] Pregnancy, childbirth or the puerperium Def: A group of conditions characterised as occurring during the period of time from conception to delivery (pregnancy), during labour and delivery (childbirth) or during the approximately six weeks after ... --- Walk 2 --- [3C0Z] Diseases of the blood or blood-forming organs, unspecified --PARENT--> [03] Diseases of the blood or blood-forming organs Def: This chapter includes diseases of the blood as well as diseases of blood forming organs.... --EXCLUDES--> [?] Pregnancy, childbirth or the puerperium Def: A group of conditions characterised as occurring during the period of time from conception to delivery (pregnancy), during labour and delivery (childbirth) or during the approximately six weeks after ... --- Walk 3 --- [MF50.4Z] Haematuria, unspecified --PARENT--> [MF50.4] Haematuria Def: Hematuria means presence of blood or red blood cells (RBCs) in the urine. There are two types of hematuria: gross hematuria (when one can see the blood in the urine) and microscopic hematuria (when th... --CHILD--> [MF50.4Z] Haematuria, unspecified --- Walk 4 --- [MF50.4Z] Haematuria, unspecified --PARENT--> [MF50.4] Haematuria Def: Hematuria means presence of blood or red blood cells (RBCs) in the urine. There are two types of hematuria: gross hematuria (when one can see the blood in the urine) and microscopic hematuria (when th... --CHILD--> [MF50.4Z] Haematuria, unspecified --- Walk 5 --- [MA12.1] Finding of cocaine in blood --PARENT--> [MA12] Clinical findings of drugs, medicaments and biological substances in blood, blood-forming organs, or the immune system --CHILD--> [MA12.2] Finding of hallucinogen in blood --- Walk 6 --- [MA12.1] Finding of cocaine in blood --PARENT--> [MA12] Clinical findings of drugs, medicaments and biological substances in blood, blood-forming organs, or the immune system --CHILD--> [MA12.2] Finding of hallucinogen in blood	[ "[3C0Z] Diseases of the blood or blood-forming organs, unspecified\n --PARENT--> [03] Diseases of the blood or blood-forming organs\n Def: This chapter includes diseases of the blood as well as diseases of blood forming organs....\n --EXCLUDES--> [?] Pregnancy, childbirth or the puerperium\n Def: A group of conditions characterised as occurring during the period of time from conception to delivery (pregnancy), during labour and delivery (childbirth) or during the approximately six weeks after ...", "[3C0Z] Diseases of the blood or blood-forming organs, unspecified\n --PARENT--> [03] Diseases of the blood or blood-forming organs\n Def: This chapter includes diseases of the blood as well as diseases of blood forming organs....\n --EXCLUDES--> [?] Pregnancy, childbirth or the puerperium\n Def: A group of conditions characterised as occurring during the period of time from conception to delivery (pregnancy), during labour and delivery (childbirth) or during the approximately six weeks after ...", "[MF50.4Z] Haematuria, unspecified\n --PARENT--> [MF50.4] Haematuria\n Def: Hematuria means presence of blood or red blood cells (RBCs) in the urine. There are two types of hematuria: gross hematuria (when one can see the blood in the urine) and microscopic hematuria (when th...\n --CHILD--> [MF50.4Z] Haematuria, unspecified", "[MF50.4Z] Haematuria, unspecified\n --PARENT--> [MF50.4] Haematuria\n Def: Hematuria means presence of blood or red blood cells (RBCs) in the urine. There are two types of hematuria: gross hematuria (when one can see the blood in the urine) and microscopic hematuria (when th...\n --CHILD--> [MF50.4Z] Haematuria, unspecified", "[MA12.1] Finding of cocaine in blood\n --PARENT--> [MA12] Clinical findings of drugs, medicaments and biological substances in blood, blood-forming organs, or the immune system\n --CHILD--> [MA12.2] Finding of hallucinogen in blood", "[MA12.1] Finding of cocaine in blood\n --PARENT--> [MA12] Clinical findings of drugs, medicaments and biological substances in blood, blood-forming organs, or the immune system\n --CHILD--> [MA12.2] Finding of hallucinogen in blood" ]	3C0Z	Diseases of the blood or blood-forming organs, unspecified	[ { "from_icd11": "3C0Z", "icd10_code": "D75A", "icd10_title": "Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia" }, { "from_icd11": "3C0Z", "icd10_code": "D7581", "icd10_title": "Myelofibrosis" }, { "from_icd11": "3C0Z", "icd10_code": "D7582", "icd10_title": "Heparin induced thrombocytopenia (HIT)" }, { "from_icd11": "3C0Z", "icd10_code": "D7589", "icd10_title": "Other specified diseases of blood and blood-forming organs" }, { "from_icd11": "3C0Z", "icd10_code": "D759", "icd10_title": "Disease of blood and blood-forming organs, unspecified" }, { "from_icd11": "3C0Z", "icd10_code": "D763", "icd10_title": "Other histiocytosis syndromes" }, { "from_icd11": "3C0Z", "icd10_code": "Q899", "icd10_title": "Congenital malformation, unspecified" }, { "from_icd11": "3C0Z", "icd10_code": "III", "icd10_title": "" }, { "from_icd11": "3C0Z", "icd10_code": "D70-D77", "icd10_title": "" }, { "from_icd11": "3C0Z", "icd10_code": "D75", "icd10_title": "Other and unspecified diseases of blood and blood-forming organs" }, { "from_icd11": "3C0Z", "icd10_code": "D77", "icd10_title": "Other disorders of blood and blood-forming organs in diseases classified elsewhere" }, { "from_icd11": "3C0Z", "icd10_code": "D758", "icd10_title": "Other specified diseases of blood and blood-forming organs" }, { "from_icd11": "3C0Z", "icd10_code": "D76", "icd10_title": "Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue" }, { "from_icd11": "MF50.4Z", "icd10_code": "R310", "icd10_title": "Gross hematuria" }, { "from_icd11": "MF50.4Z", "icd10_code": "R312", "icd10_title": "Other microscopic hematuria" } ]	D75A	Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia
Although the MCED test, as well as CA-19-9 and CEA, were not indicative of cancer in this patient, this is not surprising given that these biomarkers have suboptimal sensitivity and, thus, a relatively high percentage of cases are false negatives ( 6 , 9 ). Conversely, the ExoVita test has shown high sensitivity ( 12 ) for PDAC at stages 1 and 2. The ExoVita test, combined with the presence of germline mutations in KRAS and TP53 genes, indicated high risk of developing cancer in this patient. After careful consideration of the test results and multiple differing surgical opinions, the patient elected to undergo a robotic pancreaticoduodenectomy (Whipple) procedure. Final pathology of the resected pancreatic tissue revealed the presence of an intraductal papillary mucinous neoplasm (IPMN) of pancreatobiliary type with focal high-grade dysplasia primarily involving the main duct (MD-IPMN) with extension into a branch duct (BD-IPMN) in addition to high-grade PanIN, none of which had not been detected by previous multiple imaging modalities. The patient’s post-operative course was unremarkable. At five months status post Whipple procedure, the patient continues to recover well without complications. In addition, a repeat of the ExoVita test indicated low probability of cancer with all biomarkers expressed from exosomes appropriately declined. The patient’s two ExoVita results are reported in Figure 2 .	4.054688	0.83252	sec[2]/p[3]	en	0.999998	PMC10210587	https://doi.org/10.3389/fonc.2023.1170513	[ "exovita", "cancer", "this", "ipmn", "well", "biomarkers", "sensitivity", "presence", "multiple", "whipple" ]	[ { "code": "2D4Z", "title": "Unspecified malignant neoplasms of unspecified sites" }, { "code": "2C0Z", "title": "Malignant neoplasms of intestine, unspecified" }, { "code": "2B5Z", "title": "Malignant mesenchymal neoplasm of unspecified type" }, { "code": "2E2Z", "title": "Malignant neoplasm metastasis, unspecified" }, { "code": "2D42", "title": "Malignant neoplasms of ill-defined sites" }, { "code": "4A01.03", "title": "Transient hypogammaglobulinaemia of infancy" }, { "code": "EB30", "title": "Eosinophilic cellulitis" }, { "code": "QC2Y", "title": "Other specified contact with health services associated with the health of others" }, { "code": "4A60.1", "title": "Cryopyrin-associated periodic syndromes" }, { "code": "2D10.0", "title": "Follicular carcinoma of thyroid gland" } ]	=== ICD-11 CODES FOUND === [2D4Z] Unspecified malignant neoplasms of unspecified sites Also known as: Unspecified malignant neoplasms of unspecified sites \| malignancy of unspecified site \| malignancy unspecified primary site \| malignant growth of unspecified site \| malignant mass of unspecified site [2C0Z] Malignant neoplasms of intestine, unspecified Also known as: Malignant neoplasms of intestine, unspecified \| cancer of intestine \| malignant neoplasm of intestine NOS \| malignant tumour of intestine NOS \| intestinal cancer NOS [2B5Z] Malignant mesenchymal neoplasm of unspecified type Also known as: Malignant mesenchymal neoplasm of unspecified type \| calvarium cancer \| ethmoid bone cancer \| facial bone cancer \| frontal bone cancer [2E2Z] Malignant neoplasm metastasis, unspecified Also known as: Malignant neoplasm metastasis, unspecified \| secondary malignant neoplasm \| metastasis \| metastases \| disseminated metastases [2D42] Malignant neoplasms of ill-defined sites Definition: Malignant neoplasms of ill defined sites is used for cases where the documentation refers to a site that includes multiple organ systems and tissue types that should be coded separately. Also known as: Malignant neoplasms of ill-defined sites \| Malignant neoplasm of ill-defined site of head, face or neck \| Malignant neoplasm of nose NOS \| Primary malignant neoplasm of cheek \| malignant neoplasm of cheek NOS [4A01.03] Transient hypogammaglobulinaemia of infancy Also known as: Transient hypogammaglobulinaemia of infancy \| immunoglobulin maturational delay \| THI - [transient hypogammaglobulinaemia of infancy] [EB30] Eosinophilic cellulitis Definition: Eosinophilic cellulitis (Wells syndrome) is characterised by a distinctive clinical picture resembling cellulitis, and a typical histology with tissue eosinophilia, oedema and ‘flame’ figures (clusters of eosinophils and histiocytes around a core of collagen and eosinophilic debris). It can affect either sex, usually in adult life. Any site may be involved, with single or multiple lesions, and recurrences are common. Initially, the lesions are itchy erythematous plaques with features resembling Also known as: Eosinophilic cellulitis \| Wells' syndrome [QC2Y] Other specified contact with health services associated with the health of others Also known as: Other specified contact with health services associated with the health of others \| Boarder in health-care facility other than healthy person accompanying sick person \| Health supervision or care of other healthy infant or child \| child in care \| healthy infant receiving care [4A60.1] Cryopyrin-associated periodic syndromes Definition: CAPS is an autoinflammatory disease associated with gain of function changes in the cryopyrin protein, resulting in inflammasome activation and enhanced IL1 beta production. This results in clinical signs and symptoms of inflammation in the form of rash, fever, joint and eye symptoms with increased acute phase reactants. Also known as: Cryopyrin-associated periodic syndromes \| CAPS - [Cryopyrin-associated periodic syndromes] \| Cryopyrinopathies \| Chronic infantile neurological, cutaneous and articular syndrome \| Infantile-onset multisystem inflammatory disease Includes: Cryopyrinopathies [2D10.0] Follicular carcinoma of thyroid gland Definition: A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. The nuclear features which characterise the thyroid gland papillary carcinoma are absent. Radiation exposure is a risk factor and it comprises approximately 10% to 15% of thyroid cancers. Clinically, it usually presents as a solitary mass in the thyroid gland. It is generally unifocal and thickly encapsulated and shows invasion of the capsule or the vessels. Diagnostic procedures include: thyroid ultrasound a Also known as: Follicular carcinoma of thyroid gland \| follicular carcinoma of unspecified site \| follicular thyroid carcinoma \| moderately differentiated follicular carcinoma of thyroid gland \| pure follicle carcinoma of thyroid gland === GRAPH WALKS === --- Walk 1 --- [2D4Z] Unspecified malignant neoplasms of unspecified sites --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites --CHILD--> [2D42] Malignant neoplasms of ill-defined sites Def: Malignant neoplasms of ill defined sites is used for cases where the documentation refers to a site that includes multiple organ systems and tissue types that should be coded separately.... --- Walk 2 --- [2D4Z] Unspecified malignant neoplasms of unspecified sites --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites --CHILD--> [2D40] Adenocarcinoma of unspecified site Def: A common cancer characterised by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to ... --- Walk 3 --- [2C0Z] Malignant neoplasms of intestine, unspecified --PARENT--> [?] Malignant neoplasms of intestine --CHILD--> [?] Malignant neoplasms of large intestine --- Walk 4 --- [2C0Z] Malignant neoplasms of intestine, unspecified --PARENT--> [?] Malignant neoplasms of intestine --EXCLUDES--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --- Walk 5 --- [2B5Z] Malignant mesenchymal neoplasm of unspecified type --PARENT--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --PARENT--> [?] Malignant neoplasms, stated or presumed to be primary, of specified sites, except of lymphoid, haematopoietic, central nervous system or related tissues --- Walk 6 --- [2B5Z] Malignant mesenchymal neoplasm of unspecified type --PARENT--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --CHILD--> [2B50] Chondrosarcoma, primary site	[ "[2D4Z] Unspecified malignant neoplasms of unspecified sites\n --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites\n --CHILD--> [2D42] Malignant neoplasms of ill-defined sites\n Def: Malignant neoplasms of ill defined sites is used for cases where the documentation refers to a site that includes multiple organ systems and tissue types that should be coded separately....", "[2D4Z] Unspecified malignant neoplasms of unspecified sites\n --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites\n --CHILD--> [2D40] Adenocarcinoma of unspecified site\n Def: A common cancer characterised by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to ...", "[2C0Z] Malignant neoplasms of intestine, unspecified\n --PARENT--> [?] Malignant neoplasms of intestine\n --CHILD--> [?] Malignant neoplasms of large intestine", "[2C0Z] Malignant neoplasms of intestine, unspecified\n --PARENT--> [?] Malignant neoplasms of intestine\n --EXCLUDES--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...", "[2B5Z] Malignant mesenchymal neoplasm of unspecified type\n --PARENT--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...\n --PARENT--> [?] Malignant neoplasms, stated or presumed to be primary, of specified sites, except of lymphoid, haematopoietic, central nervous system or related tissues", "[2B5Z] Malignant mesenchymal neoplasm of unspecified type\n --PARENT--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...\n --CHILD--> [2B50] Chondrosarcoma, primary site" ]	2D4Z	Unspecified malignant neoplasms of unspecified sites	[ { "from_icd11": "2D4Z", "icd10_code": "C802", "icd10_title": "Malignant neoplasm associated with transplanted organ" }, { "from_icd11": "2D4Z", "icd10_code": "C7650", "icd10_title": "Malignant neoplasm of unspecified lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7642", "icd10_title": "Malignant neoplasm of left upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7640", "icd10_title": "Malignant neoplasm of unspecified upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7652", "icd10_title": "Malignant neoplasm of left lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7651", "icd10_title": "Malignant neoplasm of right lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7641", "icd10_title": "Malignant neoplasm of right upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C801", "icd10_title": "Malignant (primary) neoplasm, unspecified" }, { "from_icd11": "2D4Z", "icd10_code": "C768", "icd10_title": "Malignant neoplasm of other specified ill-defined sites" }, { "from_icd11": "2D4Z", "icd10_code": "C761", "icd10_title": "Malignant neoplasm of thorax" }, { "from_icd11": "2D4Z", "icd10_code": "C762", "icd10_title": "Malignant neoplasm of abdomen" }, { "from_icd11": "2D4Z", "icd10_code": "C763", "icd10_title": "Malignant neoplasm of pelvis" }, { "from_icd11": "2D4Z", "icd10_code": "C800", "icd10_title": "Disseminated malignant neoplasm, unspecified" }, { "from_icd11": "2D4Z", "icd10_code": "C76-C80", "icd10_title": "" }, { "from_icd11": "2D4Z", "icd10_code": "C76", "icd10_title": "Malignant neoplasm of other and ill-defined sites" } ]	C802	Malignant neoplasm associated with transplanted organ
Our patient was a 65-year-old female with a medical history of myotonic dystrophy, deep vein thrombosis on chronic anticoagulation, ulcerative colitis, and breast lobular carcinoma two years status post left mastectomy and radiation therapy. Her previous breast cancer was estrogen receptor (ER) positive, progesterone receptor (PR) negative, and human epidermal growth factor receptor 2 (HER2) negative. Family history was significant for a mother who had breast cancer. She presented with complaints of heart palpitations, fatigue, and an unintentional 30-pound weight loss over four months. In addition, she had been experiencing severe reflux limiting oral intake for the past four months. Computed tomography imaging of the abdomen and pelvis demonstrated new trace volume pelvic ascites with peritoneal nodularity, new omental fat stranding suggestive of edema and caking, new osseous sclerotic lesions concerning for metastatic disease, and thickening of the stomach wall . Due to elevated tumor marker levels, CT findings, and weight loss, the patient underwent esophagogastroduodenoscopy (EGD) with endoscopic ultrasound (EUS). The EGD revealed Los Angeles (LA) grade C erosive esophagitis and inflamed gastric mucosa. Mucosal biopsies were taken and sent to pathology. The EUS identified several enlarged lymph nodes in the aortopulmonary region, and stomach wall thickness was measured at approximately 20 mm .	3.894531	0.984375	sec[1]/p[0]	en	0.999997	PMC10341378	https://doi.org/10.7759/cureus.40371	[ "breast", "receptor", "cancer", "weight", "loss", "four", "stomach", "wall", "myotonic", "dystrophy" ]	[ { "code": "GB23", "title": "Certain specified disorders of breast" }, { "code": "GB21.Z", "title": "Inflammatory disorders of breast, unspecified" }, { "code": "GB21.Y", "title": "Other specified inflammatory disorders of breast" }, { "code": "QF01.0", "title": "Acquired absence of breast" }, { "code": "GB23.3", "title": "Atrophy of breast" }, { "code": "5A61.0", "title": "Hypopituitarism" }, { "code": "4A01.0Y", "title": "Other specified immunodeficiencies with predominantly antibody defects" }, { "code": "LD2A.4", "title": "46,XY disorder of sex development due to androgen resistance" }, { "code": "LD24.04", "title": "Chondrodysplasia punctata" }, { "code": "4A00.Y", "title": "Other specified primary immunodeficiencies due to disorders of innate immunity" } ]	=== ICD-11 CODES FOUND === [GB23] Certain specified disorders of breast Definition: Any disorder of the breast or breast tissue, characterised by pathological changes, not classified elsewhere. Also known as: Certain specified disorders of breast \| disease of breast \| mastopathy [GB21.Z] Inflammatory disorders of breast, unspecified Also known as: Inflammatory disorders of breast, unspecified \| Inflammatory disorders of breast \| breast inflammation \| inflammatory breast disease \| mastitis NOS [GB21.Y] Other specified inflammatory disorders of breast Also known as: Other specified inflammatory disorders of breast \| Breast antibioma \| Infective mastitis \| acute infective mastitis \| nonpuerperal infective mastitis [QF01.0] Acquired absence of breast Also known as: Acquired absence of breast \| absence of breast \| mastectomy status \| Acquired absence of breast, partial \| Acquired absence of breast, total [GB23.3] Atrophy of breast Definition: A condition of the breast, caused by apoptosis of the cells commonly due to prolonged estrogen reduction, diminished cellular proliferation, decreased cellular volume, decreased function, ischaemia, malnutrition, disease, or mutation. This condition is characterised by a partial or complete decrease in size and function of the breast tissue. Also known as: Atrophy of breast \| Hypoplasia of breast \| hypoplastic breast \| mammary hypoplasia [5A61.0] Hypopituitarism Definition: A disorder manifesting a deficiency or decrease of one or more pituitary hormones, which is caused by a variety of diseases such as tumour, trauma/surgery, irradiation, inflammation and haemorrhage/infarction. Also known as: Hypopituitarism \| subpituitarism \| hypophyseal dystrophy \| hypohypophysism \| anterior pituitary insufficiency (in part) Includes: pituitary cachexia \| pituitary short stature [4A01.0Y] Other specified immunodeficiencies with predominantly antibody defects Also known as: Other specified immunodeficiencies with predominantly antibody defects \| Common variable immunodeficiency \| B-cell activating factor receptor deficiency \| BAFF - [ B-cell activating factor] receptor deficiency \| Cluster of differentiation 19 deficiency [LD2A.4] 46,XY disorder of sex development due to androgen resistance Definition: Androgen insensitivity syndrome (AIS) is a disorder of sex development (DSD) characterised by the presence of female external genitalia, ambiguous genitalia or variable defects in virilization in a 46,XY individual with absent or partial responsiveness to age-appropriate levels of androgens. It comprises two clinical subgroups: complete AIS (CAIS) and partial AIS (PAIS). Also known as: 46,XY disorder of sex development due to androgen resistance \| Androgen resistance syndrome \| Testicular feminization syndrome \| Androgen insensitivity syndrome \| Goldberg-Maxwell syndrome [LD24.04] Chondrodysplasia punctata Also known as: Chondrodysplasia punctata \| chondrodysplasia punctata (stippled epiphyses) group \| chondrodysplasia punctata congenita \| dysplasia punctata epiphysis \| dysplasia punctata [4A00.Y] Other specified primary immunodeficiencies due to disorders of innate immunity Also known as: Other specified primary immunodeficiencies due to disorders of innate immunity \| Autoinflammatory syndromes with immunodeficiency \| Autoinflammatory disease due to interleukin-1 receptor antagonist deficiency \| Sterile multifocal osteomyelitis with periostitis and pustulosis \| Deficiency of interleukin 1 receptor antagonist === GRAPH WALKS === --- Walk 1 --- [GB23] Certain specified disorders of breast Def: Any disorder of the breast or breast tissue, characterised by pathological changes, not classified elsewhere.... --PARENT--> [?] Disorders of breast Def: Any disorder characterised by pathological changes to the breast or breast tissue.... --CHILD--> [GB22] Hypertrophy of breast Def: A condition affecting the breast, characterised by unilateral or bilateral enlargement or thickening of the connective tissues that exceeds 3% of the total body weight. This condition may be associate... --- Walk 2 --- [GB23] Certain specified disorders of breast Def: Any disorder of the breast or breast tissue, characterised by pathological changes, not classified elsewhere.... --PARENT--> [?] Disorders of breast Def: Any disorder characterised by pathological changes to the breast or breast tissue.... --EXCLUDES--> [?] Certain specified disorders of breast or lactation associated with childbirth --- Walk 3 --- [GB21.Z] Inflammatory disorders of breast, unspecified --PARENT--> [GB21] Inflammatory disorders of breast Def: Any disorder of the breast or breast tissue, characterised by inflammatory effects, pain, heat, redness, swelling, and loss of function.... --RELATED_TO--> [?] Nonpurulent mastitis associated with childbirth --- Walk 4 --- [GB21.Z] Inflammatory disorders of breast, unspecified --PARENT--> [GB21] Inflammatory disorders of breast Def: Any disorder of the breast or breast tissue, characterised by inflammatory effects, pain, heat, redness, swelling, and loss of function.... --CHILD--> [GB21.0] Breast abscess Def: A condition of the breast, caused by inflammation due to infection with a bacterial or parasitic host, or contact with other foreign materials. This condition is characterised by a focal accumulation ... --- Walk 5 --- [GB21.Y] Other specified inflammatory disorders of breast --PARENT--> [GB21] Inflammatory disorders of breast Def: Any disorder of the breast or breast tissue, characterised by inflammatory effects, pain, heat, redness, swelling, and loss of function.... --CHILD--> [GB21.Y] Other specified inflammatory disorders of breast --- Walk 6 --- [GB21.Y] Other specified inflammatory disorders of breast --PARENT--> [GB21] Inflammatory disorders of breast Def: Any disorder of the breast or breast tissue, characterised by inflammatory effects, pain, heat, redness, swelling, and loss of function.... --RELATED_TO--> [?] Nonpurulent mastitis associated with childbirth	[ "[GB23] Certain specified disorders of breast\n Def: Any disorder of the breast or breast tissue, characterised by pathological changes, not classified elsewhere....\n --PARENT--> [?] Disorders of breast\n Def: Any disorder characterised by pathological changes to the breast or breast tissue....\n --CHILD--> [GB22] Hypertrophy of breast\n Def: A condition affecting the breast, characterised by unilateral or bilateral enlargement or thickening of the connective tissues that exceeds 3% of the total body weight. This condition may be associate...", "[GB23] Certain specified disorders of breast\n Def: Any disorder of the breast or breast tissue, characterised by pathological changes, not classified elsewhere....\n --PARENT--> [?] Disorders of breast\n Def: Any disorder characterised by pathological changes to the breast or breast tissue....\n --EXCLUDES--> [?] Certain specified disorders of breast or lactation associated with childbirth", "[GB21.Z] Inflammatory disorders of breast, unspecified\n --PARENT--> [GB21] Inflammatory disorders of breast\n Def: Any disorder of the breast or breast tissue, characterised by inflammatory effects, pain, heat, redness, swelling, and loss of function....\n --RELATED_TO--> [?] Nonpurulent mastitis associated with childbirth", "[GB21.Z] Inflammatory disorders of breast, unspecified\n --PARENT--> [GB21] Inflammatory disorders of breast\n Def: Any disorder of the breast or breast tissue, characterised by inflammatory effects, pain, heat, redness, swelling, and loss of function....\n --CHILD--> [GB21.0] Breast abscess\n Def: A condition of the breast, caused by inflammation due to infection with a bacterial or parasitic host, or contact with other foreign materials. This condition is characterised by a focal accumulation ...", "[GB21.Y] Other specified inflammatory disorders of breast\n --PARENT--> [GB21] Inflammatory disorders of breast\n Def: Any disorder of the breast or breast tissue, characterised by inflammatory effects, pain, heat, redness, swelling, and loss of function....\n --CHILD--> [GB21.Y] Other specified inflammatory disorders of breast", "[GB21.Y] Other specified inflammatory disorders of breast\n --PARENT--> [GB21] Inflammatory disorders of breast\n Def: Any disorder of the breast or breast tissue, characterised by inflammatory effects, pain, heat, redness, swelling, and loss of function....\n --RELATED_TO--> [?] Nonpurulent mastitis associated with childbirth" ]	GB23	Certain specified disorders of breast	[ { "from_icd11": "GB23", "icd10_code": "N6459", "icd10_title": "Other signs and symptoms in breast" }, { "from_icd11": "GB23", "icd10_code": "N6489", "icd10_title": "Other specified disorders of breast" }, { "from_icd11": "GB23", "icd10_code": "N6481", "icd10_title": "Ptosis of breast" }, { "from_icd11": "GB23", "icd10_code": "N6482", "icd10_title": "Hypoplasia of breast" }, { "from_icd11": "GB23", "icd10_code": "N6452", "icd10_title": "Nipple discharge" }, { "from_icd11": "GB23", "icd10_code": "N6451", "icd10_title": "Induration of breast" }, { "from_icd11": "GB23", "icd10_code": "N6453", "icd10_title": "Retraction of nipple" }, { "from_icd11": "GB23", "icd10_code": "N64", "icd10_title": "Other disorders of breast" }, { "from_icd11": "GB23", "icd10_code": "N648", "icd10_title": "Other specified disorders of breast" }, { "from_icd11": "GB23", "icd10_code": "N645", "icd10_title": "Other signs and symptoms in breast" }, { "from_icd11": "GB21.Z", "icd10_code": "N610", "icd10_title": "Mastitis without abscess" }, { "from_icd11": "GB21.Z", "icd10_code": "N611", "icd10_title": "Abscess of the breast and nipple" }, { "from_icd11": "GB21.Z", "icd10_code": "N61", "icd10_title": "Inflammatory disorders of breast" }, { "from_icd11": "QF01.0", "icd10_code": "Z9012", "icd10_title": "Acquired absence of left breast and nipple" }, { "from_icd11": "QF01.0", "icd10_code": "Z9011", "icd10_title": "Acquired absence of right breast and nipple" } ]	N6459	Other signs and symptoms in breast
In our case study, the infant was febrile, with elevated CRP. It was presumably not contamination since the infant was symptomatic, and S. salivarius was isolated in two consecutive cultures done at different sites each time. This sufficiently proves that Gram‐positive cocci are not always GBS, and VGS, though rare, should not be neglected because of its life‐threatening complications in some pediatric cases, including endocarditis and meningitis. 6 , 7 In response, LP was also performed at admission to rule out early‐onset meningitis, and bedside heart ultrasound showed normal heart structure with good left ventricular function and no vegetation, which ruled out endocarditis. In addition to these complications, it is noteworthy that S. salivarius , in our case, was also multi‐resistant and susceptible to only vancomycin, which proves that not all streptococci are susceptible to the first‐line antibiotics for neonatal sepsis. Prospective study of Corredoira et al. showed that S. salivarius had the greatest rate of resistance amongst the VGS to penicillin with 32%, in contrast to S. bovis , which were all susceptible to penicillin. 10 In our case, upon receiving the primary report of Gram‐positive cocci, we initially kept our broad‐spectrum conventional antibiotics aiming for GBS; however, the outcome was not profitable. Therefore, vancomycin was used instead for 10 days, which showed a good result.	4.121094	0.827148	sec[2]/p[3]	en	0.999997	PMC9834522	https://doi.org/10.1002/ccr3.6837	[ "that", "which", "salivarius", "susceptible", "proves", "gram", "cocci", "complications", "endocarditis", "meningitis" ]	[ { "code": "8A80.Z", "title": "Migraine, unspecified" }, { "code": "QA76", "title": "Medication or substance that is known to be an allergen without injury or harm" }, { "code": "PL13.6", "title": "Medication or substance that is known to be an allergen, as mode of injury or harm" }, { "code": "9C40.A0", "title": "Papilloedema" }, { "code": "PA6Z", "title": "Unintentional fall from unspecified height" }, { "code": "BD50.41", "title": "Abdominal aortic aneurysm with rupture" }, { "code": "EK91", "title": "Dermatoses which may presage cutaneous lymphoma" }, { "code": "MH12.1", "title": "Death occurring less than 24 hours from onset of symptoms, not otherwise explained" }, { "code": "8A44.3", "title": "Certain specified leukodystrophies" }, { "code": "4A00.2", "title": "Genetic susceptibility to particular pathogens" } ]	=== ICD-11 CODES FOUND === [8A80.Z] Migraine, unspecified Also known as: Migraine, unspecified \| Migraine [QA76] Medication or substance that is known to be an allergen without injury or harm Definition: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm. Also known as: Medication or substance that is known to be an allergen without injury or harm Excludes: Medication or substance that is known to be an allergen, as mode of injury or harm [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm Also known as: Medication or substance that is known to be an allergen, as mode of injury or harm \| medication error relating to known allergy to drug or substance \| adverse drug event relating to known allergy to drug or substance [9C40.A0] Papilloedema Definition: Optic disc swelling that results from increased intracranial pressure Also known as: Papilloedema \| Optic disc swelling that results from increased intracranial pressure Includes: Optic disc swelling that results from increased intracranial pressure [PA6Z] Unintentional fall from unspecified height Also known as: Unintentional fall from unspecified height \| fall NOS \| accidental fall \| fall causing injury that resulted in death \| fell NOS [BD50.41] Abdominal aortic aneurysm with rupture Also known as: Abdominal aortic aneurysm with rupture \| abdominal aorta aneurysm rupture \| abdominal aorta aneurysm ruptured \| abdominal aortic aneurysm which has ruptured \| ruptured AAA [EK91] Dermatoses which may presage cutaneous lymphoma Definition: Dermatoses which may represent the earliest stages of cutaneous lymphoma but where it is not possible to confirm their neoplastic nature. Also known as: Dermatoses which may presage cutaneous lymphoma [MH12.1] Death occurring less than 24 hours from onset of symptoms, not otherwise explained Also known as: Death occurring less than 24 hours from onset of symptoms, not otherwise explained \| died without sign of disease \| Death known not to be violent or instantaneous for which no cause can be discovered \| death known not to be violent or instantaneous, cause unknown \| Death without sign of disease Includes: Death known not to be violent or instantaneous for which no cause can be discovered \| Death without sign of disease [8A44.3] Certain specified leukodystrophies Also known as: Certain specified leukodystrophies \| CACH syndrome \| Vanishing white matter disease \| Childhood ataxia with central nervous system hypomyelination \| Congenital or early infantile CACH syndrome [4A00.2] Genetic susceptibility to particular pathogens Also known as: Genetic susceptibility to particular pathogens \| Idiopathic CD4 lymphocytopenia \| Immunodeficiency due to interleukin-1 receptor-associated kinase-4 deficiency \| IRAK4 - [interleukin-1 receptor-associated kinase-4 deficiency] \| Lung fibrosis - immunodeficiency - gonadal dysgenesis === GRAPH WALKS === --- Walk 1 --- [8A80.Z] Migraine, unspecified --PARENT--> [8A80] Migraine Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a... --CHILD--> [8A80.0] Migraine without aura Def: Recurrent headache disorder manifesting in attacks lasting 4-72 hours. The duration of attacks may be shorter in children. Typical characteristics of the headache are unilateral location, pulsating qu... --- Walk 2 --- [8A80.Z] Migraine, unspecified --PARENT--> [8A80] Migraine Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a... --EXCLUDES--> [?] Headache, not elsewhere classified Def: Headache with characteristic features suggesting that it is a unique diagnostic entity, a finding or complaint, but not fulfilling criteria for any of the headache disorders described above.... --- Walk 3 --- [QA76] Medication or substance that is known to be an allergen without injury or harm Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm.... --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --- Walk 4 --- [QA76] Medication or substance that is known to be an allergen without injury or harm Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm.... --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --- Walk 5 --- [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm Def: Incorrect dose - too high... --- Walk 6 --- [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --CHILD--> [PL13.1] Underdosing, as mode of injury or harm	[ "[8A80.Z] Migraine, unspecified\n --PARENT--> [8A80] Migraine\n Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a...\n --CHILD--> [8A80.0] Migraine without aura\n Def: Recurrent headache disorder manifesting in attacks lasting 4-72 hours. The duration of attacks may be shorter in children. Typical characteristics of the headache are unilateral location, pulsating qu...", "[8A80.Z] Migraine, unspecified\n --PARENT--> [8A80] Migraine\n Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a...\n --EXCLUDES--> [?] Headache, not elsewhere classified\n Def: Headache with characteristic features suggesting that it is a unique diagnostic entity, a finding or complaint, but not fulfilling criteria for any of the headache disorders described above....", "[QA76] Medication or substance that is known to be an allergen without injury or harm\n Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm....\n --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance", "[QA76] Medication or substance that is known to be an allergen without injury or harm\n Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm....\n --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance", "[PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance\n --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm\n Def: Incorrect dose - too high...", "[PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance\n --CHILD--> [PL13.1] Underdosing, as mode of injury or harm" ]	8A80.Z	Migraine, unspecified	[ { "from_icd11": "8A80.Z", "icd10_code": "G43B0", "icd10_title": "Ophthalmoplegic migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43409", "icd10_title": "Hemiplegic migraine, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A0", "icd10_title": "Cyclical vomiting, in migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D0", "icd10_title": "Abdominal migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43709", "icd10_title": "Chronic migraine without aura, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A1", "icd10_title": "Cyclical vomiting, in migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43509", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43719", "icd10_title": "Chronic migraine without aura, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43501", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C0", "icd10_title": "Periodic headache syndromes in child or adult, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43401", "icd10_title": "Hemiplegic migraine, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43419", "icd10_title": "Hemiplegic migraine, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43B1", "icd10_title": "Ophthalmoplegic migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C1", "icd10_title": "Periodic headache syndromes in child or adult, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D1", "icd10_title": "Abdominal migraine, intractable" } ]	G43B0	Ophthalmoplegic migraine, not intractable
A 44-year-old female patient, without a personal or family history of psychiatric illness, was admitted to a psychiatric ward for a psychotic episode which has started three days before, characterized by perplexity, self-referent and mystical delusions, irritability, disorganized behavior, and aggressiveness, that had emerged shortly after a cluster of nocturnal GTC seizures. Neither Schneider's first - rank symptoms nor negative symptoms of schizophrenia were present. Additionally, some degree of mental confusion with temporal disorientation, as well as sustained, divided attention and memory deficits were noticed during psychiatric hospitalization. Past medical history was relevant for epilepsy since her early thirties, which had developed after a moderate-to-severe traumatic brain injury (TBI). She did not regularly attend follow-up neurology appointments and had poor adherence to antiepileptic treatment. Ancillary tests undergone during a previous hospitalization in a neurology ward (seven years before the hospitalization in psychiatry) had documented a focal slowing activity in the left frontotemporal topography on electroencephalogram (EEG) and a right cortico-subcortical parietooccipital lesion of encephalomalacia on magnetic resonance imaging (MRI). Additionally, she presented an amnestic mild cognitive impairment, possibly secondary to both the poorly controlled epilepsy and the prior TBI.	4.019531	0.97998	sec[1]/p[0]	en	0.999995	PMC10036178	https://doi.org/10.1155/2023/7960227	[ "psychiatric", "hospitalization", "ward", "which", "additionally", "epilepsy", "neurology", "without", "personal", "family" ]	[ { "code": "6E8Z", "title": "Mental, behavioural or neurodevelopmental disorders, unspecified" }, { "code": "QA00.3", "title": "General mental examination" }, { "code": "QC65", "title": "Family history of mental or behavioural disorder" }, { "code": "QA04.6", "title": "General mental examination, requested by authority" }, { "code": "FB83.1Y", "title": "Other specified osteoporosis" }, { "code": "9C83.12", "title": "Downward gaze deviation" }, { "code": "GA18.Y", "title": "Other specified acquired abnormalities of ovary" }, { "code": "9A20.1", "title": "Non-axial displacement of eyeball" }, { "code": "LA8Y", "title": "Other specified structural developmental anomaly of heart or great vessels" }, { "code": "NC13.0", "title": "Dislocation of shoulder joint" } ]	=== ICD-11 CODES FOUND === [6E8Z] Mental, behavioural or neurodevelopmental disorders, unspecified Also known as: Mental, behavioural or neurodevelopmental disorders, unspecified \| Psychiatric disorder \| mental disease NOS \| mental disorder NOS \| mental illness [QA00.3] General mental examination Also known as: General mental examination \| mental health evaluation \| general psychiatric examination Excludes: examination requested for medicolegal reasons [QC65] Family history of mental or behavioural disorder Also known as: Family history of mental or behavioural disorder \| family history of psychiatric disorder \| Family history of intellectual development disorder \| Family history of mental retardation \| Family history of conditions classifiable as intellectual development disorder [QA04.6] General mental examination, requested by authority Also known as: General mental examination, requested by authority \| evaluation of mental health requested by authority \| psychiatric examination requested by authority \| general psychiatric examination, requested by authority [FB83.1Y] Other specified osteoporosis Also known as: Other specified osteoporosis \| Osteoporosis due to eating disorders \| Osteoporosis due to anorexia \| Osteoporosis due to bulimia \| Osteoporosis due to pregnancy or lactation [9C83.12] Downward gaze deviation Also known as: Downward gaze deviation \| Sustained downward gaze deviation \| Sustained tonic downward gaze deviation \| Setting sun sign \| Intermittent downward gaze deviation [GA18.Y] Other specified acquired abnormalities of ovary Also known as: Other specified acquired abnormalities of ovary \| Prolapse or hernia of ovary or fallopian tube \| displacement of ovary into hernial sac \| displacement of oviduct \| downward displacement of fallopian tube [9A20.1] Non-axial displacement of eyeball Also known as: Non-axial displacement of eyeball \| Downward displacement of eyeball \| Hypoglobus \| Upward displacement of eyeball \| Hyperglobus [LA8Y] Other specified structural developmental anomaly of heart or great vessels Also known as: Other specified structural developmental anomaly of heart or great vessels \| Congenital anomaly of position or spatial relationships of thoraco-abdominal organs \| Usual atrial arrangement \| atrial situs solitus \| Abnormal atrial arrangement [NC13.0] Dislocation of shoulder joint Definition: Displacement of the humerus from the scapula. Also known as: Dislocation of shoulder joint \| dislocation of glenohumeral joint \| dislocation of shoulder \| dislocation of shoulder region \| glenohumeral dislocation === GRAPH WALKS === --- Walk 1 --- [6E8Z] Mental, behavioural or neurodevelopmental disorders, unspecified --PARENT--> [06] Mental, behavioural or neurodevelopmental disorders Def: Mental, behavioural and neurodevelopmental disorders are syndromes characterised by clinically significant disturbance in an individual's cognition, emotional regulation, or behaviour that reflects a ... --RELATED_TO--> [?] Gender incongruence Def: Gender incongruence is characterised by a marked and persistent incongruence between an individual’s experienced gender and the assigned sex. Gender variant behaviour and preferences alone are not a b... --- Walk 2 --- [6E8Z] Mental, behavioural or neurodevelopmental disorders, unspecified --PARENT--> [06] Mental, behavioural or neurodevelopmental disorders Def: Mental, behavioural and neurodevelopmental disorders are syndromes characterised by clinically significant disturbance in an individual's cognition, emotional regulation, or behaviour that reflects a ... --RELATED_TO--> [?] Sleep-wake disorders Def: Sleep-wake disorders are characterised by difficulty initiating or maintaining sleep (insomnia disorders), excessive sleepiness (hypersomnolence disorders), respiratory disturbance during sleep (sleep... --- Walk 3 --- [QA00.3] General mental examination --PARENT--> [QA00] General examination or investigation of persons without complaint or reported diagnosis --EXCLUDES--> [?] Special screening examination for neoplasms --- Walk 4 --- [QA00.3] General mental examination --EXCLUDES--> [?] Examination or observation for reasons other than suspected diseases or conditions or administrative purposes --CHILD--> [?] Examination or observation following transport accident --- Walk 5 --- [QC65] Family history of mental or behavioural disorder --PARENT--> [?] Family history of health problems --CHILD--> [QC61] Family history of malignant neoplasm --- Walk 6 --- [QC65] Family history of mental or behavioural disorder --PARENT--> [?] Family history of health problems --PARENT--> [?] Personal or family history or late effect of prior health problems	[ "[6E8Z] Mental, behavioural or neurodevelopmental disorders, unspecified\n --PARENT--> [06] Mental, behavioural or neurodevelopmental disorders\n Def: Mental, behavioural and neurodevelopmental disorders are syndromes characterised by clinically significant disturbance in an individual's cognition, emotional regulation, or behaviour that reflects a ...\n --RELATED_TO--> [?] Gender incongruence\n Def: Gender incongruence is characterised by a marked and persistent incongruence between an individual’s experienced gender and the assigned sex. Gender variant behaviour and preferences alone are not a b...", "[6E8Z] Mental, behavioural or neurodevelopmental disorders, unspecified\n --PARENT--> [06] Mental, behavioural or neurodevelopmental disorders\n Def: Mental, behavioural and neurodevelopmental disorders are syndromes characterised by clinically significant disturbance in an individual's cognition, emotional regulation, or behaviour that reflects a ...\n --RELATED_TO--> [?] Sleep-wake disorders\n Def: Sleep-wake disorders are characterised by difficulty initiating or maintaining sleep (insomnia disorders), excessive sleepiness (hypersomnolence disorders), respiratory disturbance during sleep (sleep...", "[QA00.3] General mental examination\n --PARENT--> [QA00] General examination or investigation of persons without complaint or reported diagnosis\n --EXCLUDES--> [?] Special screening examination for neoplasms", "[QA00.3] General mental examination\n --EXCLUDES--> [?] Examination or observation for reasons other than suspected diseases or conditions or administrative purposes\n --CHILD--> [?] Examination or observation following transport accident", "[QC65] Family history of mental or behavioural disorder\n --PARENT--> [?] Family history of health problems\n --CHILD--> [QC61] Family history of malignant neoplasm", "[QC65] Family history of mental or behavioural disorder\n --PARENT--> [?] Family history of health problems\n --PARENT--> [?] Personal or family history or late effect of prior health problems" ]	6E8Z	Mental, behavioural or neurodevelopmental disorders, unspecified	[ { "from_icd11": "6E8Z", "icd10_code": "F99", "icd10_title": "Mental disorder, not otherwise specified" }, { "from_icd11": "6E8Z", "icd10_code": "F488", "icd10_title": "Other specified nonpsychotic mental disorders" }, { "from_icd11": "6E8Z", "icd10_code": "F988", "icd10_title": "Other specified behavioral and emotional disorders with onset usually occurring in childhood and adolescence" }, { "from_icd11": "6E8Z", "icd10_code": "F530", "icd10_title": "Postpartum depression" }, { "from_icd11": "6E8Z", "icd10_code": "F688", "icd10_title": "Other specified disorders of adult personality and behavior" }, { "from_icd11": "6E8Z", "icd10_code": "F59", "icd10_title": "Unspecified behavioral syndromes associated with physiological disturbances and physical factors" }, { "from_icd11": "6E8Z", "icd10_code": "V", "icd10_title": "" }, { "from_icd11": "6E8Z", "icd10_code": "F531", "icd10_title": "Puerperal psychosis" }, { "from_icd11": "6E8Z", "icd10_code": "F538", "icd10_title": "" }, { "from_icd11": "6E8Z", "icd10_code": "F539", "icd10_title": "" }, { "from_icd11": "6E8Z", "icd10_code": "F680", "icd10_title": "" }, { "from_icd11": "6E8Z", "icd10_code": "F989", "icd10_title": "Unspecified behavioral and emotional disorders with onset usually occurring in childhood and adolescence" }, { "from_icd11": "6E8Z", "icd10_code": "F99-F99", "icd10_title": "" }, { "from_icd11": "6E8Z", "icd10_code": "F00-F09", "icd10_title": "" }, { "from_icd11": "6E8Z", "icd10_code": "F40-F48", "icd10_title": "" } ]	F99	Mental disorder, not otherwise specified
This case series reports five convalescent plasma donors who had met the convalescent plasma donor requirements: 18-60 years of age, had been declared cured of COVID-19 and had been symptom-free for at least 14 days, do not have infectious diseases through blood transfusions (Hepatitis B, Hepatitis C, syphilis, and HIV), do not have serious comorbid diseases (uncontrolled hypertension and diabetes mellitus, kidney failure, cancer, or heart failure), anti-SARS-CoV-2 IgG titer showed (at least) ≥ 1: 320, and RT-PCR results from naso-oropharyngeal swabs prior to plasmapheresis were negative. These requirements were taken from protocol study of Efficacy and safety of convalescent plasma transfusion administered as adjunctive treatment to standard treatment in moderate, severe, and/or critically ill patients with COVID-19 by Ministry of Research and Technology/National Research and Innovation Agency. The examination of anti-SARS-CoV-2 IgG levels was performed using a lateral flow ICT Biosensor from South Korea. Plasmapheresis was performed using the Haemonetics ® machine: MCS ® + Mobile Collection System 09000-220-EW at the Blood Transfusion Unit at dr. Saiful Anwar Hospital, Malang. All screening and plasmapheresis processes were performed at dr. Saiful Anwar Hospital, Malang and all of donors had signed the informed consent in front of the conventional plasma team of dr. Saiful Anwar Hospital, Malang.	4.011719	0.825684	sec[1]/p[0]	en	0.999996	34790190	https://doi.org/10.3389/fimmu.2021.633323	[ "plasma", "convalescent", "plasmapheresis", "saiful", "anwar", "malang", "donors", "requirements", "covid", "least" ]	[ { "code": "2A83.2", "title": "Solitary plasmacytoma" }, { "code": "2A83.Z", "title": "Plasma cell neoplasm, unspecified" }, { "code": "5D0Y", "title": "Other specified metabolic disorders" }, { "code": "2A83.Y", "title": "Other specified plasma cell neoplasms" }, { "code": "2A83.4", "title": "Plasma cell leukaemia" }, { "code": "QB7Z", "title": "Convalescence, unspecified" }, { "code": "QB7Y", "title": "Other specified convalescence" }, { "code": "QB73", "title": "Convalescence following combined treatment" }, { "code": "QB72", "title": "Convalescence following treatment of fracture" }, { "code": "QB71", "title": "Convalescence following psychotherapy" } ]	=== ICD-11 CODES FOUND === [2A83.2] Solitary plasmacytoma Definition: A single focus of clonal (malignant) plasma cells either in the bone or in another anatomic site without peripheral blood involvement. Also known as: Solitary plasmacytoma \| solitary plasmacytoma without mention of remission \| solitary myeloma \| localised malignant plasma cell tumour NOS \| plasmacytoma NOS Includes: solitary myeloma [2A83.Z] Plasma cell neoplasm, unspecified Also known as: Plasma cell neoplasm, unspecified \| Plasma cell neoplasms \| plasma cell tumours \| plasma cells dyscrasia \| plasma cell neoplasm NOS [5D0Y] Other specified metabolic disorders Also known as: Other specified metabolic disorders \| Disorders of plasma-protein metabolism, not elsewhere classified \| abnormal protein transport \| dysproteinaemia \| Absence of albumin in blood [2A83.Y] Other specified plasma cell neoplasms Also known as: Other specified plasma cell neoplasms \| POEMS syndrome \| Osteosclerotic myeloma \| Peripheral neuropathy - organomegaly - endocrinopathy - monoclonal plasma cell disorder - skin changes [2A83.4] Plasma cell leukaemia Definition: An aggressive plasma cell neoplasm. It is characterised by the presence of neoplastic plasma cells in the peripheral blood (PB). The neoplastic plasma cells comprise more than 20% of the white cells in the PB or the number of clonal plasma cells in the PB exceeds 2x10⁹/L. Also known as: Plasma cell leukaemia \| plasma cell leukaemia, NOS \| leukemic plasma cell \| plasma cell leukaemia without mention of remission \| plasmacytic leukaemia [QB7Z] Convalescence, unspecified Also known as: Convalescence, unspecified \| convalescent [QB7Y] Other specified convalescence Also known as: Other specified convalescence \| Convalescence following surgery \| Convalescence following surgery treatment for fracture \| Convalescence following radiotherapy [QB73] Convalescence following combined treatment Definition: Convalescence following any combination of rehabilitation treatments including cardiac rehabilitation, alcohol rehabilitation, drug rehabilitation, psychotherapy, and physical therapy Also known as: Convalescence following combined treatment [QB72] Convalescence following treatment of fracture Also known as: Convalescence following treatment of fracture [QB71] Convalescence following psychotherapy Also known as: Convalescence following psychotherapy === GRAPH WALKS === --- Walk 1 --- [2A83.2] Solitary plasmacytoma Def: A single focus of clonal (malignant) plasma cells either in the bone or in another anatomic site without peripheral blood involvement.... --PARENT--> [2A83] Plasma cell neoplasms Def: Plasma cell neoplasms are a group of disorders characterized by the monoclonal expansion of terminally differentiated B cells (plasma cells) that produce monoclonal immunoglobulins, known as M protein... --CHILD--> [2A83.0] Monoclonal gammopathy of undetermined significance --- Walk 2 --- [2A83.2] Solitary plasmacytoma Def: A single focus of clonal (malignant) plasma cells either in the bone or in another anatomic site without peripheral blood involvement.... --PARENT--> [2A83] Plasma cell neoplasms Def: Plasma cell neoplasms are a group of disorders characterized by the monoclonal expansion of terminally differentiated B cells (plasma cells) that produce monoclonal immunoglobulins, known as M protein... --CHILD--> [2A83.1] Plasma cell myeloma Def: A bone marrow-based plasma cell neoplasm usually characterised by presence of a serum monoclonal protein and/or urinary light chains. ”CRAB” criteria (calcium elevation (hypercalcaemia), renal failure... --- Walk 3 --- [2A83.Z] Plasma cell neoplasm, unspecified --PARENT--> [2A83] Plasma cell neoplasms Def: Plasma cell neoplasms are a group of disorders characterized by the monoclonal expansion of terminally differentiated B cells (plasma cells) that produce monoclonal immunoglobulins, known as M protein... --CHILD--> [2A83.2] Solitary plasmacytoma Def: A single focus of clonal (malignant) plasma cells either in the bone or in another anatomic site without peripheral blood involvement.... --- Walk 4 --- [2A83.Z] Plasma cell neoplasm, unspecified --PARENT--> [2A83] Plasma cell neoplasms Def: Plasma cell neoplasms are a group of disorders characterized by the monoclonal expansion of terminally differentiated B cells (plasma cells) that produce monoclonal immunoglobulins, known as M protein... --CHILD--> [2A83.0] Monoclonal gammopathy of undetermined significance --- Walk 5 --- [5D0Y] Other specified metabolic disorders --PARENT--> [?] Other metabolic disorders --CHILD--> [5D0Y] Other specified metabolic disorders --- Walk 6 --- [5D0Y] Other specified metabolic disorders --PARENT--> [?] Other metabolic disorders --CHILD--> [5D0Y] Other specified metabolic disorders	[ "[2A83.2] Solitary plasmacytoma\n Def: A single focus of clonal (malignant) plasma cells either in the bone or in another anatomic site without peripheral blood involvement....\n --PARENT--> [2A83] Plasma cell neoplasms\n Def: Plasma cell neoplasms are a group of disorders characterized by the monoclonal expansion of terminally differentiated B cells (plasma cells) that produce monoclonal immunoglobulins, known as M protein...\n --CHILD--> [2A83.0] Monoclonal gammopathy of undetermined significance", "[2A83.2] Solitary plasmacytoma\n Def: A single focus of clonal (malignant) plasma cells either in the bone or in another anatomic site without peripheral blood involvement....\n --PARENT--> [2A83] Plasma cell neoplasms\n Def: Plasma cell neoplasms are a group of disorders characterized by the monoclonal expansion of terminally differentiated B cells (plasma cells) that produce monoclonal immunoglobulins, known as M protein...\n --CHILD--> [2A83.1] Plasma cell myeloma\n Def: A bone marrow-based plasma cell neoplasm usually characterised by presence of a serum monoclonal protein and/or urinary light chains. ”CRAB” criteria (calcium elevation (hypercalcaemia), renal failure...", "[2A83.Z] Plasma cell neoplasm, unspecified\n --PARENT--> [2A83] Plasma cell neoplasms\n Def: Plasma cell neoplasms are a group of disorders characterized by the monoclonal expansion of terminally differentiated B cells (plasma cells) that produce monoclonal immunoglobulins, known as M protein...\n --CHILD--> [2A83.2] Solitary plasmacytoma\n Def: A single focus of clonal (malignant) plasma cells either in the bone or in another anatomic site without peripheral blood involvement....", "[2A83.Z] Plasma cell neoplasm, unspecified\n --PARENT--> [2A83] Plasma cell neoplasms\n Def: Plasma cell neoplasms are a group of disorders characterized by the monoclonal expansion of terminally differentiated B cells (plasma cells) that produce monoclonal immunoglobulins, known as M protein...\n --CHILD--> [2A83.0] Monoclonal gammopathy of undetermined significance", "[5D0Y] Other specified metabolic disorders\n --PARENT--> [?] Other metabolic disorders\n --CHILD--> [5D0Y] Other specified metabolic disorders", "[5D0Y] Other specified metabolic disorders\n --PARENT--> [?] Other metabolic disorders\n --CHILD--> [5D0Y] Other specified metabolic disorders" ]	2A83.2	Solitary plasmacytoma	[ { "from_icd11": "2A83.2", "icd10_code": "C9030", "icd10_title": "Solitary plasmacytoma not having achieved remission" }, { "from_icd11": "2A83.2", "icd10_code": "C9032", "icd10_title": "Solitary plasmacytoma in relapse" }, { "from_icd11": "2A83.2", "icd10_code": "C9031", "icd10_title": "Solitary plasmacytoma in remission" }, { "from_icd11": "2A83.2", "icd10_code": "C903", "icd10_title": "Solitary plasmacytoma" }, { "from_icd11": "2A83.Z", "icd10_code": "C90", "icd10_title": "Multiple myeloma and malignant plasma cell neoplasms" }, { "from_icd11": "2A83.4", "icd10_code": "C9010", "icd10_title": "Plasma cell leukemia not having achieved remission" }, { "from_icd11": "2A83.4", "icd10_code": "C9012", "icd10_title": "Plasma cell leukemia in relapse" }, { "from_icd11": "2A83.4", "icd10_code": "C9011", "icd10_title": "Plasma cell leukemia in remission" }, { "from_icd11": "2A83.4", "icd10_code": "C901", "icd10_title": "Plasma cell leukemia" }, { "from_icd11": "QB7Z", "icd10_code": "Z54", "icd10_title": "" }, { "from_icd11": "QB7Z", "icd10_code": "Z540", "icd10_title": "" }, { "from_icd11": "QB7Z", "icd10_code": "Z541", "icd10_title": "" }, { "from_icd11": "QB7Z", "icd10_code": "Z548", "icd10_title": "" }, { "from_icd11": "QB7Z", "icd10_code": "Z549", "icd10_title": "" }, { "from_icd11": "QB73", "icd10_code": "Z547", "icd10_title": "" } ]	C9030	Solitary plasmacytoma not having achieved remission
Case 1: A 75-year-old man was referred for the endoscopic diagnosis and treatment of a rectal subepithelial tumor. Endoscopic ultrasonography-assisted fine-needle aspiration revealed a gastrointestinal stromal tumor (GIST). Case 2: A 77-year-old woman with an 8-mm rectal neuroendocrine tumor (NET) was referred to our department . EFTR was chosen since endoscopic ultrasonography indicated a suspected continuity between the tumor and the muscularis propria. Removal of lesions from both patients was performed en bloc in a full-thickness fashion . Subsequently, endoscopic hand suturing was performed using V-loc absorbable barbed sutures (Covidien, Mansfield, Massachusetts, USA) and a flexible needle holder (SutuArt; Olympus, Tokyo, Japan). In Case 1, a mucosal clipping was performed after a muscular-layer suturing by endoscopic hand suturing. In Case 2, a complete muscular-layer suturing was followed by a mucosal suturing in a turned-back fashion due to sufficient residual suture . The procedures required 75 min for excision and 60 min for closure in Case 1; and 19 min for excision and 39 min for closure in Case 2, respectively. Both patients were able to resume their diet on postoperative day 1 and were discharged on postoperative day 3. No postoperative adverse events were observed in either patient. Pathological examination confirmed the complete resection of the low-risk GIST and NET, respectively.	3.875	0.977539	sec[0]/p[1]	en	0.999996	PMC11473185	https://doi.org/10.1055/a-2420-7896	[ "endoscopic", "suturing", "tumor", "postoperative", "referred", "rectal", "ultrasonography", "needle", "gist", "both" ]	[ { "code": "DA25.3Y/PK80.32", "title": "Oesophageal ulcer due to endoscopic procedures" }, { "code": "DA42.8Z/PK80.32", "title": "Gastritis due to endoscopic procedures" }, { "code": "DA51.5Y/PK80.32", "title": "Duodenitis due to endoscopic procedures" }, { "code": "PL11.4", "title": "Failure of sterile precautions, as mode of injury or harm" }, { "code": "PK80.92", "title": "Vascular procedure associated with injury or harm, endoscopic approach" }, { "code": "QB85", "title": "Attention to surgical dressings, drains or sutures" }, { "code": "EH93.1", "title": "Foreign body reaction to inorganic matter in the skin" }, { "code": "JA84.3", "title": "Maternal care for cervical incompetence" }, { "code": "PK9C.31", "title": "Mechanical complication of permanent sutures" }, { "code": "LB70.0Z", "title": "Craniosynostosis, unspecified" } ]	=== ICD-11 CODES FOUND === [PL11.4] Failure of sterile precautions, as mode of injury or harm Definition: An infection occurred because standard procedures designed to minimize the risk of hospital acquired infection were not followed or were insufficient. Also known as: Failure of sterile precautions, as mode of injury or harm \| failure of sterile precautions during intervention \| contamination as mode of injury or harm \| failure to take proper precautions \| Failure of sterile precautions during surgical and medical care Excludes: Failure of sterile precautions without injury or harm [PK80.92] Vascular procedure associated with injury or harm, endoscopic approach Also known as: Vascular procedure associated with injury or harm, endoscopic approach Excludes: Circumstances associated with a surgical or other medical procedure influencing the episode of care, without injury or harm [QB85] Attention to surgical dressings, drains or sutures Also known as: Attention to surgical dressings, drains or sutures \| Change of dressing \| Change of suture \| Removal of drain \| Removal of dressing [EH93.1] Foreign body reaction to inorganic matter in the skin Definition: A usually granulomatous, often sarcoidal reaction to the presence in the skin of inorganic foreign material which cannot be degraded or eliminated. Responsible agents include tattoo pigment, suture materials, silica, zirconium, aluminium, paraffin, and silicone. Also known as: Foreign body reaction to inorganic matter in the skin \| Silica granuloma \| Foreign body granuloma due to silica \| Talc granuloma \| Cutaneous suture granuloma [JA84.3] Maternal care for cervical incompetence Also known as: Maternal care for cervical incompetence \| maternal care for cervical incompetence, unspecified trimester \| maternal care for cervical insufficiency \| cervical incompetence in pregnancy \| Maternal care for cerclage with or without mention of cervical incompetence [PK9C.31] Mechanical complication of permanent sutures Also known as: Mechanical complication of permanent sutures [LB70.0Z] Craniosynostosis, unspecified Also known as: Craniosynostosis, unspecified \| Craniosynostosis \| congenital ossification of cranial sutures \| congenital ossification of sutures of skull \| craniostenosis === GRAPH WALKS === --- Walk 1 --- [PL11.4] Failure of sterile precautions, as mode of injury or harm Def: An infection occurred because standard procedures designed to minimize the risk of hospital acquired infection were not followed or were insufficient.... --PARENT--> [PL11] Mode of injury or harm associated with a surgical or other medical procedure --CHILD--> [PL11.0] Cut, puncture or tear, as mode of injury or harm Def: The cut or puncture occurs when a solid organ or blood vessel or nerve is unintentionally lacerated or otherwise damaged during a surgical or medical procedure. The cut or puncture must not be require... --- Walk 2 --- [PL11.4] Failure of sterile precautions, as mode of injury or harm Def: An infection occurred because standard procedures designed to minimize the risk of hospital acquired infection were not followed or were insufficient.... --PARENT--> [PL11] Mode of injury or harm associated with a surgical or other medical procedure --CHILD--> [PL11.0] Cut, puncture or tear, as mode of injury or harm Def: The cut or puncture occurs when a solid organ or blood vessel or nerve is unintentionally lacerated or otherwise damaged during a surgical or medical procedure. The cut or puncture must not be require... --- Walk 3 --- [PK80.92] Vascular procedure associated with injury or harm, endoscopic approach --EXCLUDES--> [?] Circumstances associated with a surgical or other medical procedure influencing the episode of care, without injury or harm --CHILD--> [?] Foreign body accidentally left in body without injury or harm Def: A foreign body is any solid material not normally found in the human body. It is accidentally left in the body if there was no specific intention to keep it in the body.... --- Walk 4 --- [PK80.92] Vascular procedure associated with injury or harm, endoscopic approach --PARENT--> [PK80.9] Vascular procedure associated with injury or harm in therapeutic use --CHILD--> [PK80.91] Vascular procedure associated with injury or harm, percutaneous approach	[ "[PL11.4] Failure of sterile precautions, as mode of injury or harm\n Def: An infection occurred because standard procedures designed to minimize the risk of hospital acquired infection were not followed or were insufficient....\n --PARENT--> [PL11] Mode of injury or harm associated with a surgical or other medical procedure\n --CHILD--> [PL11.0] Cut, puncture or tear, as mode of injury or harm\n Def: The cut or puncture occurs when a solid organ or blood vessel or nerve is unintentionally lacerated or otherwise damaged during a surgical or medical procedure. The cut or puncture must not be require...", "[PL11.4] Failure of sterile precautions, as mode of injury or harm\n Def: An infection occurred because standard procedures designed to minimize the risk of hospital acquired infection were not followed or were insufficient....\n --PARENT--> [PL11] Mode of injury or harm associated with a surgical or other medical procedure\n --CHILD--> [PL11.0] Cut, puncture or tear, as mode of injury or harm\n Def: The cut or puncture occurs when a solid organ or blood vessel or nerve is unintentionally lacerated or otherwise damaged during a surgical or medical procedure. The cut or puncture must not be require...", "[PK80.92] Vascular procedure associated with injury or harm, endoscopic approach\n --EXCLUDES--> [?] Circumstances associated with a surgical or other medical procedure influencing the episode of care, without injury or harm\n --CHILD--> [?] Foreign body accidentally left in body without injury or harm\n Def: A foreign body is any solid material not normally found in the human body. It is accidentally left in the body if there was no specific intention to keep it in the body....", "[PK80.92] Vascular procedure associated with injury or harm, endoscopic approach\n --PARENT--> [PK80.9] Vascular procedure associated with injury or harm in therapeutic use\n --CHILD--> [PK80.91] Vascular procedure associated with injury or harm, percutaneous approach" ]	DA25.3Y/PK80.32	Oesophageal ulcer due to endoscopic procedures	[ { "from_icd11": "PL11.4", "icd10_code": "Y62", "icd10_title": "Failure of sterile precautions during surgical and medical care" }, { "from_icd11": "PL11.4", "icd10_code": "Y620", "icd10_title": "Failure of sterile precautions during surgical operation" }, { "from_icd11": "PL11.4", "icd10_code": "Y621", "icd10_title": "Failure of sterile precautions during infusion or transfusion" }, { "from_icd11": "PL11.4", "icd10_code": "Y622", "icd10_title": "Failure of sterile precautions during kidney dialysis and other perfusion" }, { "from_icd11": "PL11.4", "icd10_code": "Y623", "icd10_title": "Failure of sterile precautions during injection or immunization" }, { "from_icd11": "PL11.4", "icd10_code": "Y624", "icd10_title": "Failure of sterile precautions during endoscopic examination" }, { "from_icd11": "PL11.4", "icd10_code": "Y625", "icd10_title": "Failure of sterile precautions during heart catheterization" }, { "from_icd11": "PL11.4", "icd10_code": "Y626", "icd10_title": "Failure of sterile precautions during aspiration, puncture and other catheterization" }, { "from_icd11": "PL11.4", "icd10_code": "Y628", "icd10_title": "Failure of sterile precautions during other surgical and medical care" }, { "from_icd11": "PL11.4", "icd10_code": "Y629", "icd10_title": "Failure of sterile precautions during unspecified surgical and medical care" }, { "from_icd11": "QB85", "icd10_code": "Z481", "icd10_title": "Encounter for planned postprocedural wound closure" }, { "from_icd11": "QB85", "icd10_code": "Z4821", "icd10_title": "Encounter for aftercare following heart transplant" }, { "from_icd11": "QB85", "icd10_code": "Z483", "icd10_title": "Aftercare following surgery for neoplasm" }, { "from_icd11": "QB85", "icd10_code": "Z4823", "icd10_title": "Encounter for aftercare following liver transplant" }, { "from_icd11": "QB85", "icd10_code": "Z4822", "icd10_title": "Encounter for aftercare following kidney transplant" } ]	Y62	Failure of sterile precautions during surgical and medical care
The patient's pertinent serum and CSF laboratory findings are summarized in Table 1 . Initial laboratory values showed normocytic anemia with low hemoglobin, low hematocrit, and normal mean corpuscular volume. The erythrocyte sedimentation rate was elevated, and the activated partial thromboplastin time was normal. The serum rapid plasma reagin (RPR) test was positive which triggered further diagnostic investigation. A lumbar puncture was performed on day three. Findings in the CSF included elevated red blood cells (RBCs), elevated white blood cells (WBCs) with neutrophilic predominance, low glucose (serum glucose was within normal limits), and elevated protein. These findings were consistent with meningoencephalitis. On day four, the cryptococcal antigen latex agglutination test returned negative. On day five, the HIV-1 antibody test returned positive along with an elevated quantitative polymerase chain reaction test. Additionally, there was a significant reduction seen in the patient's CD4 count, indicating immunosuppression due to acquired immunodeficiency syndrome (AIDS). With the combination of meningoencephalitis and aortitis shown on TEE, the patient was started on intravenous penicillin G as per protocol. Serum T. pallidum micro-hemagglutination assay and CSF venereal disease research laboratory (VDRL) tests later returned positive, confirming the diagnosis of meningovascular neurosyphilis.	4.054688	0.966797	sec[1]/p[2]	en	0.999995	PMC10115213	https://doi.org/10.7759/cureus.36405	[ "serum", "laboratory", "returned", "blood", "cells", "glucose", "meningoencephalitis", "pertinent", "summarized", "normocytic" ]	[ { "code": "NE80.3", "title": "Other serum reactions" }, { "code": "5D0Y", "title": "Other specified metabolic disorders" }, { "code": "5B91.0", "title": "Hypercalcaemia" }, { "code": "4A84.Y", "title": "Other specified anaphylaxis" }, { "code": "5C50.F2", "title": "Homocarnosinosis" }, { "code": "QA00.C", "title": "Laboratory examination" }, { "code": "MG71.Z", "title": "Abnormal laboratory results, not elsewhere classified, unspecified" }, { "code": "MG71.Y", "title": "Other specified abnormal laboratory results, not elsewhere classified" }, { "code": "QA0B", "title": "Preprocedural examination" }, { "code": "MA14.0", "title": "Laboratory evidence of human immunodeficiency virus" } ]	=== ICD-11 CODES FOUND === [NE80.3] Other serum reactions Also known as: Other serum reactions \| Allergic reaction to serum \| serum allergy \| Complications of vaccination, protein sickness \| Protein sickness Excludes: serum hepatitis [5D0Y] Other specified metabolic disorders Also known as: Other specified metabolic disorders \| Disorders of plasma-protein metabolism, not elsewhere classified \| abnormal protein transport \| dysproteinaemia \| Absence of albumin in blood [5B91.0] Hypercalcaemia Definition: Hypercalcaemia is a condition caused by increased calcium levels. The higher the calcium levels and the faster its level rises, the more severe will be the symptoms. When present, symptoms are caused by dehydration secondary to urinary losses of calcium, water and other electrolytes, and to an increase in membrane potential caused by the elevation in extracellular fluid ionized calcium concentration. Patients with moderate to severe hypercalcaemia often complain of nausea and vomiting, symptoms Also known as: Hypercalcaemia \| Calcium excess \| elevated serum calcium \| hypercalcaemic crisis \| hypercalcaemic syndrome [4A84.Y] Other specified anaphylaxis Also known as: Other specified anaphylaxis \| Latex-induced anaphylaxis \| Anaphylaxis due to latex \| Latex anaphylaxis \| Anaphylactic shock due to serum [5C50.F2] Homocarnosinosis Definition: Homocarnosinosis is a metabolic defect characterised by progressive spastic diplegia, intellectual deficit and retinitis pigmentosa. This extremely rare disorder has been reported in only one family, namely a woman and three of her children. The latter showed but their mother was symptom free. It is therefore uncertain whether there is a relationship between the biochemical defect and the clinical symptoms. Inheritance in the reported family seems to be autosomal dominant. Also known as: Homocarnosinosis \| Homocarnosinase deficiency \| Serum carnosinase deficiency [QA00.C] Laboratory examination Also known as: Laboratory examination \| laboratory test [MG71.Z] Abnormal laboratory results, not elsewhere classified, unspecified Also known as: Abnormal laboratory results, not elsewhere classified, unspecified \| Abnormal laboratory results, not elsewhere classified [MG71.Y] Other specified abnormal laboratory results, not elsewhere classified Also known as: Other specified abnormal laboratory results, not elsewhere classified [QA0B] Preprocedural examination Definition: Evaluation and testing for assessment and proactive management of risks of perioperative morbidity and mortality and implements measurements to minimize risks. Also known as: Preprocedural examination \| Encounter for preoperative examinations \| Preprocedural general examination \| Encounter for preprocedural examination NOS \| preoperative assessment [MA14.0] Laboratory evidence of human immunodeficiency virus Also known as: Laboratory evidence of human immunodeficiency virus \| human immunodeficiency virus test positive \| positive test for HIV \| laboratory evidence of HIV \| Nonconclusive HIV-test finding in infants Excludes: Human immunodeficiency disease complicating pregnancy, childbirth or the puerperium \| Human immunodeficiency virus disease \| Asymptomatic human immunodeficiency virus infection === GRAPH WALKS === --- Walk 1 --- [NE80.3] Other serum reactions --EXCLUDES--> [?] Acute hepatitis B without Hepatitis D virus co-infection Def: Acute liver injury related with hepatitis B virus (HBV). Acute hepatitis B is suspected based on positive HBsAg and high-titer IgM anti-HBc. However, other causes of acute viral hepatitis may not be f... --CHILD--> [?] Transfusion hepatitis --- Walk 2 --- [NE80.3] Other serum reactions --RELATED_TO--> [?] Anaphylactic shock due to serum --PARENT--> [?] Anaphylaxis Def: Anaphylaxis is a severe, life-threatening systemic hypersensitivity reaction characterised by being rapid in onset with potentially life-threatening airway, breathing, or circulatory problems and is u... --- Walk 3 --- [5D0Y] Other specified metabolic disorders --PARENT--> [?] Other metabolic disorders --CHILD--> [5D01] Tumour lysis syndrome Def: This is a group of metabolic complications that can occur after treatment of cancer, usually lymphomas and leukaemias, and sometimes even without treatment. These complications are caused by the break... --- Walk 4 --- [5D0Y] Other specified metabolic disorders --PARENT--> [?] Other metabolic disorders --RELATED_TO--> [?] Tophaceous gout Def: Tophi are precipitates of monosodium urate in the tissues of patients with hyperuricaemia and may be associated with other manifestations of hyperuricaemia including gouty arthropathy. They present pa... --- Walk 5 --- [5B91.0] Hypercalcaemia Def: Hypercalcaemia is a condition caused by increased calcium levels. The higher the calcium levels and the faster its level rises, the more severe will be the symptoms. When present, symptoms are caused ... --RELATED_TO--> [?] Myopathy due to hypercalcaemia --PARENT--> [?] Neurological disorders due to an excess of micro or macro nutrients --- Walk 6 --- [5B91.0] Hypercalcaemia Def: Hypercalcaemia is a condition caused by increased calcium levels. The higher the calcium levels and the faster its level rises, the more severe will be the symptoms. When present, symptoms are caused ... --RELATED_TO--> [?] Myopathy due to hypercalcaemia --PARENT--> [?] Neurological disorders due to an excess of micro or macro nutrients	[ "[NE80.3] Other serum reactions\n --EXCLUDES--> [?] Acute hepatitis B without Hepatitis D virus co-infection\n Def: Acute liver injury related with hepatitis B virus (HBV). Acute hepatitis B is suspected based on positive HBsAg and high-titer IgM anti-HBc. However, other causes of acute viral hepatitis may not be f...\n --CHILD--> [?] Transfusion hepatitis", "[NE80.3] Other serum reactions\n --RELATED_TO--> [?] Anaphylactic shock due to serum\n --PARENT--> [?] Anaphylaxis\n Def: Anaphylaxis is a severe, life-threatening systemic hypersensitivity reaction characterised by being rapid in onset with potentially life-threatening airway, breathing, or circulatory problems and is u...", "[5D0Y] Other specified metabolic disorders\n --PARENT--> [?] Other metabolic disorders\n --CHILD--> [5D01] Tumour lysis syndrome\n Def: This is a group of metabolic complications that can occur after treatment of cancer, usually lymphomas and leukaemias, and sometimes even without treatment. These complications are caused by the break...", "[5D0Y] Other specified metabolic disorders\n --PARENT--> [?] Other metabolic disorders\n --RELATED_TO--> [?] Tophaceous gout\n Def: Tophi are precipitates of monosodium urate in the tissues of patients with hyperuricaemia and may be associated with other manifestations of hyperuricaemia including gouty arthropathy. They present pa...", "[5B91.0] Hypercalcaemia\n Def: Hypercalcaemia is a condition caused by increased calcium levels. The higher the calcium levels and the faster its level rises, the more severe will be the symptoms. When present, symptoms are caused ...\n --RELATED_TO--> [?] Myopathy due to hypercalcaemia\n --PARENT--> [?] Neurological disorders due to an excess of micro or macro nutrients", "[5B91.0] Hypercalcaemia\n Def: Hypercalcaemia is a condition caused by increased calcium levels. The higher the calcium levels and the faster its level rises, the more severe will be the symptoms. When present, symptoms are caused ...\n --RELATED_TO--> [?] Myopathy due to hypercalcaemia\n --PARENT--> [?] Neurological disorders due to an excess of micro or macro nutrients" ]	NE80.3	Other serum reactions	[ { "from_icd11": "NE80.3", "icd10_code": "T880XXA", "icd10_title": "Infection following immunization, initial encounter" }, { "from_icd11": "NE80.3", "icd10_code": "T8061XA", "icd10_title": "Other serum reaction due to administration of blood and blood products, initial encounter" }, { "from_icd11": "NE80.3", "icd10_code": "T8069XA", "icd10_title": "Other serum reaction due to other serum, initial encounter" }, { "from_icd11": "NE80.3", "icd10_code": "T8062XA", "icd10_title": "Other serum reaction due to vaccination, initial encounter" }, { "from_icd11": "NE80.3", "icd10_code": "T806", "icd10_title": "Other serum reactions" }, { "from_icd11": "NE80.3", "icd10_code": "T880", "icd10_title": "Infection following immunization" }, { "from_icd11": "5C50.F2", "icd10_code": "E7281", "icd10_title": "Disorders of gamma aminobutyric acid metabolism" }, { "from_icd11": "5C50.F2", "icd10_code": "E728", "icd10_title": "Other specified disorders of amino-acid metabolism" }, { "from_icd11": "QA00.C", "icd10_code": "Z017", "icd10_title": "" }, { "from_icd11": "QA0B", "icd10_code": "Z01818", "icd10_title": "Encounter for other preprocedural examination" }, { "from_icd11": "QA0B", "icd10_code": "Z01810", "icd10_title": "Encounter for preprocedural cardiovascular examination" }, { "from_icd11": "QA0B", "icd10_code": "Z01812", "icd10_title": "Encounter for preprocedural laboratory examination" }, { "from_icd11": "MA14.0", "icd10_code": "R75", "icd10_title": "Inconclusive laboratory evidence of human immunodeficiency virus [HIV]" } ]	T880XXA	Infection following immunization, initial encounter
This case was confirmed using detailed clinical and advanced imaging findings. The involvement of the radiology and oncology teams reinforced this case. Additionally, this case examined other published cases and revealed similarities and differences between these cases. Similar to previously studied cases, ours involved an elderly man who had never undergone PSA screening and was confirmed to have prostate cancer metastases. However, the present case is unique because he presented with hip pain as his chief complaint. In addition, the current case is one of the three reports in which an MRI was performed earlier in the evaluation process. Although this difference may be due to the fact that previous examples were reported some years ago when MRI was not widely utilized, the present case also demonstrates the value of early MRI for chiropractors to detect spinal metastases. However, the current case may not be broadly generalizable. As the scope of practice varies among countries, chiropractors might not have the authority to request advanced imaging, such as an MRI. This case might not be presented to the chiropractor if the setting routinely conducts prostate cancer screening for citizens. Furthermore, this case lacked biopsy findings as the examination was not conducted by the same healthcare organization and the report could not be retrieved. And finally, a true case of death was not identified.	3.851563	0.961914	sec[2]/p[6]	en	0.999996	PMC9941037	https://doi.org/10.7759/cureus.34049	[ "this", "cases", "advanced", "imaging", "screening", "prostate", "cancer", "metastases", "however", "present" ]	[ { "code": "4A01.03", "title": "Transient hypogammaglobulinaemia of infancy" }, { "code": "JB20.Z", "title": "Single spontaneous delivery, unspecified" }, { "code": "QA48.0", "title": "Care or examination immediately after delivery" }, { "code": "MG2A", "title": "Ageing associated decline in intrinsic capacity" }, { "code": "9B75.03", "title": "Atrophic late-stage age-related macular degeneration" }, { "code": "6D8Z&XS25", "title": "End stage dementia" }, { "code": "9B75.04", "title": "Neovascular late-stage age-related macular degeneration" }, { "code": "BC63.10", "title": "High-grade second degree atrioventricular block" }, { "code": "5A74.Y", "title": "Other specified adrenocortical insufficiency" }, { "code": "MB27.3", "title": "Disturbance of body image" } ]	=== ICD-11 CODES FOUND === [4A01.03] Transient hypogammaglobulinaemia of infancy Also known as: Transient hypogammaglobulinaemia of infancy \| immunoglobulin maturational delay \| THI - [transient hypogammaglobulinaemia of infancy] [JB20.Z] Single spontaneous delivery, unspecified Also known as: Single spontaneous delivery, unspecified \| Single spontaneous delivery \| spontaneous delivery NOS \| normal delivery NOS \| uncomplicated delivery [QA48.0] Care or examination immediately after delivery Also known as: Care or examination immediately after delivery \| care and observation in uncomplicated delivery cases \| postpartum care immediately after delivery \| postpartum examination immediately after delivery \| Postpartum care after hospital delivery Excludes: Complications predominantly related to the puerperium [MG2A] Ageing associated decline in intrinsic capacity Also known as: Ageing associated decline in intrinsic capacity \| senescence \| senile state \| senile dysfunction \| senility NOS Includes: senescence without mention of psychosis Excludes: Senile dementia [9B75.03] Atrophic late-stage age-related macular degeneration Also known as: Atrophic late-stage age-related macular degeneration \| advanced dry age-related macular degeneration \| advanced dry AMD - [age-related macular degeneration] \| advanced atrophic age related macular degeneration \| Geographic atrophy secondary to age-related macular degeneration without foveal involvement [9B75.04] Neovascular late-stage age-related macular degeneration Also known as: Neovascular late-stage age-related macular degeneration \| advanced exudative age-related macular degeneration \| advanced exudative AMD - [age-related macular degeneration] \| advanced neovascular age related macular degeneration \| neovascular age-related macular degeneration [BC63.10] High-grade second degree atrioventricular block Definition: Form of second degree atrioventricular block in which either multiple consecutive P-waves are not conducted or there are transient periods of atrioventricular dissociation Also known as: High-grade second degree atrioventricular block \| Advanced heart block [5A74.Y] Other specified adrenocortical insufficiency Also known as: Other specified adrenocortical insufficiency \| Congenital adrenocortical insufficiency \| Congenital isolated ACTH deficiency \| Familial adrenal hypoplasia \| Familial hypoadrenocorticism [MB27.3] Disturbance of body image Definition: Excessively negative, distorted, or inaccurate perception of one's own body or parts of it. Also known as: Disturbance of body image === GRAPH WALKS === --- Walk 1 --- [4A01.03] Transient hypogammaglobulinaemia of infancy --PARENT--> [4A01.0] Immunodeficiencies with predominantly antibody defects Def: A disorder characterised by an inability to mount a normal immune response due to antibody (i.e. immunoglobulin) defects... --CHILD--> [4A01.00] Hereditary agammaglobulinaemia with profoundly reduced or absent B cells Def: This refers to a hereditary type of primary immune deficiency disease characterised by a reduction in all types of gamma globulins, and rare X-linked genetic disorder that affects the body's ability t... --- Walk 2 --- [4A01.03] Transient hypogammaglobulinaemia of infancy --PARENT--> [4A01.0] Immunodeficiencies with predominantly antibody defects Def: A disorder characterised by an inability to mount a normal immune response due to antibody (i.e. immunoglobulin) defects... --CHILD--> [4A01.02] Specific antibody deficiency with normal immunoglobulin concentrations or normal number of B cells --- Walk 3 --- [JB20.Z] Single spontaneous delivery, unspecified --PARENT--> [JB20] Single spontaneous delivery Def: A condition caused by the development of a fetus to the culmination of the pregnancy period. This condition is characterised by spontaneous parturition of a neonate from the uterus.... --CHILD--> [JB20.1] Spontaneous breech delivery Def: A condition caused by the development of a fetus to the culmination of the pregnancy period. This condition is characterised by spontaneous parturition of a neonate in breech position from the uterus.... --- Walk 4 --- [JB20.Z] Single spontaneous delivery, unspecified --PARENT--> [JB20] Single spontaneous delivery Def: A condition caused by the development of a fetus to the culmination of the pregnancy period. This condition is characterised by spontaneous parturition of a neonate from the uterus.... --PARENT--> [?] Delivery Def: Birth of one or more neonates from the uterus either spontaneously, assisted, or by caesarean section.... --- Walk 5 --- [QA48.0] Care or examination immediately after delivery --PARENT--> [QA48] Postpartum care or examination --CHILD--> [QA48.2] Routine postpartum follow-up --- Walk 6 --- [QA48.0] Care or examination immediately after delivery --EXCLUDES--> [?] Complications predominantly related to the puerperium Def: A group of conditions characterised as any adverse evolution (complication) which may arise during the approximately six weeks after delivery during which the uterus returns to the original size (puer... --CHILD--> [?] Venous complications in the puerperium	[ "[4A01.03] Transient hypogammaglobulinaemia of infancy\n --PARENT--> [4A01.0] Immunodeficiencies with predominantly antibody defects\n Def: A disorder characterised by an inability to mount a normal immune response due to antibody (i.e. immunoglobulin) defects...\n --CHILD--> [4A01.00] Hereditary agammaglobulinaemia with profoundly reduced or absent B cells\n Def: This refers to a hereditary type of primary immune deficiency disease characterised by a reduction in all types of gamma globulins, and rare X-linked genetic disorder that affects the body's ability t...", "[4A01.03] Transient hypogammaglobulinaemia of infancy\n --PARENT--> [4A01.0] Immunodeficiencies with predominantly antibody defects\n Def: A disorder characterised by an inability to mount a normal immune response due to antibody (i.e. immunoglobulin) defects...\n --CHILD--> [4A01.02] Specific antibody deficiency with normal immunoglobulin concentrations or normal number of B cells", "[JB20.Z] Single spontaneous delivery, unspecified\n --PARENT--> [JB20] Single spontaneous delivery\n Def: A condition caused by the development of a fetus to the culmination of the pregnancy period. This condition is characterised by spontaneous parturition of a neonate from the uterus....\n --CHILD--> [JB20.1] Spontaneous breech delivery\n Def: A condition caused by the development of a fetus to the culmination of the pregnancy period. This condition is characterised by spontaneous parturition of a neonate in breech position from the uterus....", "[JB20.Z] Single spontaneous delivery, unspecified\n --PARENT--> [JB20] Single spontaneous delivery\n Def: A condition caused by the development of a fetus to the culmination of the pregnancy period. This condition is characterised by spontaneous parturition of a neonate from the uterus....\n --PARENT--> [?] Delivery\n Def: Birth of one or more neonates from the uterus either spontaneously, assisted, or by caesarean section....", "[QA48.0] Care or examination immediately after delivery\n --PARENT--> [QA48] Postpartum care or examination\n --CHILD--> [QA48.2] Routine postpartum follow-up", "[QA48.0] Care or examination immediately after delivery\n --EXCLUDES--> [?] Complications predominantly related to the puerperium\n Def: A group of conditions characterised as any adverse evolution (complication) which may arise during the approximately six weeks after delivery during which the uterus returns to the original size (puer...\n --CHILD--> [?] Venous complications in the puerperium" ]	4A01.03	Transient hypogammaglobulinaemia of infancy	[ { "from_icd11": "4A01.03", "icd10_code": "D807", "icd10_title": "Transient hypogammaglobulinemia of infancy" }, { "from_icd11": "JB20.Z", "icd10_code": "O80", "icd10_title": "Encounter for full-term uncomplicated delivery" }, { "from_icd11": "JB20.Z", "icd10_code": "O808", "icd10_title": "" }, { "from_icd11": "JB20.Z", "icd10_code": "O809", "icd10_title": "" }, { "from_icd11": "QA48.0", "icd10_code": "Z390", "icd10_title": "Encounter for care and examination of mother immediately after delivery" }, { "from_icd11": "MG2A", "icd10_code": "R54", "icd10_title": "Age-related physical debility" } ]	D807	Transient hypogammaglobulinemia of infancy
Patient 2 is a now 3-year-old boy who presented for genetic evaluation due to global developmental delay and congenital anomalies. His parents were non-consanguineous and of mixed ethnicity . Both parents are generally healthy and had unremarkable developmental histories. His birth weight 2.81 kg (13th percentile), length 49 cm (32nd percentile) and OFC of 32.1 cm (3rd percentile). Cutis aplasia was found after delivery. He was noted to have a large, irregular skin defect on his posterior scalp with some islands of normal skin. The calvarium in the affected region was thin. Three stellate shaped ulcerations involving vertex and occiput of the scalp were noted (largest measuring approximately 4 cm × 3 cm; the next smallest measuring approximately 3.5 cm × 2.5 cm; and the smallest approximately 1 cm in diameter). The scalp defect was managed conservatively and healed with scarring and patchy alopecia. At 3 years of age he had predominant language delay and lagging behind in his head circumference for age. Examination revealed OFC of 46 cm (<3rd percentile). Scalp was notable for extensive scarring and patchy alopecia. Ears were cupped and mildly simplified. He had broad forehead, hypertelorism with arched eyebrows and a slightly upturned nasal tip. Neurological examination was unremarkable except for expressive language delay. Previous genetic testing included a normal chromosome microarray analysis.	3.853516	0.986328	sec[1]/sec[0]/p[2]	en	0.999995	33167890	https://doi.org/10.1186/s12881-020-01159-y	[ "percentile", "scalp", "delay", "approximately", "genetic", "developmental", "parents", "unremarkable", "skin", "defect" ]	[ { "code": "5B81.00", "title": "Obesity in children or adolescents" }, { "code": "NA01.2&XA6CW5", "title": "Laceration of scalp" }, { "code": "NA00.0Y&XJ1C6", "title": "Haematoma of scalp" }, { "code": "NA00.0Y&XJ8JK", "title": "Nonthermal blister of scalp" }, { "code": "NA00.01", "title": "Contusion of scalp" }, { "code": "EG30.0", "title": "Scalp folliculitis" }, { "code": "MG44.1Z", "title": "Lack of expected normal physiological development, unspecified" }, { "code": "PL14.A", "title": "Delayed diagnosis" }, { "code": "6A00.Z", "title": "Disorders of intellectual development, unspecified" }, { "code": "PL14.B", "title": "Delayed treatment" } ]	=== ICD-11 CODES FOUND === [5B81.00] Obesity in children or adolescents Definition: In infants, children and adolescents, BMI categories for defining obesity vary by age and gender based on WHO growth charts. Children 0 to 5 years have obesity if weight-for-length/height or BMI-for-age is above 3 standard deviations of the median of the WHO Child Growth Standards. Children aged 5 to 19 years have obesity if BMI-for-age is above 2 standard deviations of the median of WHO Growth Reference for School-aged Children and Adolescents. Also known as: Obesity in children or adolescents \| morbid obesity in children or adolescents \| BMI-for age -[body mass index-for-age] percentile greater than 95 percent \| Obesity in infants or children up to 5 years of age \| Obesity in school-aged children or adolescents from 5 to 19 years [NA00.01] Contusion of scalp Also known as: Contusion of scalp \| bruise of scalp \| Contusion of occipital region \| Contusion of parietal region \| Contusion of temporal region [EG30.0] Scalp folliculitis Definition: A non-scarring chronic superficial folliculitis of the scalp that is typically characterised by multiple minute, very itchy pustules within the scalp and which has in the past been termed acne necrotica miliaris. The cause is not well understood but an inflammatory response to Propionibacterium acnes has been postulated. Also known as: Scalp folliculitis \| Acne necrotica miliaris \| Propionibacterium acnes folliculitis of scalp [MG44.1Z] Lack of expected normal physiological development, unspecified Also known as: Lack of expected normal physiological development, unspecified \| Lack of expected normal physiological development \| delayed physiological development \| unspecified delay in development \| development arrest [PL14.A] Delayed diagnosis Also known as: Delayed diagnosis [6A00.Z] Disorders of intellectual development, unspecified Also known as: Disorders of intellectual development, unspecified \| Disorders of intellectual development \| Mental retardation \| Intellectual developmental disorder \| Intellectual disability [PL14.B] Delayed treatment Also known as: Delayed treatment \| avoidable delay in treatment \| Problem associated with delayed administration of a needed medication \| Problem associated with delayed surgery Excludes: Incorrect timing of drug or medicament, as mode of injury \| Non provision of necessary procedure === GRAPH WALKS === --- Walk 1 --- [5B81.00] Obesity in children or adolescents Def: In infants, children and adolescents, BMI categories for defining obesity vary by age and gender based on WHO growth charts. Children 0 to 5 years have obesity if weight-for-length/height or BMI-for-a... --PARENT--> [5B81.0] Obesity due to energy imbalance Def: Obesity is a chronic complex disease defined by excessive adiposity that can impair health. It is in most cases a multifactorial disease due to obesogenic environments, psycho-social factors and genet... --CHILD--> [5B81.00] Obesity in children or adolescents Def: In infants, children and adolescents, BMI categories for defining obesity vary by age and gender based on WHO growth charts. Children 0 to 5 years have obesity if weight-for-length/height or BMI-for-a... --- Walk 2 --- [5B81.00] Obesity in children or adolescents Def: In infants, children and adolescents, BMI categories for defining obesity vary by age and gender based on WHO growth charts. Children 0 to 5 years have obesity if weight-for-length/height or BMI-for-a... --PARENT--> [5B81.0] Obesity due to energy imbalance Def: Obesity is a chronic complex disease defined by excessive adiposity that can impair health. It is in most cases a multifactorial disease due to obesogenic environments, psycho-social factors and genet... --CHILD--> [5B81.00] Obesity in children or adolescents Def: In infants, children and adolescents, BMI categories for defining obesity vary by age and gender based on WHO growth charts. Children 0 to 5 years have obesity if weight-for-length/height or BMI-for-a... --- Walk 3 --- [NA00.01] Contusion of scalp --RELATED_TO--> [?] Bruising of scalp due to birth injury Def: Erythema of the scalp occurring usually as a result of dystocia or application of forceps... --PARENT--> [?] Birth injury to scalp Def: A condition characterised by the presence of damage to the scalp due to physical pressure or injury during delivery.... --- Walk 4 --- [NA00.01] Contusion of scalp --RELATED_TO--> [?] Bruising of scalp due to birth injury Def: Erythema of the scalp occurring usually as a result of dystocia or application of forceps... --PARENT--> [?] Contusion of scalp	[ "[5B81.00] Obesity in children or adolescents\n Def: In infants, children and adolescents, BMI categories for defining obesity vary by age and gender based on WHO growth charts. Children 0 to 5 years have obesity if weight-for-length/height or BMI-for-a...\n --PARENT--> [5B81.0] Obesity due to energy imbalance\n Def: Obesity is a chronic complex disease defined by excessive adiposity that can impair health. It is in most cases a multifactorial disease due to obesogenic environments, psycho-social factors and genet...\n --CHILD--> [5B81.00] Obesity in children or adolescents\n Def: In infants, children and adolescents, BMI categories for defining obesity vary by age and gender based on WHO growth charts. Children 0 to 5 years have obesity if weight-for-length/height or BMI-for-a...", "[5B81.00] Obesity in children or adolescents\n Def: In infants, children and adolescents, BMI categories for defining obesity vary by age and gender based on WHO growth charts. Children 0 to 5 years have obesity if weight-for-length/height or BMI-for-a...\n --PARENT--> [5B81.0] Obesity due to energy imbalance\n Def: Obesity is a chronic complex disease defined by excessive adiposity that can impair health. It is in most cases a multifactorial disease due to obesogenic environments, psycho-social factors and genet...\n --CHILD--> [5B81.00] Obesity in children or adolescents\n Def: In infants, children and adolescents, BMI categories for defining obesity vary by age and gender based on WHO growth charts. Children 0 to 5 years have obesity if weight-for-length/height or BMI-for-a...", "[NA00.01] Contusion of scalp\n --RELATED_TO--> [?] Bruising of scalp due to birth injury\n Def: Erythema of the scalp occurring usually as a result of dystocia or application of forceps...\n --PARENT--> [?] Birth injury to scalp\n Def: A condition characterised by the presence of damage to the scalp due to physical pressure or injury during delivery....", "[NA00.01] Contusion of scalp\n --RELATED_TO--> [?] Bruising of scalp due to birth injury\n Def: Erythema of the scalp occurring usually as a result of dystocia or application of forceps...\n --PARENT--> [?] Contusion of scalp" ]	5B81.00	Obesity in children or adolescents	[ { "from_icd11": "NA01.2&XA6CW5", "icd10_code": "S0101XA", "icd10_title": "Laceration without foreign body of scalp, initial encounter" }, { "from_icd11": "NA01.2&XA6CW5", "icd10_code": "S0101XD", "icd10_title": "Laceration without foreign body of scalp, subsequent encounter" }, { "from_icd11": "NA00.01", "icd10_code": "S0003XA", "icd10_title": "Contusion of scalp, initial encounter" }, { "from_icd11": "EG30.0", "icd10_code": "L739", "icd10_title": "Follicular disorder, unspecified" }, { "from_icd11": "MG44.1Z", "icd10_code": "R6250", "icd10_title": "Unspecified lack of expected normal physiological development in childhood" }, { "from_icd11": "MG44.1Z", "icd10_code": "R6259", "icd10_title": "Other lack of expected normal physiological development in childhood" }, { "from_icd11": "MG44.1Z", "icd10_code": "R6251", "icd10_title": "Failure to thrive (child)" }, { "from_icd11": "MG44.1Z", "icd10_code": "R6252", "icd10_title": "Short stature (child)" }, { "from_icd11": "MG44.1Z", "icd10_code": "R62", "icd10_title": "Lack of expected normal physiological development in childhood and adults" }, { "from_icd11": "MG44.1Z", "icd10_code": "R628", "icd10_title": "" }, { "from_icd11": "MG44.1Z", "icd10_code": "R629", "icd10_title": "" }, { "from_icd11": "6A00.Z", "icd10_code": "F79", "icd10_title": "Unspecified intellectual disabilities" }, { "from_icd11": "6A00.Z", "icd10_code": "F78", "icd10_title": "Other intellectual disabilities" }, { "from_icd11": "6A00.Z", "icd10_code": "F70-F79", "icd10_title": "" }, { "from_icd11": "6A00.Z", "icd10_code": "F780", "icd10_title": "" } ]	S0101XA	Laceration without foreign body of scalp, initial encounter
MM is considered to be the second most common hematologic malignancy after non-Hodgkin's lymphoma. This article reports the case of a 45-year-old Saudi Arabian man with MM, osteolytic lesions, and vertebral fractures. To our knowledge, this is the first case in Saudi Arabia discussing the surgical intervention for spinal lesions for multiple myeloma. Because MM is highly sensitive to radiotherapy, a few studies in the literature recommend combined radiotherapy with high-dose steroids as first-line therapy . In contrast, several reports have attempted surgical decompression and recommended early surgical decompression followed by radiotherapy or chemotherapy . Our patient underwent chemotherapy and bone marrow transplantation and subsequently was improved, but the hospital's neurosurgeons performed vertebroplasty of the T8 vertebra, and during the vertebroplasty, a bone biopsy was obtained. The patient's lower back pain was relieved. The internal medicine department at Aseer Hospital initiated anti-inflammatory, anticoagulant, and antibiotic medications to prevent complications. The patient received four rounds of VAD chemotherapy, and he underwent a bone marrow transplant. M-spike subsequently decreased from 1.10 to 0.22 g/dL by serum protein electrophoresis. To evaluate the vertebroplasty procedure, Table 3 shows the existing literature on vertebroplasty outcomes in patients with multiple myeloma.	4.03125	0.964844	sec[2]/p[5]	en	0.999998	PMC9904514	https://doi.org/10.7759/cureus.33505	[ "vertebroplasty", "radiotherapy", "chemotherapy", "bone", "this", "saudi", "lesions", "multiple", "myeloma", "literature" ]	[ { "code": "QB96", "title": "Contact with health services for radiotherapy session" }, { "code": "EL63", "title": "Radionecrosis of skin due to therapeutic ionizing irradiation" }, { "code": "EL61", "title": "Chronic radiodermatitis following radiotherapy" }, { "code": "PK81.C", "title": "Radiation therapy associated with injury or harm in therapeutic use" }, { "code": "2C3Y", "title": "Other specified malignant neoplasms of skin" }, { "code": "QB97", "title": "Contact with health services for chemotherapy session for neoplasm" }, { "code": "QC05.Y", "title": "Other specified prophylactic measures" }, { "code": "QB9Y", "title": "Other specified contact with health services for nonsurgical interventions not involving devices" }, { "code": "3B64.1Y", "title": "Other specified acquired thrombocytopenia" }, { "code": "QC48.Y", "title": "Other specified personal history of medical treatment" } ]	=== ICD-11 CODES FOUND === [QB96] Contact with health services for radiotherapy session Also known as: Contact with health services for radiotherapy session \| admission for radiotherapy [EL63] Radionecrosis of skin due to therapeutic ionizing irradiation Definition: Necrosis and ulceration of skin attributable to radiotherapy Also known as: Radionecrosis of skin due to therapeutic ionizing irradiation \| Ulceration of skin due to radiotherapy \| Radionecrosis of skin due to radiotherapy [EL61] Chronic radiodermatitis following radiotherapy Definition: The late cutaneous sequelae of the therapeutic use of ionising radiation. It may take five to ten years to develop and is characterised by cutaneous atrophy, fibrosis, dyspigmentation, alopecia and telangiectasia with associated damage to underlying subcutaneous fat. Also known as: Chronic radiodermatitis following radiotherapy \| Late radiation reaction \| Telangiectasia following radiotherapy \| Poikiloderma following radiotherapy \| Radiation keratosis following radiotherapy [PK81.C] Radiation therapy associated with injury or harm in therapeutic use Also known as: Radiation therapy associated with injury or harm in therapeutic use \| complication during or following radiotherapy \| radiotherapy associated with abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure \| therapeutic ionizing radiation associated with injury or harm \| radiotherapy associated with injury or harm in therapeutic use Excludes: Circumstances associated with a surgical or other medical procedure influencing the episode of care, without injury or harm [2C3Y] Other specified malignant neoplasms of skin Also known as: Other specified malignant neoplasms of skin \| Malignant neoplasm of eyelid NOS \| Malignant pilonidal cyst \| Radiotherapy-induced skin malignancy \| Cutaneous carcinoma [QB97] Contact with health services for chemotherapy session for neoplasm Also known as: Contact with health services for chemotherapy session for neoplasm \| antineoplastic chemotherapy regimen \| cancer chemotherapy regimen \| maintenance chemotherapy for neoplasm \| neoplasm chemotherapy [QC05.Y] Other specified prophylactic measures Also known as: Other specified prophylactic measures \| Other prophylactic chemotherapy \| chemoprophylaxis \| prophylactic chemotherapy \| Systemic prophylactic chemotherapy [QB9Y] Other specified contact with health services for nonsurgical interventions not involving devices Also known as: Other specified contact with health services for nonsurgical interventions not involving devices \| Chemotherapy other than for neoplasm \| admission for chemotherapy administration other than for neoplasm \| chemotherapy regimen other than for neoplasm \| drug therapy other than for neoplasm [3B64.1Y] Other specified acquired thrombocytopenia Also known as: Other specified acquired thrombocytopenia \| Acquired thrombocytopenia specified as refractory \| Chemotherapy thrombocytopaenia \| Liver thrombocytopaenia [QC48.Y] Other specified personal history of medical treatment Also known as: Other specified personal history of medical treatment \| Personal history of contraception \| history of contraception \| Personal history of long-term use of medicaments other than anticoagulants \| personal history of long term current use of medicaments === GRAPH WALKS === --- Walk 1 --- [QB96] Contact with health services for radiotherapy session --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices --CHILD--> [QB91] Contact with health services for piercing of body site other than ear --- Walk 2 --- [QB96] Contact with health services for radiotherapy session --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices --CHILD--> [QB90] Contact with health services for ear piercing --- Walk 3 --- [EL63] Radionecrosis of skin due to therapeutic ionizing irradiation Def: Necrosis and ulceration of skin attributable to radiotherapy... --PARENT--> [?] Adverse cutaneous effects of therapeutic ionizing irradiation --PARENT--> [?] Postprocedural disorders of the skin Def: This group of disorders incorporates drug eruptions, other cutaneous side effects of medication and adverse reactions to medical and surgical interventions.... --- Walk 4 --- [EL63] Radionecrosis of skin due to therapeutic ionizing irradiation Def: Necrosis and ulceration of skin attributable to radiotherapy... --PARENT--> [?] Adverse cutaneous effects of therapeutic ionizing irradiation --RELATED_TO--> [?] Oral mucositis due to radiotherapy Def: This is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer, due to the use o... --- Walk 5 --- [EL61] Chronic radiodermatitis following radiotherapy Def: The late cutaneous sequelae of the therapeutic use of ionising radiation. It may take five to ten years to develop and is characterised by cutaneous atrophy, fibrosis, dyspigmentation, alopecia and te... --PARENT--> [?] Adverse cutaneous effects of therapeutic ionizing irradiation --CHILD--> [EL60] Acute radiodermatitis following radiotherapy Def: The reaction of the skin, and in particular the epidermis, to acute exposure to ionising radiation directed at the skin for therapeutic purposes. It manifests as inflammation, erosion and crusting.... --- Walk 6 --- [EL61] Chronic radiodermatitis following radiotherapy Def: The late cutaneous sequelae of the therapeutic use of ionising radiation. It may take five to ten years to develop and is characterised by cutaneous atrophy, fibrosis, dyspigmentation, alopecia and te... --PARENT--> [?] Adverse cutaneous effects of therapeutic ionizing irradiation --CHILD--> [EL60] Acute radiodermatitis following radiotherapy Def: The reaction of the skin, and in particular the epidermis, to acute exposure to ionising radiation directed at the skin for therapeutic purposes. It manifests as inflammation, erosion and crusting....	[ "[QB96] Contact with health services for radiotherapy session\n --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices\n --CHILD--> [QB91] Contact with health services for piercing of body site other than ear", "[QB96] Contact with health services for radiotherapy session\n --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices\n --CHILD--> [QB90] Contact with health services for ear piercing", "[EL63] Radionecrosis of skin due to therapeutic ionizing irradiation\n Def: Necrosis and ulceration of skin attributable to radiotherapy...\n --PARENT--> [?] Adverse cutaneous effects of therapeutic ionizing irradiation\n --PARENT--> [?] Postprocedural disorders of the skin\n Def: This group of disorders incorporates drug eruptions, other cutaneous side effects of medication and adverse reactions to medical and surgical interventions....", "[EL63] Radionecrosis of skin due to therapeutic ionizing irradiation\n Def: Necrosis and ulceration of skin attributable to radiotherapy...\n --PARENT--> [?] Adverse cutaneous effects of therapeutic ionizing irradiation\n --RELATED_TO--> [?] Oral mucositis due to radiotherapy\n Def: This is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer, due to the use o...", "[EL61] Chronic radiodermatitis following radiotherapy\n Def: The late cutaneous sequelae of the therapeutic use of ionising radiation. It may take five to ten years to develop and is characterised by cutaneous atrophy, fibrosis, dyspigmentation, alopecia and te...\n --PARENT--> [?] Adverse cutaneous effects of therapeutic ionizing irradiation\n --CHILD--> [EL60] Acute radiodermatitis following radiotherapy\n Def: The reaction of the skin, and in particular the epidermis, to acute exposure to ionising radiation directed at the skin for therapeutic purposes. It manifests as inflammation, erosion and crusting....", "[EL61] Chronic radiodermatitis following radiotherapy\n Def: The late cutaneous sequelae of the therapeutic use of ionising radiation. It may take five to ten years to develop and is characterised by cutaneous atrophy, fibrosis, dyspigmentation, alopecia and te...\n --PARENT--> [?] Adverse cutaneous effects of therapeutic ionizing irradiation\n --CHILD--> [EL60] Acute radiodermatitis following radiotherapy\n Def: The reaction of the skin, and in particular the epidermis, to acute exposure to ionising radiation directed at the skin for therapeutic purposes. It manifests as inflammation, erosion and crusting...." ]	QB96	Contact with health services for radiotherapy session	[ { "from_icd11": "QB96", "icd10_code": "Z510", "icd10_title": "Encounter for antineoplastic radiation therapy" }, { "from_icd11": "QB96", "icd10_code": "Z51", "icd10_title": "Encounter for other aftercare and medical care" }, { "from_icd11": "EL63", "icd10_code": "L598", "icd10_title": "Other specified disorders of the skin and subcutaneous tissue related to radiation" }, { "from_icd11": "EL61", "icd10_code": "L581", "icd10_title": "Chronic radiodermatitis" }, { "from_icd11": "PK81.C", "icd10_code": "Y842", "icd10_title": "Radiological procedure and radiotherapy as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure" }, { "from_icd11": "QB97", "icd10_code": "Z5111", "icd10_title": "Encounter for antineoplastic chemotherapy" }, { "from_icd11": "QB97", "icd10_code": "Z5112", "icd10_title": "Encounter for antineoplastic immunotherapy" }, { "from_icd11": "QB97", "icd10_code": "Z511", "icd10_title": "Encounter for antineoplastic chemotherapy and immunotherapy" }, { "from_icd11": "QB9Y", "icd10_code": "Z5181", "icd10_title": "Encounter for therapeutic drug level monitoring" }, { "from_icd11": "QC48.Y", "icd10_code": "Z794", "icd10_title": "Long term (current) use of insulin" }, { "from_icd11": "QC48.Y", "icd10_code": "Z7902", "icd10_title": "Long term (current) use of antithrombotics/antiplatelets" }, { "from_icd11": "QC48.Y", "icd10_code": "Z7982", "icd10_title": "Long term (current) use of aspirin" }, { "from_icd11": "QC48.Y", "icd10_code": "Z7984", "icd10_title": "Long term (current) use of oral hypoglycemic drugs" }, { "from_icd11": "QC48.Y", "icd10_code": "Z79899", "icd10_title": "Other long term (current) drug therapy" } ]	Z510	Encounter for antineoplastic radiation therapy
Laboratory test results included erythrocyte sedimentation rate (Westergren method) 23 mm/h (normal: 3–15 mm/h), hemoglobin 12.2 g/dL, hematocrit 38.7% (mean corpuscular volume 93.9 fL, mean corpuscular hemoglobin [MCH] 29.6 pg, MCH concentration 31.5 g/dL). White blood cell count was 3980/mm3 and platelet count was 230,000/mm3. Urinalysis, liver, and renal function tests; lipid tests; and thyroid function tests were normal. C-reactive protein level was 0.75 mg/dL (normal: < 0.14 mg/dL), soluble interleukin-2 receptor was 896 U/mL (normal: 122–496 U/mL), and creatine kinase was normal. Immune function analysis showed elevated rheumatoid factor (RF) at 56.3 IU/L (normal: < 13 IU/L) and slightly elevated serum matrix metalloproteinase-3 (MMP-3) at 60.1 ng/mL (17.3–59.7 ng/mL). Levels of anti-cyclic citrullinated peptide (anti-CCP) antibody were elevated at 67.3 U/mL (normal: < 4.5 U/mL), but all other antibodies tested, including anti-nuclear, anti-dsDNA, anti-Sm, anti-RNP, anti-SS-A, and anti-SS-B antibodies, were not elevated. M-paraproteinemia was not detected. Serum was positive for anti-HTLV-1 antibody by chemiluminescence enzyme immunoassay. HTLV-1 proviral load (PVL) was 10.56 copies per 100 peripheral blood cells. An anti-HIV antibody test was negative. Anti-hepatitis B virus (HBV) core and anti-HBV surface antibody tests were positive, but HBV surface antigen and HBV DNA tests were negative.	4.148438	0.67334	sec[1]/p[3]	en	0.999997	PMC10163739	https://doi.org/10.1186/s12891-023-06461-3	[ "anti", "antibody", "function", "hemoglobin", "mean", "corpuscular", "blood", "count", "serum", "antibodies" ]	[ { "code": "JA86.Y", "title": "Maternal care for other specified fetal problems" }, { "code": "MB23.1", "title": "Antisocial behaviour" }, { "code": "3B4Z", "title": "Coagulation defects, unspecified" }, { "code": "4A45.Z", "title": "Antiphospholipid syndrome, unspecified" }, { "code": "4A43.Y", "title": "Other specified overlap non-organ specific systemic autoimmune disease" }, { "code": "MA14.14", "title": "Anti-nuclear antibody positive" }, { "code": "MA14.13", "title": "Anti-nuclear antibody negative" }, { "code": "JA86.0", "title": "Maternal care for red cell antibodies" }, { "code": "MA14.1C", "title": "Raised antibody titre" }, { "code": "DD91.Z", "title": "Irritable bowel syndrome or functional bowel disorders, unspecified" } ]	=== ICD-11 CODES FOUND === [JA86.Y] Maternal care for other specified fetal problems Also known as: Maternal care for other specified fetal problems \| Maternal care for other isoimmunization \| Isoimmunization NOS \| maternal antibodies NOS \| pregnancy management affected by incompatibility of blood groups NOS [MB23.1] Antisocial behaviour Definition: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated. Also known as: Antisocial behaviour \| Child or adolescent antisocial behaviour [3B4Z] Coagulation defects, unspecified Also known as: Coagulation defects, unspecified \| blood clotting disturbance \| blood clotting defect \| blood clotting factor deficiency \| clotting abnormality [4A45.Z] Antiphospholipid syndrome, unspecified Also known as: Antiphospholipid syndrome, unspecified \| Antiphospholipid syndrome \| Hughes syndrome \| Anticardiolipin syndrome [4A43.Y] Other specified overlap non-organ specific systemic autoimmune disease Also known as: Other specified overlap non-organ specific systemic autoimmune disease \| Antisynthetase syndrome \| Reynolds syndrome \| Syndromic multisystem autoimmune disease due to ITCH deficiency \| Eosinophilia myalgia syndrome [MA14.14] Anti-nuclear antibody positive Also known as: Anti-nuclear antibody positive \| ANA - [anti-nuclear antibody] positive [MA14.13] Anti-nuclear antibody negative Also known as: Anti-nuclear antibody negative \| ANA - [anti-nuclear antibody] negative [JA86.0] Maternal care for red cell antibodies Definition: Maternal care for rhesus or other isoimmunization Also known as: Maternal care for red cell antibodies \| Maternal care for rhesus isoimmunization \| Rh factor immunization affecting management of pregnancy \| Rh incompatibility \| Rh incompatibility with hydrops fetalis [MA14.1C] Raised antibody titre Also known as: Raised antibody titre \| antibody titre above reference range \| high antibody titre \| increased antibody titre Excludes: isoimmunization, in pregnancy affecting fetus or newborn [DD91.Z] Irritable bowel syndrome or functional bowel disorders, unspecified Also known as: Irritable bowel syndrome or functional bowel disorders, unspecified \| Irritable bowel syndrome or certain specified functional bowel disorders \| Functional intestinal disorders NOS === GRAPH WALKS === --- Walk 1 --- [JA86.Y] Maternal care for other specified fetal problems --PARENT--> [JA86] Maternal care for other fetal problems Def: A condition characterised by the provision of health interventions to the mother due to any other issue that is either suspected or known to be present in the fetus.... --CHILD--> [JA86.2] Maternal care for signs of fetal hypoxia --- Walk 2 --- [JA86.Y] Maternal care for other specified fetal problems --PARENT--> [JA86] Maternal care for other fetal problems Def: A condition characterised by the provision of health interventions to the mother due to any other issue that is either suspected or known to be present in the fetus.... --CHILD--> [JA86.2] Maternal care for signs of fetal hypoxia --- Walk 3 --- [MB23.1] Antisocial behaviour Def: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated.... --PARENT--> [MB23] Symptoms or signs involving appearance or behaviour --CHILD--> [MB23.2] Avoidance behaviour Def: The act of keeping away from circumstances, situations, or stimuli that cause anxiety or other negative emotions in the individual.... --- Walk 4 --- [MB23.1] Antisocial behaviour Def: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated.... --PARENT--> [MB23] Symptoms or signs involving appearance or behaviour --CHILD--> [MB23.1] Antisocial behaviour Def: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated.... --- Walk 5 --- [3B4Z] Coagulation defects, unspecified --PARENT--> [?] Coagulation defects --CHILD--> [3B4Z] Coagulation defects, unspecified --- Walk 6 --- [3B4Z] Coagulation defects, unspecified --PARENT--> [?] Coagulation defects --CHILD--> [?] Haemorrhagic diseases due to acquired coagulation factor defects Def: Any disease caused by determinants arising after birth. These diseases are characterised by abnormal coagulation of the blood....	[ "[JA86.Y] Maternal care for other specified fetal problems\n --PARENT--> [JA86] Maternal care for other fetal problems\n Def: A condition characterised by the provision of health interventions to the mother due to any other issue that is either suspected or known to be present in the fetus....\n --CHILD--> [JA86.2] Maternal care for signs of fetal hypoxia", "[JA86.Y] Maternal care for other specified fetal problems\n --PARENT--> [JA86] Maternal care for other fetal problems\n Def: A condition characterised by the provision of health interventions to the mother due to any other issue that is either suspected or known to be present in the fetus....\n --CHILD--> [JA86.2] Maternal care for signs of fetal hypoxia", "[MB23.1] Antisocial behaviour\n Def: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated....\n --PARENT--> [MB23] Symptoms or signs involving appearance or behaviour\n --CHILD--> [MB23.2] Avoidance behaviour\n Def: The act of keeping away from circumstances, situations, or stimuli that cause anxiety or other negative emotions in the individual....", "[MB23.1] Antisocial behaviour\n Def: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated....\n --PARENT--> [MB23] Symptoms or signs involving appearance or behaviour\n --CHILD--> [MB23.1] Antisocial behaviour\n Def: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated....", "[3B4Z] Coagulation defects, unspecified\n --PARENT--> [?] Coagulation defects\n --CHILD--> [3B4Z] Coagulation defects, unspecified", "[3B4Z] Coagulation defects, unspecified\n --PARENT--> [?] Coagulation defects\n --CHILD--> [?] Haemorrhagic diseases due to acquired coagulation factor defects\n Def: Any disease caused by determinants arising after birth. These diseases are characterised by abnormal coagulation of the blood...." ]	JA86.Y	Maternal care for other specified fetal problems	[ { "from_icd11": "JA86.Y", "icd10_code": "O26841 ", "icd10_title": "" }, { "from_icd11": "JA86.Y", "icd10_code": "O26843 ", "icd10_title": "" }, { "from_icd11": "JA86.Y", "icd10_code": "O26849 ", "icd10_title": "" }, { "from_icd11": "JA86.Y", "icd10_code": "O3680X0 ", "icd10_title": "" }, { "from_icd11": "3B4Z", "icd10_code": "D688", "icd10_title": "Other specified coagulation defects" }, { "from_icd11": "3B4Z", "icd10_code": "D689", "icd10_title": "Coagulation defect, unspecified" }, { "from_icd11": "3B4Z", "icd10_code": "D699", "icd10_title": "Hemorrhagic condition, unspecified" }, { "from_icd11": "3B4Z", "icd10_code": "D698", "icd10_title": "Other specified hemorrhagic conditions" }, { "from_icd11": "3B4Z", "icd10_code": "D65-D69", "icd10_title": "" }, { "from_icd11": "3B4Z", "icd10_code": "D69", "icd10_title": "Purpura and other hemorrhagic conditions" }, { "from_icd11": "4A45.Z", "icd10_code": "D6861", "icd10_title": "Antiphospholipid syndrome" }, { "from_icd11": "4A45.Z", "icd10_code": "D6869", "icd10_title": "Other thrombophilia" }, { "from_icd11": "4A45.Z", "icd10_code": "D6862", "icd10_title": "Lupus anticoagulant syndrome" }, { "from_icd11": "4A45.Z", "icd10_code": "D686", "icd10_title": "Other thrombophilia" }, { "from_icd11": "JA86.0", "icd10_code": "O360930", "icd10_title": "Maternal care for other rhesus isoimmunization, third trimester, not applicable or unspecified" } ]	O26841
His 12 lead electrocardiogram (ECG) showed atrial flutter with 1:1 conduction, at 200 beats per minute, with a morphology consistent with typical cavotricuspid isthmus (CTI) flutter . Systolic blood pressure was 90 mmHg. Intravenous metoprolol was initially trialled, but caused hypotension, so he proceeded to receive direct current cardioversion, which successfully reverted him to sinus rhythm. His sinus rhythm ECG is shown in Fig. 2 . His echocardiogram was normal. He was discharged on apixaban 5 mg tablet twice daily and diltiazem 180 mg controlled release daily, with plans for elective CTI ablation. The diltiazem dose was chosen with consideration of bradycardia (heart rate 45 bpm) and hypotension (BP 100/60) at the time of discharge. Fig. 1 12 lead electrocardiogram at presentation, demonstrating atrial flutter with 1:1 atrioventricular conduction. Arrows in lead III mark the flutter waves, demonstrating negative flutter waves in this lead, consistent with typical cavotricuspid isthmus (CTI) flutter, a counterclockwise macro re-entrant circuit in the right atrium. Due to aberrant conduction, the axis of this electrocardiogram is “north-west” or “extreme axis deviation” and there is an atypical right bundle branch block appearance Fig. 2 12 lead electrocardiogram in sinus rhythm. Normal sinus P waves, normal PR interval, normal QRS duration, normal QRS axis, normal QT interval, no T wave changes	4.023438	0.97168	sec[1]/p[1]	en	0.999997	37464369	https://doi.org/10.1186/s13256-023-03947-5	[ "flutter", "lead", "electrocardiogram", "sinus", "conduction", "rhythm", "waves", "axis", "atrial", "consistent" ]	[ { "code": "MB47.5", "title": "Fasciculation" }, { "code": "9C85.02", "title": "Inappropriate saccades" }, { "code": "BC81.2Z", "title": "Macro reentrant atrial tachycardia, unspecified" }, { "code": "BC71.0Y", "title": "Other specified ventricular tachycardia" }, { "code": "BC81.20", "title": "Cavotricuspid isthmus dependent macroreentry tachycardia" }, { "code": "NE61", "title": "Harmful effects of or exposure to noxious substances, chiefly nonmedicinal as to source, not elsewhere classified" }, { "code": "CA60.Y/PB36&XB17", "title": "Lead miner lung" }, { "code": "MA13.00", "title": "Abnormal level of lead in blood" }, { "code": "8D43.1", "title": "Cognitive impairment due to toxicity" }, { "code": "8D43.0Y&XM0ZH6", "title": "Encephalopathy due to lead" } ]	=== ICD-11 CODES FOUND === [MB47.5] Fasciculation Also known as: Fasciculation \| flickering muscles \| fluttering muscles \| muscle fasciculation \| muscular fasciculation [9C85.02] Inappropriate saccades Also known as: Inappropriate saccades \| Saccadic intrusions and oscillations \| Square-wave jerks, 0.1-0.4 degrees \| Macrosquare-wave jerks \| Square-wave pulses, >0.5 degrees Includes: Saccadic intrusions and oscillations [BC81.2Z] Macro reentrant atrial tachycardia, unspecified Also known as: Macro reentrant atrial tachycardia, unspecified \| Macro reentrant atrial tachycardia \| MRAT - [macro re-entrant atrial tachycardia] \| intra-atrial re-entry tachycardia \| Atrial flutter NOS [BC71.0Y] Other specified ventricular tachycardia Also known as: Other specified ventricular tachycardia \| Monomorphic ventricular tachycardia \| Secondary monomorphic ventricular tachycardia associated with diseases classified elsewhere \| Left outflow tract ventricular tachycardia \| Idiopathic fascicular ventricular tachycardia [BC81.20] Cavotricuspid isthmus dependent macroreentry tachycardia Definition: A macro re-entrant atrial tachycardia that rotates around the tricuspid annulus. Also known as: Cavotricuspid isthmus dependent macroreentry tachycardia \| Cavotricuspid isthmus dependent reentry atrial tachycardia \| Cavotricuspid isthmus dependent macroreentry tachycardia, clockwise \| Atypical atrial flutter clockwise \| Cavotricuspid isthmus dependent macroreentry tachycardia, counterclockwise Includes: Idiopathic neonatal atrial flutter [NE61] Harmful effects of or exposure to noxious substances, chiefly nonmedicinal as to source, not elsewhere classified Also known as: Harmful effects of or exposure to noxious substances, chiefly nonmedicinal as to source, not elsewhere classified \| Harmful effects of or exposure to noxious substances chiefly nonmedicinal as to source, alcohols \| alcohol poisoning \| alcohol toxicity \| Harmful effects of or exposure to noxious substances chiefly nonmedicinal as to source, Ethanol Excludes: corrosions \| Bacterial foodborne intoxications [MA13.00] Abnormal level of lead in blood Definition: Abnormal level of lead in blood in those who have been exposed to lead and who require management. Also known as: Abnormal level of lead in blood Excludes: Harmful effects of or exposure to noxious substances, Substances chiefly nonmedicinal as to source, Metals [8D43.1] Cognitive impairment due to toxicity Definition: These are conditions of impaired cognition due to the toxicity of substances. Also known as: Cognitive impairment due to toxicity \| Cognitive impairment due to lead toxicity === GRAPH WALKS === --- Walk 1 --- [MB47.5] Fasciculation --PARENT--> [MB47] Abnormality of tonus or reflex --CHILD--> [MB47.1] Abnormal posture --- Walk 2 --- [MB47.5] Fasciculation --PARENT--> [MB47] Abnormality of tonus or reflex --CHILD--> [MB47.2] Clonus Def: A series of involuntary muscle contractions and relaxations... --- Walk 3 --- [9C85.02] Inappropriate saccades --PARENT--> [9C85.0] Anomalies of saccadic eye movements --CHILD--> [9C85.02] Inappropriate saccades --- Walk 4 --- [9C85.02] Inappropriate saccades --PARENT--> [9C85.0] Anomalies of saccadic eye movements --CHILD--> [9C85.01] Disorders of the saccadic step --- Walk 5 --- [BC81.2Z] Macro reentrant atrial tachycardia, unspecified --PARENT--> [BC81.2] Macro reentrant atrial tachycardia Def: An atrial arrhythmia in which there is intra-atrial reentry or circus movement around a fixed or functional central obstacle. The central obstacle may consist of normal (e.g. valves) or abnormal (e.g.... --CHILD--> [BC81.20] Cavotricuspid isthmus dependent macroreentry tachycardia Def: A macro re-entrant atrial tachycardia that rotates around the tricuspid annulus.... --- Walk 6 --- [BC81.2Z] Macro reentrant atrial tachycardia, unspecified --PARENT--> [BC81.2] Macro reentrant atrial tachycardia Def: An atrial arrhythmia in which there is intra-atrial reentry or circus movement around a fixed or functional central obstacle. The central obstacle may consist of normal (e.g. valves) or abnormal (e.g.... --CHILD--> [BC81.21] Non-scar, non-isthmus dependent macro reentrant atrial tachycardia Def: A macro re-entrant atrial tachycardia coursing around a normal cardiac structure (except the cavotricuspid isthmus) such as the mitral valve annulus, or superior caval vein....	[ "[MB47.5] Fasciculation\n --PARENT--> [MB47] Abnormality of tonus or reflex\n --CHILD--> [MB47.1] Abnormal posture", "[MB47.5] Fasciculation\n --PARENT--> [MB47] Abnormality of tonus or reflex\n --CHILD--> [MB47.2] Clonus\n Def: A series of involuntary muscle contractions and relaxations...", "[9C85.02] Inappropriate saccades\n --PARENT--> [9C85.0] Anomalies of saccadic eye movements\n --CHILD--> [9C85.02] Inappropriate saccades", "[9C85.02] Inappropriate saccades\n --PARENT--> [9C85.0] Anomalies of saccadic eye movements\n --CHILD--> [9C85.01] Disorders of the saccadic step", "[BC81.2Z] Macro reentrant atrial tachycardia, unspecified\n --PARENT--> [BC81.2] Macro reentrant atrial tachycardia\n Def: An atrial arrhythmia in which there is intra-atrial reentry or circus movement around a fixed or functional central obstacle. The central obstacle may consist of normal (e.g. valves) or abnormal (e.g....\n --CHILD--> [BC81.20] Cavotricuspid isthmus dependent macroreentry tachycardia\n Def: A macro re-entrant atrial tachycardia that rotates around the tricuspid annulus....", "[BC81.2Z] Macro reentrant atrial tachycardia, unspecified\n --PARENT--> [BC81.2] Macro reentrant atrial tachycardia\n Def: An atrial arrhythmia in which there is intra-atrial reentry or circus movement around a fixed or functional central obstacle. The central obstacle may consist of normal (e.g. valves) or abnormal (e.g....\n --CHILD--> [BC81.21] Non-scar, non-isthmus dependent macro reentrant atrial tachycardia\n Def: A macro re-entrant atrial tachycardia coursing around a normal cardiac structure (except the cavotricuspid isthmus) such as the mitral valve annulus, or superior caval vein...." ]	MB47.5	Fasciculation	[ { "from_icd11": "MB47.5", "icd10_code": "R253", "icd10_title": "Fasciculation" }, { "from_icd11": "9C85.02", "icd10_code": "H49-H52", "icd10_title": "" }, { "from_icd11": "BC81.2Z", "icd10_code": "I471", "icd10_title": "Supraventricular tachycardia" }, { "from_icd11": "BC81.20", "icd10_code": "I484", "icd10_title": "Atypical atrial flutter" }, { "from_icd11": "BC81.20", "icd10_code": "I483", "icd10_title": "Typical atrial flutter" }, { "from_icd11": "NE61", "icd10_code": "T5802XA", "icd10_title": "Toxic effect of carbon monoxide from motor vehicle exhaust, intentional self-harm, initial encounter" }, { "from_icd11": "NE61", "icd10_code": "T550X2A", "icd10_title": "Toxic effect of soaps, intentional self-harm, initial encounter" }, { "from_icd11": "NE61", "icd10_code": "T61781A", "icd10_title": "Other shellfish poisoning, accidental (unintentional), initial encounter" }, { "from_icd11": "NE61", "icd10_code": "T551X2A", "icd10_title": "Toxic effect of detergents, intentional self-harm, initial encounter" }, { "from_icd11": "NE61", "icd10_code": "T5891XA", "icd10_title": "Toxic effect of carbon monoxide from unspecified source, accidental (unintentional), initial encounter" }, { "from_icd11": "NE61", "icd10_code": "T63711A", "icd10_title": "Toxic effect of contact with venomous marine plant, accidental (unintentional), initial encounter" }, { "from_icd11": "NE61", "icd10_code": "T63712A", "icd10_title": "Toxic effect of contact with venomous marine plant, intentional self-harm, initial encounter" }, { "from_icd11": "NE61", "icd10_code": "T63713A", "icd10_title": "Toxic effect of contact with venomous marine plant, assault, initial encounter" }, { "from_icd11": "NE61", "icd10_code": "T63714A", "icd10_title": "Toxic effect of contact with venomous marine plant, undetermined, initial encounter" }, { "from_icd11": "NE61", "icd10_code": "T63791A", "icd10_title": "Toxic effect of contact with other venomous plant, accidental (unintentional), initial encounter" } ]	R253	Fasciculation
Classically, patients with COVID-19 pneumonia show typical ground glass opacities on CT scans. However, it is important to note that at least 3% of the time, COVID-19 infection can show atypical symptoms like pleural effusion, cavitation, and lung nodules . While the clinical presentation of squamous cell carcinoma associated with sarcoidosis is rare, studies have shown a correlation . In our case, the large mass seen on the CT scan at the time of presentation, looked more like a coincidental finding and the patient did not exhibit any of the B symptoms of cancer. However, it is noteworthy that multiple medical publications have reported atypical pulmonary nodules on radiographic imaging of patients infected with COVID-19. For example, a recent case reports a concurrent solid nodule in a 37-year-old COVID-19 pneumonia patient who was also a renal transplant recipient. The nodule eventually on biopsy turned out to be an adenocarcinoma lung . A similar case report in a healthy 40-year-old male also led to the diagnosis of adenocarcinoma in a patient with COVID-19 infection who presented with multiple bilateral round to elliptical peripheral ground-glass opacities initially attributed to COVID-19 pneumonia and later on biopsy confirmed to be adenocarcinoma of the lung . Therefore, lung carcinoma was one of our first differentials and a CT-guided biopsy was done which fortunately ruled out lung cancer.	4.046875	0.791504	sec[2]/p[2]	en	0.999998	PMC10275395	https://doi.org/10.7759/cureus.39136	[ "covid", "lung", "pneumonia", "biopsy", "adenocarcinoma", "patients", "ground", "glass", "opacities", "however" ]	[ { "code": "RA01.0", "title": "COVID-19, virus identified" }, { "code": "RA02", "title": "Post COVID-19 condition" }, { "code": "RA01", "title": "COVID-19" }, { "code": "RA01.1", "title": "COVID-19, virus not identified" }, { "code": "QA08.5", "title": "Special screening examination for other viral diseases" }, { "code": "CB40.Y", "title": "Other specified diseases of the respiratory system" }, { "code": "LA75.1", "title": "Agenesis of lung" }, { "code": "CA40.Z", "title": "Pneumonia, organism unspecified" }, { "code": "CB41", "title": "Respiratory failure" }, { "code": "NB32.3Y", "title": "Other injury of lung" } ]	=== ICD-11 CODES FOUND === [RA01.0] COVID-19, virus identified Also known as: COVID-19, virus identified \| 2019-new Coronavirus acute respiratory disease (deprecated) \| 2019-nCoV acute respiratory disease [temporary name] (deprecated) \| Coronavirus disease 2019 \| SARS-CoV-2 disease Includes: Coronavirus disease 2019 \| COVID-19 NOS Excludes: Coronavirus infection, unspecified site \| Middle East respiratory syndrome \| Severe acute respiratory syndrome [RA02] Post COVID-19 condition Definition: Post COVID-19 condition occurs in individuals with a history of probable or confirmed SARS CoV-2 infection, usually 3 months from the onset of COVID-19 with symptoms, and that last for at least 2 months and cannot be explained by an alternative diagnosis. Common symptoms include fatigue, shortness of breath, cognitive dysfunction but also others, and generally have an impact on everyday functioning. Symptoms may be new onset following initial recovery from an acute COVID-19 episode or persist fr Also known as: Post COVID-19 condition \| postCOVID condition \| post-COVID-19 condition \| long COVID [RA01] COVID-19 Definition: As definition may evolve, the URL for the Global surveillance document will be added as the short description Also known as: COVID-19 [RA01.1] COVID-19, virus not identified Also known as: COVID-19, virus not identified \| clinically diagnosed COVID-19 \| suspected COVID-19 \| probable COVID-19 \| clinical COVID-19 Excludes: COVID-19, virus identified \| Coronavirus infection, unspecified site \| Special screening examination for other viral diseases [QA08.5] Special screening examination for other viral diseases Also known as: Special screening examination for other viral diseases \| Measles screening \| Poliomyelitis screening \| Rubella screening \| Screening for Dengue fever Includes: Screening for COVID-19 Excludes: Viral intestinal infections \| Special screening examination for infections with a predominantly sexual mode of transmission \| Special screening examination for human immunodeficiency virus [CB40.Y] Other specified diseases of the respiratory system Also known as: Other specified diseases of the respiratory system \| Secondary respiratory disorders \| Respiratory disorders in diseases classified elsewhere \| Diseases of bronchus, not elsewhere classified \| Acquired bronchial diverticulum [LA75.1] Agenesis of lung Definition: This refers to the absence or rudimentary residua of an undeveloped lung. Also known as: Agenesis of lung \| Pulmonary agenesis \| absence of lung \| aplasia of lung \| apulmonism [CA40.Z] Pneumonia, organism unspecified Also known as: Pneumonia, organism unspecified \| Pneumonia \| infectious pneumonia \| PN - [pneumonia] \| lobar pneumonia NOS [CB41] Respiratory failure Definition: Respiratory failure is a life-threatening impairment of oxygenation or carbon dioxide (CO2) elimination. Respiratory failure may occur because of impaired gas exchange, decreased ventilation, or both. The level of oxygen in the blood becomes dangerously low or the level of carbon dioxide becomes dangerously high. Also known as: Respiratory failure \| lung failure NOS \| pulmonary failure Excludes: Acute respiratory distress syndrome \| Respiratory arrest \| Respiratory distress of newborn [NB32.3Y] Other injury of lung Also known as: Other injury of lung \| Haematoma of lung \| Traumatic hydropneumothorax \| Acute traumatic lung congestion \| Rupture of lung === GRAPH WALKS === --- Walk 1 --- [RA01.0] COVID-19, virus identified --EXCLUDES--> [?] Severe acute respiratory syndrome Def: A disease of the respiratory system, caused by an infection with coronavirus. This disease is characterised by fever, headache, cough, myalgia, tachycardia, or diarrhoea. This disease may also lead to... --EXCLUDES--> [?] COVID-19, virus not identified --- Walk 2 --- [RA01.0] COVID-19, virus identified --EXCLUDES--> [?] Coronavirus infection, unspecified site --PARENT--> [?] Viral infection of unspecified site --- Walk 3 --- [RA02] Post COVID-19 condition Def: Post COVID-19 condition occurs in individuals with a history of probable or confirmed SARS CoV-2 infection, usually 3 months from the onset of COVID-19 with symptoms, and that last for at least 2 mont... --PARENT--> [?] International provisional assignment of new diseases of uncertain aetiology and emergency use --PARENT--> [25] Codes for special purposes --- Walk 4 --- [RA02] Post COVID-19 condition Def: Post COVID-19 condition occurs in individuals with a history of probable or confirmed SARS CoV-2 infection, usually 3 months from the onset of COVID-19 with symptoms, and that last for at least 2 mont... --PARENT--> [?] International provisional assignment of new diseases of uncertain aetiology and emergency use --CHILD--> [RA00] Conditions of uncertain aetiology and emergency use --- Walk 5 --- [RA01] COVID-19 Def: As definition may evolve, the URL for the Global surveillance document will be added as the short description... --CHILD--> [RA01.1] COVID-19, virus not identified --EXCLUDES--> [?] Special screening examination for other viral diseases --- Walk 6 --- [RA01] COVID-19 Def: As definition may evolve, the URL for the Global surveillance document will be added as the short description... --CHILD--> [RA01.0] COVID-19, virus identified --EXCLUDES--> [?] Middle East respiratory syndrome Def: A disease caused by an infection with Middle East Respiratory Syndrome coronavirus (MERS-CoA). This disease is characterised by severe acute respiratory illness with fever, cough, and shortness of bre...	[ "[RA01.0] COVID-19, virus identified\n --EXCLUDES--> [?] Severe acute respiratory syndrome\n Def: A disease of the respiratory system, caused by an infection with coronavirus. This disease is characterised by fever, headache, cough, myalgia, tachycardia, or diarrhoea. This disease may also lead to...\n --EXCLUDES--> [?] COVID-19, virus not identified", "[RA01.0] COVID-19, virus identified\n --EXCLUDES--> [?] Coronavirus infection, unspecified site\n --PARENT--> [?] Viral infection of unspecified site", "[RA02] Post COVID-19 condition\n Def: Post COVID-19 condition occurs in individuals with a history of probable or confirmed SARS CoV-2 infection, usually 3 months from the onset of COVID-19 with symptoms, and that last for at least 2 mont...\n --PARENT--> [?] International provisional assignment of new diseases of uncertain aetiology and emergency use\n --PARENT--> [25] Codes for special purposes", "[RA02] Post COVID-19 condition\n Def: Post COVID-19 condition occurs in individuals with a history of probable or confirmed SARS CoV-2 infection, usually 3 months from the onset of COVID-19 with symptoms, and that last for at least 2 mont...\n --PARENT--> [?] International provisional assignment of new diseases of uncertain aetiology and emergency use\n --CHILD--> [RA00] Conditions of uncertain aetiology and emergency use", "[RA01] COVID-19\n Def: As definition may evolve, the URL for the Global surveillance document will be added as the short description...\n --CHILD--> [RA01.1] COVID-19, virus not identified\n --EXCLUDES--> [?] Special screening examination for other viral diseases", "[RA01] COVID-19\n Def: As definition may evolve, the URL for the Global surveillance document will be added as the short description...\n --CHILD--> [RA01.0] COVID-19, virus identified\n --EXCLUDES--> [?] Middle East respiratory syndrome\n Def: A disease caused by an infection with Middle East Respiratory Syndrome coronavirus (MERS-CoA). This disease is characterised by severe acute respiratory illness with fever, cough, and shortness of bre..." ]	RA01.0	COVID-19, virus identified	[ { "from_icd11": "QA08.5", "icd10_code": "Z1159", "icd10_title": "Encounter for screening for other viral diseases" }, { "from_icd11": "QA08.5", "icd10_code": "Z1151", "icd10_title": "Encounter for screening for human papillomavirus (HPV)" }, { "from_icd11": "QA08.5", "icd10_code": "Z115", "icd10_title": "Encounter for screening for other viral diseases" }, { "from_icd11": "LA75.1", "icd10_code": "Q333", "icd10_title": "Agenesis of lung" }, { "from_icd11": "CA40.Z", "icd10_code": "J189", "icd10_title": "Pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J181", "icd10_title": "Lobar pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J188", "icd10_title": "Other pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J168", "icd10_title": "Pneumonia due to other specified infectious organisms" }, { "from_icd11": "CA40.Z", "icd10_code": "J180", "icd10_title": "Bronchopneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J17", "icd10_title": "Pneumonia in diseases classified elsewhere" }, { "from_icd11": "CA40.Z", "icd10_code": "J182", "icd10_title": "Hypostatic pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J16", "icd10_title": "Pneumonia due to other infectious organisms, not elsewhere classified" }, { "from_icd11": "CA40.Z", "icd10_code": "J171", "icd10_title": "" }, { "from_icd11": "CA40.Z", "icd10_code": "J173", "icd10_title": "" }, { "from_icd11": "CA40.Z", "icd10_code": "J178", "icd10_title": "" } ]	Z1159	Encounter for screening for other viral diseases
This boy is the child of a consanguineous union between first cousins of Pakistani descent. At two weeks of age, he presented for circumcision, when blood work was carried out, and high TGs were found. No further details are known. However, at that time, the family in Pakistan was told to avoid high-fat food. The family history is remarkable in that both parents had hyperlipidemia, and the father had bypass surgery by the age of 60 years. One paternal uncle has hyperlipidemia and is on medications but has no cardiovascular complaints. The family moved to Canada in 2006 when he was six years old. He was followed up in the cardiology lipid clinic at the Hospital for Sick Children. His initial lipid profile showed elevated TGs; he was started on a fat-restricted diet and fibrate medication (Lipidil ® ). The diagnosis of LPL deficiency was confirmed via molecular testing, which showed a homozygous nonsense mutation in the LPL gene (Q262X, c.784C>T). The family’s compliance with the diet was insufficient. He continued to have an extremely elevated TG level of 45 mml/L, which ultimately affected his growth and development significantly. By seven years of age, he developed eruptive xanthomata spreading over his body, ears, forearms, and legs. He had no previous history of hospitalization with acute pancreatitis; however, he had frequent episodes of headache and abdominal pain related to eating fatty food.	3.898438	0.983887	sec[2]/sec[5]/p[0]	en	0.999997	37630727	https://doi.org/10.3390/nu15163535	[ "family", "however", "that", "food", "hyperlipidemia", "lipid", "diet", "which", "this", "consanguineous" ]	[ { "code": "QE70.Z", "title": "Problems related to primary support group, including family circumstances, unspecified" }, { "code": "8C74.1Z", "title": "Periodic paralysis, unspecified" }, { "code": "2B90.Y", "title": "Other specified malignant neoplasms of colon" }, { "code": "EE61", "title": "Superficial fibromatoses" }, { "code": "9B70", "title": "Inherited retinal dystrophies" }, { "code": "8A80.Z", "title": "Migraine, unspecified" }, { "code": "QA76", "title": "Medication or substance that is known to be an allergen without injury or harm" }, { "code": "PL13.6", "title": "Medication or substance that is known to be an allergen, as mode of injury or harm" }, { "code": "9C40.A0", "title": "Papilloedema" }, { "code": "PA6Z", "title": "Unintentional fall from unspecified height" } ]	=== ICD-11 CODES FOUND === [QE70.Z] Problems related to primary support group, including family circumstances, unspecified Also known as: Problems related to primary support group, including family circumstances, unspecified \| Problems related to primary support group, including family circumstances \| family problem \| problem related to primary support group \| Problem related to gambling in the family [8C74.1Z] Periodic paralysis, unspecified Also known as: Periodic paralysis, unspecified \| Periodic paralysis \| Westphal disease \| periodic myotonia \| myoplegic dystrophy [2B90.Y] Other specified malignant neoplasms of colon Also known as: Other specified malignant neoplasms of colon \| Neuroendocrine neoplasm of colon \| Colon endocrine neoplasm \| Neuroendocrine carcinoma of colon \| NEC - [neuroendocrine carcinoma] of colon [EE61] Superficial fibromatoses Also known as: Superficial fibromatoses \| Pachydermodactyly \| Camptodactyly or streblodactyly \| Familial camptodactyly \| Sporadic camptodactyly [9B70] Inherited retinal dystrophies Also known as: Inherited retinal dystrophies \| hereditary retinal dystrophies \| Amaurosis - hypertrichosis \| Autosomal dominant late-onset retinal degeneration \| Bothnia retinal dystrophy Includes: Leber congenital amaurosis \| Stargardt disease \| Vitreoretinal dystrophy [8A80.Z] Migraine, unspecified Also known as: Migraine, unspecified \| Migraine [QA76] Medication or substance that is known to be an allergen without injury or harm Definition: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm. Also known as: Medication or substance that is known to be an allergen without injury or harm Excludes: Medication or substance that is known to be an allergen, as mode of injury or harm [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm Also known as: Medication or substance that is known to be an allergen, as mode of injury or harm \| medication error relating to known allergy to drug or substance \| adverse drug event relating to known allergy to drug or substance [9C40.A0] Papilloedema Definition: Optic disc swelling that results from increased intracranial pressure Also known as: Papilloedema \| Optic disc swelling that results from increased intracranial pressure Includes: Optic disc swelling that results from increased intracranial pressure [PA6Z] Unintentional fall from unspecified height Also known as: Unintentional fall from unspecified height \| fall NOS \| accidental fall \| fall causing injury that resulted in death \| fell NOS === GRAPH WALKS === --- Walk 1 --- [QE70.Z] Problems related to primary support group, including family circumstances, unspecified --PARENT--> [QE70] Problems related to primary support group, including family circumstances --CHILD--> [QE70.2] Dependent relative needing care at home --- Walk 2 --- [QE70.Z] Problems related to primary support group, including family circumstances, unspecified --PARENT--> [QE70] Problems related to primary support group, including family circumstances --CHILD--> [QE70.1] Disruption of family by separation or divorce --- Walk 3 --- [8C74.1Z] Periodic paralysis, unspecified --PARENT--> [8C74.1] Periodic paralysis Def: Rare group of neuromuscular disorders that are associated with defects in ion channels. Characterized by intermittent episodes of severe weakness of the limbs usually after heavy exercise, fasting, or... --CHILD--> [8C74.10] Hypokalaemic periodic paralysis Def: Hypokalaemic periodic paralysis (hypoPP) is a muscle channelopathy characterised by episodes of muscle paralysis lasting from a few to 24-48 hours and associated with a fall in blood potassium levels.... --- Walk 4 --- [8C74.1Z] Periodic paralysis, unspecified --PARENT--> [8C74.1] Periodic paralysis Def: Rare group of neuromuscular disorders that are associated with defects in ion channels. Characterized by intermittent episodes of severe weakness of the limbs usually after heavy exercise, fasting, or... --CHILD--> [8C74.1Y] Other specified periodic paralysis --- Walk 5 --- [2B90.Y] Other specified malignant neoplasms of colon --PARENT--> [2B90] Malignant neoplasms of colon Def: Primary malignant neoplasms arising in the colon.... --EXCLUDES--> [?] Malignant neoplasms of appendix Def: A primary malignant neoplasm that affects the appendix.... --- Walk 6 --- [2B90.Y] Other specified malignant neoplasms of colon --PARENT--> [2B90] Malignant neoplasms of colon Def: Primary malignant neoplasms arising in the colon.... --CHILD--> [2B90.2] Malignant neoplasm of transverse colon	[ "[QE70.Z] Problems related to primary support group, including family circumstances, unspecified\n --PARENT--> [QE70] Problems related to primary support group, including family circumstances\n --CHILD--> [QE70.2] Dependent relative needing care at home", "[QE70.Z] Problems related to primary support group, including family circumstances, unspecified\n --PARENT--> [QE70] Problems related to primary support group, including family circumstances\n --CHILD--> [QE70.1] Disruption of family by separation or divorce", "[8C74.1Z] Periodic paralysis, unspecified\n --PARENT--> [8C74.1] Periodic paralysis\n Def: Rare group of neuromuscular disorders that are associated with defects in ion channels. Characterized by intermittent episodes of severe weakness of the limbs usually after heavy exercise, fasting, or...\n --CHILD--> [8C74.10] Hypokalaemic periodic paralysis\n Def: Hypokalaemic periodic paralysis (hypoPP) is a muscle channelopathy characterised by episodes of muscle paralysis lasting from a few to 24-48 hours and associated with a fall in blood potassium levels....", "[8C74.1Z] Periodic paralysis, unspecified\n --PARENT--> [8C74.1] Periodic paralysis\n Def: Rare group of neuromuscular disorders that are associated with defects in ion channels. Characterized by intermittent episodes of severe weakness of the limbs usually after heavy exercise, fasting, or...\n --CHILD--> [8C74.1Y] Other specified periodic paralysis", "[2B90.Y] Other specified malignant neoplasms of colon\n --PARENT--> [2B90] Malignant neoplasms of colon\n Def: Primary malignant neoplasms arising in the colon....\n --EXCLUDES--> [?] Malignant neoplasms of appendix\n Def: A primary malignant neoplasm that affects the appendix....", "[2B90.Y] Other specified malignant neoplasms of colon\n --PARENT--> [2B90] Malignant neoplasms of colon\n Def: Primary malignant neoplasms arising in the colon....\n --CHILD--> [2B90.2] Malignant neoplasm of transverse colon" ]	QE70.Z	Problems related to primary support group, including family circumstances, unspecified	[ { "from_icd11": "QE70.Z", "icd10_code": "Z6379", "icd10_title": "Other stressful life events affecting family and household" }, { "from_icd11": "QE70.Z", "icd10_code": "Z6372", "icd10_title": "Alcoholism and drug addiction in family" }, { "from_icd11": "QE70.Z", "icd10_code": "Z638", "icd10_title": "Other specified problems related to primary support group" }, { "from_icd11": "QE70.Z", "icd10_code": "Z639", "icd10_title": "Problem related to primary support group, unspecified" }, { "from_icd11": "QE70.Z", "icd10_code": "Z637", "icd10_title": "Other stressful life events affecting family and household" }, { "from_icd11": "8C74.1Z", "icd10_code": "G723", "icd10_title": "Periodic paralysis" }, { "from_icd11": "EE61", "icd10_code": "F54", "icd10_title": "Psychological and behavioral factors associated with disorders or diseases classified elsewhere" }, { "from_icd11": "9B70", "icd10_code": "H3552", "icd10_title": "Pigmentary retinal dystrophy" }, { "from_icd11": "9B70", "icd10_code": "H3550", "icd10_title": "Unspecified hereditary retinal dystrophy" }, { "from_icd11": "9B70", "icd10_code": "H3553", "icd10_title": "Other dystrophies primarily involving the sensory retina" }, { "from_icd11": "9B70", "icd10_code": "H3554", "icd10_title": "Dystrophies primarily involving the retinal pigment epithelium" }, { "from_icd11": "9B70", "icd10_code": "H355", "icd10_title": "Hereditary retinal dystrophy" }, { "from_icd11": "8A80.Z", "icd10_code": "G43B0", "icd10_title": "Ophthalmoplegic migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43409", "icd10_title": "Hemiplegic migraine, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A0", "icd10_title": "Cyclical vomiting, in migraine, not intractable" } ]	Z6379	Other stressful life events affecting family and household
However, her fever persisted, and we had difficulty with attaining glycemic control. Her right middle lobe cavity was surgically removed on Day 14 to facilitate glycemic control . The histology revealed a chronic abscess, surrounded by a thick fibrous wall and some necrotic debris, and focal septate fungal hyphae in the lumen, which were positive on Gomori methenamine silver stain, suggestive of aspergillosis . The culture of the surgical lung specimens revealed Aspergillus growth. On Day 17, she started a 2-week course of oral voriconazole. On day 17, her consciousness returned to E4V5M6, and a follow-up brain MRI revealed some regression. After 43 days of hospitalization with 1 month of cysticidal therapy, she regained full consciousness, but her lower limb weakness did not improve. Bedside physical therapy for reconditioning rehabilitation to improve muscle endurance and strength, posture training, endurance training and strengthening training were administered for 3 weeks. She was then discharged to a nursing home near her son’s house, where she continued rehabilitation. Fig. 3 The pathologic findings in the right middle lung. The right middle lobe was surgically removed . Histology revealed a chronic abscess cavity, surrounded by a thick fibrous wall and necrotic debris, and focal septate fungal hyphae in the lumen which were positive on Gomori methenamine silver stain (magnification × [200X])	3.902344	0.981934	sec[1]/p[2]	en	0.999996	33066738	https://doi.org/10.1186/s12879-020-05492-8	[ "middle", "training", "glycemic", "control", "lobe", "cavity", "surgically", "histology", "abscess", "surrounded" ]	[ { "code": "CB40.2", "title": "Pulmonary collapse" }, { "code": "LA8B.21", "title": "Coarctation of aorta" }, { "code": "AB0Z", "title": "Otitis media, unspecified" }, { "code": "AB1Y&XA0G74", "title": "Fistula of middle ear" }, { "code": "2F91.Y&XA0G74", "title": "Neoplasms of unknown behaviour of middle ear" }, { "code": "PA3Z", "title": "Unintentional railway transport injury event of unspecified type" }, { "code": "PB82", "title": "Intentional self-harm by land transport injury event unknown whether traffic or nontraffic" }, { "code": "QB95.6", "title": "Orthoptic training" }, { "code": "PA00&XE6DQ&XE88K", "title": "Pedestrian injured in collision with railway train or railway vehicle, traffic accident" }, { "code": "PA31&XE3S3&XE8YD", "title": "Occupant of railway train or railway vehicle injured by fall in railway train or railway vehicle" } ]	=== ICD-11 CODES FOUND === [CB40.2] Pulmonary collapse Also known as: Pulmonary collapse \| Atelectasis \| lung collapse \| pulmonary atelectasis \| pulmonary collapse with atelectasis Includes: Atelectasis Excludes: Primary atelectasis of newborn \| tuberculous atelectasis, not confirmed \| tuberculous atelectasis, confirmed [LA8B.21] Coarctation of aorta Definition: A congenital cardiovascular malformation in which there is a discrete luminal narrowing of the junction between the aortic arch and the descending aorta. Additional information: 'Coarctation of the aorta' generally indicates a narrowing of the descending thoracic aorta just distal to the left subclavian artery. However, the term may also be accurately used to refer to a region of narrowing anywhere in the thoracic or abdominal aorta. Also known as: Coarctation of aorta \| aortic coarctation \| Preductal coarctation of aorta \| Postductal coarctation of aorta \| Descending thoracic or abdominal aortic coarctation [AB0Z] Otitis media, unspecified Also known as: Otitis media, unspecified \| ear infection \| middle ear infection \| inflammation of the middle ear \| middle ear catarrh [PA3Z] Unintentional railway transport injury event of unspecified type Also known as: Unintentional railway transport injury event of unspecified type \| train accident \| train crash \| Railway accident NOS \| Occupant of railway train or railway vehicle injured in transport accident [PB82] Intentional self-harm by land transport injury event unknown whether traffic or nontraffic Also known as: Intentional self-harm by land transport injury event unknown whether traffic or nontraffic \| intentional collision with tram or streetcar \| intentional collision with motor vehicle \| intentional collision with train \| intentional self-harm by crashing of motor vehicle [QB95.6] Orthoptic training Also known as: Orthoptic training \| admission for orthoptic training === GRAPH WALKS === --- Walk 1 --- [CB40.2] Pulmonary collapse --EXCLUDES--> [?] Respiratory tuberculosis, not confirmed Def: A disease of the respiratory tract, caused by an infection with the bacteria Mycobacterium tuberculosis, which has not been confirmed. This disease is characterised by a chronic cough, and sputum prod... --CHILD--> [?] Tuberculosis of lung, bacteriological or histological examination not done Def: This is a common, and in many cases lethal, infectious disease of the lung caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is with bacteriological and his... --- Walk 2 --- [CB40.2] Pulmonary collapse --EXCLUDES--> [?] Respiratory tuberculosis, confirmed Def: A disease of the respiratory tract, caused by an infection with the bacteria Mycobacterium tuberculosis, which has been confirmed by laboratory testing. This disease is characterised by chronic cough,... --CHILD--> [?] Tuberculosis of lung, confirmed histologically Def: This is a common, and in many cases lethal, infectious disease of the lung caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is confirmed histologically.... --- Walk 3 --- [LA8B.21] Coarctation of aorta Def: A congenital cardiovascular malformation in which there is a discrete luminal narrowing of the junction between the aortic arch and the descending aorta. Additional information: 'Coarctation of the a... --PARENT--> [LA8B.2] Congenital anomaly of aorta or its branches Def: A congenital cardiovascular malformation of the aorta and/or its branches.... --CHILD--> [LA8B.23] Congenital anomaly of descending thoracic or abdominal aorta Def: A congenital cardiovascular malformation of the aorta distal to the aortic arch... --- Walk 4 --- [LA8B.21] Coarctation of aorta Def: A congenital cardiovascular malformation in which there is a discrete luminal narrowing of the junction between the aortic arch and the descending aorta. Additional information: 'Coarctation of the a... --PARENT--> [LA8B.2] Congenital anomaly of aorta or its branches Def: A congenital cardiovascular malformation of the aorta and/or its branches.... --CHILD--> [LA8B.22] Interrupted aortic arch Def: A congenital cardiovascular malformation in which there is an absence of luminal continuity between the ascending and descending aorta. Additional information: this includes luminal atresia with disc... --- Walk 5 --- [AB0Z] Otitis media, unspecified --PARENT--> [?] Otitis media --CHILD--> [?] Suppurative otitis media Def: This involves a perforation (hole) in the tympanic membrane and active bacterial infection within the middle ear space for several weeks or more. There may be enough pus that it drains to the outside ... --- Walk 6 --- [AB0Z] Otitis media, unspecified --PARENT--> [?] Otitis media --CHILD--> [AB00] Acute otitis media	[ "[CB40.2] Pulmonary collapse\n --EXCLUDES--> [?] Respiratory tuberculosis, not confirmed\n Def: A disease of the respiratory tract, caused by an infection with the bacteria Mycobacterium tuberculosis, which has not been confirmed. This disease is characterised by a chronic cough, and sputum prod...\n --CHILD--> [?] Tuberculosis of lung, bacteriological or histological examination not done\n Def: This is a common, and in many cases lethal, infectious disease of the lung caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is with bacteriological and his...", "[CB40.2] Pulmonary collapse\n --EXCLUDES--> [?] Respiratory tuberculosis, confirmed\n Def: A disease of the respiratory tract, caused by an infection with the bacteria Mycobacterium tuberculosis, which has been confirmed by laboratory testing. This disease is characterised by chronic cough,...\n --CHILD--> [?] Tuberculosis of lung, confirmed histologically\n Def: This is a common, and in many cases lethal, infectious disease of the lung caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is confirmed histologically....", "[LA8B.21] Coarctation of aorta\n Def: A congenital cardiovascular malformation in which there is a discrete luminal narrowing of the junction between the aortic arch and the descending aorta.\n\nAdditional information: 'Coarctation of the a...\n --PARENT--> [LA8B.2] Congenital anomaly of aorta or its branches\n Def: A congenital cardiovascular malformation of the aorta and/or its branches....\n --CHILD--> [LA8B.23] Congenital anomaly of descending thoracic or abdominal aorta\n Def: A congenital cardiovascular malformation of the aorta distal to the aortic arch...", "[LA8B.21] Coarctation of aorta\n Def: A congenital cardiovascular malformation in which there is a discrete luminal narrowing of the junction between the aortic arch and the descending aorta.\n\nAdditional information: 'Coarctation of the a...\n --PARENT--> [LA8B.2] Congenital anomaly of aorta or its branches\n Def: A congenital cardiovascular malformation of the aorta and/or its branches....\n --CHILD--> [LA8B.22] Interrupted aortic arch\n Def: A congenital cardiovascular malformation in which there is an absence of luminal continuity between the ascending and descending aorta.\n\nAdditional information: this includes luminal atresia with disc...", "[AB0Z] Otitis media, unspecified\n --PARENT--> [?] Otitis media\n --CHILD--> [?] Suppurative otitis media\n Def: This involves a perforation (hole) in the tympanic membrane and active bacterial infection within the middle ear space for several weeks or more. There may be enough pus that it drains to the outside ...", "[AB0Z] Otitis media, unspecified\n --PARENT--> [?] Otitis media\n --CHILD--> [AB00] Acute otitis media" ]	CB40.2	Pulmonary collapse	[ { "from_icd11": "CB40.2", "icd10_code": "J9811", "icd10_title": "Atelectasis" }, { "from_icd11": "CB40.2", "icd10_code": "J9819", "icd10_title": "Other pulmonary collapse" }, { "from_icd11": "CB40.2", "icd10_code": "J981", "icd10_title": "Pulmonary collapse" }, { "from_icd11": "LA8B.21", "icd10_code": "Q251", "icd10_title": "Coarctation of aorta" }, { "from_icd11": "LA8B.21", "icd10_code": "Q251 ", "icd10_title": "" }, { "from_icd11": "AB0Z", "icd10_code": "H673", "icd10_title": "Otitis media in diseases classified elsewhere, bilateral" }, { "from_icd11": "AB0Z", "icd10_code": "H6690", "icd10_title": "Otitis media, unspecified, unspecified ear" }, { "from_icd11": "AB0Z", "icd10_code": "H6693", "icd10_title": "Otitis media, unspecified, bilateral" }, { "from_icd11": "AB0Z", "icd10_code": "H669", "icd10_title": "Otitis media, unspecified" }, { "from_icd11": "AB0Z", "icd10_code": "H67", "icd10_title": "Otitis media in diseases classified elsewhere" }, { "from_icd11": "AB0Z", "icd10_code": "H670", "icd10_title": "" }, { "from_icd11": "AB0Z", "icd10_code": "H671", "icd10_title": "Otitis media in diseases classified elsewhere, right ear" }, { "from_icd11": "AB0Z", "icd10_code": "H678", "icd10_title": "" }, { "from_icd11": "PB82", "icd10_code": "X811XXA", "icd10_title": "Intentional self-harm by jumping or lying in front of (subway) train, initial encounter" }, { "from_icd11": "PB82", "icd10_code": "X810XXA", "icd10_title": "Intentional self-harm by jumping or lying in front of motor vehicle, initial encounter" } ]	J9811	Atelectasis
The second dog was a nearly 2-year old female, spayed mixed breed dog with a history of a defect in the right upper lip of supposed shooting trauma resulting in the inability of unimpaired feeding. The dog also displayed purulent nasal discharge and was presented to the university clinic by a society for the prevention of cruelty to animals. The dog was fed by hand with small balls formed of canned dog food. On examination the middle third of the right upper lip, approximately 60% of the width and two thirds of the length of the hard palate were missing. Correspondingly, the nasal cavity was visible over approximately two thirds of its length. The mucosa of the nasal cavity was inflamed; hypertrophied and purulent discharge was present. The complete blood count and chemistry profile were within normal limits. Computed tomography (CT) revealed an osseous defect of the right maxilla and the left mandible. Furthermore, multiple injured teeth, retained tooth roots, various bullet fragments in the soft tissue and enlarged retropharyngeal and mandibular lymph nodes were detected on CT. Accordingly, a gunshot injury with secondary chronic rhinitis was diagnosed. Injured teeth, the retained tooth roots and the teeth of the caudal part of the right maxilla were removed in order to plan soft tissue reconstruction. A sample of the nasal cavity was submitted for microbiological culture and sensitivity testing.	3.832031	0.980957	sec[1]/sec[0]/sec[1]/p[0]	en	0.999997	34170418	https://doi.org/10.1007/s10482-021-01605-8	[ "nasal", "cavity", "teeth", "defect", "purulent", "approximately", "thirds", "length", "maxilla", "injured" ]	[ { "code": "MA82.2", "title": "Nasality" }, { "code": "CA0Z", "title": "Upper respiratory tract disorders, unspecified" }, { "code": "CA0Y", "title": "Other specified upper respiratory tract disorders" }, { "code": "LA70.2", "title": "Choanal atresia" }, { "code": "NA00.3&XJ1C6", "title": "Haematoma of nose" }, { "code": "DA08.0", "title": "Dental caries" }, { "code": "1F25.01", "title": "Chronic pulmonary coccidioidomycosis" }, { "code": "DA08.0&XA5R09", "title": "Caries limited to enamel" }, { "code": "CB2Z", "title": "Pleural, diaphragm or mediastinal disorders, unspecified" }, { "code": "DC51.1", "title": "Peritoneal adhesions" } ]	=== ICD-11 CODES FOUND === [MA82.2] Nasality Definition: Nasality (or resonance) refers to the quality of the voice that is determined by the balance of sound vibration in the oral, nasal, and pharyngeal cavities during speech. Abnormal resonance can occur when there is obstruction in one of the cavities, causing hyponasality, or when there is velopharyngeal dysfunction, causing hypernasality. This category should only be assigned when hyponasality or hypernasality is outside the limits of normal variation and results in reduced intelligibility and si Also known as: Nasality \| Hypernasality \| Hyponasality [CA0Z] Upper respiratory tract disorders, unspecified Also known as: Upper respiratory tract disorders, unspecified \| Disorder of the nose, unspecified \| Disease of nose, unspecified \| nasal disease \| Lesion of nose, unspecified [CA0Y] Other specified upper respiratory tract disorders Also known as: Other specified upper respiratory tract disorders \| Acute adenoiditis \| adenoid infection \| Pharyngotonsillitis \| tonsillopharyngitis [LA70.2] Choanal atresia Definition: Any condition in neonates, caused by failure of the nose to correctly develop during the antenatal period. This condition is characterised by narrowing or blockage of the nasal airway by tissue. This condition may also present with chest retraction unless child is breathing through mouth or crying, difficulty breathing, cyanosis, and inability to nurse and breathe at same time. Also known as: Choanal atresia \| choanal fusion \| atresia of nares \| congenital stenosis of nares \| congenital stenosis of choanae [DA08.0] Dental caries Definition: A condition characterised by localised destruction of calcified tissue, initiated on the tooth surface by decalcification of the enamel, followed by the enzymatic lysis of organic structures, resulting in cavity formation. Also known as: Dental caries \| Dental decay \| carious teeth \| dental cavity \| saprodontia Includes: Dental decay [1F25.01] Chronic pulmonary coccidioidomycosis Definition: A chronic form of pulmonary coccidioidomycosis. Pulmonary sequelae occur in approximately 5% of all cases of acute pulmonary coccidioidomycosis. Also known as: Chronic pulmonary coccidioidomycosis \| coccidioidal lung granuloma \| Coccidioidal nodules \| Coccidioidal cavities \| Coccidioidal pyopneumothorax [CB2Z] Pleural, diaphragm or mediastinal disorders, unspecified Also known as: Pleural, diaphragm or mediastinal disorders, unspecified [DC51.1] Peritoneal adhesions Definition: Disorders of peritoneum sticking by scar tissue or fibrosis Also known as: Peritoneal adhesions \| abdominal adhesion \| adhesive peritoneal band \| peritoneal adhesion \| peritoneal band Excludes: Adhesions of large intestine with obstruction \| Postprocedural pelvic peritoneal adhesions \| Intestinal adhesions or bands of small intestine with obstruction === GRAPH WALKS === --- Walk 1 --- [MA82.2] Nasality Def: Nasality (or resonance) refers to the quality of the voice that is determined by the balance of sound vibration in the oral, nasal, and pharyngeal cavities during speech. Abnormal resonance can occur ... --PARENT--> [MA82] Voice disturbances Def: Voice disturbances include dysphonia, aphonia, hypernasality and hyponasality, and other voice disturbances.... --CHILD--> [MA82.0] Aphonia Def: Aphonia is the inability to produce voice. It is considered more severe than dysphonia. Like dysphonia, aphonia can be caused by voice strain or overuse, injury, by structural laryngeal anomalies or b... --- Walk 2 --- [MA82.2] Nasality Def: Nasality (or resonance) refers to the quality of the voice that is determined by the balance of sound vibration in the oral, nasal, and pharyngeal cavities during speech. Abnormal resonance can occur ... --PARENT--> [MA82] Voice disturbances Def: Voice disturbances include dysphonia, aphonia, hypernasality and hyponasality, and other voice disturbances.... --CHILD--> [MA82.2] Nasality Def: Nasality (or resonance) refers to the quality of the voice that is determined by the balance of sound vibration in the oral, nasal, and pharyngeal cavities during speech. Abnormal resonance can occur ... --- Walk 3 --- [CA0Z] Upper respiratory tract disorders, unspecified --PARENT--> [?] Upper respiratory tract disorders Def: This group of disorders refers to diseases of the upper airways (upper respiratory tract). The upper airways anatomically are complicated structures which extend from the airway openings at the nares ... --EXCLUDES--> [?] Chronic obstructive pulmonary disease with acute exacerbation, unspecified Def: An acute unspecified exacerbation of COPD is an acute event characterised by a worsening of the patient’s respiratory symptoms that is beyond normal day-to-day variations and leads to a change in medi... --- Walk 4 --- [CA0Z] Upper respiratory tract disorders, unspecified --PARENT--> [?] Upper respiratory tract disorders Def: This group of disorders refers to diseases of the upper airways (upper respiratory tract). The upper airways anatomically are complicated structures which extend from the airway openings at the nares ... --CHILD--> [CA01] Acute sinusitis Def: Recent onset and/or short duration inflammation of the mucosa in one or more of the paranasal sinuses (maxillary, ethmoid, frontal and sphenoid) arising from infection or other causes such as caries o... --- Walk 5 --- [CA0Y] Other specified upper respiratory tract disorders --PARENT--> [?] Upper respiratory tract disorders Def: This group of disorders refers to diseases of the upper airways (upper respiratory tract). The upper airways anatomically are complicated structures which extend from the airway openings at the nares ... --CHILD--> [CA01] Acute sinusitis Def: Recent onset and/or short duration inflammation of the mucosa in one or more of the paranasal sinuses (maxillary, ethmoid, frontal and sphenoid) arising from infection or other causes such as caries o... --- Walk 6 --- [CA0Y] Other specified upper respiratory tract disorders --PARENT--> [?] Upper respiratory tract disorders Def: This group of disorders refers to diseases of the upper airways (upper respiratory tract). The upper airways anatomically are complicated structures which extend from the airway openings at the nares ... --EXCLUDES--> [?] Chronic obstructive pulmonary disease with acute exacerbation, unspecified Def: An acute unspecified exacerbation of COPD is an acute event characterised by a worsening of the patient’s respiratory symptoms that is beyond normal day-to-day variations and leads to a change in medi...	[ "[MA82.2] Nasality\n Def: Nasality (or resonance) refers to the quality of the voice that is determined by the balance of sound vibration in the oral, nasal, and pharyngeal cavities during speech. Abnormal resonance can occur ...\n --PARENT--> [MA82] Voice disturbances\n Def: Voice disturbances include dysphonia, aphonia, hypernasality and hyponasality, and other voice disturbances....\n --CHILD--> [MA82.0] Aphonia\n Def: Aphonia is the inability to produce voice. It is considered more severe than dysphonia. Like dysphonia, aphonia can be caused by voice strain or overuse, injury, by structural laryngeal anomalies or b...", "[MA82.2] Nasality\n Def: Nasality (or resonance) refers to the quality of the voice that is determined by the balance of sound vibration in the oral, nasal, and pharyngeal cavities during speech. Abnormal resonance can occur ...\n --PARENT--> [MA82] Voice disturbances\n Def: Voice disturbances include dysphonia, aphonia, hypernasality and hyponasality, and other voice disturbances....\n --CHILD--> [MA82.2] Nasality\n Def: Nasality (or resonance) refers to the quality of the voice that is determined by the balance of sound vibration in the oral, nasal, and pharyngeal cavities during speech. Abnormal resonance can occur ...", "[CA0Z] Upper respiratory tract disorders, unspecified\n --PARENT--> [?] Upper respiratory tract disorders\n Def: This group of disorders refers to diseases of the upper airways (upper respiratory tract). The upper airways anatomically are complicated structures which extend from the airway openings at the nares ...\n --EXCLUDES--> [?] Chronic obstructive pulmonary disease with acute exacerbation, unspecified\n Def: An acute unspecified exacerbation of COPD is an acute event characterised by a worsening of the patient’s respiratory symptoms that is beyond normal day-to-day variations and leads to a change in medi...", "[CA0Z] Upper respiratory tract disorders, unspecified\n --PARENT--> [?] Upper respiratory tract disorders\n Def: This group of disorders refers to diseases of the upper airways (upper respiratory tract). The upper airways anatomically are complicated structures which extend from the airway openings at the nares ...\n --CHILD--> [CA01] Acute sinusitis\n Def: Recent onset and/or short duration inflammation of the mucosa in one or more of the paranasal sinuses (maxillary, ethmoid, frontal and sphenoid) arising from infection or other causes such as caries o...", "[CA0Y] Other specified upper respiratory tract disorders\n --PARENT--> [?] Upper respiratory tract disorders\n Def: This group of disorders refers to diseases of the upper airways (upper respiratory tract). The upper airways anatomically are complicated structures which extend from the airway openings at the nares ...\n --CHILD--> [CA01] Acute sinusitis\n Def: Recent onset and/or short duration inflammation of the mucosa in one or more of the paranasal sinuses (maxillary, ethmoid, frontal and sphenoid) arising from infection or other causes such as caries o...", "[CA0Y] Other specified upper respiratory tract disorders\n --PARENT--> [?] Upper respiratory tract disorders\n Def: This group of disorders refers to diseases of the upper airways (upper respiratory tract). The upper airways anatomically are complicated structures which extend from the airway openings at the nares ...\n --EXCLUDES--> [?] Chronic obstructive pulmonary disease with acute exacerbation, unspecified\n Def: An acute unspecified exacerbation of COPD is an acute event characterised by a worsening of the patient’s respiratory symptoms that is beyond normal day-to-day variations and leads to a change in medi..." ]	MA82.2	Nasality	[ { "from_icd11": "MA82.2", "icd10_code": "R4921", "icd10_title": "Hypernasality" }, { "from_icd11": "MA82.2", "icd10_code": "R4922", "icd10_title": "Hyponasality" }, { "from_icd11": "MA82.2", "icd10_code": "R492", "icd10_title": "Hypernasality and hyponasality" }, { "from_icd11": "CA0Z", "icd10_code": "J349", "icd10_title": "Unspecified disorder of nose and nasal sinuses" }, { "from_icd11": "CA0Z", "icd10_code": "J3489", "icd10_title": "Other specified disorders of nose and nasal sinuses" }, { "from_icd11": "CA0Z", "icd10_code": "J3481", "icd10_title": "Nasal mucositis (ulcerative)" }, { "from_icd11": "CA0Z", "icd10_code": "J398", "icd10_title": "Other specified diseases of upper respiratory tract" }, { "from_icd11": "CA0Z", "icd10_code": "J392", "icd10_title": "Other diseases of pharynx" }, { "from_icd11": "CA0Z", "icd10_code": "J399", "icd10_title": "Disease of upper respiratory tract, unspecified" }, { "from_icd11": "CA0Z", "icd10_code": "J00-J06", "icd10_title": "" }, { "from_icd11": "CA0Z", "icd10_code": "J30-J39", "icd10_title": "" }, { "from_icd11": "CA0Z", "icd10_code": "J34", "icd10_title": "Other and unspecified disorders of nose and nasal sinuses" }, { "from_icd11": "CA0Z", "icd10_code": "J348", "icd10_title": "Other specified disorders of nose and nasal sinuses" }, { "from_icd11": "CA0Z", "icd10_code": "J39", "icd10_title": "Other diseases of upper respiratory tract" }, { "from_icd11": "LA70.2", "icd10_code": "Q300", "icd10_title": "Choanal atresia" } ]	R4921	Hypernasality
Case 2 was a 63-year-old man, in reasonably good general health, affected by squamous cell carcinoma of the right commissure extending to upper and lower lips, stage T1N0M0 . The patient was treated with ablative surgery resulting in a defect involving the right commissure, 45% of the upper lip, to 25% of the lower lip, that was reconstructed with local flaps in the same surgical stage. The reconstruction was performed using the aforementioned association of two different flaps to restore both the cutaneous and vermillion structures of the lip by using a buccinator and an orbicularis sliding flap, respectively. A buccinator V-Y advancement muco-myo-cutaneous flap was used, modified by splitting the two bundles of the buccinator muscle, following the functional anatomy of the cheek-lip complex, where the fibers of the two bundles of the buccinator are connected to the two bundles of the upper and lower lip orbicularis oris muscle after modiolus insertion. In this way, the upper bundle was used to reconstruct the upper lip for the cutaneous area, and the lower beam was used to restore the lower lip skin area after resection. The modiolus was created by suturing the two buccinator bundles at the original position. The vermilion was reconstructed in association with this technique, combining two vermillion-orbicularis modified contralateral myo-mucosal flaps following the Goldstein–Robotti techniques .	4.015625	0.975098	sec[2]/p[5]	en	0.999998	PMC8870704	https://doi.org/10.3390/dj10020019	[ "buccinator", "bundles", "flaps", "cutaneous", "orbicularis", "used", "commissure", "stage", "reconstructed", "using" ]	[ { "code": "BC63.5", "title": "Nonspecific intraventricular conduction delay" }, { "code": "BC63.5&XK2J", "title": "Complete bundle branch block" }, { "code": "BC63.5&XK06", "title": "Incomplete bundle branch block" }, { "code": "BC63.4Z", "title": "Left bundle branch block, fascicle unspecified" }, { "code": "BC63.3", "title": "Right bundle branch block" }, { "code": "EM0Y", "title": "Other specified diseases of the skin" }, { "code": "EL51", "title": "Cutaneous flap necrosis" }, { "code": "EL52", "title": "Myocutaneous flap necrosis" }, { "code": "ME60.Z", "title": "Skin lesion of unspecified nature" }, { "code": "EB90.40", "title": "Dystrophic calcification of the skin of uncertain or unspecified aetiology" } ]	=== ICD-11 CODES FOUND === [BC63.5] Nonspecific intraventricular conduction delay Definition: Disorder of the atrioventricular conduction system characterised by a prolonged QRS duration (QRS duration greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and greater than 80 ms in children less than 8 years of age) without criteria for right or left bundle branch block. Also known as: Nonspecific intraventricular conduction delay \| intraventricular block NOS \| intraventricular block \| intraventricular conduction defect \| Bundle branch block [BC63.4Z] Left bundle branch block, fascicle unspecified Also known as: Left bundle branch block, fascicle unspecified \| Left bundle branch block \| Incomplete left bundle branch block [BC63.3] Right bundle branch block Definition: Disorder of the atrioventricular conduction system characterised by prolonged QRS duration (greater than or equal to 120 ms in adults, greater than 100 ms in children ages 4 to 16 years, and greater than 90 ms in children less than 4 years of age), rsr, rsR, or rSR in leads V1 or V2, S wave of greater duration than R wave (or greater than 40 ms in leads I and V6 in adults) Also known as: Right bundle branch block \| Complete right bundle branch block \| Incomplete right bundle branch block Includes: Incomplete right bundle branch block [EM0Y] Other specified diseases of the skin Also known as: Other specified diseases of the skin \| Adverse cutaneous effects of healthcare related interventions \| Cutaneous complications of surgical, laser or other interventional procedures \| Postprocedural cutaneous complications of surgical, laser or other interventions \| Cutaneous complications of surgical procedures [EL51] Cutaneous flap necrosis Definition: Necrosis of surgical skin flap Also known as: Cutaneous flap necrosis \| Cutaneous flap necrosis, partial \| Cutaneous flap necrosis, total [EL52] Myocutaneous flap necrosis Definition: Necrosis of a surgical flap containing both skin and muscle Also known as: Myocutaneous flap necrosis \| Myocutaneous flap necrosis, partial \| Myocutaneous flap necrosis, total [ME60.Z] Skin lesion of unspecified nature Also known as: Skin lesion of unspecified nature \| Skin lesion of uncertain or unspecified nature \| Skin lesion without established diagnosis \| Pigmented skin lesion of unspecified nature \| Ulcer of skin of unspecified nature [EB90.40] Dystrophic calcification of the skin of uncertain or unspecified aetiology Definition: Abnormal deposition of calcium in the skin and subcutaneous tissues of unknown (idiopathic) or unspecified cause. Also known as: Dystrophic calcification of the skin of uncertain or unspecified aetiology \| Calcinosis cutis of uncertain or unspecified aetiology \| Osteoma cutis \| Cutaneous ossification \| Subepidermal calcified nodule Includes: Calcinosis cutis === GRAPH WALKS === --- Walk 1 --- [BC63.5] Nonspecific intraventricular conduction delay Def: Disorder of the atrioventricular conduction system characterised by a prolonged QRS duration (QRS duration greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and great... --PARENT--> [BC63] Conduction disorders Def: Any abnormal alteration of atrio-ventricular conduction.... --PARENT--> [?] Cardiac arrhythmia Def: This is any of a large and heterogeneous group of conditions in which there is abnormal electrical activity in the heart. The heartbeat may be too fast or too slow, and may be regular or irregular.... --- Walk 2 --- [BC63.5] Nonspecific intraventricular conduction delay Def: Disorder of the atrioventricular conduction system characterised by a prolonged QRS duration (QRS duration greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and great... --PARENT--> [BC63] Conduction disorders Def: Any abnormal alteration of atrio-ventricular conduction.... --RELATED_TO--> [?] Congenital heart block Def: Heart block of any degree that is present at birth... --- Walk 3 --- [BC63.4Z] Left bundle branch block, fascicle unspecified --PARENT--> [BC63.4] Left bundle branch block Def: Disorder of the atrioventricular conduction system in which the QRS duration is greater than or equal to 120 ms in adults, greater than 100 ms in children 4 to 16 years of age, and greater than 90 ms ... --CHILD--> [BC63.41] Left posterior fascicular block Def: Disorder of the atrioventricular conduction system characterised by right axis deviation for age (between 90° and 180° in adults), with a qR pattern in inferior leads, rS pattern in leftward leads (I ... --- Walk 4 --- [BC63.4Z] Left bundle branch block, fascicle unspecified --PARENT--> [BC63.4] Left bundle branch block Def: Disorder of the atrioventricular conduction system in which the QRS duration is greater than or equal to 120 ms in adults, greater than 100 ms in children 4 to 16 years of age, and greater than 90 ms ... --CHILD--> [BC63.41] Left posterior fascicular block Def: Disorder of the atrioventricular conduction system characterised by right axis deviation for age (between 90° and 180° in adults), with a qR pattern in inferior leads, rS pattern in leftward leads (I ... --- Walk 5 --- [BC63.3] Right bundle branch block Def: Disorder of the atrioventricular conduction system characterised by prolonged QRS duration (greater than or equal to 120 ms in adults, greater than 100 ms in children ages 4 to 16 years, and greater t... --PARENT--> [BC63] Conduction disorders Def: Any abnormal alteration of atrio-ventricular conduction.... --RELATED_TO--> [?] Congenital heart block Def: Heart block of any degree that is present at birth... --- Walk 6 --- [BC63.3] Right bundle branch block Def: Disorder of the atrioventricular conduction system characterised by prolonged QRS duration (greater than or equal to 120 ms in adults, greater than 100 ms in children ages 4 to 16 years, and greater t... --PARENT--> [BC63] Conduction disorders Def: Any abnormal alteration of atrio-ventricular conduction.... --PARENT--> [?] Cardiac arrhythmia Def: This is any of a large and heterogeneous group of conditions in which there is abnormal electrical activity in the heart. The heartbeat may be too fast or too slow, and may be regular or irregular....	[ "[BC63.5] Nonspecific intraventricular conduction delay\n Def: Disorder of the atrioventricular conduction system characterised by a prolonged QRS duration (QRS duration greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and great...\n --PARENT--> [BC63] Conduction disorders\n Def: Any abnormal alteration of atrio-ventricular conduction....\n --PARENT--> [?] Cardiac arrhythmia\n Def: This is any of a large and heterogeneous group of conditions in which there is abnormal electrical activity in the heart. The heartbeat may be too fast or too slow, and may be regular or irregular....", "[BC63.5] Nonspecific intraventricular conduction delay\n Def: Disorder of the atrioventricular conduction system characterised by a prolonged QRS duration (QRS duration greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and great...\n --PARENT--> [BC63] Conduction disorders\n Def: Any abnormal alteration of atrio-ventricular conduction....\n --RELATED_TO--> [?] Congenital heart block\n Def: Heart block of any degree that is present at birth...", "[BC63.4Z] Left bundle branch block, fascicle unspecified\n --PARENT--> [BC63.4] Left bundle branch block\n Def: Disorder of the atrioventricular conduction system in which the QRS duration is greater than or equal to 120 ms in adults, greater than 100 ms in children 4 to 16 years of age, and greater than 90 ms ...\n --CHILD--> [BC63.41] Left posterior fascicular block\n Def: Disorder of the atrioventricular conduction system characterised by right axis deviation for age (between 90° and 180° in adults), with a qR pattern in inferior leads, rS pattern in leftward leads (I ...", "[BC63.4Z] Left bundle branch block, fascicle unspecified\n --PARENT--> [BC63.4] Left bundle branch block\n Def: Disorder of the atrioventricular conduction system in which the QRS duration is greater than or equal to 120 ms in adults, greater than 100 ms in children 4 to 16 years of age, and greater than 90 ms ...\n --CHILD--> [BC63.41] Left posterior fascicular block\n Def: Disorder of the atrioventricular conduction system characterised by right axis deviation for age (between 90° and 180° in adults), with a qR pattern in inferior leads, rS pattern in leftward leads (I ...", "[BC63.3] Right bundle branch block\n Def: Disorder of the atrioventricular conduction system characterised by prolonged QRS duration (greater than or equal to 120 ms in adults, greater than 100 ms in children ages 4 to 16 years, and greater t...\n --PARENT--> [BC63] Conduction disorders\n Def: Any abnormal alteration of atrio-ventricular conduction....\n --RELATED_TO--> [?] Congenital heart block\n Def: Heart block of any degree that is present at birth...", "[BC63.3] Right bundle branch block\n Def: Disorder of the atrioventricular conduction system characterised by prolonged QRS duration (greater than or equal to 120 ms in adults, greater than 100 ms in children ages 4 to 16 years, and greater t...\n --PARENT--> [BC63] Conduction disorders\n Def: Any abnormal alteration of atrio-ventricular conduction....\n --PARENT--> [?] Cardiac arrhythmia\n Def: This is any of a large and heterogeneous group of conditions in which there is abnormal electrical activity in the heart. The heartbeat may be too fast or too slow, and may be regular or irregular...." ]	BC63.5	Nonspecific intraventricular conduction delay	[ { "from_icd11": "BC63.5", "icd10_code": "I454", "icd10_title": "Nonspecific intraventricular block" }, { "from_icd11": "BC63.4Z", "icd10_code": "I447", "icd10_title": "Left bundle-branch block, unspecified" }, { "from_icd11": "BC63.4Z", "icd10_code": "I44", "icd10_title": "Atrioventricular and left bundle-branch block" }, { "from_icd11": "BC63.3", "icd10_code": "I4510", "icd10_title": "Unspecified right bundle-branch block" }, { "from_icd11": "BC63.3", "icd10_code": "I4519", "icd10_title": "Other right bundle-branch block" }, { "from_icd11": "BC63.3", "icd10_code": "I450", "icd10_title": "Right fascicular block" }, { "from_icd11": "BC63.3", "icd10_code": "I451", "icd10_title": "Other and unspecified right bundle-branch block" }, { "from_icd11": "EM0Y", "icd10_code": "L918", "icd10_title": "Other hypertrophic disorders of the skin" }, { "from_icd11": "EM0Y", "icd10_code": "L988", "icd10_title": "Other specified disorders of the skin and subcutaneous tissue" }, { "from_icd11": "EL51", "icd10_code": "T85898A", "icd10_title": "Other specified complication of other internal prosthetic devices, implants and grafts, initial encounter" }, { "from_icd11": "EL51", "icd10_code": "T8586XA", "icd10_title": "" }, { "from_icd11": "EL51", "icd10_code": "T85868A", "icd10_title": "Thrombosis due to other internal prosthetic devices, implants and grafts, initial encounter" }, { "from_icd11": "EL51", "icd10_code": "T85848A", "icd10_title": "Pain due to other internal prosthetic devices, implants and grafts, initial encounter" }, { "from_icd11": "EL51", "icd10_code": "T85858A", "icd10_title": "Stenosis due to other internal prosthetic devices, implants and grafts, initial encounter" }, { "from_icd11": "EL51", "icd10_code": "T85840A", "icd10_title": "Pain due to nervous system prosthetic devices, implants and grafts, initial encounter" } ]	I454	Nonspecific intraventricular block
Intravenous injection of recombinant tissue plasminogen activator (RT-PA) is an effective method for the treatment of acute ischemic stroke and can improve the survival rate and reduce the mortality rate of patients with acute ischemic stroke. However, in addition to intracranial hemorrhage, Orolingual angioedema (OA) is a rare but potentially life-threatening complication is increasing. OA presents as acute swelling of the tongue, lips, or face and can be life-threatening because it increases the risk of upper airway obstruction. However, the mechanisms underlying RT-PA-induced OA remain unclear. Increasing evidence suggests that RT-PA-induced OA is primarily driven by bradykinin and that close monitoring is important. Several studies have found that the use of angiotensin-converting enzyme (ACE) inhibitors is associated with an increased risk of angioedema following RT-PA. Some studies have also suggested that the female sex and insular infarction may be risk factors for OA. However, sex and infarct site were not found to be directly correlated. Herein, we report a case of a male patient with posterior circulation infarction who developed OA after intravenous thrombolysis (IVT). Previously, the patient had a rash on his chest after drinking alcohol, and he was usually administered enalapril to reduce blood pressure. Therefore, close observation during and after alteplase treatment is recommended.	4.207031	0.893066	sec[0]/p[0]	en	0.999997	36596071	https://doi.org/10.1097/MD.0000000000032474	[ "that", "however", "risk", "intravenous", "ischemic", "stroke", "reduce", "angioedema", "life", "threatening" ]	[ { "code": "8A80.Z", "title": "Migraine, unspecified" }, { "code": "QA76", "title": "Medication or substance that is known to be an allergen without injury or harm" }, { "code": "PL13.6", "title": "Medication or substance that is known to be an allergen, as mode of injury or harm" }, { "code": "9C40.A0", "title": "Papilloedema" }, { "code": "PA6Z", "title": "Unintentional fall from unspecified height" }, { "code": "QC4Y", "title": "Personal history of other specified health problems" }, { "code": "QA43.Z", "title": "Supervision of high-risk pregnancy, unspecified" }, { "code": "QA43.Y", "title": "Other specified supervision of high-risk pregnancy" }, { "code": "QD84.Z", "title": "Occupational exposure to risk-factors, unspecified" }, { "code": "MB26.A", "title": "Suicidal ideation" } ]	=== ICD-11 CODES FOUND === [8A80.Z] Migraine, unspecified Also known as: Migraine, unspecified \| Migraine [QA76] Medication or substance that is known to be an allergen without injury or harm Definition: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm. Also known as: Medication or substance that is known to be an allergen without injury or harm Excludes: Medication or substance that is known to be an allergen, as mode of injury or harm [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm Also known as: Medication or substance that is known to be an allergen, as mode of injury or harm \| medication error relating to known allergy to drug or substance \| adverse drug event relating to known allergy to drug or substance [9C40.A0] Papilloedema Definition: Optic disc swelling that results from increased intracranial pressure Also known as: Papilloedema \| Optic disc swelling that results from increased intracranial pressure Includes: Optic disc swelling that results from increased intracranial pressure [PA6Z] Unintentional fall from unspecified height Also known as: Unintentional fall from unspecified height \| fall NOS \| accidental fall \| fall causing injury that resulted in death \| fell NOS [QC4Y] Personal history of other specified health problems Also known as: Personal history of other specified health problems \| Personal history of diseases of the circulatory system \| history of disease or disorder of circulatory system \| personal history of conditions classifiable as diseases of the circulatory system \| Personal history of diseases of the respiratory system [QA43.Z] Supervision of high-risk pregnancy, unspecified Also known as: Supervision of high-risk pregnancy, unspecified \| Supervision of high-risk pregnancy [QA43.Y] Other specified supervision of high-risk pregnancy Also known as: Other specified supervision of high-risk pregnancy \| Supervision of pregnancy with grand multiparity \| pregnancy management affected by grand multiparity \| multiparity affecting management of pregnancy, labour and delivery \| pregnancy supervision for multiparity [QD84.Z] Occupational exposure to risk-factors, unspecified Also known as: Occupational exposure to risk-factors, unspecified \| Occupational exposure to risk-factors \| problem with occupational physical environment [MB26.A] Suicidal ideation Definition: Thoughts, ideas, or ruminations about the possibility of ending one's life, ranging from thinking that one would be better off dead to formulation of elaborate plans. Also known as: Suicidal ideation \| suicidal tendency \| suicidal tendencies \| suicidal ideation tendencies \| suicide risk Excludes: Suicide attempt \| Personal history of self-harm === GRAPH WALKS === --- Walk 1 --- [8A80.Z] Migraine, unspecified --PARENT--> [8A80] Migraine Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a... --CHILD--> [8A80.0] Migraine without aura Def: Recurrent headache disorder manifesting in attacks lasting 4-72 hours. The duration of attacks may be shorter in children. Typical characteristics of the headache are unilateral location, pulsating qu... --- Walk 2 --- [8A80.Z] Migraine, unspecified --PARENT--> [8A80] Migraine Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a... --CHILD--> [8A80.2] Chronic migraine Def: Headache occurring on 15 or more days per month for more than three months, which, on at least eight days per month, has the features of migraine headache and is not associated with medication overuse... --- Walk 3 --- [QA76] Medication or substance that is known to be an allergen without injury or harm Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm.... --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --- Walk 4 --- [QA76] Medication or substance that is known to be an allergen without injury or harm Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm.... --PARENT--> [?] Circumstances associated with exposure to a drug, medicament or biological substance influencing the episode of care without injury or harm --CHILD--> [QA70] Overdose of substance without injury or harm Def: Overdose of a substance occurs when a patient is given more of a prescribed drug or other substance than is intended. Can be the result of inaccurate measurement of drug, including oral administration... --- Walk 5 --- [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm Def: Incorrect dose - too high... --- Walk 6 --- [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --CHILD--> [PL13.1] Underdosing, as mode of injury or harm	[ "[8A80.Z] Migraine, unspecified\n --PARENT--> [8A80] Migraine\n Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a...\n --CHILD--> [8A80.0] Migraine without aura\n Def: Recurrent headache disorder manifesting in attacks lasting 4-72 hours. The duration of attacks may be shorter in children. Typical characteristics of the headache are unilateral location, pulsating qu...", "[8A80.Z] Migraine, unspecified\n --PARENT--> [8A80] Migraine\n Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a...\n --CHILD--> [8A80.2] Chronic migraine\n Def: Headache occurring on 15 or more days per month for more than three months, which, on at least eight days per month, has the features of migraine headache and is not associated with medication overuse...", "[QA76] Medication or substance that is known to be an allergen without injury or harm\n Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm....\n --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance", "[QA76] Medication or substance that is known to be an allergen without injury or harm\n Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm....\n --PARENT--> [?] Circumstances associated with exposure to a drug, medicament or biological substance influencing the episode of care without injury or harm\n --CHILD--> [QA70] Overdose of substance without injury or harm\n Def: Overdose of a substance occurs when a patient is given more of a prescribed drug or other substance than is intended. Can be the result of inaccurate measurement of drug, including oral administration...", "[PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance\n --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm\n Def: Incorrect dose - too high...", "[PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance\n --CHILD--> [PL13.1] Underdosing, as mode of injury or harm" ]	8A80.Z	Migraine, unspecified	[ { "from_icd11": "8A80.Z", "icd10_code": "G43B0", "icd10_title": "Ophthalmoplegic migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43409", "icd10_title": "Hemiplegic migraine, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A0", "icd10_title": "Cyclical vomiting, in migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D0", "icd10_title": "Abdominal migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43709", "icd10_title": "Chronic migraine without aura, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A1", "icd10_title": "Cyclical vomiting, in migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43509", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43719", "icd10_title": "Chronic migraine without aura, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43501", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C0", "icd10_title": "Periodic headache syndromes in child or adult, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43401", "icd10_title": "Hemiplegic migraine, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43419", "icd10_title": "Hemiplegic migraine, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43B1", "icd10_title": "Ophthalmoplegic migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C1", "icd10_title": "Periodic headache syndromes in child or adult, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D1", "icd10_title": "Abdominal migraine, intractable" } ]	G43B0	Ophthalmoplegic migraine, not intractable
A 63-year-old man with past medical history of AS diagnosed at 17 years of age, poorly controlled hypertension, and obesity was referred to the nephrology department for impaired kidney function with sCr of 1.6 mg/dL. Usual medication consisted in olmesartan, aliskiren, amlodipine, hydrochlorothiazide, fenofibrate, and allopurinol without recent changes or over-the-counter medications. Despite having controlled AS symptoms at the time of referral with no need for therapy, the patient had previous history of sulfasalazine and NSAIDs use. Aliskiren was suspended and carvedilol was initiated for better control of hypertension. Complementary studies revealed subnephrotic proteinuria (0.9g/24h), normal urinary sediment, and an erythrocyte sedimentation rate (ESR) of 56 mm/h. Immunologic studies and serum electrophoresis were unremarkable as were hepatitis B (HBV), C (HCV), and human immunodeficiency (HIV) virus serologies. For the next 6 months, the patient evolved with progressive kidney impairment reaching a sCr of 3 mg/dL. Kidney biopsy was performed and revealed 90% of interstitial fibrosis with tubular atrophy and an area of inflammatory infiltrate, consistent with CIN . As other etiologies were excluded, CIN was attributed to chronic analgesic abuse and/or previous use of sulfasalazine. The patient progressed to kidney failure and eventually started peritoneal dialysis 2 years after the diagnosis.	3.935547	0.981934	sec[2]/sec[1]/sec[0]/p[0]	en	0.999994	35579342	https://doi.org/10.1590/2175-8239-JBN-2022-0008	[ "kidney", "controlled", "hypertension", "aliskiren", "sulfasalazine", "past", "diagnosed", "poorly", "obesity", "referred" ]	[ { "code": "GC2Z&XA6KU8", "title": "Disease of kidney, not elsewhere classified" }, { "code": "GB6Z", "title": "Kidney failure, unspecified" }, { "code": "LB30.1", "title": "Renal dysplasia" }, { "code": "NB92.0Y", "title": "Other specified injury of kidney" }, { "code": "LB30.7", "title": "Ectopic or pelvic kidney" }, { "code": "6C01.Z", "title": "Encopresis, unspecified" }, { "code": "6C00.Z", "title": "Enuresis, unspecified" }, { "code": "MF50.2Z", "title": "Urinary incontinence, unspecified" }, { "code": "5A14", "title": "Diabetes mellitus, type unspecified" }, { "code": "6C0Z", "title": "Elimination disorders, unspecified" } ]	=== ICD-11 CODES FOUND === [GB6Z] Kidney failure, unspecified Also known as: Kidney failure, unspecified \| nontraumatic kidney injury \| renal failure NOS \| kidney block \| renal impairment NOS [LB30.1] Renal dysplasia Definition: A condition characterised by abnormal development of one or both kidneys. Also known as: Renal dysplasia \| congenital renal dysplasia \| dysplasia of kidney \| dysplastic kidney \| Primary renal dysplasia Excludes: Autosomal dominant polycystic kidney disease [NB92.0Y] Other specified injury of kidney Also known as: Other specified injury of kidney \| Injury of kidney without open wound into cavity \| Injury of kidney with open wound into cavity \| Haematoma of kidney \| traumatic perirenal haematoma [LB30.7] Ectopic or pelvic kidney Definition: A birth defect characterised by an abnormally positioned kidney; may be asymptomatic or result in urine blockage, infection or kidney stones Also known as: Ectopic or pelvic kidney \| Congenital displaced kidney \| congenital misplaced kidney \| congenital malposition of kidney \| congenital prolapsed kidney Includes: Congenital displaced kidney \| Malrotation of kidney [6C01.Z] Encopresis, unspecified Also known as: Encopresis, unspecified \| Encopresis \| Problems of bowel control \| encopresis of nonorganic origin \| faecal incontinence of nonorganic origin [6C00.Z] Enuresis, unspecified Also known as: Enuresis, unspecified \| Enuresis \| Functional enuresis \| Problems of bladder control \| enuresis NOS [MF50.2Z] Urinary incontinence, unspecified Also known as: Urinary incontinence, unspecified \| Urinary incontinence \| urinary incontinence, NOS \| bladder incontinence NOS \| absence of bladder continence [5A14] Diabetes mellitus, type unspecified Also known as: Diabetes mellitus, type unspecified \| diabetes NOS \| DM - [diabetes mellitus] NOS \| severe diabetes mellitus \| sudden-onset diabetes mellitus Excludes: Idiopathic Type 1 diabetes mellitus \| Type 2 diabetes mellitus \| Diabetes mellitus, other specified type [6C0Z] Elimination disorders, unspecified Also known as: Elimination disorders, unspecified \| Problems of bowel or bladder control === GRAPH WALKS === --- Walk 1 --- [GB6Z] Kidney failure, unspecified --PARENT--> [?] Kidney failure Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ... --RELATED_TO--> [?] Congenital renal failure Def: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate urine, and maintain electrolyte balance; blood pressure; and calcium metabolism which existed at, or often before,... --- Walk 2 --- [GB6Z] Kidney failure, unspecified --PARENT--> [?] Kidney failure Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ... --CHILD--> [GB61] Chronic kidney disease Def: Glomerular Filtration Rate (GFR) < 60 ml/min/1.73m² or presence of kidney damage that is present for more than 3 months. Evidence of kidney damage can include structural abnormalities (imaging or hist... --- Walk 3 --- [LB30.1] Renal dysplasia Def: A condition characterised by abnormal development of one or both kidneys.... --EXCLUDES--> [?] Autosomal dominant polycystic kidney disease Def: Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and d... --PARENT--> [?] Hereditary cystic or dysplastic kidney disease, dominant inheritance Def: Cystic or dysplastic renal diseases that are inherited in an autosomal dominant fashion. Usually monogenetic, and can be associated with abnormalities in other organs.... --- Walk 4 --- [LB30.1] Renal dysplasia Def: A condition characterised by abnormal development of one or both kidneys.... --PARENT--> [LB30] Structural developmental anomalies of kidneys Def: Any condition caused by failure of the kidneys to correctly develop during the antenatal period.... --CHILD--> [LB30.1] Renal dysplasia Def: A condition characterised by abnormal development of one or both kidneys.... --- Walk 5 --- [NB92.0Y] Other specified injury of kidney --PARENT--> [NB92.0] Injury of kidney --CHILD--> [NB92.00] Contusion of kidney, minor --- Walk 6 --- [NB92.0Y] Other specified injury of kidney --PARENT--> [NB92.0] Injury of kidney --CHILD--> [NB92.02] Laceration of kidney, minor	[ "[GB6Z] Kidney failure, unspecified\n --PARENT--> [?] Kidney failure\n Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ...\n --RELATED_TO--> [?] Congenital renal failure\n Def: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate urine, and maintain electrolyte balance; blood pressure; and calcium metabolism which existed at, or often before,...", "[GB6Z] Kidney failure, unspecified\n --PARENT--> [?] Kidney failure\n Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ...\n --CHILD--> [GB61] Chronic kidney disease\n Def: Glomerular Filtration Rate (GFR) < 60 ml/min/1.73m² or presence of kidney damage that is present for more than 3 months. Evidence of kidney damage can include structural abnormalities (imaging or hist...", "[LB30.1] Renal dysplasia\n Def: A condition characterised by abnormal development of one or both kidneys....\n --EXCLUDES--> [?] Autosomal dominant polycystic kidney disease\n Def: Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and d...\n --PARENT--> [?] Hereditary cystic or dysplastic kidney disease, dominant inheritance\n Def: Cystic or dysplastic renal diseases that are inherited in an autosomal dominant fashion. Usually monogenetic, and can be associated with abnormalities in other organs....", "[LB30.1] Renal dysplasia\n Def: A condition characterised by abnormal development of one or both kidneys....\n --PARENT--> [LB30] Structural developmental anomalies of kidneys\n Def: Any condition caused by failure of the kidneys to correctly develop during the antenatal period....\n --CHILD--> [LB30.1] Renal dysplasia\n Def: A condition characterised by abnormal development of one or both kidneys....", "[NB92.0Y] Other specified injury of kidney\n --PARENT--> [NB92.0] Injury of kidney\n --CHILD--> [NB92.00] Contusion of kidney, minor", "[NB92.0Y] Other specified injury of kidney\n --PARENT--> [NB92.0] Injury of kidney\n --CHILD--> [NB92.02] Laceration of kidney, minor" ]	GC2Z&XA6KU8	Disease of kidney, not elsewhere classified	[ { "from_icd11": "GB6Z", "icd10_code": "N19", "icd10_title": "Unspecified kidney failure" }, { "from_icd11": "GB6Z", "icd10_code": "N17-N19", "icd10_title": "" }, { "from_icd11": "GB6Z", "icd10_code": "N17", "icd10_title": "Acute kidney failure" }, { "from_icd11": "LB30.1", "icd10_code": "Q614", "icd10_title": "Renal dysplasia" }, { "from_icd11": "LB30.7", "icd10_code": "Q632", "icd10_title": "Ectopic kidney" }, { "from_icd11": "LB30.7", "icd10_code": "Q63", "icd10_title": "Other congenital malformations of kidney" }, { "from_icd11": "6C01.Z", "icd10_code": "F981", "icd10_title": "Encopresis not due to a substance or known physiological condition" }, { "from_icd11": "6C00.Z", "icd10_code": "F980", "icd10_title": "Enuresis not due to a substance or known physiological condition" }, { "from_icd11": "MF50.2Z", "icd10_code": "N39498", "icd10_title": "Other specified urinary incontinence" }, { "from_icd11": "MF50.2Z", "icd10_code": "N3941", "icd10_title": "Urge incontinence" }, { "from_icd11": "MF50.2Z", "icd10_code": "N3946", "icd10_title": "Mixed incontinence" }, { "from_icd11": "MF50.2Z", "icd10_code": "N3945", "icd10_title": "Continuous leakage" }, { "from_icd11": "MF50.2Z", "icd10_code": "N3944", "icd10_title": "Nocturnal enuresis" }, { "from_icd11": "MF50.2Z", "icd10_code": "N39490", "icd10_title": "Overflow incontinence" }, { "from_icd11": "MF50.2Z", "icd10_code": "N3943", "icd10_title": "Post-void dribbling" } ]	N19	Unspecified kidney failure
In an 83-year-old male former smoker (30 pack-years) with multiple comorbidities but with a good performance status (ECOG 1), the work-up of a symptomatic left pleural effusion led to the detection of a lung lesion in the left lower lobe accompanied by lymphangiosis, as well as discrete hilar and mediastinal lymphadenopathy. Drainage of the pleural effusion revealed single cells of a thyroid transcription factor 1 (TTF-1)-positive pulmonary adenocarcinoma. Further molecular analysis was not possible due to the scarcity of tumour cells in the cyto spin. For further classification of the non-squamous NSCLC, cytological material was obtained by EBUS-EBNA from mediastinal lymph nodes (LN) in position 4L, the best accessible site according to the staging CT . Despite representative material according to rapid on-site evaluation of four TBNAs (each with 8–10 needle passes), no malignant cells were evident in the LN aspirate. A subsequent CT guided transthoracic biopsy again yielded too few tumour cells for DNA and RNA extraction for next generation sequencing (NGS). Due to the cardiovascular comorbidities in our patient, the perioperative risk of mediastinoscopy was considered to be increased, albeit low overall, and the patient refused the intervention. Liquid biopsy was deemed unlikely to help in the detection or exclusion of actionable molecular alterations due to the overall low systemic tumour load.	4.117188	0.961426	sec[1]/p[0]	en	0.999998	36983354	https://doi.org/10.3390/jcm12062355	[ "cells", "tumour", "comorbidities", "pleural", "effusion", "detection", "mediastinal", "molecular", "material", "site" ]	[ { "code": "MF9Y", "title": "Other specified clinical findings on examination of urine, without diagnosis" }, { "code": "5C56.20", "title": "Mucolipidosis" }, { "code": "3A51.1", "title": "Sickle cell disease without crisis" }, { "code": "9A96.3", "title": "Primary anterior uveitis" }, { "code": "3A61.Z", "title": "Acquired pure red cell aplasia, unspecified" }, { "code": "2F9Z", "title": "Neoplasms of unknown behaviour of unspecified site" }, { "code": "ME61", "title": "Subcutaneous swelling, mass or lump of uncertain or unspecified nature" }, { "code": "2E6Z", "title": "Carcinoma in situ of unspecified site" }, { "code": "2F91.1", "title": "Neoplasms of unknown behaviour of trachea, bronchus or lung" }, { "code": "2F92", "title": "Neoplasms of unknown behaviour of skin" } ]	=== ICD-11 CODES FOUND === [MF9Y] Other specified clinical findings on examination of urine, without diagnosis Also known as: Other specified clinical findings on examination of urine, without diagnosis \| Methaemoglobinuria \| Other and unspecified abnormal findings in urine \| Calciuria \| Cells and casts in urine [5C56.20] Mucolipidosis Also known as: Mucolipidosis \| Mucolipidosis type 3 \| Pseudo-Hurler polydystrophy \| Pseudo-Hurler disease \| Mucolipidosis type 2 Excludes: Sialidosis (mucolipidosis type 1) [3A51.1] Sickle cell disease without crisis Definition: A disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may present with fatigue, shortness of breath, dizziness, headaches, pallor of skin or mucous membranes, and jaundice. This disorder is confirmed by identification of HbS mutation by genetic testing. Also known as: Sickle cell disease without crisis \| Hb-SS disease without crisis \| HbSS without crisis \| Sickle-cell anaemia without crisis \| SCD - [sickle cell disease] [9A96.3] Primary anterior uveitis Definition: This refers to primary inflammation of the uvea. The uvea consists of the middle, pigmented, vascular structures of the eye and includes the iris, ciliary body, and choroid. Also known as: Primary anterior uveitis \| anterior chamber cell [3A61.Z] Acquired pure red cell aplasia, unspecified Also known as: Acquired pure red cell aplasia, unspecified \| Acquired pure red cell aplasia \| acquired red cell aplasia \| red cell aplasia NOS \| pure red cell aplastic anaemia [2F9Z] Neoplasms of unknown behaviour of unspecified site Also known as: Neoplasms of unknown behaviour of unspecified site \| neoplasia \| neoplasm growth NOS \| tumour of unspecified site \| tumourlet of unspecified site [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Definition: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature Also known as: Subcutaneous swelling, mass or lump of uncertain or unspecified nature \| localised swelling, mass or lump of skin and subcutaneous tissue \| localised subcutaneous nodules \| subcutaneous nodules \| superficial subcutaneous nodules Excludes: localized adiposity \| mass and lump: breast \| enlarged lymph nodes [2E6Z] Carcinoma in situ of unspecified site Also known as: Carcinoma in situ of unspecified site \| carcinoma in situ of unspecified site \| carcinoma in situ NOS \| carcinoma in situ \| in situ neoplasm [2F91.1] Neoplasms of unknown behaviour of trachea, bronchus or lung Also known as: Neoplasms of unknown behaviour of trachea, bronchus or lung \| trachea, bronchus or lung tumour NOS \| Intravascular bronchial alveolar tumour of unspecified site \| Bronchial adenoma of unknown behaviour of unspecified site \| Intravascular bronchial alveolar tumour unknown behaviour of unspecified site [2F92] Neoplasms of unknown behaviour of skin Also known as: Neoplasms of unknown behaviour of skin \| skin tumour NOS === GRAPH WALKS === --- Walk 1 --- [MF9Y] Other specified clinical findings on examination of urine, without diagnosis --PARENT--> [?] Clinical findings on examination of urine, without diagnosis --EXCLUDES--> [?] Inborn errors of carbohydrate metabolism --- Walk 2 --- [MF9Y] Other specified clinical findings on examination of urine, without diagnosis --PARENT--> [?] Clinical findings on examination of urine, without diagnosis --EXCLUDES--> [?] Clinical findings on antenatal screening of mother Def: Any sign characterised by an abnormality detected during an antenatal screening of the mother.... --- Walk 3 --- [5C56.20] Mucolipidosis --RELATED_TO--> [?] Wolman disease Def: Wolman disease represents the most severe manifestation of lysosomal acid lipase deficiency and can present in the fetus (hepatomegaly, ascites, calcified adrenal glands), or more typically in the fir... --PARENT--> [?] Lysosomal acid lipase deficiency Def: Lysosomal Acid Lipase (LAL) Deficiency happens when the body does not produce enough active lysosomal acid lipase (LAL or LIPA) enzyme. This enzyme plays an important role in breaking down fatty mater... --- Walk 4 --- [5C56.20] Mucolipidosis --PARENT--> [5C56.2] Glycoproteinosis Def: These are lysosomal storage diseases affecting glycoproteins, resulting from defects in lysosomal function. The term is sometimes reserved for conditions involving degradation of glycoproteins.... --CHILD--> [5C56.2Y] Other specified glycoproteinosis --- Walk 5 --- [3A51.1] Sickle cell disease without crisis Def: A disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may pr... --PARENT--> [3A51] Sickle cell disorders or other haemoglobinopathies Def: Any disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may ... --CHILD--> [3A51.0] Sickle cell trait Def: A disease caused by genetic inheritance of one abnormal allele of the haemoglobin gene. This disease does not display the severe symptoms of sickle cell disease that occurs in homozygous individuals. ... --- Walk 6 --- [3A51.1] Sickle cell disease without crisis Def: A disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may pr... --PARENT--> [3A51] Sickle cell disorders or other haemoglobinopathies Def: Any disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may ... --RELATED_TO--> [?] Other sickle-cell disorders with retinopathy Def: This is an autosomal recessive genetic blood disorder with overdominance, characterised by red blood cells that assume an abnormal, rigid, sickle shape. This diagnosis is due to persistent or acute da...	[ "[MF9Y] Other specified clinical findings on examination of urine, without diagnosis\n --PARENT--> [?] Clinical findings on examination of urine, without diagnosis\n --EXCLUDES--> [?] Inborn errors of carbohydrate metabolism", "[MF9Y] Other specified clinical findings on examination of urine, without diagnosis\n --PARENT--> [?] Clinical findings on examination of urine, without diagnosis\n --EXCLUDES--> [?] Clinical findings on antenatal screening of mother\n Def: Any sign characterised by an abnormality detected during an antenatal screening of the mother....", "[5C56.20] Mucolipidosis\n --RELATED_TO--> [?] Wolman disease\n Def: Wolman disease represents the most severe manifestation of lysosomal acid lipase deficiency and can present in the fetus (hepatomegaly, ascites, calcified adrenal glands), or more typically in the fir...\n --PARENT--> [?] Lysosomal acid lipase deficiency\n Def: Lysosomal Acid Lipase (LAL) Deficiency happens when the body does not produce enough active lysosomal acid lipase (LAL or LIPA) enzyme. This enzyme plays an important role in breaking down fatty mater...", "[5C56.20] Mucolipidosis\n --PARENT--> [5C56.2] Glycoproteinosis\n Def: These are lysosomal storage diseases affecting glycoproteins, resulting from defects in lysosomal function. The term is sometimes reserved for conditions involving degradation of glycoproteins....\n --CHILD--> [5C56.2Y] Other specified glycoproteinosis", "[3A51.1] Sickle cell disease without crisis\n Def: A disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may pr...\n --PARENT--> [3A51] Sickle cell disorders or other haemoglobinopathies\n Def: Any disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may ...\n --CHILD--> [3A51.0] Sickle cell trait\n Def: A disease caused by genetic inheritance of one abnormal allele of the haemoglobin gene. This disease does not display the severe symptoms of sickle cell disease that occurs in homozygous individuals. ...", "[3A51.1] Sickle cell disease without crisis\n Def: A disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may pr...\n --PARENT--> [3A51] Sickle cell disorders or other haemoglobinopathies\n Def: Any disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may ...\n --RELATED_TO--> [?] Other sickle-cell disorders with retinopathy\n Def: This is an autosomal recessive genetic blood disorder with overdominance, characterised by red blood cells that assume an abnormal, rigid, sickle shape. This diagnosis is due to persistent or acute da..." ]	MF9Y	Other specified clinical findings on examination of urine, without diagnosis	[ { "from_icd11": "3A51.1", "icd10_code": "D571", "icd10_title": "Sickle-cell disease without crisis" }, { "from_icd11": "3A61.Z", "icd10_code": "D609", "icd10_title": "Acquired pure red cell aplasia, unspecified" }, { "from_icd11": "3A61.Z", "icd10_code": "D608", "icd10_title": "Other acquired pure red cell aplasias" }, { "from_icd11": "3A61.Z", "icd10_code": "D60", "icd10_title": "Acquired pure red cell aplasia [erythroblastopenia]" }, { "from_icd11": "2F9Z", "icd10_code": "D487", "icd10_title": "Neoplasm of uncertain behavior of other specified sites" }, { "from_icd11": "2F9Z", "icd10_code": "D482", "icd10_title": "Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system" }, { "from_icd11": "2F9Z", "icd10_code": "D37-D48", "icd10_title": "" }, { "from_icd11": "2F9Z", "icd10_code": "D377", "icd10_title": "" }, { "from_icd11": "2F9Z", "icd10_code": "D48", "icd10_title": "Neoplasm of uncertain behavior of other and unspecified sites" }, { "from_icd11": "2F9Z", "icd10_code": "D489", "icd10_title": "Neoplasm of uncertain behavior, unspecified" }, { "from_icd11": "ME61", "icd10_code": "R2240", "icd10_title": "Localized swelling, mass and lump, unspecified lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2232", "icd10_title": "Localized swelling, mass and lump, left upper limb" }, { "from_icd11": "ME61", "icd10_code": "R2242", "icd10_title": "Localized swelling, mass and lump, left lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2231", "icd10_title": "Localized swelling, mass and lump, right upper limb" }, { "from_icd11": "ME61", "icd10_code": "R2241", "icd10_title": "Localized swelling, mass and lump, right lower limb" } ]	D571	Sickle-cell disease without crisis
The patient then partially aligns with the doctor, saying that it “maybe” is the case that he is too stressed, but then says he “knows his body” (l9), using “but” to contrast this initial partial alignment. He accounts for this different assessment, including a number of longer pauses, further signalling potential misalignment and interactional delicacy. His account is built around his experiential knowledge of his illness, which acts as a resource to overrule the assessment of the medical team. Interestingly, his assessment as such is dualistic, but at the same time, he refers to stress as something bodily. More specifically, he explains his high levels of stress as a problem that his dad has too, with which he seems to suggest he either genetically inherited from his father, or that it is the result of his upbringing (l9-10). In doing so, he implies that his stress and urinary problems are unrelated, as the stress has been an issue for much longer than the urinary problems. Moreover, he also appeals to the hierarchy associated with mind-body dualism, more specifically with the evaluative component that psychological problems are usually considered more intentional, and therefore also more problematic. By constructing his stress as familial, he constructs it as an issue that is unintentional and beyond his control, and consequently, he creates another resources to overturn the doctor’s assessment.	3.316406	0.556641	sec[3]/sec[1]/p[6]	en	0.999998	34291691	https://doi.org/10.1177/13634593211032875	[ "that", "stress", "problems", "doctor", "body", "this", "longer", "which", "specifically", "urinary" ]	[ { "code": "8A80.Z", "title": "Migraine, unspecified" }, { "code": "QA76", "title": "Medication or substance that is known to be an allergen without injury or harm" }, { "code": "PL13.6", "title": "Medication or substance that is known to be an allergen, as mode of injury or harm" }, { "code": "9C40.A0", "title": "Papilloedema" }, { "code": "PA6Z", "title": "Unintentional fall from unspecified height" }, { "code": "QE01", "title": "Stress, not elsewhere classified" }, { "code": "QE84", "title": "Acute stress reaction" }, { "code": "6B4Z", "title": "Disorders specifically associated with stress, unspecified" }, { "code": "3B61.1", "title": "Acquired thrombophilia" }, { "code": "DA60.3", "title": "Stress ulcer of stomach" } ]	=== ICD-11 CODES FOUND === [8A80.Z] Migraine, unspecified Also known as: Migraine, unspecified \| Migraine [QA76] Medication or substance that is known to be an allergen without injury or harm Definition: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm. Also known as: Medication or substance that is known to be an allergen without injury or harm Excludes: Medication or substance that is known to be an allergen, as mode of injury or harm [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm Also known as: Medication or substance that is known to be an allergen, as mode of injury or harm \| medication error relating to known allergy to drug or substance \| adverse drug event relating to known allergy to drug or substance [9C40.A0] Papilloedema Definition: Optic disc swelling that results from increased intracranial pressure Also known as: Papilloedema \| Optic disc swelling that results from increased intracranial pressure Includes: Optic disc swelling that results from increased intracranial pressure [PA6Z] Unintentional fall from unspecified height Also known as: Unintentional fall from unspecified height \| fall NOS \| accidental fall \| fall causing injury that resulted in death \| fell NOS [QE01] Stress, not elsewhere classified Also known as: Stress, not elsewhere classified \| stress NOS \| Physical or mental strain not elsewhere classified Excludes: Problems associated with employment or unemployment [QE84] Acute stress reaction Definition: Acute stress reaction refers to the development of transient emotional, somatic, cognitive, or behavioural symptoms as a result of exposure to an event or situation (either short- or long-lasting) of an extremely threatening or horrific nature (e.g., natural or human-made disasters, combat, serious accidents, sexual violence, assault). Symptoms may include autonomic signs of anxiety (e.g., tachycardia, sweating, flushing), being in a daze, confusion, sadness, anxiety, anger, despair, overactivit Also known as: Acute stress reaction \| acute stress disorder \| acute crisis reaction \| acute reaction to stress \| psychic shock Includes: acute crisis reaction \| acute reaction to stress Excludes: Post traumatic stress disorder [6B4Z] Disorders specifically associated with stress, unspecified Also known as: Disorders specifically associated with stress, unspecified \| reaction to severe stress, and adjustment disorders \| Trauma- and stressor-related disorders \| stressor-related disorders \| stress-related disorders [3B61.1] Acquired thrombophilia Definition: A disease caused by determinants arising after birth. This disease is characterised by abnormality of blood coagulation that increases the risk of thrombosis, clots in blood vessels. This disease may present with deep vein thrombosis or pulmonary embolism. Confirmation is identification of abnormal blood coagulation in a blood sample. Also known as: Acquired thrombophilia \| Gaisbock syndrome \| polycythaemia due to stress \| stress erythrocytosis \| stress polycythaemia [DA60.3] Stress ulcer of stomach Definition: Stress ulcers of stomach are acute mucosal lesions occurring in critically ill patients that may result in acute upper gastrointestinal bleeding. They are usually superficial erosions but can develop into ulcers. Stress ulcers of stomach may develop anywhere within the stomach but are more likely to occur in fundic mucosa, which lines the body and fundus of the stomach. Also known as: Stress ulcer of stomach \| Acute curlings ulcer \| acute eroded curlings ulcer \| Acute perforated curlings ulcer \| Acute gastric stress ulcer === GRAPH WALKS === --- Walk 1 --- [8A80.Z] Migraine, unspecified --PARENT--> [8A80] Migraine Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a... --CHILD--> [8A80.1] Migraine with aura Def: Recurrent attacks, lasting minutes, of unilateral fully-reversible visual, sensory or other central nervous system symptoms that usually develop gradually and are usually followed by headache and asso... --- Walk 2 --- [8A80.Z] Migraine, unspecified --PARENT--> [8A80] Migraine Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a... --PARENT--> [?] Headache disorders --- Walk 3 --- [QA76] Medication or substance that is known to be an allergen without injury or harm Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm.... --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --- Walk 4 --- [QA76] Medication or substance that is known to be an allergen without injury or harm Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm.... --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --- Walk 5 --- [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm Def: Incorrect dose - too high... --- Walk 6 --- [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm Def: Incorrect dose - too high...	[ "[8A80.Z] Migraine, unspecified\n --PARENT--> [8A80] Migraine\n Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a...\n --CHILD--> [8A80.1] Migraine with aura\n Def: Recurrent attacks, lasting minutes, of unilateral fully-reversible visual, sensory or other central nervous system symptoms that usually develop gradually and are usually followed by headache and asso...", "[8A80.Z] Migraine, unspecified\n --PARENT--> [8A80] Migraine\n Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a...\n --PARENT--> [?] Headache disorders", "[QA76] Medication or substance that is known to be an allergen without injury or harm\n Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm....\n --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance", "[QA76] Medication or substance that is known to be an allergen without injury or harm\n Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm....\n --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance", "[PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance\n --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm\n Def: Incorrect dose - too high...", "[PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance\n --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm\n Def: Incorrect dose - too high..." ]	8A80.Z	Migraine, unspecified	[ { "from_icd11": "8A80.Z", "icd10_code": "G43B0", "icd10_title": "Ophthalmoplegic migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43409", "icd10_title": "Hemiplegic migraine, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A0", "icd10_title": "Cyclical vomiting, in migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D0", "icd10_title": "Abdominal migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43709", "icd10_title": "Chronic migraine without aura, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A1", "icd10_title": "Cyclical vomiting, in migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43509", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43719", "icd10_title": "Chronic migraine without aura, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43501", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C0", "icd10_title": "Periodic headache syndromes in child or adult, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43401", "icd10_title": "Hemiplegic migraine, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43419", "icd10_title": "Hemiplegic migraine, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43B1", "icd10_title": "Ophthalmoplegic migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C1", "icd10_title": "Periodic headache syndromes in child or adult, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D1", "icd10_title": "Abdominal migraine, intractable" } ]	G43B0	Ophthalmoplegic migraine, not intractable
Our patient suffered from recurrent attacks of nocturnal hypoglycemia. Pathological conditions such as insulinoma were ruled out. Such episodes are not routinely described in PBH. Explaining patterns of nocturnal hypoglycemia in post-bariatric patients is the scope of future studies. As nocturnal episodes are detrimental to health by impacting cardiovascular function and affecting neuronal and cognitive function, there is a need to further enhance the literature on PBH. Our patient responded to nifedipine and acarbose, and the episodes of hypoglycemia had completely resolved before discharge. There is multidisciplinary team involvement in managing the case. One end of the spectrum lies in preventing such episodes in the first place with dietary modification and strict glucose monitoring. For those refractory to dietary modifications, the addition of medical therapy is advised. If, despite all measures, the patient still continues to have uncontrolled or severe, refractory episodes of PBH, then surgical management is advocated. At times, hypoglycemic episodes go unnoticed, and patients are unaware of hypoglycemia. Continuous glucose monitoring using the CGMS machine can mitigate this issue, helping to prevent the development of neuroglycopenic episodes and further worsening. In our patient's case, at follow-up, the patient was doing well with dietary modifications as well as acarbose and nifedipine.	4.019531	0.961914	sec[2]/p[8]	en	0.999998	PMC10292178	https://doi.org/10.7759/cureus.39544	[ "episodes", "hypoglycemia", "nocturnal", "dietary", "patients", "function", "nifedipine", "acarbose", "glucose", "monitoring" ]	[ { "code": "8A68.Y", "title": "Other specified type of seizure" }, { "code": "MD11.1", "title": "Asphyxia" }, { "code": "AB31.Z", "title": "Episodic vestibular syndrome, unspecified" }, { "code": "AB31.Y", "title": "Other specified episodic vestibular syndrome" }, { "code": "6C45.0", "title": "Episode of harmful use of cocaine" }, { "code": "5A41", "title": "Hypoglycaemia without associated diabetes" }, { "code": "5A4Z", "title": "Disorders of glucose regulation or pancreatic internal secretion, unspecified" }, { "code": "5A45", "title": "Persistent hyperinsulinaemic hypoglycaemia of infancy" }, { "code": "KB60.4Z", "title": "Neonatal hypoglycaemia, unspecified" }, { "code": "8D8D", "title": "Hypoglycaemia unawareness" } ]	=== ICD-11 CODES FOUND === [8A68.Y] Other specified type of seizure Also known as: Other specified type of seizure \| Absence episode \| Absence seizure episode \| Pseudotetanus \| Clonic seizure disorder [MD11.1] Asphyxia Definition: Asphyxia is a life-threatening condition in which oxygen is prevented from reaching the tissues by obstruction of or damage to any part of the respiratory system. More generally the term indicates all the conditions generating impaired or impeded breathing. Also known as: Asphyxia \| pathological asphyxia \| decreased oxygen supply \| oxygen deficiency \| positional asphyxia Excludes: asphyxia due to foreign body in respiratory tract \| asphyxia due to carbon monoxide \| asphyxia due to traumatic [AB31.Z] Episodic vestibular syndrome, unspecified Also known as: Episodic vestibular syndrome, unspecified \| Episodic vestibular syndrome [AB31.Y] Other specified episodic vestibular syndrome Also known as: Other specified episodic vestibular syndrome \| Secondary episodic vestibular syndrome \| Episodic vestibular syndrome in diseases classified elsewhere \| Episodic vestibular syndrome due to cerebrovascular disease \| Episodic vestibular syndrome due to diseases of the circulatory system [6C45.0] Episode of harmful use of cocaine Definition: An episode of use of cocaine that has caused damage to a person’s physical or mental health or has resulted in behaviour leading to harm to the health of others. Harm to health of the individual occurs due to one or more of the following: (1) behaviour related to intoxication; (2) direct or secondary toxic effects on body organs and systems; or (3) a harmful route of administration. Harm to health of others includes any form of physical harm, including trauma, or mental disorder that is directly Also known as: Episode of harmful use of cocaine Excludes: Cocaine dependence \| Harmful pattern of use of cocaine [5A41] Hypoglycaemia without associated diabetes Also known as: Hypoglycaemia without associated diabetes \| low blood sugar \| hypoglycaemia NOS \| spontaneous hypoglycaemia \| nondiabetic hypoglycaemia Excludes: Hypoglycaemia in the context of diabetes mellitus [5A4Z] Disorders of glucose regulation or pancreatic internal secretion, unspecified Also known as: Disorders of glucose regulation or pancreatic internal secretion, unspecified [5A45] Persistent hyperinsulinaemic hypoglycaemia of infancy Definition: Congenital isolated hyperinsulinism, or Persistent hyperinsulinaemic hypoglycaemia of infancy (PHHI) is defined by an inappropriate oversecretion of insulin by the endocrine pancreas that is responsible for profound hypoglycaemia, which requires aggressive medical and/or surgical treatment to prevent severe and irreversible brain damage. PHHI is a genetically heterogeneous disorder with two types of histological lesions: diffuse (DiPHHI) and focal (FoPHHI) which are clinically indistinguishable. Also known as: Persistent hyperinsulinaemic hypoglycaemia of infancy \| PHHI - [Persistent hyperinsulinaemic hypoglycaemia of infancy] \| hypoglycaemia of infancy \| infantile hypoglycaemia \| infantile spontaneous hypoglycaemia [KB60.4Z] Neonatal hypoglycaemia, unspecified Also known as: Neonatal hypoglycaemia, unspecified \| Neonatal hypoglycaemia [8D8D] Hypoglycaemia unawareness Definition: Hypoglycemia unawareness is defined at the onset of neuroglycopenia before the appearance of autonomic warning symptoms Also known as: Hypoglycaemia unawareness === GRAPH WALKS === --- Walk 1 --- [8A68.Y] Other specified type of seizure --PARENT--> [8A68] Types of seizures --CHILD--> [8A68.0] Focal unaware seizure Def: Previously termed “complex partial seizures”, define seizures originating within networks limited to one hemisphere and accompanied by loss of awareness (i.e., knowledge of self or environment).... --- Walk 2 --- [8A68.Y] Other specified type of seizure --PARENT--> [8A68] Types of seizures --CHILD--> [8A68.1] Absence seizures, atypical Def: Absence seizures with changes in tone more pronounced than in typical absences or with non-abrupt onset and/or cessation, often associated with slow, irregular, generalised spike-wave activity.... --- Walk 3 --- [MD11.1] Asphyxia Def: Asphyxia is a life-threatening condition in which oxygen is prevented from reaching the tissues by obstruction of or damage to any part of the respiratory system. More generally the term indicates all... --EXCLUDES--> [?] Harmful effects of or exposure to noxious substances, substances chiefly nonmedicinal as to source, carbon monoxide Def: Inhalation of carbon monoxide results in neurotoxicity, cardiotoxicity, haematotoxicity, pneumotoxicity and fetotoxicity. Use additional extension code, if desired, to identify substance.... --CHILD--> [?] Harmful effects of or exposure to noxious substances, Substances chiefly nonmedicinal as to source, Carbon monoxide, Carbon monoxide from incomplete combustion of other domestic fuels --- Walk 4 --- [MD11.1] Asphyxia Def: Asphyxia is a life-threatening condition in which oxygen is prevented from reaching the tissues by obstruction of or damage to any part of the respiratory system. More generally the term indicates all... --RELATED_TO--> [?] Intrauterine hypoxia Def: Intrauterine hypoxia occurs when the fetus is deprived of an adequate supply of oxygen. This may occur with prolapse or occlusion of the umbilical cord, placental infarction and maternal smoking. This... --EXCLUDES--> [?] Intracranial nontraumatic haemorrhage of fetus or newborn Def: Intraventricular (nontraumatic) haemorrhage of the fetus and newborn is a condition characterised by bleeding within the skull of a newborn that is not due to injury causing physical damage.... --- Walk 5 --- [AB31.Z] Episodic vestibular syndrome, unspecified --PARENT--> [AB31] Episodic vestibular syndrome Def: A clinical syndrome of transient vertigo, dizziness, or unsteadiness lasting seconds to hours, occasionally days, and generally including features suggestive of temporary, short-lived vestibular syste... --RELATED_TO--> [?] Benign paroxysmal vertigo of childhood Def: This probably heterogeneous disorder is characterised by recurrent brief episodic attacks of vertigo occurring without warning and resolving spontaneously in otherwise healthy children.... --- Walk 6 --- [AB31.Z] Episodic vestibular syndrome, unspecified --PARENT--> [AB31] Episodic vestibular syndrome Def: A clinical syndrome of transient vertigo, dizziness, or unsteadiness lasting seconds to hours, occasionally days, and generally including features suggestive of temporary, short-lived vestibular syste... --CHILD--> [AB31.0] Meniere disease Def: Meniere Disease (MD) is a chronic progressive inner ear disease, with endolymphatic hydrops. It is characterised by recurrent attacks of debilitating spontaneous vertigo lasting from 20 minutes to up ...	[ "[8A68.Y] Other specified type of seizure\n --PARENT--> [8A68] Types of seizures\n --CHILD--> [8A68.0] Focal unaware seizure\n Def: Previously termed “complex partial seizures”, define seizures originating within networks limited to one hemisphere and accompanied by loss of awareness (i.e., knowledge of self or environment)....", "[8A68.Y] Other specified type of seizure\n --PARENT--> [8A68] Types of seizures\n --CHILD--> [8A68.1] Absence seizures, atypical\n Def: Absence seizures with changes in tone more pronounced than in typical absences or with non-abrupt onset and/or cessation, often associated with slow, irregular, generalised spike-wave activity....", "[MD11.1] Asphyxia\n Def: Asphyxia is a life-threatening condition in which oxygen is prevented from reaching the tissues by obstruction of or damage to any part of the respiratory system. More generally the term indicates all...\n --EXCLUDES--> [?] Harmful effects of or exposure to noxious substances, substances chiefly nonmedicinal as to source, carbon monoxide\n Def: Inhalation of carbon monoxide results in neurotoxicity, cardiotoxicity, haematotoxicity, pneumotoxicity and fetotoxicity.\n\nUse additional extension code, if desired, to identify substance....\n --CHILD--> [?] Harmful effects of or exposure to noxious substances, Substances chiefly nonmedicinal as to source, Carbon monoxide, Carbon monoxide from incomplete combustion of other domestic fuels", "[MD11.1] Asphyxia\n Def: Asphyxia is a life-threatening condition in which oxygen is prevented from reaching the tissues by obstruction of or damage to any part of the respiratory system. More generally the term indicates all...\n --RELATED_TO--> [?] Intrauterine hypoxia\n Def: Intrauterine hypoxia occurs when the fetus is deprived of an adequate supply of oxygen. This may occur with prolapse or occlusion of the umbilical cord, placental infarction and maternal smoking. This...\n --EXCLUDES--> [?] Intracranial nontraumatic haemorrhage of fetus or newborn\n Def: Intraventricular (nontraumatic) haemorrhage of the fetus and newborn is a condition characterised by bleeding within the skull of a newborn that is not due to injury causing physical damage....", "[AB31.Z] Episodic vestibular syndrome, unspecified\n --PARENT--> [AB31] Episodic vestibular syndrome\n Def: A clinical syndrome of transient vertigo, dizziness, or unsteadiness lasting seconds to hours, occasionally days, and generally including features suggestive of temporary, short-lived vestibular syste...\n --RELATED_TO--> [?] Benign paroxysmal vertigo of childhood\n Def: This probably heterogeneous disorder is characterised by recurrent brief episodic attacks of vertigo occurring without warning and resolving spontaneously in otherwise healthy children....", "[AB31.Z] Episodic vestibular syndrome, unspecified\n --PARENT--> [AB31] Episodic vestibular syndrome\n Def: A clinical syndrome of transient vertigo, dizziness, or unsteadiness lasting seconds to hours, occasionally days, and generally including features suggestive of temporary, short-lived vestibular syste...\n --CHILD--> [AB31.0] Meniere disease\n Def: Meniere Disease (MD) is a chronic progressive inner ear disease, with endolymphatic hydrops. It is characterised by recurrent attacks of debilitating spontaneous vertigo lasting from 20 minutes to up ..." ]	8A68.Y	Other specified type of seizure	[ { "from_icd11": "MD11.1", "icd10_code": "R0901", "icd10_title": "Asphyxia" }, { "from_icd11": "MD11.1", "icd10_code": "R0902", "icd10_title": "Hypoxemia" }, { "from_icd11": "MD11.1", "icd10_code": "R090", "icd10_title": "Asphyxia and hypoxemia" }, { "from_icd11": "5A41", "icd10_code": "E162", "icd10_title": "Hypoglycemia, unspecified" }, { "from_icd11": "5A41", "icd10_code": "E160", "icd10_title": "Drug-induced hypoglycemia without coma" }, { "from_icd11": "5A41", "icd10_code": "E15", "icd10_title": "Nondiabetic hypoglycemic coma" }, { "from_icd11": "5A4Z", "icd10_code": "E161", "icd10_title": "Other hypoglycemia" }, { "from_icd11": "5A4Z", "icd10_code": "E168", "icd10_title": "Other specified disorders of pancreatic internal secretion" }, { "from_icd11": "5A4Z", "icd10_code": "E169", "icd10_title": "Disorder of pancreatic internal secretion, unspecified" }, { "from_icd11": "5A4Z", "icd10_code": "E15-E16", "icd10_title": "" }, { "from_icd11": "5A4Z", "icd10_code": "E16", "icd10_title": "Other disorders of pancreatic internal secretion" }, { "from_icd11": "KB60.4Z", "icd10_code": "P703", "icd10_title": "Iatrogenic neonatal hypoglycemia" }, { "from_icd11": "KB60.4Z", "icd10_code": "P704", "icd10_title": "Other neonatal hypoglycemia" } ]	R0901	Asphyxia
An 86-year-old man with a medical history of atrial fibrillation, coronary artery disease, hypertension, and a recent gastrointestinal bleed due to diverticulosis presented for a Watchman FLX implantation procedure. The physical examination and laboratory data were unremarkable. The procedure was performed through right femoral vein access under transesophageal echocardiogram (TEE) guidance and general anesthesia. A 16-French (Fr) sheath was inserted into the right femoral vein, and an 8-Fr Baylis trans-septal sheath was advanced through the large-bore sheath and into the right atrium over the VersaCross trans-septal guidewire. A trans-septal puncture was performed under TEE guidance using the VersaCross trans-septal guidewire and trans-septal sheath in the standard fashion . The VersaCross trans-septal guidewire was then advanced into the left superior pulmonary vein, and the trans-septal sheath was removed. A 14-Fr Watchman FLX double-curve delivery sheath was advanced into the left atrium over the VersaCross trans-septal guidewire. After the removal of the VersaCross trans-septal guidewire, a 5 Fr pigtail catheter was placed in the left atrial appendage through the Watchman FLX delivery sheath. IV contrast was injected through the pigtail catheter to visualize the left atrial appendage . Echocardiographic and fluoroscopic measurements were collected, and a 27-mm Watchman FLX device was selected.	3.927734	0.975098	sec[1]/p[0]	en	0.999999	PMC10083151	https://doi.org/10.7759/cureus.36002	[ "trans", "septal", "sheath", "versacross", "guidewire", "watchman", "atrial", "vein", "advanced", "femoral" ]	[ { "code": "5C50.B", "title": "Disorders of methionine cycle or sulphur amino acid metabolism" }, { "code": "HA60", "title": "Gender incongruence of adolescence or adulthood" }, { "code": "LD40.0", "title": "Complete trisomy 21" }, { "code": "QB63.7", "title": "Presence of transfused blood" }, { "code": "DB36.11", "title": "Ischiorectal abscess" }, { "code": "LA88.Z", "title": "Congenital anomaly of a ventricle or the ventricular septum, unspecified" }, { "code": "LA8E.Z", "title": "Congenital anomaly of atrial septum, unspecified" }, { "code": "LA88.4Z", "title": "Ventricular septal defect, unspecified" }, { "code": "LA8B.0", "title": "Congenital aortopulmonary window" }, { "code": "BC43.1Y", "title": "Other specified hypertrophic cardiomyopathy" } ]	=== ICD-11 CODES FOUND === [5C50.B] Disorders of methionine cycle or sulphur amino acid metabolism Also known as: Disorders of methionine cycle or sulphur amino acid metabolism \| disorder of sulphur-bearing amino acid including those due to folate and b12 disturbance \| disorder of sulphur-bearing amino acid metabolism \| disorder of transsulfuration \| disorder of transsulphuration [HA60] Gender incongruence of adolescence or adulthood Definition: Gender Incongruence of Adolescence and Adulthood is characterised by a marked and persistent incongruence between an individual’s experienced gender and the assigned sex, which often leads to a desire to ‘transition’, in order to live and be accepted as a person of the experienced gender, through hormonal treatment, surgery or other health care services to make the individual’s body align, as much as desired and to the extent possible, with the experienced gender. The diagnosis cannot be assigne Also known as: Gender incongruence of adolescence or adulthood \| trans-sexualism (deprecated) \| gender dysphoria in adolescents and adults (deprecated) \| transsexual (deprecated) Excludes: Paraphilic disorders [LD40.0] Complete trisomy 21 Definition: Trisomy 21 is a chromosomal abnormality, characterised by the presence of a third (partial or total) copy of chromosome 21, which clinical manifestations include variable intellectual deficiency, muscular hypotonia and joint laxity, often associated with facial dysmorphism and variable malformations (essentially heart and digestive) and a risk of complications (epilepsy, leukemia, auto-immune and endocrine pathologies, earlier aging and Alzheimer disease. Also known as: Complete trisomy 21 \| Down syndrome \| Chromosome 21 trisomy \| Trisomy 21 syndrome \| Trisomy 21 NOS Includes: Down syndrome [QB63.7] Presence of transfused blood Also known as: Presence of transfused blood \| blood transplant status \| blood transfusion status \| presence of transplanted blood [DB36.11] Ischiorectal abscess Definition: A condition of the rectum, caused by an infection with a bacterial, viral, or fungal source. This condition is characterised by a focal accumulation of purulent material in the ischiorectal space. This condition presents with pain in the perianal region, back pain, swelling, or fever. Confirmation is commonly by advanced imaging. Also known as: Ischiorectal abscess \| Abscess of ischiorectal fossa \| Ischiorectal fistula \| ischiorectal fossa fistula \| Transsphincteric anal fistula Includes: Abscess of ischiorectal fossa [LA88.Z] Congenital anomaly of a ventricle or the ventricular septum, unspecified Also known as: Congenital anomaly of a ventricle or the ventricular septum, unspecified \| Congenital anomaly of a ventricle or the ventricular septum [LA8E.Z] Congenital anomaly of atrial septum, unspecified Also known as: Congenital anomaly of atrial septum, unspecified \| Congenital anomaly of atrial septum \| congenital malformation of atrial septum [LA88.4Z] Ventricular septal defect, unspecified Also known as: Ventricular septal defect, unspecified \| Ventricular septal defect \| interventricular septal defect \| interventricular septum defect \| ventricular septum defect [LA8B.0] Congenital aortopulmonary window Definition: A congenital cardiovascular malformation in which there is side-to-side continuity of the lumens of the ascending aorta and pulmonary trunk in association with separate aortic and pulmonary valves or their atretic remnants. Additional information: side-to-side continuity of the lumens of the aorta and pulmonary arterial tree, which is distinguished from common arterial trunk (truncus arteriosus) by the presence of two arterial valves or their atretic remnants, and involvement of the pulmonary t Also known as: Congenital aortopulmonary window \| aorticopulmonary window \| aorticopulmonary fenestration \| aorticopulmonary septal defect \| aortopulmonary septal defect Includes: Aortic septal defect \| Aortopulmonary window [BC43.1Y] Other specified hypertrophic cardiomyopathy Also known as: Other specified hypertrophic cardiomyopathy \| Nonfamilial hypertrophic cardiomyopathy \| Idiopathic isolated hypertrophic cardiomyopathy \| Asymmetrical hypertrophy \| Asymmetrical septal hypertrophy === GRAPH WALKS === --- Walk 1 --- [5C50.B] Disorders of methionine cycle or sulphur amino acid metabolism --RELATED_TO--> [?] Hereditary megaloblastic anaemia due to transcobalamin deficiency Def: A disease caused by defective intestinal absorption of vitamin B12 due to autosomal recessive genetic mutation. This disease may present with vomiting, poor growth, infections due to hypogammaglobulin... --PARENT--> [?] Disorders of methionine cycle or sulphur amino acid metabolism --- Walk 2 --- [5C50.B] Disorders of methionine cycle or sulphur amino acid metabolism --RELATED_TO--> [?] Hereditary megaloblastic anaemia due to transcobalamin deficiency Def: A disease caused by defective intestinal absorption of vitamin B12 due to autosomal recessive genetic mutation. This disease may present with vomiting, poor growth, infections due to hypogammaglobulin... --PARENT--> [?] Disorders of methionine cycle or sulphur amino acid metabolism --- Walk 3 --- [HA60] Gender incongruence of adolescence or adulthood Def: Gender Incongruence of Adolescence and Adulthood is characterised by a marked and persistent incongruence between an individual’s experienced gender and the assigned sex, which often leads to a desire... --PARENT--> [?] Gender incongruence Def: Gender incongruence is characterised by a marked and persistent incongruence between an individual’s experienced gender and the assigned sex. Gender variant behaviour and preferences alone are not a b... --EXCLUDES--> [?] Paraphilic disorders Def: Paraphilic disorders are characterised by persistent and intense patterns of atypical sexual arousal, manifested by sexual thoughts, fantasies, urges, or behaviours, the focus of which involves others... --- Walk 4 --- [HA60] Gender incongruence of adolescence or adulthood Def: Gender Incongruence of Adolescence and Adulthood is characterised by a marked and persistent incongruence between an individual’s experienced gender and the assigned sex, which often leads to a desire... --EXCLUDES--> [?] Paraphilic disorders Def: Paraphilic disorders are characterised by persistent and intense patterns of atypical sexual arousal, manifested by sexual thoughts, fantasies, urges, or behaviours, the focus of which involves others... --CHILD--> [?] Pedophilic disorder Def: Pedophilic disorder is characterised by a sustained, focused, and intense pattern of sexual arousal—as manifested by persistent sexual thoughts, fantasies, urges, or behaviours—involving pre-pubertal ... --- Walk 5 --- [LD40.0] Complete trisomy 21 Def: Trisomy 21 is a chromosomal abnormality, characterised by the presence of a third (partial or total) copy of chromosome 21, which clinical manifestations include variable intellectual deficiency, musc... --PARENT--> [LD40] Complete trisomies of the autosomes Def: Any disease caused by the presence of one extra autosome, for a total of three. Confirmation is through observation of a supernumerary autosome by karyotyping.... --CHILD--> [LD40.2] Complete trisomy 18 Def: Trisomy 18 is a chromosomal abnormality associated with the presence of an extra chromosome 18 and characterised by growth delay, dolichocephaly, a characteristic facies, limb anomalies and visceral m... --- Walk 6 --- [LD40.0] Complete trisomy 21 Def: Trisomy 21 is a chromosomal abnormality, characterised by the presence of a third (partial or total) copy of chromosome 21, which clinical manifestations include variable intellectual deficiency, musc... --RELATED_TO--> [?] Keratoconus in Down syndrome --PARENT--> [?] Keratoconus Def: Keratoconus is a noninflammatory, often bilateral, corneal dystrophy characterised by progressive cone-shaped bulging and thinning of the cornea....	[ "[5C50.B] Disorders of methionine cycle or sulphur amino acid metabolism\n --RELATED_TO--> [?] Hereditary megaloblastic anaemia due to transcobalamin deficiency\n Def: A disease caused by defective intestinal absorption of vitamin B12 due to autosomal recessive genetic mutation. This disease may present with vomiting, poor growth, infections due to hypogammaglobulin...\n --PARENT--> [?] Disorders of methionine cycle or sulphur amino acid metabolism", "[5C50.B] Disorders of methionine cycle or sulphur amino acid metabolism\n --RELATED_TO--> [?] Hereditary megaloblastic anaemia due to transcobalamin deficiency\n Def: A disease caused by defective intestinal absorption of vitamin B12 due to autosomal recessive genetic mutation. This disease may present with vomiting, poor growth, infections due to hypogammaglobulin...\n --PARENT--> [?] Disorders of methionine cycle or sulphur amino acid metabolism", "[HA60] Gender incongruence of adolescence or adulthood\n Def: Gender Incongruence of Adolescence and Adulthood is characterised by a marked and persistent incongruence between an individual’s experienced gender and the assigned sex, which often leads to a desire...\n --PARENT--> [?] Gender incongruence\n Def: Gender incongruence is characterised by a marked and persistent incongruence between an individual’s experienced gender and the assigned sex. Gender variant behaviour and preferences alone are not a b...\n --EXCLUDES--> [?] Paraphilic disorders\n Def: Paraphilic disorders are characterised by persistent and intense patterns of atypical sexual arousal, manifested by sexual thoughts, fantasies, urges, or behaviours, the focus of which involves others...", "[HA60] Gender incongruence of adolescence or adulthood\n Def: Gender Incongruence of Adolescence and Adulthood is characterised by a marked and persistent incongruence between an individual’s experienced gender and the assigned sex, which often leads to a desire...\n --EXCLUDES--> [?] Paraphilic disorders\n Def: Paraphilic disorders are characterised by persistent and intense patterns of atypical sexual arousal, manifested by sexual thoughts, fantasies, urges, or behaviours, the focus of which involves others...\n --CHILD--> [?] Pedophilic disorder\n Def: Pedophilic disorder is characterised by a sustained, focused, and intense pattern of sexual arousal—as manifested by persistent sexual thoughts, fantasies, urges, or behaviours—involving pre-pubertal ...", "[LD40.0] Complete trisomy 21\n Def: Trisomy 21 is a chromosomal abnormality, characterised by the presence of a third (partial or total) copy of chromosome 21, which clinical manifestations include variable intellectual deficiency, musc...\n --PARENT--> [LD40] Complete trisomies of the autosomes\n Def: Any disease caused by the presence of one extra autosome, for a total of three. Confirmation is through observation of a supernumerary autosome by karyotyping....\n --CHILD--> [LD40.2] Complete trisomy 18\n Def: Trisomy 18 is a chromosomal abnormality associated with the presence of an extra chromosome 18 and characterised by growth delay, dolichocephaly, a characteristic facies, limb anomalies and visceral m...", "[LD40.0] Complete trisomy 21\n Def: Trisomy 21 is a chromosomal abnormality, characterised by the presence of a third (partial or total) copy of chromosome 21, which clinical manifestations include variable intellectual deficiency, musc...\n --RELATED_TO--> [?] Keratoconus in Down syndrome\n --PARENT--> [?] Keratoconus\n Def: Keratoconus is a noninflammatory, often bilateral, corneal dystrophy characterised by progressive cone-shaped bulging and thinning of the cornea...." ]	5C50.B	Disorders of methionine cycle or sulphur amino acid metabolism	[ { "from_icd11": "5C50.B", "icd10_code": "E7212", "icd10_title": "Methylenetetrahydrofolate reductase deficiency" }, { "from_icd11": "5C50.B", "icd10_code": "E7211", "icd10_title": "Homocystinuria" }, { "from_icd11": "5C50.B", "icd10_code": "E7210", "icd10_title": "Disorders of sulfur-bearing amino-acid metabolism, unspecified" }, { "from_icd11": "5C50.B", "icd10_code": "E7219", "icd10_title": "Other disorders of sulfur-bearing amino-acid metabolism" }, { "from_icd11": "5C50.B", "icd10_code": "E721", "icd10_title": "Disorders of sulfur-bearing amino-acid metabolism" }, { "from_icd11": "HA60", "icd10_code": "F649", "icd10_title": "Gender identity disorder, unspecified" }, { "from_icd11": "HA60", "icd10_code": "F640", "icd10_title": "Transsexualism" }, { "from_icd11": "LD40.0", "icd10_code": "Q909", "icd10_title": "Down syndrome, unspecified" }, { "from_icd11": "LD40.0", "icd10_code": "Q902", "icd10_title": "Trisomy 21, translocation" }, { "from_icd11": "LD40.0", "icd10_code": "Q90", "icd10_title": "Down syndrome" }, { "from_icd11": "LD40.0", "icd10_code": "Q900", "icd10_title": "Trisomy 21, nonmosaicism (meiotic nondisjunction)" }, { "from_icd11": "LD40.0", "icd10_code": "Q901", "icd10_title": "Trisomy 21, mosaicism (mitotic nondisjunction)" }, { "from_icd11": "DB36.11", "icd10_code": "K6131", "icd10_title": "Horseshoe abscess" }, { "from_icd11": "DB36.11", "icd10_code": "K6139", "icd10_title": "Other ischiorectal abscess" }, { "from_icd11": "DB36.11", "icd10_code": "K613", "icd10_title": "Ischiorectal abscess" } ]	E7212	Methylenetetrahydrofolate reductase deficiency
Fractures in the anterolateral aspect of the distal tibia are frequently caused by avulsion of the anterior tibial tubercle, due to anterior-inferior tibiofibular ligament failing to rupture during injury, resulting in a juvenile Tillaux fracture in adolescents (Salter-Harris type III fracture) and a Tillaux fracture in adults . The classification of this type of adult Tillaux fracture is type A, and if accompanied by medial injury, it is classified as type B . The first report of this injury was by Cooper in 1822 , followed by Tillaux in 1848 . The mechanism of injury for this fracture pattern, according to previous studies, is external rotation of the foot relative to the tibia . Although it is typically observed in pediatric and adolescent populations and classified as a Salter-Harris III fracture through the epiphysis, it has been rarely reported in older populations. While it is frequently observed in children aged 12 to 14 years , it has also been documented in young adults and those who have reached skeletal maturity , potentially due to delayed ossification of the growth plate. The goal of this case report is to present a unique case of tibial plafond fracture in an older adult mimicking the fracture geometry seen in a Tillaux fracture, emphasizing the importance of its accurate diagnosis to avoid possible complications such as premature degenerative arthritis and restricted ankle mobility.	4.191406	0.935059	sec[0]/p[0]	en	0.999993	PMC10148674	https://doi.org/10.7759/cureus.36910	[ "fracture", "tillaux", "injury", "type", "this", "tibia", "frequently", "tibial", "salter", "harris" ]	[ { "code": "ND56.2", "title": "Fracture of unspecified body region" }, { "code": "ND32", "title": "Fractures involving multiple body regions" }, { "code": "NB52.Z", "title": "Fracture of lumbar spine or pelvis, unspecified" }, { "code": "FB80.B", "title": "Pathological fracture" }, { "code": "FB80.Y", "title": "Other specified disorders of bone density or structure" }, { "code": "ND56.Z", "title": "Unspecified injury to unspecified part of trunk, limb or body region" }, { "code": "ND37", "title": "Unspecified multiple injuries" }, { "code": "NB91.Y&XA9607", "title": "Injury of intestine" }, { "code": "ND56.4", "title": "Injury of nerve of unspecified body region" }, { "code": "NF0A.Z", "title": "Early complications of trauma, not elsewhere classified" } ]	=== ICD-11 CODES FOUND === [ND56.2] Fracture of unspecified body region Also known as: Fracture of unspecified body region \| avulsion fracture of unspecified body site \| comminuted fracture of unspecified body site \| compression fracture of unspecified body site \| fracture dislocation of unspecified body site Excludes: multiple fractures NOS [ND32] Fractures involving multiple body regions Also known as: Fractures involving multiple body regions \| multiple skeletal fractures \| multiple fractures \| multiple compression fractures \| fracture of multiple bone sites [NB52.Z] Fracture of lumbar spine or pelvis, unspecified Also known as: Fracture of lumbar spine or pelvis, unspecified \| Fracture of lumbar spine or pelvis \| Fracture of pelvis, not elsewhere classified \| fracture pelvis NOS \| pelvic fracture [FB80.B] Pathological fracture Also known as: Pathological fracture \| pathological bone fracture \| Pathological fracture NOS \| spontaneous fracture \| spontaneous fracture with dislocation Excludes: Collapsed vertebra, not elsewhere classified [FB80.Y] Other specified disorders of bone density or structure Also known as: Other specified disorders of bone density or structure \| Bone dysplasia \| Inherited bone dysplasia \| Acquired bone dysplasia \| Drug-induced bone dysplasia [ND56.Z] Unspecified injury to unspecified part of trunk, limb or body region Also known as: Unspecified injury to unspecified part of trunk, limb or body region \| Injury of unspecified body region \| injury NOS \| trauma NOS \| traumatic injury NOS [ND37] Unspecified multiple injuries Also known as: Unspecified multiple injuries \| multiple trauma NOS \| multiple traumatic injuries \| multiple sites of injury \| multiple system injury Excludes: injury NOS [ND56.4] Injury of nerve of unspecified body region Also known as: Injury of nerve of unspecified body region \| injuries to nerves, nerve plexuses and roots \| injury to nerves, unspecified site \| nerve damage NOS \| Injury of nerve NOS Excludes: multiple injuries of nerves NOS [NF0A.Z] Early complications of trauma, not elsewhere classified Also known as: Early complications of trauma, not elsewhere classified \| Certain early complications of trauma, not elsewhere classified \| early trauma complications \| early complication of trauma \| trauma complications === GRAPH WALKS === --- Walk 1 --- [ND56.2] Fracture of unspecified body region --PARENT--> [ND56] Injury of unspecified body region Def: Damage inflicted on the body in an unspecified area as the direct or indirect result of an external force, with or without disruption of structural continuity.... --PARENT--> [?] Injuries to unspecified part of trunk, limb or body region --- Walk 2 --- [ND56.2] Fracture of unspecified body region --EXCLUDES--> [?] Fractures involving multiple body regions --CHILD--> [?] Fractures involving thorax with lower back or pelvis --- Walk 3 --- [ND32] Fractures involving multiple body regions --PARENT--> [?] Injuries involving multiple body regions --EXCLUDES--> [?] Burns Def: A burn is an injury to the tissues caused by a pathological flux of energy which causes cellular destruction and irreversible denaturation of proteins and is primarily caused by thermal or other acute... --- Walk 4 --- [ND32] Fractures involving multiple body regions --RELATED_TO--> [?] Fractures involving multiple body regions due to birth injury Def: A condition characterised by the presence of skeletal fractures in more than one body region due to physical pressure or injury during delivery.... --PARENT--> [?] Fractures involving multiple body regions --- Walk 5 --- [NB52.Z] Fracture of lumbar spine or pelvis, unspecified --PARENT--> [NB52] Fracture of lumbar spine or pelvis Def: Broken bone in the lumbar spine or pelvis.... --EXCLUDES--> [?] Fracture of neck of femur --- Walk 6 --- [NB52.Z] Fracture of lumbar spine or pelvis, unspecified --PARENT--> [NB52] Fracture of lumbar spine or pelvis Def: Broken bone in the lumbar spine or pelvis.... --CHILD--> [NB52.0] Fracture of lumbar vertebra	[ "[ND56.2] Fracture of unspecified body region\n --PARENT--> [ND56] Injury of unspecified body region\n Def: Damage inflicted on the body in an unspecified area as the direct or indirect result of an external force, with or without disruption of structural continuity....\n --PARENT--> [?] Injuries to unspecified part of trunk, limb or body region", "[ND56.2] Fracture of unspecified body region\n --EXCLUDES--> [?] Fractures involving multiple body regions\n --CHILD--> [?] Fractures involving thorax with lower back or pelvis", "[ND32] Fractures involving multiple body regions\n --PARENT--> [?] Injuries involving multiple body regions\n --EXCLUDES--> [?] Burns\n Def: A burn is an injury to the tissues caused by a pathological flux of energy which causes cellular destruction and irreversible denaturation of proteins and is primarily caused by thermal or other acute...", "[ND32] Fractures involving multiple body regions\n --RELATED_TO--> [?] Fractures involving multiple body regions due to birth injury\n Def: A condition characterised by the presence of skeletal fractures in more than one body region due to physical pressure or injury during delivery....\n --PARENT--> [?] Fractures involving multiple body regions", "[NB52.Z] Fracture of lumbar spine or pelvis, unspecified\n --PARENT--> [NB52] Fracture of lumbar spine or pelvis\n Def: Broken bone in the lumbar spine or pelvis....\n --EXCLUDES--> [?] Fracture of neck of femur", "[NB52.Z] Fracture of lumbar spine or pelvis, unspecified\n --PARENT--> [NB52] Fracture of lumbar spine or pelvis\n Def: Broken bone in the lumbar spine or pelvis....\n --CHILD--> [NB52.0] Fracture of lumbar vertebra" ]	ND56.2	Fracture of unspecified body region	[ { "from_icd11": "ND56.2", "icd10_code": "T142", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T02", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T020", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T021", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T022", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T023", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T024", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T025", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T026", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T027", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T028", "icd10_title": "" }, { "from_icd11": "ND32", "icd10_code": "T029", "icd10_title": "" }, { "from_icd11": "NB52.Z", "icd10_code": "S329XXD", "icd10_title": "Fracture of unspecified parts of lumbosacral spine and pelvis, subsequent encounter for fracture with routine healing" }, { "from_icd11": "NB52.Z", "icd10_code": "S32601A", "icd10_title": "Unspecified fracture of right ischium, initial encounter for closed fracture" }, { "from_icd11": "NB52.Z", "icd10_code": "S329XXG", "icd10_title": "Fracture of unspecified parts of lumbosacral spine and pelvis, subsequent encounter for fracture with delayed healing" } ]	T142
During the diagnostic workup in a neighbouring general hospital an MRI scan of the spinal cord was performed ( Figure 1(a) ). It showed a spinal vascular malformation with a large aneurysm at the level of the lower thoracic spinal cord, causing massive compression of the lumbar spinal cord. The boy was transferred to our university hospital for further diagnosis. Spinal angiography (under general anaesthesia) identified the vascular malformation as a spinal arteriovenous fistula with an associated large venous aneurysm at the level of the fistula. The dilated arterial feeder as recognized from MRI originated from the intercostal artery at T9. It was thought to be a single fistula. Due to the low weight of the boy, only a limited amount of contrast could be administered and more distal thoracic levels were not checked. An embolisation of this AVF at T9 was carried out, using a coil and a liquid embolic agent . The idea was that the aneurysm would gradually shrink in time, whereas initial aneurysm occlusion would result in an oedematous reaction with increase in spinal cord compression. Postoperative high-dose dexamethasone was given to prevent oedema of the spinal cord. The boy recovered well with spontaneous movements of the lower limbs and preservation of sensibility. Because of his symptoms and the family history, genetic testing was started up to try and confirm the diagnosis of ROWD in the boy.	3.945313	0.976074	sec[1]/p[1]	en	0.999997	24707424	https://doi.org/10.1155/2014/696703	[ "spinal", "cord", "aneurysm", "fistula", "general", "vascular", "malformation", "large", "thoracic", "compression" ]	[ { "code": "FB1Z", "title": "Conditions associated with the spine, unspecified" }, { "code": "FA7Z", "title": "Structural disorders of spine, unspecified" }, { "code": "FA9Z", "title": "Inflammation of spine, unspecified" }, { "code": "LB73.2Z", "title": "Structural developmental anomalies of spine, unspecified" }, { "code": "FA82", "title": "Spinal stenosis" }, { "code": "JB08.5", "title": "Labour or delivery complicated by other cord entanglement, with compression" }, { "code": "8A40.Z", "title": "Multiple sclerosis, unspecified" }, { "code": "ND51.1", "title": "Injury of unspecified nerve, spinal nerve root or plexus of trunk" }, { "code": "GB0Y", "title": "Other specified diseases of the male genital system" }, { "code": "8B41", "title": "Myelitis" } ]	=== ICD-11 CODES FOUND === [FB1Z] Conditions associated with the spine, unspecified Also known as: Conditions associated with the spine, unspecified \| dorsopathies \| disorder of spine \| spinal disorder [FA7Z] Structural disorders of spine, unspecified Also known as: Structural disorders of spine, unspecified \| spinal disease [FA9Z] Inflammation of spine, unspecified Also known as: Inflammation of spine, unspecified \| spinal inflammation \| discitis, unspecified [LB73.2Z] Structural developmental anomalies of spine, unspecified Also known as: Structural developmental anomalies of spine, unspecified \| Structural developmental anomalies of spine \| Malformations of spine \| maldevelopment of spine [FA82] Spinal stenosis Definition: This is a condition characterised by narrowing of the spinal canal. Also known as: Spinal stenosis \| spinal canal stenosis \| Spinal stenosis with no determinant \| primary spinal stenosis \| Spinal stenosis with determinant [JB08.5] Labour or delivery complicated by other cord entanglement, with compression Also known as: Labour or delivery complicated by other cord entanglement, with compression \| labour and delivery complicated by other cord entanglement \| Compression of cord NOS \| umbilical cord compression, complicating delivery \| umbilical cord entanglement [8A40.Z] Multiple sclerosis, unspecified Also known as: Multiple sclerosis, unspecified \| Multiple sclerosis \| cerebrospinal sclerosis \| disseminated sclerosis \| generalised multiple sclerosis [ND51.1] Injury of unspecified nerve, spinal nerve root or plexus of trunk Also known as: Injury of unspecified nerve, spinal nerve root or plexus of trunk \| spinal nerve injury \| injury of spinal nerve root \| injury of spinal nerve plexus \| injury of spinal cord plexus [GB0Y] Other specified diseases of the male genital system Also known as: Other specified diseases of the male genital system \| Diseases of male genital organs \| disease or disorder of male genitourinary system \| Pain in scrotum \| scrotal pain [8B41] Myelitis Also known as: Myelitis \| spinal cord inflammation NOS \| radiculomyelitis NOS \| myeloradiculitis \| Myelitis due to noninfectious, inflammatory or autoimmune disorders === GRAPH WALKS === --- Walk 1 --- [FB1Z] Conditions associated with the spine, unspecified --PARENT--> [?] Conditions associated with the spine Def: This is a group of conditions in which there is a deviation from or interruption of the normal structure or function of the spine.... --RELATED_TO--> [?] Neck syndrome --- Walk 2 --- [FB1Z] Conditions associated with the spine, unspecified --PARENT--> [?] Conditions associated with the spine Def: This is a group of conditions in which there is a deviation from or interruption of the normal structure or function of the spine.... --CHILD--> [?] Structural disorders of spine --- Walk 3 --- [FA7Z] Structural disorders of spine, unspecified --PARENT--> [?] Structural disorders of spine --CHILD--> [FA70] Spinal deformities --- Walk 4 --- [FA7Z] Structural disorders of spine, unspecified --PARENT--> [?] Structural disorders of spine --CHILD--> [FA71] Torticollis --- Walk 5 --- [FA9Z] Inflammation of spine, unspecified --PARENT--> [?] Inflammation of spine --CHILD--> [FA90] Infection of vertebra Def: A condition of the vertebrae, caused by an infection with a bacterial, viral, fungal, or parasitic source. This condition commonly presents with fever, chills, headache, weight loss, or may be asympto... --- Walk 6 --- [FA9Z] Inflammation of spine, unspecified --PARENT--> [?] Inflammation of spine --CHILD--> [FA90] Infection of vertebra Def: A condition of the vertebrae, caused by an infection with a bacterial, viral, fungal, or parasitic source. This condition commonly presents with fever, chills, headache, weight loss, or may be asympto...	[ "[FB1Z] Conditions associated with the spine, unspecified\n --PARENT--> [?] Conditions associated with the spine\n Def: This is a group of conditions in which there is a deviation from or interruption of the normal structure or function of the spine....\n --RELATED_TO--> [?] Neck syndrome", "[FB1Z] Conditions associated with the spine, unspecified\n --PARENT--> [?] Conditions associated with the spine\n Def: This is a group of conditions in which there is a deviation from or interruption of the normal structure or function of the spine....\n --CHILD--> [?] Structural disorders of spine", "[FA7Z] Structural disorders of spine, unspecified\n --PARENT--> [?] Structural disorders of spine\n --CHILD--> [FA70] Spinal deformities", "[FA7Z] Structural disorders of spine, unspecified\n --PARENT--> [?] Structural disorders of spine\n --CHILD--> [FA71] Torticollis", "[FA9Z] Inflammation of spine, unspecified\n --PARENT--> [?] Inflammation of spine\n --CHILD--> [FA90] Infection of vertebra\n Def: A condition of the vertebrae, caused by an infection with a bacterial, viral, fungal, or parasitic source. This condition commonly presents with fever, chills, headache, weight loss, or may be asympto...", "[FA9Z] Inflammation of spine, unspecified\n --PARENT--> [?] Inflammation of spine\n --CHILD--> [FA90] Infection of vertebra\n Def: A condition of the vertebrae, caused by an infection with a bacterial, viral, fungal, or parasitic source. This condition commonly presents with fever, chills, headache, weight loss, or may be asympto..." ]	FB1Z	Conditions associated with the spine, unspecified	[ { "from_icd11": "FB1Z", "icd10_code": "M435X2", "icd10_title": "Other recurrent vertebral dislocation, cervical region" }, { "from_icd11": "FB1Z", "icd10_code": "M438X4", "icd10_title": "Other specified deforming dorsopathies, thoracic region" }, { "from_icd11": "FB1Z", "icd10_code": "M4324", "icd10_title": "Fusion of spine, thoracic region" }, { "from_icd11": "FB1Z", "icd10_code": "M4325", "icd10_title": "Fusion of spine, thoracolumbar region" }, { "from_icd11": "FB1Z", "icd10_code": "M438X6", "icd10_title": "Other specified deforming dorsopathies, lumbar region" }, { "from_icd11": "FB1Z", "icd10_code": "M4320", "icd10_title": "Fusion of spine, site unspecified" }, { "from_icd11": "FB1Z", "icd10_code": "M438X7", "icd10_title": "Other specified deforming dorsopathies, lumbosacral region" }, { "from_icd11": "FB1Z", "icd10_code": "M438X5", "icd10_title": "Other specified deforming dorsopathies, thoracolumbar region" }, { "from_icd11": "FB1Z", "icd10_code": "M4326", "icd10_title": "Fusion of spine, lumbar region" }, { "from_icd11": "FB1Z", "icd10_code": "M438X2", "icd10_title": "Other specified deforming dorsopathies, cervical region" }, { "from_icd11": "FB1Z", "icd10_code": "M4327", "icd10_title": "Fusion of spine, lumbosacral region" }, { "from_icd11": "FB1Z", "icd10_code": "M4322", "icd10_title": "Fusion of spine, cervical region" }, { "from_icd11": "FB1Z", "icd10_code": "M4321", "icd10_title": "Fusion of spine, occipito-atlanto-axial region" }, { "from_icd11": "FB1Z", "icd10_code": "M438X9", "icd10_title": "Other specified deforming dorsopathies, site unspecified" }, { "from_icd11": "FB1Z", "icd10_code": "M4328", "icd10_title": "Fusion of spine, sacral and sacrococcygeal region" } ]	M435X2	Other recurrent vertebral dislocation, cervical region
Access to the abdominal cavity and placement of the laparoscopic portals were performed as described above for the cadaveric study. Laparoscopic examination confirmed the presence of an indirect IH in the left inguinal canal, with a very enlarged IIR. The hernia could be reduced with the combination of external manipulation, laparoscopic atraumatic grasping traction (Endo Clinch II and/or Endo Lung, Covidien), Trendelenburg position and capnoperitoneum ( Supplementary Materials, Video S3 ). The LAPS of the left (herniated) IIR was carried out similarly to that described in the cadaveric study by combining both NSLT and the EndoClose device . Due to the large size of the IIR, three U-suture stitches were necessary for adequate partial closure of IIR. After knotting the percutaneous suture loops in the subcutaneous space, the skin was sutured with monofilar 2/0 USP glycinate in a simple interrupted pattern. The contralateral inguinal ring showed no signs of herniation, but a single percutaneous U-suture was performed using the same method as prophylaxis ( Supplementary Materials, Video S4 ). There were no surgical complications other than a slight tear of the peritoneum adjacent to the IIR that occurred during the manipulations, which did not receive further intervention. The ram recovered from anesthesia without complication. The durations of anesthesia and surgery were 115 and 90 min, respectively.	3.994141	0.604492	sec[2]/sec[1]/sec[0]/p[2]	en	0.999998	PMC10000226	https://doi.org/10.3390/ani13050836	[ "laparoscopic", "suture", "cadaveric", "inguinal", "endo", "supplementary", "materials", "video", "that", "percutaneous" ]	[ { "code": "PK9B.0", "title": "General or plastic surgery devices associated with injury or harm, diagnostic or monitoring devices" }, { "code": "PK9B.1", "title": "General or plastic surgery devices associated with injury or harm, therapeutic, nonsurgical or rehabilitative devices" }, { "code": "QB85", "title": "Attention to surgical dressings, drains or sutures" }, { "code": "EH93.1", "title": "Foreign body reaction to inorganic matter in the skin" }, { "code": "JA84.3", "title": "Maternal care for cervical incompetence" }, { "code": "PK9C.31", "title": "Mechanical complication of permanent sutures" }, { "code": "LB70.0Z", "title": "Craniosynostosis, unspecified" }, { "code": "QB42", "title": "Dependence on renal dialysis" }, { "code": "NB51.Z&XA3KX0", "title": "Open wound of groin" }, { "code": "NB50.Y", "title": "Other specified superficial injury of abdomen, lower back or pelvis" } ]	=== ICD-11 CODES FOUND === [PK9B.0] General or plastic surgery devices associated with injury or harm, diagnostic or monitoring devices Also known as: General or plastic surgery devices associated with injury or harm, diagnostic or monitoring devices \| General or plastic surgery devices associated with injury or harm, diagnostic laparoscopic equipment \| General or plastic surgery devices associated with injury or harm, needle biopsy equipment \| General or plastic surgery devices associated with injury or harm, skin biopsy equipment Excludes: Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm [PK9B.1] General or plastic surgery devices associated with injury or harm, therapeutic, nonsurgical or rehabilitative devices Definition: A general- or plastic-surgery device was involved in an adverse incident that occurred in a therapeutic (nonsurgical) and rehabilitative task Also known as: General or plastic surgery devices associated with injury or harm, therapeutic, nonsurgical or rehabilitative devices \| General or plastic surgery devices associated with adverse incidents, botox injection equipment \| General or plastic surgery devices associated with adverse incidents, therapeutic laparoscopic equipment Excludes: Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm [QB85] Attention to surgical dressings, drains or sutures Also known as: Attention to surgical dressings, drains or sutures \| Change of dressing \| Change of suture \| Removal of drain \| Removal of dressing [EH93.1] Foreign body reaction to inorganic matter in the skin Definition: A usually granulomatous, often sarcoidal reaction to the presence in the skin of inorganic foreign material which cannot be degraded or eliminated. Responsible agents include tattoo pigment, suture materials, silica, zirconium, aluminium, paraffin, and silicone. Also known as: Foreign body reaction to inorganic matter in the skin \| Silica granuloma \| Foreign body granuloma due to silica \| Talc granuloma \| Cutaneous suture granuloma [JA84.3] Maternal care for cervical incompetence Also known as: Maternal care for cervical incompetence \| maternal care for cervical incompetence, unspecified trimester \| maternal care for cervical insufficiency \| cervical incompetence in pregnancy \| Maternal care for cerclage with or without mention of cervical incompetence [PK9C.31] Mechanical complication of permanent sutures Also known as: Mechanical complication of permanent sutures [LB70.0Z] Craniosynostosis, unspecified Also known as: Craniosynostosis, unspecified \| Craniosynostosis \| congenital ossification of cranial sutures \| congenital ossification of sutures of skull \| craniostenosis [QB42] Dependence on renal dialysis Also known as: Dependence on renal dialysis \| renal dialysis status \| presence of arteriovenous shunt for dialysis \| dependence on haemodialysis \| Dependence on renal dialysis, acute haemodialysis Includes: renal dialysis status Excludes: dialysis preparation, treatment or session [NB50.Y] Other specified superficial injury of abdomen, lower back or pelvis Also known as: Other specified superficial injury of abdomen, lower back or pelvis \| Haematoma of abdominal wall \| Buttock haematoma \| Flank haematoma \| Groin haematoma === GRAPH WALKS === --- Walk 1 --- [PK9B.0] General or plastic surgery devices associated with injury or harm, diagnostic or monitoring devices --EXCLUDES--> [?] Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm --CHILD--> [?] Structural device failure without injury or harm Def: Mechanical or material device failure not related to the installation of the device without any documented injury or harm.... --- Walk 2 --- [PK9B.0] General or plastic surgery devices associated with injury or harm, diagnostic or monitoring devices --EXCLUDES--> [?] Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm --CHILD--> [?] Dislodgement, misconnection or de-attachment of a surgical or medical device without injury or harm Def: A device that has moved out of place, become disconnected, loosened or unstable, but without documented injury or harm.... --- Walk 3 --- [PK9B.1] General or plastic surgery devices associated with injury or harm, therapeutic, nonsurgical or rehabilitative devices Def: A general- or plastic-surgery device was involved in an adverse incident that occurred in a therapeutic (nonsurgical) and rehabilitative task... --EXCLUDES--> [?] Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm --EXCLUDES--> [?] Mode of injury or harm associated with a surgical or other medical device, implant or graft --- Walk 4 --- [PK9B.1] General or plastic surgery devices associated with injury or harm, therapeutic, nonsurgical or rehabilitative devices Def: A general- or plastic-surgery device was involved in an adverse incident that occurred in a therapeutic (nonsurgical) and rehabilitative task... --PARENT--> [PK9B] General or plastic surgery devices, implants or grafts associated with injury or harm --CHILD--> [PK9B.0] General or plastic surgery devices associated with injury or harm, diagnostic or monitoring devices --- Walk 5 --- [QB85] Attention to surgical dressings, drains or sutures --PARENT--> [?] Contact with health services for specific surgical interventions --CHILD--> [QB82] Contact with health services for routine or ritual circumcision --- Walk 6 --- [QB85] Attention to surgical dressings, drains or sutures --PARENT--> [?] Contact with health services for specific surgical interventions --EXCLUDES--> [?] Contact with health services for purposes of examination or investigation	[ "[PK9B.0] General or plastic surgery devices associated with injury or harm, diagnostic or monitoring devices\n --EXCLUDES--> [?] Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm\n --CHILD--> [?] Structural device failure without injury or harm\n Def: Mechanical or material device failure not related to the installation of the device without any documented injury or harm....", "[PK9B.0] General or plastic surgery devices associated with injury or harm, diagnostic or monitoring devices\n --EXCLUDES--> [?] Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm\n --CHILD--> [?] Dislodgement, misconnection or de-attachment of a surgical or medical device without injury or harm\n Def: A device that has moved out of place, become disconnected, loosened or unstable, but without documented injury or harm....", "[PK9B.1] General or plastic surgery devices associated with injury or harm, therapeutic, nonsurgical or rehabilitative devices\n Def: A general- or plastic-surgery device was involved in an adverse incident that occurred in a therapeutic (nonsurgical) and rehabilitative task...\n --EXCLUDES--> [?] Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm\n --EXCLUDES--> [?] Mode of injury or harm associated with a surgical or other medical device, implant or graft", "[PK9B.1] General or plastic surgery devices associated with injury or harm, therapeutic, nonsurgical or rehabilitative devices\n Def: A general- or plastic-surgery device was involved in an adverse incident that occurred in a therapeutic (nonsurgical) and rehabilitative task...\n --PARENT--> [PK9B] General or plastic surgery devices, implants or grafts associated with injury or harm\n --CHILD--> [PK9B.0] General or plastic surgery devices associated with injury or harm, diagnostic or monitoring devices", "[QB85] Attention to surgical dressings, drains or sutures\n --PARENT--> [?] Contact with health services for specific surgical interventions\n --CHILD--> [QB82] Contact with health services for routine or ritual circumcision", "[QB85] Attention to surgical dressings, drains or sutures\n --PARENT--> [?] Contact with health services for specific surgical interventions\n --EXCLUDES--> [?] Contact with health services for purposes of examination or investigation" ]	PK9B.0	General or plastic surgery devices associated with injury or harm, diagnostic or monitoring devices	[ { "from_icd11": "PK9B.0", "icd10_code": "Y810", "icd10_title": "Diagnostic and monitoring general- and plastic-surgery devices associated with adverse incidents" }, { "from_icd11": "PK9B.1", "icd10_code": "Y811", "icd10_title": "Therapeutic (nonsurgical) and rehabilitative general- and plastic-surgery devices associated with adverse incidents" }, { "from_icd11": "QB85", "icd10_code": "Z481", "icd10_title": "Encounter for planned postprocedural wound closure" }, { "from_icd11": "QB85", "icd10_code": "Z4821", "icd10_title": "Encounter for aftercare following heart transplant" }, { "from_icd11": "QB85", "icd10_code": "Z483", "icd10_title": "Aftercare following surgery for neoplasm" }, { "from_icd11": "QB85", "icd10_code": "Z4823", "icd10_title": "Encounter for aftercare following liver transplant" }, { "from_icd11": "QB85", "icd10_code": "Z4822", "icd10_title": "Encounter for aftercare following kidney transplant" }, { "from_icd11": "QB85", "icd10_code": "Z48298", "icd10_title": "Encounter for aftercare following other organ transplant" }, { "from_icd11": "QB85", "icd10_code": "Z4802", "icd10_title": "Encounter for removal of sutures" }, { "from_icd11": "QB85", "icd10_code": "Z4803", "icd10_title": "Encounter for change or removal of drains" }, { "from_icd11": "QB85", "icd10_code": "Z4801", "icd10_title": "Encounter for change or removal of surgical wound dressing" }, { "from_icd11": "QB85", "icd10_code": "Z4800", "icd10_title": "Encounter for change or removal of nonsurgical wound dressing" }, { "from_icd11": "QB85", "icd10_code": "Z48", "icd10_title": "Encounter for other postprocedural aftercare" }, { "from_icd11": "QB85", "icd10_code": "Z480", "icd10_title": "Encounter for attention to dressings, sutures and drains" }, { "from_icd11": "EH93.1", "icd10_code": "L923", "icd10_title": "Foreign body granuloma of the skin and subcutaneous tissue" } ]	Y810	Diagnostic and monitoring general- and plastic-surgery devices associated with adverse incidents
It is plausible that delayed ipsilateral kidney atrophy following lateral lumbar surgery may be attributed to potential factors such as indirect compression or vascular changes impeding renal blood flow, as well as the possibility of nerve injury or disruption affecting kidney perfusion. It is recommended that surgical approaches minimize tissue retraction and optimize instrument placement to reduce the risk of indirect compression, ensure careful preservation of renal blood supply, and employ meticulous techniques to minimize nerve injury or disruption during lateral lumbar surgery, considering the potential role of these factors in preventing delayed ipsilateral kidney atrophy. If such a complication arises, appropriate management should involve prompt recognition and tailored treatment approaches, including relieving indirect compression if present, restoring renal blood flow in cases of vascular changes, and implementing strategies for nerve regeneration and pain management if nerve injury is implicated, with multidisciplinary collaboration being essential for optimal patient care. In our case, no direct injury to the kidney was observed intraoperatively, nor injury to the ureter or renal vessels that could explain the renal atrophy, and therefore the etiology remains elusive, highlighting the need for further research into these mechanisms to deepen our understanding of this rare complication.	4.175781	0.581055	sec[2]/p[3]	en	0.999997	PMC10423007	https://doi.org/10.7759/cureus.41818	[ "renal", "injury", "kidney", "nerve", "that", "atrophy", "indirect", "compression", "blood", "ipsilateral" ]	[ { "code": "GC2Z&XA6KU8", "title": "Disease of kidney, not elsewhere classified" }, { "code": "GB6Z", "title": "Kidney failure, unspecified" }, { "code": "LB30.1", "title": "Renal dysplasia" }, { "code": "NB92.0Y", "title": "Other specified injury of kidney" }, { "code": "LB30.7", "title": "Ectopic or pelvic kidney" }, { "code": "ND56.Z", "title": "Unspecified injury to unspecified part of trunk, limb or body region" }, { "code": "ND37", "title": "Unspecified multiple injuries" }, { "code": "NB91.Y&XA9607", "title": "Injury of intestine" }, { "code": "ND56.4", "title": "Injury of nerve of unspecified body region" }, { "code": "NF0A.Z", "title": "Early complications of trauma, not elsewhere classified" } ]	=== ICD-11 CODES FOUND === [GB6Z] Kidney failure, unspecified Also known as: Kidney failure, unspecified \| nontraumatic kidney injury \| renal failure NOS \| kidney block \| renal impairment NOS [LB30.1] Renal dysplasia Definition: A condition characterised by abnormal development of one or both kidneys. Also known as: Renal dysplasia \| congenital renal dysplasia \| dysplasia of kidney \| dysplastic kidney \| Primary renal dysplasia Excludes: Autosomal dominant polycystic kidney disease [NB92.0Y] Other specified injury of kidney Also known as: Other specified injury of kidney \| Injury of kidney without open wound into cavity \| Injury of kidney with open wound into cavity \| Haematoma of kidney \| traumatic perirenal haematoma [LB30.7] Ectopic or pelvic kidney Definition: A birth defect characterised by an abnormally positioned kidney; may be asymptomatic or result in urine blockage, infection or kidney stones Also known as: Ectopic or pelvic kidney \| Congenital displaced kidney \| congenital misplaced kidney \| congenital malposition of kidney \| congenital prolapsed kidney Includes: Congenital displaced kidney \| Malrotation of kidney [ND56.Z] Unspecified injury to unspecified part of trunk, limb or body region Also known as: Unspecified injury to unspecified part of trunk, limb or body region \| Injury of unspecified body region \| injury NOS \| trauma NOS \| traumatic injury NOS [ND37] Unspecified multiple injuries Also known as: Unspecified multiple injuries \| multiple trauma NOS \| multiple traumatic injuries \| multiple sites of injury \| multiple system injury Excludes: injury NOS [ND56.4] Injury of nerve of unspecified body region Also known as: Injury of nerve of unspecified body region \| injuries to nerves, nerve plexuses and roots \| injury to nerves, unspecified site \| nerve damage NOS \| Injury of nerve NOS Excludes: multiple injuries of nerves NOS [NF0A.Z] Early complications of trauma, not elsewhere classified Also known as: Early complications of trauma, not elsewhere classified \| Certain early complications of trauma, not elsewhere classified \| early trauma complications \| early complication of trauma \| trauma complications === GRAPH WALKS === --- Walk 1 --- [GB6Z] Kidney failure, unspecified --PARENT--> [?] Kidney failure Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ... --RELATED_TO--> [?] Renal failure following abortion, ectopic or molar pregnancy --- Walk 2 --- [GB6Z] Kidney failure, unspecified --PARENT--> [?] Kidney failure Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ... --CHILD--> [GB6Z] Kidney failure, unspecified --- Walk 3 --- [LB30.1] Renal dysplasia Def: A condition characterised by abnormal development of one or both kidneys.... --EXCLUDES--> [?] Autosomal dominant polycystic kidney disease Def: Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and d... --PARENT--> [?] Chronic tubulo-interstitial nephritis associated with familial or genetic diseases --- Walk 4 --- [LB30.1] Renal dysplasia Def: A condition characterised by abnormal development of one or both kidneys.... --EXCLUDES--> [?] Autosomal dominant polycystic kidney disease Def: Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and d... --CHILD--> [?] Autosomal dominant polycystic kidney disease type 1 without tuberous sclerosis Def: Autosomal dominant polycystic kidney disease due to mutations on Polycystin1 gene on chromosome 16 (PKD1 gene)... --- Walk 5 --- [NB92.0Y] Other specified injury of kidney --PARENT--> [NB92.0] Injury of kidney --CHILD--> [NB92.02] Laceration of kidney, minor --- Walk 6 --- [NB92.0Y] Other specified injury of kidney --PARENT--> [NB92.0] Injury of kidney --CHILD--> [NB92.01] Contusion of kidney, major	[ "[GB6Z] Kidney failure, unspecified\n --PARENT--> [?] Kidney failure\n Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ...\n --RELATED_TO--> [?] Renal failure following abortion, ectopic or molar pregnancy", "[GB6Z] Kidney failure, unspecified\n --PARENT--> [?] Kidney failure\n Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ...\n --CHILD--> [GB6Z] Kidney failure, unspecified", "[LB30.1] Renal dysplasia\n Def: A condition characterised by abnormal development of one or both kidneys....\n --EXCLUDES--> [?] Autosomal dominant polycystic kidney disease\n Def: Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and d...\n --PARENT--> [?] Chronic tubulo-interstitial nephritis associated with familial or genetic diseases", "[LB30.1] Renal dysplasia\n Def: A condition characterised by abnormal development of one or both kidneys....\n --EXCLUDES--> [?] Autosomal dominant polycystic kidney disease\n Def: Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and d...\n --CHILD--> [?] Autosomal dominant polycystic kidney disease type 1 without tuberous sclerosis\n Def: Autosomal dominant polycystic kidney disease due to mutations on Polycystin1 gene on chromosome 16 (PKD1 gene)...", "[NB92.0Y] Other specified injury of kidney\n --PARENT--> [NB92.0] Injury of kidney\n --CHILD--> [NB92.02] Laceration of kidney, minor", "[NB92.0Y] Other specified injury of kidney\n --PARENT--> [NB92.0] Injury of kidney\n --CHILD--> [NB92.01] Contusion of kidney, major" ]	GC2Z&XA6KU8	Disease of kidney, not elsewhere classified	[ { "from_icd11": "GB6Z", "icd10_code": "N19", "icd10_title": "Unspecified kidney failure" }, { "from_icd11": "GB6Z", "icd10_code": "N17-N19", "icd10_title": "" }, { "from_icd11": "GB6Z", "icd10_code": "N17", "icd10_title": "Acute kidney failure" }, { "from_icd11": "LB30.1", "icd10_code": "Q614", "icd10_title": "Renal dysplasia" }, { "from_icd11": "LB30.7", "icd10_code": "Q632", "icd10_title": "Ectopic kidney" }, { "from_icd11": "LB30.7", "icd10_code": "Q63", "icd10_title": "Other congenital malformations of kidney" }, { "from_icd11": "ND56.Z", "icd10_code": "T1491XA", "icd10_title": "Suicide attempt, initial encounter" }, { "from_icd11": "ND56.Z", "icd10_code": "T1490XS", "icd10_title": "Injury, unspecified, sequela" }, { "from_icd11": "ND56.Z", "icd10_code": "T1490", "icd10_title": "Injury, unspecified" }, { "from_icd11": "ND56.Z", "icd10_code": "T1491", "icd10_title": "Suicide attempt" }, { "from_icd11": "ND56.Z", "icd10_code": "T1490XA", "icd10_title": "Injury, unspecified, initial encounter" }, { "from_icd11": "ND56.Z", "icd10_code": "T148XXS", "icd10_title": "Other injury of unspecified body region, sequela" }, { "from_icd11": "ND56.Z", "icd10_code": "T148XXD", "icd10_title": "Other injury of unspecified body region, subsequent encounter" }, { "from_icd11": "ND56.Z", "icd10_code": "T148", "icd10_title": "Other injury of unspecified body region" }, { "from_icd11": "ND56.Z", "icd10_code": "T14", "icd10_title": "Injury of unspecified body region" } ]	N19	Unspecified kidney failure
An 18-year-old woman, brown, single, peasant. She started the regimen I treatment in 2003, and abandoned it. One year later, the treatment was resumed with the enhanced scheme I, showing therapeutic failure. One year later, the MDR-TB treatment began. Two years later, the patient was treated for MDR-X tuberculosis. Bacilloscopy oscillated during the course of treatment. The culture trials conducted during treatment were positive for M. tuberculosis , showing a resistance to isoniazid, rifampicin and ethambutol. Six months later, a chest radiograph showed alveolar infiltrates in the left lung base. A year and 10 months later, the radiograph showed left lung parenchymal destruction, with cavitary lesions in the right upper lobe (Table 1 ). Table 1 Clinical characteristics of patients with documented multidrug-resistant tuberculosis (MDR-TB) Patient Age Tuberculosis duration, years Drugs to which the patient was resistant a Severe CXR findings b Time to smear conversion, months Adverse reactions to the treatment 1 33 3 INH, Rif, Eth, Stm No 12 None 2 27 5 INH, Rif Yes – GI 3 38 4 INH, Rif Yes – None 4 18 7 INH, Rif, Eth Yes – None CXR chest radiograph, Eth ethambutol, INH isoniazid, Rif rifampin, Stm streptomycin, GI gastrointestinal a Patients were tested for resistance to Eth, INH, Rif, PZA, Stm, Km, Cm, and Tha, as well as resistance to ciprofloxacin and cycloserine b Cavitary and bilateral lesions	3.935547	0.858887	sec[1]/sec[3]/p[0]	en	0.999996	27145827	https://doi.org/10.1186/s13104-016-2063-x	[ "tuberculosis", "resistance", "radiograph", "none", "isoniazid", "ethambutol", "chest", "lung", "cavitary", "lesions" ]	[ { "code": "1B1Z", "title": "Tuberculosis, unspecified" }, { "code": "1B1Y", "title": "Other specified tuberculosis" }, { "code": "KA61.0", "title": "Congenital tuberculosis" }, { "code": "1B12.40", "title": "Tuberculosis of bones or joints" }, { "code": "1B10.Z", "title": "Respiratory tuberculosis, without mention of bacteriological or histological confirmation" }, { "code": "MG55.0", "title": "Artemisinin resistant Plasmodium falciparum" }, { "code": "5A74.Y", "title": "Other specified adrenocortical insufficiency" }, { "code": "5A44", "title": "Insulin-resistance syndromes" }, { "code": "LD2A.4", "title": "46,XY disorder of sex development due to androgen resistance" }, { "code": "LB45.1", "title": "46,XX gonadal dysgenesis" } ]	=== ICD-11 CODES FOUND === [1B1Z] Tuberculosis, unspecified Also known as: Tuberculosis, unspecified \| Infections due to Mycobacterium tuberculosis and Mycobacterium bovis \| TB - [tuberculosis] \| Tuberculosis infection \| TBC - [tuberculosis] [1B1Y] Other specified tuberculosis Also known as: Other specified tuberculosis \| Disorders of kidney or ureter in tuberculosis [KA61.0] Congenital tuberculosis Definition: A disease affecting infants, caused by an infection with the bacteria Mycobacterium tuberculosis in utero. Transmission is by vertical transmission. Also known as: Congenital tuberculosis \| congenital tuberculous gangrene \| congenital tuberculous degeneration \| congenital necrotic tuberculosis \| congenital tuberculous infection [1B12.40] Tuberculosis of bones or joints Definition: A disease of the bones and joints, caused by an infection with the bacteria Mycobacterium tuberculosis. This disease commonly presents with bone pain, joint inflammation, loss of movement or feeling in the affected bone or joint, and weak bones prone to fracture. Transmission is through haematogenous spread to the bones and joints after inhalation of infected respiratory secretions. Confirmation is by identification of Mycobacterium tuberculosis in biopsy samples of the affected site. Also known as: Tuberculosis of bones or joints \| tuberculous cartilage \| tuberculosis of bone \| tuberculosis of joint \| tuberculous bone [1B10.Z] Respiratory tuberculosis, without mention of bacteriological or histological confirmation Also known as: Respiratory tuberculosis, without mention of bacteriological or histological confirmation \| Tuberculosis of the respiratory system \| respiratory tuberculosis \| pulmonary tuberculosis \| pulmonary TB [MG55.0] Artemisinin resistant Plasmodium falciparum Also known as: Artemisinin resistant Plasmodium falciparum \| Antimicrobial resistant Plasmodium falciparum \| multidrug-resistant falciparum malaria \| artesunate monotherapy resistance \| ACT - [artemisinin-based combination therapy] resistance [5A74.Y] Other specified adrenocortical insufficiency Also known as: Other specified adrenocortical insufficiency \| Congenital adrenocortical insufficiency \| Congenital isolated ACTH deficiency \| Familial adrenal hypoplasia \| Familial hypoadrenocorticism [5A44] Insulin-resistance syndromes Also known as: Insulin-resistance syndromes \| Insulin-resistance syndrome type A \| Insulin-resistance syndrome type B \| Rabson-Mendenhall syndrome \| Laminopathy type Decaudain-Vigouroux [LD2A.4] 46,XY disorder of sex development due to androgen resistance Definition: Androgen insensitivity syndrome (AIS) is a disorder of sex development (DSD) characterised by the presence of female external genitalia, ambiguous genitalia or variable defects in virilization in a 46,XY individual with absent or partial responsiveness to age-appropriate levels of androgens. It comprises two clinical subgroups: complete AIS (CAIS) and partial AIS (PAIS). Also known as: 46,XY disorder of sex development due to androgen resistance \| Androgen resistance syndrome \| Testicular feminization syndrome \| Androgen insensitivity syndrome \| Goldberg-Maxwell syndrome [LB45.1] 46,XX gonadal dysgenesis Definition: Karyotype 46 XX; Gonads: gonadal dysgenesis (streak gonads); Phenotype female with symptoms like primary amenorrhea, hypergonadotropic hypogonadism, normal stature and no other abnormalities. Also known as: 46,XX gonadal dysgenesis \| Follicular stimulating hormone-resistant ovaries \| Resistant ovary syndrome \| 46,XX pure gonadal dysgenesis \| 46,XX complete gonadal dysgenesis === GRAPH WALKS === --- Walk 1 --- [1B1Z] Tuberculosis, unspecified --PARENT--> [?] Tuberculosis Def: A disease caused by an infection with bacteria of the Mycobacterium tuberculosis complex. This disease presents with symptoms depending on the site of infection. Transmission is commonly by inhalation... --RELATED_TO--> [?] Congenital tuberculosis Def: A disease affecting infants, caused by an infection with the bacteria Mycobacterium tuberculosis in utero. Transmission is by vertical transmission.... --- Walk 2 --- [1B1Z] Tuberculosis, unspecified --PARENT--> [?] Tuberculosis Def: A disease caused by an infection with bacteria of the Mycobacterium tuberculosis complex. This disease presents with symptoms depending on the site of infection. Transmission is commonly by inhalation... --RELATED_TO--> [?] Congenital tuberculosis Def: A disease affecting infants, caused by an infection with the bacteria Mycobacterium tuberculosis in utero. Transmission is by vertical transmission.... --- Walk 3 --- [1B1Y] Other specified tuberculosis --PARENT--> [?] Tuberculosis Def: A disease caused by an infection with bacteria of the Mycobacterium tuberculosis complex. This disease presents with symptoms depending on the site of infection. Transmission is commonly by inhalation... --RELATED_TO--> [?] HIV disease clinical stage 1 associated with tuberculosis --- Walk 4 --- [1B1Y] Other specified tuberculosis --PARENT--> [?] Tuberculosis Def: A disease caused by an infection with bacteria of the Mycobacterium tuberculosis complex. This disease presents with symptoms depending on the site of infection. Transmission is commonly by inhalation... --EXCLUDES--> [?] Pneumoconiosis associated with tuberculosis Def: This is an occupational lung disease and a restrictive lung disease caused by the inhalation of dust, often in mines, associated with a common, and in many cases lethal, infectious disease caused by v... --- Walk 5 --- [KA61.0] Congenital tuberculosis Def: A disease affecting infants, caused by an infection with the bacteria Mycobacterium tuberculosis in utero. Transmission is by vertical transmission.... --PARENT--> [KA61] Other bacterial infections of the fetus or newborn --RELATED_TO--> [?] Early congenital syphilis, symptomatic Def: A disease affecting newborns or children up to 2 years of age, caused by an infection with the gram-negative bacteria Treponema pallidum pallidum in utero. This disease is characterised by premature b... --- Walk 6 --- [KA61.0] Congenital tuberculosis Def: A disease affecting infants, caused by an infection with the bacteria Mycobacterium tuberculosis in utero. Transmission is by vertical transmission.... --PARENT--> [KA61] Other bacterial infections of the fetus or newborn --RELATED_TO--> [?] Neonatal necrotising fasciitis Def: Neonatal necrotising fasciitis is a life-threatening acute necrotising infection of fascia, subcutaneous tissues, and overlying skin similar to the condition seen in adults. It is rare in neonates but...	[ "[1B1Z] Tuberculosis, unspecified\n --PARENT--> [?] Tuberculosis\n Def: A disease caused by an infection with bacteria of the Mycobacterium tuberculosis complex. This disease presents with symptoms depending on the site of infection. Transmission is commonly by inhalation...\n --RELATED_TO--> [?] Congenital tuberculosis\n Def: A disease affecting infants, caused by an infection with the bacteria Mycobacterium tuberculosis in utero. Transmission is by vertical transmission....", "[1B1Z] Tuberculosis, unspecified\n --PARENT--> [?] Tuberculosis\n Def: A disease caused by an infection with bacteria of the Mycobacterium tuberculosis complex. This disease presents with symptoms depending on the site of infection. Transmission is commonly by inhalation...\n --RELATED_TO--> [?] Congenital tuberculosis\n Def: A disease affecting infants, caused by an infection with the bacteria Mycobacterium tuberculosis in utero. Transmission is by vertical transmission....", "[1B1Y] Other specified tuberculosis\n --PARENT--> [?] Tuberculosis\n Def: A disease caused by an infection with bacteria of the Mycobacterium tuberculosis complex. This disease presents with symptoms depending on the site of infection. Transmission is commonly by inhalation...\n --RELATED_TO--> [?] HIV disease clinical stage 1 associated with tuberculosis", "[1B1Y] Other specified tuberculosis\n --PARENT--> [?] Tuberculosis\n Def: A disease caused by an infection with bacteria of the Mycobacterium tuberculosis complex. This disease presents with symptoms depending on the site of infection. Transmission is commonly by inhalation...\n --EXCLUDES--> [?] Pneumoconiosis associated with tuberculosis\n Def: This is an occupational lung disease and a restrictive lung disease caused by the inhalation of dust, often in mines, associated with a common, and in many cases lethal, infectious disease caused by v...", "[KA61.0] Congenital tuberculosis\n Def: A disease affecting infants, caused by an infection with the bacteria Mycobacterium tuberculosis in utero. Transmission is by vertical transmission....\n --PARENT--> [KA61] Other bacterial infections of the fetus or newborn\n --RELATED_TO--> [?] Early congenital syphilis, symptomatic\n Def: A disease affecting newborns or children up to 2 years of age, caused by an infection with the gram-negative bacteria Treponema pallidum pallidum in utero. This disease is characterised by premature b...", "[KA61.0] Congenital tuberculosis\n Def: A disease affecting infants, caused by an infection with the bacteria Mycobacterium tuberculosis in utero. Transmission is by vertical transmission....\n --PARENT--> [KA61] Other bacterial infections of the fetus or newborn\n --RELATED_TO--> [?] Neonatal necrotising fasciitis\n Def: Neonatal necrotising fasciitis is a life-threatening acute necrotising infection of fascia, subcutaneous tissues, and overlying skin similar to the condition seen in adults. It is rare in neonates but..." ]	1B1Z	Tuberculosis, unspecified	[ { "from_icd11": "1B1Z", "icd10_code": "A15-A19", "icd10_title": "" }, { "from_icd11": "KA61.0", "icd10_code": "P370", "icd10_title": "Congenital tuberculosis" }, { "from_icd11": "1B12.40", "icd10_code": "A1801", "icd10_title": "Tuberculosis of spine" }, { "from_icd11": "1B12.40", "icd10_code": "A1802", "icd10_title": "Tuberculous arthritis of other joints" }, { "from_icd11": "1B12.40", "icd10_code": "A180", "icd10_title": "Tuberculosis of bones and joints" }, { "from_icd11": "1B12.40", "icd10_code": "M90", "icd10_title": "Osteopathies in diseases classified elsewhere" }, { "from_icd11": "1B12.40", "icd10_code": "M900", "icd10_title": "" }, { "from_icd11": "1B10.Z", "icd10_code": "A162", "icd10_title": "" }, { "from_icd11": "1B10.Z", "icd10_code": "A163", "icd10_title": "" }, { "from_icd11": "1B10.Z", "icd10_code": "A164", "icd10_title": "" }, { "from_icd11": "1B10.Z", "icd10_code": "A165", "icd10_title": "" }, { "from_icd11": "1B10.Z", "icd10_code": "A167", "icd10_title": "" }, { "from_icd11": "1B10.Z", "icd10_code": "A168", "icd10_title": "" }, { "from_icd11": "1B10.Z", "icd10_code": "A169", "icd10_title": "" }, { "from_icd11": "5A44", "icd10_code": "E10-E14", "icd10_title": "" } ]	A15-A19
Fasting with total parental nutrition was indicated, and corticosteroid pulse therapy with methylprednisolone (1 g/day for 3 days) was initiated. After two courses of corticosteroid pulse therapy, the abdominal pain and hematochezia resolved. Blood testing showed improvement in inflammatory and fibrinolytic markers. One week after the dosage of corticosteroid was reduced to 20 mg/day, the abdominal pain recurred. Although there was no reactivation of oral and genital ulcers or exacerbation of the rashes, blood testing showed reelevation of CRP, FDP, and D-dimer levels. Because the clinical findings were corticosteroid-dependent, the patient was begun on adalimumab, a fully humanized anti-TNF- α monoclonal antibody. She received subcutaneous injections of adalimumab at a dose of 160 mg in week 0, 80 mg in week 2, and 40 mg every other week thereafter. The symptoms and clinical manifestations resolved soon after the initiation of adalimumab. The circulating inflammatory markers converted to negative. Initiation of the adalimumab made it possible to reduce the corticosteroid dose without any symptoms . Epithelialization of the ulcers was demonstrated on lower gastrointestinal endoscopy, which was performed 1 week after the initiation of adalimumab ( Figure 3(b) ). Although the oral corticosteroid dose was gradually decreased, the symptoms never recurred. No adverse effects of adalimumab were observed.	3.960938	0.96875	sec[1]/p[1]	en	0.999998	26609459	https://doi.org/10.1155/2015/716138	[ "corticosteroid", "adalimumab", "initiation", "pulse", "abdominal", "pain", "resolved", "blood", "testing", "inflammatory" ]	[ { "code": "EE40.32", "title": "Purpura or bruising due to vascular fragility" }, { "code": "EE40.0", "title": "Corticosteroid-induced skin atrophy" }, { "code": "9C61.2A", "title": "Glaucoma due to drugs" }, { "code": "EE40.1Y", "title": "Stretch marks of other specified aetiology" }, { "code": "NE60", "title": "Harmful effects of drugs, medicaments or biological substances, not elsewhere classified" }, { "code": "DA08.0&XA5R09", "title": "Caries limited to enamel" }, { "code": "4A00.10", "title": "Immunodeficiency with an early component of complement deficiency" }, { "code": "1C1D.0", "title": "Primary yaws" }, { "code": "1C23.0", "title": "Initial stage of trachoma" }, { "code": "NF0A.2", "title": "Traumatic secondary or recurrent haemorrhage, not elsewhere classified" } ]	=== ICD-11 CODES FOUND === [EE40.32] Purpura or bruising due to vascular fragility Definition: Purpura due to leakage or rupture of abnormally fragile cutaneous blood vessels. Also known as: Purpura or bruising due to vascular fragility \| Senile purpura \| Actinic purpura \| Corticosteroid-induced purpura \| Purpura or bruising due to genetically-determined skin fragility Includes: Senile purpura \| Corticosteroid-induced purpura \| Purpura or bruising due to genetically-determined skin fragility [EE40.0] Corticosteroid-induced skin atrophy Also known as: Corticosteroid-induced skin atrophy [9C61.2A] Glaucoma due to drugs Also known as: Glaucoma due to drugs \| Glaucoma secondary to drugs \| Corticosteroid-induced glaucoma \| corticosteroid glaucoma \| steroid-induced glaucoma [EE40.1Y] Stretch marks of other specified aetiology Also known as: Stretch marks of other specified aetiology \| Pubertal stretch marks \| Pubertal striae distensae \| Obesity-related stretch marks \| Striae distensae due to obesity [NE60] Harmful effects of drugs, medicaments or biological substances, not elsewhere classified Also known as: Harmful effects of drugs, medicaments or biological substances, not elsewhere classified \| drugs, medicaments or biological substances, toxicity not elsewhere classified \| adverse drug effects \| drug reaction NOS \| drug allergy NOS Excludes: Alcohol intoxication \| pathological drug intoxication \| hypersensitivity reaction to correctly administered drug [4A00.10] Immunodeficiency with an early component of complement deficiency Also known as: Immunodeficiency with an early component of complement deficiency \| Deficiency of complement initial pathway \| Complement component C1q deficiency \| Complement component C1r/C1s deficiency \| Complement component C2 deficiency [1C1D.0] Primary yaws Definition: Primary yaws results from primary inoculation of Treponema pallidum subsp. pertenue into the skin, manifesting 2-12 weeks later as a localised papule (initial, primary or ‘mother' yaw) before developing into a large non-tender ulcerating nodule, often resembling a raspberry (hence the name ‘framboesia’). The primary lesion is most commonly located on the legs and ankles may also be found on the buttocks, arms, hands, and face. It usually heals after 3–6 months and is still present at the onset o Also known as: Primary yaws \| Chancre of yaws \| Primary framboesia \| initial lesions of yaws \| mother yaw Includes: Chancre of yaws \| Primary framboesia [1C23.0] Initial stage of trachoma Definition: This refers to the initial stage of an infectious disease caused by the Chlamydia trachomatis bacterium which produces a characteristic roughening of the inner surface of the eyelids. Also known as: Initial stage of trachoma \| Trachoma dubium Includes: Trachoma dubium [NF0A.2] Traumatic secondary or recurrent haemorrhage, not elsewhere classified Also known as: Traumatic secondary or recurrent haemorrhage, not elsewhere classified \| secondary haemorrhage following initial haemorrhage at time of injury \| traumatic secondary or recurrent bleed === GRAPH WALKS === --- Walk 1 --- [EE40.32] Purpura or bruising due to vascular fragility Def: Purpura due to leakage or rupture of abnormally fragile cutaneous blood vessels.... --PARENT--> [EE40.3] Skin fragility Def: Fragility of the skin due principally to genetic or acquired abnormalities of dermal matrix proteins.... --CHILD--> [EE40.32] Purpura or bruising due to vascular fragility Def: Purpura due to leakage or rupture of abnormally fragile cutaneous blood vessels.... --- Walk 2 --- [EE40.32] Purpura or bruising due to vascular fragility Def: Purpura due to leakage or rupture of abnormally fragile cutaneous blood vessels.... --PARENT--> [EE40.3] Skin fragility Def: Fragility of the skin due principally to genetic or acquired abnormalities of dermal matrix proteins.... --EXCLUDES--> [?] Epidermal fragility Def: Epidermal fragility of unknown or unspecified cause resulting in reduced resistance to mechanical stress and manifesting as abnormal fissuring, erosion or blistering of the skin surface.... --- Walk 3 --- [EE40.0] Corticosteroid-induced skin atrophy --PARENT--> [EE40] Atrophy or degeneration of dermal or subcutaneous connective tissue Def: A heterogeneous group of disorders resulting from atrophic and degenerative changes in dermal and subcutaneous collagen and elastin.... --CHILD--> [EE40.1] Stretch marks Def: Linear scars attributable to rupture of the normal dermal matrix from distension by abnormal physical forces (pregnancy, obesity, pubertal growth spurt), increased collagenase activity (corticosteroid... --- Walk 4 --- [EE40.0] Corticosteroid-induced skin atrophy --PARENT--> [EE40] Atrophy or degeneration of dermal or subcutaneous connective tissue Def: A heterogeneous group of disorders resulting from atrophic and degenerative changes in dermal and subcutaneous collagen and elastin.... --PARENT--> [?] Disorders of cutaneous connective tissue Def: Skin disorders attributable to abnormalities affecting dermal and subcutaneous collagen, elastin and other connective tissue components.... --- Walk 5 --- [9C61.2A] Glaucoma due to drugs --PARENT--> [9C61.2] Secondary open-angle glaucoma --CHILD--> [9C61.22] Lens-induced secondary open-angle glaucoma --- Walk 6 --- [9C61.2A] Glaucoma due to drugs --PARENT--> [9C61.2] Secondary open-angle glaucoma --RELATED_TO--> [?] Glaucoma due to ocular surgery or laser	[ "[EE40.32] Purpura or bruising due to vascular fragility\n Def: Purpura due to leakage or rupture of abnormally fragile cutaneous blood vessels....\n --PARENT--> [EE40.3] Skin fragility\n Def: Fragility of the skin due principally to genetic or acquired abnormalities of dermal matrix proteins....\n --CHILD--> [EE40.32] Purpura or bruising due to vascular fragility\n Def: Purpura due to leakage or rupture of abnormally fragile cutaneous blood vessels....", "[EE40.32] Purpura or bruising due to vascular fragility\n Def: Purpura due to leakage or rupture of abnormally fragile cutaneous blood vessels....\n --PARENT--> [EE40.3] Skin fragility\n Def: Fragility of the skin due principally to genetic or acquired abnormalities of dermal matrix proteins....\n --EXCLUDES--> [?] Epidermal fragility\n Def: Epidermal fragility of unknown or unspecified cause resulting in reduced resistance to mechanical stress and manifesting as abnormal fissuring, erosion or blistering of the skin surface....", "[EE40.0] Corticosteroid-induced skin atrophy\n --PARENT--> [EE40] Atrophy or degeneration of dermal or subcutaneous connective tissue\n Def: A heterogeneous group of disorders resulting from atrophic and degenerative changes in dermal and subcutaneous collagen and elastin....\n --CHILD--> [EE40.1] Stretch marks\n Def: Linear scars attributable to rupture of the normal dermal matrix from distension by abnormal physical forces (pregnancy, obesity, pubertal growth spurt), increased collagenase activity (corticosteroid...", "[EE40.0] Corticosteroid-induced skin atrophy\n --PARENT--> [EE40] Atrophy or degeneration of dermal or subcutaneous connective tissue\n Def: A heterogeneous group of disorders resulting from atrophic and degenerative changes in dermal and subcutaneous collagen and elastin....\n --PARENT--> [?] Disorders of cutaneous connective tissue\n Def: Skin disorders attributable to abnormalities affecting dermal and subcutaneous collagen, elastin and other connective tissue components....", "[9C61.2A] Glaucoma due to drugs\n --PARENT--> [9C61.2] Secondary open-angle glaucoma\n --CHILD--> [9C61.22] Lens-induced secondary open-angle glaucoma", "[9C61.2A] Glaucoma due to drugs\n --PARENT--> [9C61.2] Secondary open-angle glaucoma\n --RELATED_TO--> [?] Glaucoma due to ocular surgery or laser" ]	EE40.32	Purpura or bruising due to vascular fragility	[ { "from_icd11": "NE60", "icd10_code": "T50A95A", "icd10_title": "Adverse effect of other bacterial vaccines, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50Z15A", "icd10_title": "Adverse effect of immunoglobulin, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50Z95A", "icd10_title": "Adverse effect of other vaccines and biological substances, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50A95S", "icd10_title": "Adverse effect of other bacterial vaccines, sequela" }, { "from_icd11": "NE60", "icd10_code": "T50B95A", "icd10_title": "Adverse effect of other viral vaccines, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50A25A", "icd10_title": "Adverse effect of mixed bacterial vaccines without a pertussis component, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50A91A", "icd10_title": "Poisoning by other bacterial vaccines, accidental (unintentional), initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T498X5A", "icd10_title": "Adverse effect of other topical agents, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T48905A", "icd10_title": "Adverse effect of unspecified agents primarily acting on the respiratory system, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T48995A", "icd10_title": "Adverse effect of other agents primarily acting on the respiratory system, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50A15A", "icd10_title": "Adverse effect of pertussis vaccine, including combinations with a pertussis component, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50B15A", "icd10_title": "Adverse effect of smallpox vaccines, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T416X3A", "icd10_title": "" }, { "from_icd11": "NE60", "icd10_code": "T419X3A", "icd10_title": "" }, { "from_icd11": "NE60", "icd10_code": "T418X2A", "icd10_title": "" } ]	T50A95A	Adverse effect of other bacterial vaccines, initial encounter
The uniqueness of our case is twofold: (i) having the combination of HPS with two HAs on the setting of HIV and (ii) demonstrating complete remission of HPS after cessation of didanosine but without resolution of portal hypertension. Because of the inability to obtain exception points, our patient would unlikely receive a liver transplant, except from a living donor. A very extensive workup was initiated to identify the cause of portal hypertension, including a biopsy of the liver parenchyma which was diagnostic of HPS. Furthermore, we measured the hepatic vein wedge pressure which was within normal limits reassuring our presumptive diagnosis of HPS. Based on the current literature, we proceeded with resection of these lesions based on several risk factors for complications, including gender, size (>5 cm), and inflammatory subtype of adenoma. On the final pathology report, well-differentiated HCC was diagnosed along with resolution of the HPS. Even though we understand that tumor biology dictates final outcomes, without timely intervention and appropriate follow-up, there was a high chance that these tumors would have progressed to a point of being nonresectable. This case highlights the broad differential diagnosis that should always be included in the study of any liver disease in this patient population, including the performance of invasive and aggressive tests to arrive at the final diagnosis.	4.117188	0.965332	sec[2]/p[3]	en	0.999996	27812395	https://doi.org/10.1155/2016/1732069	[ "liver", "including", "that", "without", "resolution", "portal", "hypertension", "which", "based", "these" ]	[ { "code": "DB9Z", "title": "Diseases of liver, unspecified" }, { "code": "DB97.Z", "title": "Inflammatory liver disease, unspecified" }, { "code": "DB99.7", "title": "Hepatic failure without mention whether acute or chronic" }, { "code": "LB20.0Y", "title": "Other specified structural developmental anomalies of liver" }, { "code": "LB20.0Z", "title": "Structural developmental anomalies of liver, unspecified" }, { "code": "7A24", "title": "Hypersomnia due to a medication or substance" }, { "code": "9D90", "title": "Vision impairment including blindness" }, { "code": "NE61", "title": "Harmful effects of or exposure to noxious substances, chiefly nonmedicinal as to source, not elsewhere classified" }, { "code": "3A50.02", "title": "Haemoglobin H disease (– α/– – included)" }, { "code": "LA8B.Z", "title": "Congenital anomaly of great arteries including arterial duct, unspecified" } ]	=== ICD-11 CODES FOUND === [DB9Z] Diseases of liver, unspecified Also known as: Diseases of liver, unspecified \| liver disease \| liver condition NOS \| organ liver disease \| hepatopathy [DB97.Z] Inflammatory liver disease, unspecified Also known as: Inflammatory liver disease, unspecified \| Certain specified inflammatory liver diseases \| Nonspecific reactive hepatitis \| inflammatory liver disease \| hepatitis NOS [DB99.7] Hepatic failure without mention whether acute or chronic Also known as: Hepatic failure without mention whether acute or chronic \| liver decompensation \| liver function failure \| hepatic failure NOS \| liver failure NOS [LB20.0Y] Other specified structural developmental anomalies of liver Also known as: Other specified structural developmental anomalies of liver \| Alagille syndrome \| Alagille-Watson syndrome \| Arteriohepatic dysplasia \| Syndromic bile duct paucity [LB20.0Z] Structural developmental anomalies of liver, unspecified Also known as: Structural developmental anomalies of liver, unspecified \| Structural developmental anomalies of liver \| Malformations of liver \| congenital anomaly of liver \| congenital malformation of liver [7A24] Hypersomnia due to a medication or substance Definition: Hypersomnia due to a medication or substance is characterised by excessive nocturnal sleep, daytime sleepiness, or excessive napping that is attributable to the sedating effects of medications, alcohol, or other psychoactive substances, including withdrawal syndromes (e.g., from stimulants) and is sufficiently severe to constitute an independent focus of clinical attention. Note: A definitive diagnosis requires use of polysomnography and multiple sleep latency test (MSLT) to rule out other hype Also known as: Hypersomnia due to a medication or substance \| Hypersomnia due to substances including medications \| Hypersomnolence due to substances including medications Includes: Hypersomnia due to substances including medications [9D90] Vision impairment including blindness Definition: !markdown The table below gives a classification of severity of vision impairment based on visual acuity. For epidemiological studies, it is recommended to collect the following information on visual acuity for each eye, for both eyes open and for distance and near. a) Uncorrected visual acuity b) Presenting visual acuity c) Best corrected visual acuity Blindness is also categorized according to the degree of constriction of the central visual field in the better eye to less than 10 Also known as: Vision impairment including blindness [NE61] Harmful effects of or exposure to noxious substances, chiefly nonmedicinal as to source, not elsewhere classified Also known as: Harmful effects of or exposure to noxious substances, chiefly nonmedicinal as to source, not elsewhere classified \| Harmful effects of or exposure to noxious substances chiefly nonmedicinal as to source, alcohols \| alcohol poisoning \| alcohol toxicity \| Harmful effects of or exposure to noxious substances chiefly nonmedicinal as to source, Ethanol Excludes: corrosions \| Bacterial foodborne intoxications [3A50.02] Haemoglobin H disease (– α/– – included) Definition: Haemoglobin H (HbH) disease is a moderate to severe form of alpha-thalassemia characterised by pronounced microcytic hypochromic haemolytic anaemia. Also known as: Haemoglobin H disease (– α/– – included) \| alpha - /- - or mutational forms of alpha-thalassaemia \| Alpha thalassaemia intermedia [LA8B.Z] Congenital anomaly of great arteries including arterial duct, unspecified Also known as: Congenital anomaly of great arteries including arterial duct, unspecified \| Congenital anomaly of great arteries including arterial duct === GRAPH WALKS === --- Walk 1 --- [DB9Z] Diseases of liver, unspecified --PARENT--> [?] Diseases of liver --RELATED_TO--> [?] Metabolic or transporter liver disease --- Walk 2 --- [DB9Z] Diseases of liver, unspecified --PARENT--> [?] Diseases of liver --CHILD--> [DB91] Acute or subacute hepatic failure Def: Acute and subacute liver failure is characterised by onset of coagulopathy and/or hepatic encephalopathy within 8 weeks of onset of symptoms in a patient without previously known liver diseases.... --- Walk 3 --- [DB97.Z] Inflammatory liver disease, unspecified --PARENT--> [DB97] Certain specified inflammatory liver diseases --CHILD--> [DB97.1] Hepatic berylliosis --- Walk 4 --- [DB97.Z] Inflammatory liver disease, unspecified --PARENT--> [DB97] Certain specified inflammatory liver diseases --RELATED_TO--> [?] Hepatic sarcoidosis Def: This is a syndrome involving abnormal collections of chronic inflammatory cells (granulomas) that can form as nodules in multiple organs, of the liver.... --- Walk 5 --- [DB99.7] Hepatic failure without mention whether acute or chronic --PARENT--> [DB99] Certain specified diseases of liver Def: This is a group of conditions characterised as being in or associated with the liver that are not classified elsewhere.... --RELATED_TO--> [?] Cirrhotic cardiomyopathy Def: Cirrhotic cardiomyopathy is defined as chronic cardiac dysfunction in patients with cirrhosis characterised by blunted contractile responsiveness to stress/exercise and-or altered diastolic relaxation... --- Walk 6 --- [DB99.7] Hepatic failure without mention whether acute or chronic --PARENT--> [DB99] Certain specified diseases of liver Def: This is a group of conditions characterised as being in or associated with the liver that are not classified elsewhere.... --CHILD--> [DB99.2] Hepatorenal syndrome	[ "[DB9Z] Diseases of liver, unspecified\n --PARENT--> [?] Diseases of liver\n --RELATED_TO--> [?] Metabolic or transporter liver disease", "[DB9Z] Diseases of liver, unspecified\n --PARENT--> [?] Diseases of liver\n --CHILD--> [DB91] Acute or subacute hepatic failure\n Def: Acute and subacute liver failure is characterised by onset of coagulopathy and/or hepatic encephalopathy within 8 weeks of onset of symptoms in a patient without previously known liver diseases....", "[DB97.Z] Inflammatory liver disease, unspecified\n --PARENT--> [DB97] Certain specified inflammatory liver diseases\n --CHILD--> [DB97.1] Hepatic berylliosis", "[DB97.Z] Inflammatory liver disease, unspecified\n --PARENT--> [DB97] Certain specified inflammatory liver diseases\n --RELATED_TO--> [?] Hepatic sarcoidosis\n Def: This is a syndrome involving abnormal collections of chronic inflammatory cells (granulomas) that can form as nodules in multiple organs, of the liver....", "[DB99.7] Hepatic failure without mention whether acute or chronic\n --PARENT--> [DB99] Certain specified diseases of liver\n Def: This is a group of conditions characterised as being in or associated with the liver that are not classified elsewhere....\n --RELATED_TO--> [?] Cirrhotic cardiomyopathy\n Def: Cirrhotic cardiomyopathy is defined as chronic cardiac dysfunction in patients with cirrhosis characterised by blunted contractile responsiveness to stress/exercise and-or altered diastolic relaxation...", "[DB99.7] Hepatic failure without mention whether acute or chronic\n --PARENT--> [DB99] Certain specified diseases of liver\n Def: This is a group of conditions characterised as being in or associated with the liver that are not classified elsewhere....\n --CHILD--> [DB99.2] Hepatorenal syndrome" ]	DB9Z	Diseases of liver, unspecified	[ { "from_icd11": "DB9Z", "icd10_code": "K7681", "icd10_title": "Hepatopulmonary syndrome" }, { "from_icd11": "DB9Z", "icd10_code": "K7689", "icd10_title": "Other specified diseases of liver" }, { "from_icd11": "DB9Z", "icd10_code": "K769", "icd10_title": "Liver disease, unspecified" }, { "from_icd11": "DB9Z", "icd10_code": "K77", "icd10_title": "Liver disorders in diseases classified elsewhere" }, { "from_icd11": "DB9Z", "icd10_code": "K762", "icd10_title": "Central hemorrhagic necrosis of liver" }, { "from_icd11": "DB9Z", "icd10_code": "K70-K77", "icd10_title": "" }, { "from_icd11": "DB9Z", "icd10_code": "K778", "icd10_title": "" }, { "from_icd11": "DB9Z", "icd10_code": "K72", "icd10_title": "Hepatic failure, not elsewhere classified" }, { "from_icd11": "DB9Z", "icd10_code": "K76", "icd10_title": "Other diseases of liver" }, { "from_icd11": "DB9Z", "icd10_code": "K768", "icd10_title": "Other specified diseases of liver" }, { "from_icd11": "DB97.Z", "icd10_code": "K7581", "icd10_title": "Nonalcoholic steatohepatitis (NASH)" }, { "from_icd11": "DB97.Z", "icd10_code": "K7589", "icd10_title": "Other specified inflammatory liver diseases" }, { "from_icd11": "DB97.Z", "icd10_code": "K759", "icd10_title": "Inflammatory liver disease, unspecified" }, { "from_icd11": "DB97.Z", "icd10_code": "K752", "icd10_title": "Nonspecific reactive hepatitis" }, { "from_icd11": "DB97.Z", "icd10_code": "K75", "icd10_title": "Other inflammatory liver diseases" } ]	K7681	Hepatopulmonary syndrome
A combined neurosurgery and otolaryngology approach with neuronavigation was utilized. A lumbar drain was placed for CSF diversion. Using a rigid 0-degree endoscope for visualization, a nasoseptal flap was harvested. Bilateral posterior ethmoidectomies and septostomy were performed, followed by a wide opening of the sphenoid sinus from the clivus to planum sphenoidale. The bony septum was flattened with a high-speed drill and the medial opticocarotid recesses were identified bilaterally. A craniectomy was performed encompassing the floor of the sella and the anterior portion of the planum sphenoidale, just posterior to the cribriform plate. The sella and planum dura were opened, as was the medial opticocarotid recesses bilaterally to gain lateral access to the suprasellar tumor. Horizontal incisions were made in the dura above and below the superior intracavernous sinus. The dura was reflected in a cruciate fashion and the pituitary gland was noted adjacent to the optic chiasm due to its superior displacement by the tumor. The optic chiasm was then identified superiorly; the tumor and its capsule were resected sequentially and sharply dissected off the optic chiasm, using rigid 0-degree and 30-degree endoscopes for visualization. The closure/skullbase reconstruction was performed using non-suturable dural allograft inlay, a nasoseptal flap, and a dural sealant (DuraSeal® Covidien, Dublin, Ireland).	4.058594	0.809082	sec[1]/sec[0]/p[0]	en	0.999999	27014537	https://doi.org/10.7759/cureus.503	[ "using", "degree", "planum", "dura", "tumor", "optic", "chiasm", "rigid", "visualization", "nasoseptal" ]	[ { "code": "QE11.Z", "title": "Hazardous drug use, unspecified" }, { "code": "6C4Z", "title": "Disorders due to substance use, unspecified" }, { "code": "QE11.3", "title": "Hazardous use of cocaine" }, { "code": "QE11.2", "title": "Hazardous use of sedatives, hypnotics or anxiolytics" }, { "code": "QE11.1", "title": "Hazardous use of cannabis" }, { "code": "BC63.2Z", "title": "Complete atrioventricular block, unspecified" }, { "code": "9D46", "title": "Impairment of binocular functions" }, { "code": "JB09.0", "title": "First degree perineal laceration during delivery" }, { "code": "JB09.2", "title": "Third degree perineal laceration during delivery" }, { "code": "JB09.1", "title": "Second degree perineal laceration during delivery" } ]	=== ICD-11 CODES FOUND === [QE11.Z] Hazardous drug use, unspecified Also known as: Hazardous drug use, unspecified \| Hazardous drug use \| chronic drug use NOS \| chronic IV substance use \| drug use nos [6C4Z] Disorders due to substance use, unspecified Also known as: Disorders due to substance use, unspecified \| Disorders due to substance abuse \| drug use disorder \| Bad trips due to drugs [QE11.3] Hazardous use of cocaine Definition: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health professionals. The increased risk may be from the frequency of cocaine use, from the amount used on a given occasion, from risky behaviours associated with cocaine use or the context of use, from a harmful route of administration, or from a combination of these. The risk may be related to short-term eff Also known as: Hazardous use of cocaine \| cocaine use \| intravenous cocaine use \| Hazardous use of crack cocaine \| crack cocaine use Excludes: Disorders due to use of cocaine [QE11.2] Hazardous use of sedatives, hypnotics or anxiolytics Definition: A pattern of use of sedatives, hypnotics or anxiolytics that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health professionals. The increased risk may be from the frequency of use of sedatives, hypnotics or anxiolytics, from the amount used on a given occasion, from risky behaviours associated with use of sedatives, hypnotics or anxiolytics or the context of use, from a harmful route Also known as: Hazardous use of sedatives, hypnotics or anxiolytics \| Hazardous use of anxiolytics \| Hazardous use of hypnotics \| hypnotic use \| Hazardous use of sedatives Excludes: Disorders due to use of sedatives, hypnotics or anxiolytics [QE11.1] Hazardous use of cannabis Definition: A pattern of cannabis use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health professionals. The increased risk may be from the frequency of cannabis use, from the amount used on a given occasion, from risky behaviours associated with cannabis use or the context of use, from a harmful route of administration, or from a combination of these. The risk may be related to short-term Also known as: Hazardous use of cannabis \| marijuana use \| cannabis use Excludes: Disorders due to use of cannabis [BC63.2Z] Complete atrioventricular block, unspecified Also known as: Complete atrioventricular block, unspecified \| Complete atrioventricular block \| Third-degree block \| complete atrioventricular heart block \| complete heart block [9D46] Impairment of binocular functions Also known as: Impairment of binocular functions \| Tobacco amblyopia \| Amblyopia, type not specified \| amblyopic \| Amblyopia ex anopsia [JB09.0] First degree perineal laceration during delivery Definition: Perineal lacerations involving the fourchette, perineal skin, and vaginal mucous membrane but not the underlying fascia and muscle. Also known as: First degree perineal laceration during delivery \| first degree perineal laceration \| laceration of superficial layers of perineal structures \| obstetrical laceration, first degree \| perineal obstetric rupture, first degree [JB09.2] Third degree perineal laceration during delivery Definition: Perineal lacerations extending farther to involve the anal sphincter. Also known as: Third degree perineal laceration during delivery \| obstetrical laceration, third degree \| third degree perineal laceration \| third degree obstetric perineal rupture \| third degree perineal laceration, with delivery Excludes: that involving anal or rectal mucosa [JB09.1] Second degree perineal laceration during delivery Definition: Perineal lacerations involve, in addition, the fascia and muscles of the perineal body but not the anal sphincter. Also known as: Second degree perineal laceration during delivery \| obstetrical laceration, second degree \| second degree tear \| Injury of pelvic floor complicating delivery \| First degree perineal laceration, rupture or tear also involving the pelvic floor Excludes: that involving anal sphincter === GRAPH WALKS === --- Walk 1 --- [QE11.Z] Hazardous drug use, unspecified --PARENT--> [QE11] Hazardous drug use Def: A pattern of use of psychoactive substance(s) other than nicotine or alcohol that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent... --CHILD--> [QE11.1] Hazardous use of cannabis Def: A pattern of cannabis use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health pro... --- Walk 2 --- [QE11.Z] Hazardous drug use, unspecified --PARENT--> [QE11] Hazardous drug use Def: A pattern of use of psychoactive substance(s) other than nicotine or alcohol that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent... --PARENT--> [?] Hazardous substance use Def: Hazardous substance use is a pattern of psychoactive substance use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warr... --- Walk 3 --- [6C4Z] Disorders due to substance use, unspecified --PARENT--> [?] Disorders due to substance use Def: Disorders due to substance use include disorders that result from a single occasion or repeated use of substances that have psychoactive properties, including certain medications. Disorders related to... --CHILD--> [6C41] Disorders due to use of cannabis Def: Disorders due to use of cannabis are characterised by the pattern and consequences of cannabis use. Cannabis is the collective term for a range of psychoactive preparations of the cannabis plant, Cann... --- Walk 4 --- [6C4Z] Disorders due to substance use, unspecified --PARENT--> [?] Disorders due to substance use Def: Disorders due to substance use include disorders that result from a single occasion or repeated use of substances that have psychoactive properties, including certain medications. Disorders related to... --CHILD--> [6C41] Disorders due to use of cannabis Def: Disorders due to use of cannabis are characterised by the pattern and consequences of cannabis use. Cannabis is the collective term for a range of psychoactive preparations of the cannabis plant, Cann... --- Walk 5 --- [QE11.3] Hazardous use of cocaine Def: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health prof... --EXCLUDES--> [?] Disorders due to use of cocaine Def: Disorders due to use of cocaine are characterised by the pattern and consequences of cocaine use. Cocaine is a compound found in the leaves of the coca plant, Erythroxylum coca, which is indigenous to... --EXCLUDES--> [?] Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone Def: Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone are characterised by the pattern and consequences of use of these substances. There is a wide array of natur... --- Walk 6 --- [QE11.3] Hazardous use of cocaine Def: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health prof... --EXCLUDES--> [?] Disorders due to use of cocaine Def: Disorders due to use of cocaine are characterised by the pattern and consequences of cocaine use. Cocaine is a compound found in the leaves of the coca plant, Erythroxylum coca, which is indigenous to... --CHILD--> [?] Episode of harmful use of cocaine Def: An episode of use of cocaine that has caused damage to a person’s physical or mental health or has resulted in behaviour leading to harm to the health of others. Harm to health of the individual occur...	[ "[QE11.Z] Hazardous drug use, unspecified\n --PARENT--> [QE11] Hazardous drug use\n Def: A pattern of use of psychoactive substance(s) other than nicotine or alcohol that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent...\n --CHILD--> [QE11.1] Hazardous use of cannabis\n Def: A pattern of cannabis use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health pro...", "[QE11.Z] Hazardous drug use, unspecified\n --PARENT--> [QE11] Hazardous drug use\n Def: A pattern of use of psychoactive substance(s) other than nicotine or alcohol that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent...\n --PARENT--> [?] Hazardous substance use\n Def: Hazardous substance use is a pattern of psychoactive substance use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warr...", "[6C4Z] Disorders due to substance use, unspecified\n --PARENT--> [?] Disorders due to substance use\n Def: Disorders due to substance use include disorders that result from a single occasion or repeated use of substances that have psychoactive properties, including certain medications. Disorders related to...\n --CHILD--> [6C41] Disorders due to use of cannabis\n Def: Disorders due to use of cannabis are characterised by the pattern and consequences of cannabis use. Cannabis is the collective term for a range of psychoactive preparations of the cannabis plant, Cann...", "[6C4Z] Disorders due to substance use, unspecified\n --PARENT--> [?] Disorders due to substance use\n Def: Disorders due to substance use include disorders that result from a single occasion or repeated use of substances that have psychoactive properties, including certain medications. Disorders related to...\n --CHILD--> [6C41] Disorders due to use of cannabis\n Def: Disorders due to use of cannabis are characterised by the pattern and consequences of cannabis use. Cannabis is the collective term for a range of psychoactive preparations of the cannabis plant, Cann...", "[QE11.3] Hazardous use of cocaine\n Def: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health prof...\n --EXCLUDES--> [?] Disorders due to use of cocaine\n Def: Disorders due to use of cocaine are characterised by the pattern and consequences of cocaine use. Cocaine is a compound found in the leaves of the coca plant, Erythroxylum coca, which is indigenous to...\n --EXCLUDES--> [?] Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone\n Def: Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone are characterised by the pattern and consequences of use of these substances. There is a wide array of natur...", "[QE11.3] Hazardous use of cocaine\n Def: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health prof...\n --EXCLUDES--> [?] Disorders due to use of cocaine\n Def: Disorders due to use of cocaine are characterised by the pattern and consequences of cocaine use. Cocaine is a compound found in the leaves of the coca plant, Erythroxylum coca, which is indigenous to...\n --CHILD--> [?] Episode of harmful use of cocaine\n Def: An episode of use of cocaine that has caused damage to a person’s physical or mental health or has resulted in behaviour leading to harm to the health of others. Harm to health of the individual occur..." ]	QE11.Z	Hazardous drug use, unspecified	[ { "from_icd11": "QE11.Z", "icd10_code": "Z722", "icd10_title": "" }, { "from_icd11": "6C4Z", "icd10_code": "F1910", "icd10_title": "Other psychoactive substance abuse, uncomplicated" }, { "from_icd11": "6C4Z", "icd10_code": "F1911", "icd10_title": "Other psychoactive substance abuse, in remission" }, { "from_icd11": "6C4Z", "icd10_code": "F19129", "icd10_title": "Other psychoactive substance abuse with intoxication, unspecified" }, { "from_icd11": "6C4Z", "icd10_code": "F19121", "icd10_title": "Other psychoactive substance abuse with intoxication delirium" }, { "from_icd11": "6C4Z", "icd10_code": "F1920", "icd10_title": "Other psychoactive substance dependence, uncomplicated" }, { "from_icd11": "6C4Z", "icd10_code": "F19239", "icd10_title": "Other psychoactive substance dependence with withdrawal, unspecified" }, { "from_icd11": "6C4Z", "icd10_code": "F1914", "icd10_title": "Other psychoactive substance abuse with psychoactive substance-induced mood disorder" }, { "from_icd11": "6C4Z", "icd10_code": "F1921", "icd10_title": "Other psychoactive substance dependence, in remission" }, { "from_icd11": "6C4Z", "icd10_code": "F19221", "icd10_title": "Other psychoactive substance dependence with intoxication delirium" }, { "from_icd11": "6C4Z", "icd10_code": "F19180", "icd10_title": "Other psychoactive substance abuse with psychoactive substance-induced anxiety disorder" }, { "from_icd11": "6C4Z", "icd10_code": "F1924", "icd10_title": "Other psychoactive substance dependence with psychoactive substance-induced mood disorder" }, { "from_icd11": "6C4Z", "icd10_code": "F1917", "icd10_title": "Other psychoactive substance abuse with psychoactive substance-induced persisting dementia" }, { "from_icd11": "6C4Z", "icd10_code": "F19229", "icd10_title": "Other psychoactive substance dependence with intoxication, unspecified" }, { "from_icd11": "6C4Z", "icd10_code": "F1919", "icd10_title": "Other psychoactive substance abuse with unspecified psychoactive substance-induced disorder" } ]	Z722
Gastrointestinal stromal tumors (GISTs) are rare tumors with an estimated incidence of 1.5/100,000/year but are the most common mesenchymal tumors of the gastrointestinal tract . They are most commonly found in the stomach (60 %) and small intestine (35 %), and <5 % arise in the rectum . Although complete surgical excision with histologically negative margins is the primary treatment of choice for localized GISTs, resection of rectal GISTs can be difficult in the narrow pelvic space, and a large rectal GIST has a risk of rupture during surgery and often requires abdominoperineal resection. GISTs express KIT proto-oncogenic receptor tyrosine kinase and commonly harbor activating mutations in the KIT gene . Imatinib is an inhibitor of tyrosine kinases including KIT, and targets the aberrant signaling pathways that are critical for tumor cell proliferation and survival, thus showing anti-tumor activity . The effectiveness of imatinib in the treatment of GISTs was first described in 2001 , and the remarkable response to imatinib in unresectable or metastatic GISTs has led to the neoadjuvant treatment strategy for locally advanced GISTs . Despite the excellent view of laparoscopy, there are only a few that reported cases of its use in surgery for rectal GIST . We report here a patient with a large rectal GIST who safely underwent laparoscopic anus-preserving surgery after neoadjuvant imatinib treatment.	4.320313	0.868164	sec[0]/p[0]	en	0.999997	26957123	https://doi.org/10.1186/s12957-016-0837-1	[ "gists", "rectal", "imatinib", "tumors", "gist", "gastrointestinal", "commonly", "resection", "large", "tyrosine" ]	[ { "code": "2B5B.Z", "title": "Gastrointestinal stromal tumour of unspecified gastrointestinal sites" }, { "code": "2E87", "title": "Benign gastrointestinal stromal tumour" }, { "code": "2B5B.0", "title": "Gastrointestinal stromal tumour of stomach" }, { "code": "2B5B.1", "title": "Gastrointestinal stromal tumour of small intestine" }, { "code": "2B5B.Y", "title": "Gastrointestinal stromal tumour of other gastrointestinal sites" }, { "code": "DB30.4", "title": "Stenosis of the rectum" }, { "code": "DB31.0&XA4KU2", "title": "Rectal fistula" }, { "code": "NB91.91", "title": "Laceration of rectum" }, { "code": "2F90.1", "title": "Neoplasms of unknown behaviour of rectum" }, { "code": "DB32.2Z&XA4KU2", "title": "Rectal dilatation" } ]	=== ICD-11 CODES FOUND === [2B5B.Z] Gastrointestinal stromal tumour of unspecified gastrointestinal sites Also known as: Gastrointestinal stromal tumour of unspecified gastrointestinal sites \| Gastrointestinal stromal tumour, primary site \| GIST - [gastrointestinal stromal tumour] [2E87] Benign gastrointestinal stromal tumour Also known as: Benign gastrointestinal stromal tumour \| Benign gastrointestinal stromal tumour of stomach \| Benign GIST - [gastrointestinal stromal tumour] of stomach \| Benign gastrointestinal stromal tumour of duodenum \| Benign GIST - [gastrointestinal stromal tumour] of duodenum [2B5B.0] Gastrointestinal stromal tumour of stomach Definition: A gastrointestinal stromal tumour that arises from the stomach. It covers a spectrum of benign to malignant mesenchymal neoplasms and includes most gastric smooth muscle tumours, leiomyoblastomas, and tumours formerly called gastrointestinal autonomic nerve tumours. Also known as: Gastrointestinal stromal tumour of stomach \| Malignant GIST - [gastrointestinal stromal tumour] of stomach \| Gastrointestinal stromal tumour of cardia of stomach \| Gastrointestinal stromal tumour of body of stomach \| Gastrointestinal stromal tumour of pyloric antrum of stomach [2B5B.1] Gastrointestinal stromal tumour of small intestine Definition: A gastrointestinal stromal tumour that arises from the small intestine. It usually affects adults over fifty years of age. The majority of cases have spindle cell morphology. The prognosis depends on the tumour size and the mitotic activity. Also known as: Gastrointestinal stromal tumour of small intestine \| Malignant GIST - [gastrointestinal stromal tumour] of small intestine \| Gastrointestinal stromal tumour of jejunum \| Gastrointestinal stromal tumour of ileum \| Gastrointestinal stromal tumour of Meckel diverticulum [2B5B.Y] Gastrointestinal stromal tumour of other gastrointestinal sites Also known as: Gastrointestinal stromal tumour of other gastrointestinal sites \| Gastrointestinal stromal tumour of other gastrointestinal sites \| Gastrointestinal stromal tumour of oesophagus \| Gastrointestinal stromal tumour of rectum \| Gastrointestinal stromal tumour of colon [DB30.4] Stenosis of the rectum Definition: Rectal stenosis is defined as narrowing of the rectum. Also known as: Stenosis of the rectum \| obstructed rectum \| rectal stenosis \| stricture of rectum \| rectal obstruction [NB91.91] Laceration of rectum Also known as: Laceration of rectum [2F90.1] Neoplasms of unknown behaviour of rectum Also known as: Neoplasms of unknown behaviour of rectum \| rectum tumour NOS === GRAPH WALKS === --- Walk 1 --- [2B5B.Z] Gastrointestinal stromal tumour of unspecified gastrointestinal sites --PARENT--> [2B5B] Gastrointestinal stromal tumour, primary site Def: This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiat... --CHILD--> [2B5B.1] Gastrointestinal stromal tumour of small intestine Def: A gastrointestinal stromal tumour that arises from the small intestine. It usually affects adults over fifty years of age. The majority of cases have spindle cell morphology. The prognosis depends on ... --- Walk 2 --- [2B5B.Z] Gastrointestinal stromal tumour of unspecified gastrointestinal sites --PARENT--> [2B5B] Gastrointestinal stromal tumour, primary site Def: This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiat... --CHILD--> [2B5B.Y] Gastrointestinal stromal tumour of other gastrointestinal sites --- Walk 3 --- [2E87] Benign gastrointestinal stromal tumour --PARENT--> [?] Benign mesenchymal neoplasms Def: Bening neoplasms of muscle, fat, fibrous tissue, bone, cartilage, and blood vessels.... --CHILD--> [2E81] Benign vascular neoplasms --- Walk 4 --- [2E87] Benign gastrointestinal stromal tumour --PARENT--> [?] Benign mesenchymal neoplasms Def: Bening neoplasms of muscle, fat, fibrous tissue, bone, cartilage, and blood vessels.... --CHILD--> [2E81] Benign vascular neoplasms --- Walk 5 --- [2B5B.0] Gastrointestinal stromal tumour of stomach Def: A gastrointestinal stromal tumour that arises from the stomach. It covers a spectrum of benign to malignant mesenchymal neoplasms and includes most gastric smooth muscle tumours, leiomyoblastomas, and... --PARENT--> [2B5B] Gastrointestinal stromal tumour, primary site Def: This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiat... --PARENT--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --- Walk 6 --- [2B5B.0] Gastrointestinal stromal tumour of stomach Def: A gastrointestinal stromal tumour that arises from the stomach. It covers a spectrum of benign to malignant mesenchymal neoplasms and includes most gastric smooth muscle tumours, leiomyoblastomas, and... --PARENT--> [2B5B] Gastrointestinal stromal tumour, primary site Def: This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiat... --CHILD--> [2B5B.0] Gastrointestinal stromal tumour of stomach Def: A gastrointestinal stromal tumour that arises from the stomach. It covers a spectrum of benign to malignant mesenchymal neoplasms and includes most gastric smooth muscle tumours, leiomyoblastomas, and...	[ "[2B5B.Z] Gastrointestinal stromal tumour of unspecified gastrointestinal sites\n --PARENT--> [2B5B] Gastrointestinal stromal tumour, primary site\n Def: This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiat...\n --CHILD--> [2B5B.1] Gastrointestinal stromal tumour of small intestine\n Def: A gastrointestinal stromal tumour that arises from the small intestine. It usually affects adults over fifty years of age. The majority of cases have spindle cell morphology. The prognosis depends on ...", "[2B5B.Z] Gastrointestinal stromal tumour of unspecified gastrointestinal sites\n --PARENT--> [2B5B] Gastrointestinal stromal tumour, primary site\n Def: This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiat...\n --CHILD--> [2B5B.Y] Gastrointestinal stromal tumour of other gastrointestinal sites", "[2E87] Benign gastrointestinal stromal tumour\n --PARENT--> [?] Benign mesenchymal neoplasms\n Def: Bening neoplasms of muscle, fat, fibrous tissue, bone, cartilage, and blood vessels....\n --CHILD--> [2E81] Benign vascular neoplasms", "[2E87] Benign gastrointestinal stromal tumour\n --PARENT--> [?] Benign mesenchymal neoplasms\n Def: Bening neoplasms of muscle, fat, fibrous tissue, bone, cartilage, and blood vessels....\n --CHILD--> [2E81] Benign vascular neoplasms", "[2B5B.0] Gastrointestinal stromal tumour of stomach\n Def: A gastrointestinal stromal tumour that arises from the stomach. It covers a spectrum of benign to malignant mesenchymal neoplasms and includes most gastric smooth muscle tumours, leiomyoblastomas, and...\n --PARENT--> [2B5B] Gastrointestinal stromal tumour, primary site\n Def: This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiat...\n --PARENT--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...", "[2B5B.0] Gastrointestinal stromal tumour of stomach\n Def: A gastrointestinal stromal tumour that arises from the stomach. It covers a spectrum of benign to malignant mesenchymal neoplasms and includes most gastric smooth muscle tumours, leiomyoblastomas, and...\n --PARENT--> [2B5B] Gastrointestinal stromal tumour, primary site\n Def: This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiat...\n --CHILD--> [2B5B.0] Gastrointestinal stromal tumour of stomach\n Def: A gastrointestinal stromal tumour that arises from the stomach. It covers a spectrum of benign to malignant mesenchymal neoplasms and includes most gastric smooth muscle tumours, leiomyoblastomas, and..." ]	2B5B.Z	Gastrointestinal stromal tumour of unspecified gastrointestinal sites	[ { "from_icd11": "DB30.4", "icd10_code": "K624", "icd10_title": "Stenosis of anus and rectum" }, { "from_icd11": "2F90.1", "icd10_code": "D375", "icd10_title": "Neoplasm of uncertain behavior of rectum" } ]	K624	Stenosis of anus and rectum
The gross examination during surgery showed inflammation around the bilateral ovaries that was so marked that it prevented identification of individual organs. The bilateral ovaries and uterus were firm to palpate; however, the vagina in the pelvic cavity was relatively soft on palpitation. The inflammatory lesions including the ovaries and the uterus containing a uterine fibroid were resected to control oozing hemorrhage from the pelvic cavity because the patient showed evidence of DIC. During this procedure, the cystic component was partially damaged and discharged a small amount of purulent fluid, which subsequent cultures showed to contain ESBL-producing E.coli . Resected specimens of the bilateral ovaries showed marked swelling and thick-walled multilocular cystic lesions with intraluminal abscesses . Microscopic examination of the resected specimen revealed infiltration of foamy cells and neutrophils into the abscess cavity . No cell types showed atypical mitotic images or pleomorphisms. Fig. 3 Resected specimen of ovary, showing marked swelling of the bilateral ovaries with intraluminal abscess. Pathological examination revealed the presence of ectopic endometriosis around the ovary ( white arrowheads ) Fig. 4 a HE stain ×10. The ovary showed a high degree of neutrophil infiltration with abscess formation. b HE stain ×100. High-power magnification showed a cluster of neutrophils in the ovary	3.960938	0.897461	sec[1]/p[2]	en	0.999998	26366363	https://doi.org/10.1186/s40792-015-0069-6	[ "ovaries", "resected", "ovary", "cavity", "abscess", "around", "that", "uterus", "pelvic", "lesions" ]	[ { "code": "QF01.10", "title": "Acquired absence of female genital organs" }, { "code": "LB45.1", "title": "46,XX gonadal dysgenesis" }, { "code": "1B12.5", "title": "Tuberculosis of the genitourinary system" }, { "code": "GA32.0", "title": "Ovarian hyperstimulation syndrome" }, { "code": "GA0Z", "title": "Inflammatory disorders of the female genital tract, unspecified" }, { "code": "GA1Z&XA1QK0", "title": "Noninflammatory disorders of ovary" }, { "code": "GA07.Z&XA1QK0", "title": "Inflammation of ovary" }, { "code": "GA30.6", "title": "Premature ovarian failure" }, { "code": "JA01.2", "title": "Ovarian pregnancy" }, { "code": "DA08.0", "title": "Dental caries" } ]	=== ICD-11 CODES FOUND === [QF01.10] Acquired absence of female genital organs Also known as: Acquired absence of female genital organs \| Acquired absence of cervix \| amputation of cervix \| Acquired absence of the uterus \| acquired uterine absence [LB45.1] 46,XX gonadal dysgenesis Definition: Karyotype 46 XX; Gonads: gonadal dysgenesis (streak gonads); Phenotype female with symptoms like primary amenorrhea, hypergonadotropic hypogonadism, normal stature and no other abnormalities. Also known as: 46,XX gonadal dysgenesis \| Follicular stimulating hormone-resistant ovaries \| Resistant ovary syndrome \| 46,XX pure gonadal dysgenesis \| 46,XX complete gonadal dysgenesis [1B12.5] Tuberculosis of the genitourinary system Definition: Tuberculosis involving the urinary tract and/or reproductive organs. The primary site of infection is most commonly the kidney as a result of haematogenous spread from distant sites: infection may then spread further down the urinary tract and/or to the reproductive organs. Genital infection may be sexually transmitted. Also known as: Tuberculosis of the genitourinary system \| urogenital tuberculosis \| Tuberculosis of the urinary system \| urinary tract TB - [tuberculosis] \| Tuberculosis of kidney or ureter [GA32.0] Ovarian hyperstimulation syndrome Definition: A disease of the endocrine system, caused by elevated human chorionic gonadotropin hormone, commonly after the use of injectable fertility treatments. This disease is characterised by ovarian enlargement, and hemodynamic or metabolic complications. This disease may also present with abdominal pain, abdominal bloating, or weight gain depending on graded symptoms. Also known as: Ovarian hyperstimulation syndrome \| OHSS - [Ovarian hyperstimulation syndrome] \| hyperstimulation of ovaries NOS \| Hyperstimulation of ovaries associated with induced ovulation Includes: Hyperstimulation of ovaries associated with induced ovulation [GA0Z] Inflammatory disorders of the female genital tract, unspecified Also known as: Inflammatory disorders of the female genital tract, unspecified \| Inflammatory disorders of the vagina \| Inflammatory disorders of cervix uteri \| Inflammatory disorders of the pelvic cavity including fallopian tubes and ovaries [GA30.6] Premature ovarian failure Definition: Menopause occurring spontaneously before 40 years of age, generally resulting in secondary amenorrhea although some women may exhibit intermittent ovarian function and ovulation, with a minority conceiving and delivering a pregnancy. POF/POI occurs mostly without a known cause, but can be caused by the following conditions: numerical and structural chromosomal abnormalities, Fragile X (FMR1) premutations, autoimmune disorders, radiation therapy, chemotherapy, galactosemia, and other rare enzyme Also known as: Premature ovarian failure \| female hypergonadotropic hypogonadism \| hypergonadotrophic ovarian failure \| primary female hypogonadism \| POF - [premature ovarian failure] Excludes: Isolated gonadotropin deficiency \| Postprocedural ovarian failure [JA01.2] Ovarian pregnancy Definition: A condition characterised by implantation of the embryo within the ovary during pregnancy. Also known as: Ovarian pregnancy [DA08.0] Dental caries Definition: A condition characterised by localised destruction of calcified tissue, initiated on the tooth surface by decalcification of the enamel, followed by the enzymatic lysis of organic structures, resulting in cavity formation. Also known as: Dental caries \| Dental decay \| carious teeth \| dental cavity \| saprodontia Includes: Dental decay === GRAPH WALKS === --- Walk 1 --- [QF01.10] Acquired absence of female genital organs --RELATED_TO--> [?] Traumatic amputation of entire vulva --PARENT--> [?] Traumatic amputation of external genital organs --- Walk 2 --- [QF01.10] Acquired absence of female genital organs --RELATED_TO--> [?] Female Genital Mutilation Def: A condition caused by procedures or other interventions for non-medical purposes. This condition is characterised by the partial or total removal of the external female genitalia or other injury to th... --EXCLUDES--> [?] Traumatic amputation of part of vulva --- Walk 3 --- [LB45.1] 46,XX gonadal dysgenesis Def: Karyotype 46 XX; Gonads: gonadal dysgenesis (streak gonads); Phenotype female with symptoms like primary amenorrhea, hypergonadotropic hypogonadism, normal stature and no other abnormalities.... --PARENT--> [LB45] Structural developmental anomalies of ovaries, fallopian tubes or broad ligaments --CHILD--> [LB45.1] 46,XX gonadal dysgenesis Def: Karyotype 46 XX; Gonads: gonadal dysgenesis (streak gonads); Phenotype female with symptoms like primary amenorrhea, hypergonadotropic hypogonadism, normal stature and no other abnormalities.... --- Walk 4 --- [LB45.1] 46,XX gonadal dysgenesis Def: Karyotype 46 XX; Gonads: gonadal dysgenesis (streak gonads); Phenotype female with symptoms like primary amenorrhea, hypergonadotropic hypogonadism, normal stature and no other abnormalities.... --PARENT--> [LB45] Structural developmental anomalies of ovaries, fallopian tubes or broad ligaments --PARENT--> [?] Structural developmental anomalies of the female genital system --- Walk 5 --- [1B12.5] Tuberculosis of the genitourinary system Def: Tuberculosis involving the urinary tract and/or reproductive organs. The primary site of infection is most commonly the kidney as a result of haematogenous spread from distant sites: infection may the... --PARENT--> [1B12] Tuberculosis of other systems and organs --CHILD--> [1B12.0] Tuberculosis of heart Def: Mycobacterium tuberculosis infection involving the heart and pericardium... --- Walk 6 --- [1B12.5] Tuberculosis of the genitourinary system Def: Tuberculosis involving the urinary tract and/or reproductive organs. The primary site of infection is most commonly the kidney as a result of haematogenous spread from distant sites: infection may the... --PARENT--> [1B12] Tuberculosis of other systems and organs --CHILD--> [1B12.2] Tuberculosis of ear Def: This is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is of the ear....	[ "[QF01.10] Acquired absence of female genital organs\n --RELATED_TO--> [?] Traumatic amputation of entire vulva\n --PARENT--> [?] Traumatic amputation of external genital organs", "[QF01.10] Acquired absence of female genital organs\n --RELATED_TO--> [?] Female Genital Mutilation\n Def: A condition caused by procedures or other interventions for non-medical purposes. This condition is characterised by the partial or total removal of the external female genitalia or other injury to th...\n --EXCLUDES--> [?] Traumatic amputation of part of vulva", "[LB45.1] 46,XX gonadal dysgenesis\n Def: Karyotype 46 XX; Gonads: gonadal dysgenesis (streak gonads); Phenotype female with symptoms like primary amenorrhea, hypergonadotropic hypogonadism, normal stature and no other abnormalities....\n --PARENT--> [LB45] Structural developmental anomalies of ovaries, fallopian tubes or broad ligaments\n --CHILD--> [LB45.1] 46,XX gonadal dysgenesis\n Def: Karyotype 46 XX; Gonads: gonadal dysgenesis (streak gonads); Phenotype female with symptoms like primary amenorrhea, hypergonadotropic hypogonadism, normal stature and no other abnormalities....", "[LB45.1] 46,XX gonadal dysgenesis\n Def: Karyotype 46 XX; Gonads: gonadal dysgenesis (streak gonads); Phenotype female with symptoms like primary amenorrhea, hypergonadotropic hypogonadism, normal stature and no other abnormalities....\n --PARENT--> [LB45] Structural developmental anomalies of ovaries, fallopian tubes or broad ligaments\n --PARENT--> [?] Structural developmental anomalies of the female genital system", "[1B12.5] Tuberculosis of the genitourinary system\n Def: Tuberculosis involving the urinary tract and/or reproductive organs. The primary site of infection is most commonly the kidney as a result of haematogenous spread from distant sites: infection may the...\n --PARENT--> [1B12] Tuberculosis of other systems and organs\n --CHILD--> [1B12.0] Tuberculosis of heart\n Def: Mycobacterium tuberculosis infection involving the heart and pericardium...", "[1B12.5] Tuberculosis of the genitourinary system\n Def: Tuberculosis involving the urinary tract and/or reproductive organs. The primary site of infection is most commonly the kidney as a result of haematogenous spread from distant sites: infection may the...\n --PARENT--> [1B12] Tuberculosis of other systems and organs\n --CHILD--> [1B12.2] Tuberculosis of ear\n Def: This is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. This diagnosis is of the ear...." ]	QF01.10	Acquired absence of female genital organs	[ { "from_icd11": "LB45.1", "icd10_code": "Q99", "icd10_title": "Other chromosome abnormalities, not elsewhere classified" }, { "from_icd11": "LB45.1", "icd10_code": "Q991", "icd10_title": "46, XX true hermaphrodite" }, { "from_icd11": "1B12.5", "icd10_code": "A1817", "icd10_title": "Tuberculous female pelvic inflammatory disease" }, { "from_icd11": "1B12.5", "icd10_code": "A1810", "icd10_title": "Tuberculosis of genitourinary system, unspecified" }, { "from_icd11": "1B12.5", "icd10_code": "A1811", "icd10_title": "Tuberculosis of kidney and ureter" }, { "from_icd11": "1B12.5", "icd10_code": "A181", "icd10_title": "Tuberculosis of genitourinary system" }, { "from_icd11": "1B12.5", "icd10_code": "N330", "icd10_title": "" }, { "from_icd11": "1B12.5", "icd10_code": "N741", "icd10_title": "" }, { "from_icd11": "GA32.0", "icd10_code": "N981", "icd10_title": "Hyperstimulation of ovaries" }, { "from_icd11": "GA0Z", "icd10_code": "N7689", "icd10_title": "Other specified inflammation of vagina and vulva" }, { "from_icd11": "GA0Z", "icd10_code": "N7681", "icd10_title": "Mucositis (ulcerative) of vagina and vulva" }, { "from_icd11": "GA0Z", "icd10_code": "N72", "icd10_title": "Inflammatory disease of cervix uteri" }, { "from_icd11": "GA0Z", "icd10_code": "N70-N77", "icd10_title": "" }, { "from_icd11": "GA0Z", "icd10_code": "N76", "icd10_title": "Other inflammation of vagina and vulva" }, { "from_icd11": "GA0Z", "icd10_code": "N768", "icd10_title": "Other specified inflammation of vagina and vulva" } ]	Q99	Other chromosome abnormalities, not elsewhere classified
In 2012, an 18-year-old woman with no major medical history sought care at an outpatient infectious diseases clinic in Tbilisi with a 2-week history of weakness, malaise, fever > 38°C for the previous 10 days, enlarging right neck mass, and occasional night sweats. She lived in a residential building in an urban area within Tbilisi. She denied recent travel outside the city, contacts with sick persons, exposure to farm animals, or having pets at home. Physical examination indicated right cervical lymphadenopathy with multiple enlarged, soft, tender lymph nodes, 1 of which was fluctuant on palpation. Ultrasound showed 4 enlarged lymph nodes: 2 in the anterior cervical region (14 mm and 17 mm) and 2 in the posterior cervical region (29 and 38 mm). The largest lymph node had central attenuation with a hypoechoic area suggestive of pus. Laboratory test results were as follows: leukocyte count 9.2 cells/μL (reference 4.0–11.0 cells/μL) with 6.7% (reference 2.5%–7.5%) neutrophils; platelets 358,000/μL (reference 150,000–450,000/μL); hemoglobin 15.4 g/dL (reference 14.0–17.5 g/dL); C-reactive protein 16 mg/L (reference 0–10 mg/L); and erythrocyte sedimentation rate 56 mm/h (reference <30 mm/h). Chest radiograph showed no abnormalities. Serum was negative for antibodies against cytomegalovirus, Epstein-Barr virus, Toxoplasma , and HIV. Tuberculin skin test result of 4-mm induration was considered negative.	3.960938	0.977051	sec[0]/p[0]	en	0.999996	26889959	https://doi.org/10.3201/eid2203.151823	[ "reference", "cervical", "lymph", "tbilisi", "area", "enlarged", "nodes", "region", "cells", "major" ]	[ { "code": "6B22.Z", "title": "Olfactory reference disorder, unspecified" }, { "code": "MB26.03", "title": "Delusion of reference" }, { "code": "6B22.1", "title": "Olfactory reference disorder with poor to absent insight" }, { "code": "4B00.0Z", "title": "Neutropaenia, unspecified" }, { "code": "3B63.1Z", "title": "Acquired thrombocytosis, unspecified" }, { "code": "GA04", "title": "Cervicitis" }, { "code": "GA1Z&XA5WW1", "title": "Noninflammatory disorders of cervix uteri" }, { "code": "FB1Y", "title": "Other specified conditions associated with the spine" }, { "code": "GA04&XT5R", "title": "Acute cervicitis" }, { "code": "GA04&XT8W", "title": "Chronic cervicitis" } ]	=== ICD-11 CODES FOUND === [6B22.Z] Olfactory reference disorder, unspecified Also known as: Olfactory reference disorder, unspecified \| Olfactory reference disorder \| Delusions of malodour [MB26.03] Delusion of reference Definition: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature. Also known as: Delusion of reference [6B22.1] Olfactory reference disorder with poor to absent insight Definition: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative explanation for their experience. The lack of insight exhibited by the individual does not vary markedly as a function of anxiety level. Also known as: Olfactory reference disorder with poor to absent insight [4B00.0Z] Neutropaenia, unspecified Also known as: Neutropaenia, unspecified \| Neutropenia \| Disorders with decreased neutrophil counts \| neutropaenic disorder \| neutrophil count below reference range [3B63.1Z] Acquired thrombocytosis, unspecified Also known as: Acquired thrombocytosis, unspecified \| Acquired thrombocytosis \| Idiopathic haemorrhagic thrombocythaemia \| Essential thrombocythaemia \| primary haemorrhagic thrombocythaemia [GA04] Cervicitis Also known as: Cervicitis \| inflammation of cervix \| inflammation of cervix uteri \| Ulcer of cervix with cervicitis \| Acute cervicitis [FB1Y] Other specified conditions associated with the spine Also known as: Other specified conditions associated with the spine \| Other recurrent vertebral subluxation \| Interspinous ligament syndrome \| Spondylitis muscularis \| Posterior longitudinal ligament calcification === GRAPH WALKS === --- Walk 1 --- [6B22.Z] Olfactory reference disorder, unspecified --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --PARENT--> [?] Obsessive-compulsive or related disorders Def: Obsessive-compulsive and related disorders is a group of disorders characterised by repetitive thoughts and behaviours that are believed to share similarities in aetiology and key diagnostic validator... --- Walk 2 --- [6B22.Z] Olfactory reference disorder, unspecified --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --CHILD--> [6B22.Z] Olfactory reference disorder, unspecified --- Walk 3 --- [MB26.03] Delusion of reference Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature.... --PARENT--> [MB26.0] Delusion Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus... --CHILD--> [MB26.02] Delusion of guilt Def: A delusion involving exaggerated or inappropriate responsibility, need for punishment or retribution, or disproportionate consequences of one’s actions, such as that a minor error in the past will lea... --- Walk 4 --- [MB26.03] Delusion of reference Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature.... --PARENT--> [MB26.0] Delusion Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus... --CHILD--> [MB26.01] Delusion of being controlled Def: A delusion that involves an external force or person controlling one's feelings, impulses, thoughts, or behaviour.... --- Walk 5 --- [6B22.1] Olfactory reference disorder with poor to absent insight Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative... --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --PARENT--> [?] Obsessive-compulsive or related disorders Def: Obsessive-compulsive and related disorders is a group of disorders characterised by repetitive thoughts and behaviours that are believed to share similarities in aetiology and key diagnostic validator... --- Walk 6 --- [6B22.1] Olfactory reference disorder with poor to absent insight Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative... --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --CHILD--> [6B22.0] Olfactory reference disorder with fair to good insight Def: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true a...	[ "[6B22.Z] Olfactory reference disorder, unspecified\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --PARENT--> [?] Obsessive-compulsive or related disorders\n Def: Obsessive-compulsive and related disorders is a group of disorders characterised by repetitive thoughts and behaviours that are believed to share similarities in aetiology and key diagnostic validator...", "[6B22.Z] Olfactory reference disorder, unspecified\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --CHILD--> [6B22.Z] Olfactory reference disorder, unspecified", "[MB26.03] Delusion of reference\n Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature....\n --PARENT--> [MB26.0] Delusion\n Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus...\n --CHILD--> [MB26.02] Delusion of guilt\n Def: A delusion involving exaggerated or inappropriate responsibility, need for punishment or retribution, or disproportionate consequences of one’s actions, such as that a minor error in the past will lea...", "[MB26.03] Delusion of reference\n Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature....\n --PARENT--> [MB26.0] Delusion\n Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus...\n --CHILD--> [MB26.01] Delusion of being controlled\n Def: A delusion that involves an external force or person controlling one's feelings, impulses, thoughts, or behaviour....", "[6B22.1] Olfactory reference disorder with poor to absent insight\n Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative...\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --PARENT--> [?] Obsessive-compulsive or related disorders\n Def: Obsessive-compulsive and related disorders is a group of disorders characterised by repetitive thoughts and behaviours that are believed to share similarities in aetiology and key diagnostic validator...", "[6B22.1] Olfactory reference disorder with poor to absent insight\n Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative...\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --CHILD--> [6B22.0] Olfactory reference disorder with fair to good insight\n Def: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true a..." ]	6B22.Z	Olfactory reference disorder, unspecified	[ { "from_icd11": "6B22.Z", "icd10_code": "F428", "icd10_title": "Other obsessive-compulsive disorder" }, { "from_icd11": "3B63.1Z", "icd10_code": "D473", "icd10_title": "Essential (hemorrhagic) thrombocythemia" }, { "from_icd11": "FB1Y", "icd10_code": "M5126", "icd10_title": "Other intervertebral disc displacement, lumbar region" } ]	F428	Other obsessive-compulsive disorder
This patient is a 35-year-old male with no significant past medical history who presented to the emergency department with symptoms of “redness and swelling in his eyes associated with purulent discharge” that had failed to improve on outpatient antibiotic regimen. On further history, patient revealed that for about a year and a half, he had been experiencing grittiness and a “bulging” feeling in his eyes that he thought were due to seasonal allergies as well as loss of balance when standing or walking. His ophthalmologist had ordered an orbital CT scan that revealed retroorbital soft tissue masses. An outpatient biopsy of these masses was nondiagnostic and the patient was subsequently admitted for further evaluation. On physical exam, the patient had bilateral erythematous conjunctiva associated with exophthalmoses without any evidence of lid lag or thyromegaly. Cardiovascular and pulmonary examinations were normal. There was no hepatosplenomegaly or palpable lymphadenopathy. Laboratory values on admission were notable for leukocytosis of 21 × 10 3 /uL (nL ≤ 10 × 10 3 /uL), normal erythrocyte sedimentation rate of 10 mm/hr, elevated C-reactive protein of 2.7 mg/dL (nL < 1 mg/dL), normal thyroid stimulating hormone level of 3.13 u/IU/mL, and a normal lactate dehydrogenase level of 121. He tested negative for HIV. Flow cytometry studies performed on peripheral blood did not reveal any abnormalities.	3.835938	0.985352	sec[1]/p[0]	en	0.999997	27340583	https://doi.org/10.1155/2016/2670495	[ "that", "eyes", "associated", "outpatient", "masses", "this", "past", "emergency", "department", "redness" ]	[ { "code": "8A80.Z", "title": "Migraine, unspecified" }, { "code": "QA76", "title": "Medication or substance that is known to be an allergen without injury or harm" }, { "code": "PL13.6", "title": "Medication or substance that is known to be an allergen, as mode of injury or harm" }, { "code": "9C40.A0", "title": "Papilloedema" }, { "code": "PA6Z", "title": "Unintentional fall from unspecified height" }, { "code": "9E1Z", "title": "Diseases of the visual system, unspecified" }, { "code": "QF01.Y", "title": "Other specified acquired absence of organs" }, { "code": "LA10.Y", "title": "Other specified structural developmental anomalies of ocular globes" }, { "code": "LA10.0", "title": "Microphthalmos" }, { "code": "NA06.8D", "title": "Ocular laceration without prolapse or loss of intraocular tissue, unilateral" } ]	=== ICD-11 CODES FOUND === [8A80.Z] Migraine, unspecified Also known as: Migraine, unspecified \| Migraine [QA76] Medication or substance that is known to be an allergen without injury or harm Definition: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm. Also known as: Medication or substance that is known to be an allergen without injury or harm Excludes: Medication or substance that is known to be an allergen, as mode of injury or harm [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm Also known as: Medication or substance that is known to be an allergen, as mode of injury or harm \| medication error relating to known allergy to drug or substance \| adverse drug event relating to known allergy to drug or substance [9C40.A0] Papilloedema Definition: Optic disc swelling that results from increased intracranial pressure Also known as: Papilloedema \| Optic disc swelling that results from increased intracranial pressure Includes: Optic disc swelling that results from increased intracranial pressure [PA6Z] Unintentional fall from unspecified height Also known as: Unintentional fall from unspecified height \| fall NOS \| accidental fall \| fall causing injury that resulted in death \| fell NOS [9E1Z] Diseases of the visual system, unspecified Also known as: Diseases of the visual system, unspecified \| eye diseases NOS \| disorder of vision \| visual disorder [QF01.Y] Other specified acquired absence of organs Also known as: Other specified acquired absence of organs \| Acquired absence of part of head or neck \| Acquired absence of eye \| absence of eye \| absence of eyeball [LA10.Y] Other specified structural developmental anomalies of ocular globes Also known as: Other specified structural developmental anomalies of ocular globes \| Cyclopia \| synophthalmia \| Congenital cystic eye \| Congenital malformations of the eye [LA10.0] Microphthalmos Also known as: Microphthalmos \| globe of eye small \| Microphthalmia \| small eyeball \| Hypoplasia of eye Includes: Dysplasia of eye \| Hypoplasia of eye \| Rudimentary eye [NA06.8D] Ocular laceration without prolapse or loss of intraocular tissue, unilateral Also known as: Ocular laceration without prolapse or loss of intraocular tissue, unilateral \| Laceration of eye NOS \| penetrating eyeball injury without prolapse or loss of intraocular tissue \| Traumatic rupture of eye, unilateral \| rupture of eye, unilateral === GRAPH WALKS === --- Walk 1 --- [8A80.Z] Migraine, unspecified --PARENT--> [8A80] Migraine Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a... --EXCLUDES--> [?] Headache, not elsewhere classified Def: Headache with characteristic features suggesting that it is a unique diagnostic entity, a finding or complaint, but not fulfilling criteria for any of the headache disorders described above.... --- Walk 2 --- [8A80.Z] Migraine, unspecified --PARENT--> [8A80] Migraine Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a... --EXCLUDES--> [?] Headache, not elsewhere classified Def: Headache with characteristic features suggesting that it is a unique diagnostic entity, a finding or complaint, but not fulfilling criteria for any of the headache disorders described above.... --- Walk 3 --- [QA76] Medication or substance that is known to be an allergen without injury or harm Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm.... --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --- Walk 4 --- [QA76] Medication or substance that is known to be an allergen without injury or harm Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm.... --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --- Walk 5 --- [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm Def: Incorrect dose - too high... --- Walk 6 --- [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance --CHILD--> [PL13.2] Drug-related injury or harm in the context of correct administration or dosage, as mode of injury or harm	[ "[8A80.Z] Migraine, unspecified\n --PARENT--> [8A80] Migraine\n Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a...\n --EXCLUDES--> [?] Headache, not elsewhere classified\n Def: Headache with characteristic features suggesting that it is a unique diagnostic entity, a finding or complaint, but not fulfilling criteria for any of the headache disorders described above....", "[8A80.Z] Migraine, unspecified\n --PARENT--> [8A80] Migraine\n Def: A primary headache disorder, in most cases episodic. Disabling attacks lasting 4-72 hours are characterised by moderate or severe headache, usually accompanied by nausea, vomiting and/or photophobia a...\n --EXCLUDES--> [?] Headache, not elsewhere classified\n Def: Headache with characteristic features suggesting that it is a unique diagnostic entity, a finding or complaint, but not fulfilling criteria for any of the headache disorders described above....", "[QA76] Medication or substance that is known to be an allergen without injury or harm\n Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm....\n --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance", "[QA76] Medication or substance that is known to be an allergen without injury or harm\n Def: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm....\n --EXCLUDES--> [?] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [?] Mode of injury or harm associated with exposure to a drug, medicament or biological substance", "[PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance\n --CHILD--> [PL13.0] Overdose of substance, as mode of injury or harm\n Def: Incorrect dose - too high...", "[PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm\n --PARENT--> [PL13] Mode of injury or harm associated with exposure to a drug, medicament or biological substance\n --CHILD--> [PL13.2] Drug-related injury or harm in the context of correct administration or dosage, as mode of injury or harm" ]	8A80.Z	Migraine, unspecified	[ { "from_icd11": "8A80.Z", "icd10_code": "G43B0", "icd10_title": "Ophthalmoplegic migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43409", "icd10_title": "Hemiplegic migraine, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A0", "icd10_title": "Cyclical vomiting, in migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D0", "icd10_title": "Abdominal migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43709", "icd10_title": "Chronic migraine without aura, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A1", "icd10_title": "Cyclical vomiting, in migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43509", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43719", "icd10_title": "Chronic migraine without aura, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43501", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C0", "icd10_title": "Periodic headache syndromes in child or adult, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43401", "icd10_title": "Hemiplegic migraine, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43419", "icd10_title": "Hemiplegic migraine, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43B1", "icd10_title": "Ophthalmoplegic migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C1", "icd10_title": "Periodic headache syndromes in child or adult, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D1", "icd10_title": "Abdominal migraine, intractable" } ]	G43B0	Ophthalmoplegic migraine, not intractable
A High resolution computed tomography scan (HRCT) was performed 4 days after antibiotic therapy. It revealed soft tissue nodular infiltrates and dense consolidation in the lower lobe of the right lung. There was ground glass opacification and haze bilaterally with more prominenence in the right lower lobe . Atelactatic changes were also present right middle lobe, ligular segment and left lower lobe. There was pleural thickening bilaterally and calcified pleural plaques were noted along the diaphragmatic pleura on the left. Our experienced radiologist described these changes were most probably due to chronic infective/granulomatous disease, most probably tuberculosis (TB). In high suspicion of tuberculosis, especially since the patient was not recovering, had a family history of treated TB in the past one year and since TB is extremely common in our country, anti tuberculous therapy (ATT) was begun empirically. Figure 2 High Resolution computed tomography scan of the chest. Panel A and B show soft tissue nodular infiltrates and dense consolidation in the right lower lobe of the lung. There is ground glass opacification and haze bilaterally with more prominenence in the right lower lobe. Atelactatic changes are also present right middle lobe, ligular segment and left lower lobe. There is pleural thickening bilaterally and calcified pleural plaques are noted along the diaphragmatic pleura on the left.	3.851563	0.963379	sec[1]/p[7]	en	0.999998	25890084	https://doi.org/10.1186/s13104-015-0984-4	[ "lobe", "bilaterally", "pleural", "changes", "resolution", "computed", "tomography", "scan", "soft", "tissue" ]	[ { "code": "CB40.2", "title": "Pulmonary collapse" }, { "code": "LA75.0", "title": "Accessory lobe of lung" }, { "code": "MD41", "title": "Clinical findings on diagnostic imaging of lung" }, { "code": "LA75.1", "title": "Agenesis of lung" }, { "code": "JA8A.1", "title": "Malformation of placenta" }, { "code": "CB2Z", "title": "Pleural, diaphragm or mediastinal disorders, unspecified" }, { "code": "LA76", "title": "Structural developmental anomalies of pleura" }, { "code": "MD31", "title": "Pleurisy" }, { "code": "NB32.60", "title": "Laceration of pleura" }, { "code": "2F91.Y&XA5TT2", "title": "Neoplasms of unknown behaviour of pleura" } ]	=== ICD-11 CODES FOUND === [CB40.2] Pulmonary collapse Also known as: Pulmonary collapse \| Atelectasis \| lung collapse \| pulmonary atelectasis \| pulmonary collapse with atelectasis Includes: Atelectasis Excludes: Primary atelectasis of newborn \| tuberculous atelectasis, not confirmed \| tuberculous atelectasis, confirmed [LA75.0] Accessory lobe of lung Definition: An extra lobe of lung beyond the 3 on the right and the 2 on the left Also known as: Accessory lobe of lung \| supernumerary lung lobe \| azygos lobe of lung \| azygos lobe fissure of lung \| azygos lobe [MD41] Clinical findings on diagnostic imaging of lung Definition: Clinical findings on diagnostic imaging of lung is findings on diagnostic imaging of the lung which don't appear in normal status of the body. Diagnostic imaging refers to technologies that doctors use to look inside body for clues about a medical condition. X-rays, CT scans, nuclear medicine scans, MRI scans and ultrasound are all types of diagnostic imaging. Also known as: Clinical findings on diagnostic imaging of lung \| abnormal diagnostic imaging of lung \| Hyperinflation of lung \| Lung mass \| Pulmonary lobe mass [LA75.1] Agenesis of lung Definition: This refers to the absence or rudimentary residua of an undeveloped lung. Also known as: Agenesis of lung \| Pulmonary agenesis \| absence of lung \| aplasia of lung \| apulmonism [JA8A.1] Malformation of placenta Also known as: Malformation of placenta \| variation of placenta form \| deformity of placenta \| placental deformity \| Abnormal placenta NOS [CB2Z] Pleural, diaphragm or mediastinal disorders, unspecified Also known as: Pleural, diaphragm or mediastinal disorders, unspecified [LA76] Structural developmental anomalies of pleura Definition: Anomalies of the lining of the lung (visceral pleura) and thoracic cavity (parietal pleura) Also known as: Structural developmental anomalies of pleura \| Malformations of pleura \| anomaly of pleura \| abnormal pleura \| pleural anomaly [MD31] Pleurisy Definition: Pleurisy or Pleuritis is the medical term for inflammation of the pleura. The most common cause of pleuritis is infection, but it can also be caused by lupus, rheumatoid arthritis, and certain medicines. Pleurisy or pleuritis usually accumulates exudative pleural effusions. Also known as: Pleurisy \| pleuritis \| pleurisy NOS \| double pleurisy \| pleurisy without effusion Excludes: pleurisy with effusion [NB32.60] Laceration of pleura Also known as: Laceration of pleura === GRAPH WALKS === --- Walk 1 --- [CB40.2] Pulmonary collapse --EXCLUDES--> [?] Primary atelectasis of newborn Def: Failure of the lungs to expand after birth, as in stillborn infants or in liveborn infants who die before respiration is established... --PARENT--> [?] Respiratory disorders specific to the perinatal or neonatal period Def: A group of conditions occurring during the period of time around childbirth, especially the five months before and one month after birth which are associated with the cardiovascular or respiratory sys... --- Walk 2 --- [CB40.2] Pulmonary collapse --EXCLUDES--> [?] Primary atelectasis of newborn Def: Failure of the lungs to expand after birth, as in stillborn infants or in liveborn infants who die before respiration is established... --PARENT--> [?] Respiratory disorders specific to the perinatal or neonatal period Def: A group of conditions occurring during the period of time around childbirth, especially the five months before and one month after birth which are associated with the cardiovascular or respiratory sys... --- Walk 3 --- [LA75.0] Accessory lobe of lung Def: An extra lobe of lung beyond the 3 on the right and the 2 on the left... --PARENT--> [LA75] Structural developmental anomalies of lungs Def: Any condition caused by failure of the lungs to correctly develop during the antenatal period.... --CHILD--> [LA75.0] Accessory lobe of lung Def: An extra lobe of lung beyond the 3 on the right and the 2 on the left... --- Walk 4 --- [LA75.0] Accessory lobe of lung Def: An extra lobe of lung beyond the 3 on the right and the 2 on the left... --PARENT--> [LA75] Structural developmental anomalies of lungs Def: Any condition caused by failure of the lungs to correctly develop during the antenatal period.... --CHILD--> [LA75.0] Accessory lobe of lung Def: An extra lobe of lung beyond the 3 on the right and the 2 on the left... --- Walk 5 --- [MD41] Clinical findings on diagnostic imaging of lung Def: Clinical findings on diagnostic imaging of lung is findings on diagnostic imaging of the lung which don't appear in normal status of the body. Diagnostic imaging refers to technologies that doctors us... --PARENT--> [?] Clinical findings in the respiratory system --CHILD--> [MD40] Clinical findings in specimens from respiratory organs and thorax --- Walk 6 --- [MD41] Clinical findings on diagnostic imaging of lung Def: Clinical findings on diagnostic imaging of lung is findings on diagnostic imaging of the lung which don't appear in normal status of the body. Diagnostic imaging refers to technologies that doctors us... --PARENT--> [?] Clinical findings in the respiratory system --PARENT--> [?] Symptoms, signs or clinical findings of the respiratory system	[ "[CB40.2] Pulmonary collapse\n --EXCLUDES--> [?] Primary atelectasis of newborn\n Def: Failure of the lungs to expand after birth, as in stillborn infants or in liveborn infants who die before respiration is established...\n --PARENT--> [?] Respiratory disorders specific to the perinatal or neonatal period\n Def: A group of conditions occurring during the period of time around childbirth, especially the five months before and one month after birth which are associated with the cardiovascular or respiratory sys...", "[CB40.2] Pulmonary collapse\n --EXCLUDES--> [?] Primary atelectasis of newborn\n Def: Failure of the lungs to expand after birth, as in stillborn infants or in liveborn infants who die before respiration is established...\n --PARENT--> [?] Respiratory disorders specific to the perinatal or neonatal period\n Def: A group of conditions occurring during the period of time around childbirth, especially the five months before and one month after birth which are associated with the cardiovascular or respiratory sys...", "[LA75.0] Accessory lobe of lung\n Def: An extra lobe of lung beyond the 3 on the right and the 2 on the left...\n --PARENT--> [LA75] Structural developmental anomalies of lungs\n Def: Any condition caused by failure of the lungs to correctly develop during the antenatal period....\n --CHILD--> [LA75.0] Accessory lobe of lung\n Def: An extra lobe of lung beyond the 3 on the right and the 2 on the left...", "[LA75.0] Accessory lobe of lung\n Def: An extra lobe of lung beyond the 3 on the right and the 2 on the left...\n --PARENT--> [LA75] Structural developmental anomalies of lungs\n Def: Any condition caused by failure of the lungs to correctly develop during the antenatal period....\n --CHILD--> [LA75.0] Accessory lobe of lung\n Def: An extra lobe of lung beyond the 3 on the right and the 2 on the left...", "[MD41] Clinical findings on diagnostic imaging of lung\n Def: Clinical findings on diagnostic imaging of lung is findings on diagnostic imaging of the lung which don't appear in normal status of the body. Diagnostic imaging refers to technologies that doctors us...\n --PARENT--> [?] Clinical findings in the respiratory system\n --CHILD--> [MD40] Clinical findings in specimens from respiratory organs and thorax", "[MD41] Clinical findings on diagnostic imaging of lung\n Def: Clinical findings on diagnostic imaging of lung is findings on diagnostic imaging of the lung which don't appear in normal status of the body. Diagnostic imaging refers to technologies that doctors us...\n --PARENT--> [?] Clinical findings in the respiratory system\n --PARENT--> [?] Symptoms, signs or clinical findings of the respiratory system" ]	CB40.2	Pulmonary collapse	[ { "from_icd11": "CB40.2", "icd10_code": "J9811", "icd10_title": "Atelectasis" }, { "from_icd11": "CB40.2", "icd10_code": "J9819", "icd10_title": "Other pulmonary collapse" }, { "from_icd11": "CB40.2", "icd10_code": "J981", "icd10_title": "Pulmonary collapse" }, { "from_icd11": "LA75.0", "icd10_code": "Q331", "icd10_title": "Accessory lobe of lung" }, { "from_icd11": "MD41", "icd10_code": "R911", "icd10_title": "Solitary pulmonary nodule" }, { "from_icd11": "MD41", "icd10_code": "R91", "icd10_title": "Abnormal findings on diagnostic imaging of lung" }, { "from_icd11": "LA75.1", "icd10_code": "Q333", "icd10_title": "Agenesis of lung" }, { "from_icd11": "JA8A.1", "icd10_code": "O43123", "icd10_title": "Velamentous insertion of umbilical cord, third trimester" }, { "from_icd11": "JA8A.1", "icd10_code": "O43193", "icd10_title": "Other malformation of placenta, third trimester" }, { "from_icd11": "JA8A.1", "icd10_code": "O43122", "icd10_title": "Velamentous insertion of umbilical cord, second trimester" }, { "from_icd11": "JA8A.1", "icd10_code": "O43113", "icd10_title": "Circumvallate placenta, third trimester" }, { "from_icd11": "JA8A.1", "icd10_code": "O43192", "icd10_title": "Other malformation of placenta, second trimester" }, { "from_icd11": "JA8A.1", "icd10_code": "O43103", "icd10_title": "Malformation of placenta, unspecified, third trimester" }, { "from_icd11": "JA8A.1", "icd10_code": "O43101", "icd10_title": "Malformation of placenta, unspecified, first trimester" }, { "from_icd11": "JA8A.1", "icd10_code": "O43102", "icd10_title": "Malformation of placenta, unspecified, second trimester" } ]	J9811	Atelectasis
On the echocardiogram, she was found to have ventricular interdependence, significant respirophasic variation on the mitral valve, diastolic hepatic vein reversal, and a dilated noncollapsible inferior vena cava . She underwent a coronary angiogram, which showed nonobstructive coronary artery disease but severe pericardial calcifications . A right heart catheterization was not performed due to the echocardiographic findings that were highly suggestive of CP physiology. On CT of the chest, she was found to have severe pericardial calcifications . On cardiac MRI, she was found to have abnormal septal motion of the sigmoidization, septal bounce, and flattening during early diastole. Autoimmune workup (including an antinuclear antibody panel and rheumatoid factor) were negative along with erythrocyte sedimentation rate and C-reactive protein biomarkers. She tested negative for tuberculosis, had no cardiac surgery history, and no history of radiation. She did report a significant history of chest trauma with multiple motor vehicle accidents and blunt force trauma due to altercations. She had been trialed on nonsteroidal anti-inflammatory drugs (5-day therapy of ketorolac), as well as steroids (5-day therapy of prednisone 40 mg daily), with no relief. She successfully underwent pericardiectomy with resolution of her symptoms. Pericardial biopsy showed fibroconnective tissue with extensive calcifications.	3.978516	0.979004	sec[1]/p[1]	en	0.999996	PMC9838225	https://doi.org/10.14797/mdcvj.1183	[ "pericardial", "calcifications", "coronary", "chest", "cardiac", "septal", "trauma", "echocardiogram", "ventricular", "interdependence" ]	[ { "code": "BB2Z", "title": "Pericarditis, unspecified" }, { "code": "LA8D", "title": "Congenital pericardial anomaly" }, { "code": "BB2Y", "title": "Other specified pericarditis" }, { "code": "BB22", "title": "Constrictive pericarditis" }, { "code": "GA10.E&XA2XU0", "title": "Endometriosis of pericardium" }, { "code": "GB61.Z", "title": "Chronic kidney disease, stage unspecified" }, { "code": "FB31.Y", "title": "Other specified calcification or ossification of muscle" }, { "code": "FA37.Y", "title": "Other specified certain joint disorders, not elsewhere classified" }, { "code": "BE2Y", "title": "Other specified diseases of the circulatory system" }, { "code": "EB90.40", "title": "Dystrophic calcification of the skin of uncertain or unspecified aetiology" } ]	=== ICD-11 CODES FOUND === [BB2Z] Pericarditis, unspecified Also known as: Pericarditis, unspecified \| pericarditis NOS \| pericardial inflammation \| pericardium inflammation [LA8D] Congenital pericardial anomaly Definition: A congenital cardiovascular malformation in which there is a structural and/or functional abnormality of the pericardium. Also known as: Congenital pericardial anomaly \| malformations of pericardium \| structural developmental anomalies of the pericardium \| congenital anomaly of pericardium \| structural developmental anomaly of the pericardium [BB2Y] Other specified pericarditis Also known as: Other specified pericarditis \| Certain diseases of pericardium \| Chronic adhesive pericarditis \| adherent pericarditis \| adherent pericardium [BB22] Constrictive pericarditis Definition: Chronic fibrous pericarditis due to the presence of dense fibrous tissue between the parietal and visceral layers of pericardium and neighbouring structures. Also known as: Constrictive pericarditis \| pericarditis calculosa \| Hutinel-Pick syndrome \| chronic tamponade \| chronic pericardial constriction Includes: concretio cordis [GB61.Z] Chronic kidney disease, stage unspecified Also known as: Chronic kidney disease, stage unspecified \| Chronic kidney disease \| chronic renal failure \| chronic kidney failure \| chronic renal disease [FB31.Y] Other specified calcification or ossification of muscle Also known as: Other specified calcification or ossification of muscle \| Calcification or ossification of muscles with known aetiology \| Calcification of muscle associated with adult dermatomyositis \| Myositis ossificans traumatica \| Myositis ossificans traumatica, multiple sites [FA37.Y] Other specified certain joint disorders, not elsewhere classified Also known as: Other specified certain joint disorders, not elsewhere classified \| Calcification of joint \| Periarticular calcification \| Periarticular ossification \| Fistula of joint [BE2Y] Other specified diseases of the circulatory system Also known as: Other specified diseases of the circulatory system \| Certain specified forms of heart disease \| Cardiac disorder, unspecified \| disorder of heart NOS \| organic disease or disorder of heart [EB90.40] Dystrophic calcification of the skin of uncertain or unspecified aetiology Definition: Abnormal deposition of calcium in the skin and subcutaneous tissues of unknown (idiopathic) or unspecified cause. Also known as: Dystrophic calcification of the skin of uncertain or unspecified aetiology \| Calcinosis cutis of uncertain or unspecified aetiology \| Osteoma cutis \| Cutaneous ossification \| Subepidermal calcified nodule Includes: Calcinosis cutis === GRAPH WALKS === --- Walk 1 --- [BB2Z] Pericarditis, unspecified --PARENT--> [?] Pericarditis --CHILD--> [BB20] Acute pericarditis Def: Acute pericarditis is defined as pericardial inflammation of no more than 1 to 2 weeks duration.... --- Walk 2 --- [BB2Z] Pericarditis, unspecified --PARENT--> [?] Pericarditis --RELATED_TO--> [?] Acute rheumatic pericarditis Def: A disease of the pericardium, caused by acute rheumatic fever. This disease is characterised by fever, dry cough, rapid heart rate, fatigue, or low blood pressure. Confirmation is by echocardiography,... --- Walk 3 --- [LA8D] Congenital pericardial anomaly Def: A congenital cardiovascular malformation in which there is a structural and/or functional abnormality of the pericardium.... --PARENT--> [?] Structural developmental anomaly of heart or great vessels Def: A congenital malformation of the heart and/or great vessels or an acquired abnormality unique to the congenitally malformed heart.... --RELATED_TO--> [?] Congenital cardiac tumor, not otherwise specified Def: A congenital malformation consisting of growth of abnormal tissue within the heart.... --- Walk 4 --- [LA8D] Congenital pericardial anomaly Def: A congenital cardiovascular malformation in which there is a structural and/or functional abnormality of the pericardium.... --PARENT--> [?] Structural developmental anomaly of heart or great vessels Def: A congenital malformation of the heart and/or great vessels or an acquired abnormality unique to the congenitally malformed heart.... --RELATED_TO--> [?] Congenital great vessel related acquired abnormality Def: Any postnatal pathological change in form or function of the heart and/or great vessels consequent to the presence of congenital cardiovascular disease.... --- Walk 5 --- [BB2Y] Other specified pericarditis --PARENT--> [?] Pericarditis --RELATED_TO--> [?] Pneumopericardium originating in the perinatal period Def: Presence of air in the pericardial cavity usually from tracking of free air from ruptured alveolar ducts along the perivascular sheaths of pulmonary blood vessels, or rupture of subpleural bleb... --- Walk 6 --- [BB2Y] Other specified pericarditis --PARENT--> [?] Pericarditis --RELATED_TO--> [?] Acute rheumatic pericarditis Def: A disease of the pericardium, caused by acute rheumatic fever. This disease is characterised by fever, dry cough, rapid heart rate, fatigue, or low blood pressure. Confirmation is by echocardiography,...	[ "[BB2Z] Pericarditis, unspecified\n --PARENT--> [?] Pericarditis\n --CHILD--> [BB20] Acute pericarditis\n Def: Acute pericarditis is defined as pericardial inflammation of no more than 1 to 2 weeks duration....", "[BB2Z] Pericarditis, unspecified\n --PARENT--> [?] Pericarditis\n --RELATED_TO--> [?] Acute rheumatic pericarditis\n Def: A disease of the pericardium, caused by acute rheumatic fever. This disease is characterised by fever, dry cough, rapid heart rate, fatigue, or low blood pressure. Confirmation is by echocardiography,...", "[LA8D] Congenital pericardial anomaly\n Def: A congenital cardiovascular malformation in which there is a structural and/or functional abnormality of the pericardium....\n --PARENT--> [?] Structural developmental anomaly of heart or great vessels\n Def: A congenital malformation of the heart and/or great vessels or an acquired abnormality unique to the congenitally malformed heart....\n --RELATED_TO--> [?] Congenital cardiac tumor, not otherwise specified\n Def: A congenital malformation consisting of growth of abnormal tissue within the heart....", "[LA8D] Congenital pericardial anomaly\n Def: A congenital cardiovascular malformation in which there is a structural and/or functional abnormality of the pericardium....\n --PARENT--> [?] Structural developmental anomaly of heart or great vessels\n Def: A congenital malformation of the heart and/or great vessels or an acquired abnormality unique to the congenitally malformed heart....\n --RELATED_TO--> [?] Congenital great vessel related acquired abnormality\n Def: Any postnatal pathological change in form or function of the heart and/or great vessels consequent to the presence of congenital cardiovascular disease....", "[BB2Y] Other specified pericarditis\n --PARENT--> [?] Pericarditis\n --RELATED_TO--> [?] Pneumopericardium originating in the perinatal period\n Def: Presence of air in the pericardial cavity usually from tracking of free air from ruptured alveolar ducts along the perivascular sheaths of pulmonary blood vessels, or rupture of subpleural bleb...", "[BB2Y] Other specified pericarditis\n --PARENT--> [?] Pericarditis\n --RELATED_TO--> [?] Acute rheumatic pericarditis\n Def: A disease of the pericardium, caused by acute rheumatic fever. This disease is characterised by fever, dry cough, rapid heart rate, fatigue, or low blood pressure. Confirmation is by echocardiography,..." ]	BB2Z	Pericarditis, unspecified	[ { "from_icd11": "BB2Z", "icd10_code": "I314", "icd10_title": "Cardiac tamponade" }, { "from_icd11": "BB2Z", "icd10_code": "I319", "icd10_title": "Disease of pericardium, unspecified" }, { "from_icd11": "BB2Z", "icd10_code": "I310", "icd10_title": "Chronic adhesive pericarditis" }, { "from_icd11": "BB2Z", "icd10_code": "I318", "icd10_title": "Other specified diseases of pericardium" }, { "from_icd11": "BB2Z", "icd10_code": "I31", "icd10_title": "Other diseases of pericardium" }, { "from_icd11": "LA8D", "icd10_code": "Q248", "icd10_title": "Other specified congenital malformations of heart" }, { "from_icd11": "BB22", "icd10_code": "I311", "icd10_title": "Chronic constrictive pericarditis" }, { "from_icd11": "GB61.Z", "icd10_code": "N183", "icd10_title": "Chronic kidney disease, stage 3 (moderate)" }, { "from_icd11": "GB61.Z", "icd10_code": "N189", "icd10_title": "Chronic kidney disease, unspecified" }, { "from_icd11": "GB61.Z", "icd10_code": "N250", "icd10_title": "Renal osteodystrophy" }, { "from_icd11": "GB61.Z", "icd10_code": "N18", "icd10_title": "Chronic kidney disease (CKD)" }, { "from_icd11": "EB90.40", "icd10_code": "L943", "icd10_title": "Sclerodactyly" }, { "from_icd11": "EB90.40", "icd10_code": "L949", "icd10_title": "Localized connective tissue disorder, unspecified" }, { "from_icd11": "EB90.40", "icd10_code": "L942", "icd10_title": "Calcinosis cutis" }, { "from_icd11": "EB90.40", "icd10_code": "L94", "icd10_title": "Other localized connective tissue disorders" } ]	I314	Cardiac tamponade
It was decided to implant a permanent dual-chamber endocardial pacemaker with selective stimulation of the left bundle branch, considering the congenital heart disease, the anatomy of the conduction system, and the surgical correction. Through the left axillary vein, an atrial electrode was placed in the right atrial appendage, where adequate capture was evidenced. Using the C315 sheath, the SelectSecure MRI SureScan 3830 electrode was implanted guided by electrograms. After three turns, it was possible to show left bundle branch potential and a notch in the descending limb of the S wave in V1 ( Supplementary Material S3 ). Two more turns were given to the electrode without presenting ventricular extrasystoles with right bundle branch morphology and observing notch displacement in V1 and V2 to the right, finally showing in V1 and V2 with r′ ; the position was confirmed using contrast. Tests performed showed a capture threshold of 1.1 V/1 ms and unipolar impedance of 756 Ω. The final ECG showed a narrow QRS (80 ms), with normal axes and a right bundle branch image in V1 . Total fluoroscopy time was 31.9 min and 1,579 mGy. An echocardiogram was performed 24 h after PM implantation with left bundle branch stimulation. It demonstrated interventricular synchrony, amelioration of LV dilation ( Z -Score +2.19), and a significant improvement of left ventricular systolic function as LVEF increased to 31.8%.	4.109375	0.883789	sec[1]/sec[2]/p[2]	en	0.999998	PMC10192706	https://doi.org/10.3389/fped.2023.1160335	[ "bundle", "branch", "electrode", "stimulation", "atrial", "capture", "using", "turns", "notch", "ventricular" ]	[ { "code": "BC63.5", "title": "Nonspecific intraventricular conduction delay" }, { "code": "BC63.5&XK2J", "title": "Complete bundle branch block" }, { "code": "BC63.5&XK06", "title": "Incomplete bundle branch block" }, { "code": "BC63.4Z", "title": "Left bundle branch block, fascicle unspecified" }, { "code": "BC63.3", "title": "Right bundle branch block" }, { "code": "5C51.3", "title": "Glycogen storage disease" }, { "code": "LA8B.2Z", "title": "Congenital anomaly of aorta or its branches, unspecified" }, { "code": "5C50.D0", "title": "Maple-syrup-urine disease" }, { "code": "LA8B.1", "title": "Congenital anomaly of pulmonary arterial tree" }, { "code": "KA42.3", "title": "Monitoring injury of scalp of newborn" } ]	=== ICD-11 CODES FOUND === [BC63.5] Nonspecific intraventricular conduction delay Definition: Disorder of the atrioventricular conduction system characterised by a prolonged QRS duration (QRS duration greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and greater than 80 ms in children less than 8 years of age) without criteria for right or left bundle branch block. Also known as: Nonspecific intraventricular conduction delay \| intraventricular block NOS \| intraventricular block \| intraventricular conduction defect \| Bundle branch block [BC63.4Z] Left bundle branch block, fascicle unspecified Also known as: Left bundle branch block, fascicle unspecified \| Left bundle branch block \| Incomplete left bundle branch block [BC63.3] Right bundle branch block Definition: Disorder of the atrioventricular conduction system characterised by prolonged QRS duration (greater than or equal to 120 ms in adults, greater than 100 ms in children ages 4 to 16 years, and greater than 90 ms in children less than 4 years of age), rsr, rsR, or rSR in leads V1 or V2, S wave of greater duration than R wave (or greater than 40 ms in leads I and V6 in adults) Also known as: Right bundle branch block \| Complete right bundle branch block \| Incomplete right bundle branch block Includes: Incomplete right bundle branch block [5C51.3] Glycogen storage disease Definition: The term Glycogen storage disease characterises a group of heterogeneous diseases resulting from defects in the process of glycogen synthesis or breakdown within muscles, liver, and other cell types. Also known as: Glycogen storage disease \| Glycogenosis \| GSD - [Glycogen storage disease] \| glycogen thesaurismosis \| diffuse glycogenosis Includes: Glycogen storage disease due to LAMP-2 deficiency \| Glycogen storage disease due to glycogen debranching enzyme deficiency \| Glycogen storage disease due to muscle glycogen phosphorylase deficiency [LA8B.2Z] Congenital anomaly of aorta or its branches, unspecified Also known as: Congenital anomaly of aorta or its branches, unspecified \| Congenital anomaly of aorta or its branches [5C50.D0] Maple-syrup-urine disease Definition: Maple syrup urine disease (MSUD) is a disorder of branched-chain amino acids metabolism. Four forms are described. The early onset classic form manifests after birth by lethargy, poor feeding and neurological signs of intoxication. Clinical course without treatment is characterised by deepening coma with maple syrup odour of urine. Subacute MSUD manifests later with encephalopathy, mental disability, major hypotonia, opisthotonus and cerebral atrophy with severe outcome. The intermittent form of Also known as: Maple-syrup-urine disease \| Ketoacid decarboxylase deficiency \| Branched chain ketoaciduria \| Oxoacid decarboxylase deficiency \| branched chain ketoacid dehydrogenase deficiency [LA8B.1] Congenital anomaly of pulmonary arterial tree Definition: A congenital cardiovascular malformation of the pulmonary trunk (main pulmonary artery) and/or branch pulmonary arteries (right, left, and ramifications). Also known as: Congenital anomaly of pulmonary arterial tree \| Aberrant pulmonary artery \| abnormal origin of pulmonary artery \| Anomaly of pulmonary artery \| congenital malposition of pulmonary artery Includes: Aberrant pulmonary artery \| Anomaly of pulmonary artery [KA42.3] Monitoring injury of scalp of newborn Definition: Injuries to the scalp from use of intrapartum fetal monitoring devices including injury following fetal blood sampling. Also known as: Monitoring injury of scalp of newborn \| Injury to scalp of newborn due to sampling incision \| Sampling incision of scalp of newborn \| Injury to scalp of newborn due to scalp clip or electrode \| fetal scalp electrode injury === GRAPH WALKS === --- Walk 1 --- [BC63.5] Nonspecific intraventricular conduction delay Def: Disorder of the atrioventricular conduction system characterised by a prolonged QRS duration (QRS duration greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and great... --PARENT--> [BC63] Conduction disorders Def: Any abnormal alteration of atrio-ventricular conduction.... --CHILD--> [BC63.1] Atrioventricular block, second degree Def: Disorder of the atrioventricular conduction system in which some but not all atrial impulses fail to propagate to the ventricles. Electrocardiographically, some P waves are not followed by a QRS compl... --- Walk 2 --- [BC63.5] Nonspecific intraventricular conduction delay Def: Disorder of the atrioventricular conduction system characterised by a prolonged QRS duration (QRS duration greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and great... --PARENT--> [BC63] Conduction disorders Def: Any abnormal alteration of atrio-ventricular conduction.... --CHILD--> [BC63.0] Atrioventricular block, first degree Def: Disorder of the atrioventricular conduction system in which the PR interval is greater than the 97th percentile for age or > 200 ms in adults... --- Walk 3 --- [BC63.4Z] Left bundle branch block, fascicle unspecified --PARENT--> [BC63.4] Left bundle branch block Def: Disorder of the atrioventricular conduction system in which the QRS duration is greater than or equal to 120 ms in adults, greater than 100 ms in children 4 to 16 years of age, and greater than 90 ms ... --CHILD--> [BC63.40] Left anterior fascicular block Def: Disorder of the atrioventricular conduction system characterised by left axis deviation for age (frontal plane axis between -45° and -90°), qR pattern in lead aVL, R-peak time in lead aVL of 45 ms or ... --- Walk 4 --- [BC63.4Z] Left bundle branch block, fascicle unspecified --PARENT--> [BC63.4] Left bundle branch block Def: Disorder of the atrioventricular conduction system in which the QRS duration is greater than or equal to 120 ms in adults, greater than 100 ms in children 4 to 16 years of age, and greater than 90 ms ... --CHILD--> [BC63.41] Left posterior fascicular block Def: Disorder of the atrioventricular conduction system characterised by right axis deviation for age (between 90° and 180° in adults), with a qR pattern in inferior leads, rS pattern in leftward leads (I ... --- Walk 5 --- [BC63.3] Right bundle branch block Def: Disorder of the atrioventricular conduction system characterised by prolonged QRS duration (greater than or equal to 120 ms in adults, greater than 100 ms in children ages 4 to 16 years, and greater t... --PARENT--> [BC63] Conduction disorders Def: Any abnormal alteration of atrio-ventricular conduction.... --RELATED_TO--> [?] Congenital heart block Def: Heart block of any degree that is present at birth... --- Walk 6 --- [BC63.3] Right bundle branch block Def: Disorder of the atrioventricular conduction system characterised by prolonged QRS duration (greater than or equal to 120 ms in adults, greater than 100 ms in children ages 4 to 16 years, and greater t... --PARENT--> [BC63] Conduction disorders Def: Any abnormal alteration of atrio-ventricular conduction.... --CHILD--> [BC63.2] Complete atrioventricular block Def: Disorder of the atrioventricular conduction system in which there is failure of all atrial impulses to propagate to the ventricle...	[ "[BC63.5] Nonspecific intraventricular conduction delay\n Def: Disorder of the atrioventricular conduction system characterised by a prolonged QRS duration (QRS duration greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and great...\n --PARENT--> [BC63] Conduction disorders\n Def: Any abnormal alteration of atrio-ventricular conduction....\n --CHILD--> [BC63.1] Atrioventricular block, second degree\n Def: Disorder of the atrioventricular conduction system in which some but not all atrial impulses fail to propagate to the ventricles. Electrocardiographically, some P waves are not followed by a QRS compl...", "[BC63.5] Nonspecific intraventricular conduction delay\n Def: Disorder of the atrioventricular conduction system characterised by a prolonged QRS duration (QRS duration greater than 110 ms in adults, greater than 90 ms in children 8 to 16 years of age, and great...\n --PARENT--> [BC63] Conduction disorders\n Def: Any abnormal alteration of atrio-ventricular conduction....\n --CHILD--> [BC63.0] Atrioventricular block, first degree\n Def: Disorder of the atrioventricular conduction system in which the PR interval is greater than the 97th percentile for age or > 200 ms in adults...", "[BC63.4Z] Left bundle branch block, fascicle unspecified\n --PARENT--> [BC63.4] Left bundle branch block\n Def: Disorder of the atrioventricular conduction system in which the QRS duration is greater than or equal to 120 ms in adults, greater than 100 ms in children 4 to 16 years of age, and greater than 90 ms ...\n --CHILD--> [BC63.40] Left anterior fascicular block\n Def: Disorder of the atrioventricular conduction system characterised by left axis deviation for age (frontal plane axis between -45° and -90°), qR pattern in lead aVL, R-peak time in lead aVL of 45 ms or ...", "[BC63.4Z] Left bundle branch block, fascicle unspecified\n --PARENT--> [BC63.4] Left bundle branch block\n Def: Disorder of the atrioventricular conduction system in which the QRS duration is greater than or equal to 120 ms in adults, greater than 100 ms in children 4 to 16 years of age, and greater than 90 ms ...\n --CHILD--> [BC63.41] Left posterior fascicular block\n Def: Disorder of the atrioventricular conduction system characterised by right axis deviation for age (between 90° and 180° in adults), with a qR pattern in inferior leads, rS pattern in leftward leads (I ...", "[BC63.3] Right bundle branch block\n Def: Disorder of the atrioventricular conduction system characterised by prolonged QRS duration (greater than or equal to 120 ms in adults, greater than 100 ms in children ages 4 to 16 years, and greater t...\n --PARENT--> [BC63] Conduction disorders\n Def: Any abnormal alteration of atrio-ventricular conduction....\n --RELATED_TO--> [?] Congenital heart block\n Def: Heart block of any degree that is present at birth...", "[BC63.3] Right bundle branch block\n Def: Disorder of the atrioventricular conduction system characterised by prolonged QRS duration (greater than or equal to 120 ms in adults, greater than 100 ms in children ages 4 to 16 years, and greater t...\n --PARENT--> [BC63] Conduction disorders\n Def: Any abnormal alteration of atrio-ventricular conduction....\n --CHILD--> [BC63.2] Complete atrioventricular block\n Def: Disorder of the atrioventricular conduction system in which there is failure of all atrial impulses to propagate to the ventricle..." ]	BC63.5	Nonspecific intraventricular conduction delay	[ { "from_icd11": "BC63.5", "icd10_code": "I454", "icd10_title": "Nonspecific intraventricular block" }, { "from_icd11": "BC63.4Z", "icd10_code": "I447", "icd10_title": "Left bundle-branch block, unspecified" }, { "from_icd11": "BC63.4Z", "icd10_code": "I44", "icd10_title": "Atrioventricular and left bundle-branch block" }, { "from_icd11": "BC63.3", "icd10_code": "I4510", "icd10_title": "Unspecified right bundle-branch block" }, { "from_icd11": "BC63.3", "icd10_code": "I4519", "icd10_title": "Other right bundle-branch block" }, { "from_icd11": "BC63.3", "icd10_code": "I450", "icd10_title": "Right fascicular block" }, { "from_icd11": "BC63.3", "icd10_code": "I451", "icd10_title": "Other and unspecified right bundle-branch block" }, { "from_icd11": "5C51.3", "icd10_code": "E7401", "icd10_title": "von Gierke disease" }, { "from_icd11": "5C51.3", "icd10_code": "E7404", "icd10_title": "McArdle disease" }, { "from_icd11": "5C51.3", "icd10_code": "E7402", "icd10_title": "Pompe disease" }, { "from_icd11": "5C51.3", "icd10_code": "E7403", "icd10_title": "Cori disease" }, { "from_icd11": "5C51.3", "icd10_code": "E7409", "icd10_title": "Other glycogen storage disease" }, { "from_icd11": "5C51.3", "icd10_code": "E7400", "icd10_title": "Glycogen storage disease, unspecified" }, { "from_icd11": "5C51.3", "icd10_code": "E740", "icd10_title": "Glycogen storage disease" }, { "from_icd11": "LA8B.2Z", "icd10_code": "Q2543", "icd10_title": "Congenital aneurysm of aorta" } ]	I454	Nonspecific intraventricular block
Posttransplant lymphoproliferative disorder (PTLD) is a recognized complication arising in allograft recipients treated with immunosuppressive drugs with a reported incidence of 1-2% in renal transplant patients . PTLD may occur, even many years after transplantation, and is comprised of a histologic spectrum, ranging from hyperplastic-appearing lesions to frank non-Hodgkin's lymphoma or multiple myeloma histology and recently T-cell lymphomas. Herein we present a case of histiocytic sarcoma arising in the native kidney of a patient with a history of remote renal transplantation. Histiocytic sarcoma is a rare and often aggressive neoplasm with only a limited number of reported cases. To the best of our knowledge there are only 3 case reports on a kidney transplant recipient [ 2 – 4 ]. The current epidemiology estimates that less than one percent of tumors presenting in soft tissue or lymph nodes can be defined as histiocytic sarcoma (HS) . The pathognomonic attributes of this tumor remain elusive even though several studies have been published in attempts to characterize reliable phenotypic and genotypic features including associations with germ cell tumors and with malignant lymphoma . Our case along with the three other published case reports of HS in renal transplant recipients raised the possibility of HS being one manifestation of a late posttransplantation lymphoproliferative disorder (PTLD).	4.234375	0.687012	sec[0]/p[0]	en	0.999997	27795864	https://doi.org/10.1155/2016/3591050	[ "ptld", "renal", "transplant", "histiocytic", "sarcoma", "lymphoproliferative", "arising", "recipients", "even", "transplantation" ]	[ { "code": "2B32.Z", "title": "Immunodeficiency-associated lymphoproliferative disorders, unspecified" }, { "code": "GC2Z&XA6KU8", "title": "Disease of kidney, not elsewhere classified" }, { "code": "GB6Z", "title": "Kidney failure, unspecified" }, { "code": "LB30.1", "title": "Renal dysplasia" }, { "code": "NB92.0Y", "title": "Other specified injury of kidney" }, { "code": "LB30.7", "title": "Ectopic or pelvic kidney" }, { "code": "QB63.Z", "title": "Presence of transplanted organ or tissue, unspecified" }, { "code": "QB63.Y", "title": "Presence of other transplanted organ or tissue" }, { "code": "NE84", "title": "Failure or rejection of transplanted organs or tissues" }, { "code": "QB63.4", "title": "Presence of transplanted skin" } ]	=== ICD-11 CODES FOUND === [2B32.Z] Immunodeficiency-associated lymphoproliferative disorders, unspecified Also known as: Immunodeficiency-associated lymphoproliferative disorders, unspecified \| Immunodeficiency-associated lymphoproliferative disorders \| PTLD - [Post transplant lymphoproliferative disorder] [GB6Z] Kidney failure, unspecified Also known as: Kidney failure, unspecified \| nontraumatic kidney injury \| renal failure NOS \| kidney block \| renal impairment NOS [LB30.1] Renal dysplasia Definition: A condition characterised by abnormal development of one or both kidneys. Also known as: Renal dysplasia \| congenital renal dysplasia \| dysplasia of kidney \| dysplastic kidney \| Primary renal dysplasia Excludes: Autosomal dominant polycystic kidney disease [NB92.0Y] Other specified injury of kidney Also known as: Other specified injury of kidney \| Injury of kidney without open wound into cavity \| Injury of kidney with open wound into cavity \| Haematoma of kidney \| traumatic perirenal haematoma [LB30.7] Ectopic or pelvic kidney Definition: A birth defect characterised by an abnormally positioned kidney; may be asymptomatic or result in urine blockage, infection or kidney stones Also known as: Ectopic or pelvic kidney \| Congenital displaced kidney \| congenital misplaced kidney \| congenital malposition of kidney \| congenital prolapsed kidney Includes: Congenital displaced kidney \| Malrotation of kidney [QB63.Z] Presence of transplanted organ or tissue, unspecified Also known as: Presence of transplanted organ or tissue, unspecified \| Presence of transplanted organ or tissue \| transplanted organ or tissue status \| organ or tissue replaced by heterogenous or homogenous transplant \| organ transplant [QB63.Y] Presence of other transplanted organ or tissue Also known as: Presence of other transplanted organ or tissue \| Presence of transplanted heart and lungs \| heart and lungs transplant status \| Presence of transplanted intestine \| intestinal transplant [NE84] Failure or rejection of transplanted organs or tissues Also known as: Failure or rejection of transplanted organs or tissues \| organ transplant rejection \| transplant failure \| transplant rejection \| Bone-marrow transplant rejection [QB63.4] Presence of transplanted skin Also known as: Presence of transplanted skin \| skin transplant status \| autogenous skin transplant status \| skin transplantation === GRAPH WALKS === --- Walk 1 --- [2B32.Z] Immunodeficiency-associated lymphoproliferative disorders, unspecified --PARENT--> [2B32] Immunodeficiency-associated lymphoproliferative disorders Def: Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of... --CHILD--> [2B32.0] Post-transplant lymphoproliferative disorder, early lesion Def: A lymphoproliferative disorder arising as a result of post-transplant immunosuppression therapy. It is characterised by the lack of tissue destruction and the architectural preservation of the involve... --- Walk 2 --- [2B32.Z] Immunodeficiency-associated lymphoproliferative disorders, unspecified --PARENT--> [2B32] Immunodeficiency-associated lymphoproliferative disorders Def: Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of... --CHILD--> [2B32.1] Reactive plasmacytic hyperplasia --- Walk 3 --- [GB6Z] Kidney failure, unspecified --PARENT--> [?] Kidney failure Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ... --RELATED_TO--> [?] Renal failure following abortion, ectopic or molar pregnancy --- Walk 4 --- [GB6Z] Kidney failure, unspecified --PARENT--> [?] Kidney failure Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ... --CHILD--> [GB6Z] Kidney failure, unspecified --- Walk 5 --- [LB30.1] Renal dysplasia Def: A condition characterised by abnormal development of one or both kidneys.... --EXCLUDES--> [?] Autosomal dominant polycystic kidney disease Def: Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and d... --PARENT--> [?] Chronic tubulo-interstitial nephritis associated with familial or genetic diseases --- Walk 6 --- [LB30.1] Renal dysplasia Def: A condition characterised by abnormal development of one or both kidneys.... --PARENT--> [LB30] Structural developmental anomalies of kidneys Def: Any condition caused by failure of the kidneys to correctly develop during the antenatal period.... --CHILD--> [LB30.2] Congenital single renal cyst Def: A single cyst in a kidney, noted in utero or from birth. No other structural abnormality of the kidney or urinary tract noted....	[ "[2B32.Z] Immunodeficiency-associated lymphoproliferative disorders, unspecified\n --PARENT--> [2B32] Immunodeficiency-associated lymphoproliferative disorders\n Def: Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of...\n --CHILD--> [2B32.0] Post-transplant lymphoproliferative disorder, early lesion\n Def: A lymphoproliferative disorder arising as a result of post-transplant immunosuppression therapy. It is characterised by the lack of tissue destruction and the architectural preservation of the involve...", "[2B32.Z] Immunodeficiency-associated lymphoproliferative disorders, unspecified\n --PARENT--> [2B32] Immunodeficiency-associated lymphoproliferative disorders\n Def: Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of...\n --CHILD--> [2B32.1] Reactive plasmacytic hyperplasia", "[GB6Z] Kidney failure, unspecified\n --PARENT--> [?] Kidney failure\n Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ...\n --RELATED_TO--> [?] Renal failure following abortion, ectopic or molar pregnancy", "[GB6Z] Kidney failure, unspecified\n --PARENT--> [?] Kidney failure\n Def: Inability of the kidneys to adequately filter the blood of waste products, with a lower than normal glomerular filtration rate (GFR). Can be abrupt and potentially reversible (acute kidney injury) or ...\n --CHILD--> [GB6Z] Kidney failure, unspecified", "[LB30.1] Renal dysplasia\n Def: A condition characterised by abnormal development of one or both kidneys....\n --EXCLUDES--> [?] Autosomal dominant polycystic kidney disease\n Def: Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and d...\n --PARENT--> [?] Chronic tubulo-interstitial nephritis associated with familial or genetic diseases", "[LB30.1] Renal dysplasia\n Def: A condition characterised by abnormal development of one or both kidneys....\n --PARENT--> [LB30] Structural developmental anomalies of kidneys\n Def: Any condition caused by failure of the kidneys to correctly develop during the antenatal period....\n --CHILD--> [LB30.2] Congenital single renal cyst\n Def: A single cyst in a kidney, noted in utero or from birth. No other structural abnormality of the kidney or urinary tract noted...." ]	2B32.Z	Immunodeficiency-associated lymphoproliferative disorders, unspecified	[ { "from_icd11": "2B32.Z", "icd10_code": "D479", "icd10_title": "Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified" }, { "from_icd11": "GB6Z", "icd10_code": "N19", "icd10_title": "Unspecified kidney failure" }, { "from_icd11": "GB6Z", "icd10_code": "N17-N19", "icd10_title": "" }, { "from_icd11": "GB6Z", "icd10_code": "N17", "icd10_title": "Acute kidney failure" }, { "from_icd11": "LB30.1", "icd10_code": "Q614", "icd10_title": "Renal dysplasia" }, { "from_icd11": "LB30.7", "icd10_code": "Q632", "icd10_title": "Ectopic kidney" }, { "from_icd11": "LB30.7", "icd10_code": "Q63", "icd10_title": "Other congenital malformations of kidney" }, { "from_icd11": "QB63.Z", "icd10_code": "Z9484", "icd10_title": "Stem cells transplant status" }, { "from_icd11": "QB63.Z", "icd10_code": "Z9481", "icd10_title": "Bone marrow transplant status" }, { "from_icd11": "QB63.Z", "icd10_code": "Z9489", "icd10_title": "Other transplanted organ and tissue status" }, { "from_icd11": "QB63.Z", "icd10_code": "Z9483", "icd10_title": "Pancreas transplant status" }, { "from_icd11": "QB63.Z", "icd10_code": "Z9482", "icd10_title": "Intestine transplant status" }, { "from_icd11": "QB63.Z", "icd10_code": "Z949", "icd10_title": "Transplanted organ and tissue status, unspecified" }, { "from_icd11": "QB63.Z", "icd10_code": "Z94", "icd10_title": "Transplanted organ and tissue status" }, { "from_icd11": "QB63.Z", "icd10_code": "Z943", "icd10_title": "Heart and lungs transplant status" } ]	D479	Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified
A 68-year-old asymptomatic man was referred to our hospital for evaluation because of an irregularity in the gastric body, which was detected during a medical examination. His blood tests revealed no abnormalities, except for an elevated HbA1c level of 6.9%. Endoscopy and upper gastrointestinal series showed not only a type 0-IIc and 0-III gastric tumor (25 mm) with an ulceration at the posterior wall of the middle third of the stomach but also a type 0-IIc tumor (right, half-circumferential; 30 mm) in the lower third of the esophagus . The biopsies of the tumors revealed squamous cell carcinoma in the thoracic lower esophagus (cT1bN0M0, cStageIA) and well- and moderately differentiated adenocarcinoma of the stomach (T1bN0M0, cStageIA). A computed tomography (CT) scan showed no primary tumor in the stomach or esophagus, no lymph node metastasis, and no tumors in other organs such as the liver and lungs. Colonoscopy and CT scan were performed to evaluate the colon and the patency of the middle colic vessels. Two polyps were detected in the ascending colon, and endoscopic polypectomy was performed 2 days prior to tumor resection. Figure 1 Findings of the upper gastrointestinal series. (a,b) Types 0-IIc and 0-III tumors are shown, with ulceration at the posterior wall of the middle third of the stomach. (c,d) A type 0-IIc tumor (right half-circumferential) is shown in the lower third of the esophagus.	3.78125	0.982422	sec[1]/p[0]	en	0.999995	26943380	https://doi.org/10.1186/s40792-015-0018-4	[ "tumor", "stomach", "esophagus", "type", "middle", "tumors", "gastric", "gastrointestinal", "series", "ulceration" ]	[ { "code": "2F9Z", "title": "Neoplasms of unknown behaviour of unspecified site" }, { "code": "ME61", "title": "Subcutaneous swelling, mass or lump of uncertain or unspecified nature" }, { "code": "2E6Z", "title": "Carcinoma in situ of unspecified site" }, { "code": "2F91.1", "title": "Neoplasms of unknown behaviour of trachea, bronchus or lung" }, { "code": "2F92", "title": "Neoplasms of unknown behaviour of skin" }, { "code": "DA4Z", "title": "Diseases of stomach, unspecified" }, { "code": "DA60.Z", "title": "Gastric ulcer, unspecified" }, { "code": "QF01.Y", "title": "Other specified acquired absence of organs" }, { "code": "LB13.Z", "title": "Structural developmental anomalies of stomach, unspecified" }, { "code": "DA42.73", "title": "Chronic atrophic gastritis of unknown aetiology" } ]	=== ICD-11 CODES FOUND === [2F9Z] Neoplasms of unknown behaviour of unspecified site Also known as: Neoplasms of unknown behaviour of unspecified site \| neoplasia \| neoplasm growth NOS \| tumour of unspecified site \| tumourlet of unspecified site [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Definition: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature Also known as: Subcutaneous swelling, mass or lump of uncertain or unspecified nature \| localised swelling, mass or lump of skin and subcutaneous tissue \| localised subcutaneous nodules \| subcutaneous nodules \| superficial subcutaneous nodules Excludes: localized adiposity \| mass and lump: breast \| enlarged lymph nodes [2E6Z] Carcinoma in situ of unspecified site Also known as: Carcinoma in situ of unspecified site \| carcinoma in situ of unspecified site \| carcinoma in situ NOS \| carcinoma in situ \| in situ neoplasm [2F91.1] Neoplasms of unknown behaviour of trachea, bronchus or lung Also known as: Neoplasms of unknown behaviour of trachea, bronchus or lung \| trachea, bronchus or lung tumour NOS \| Intravascular bronchial alveolar tumour of unspecified site \| Bronchial adenoma of unknown behaviour of unspecified site \| Intravascular bronchial alveolar tumour unknown behaviour of unspecified site [2F92] Neoplasms of unknown behaviour of skin Also known as: Neoplasms of unknown behaviour of skin \| skin tumour NOS [DA4Z] Diseases of stomach, unspecified Also known as: Diseases of stomach, unspecified \| disorder of stomach \| gastropathy NOS \| gastric disease NOS \| stomach disease NOS [DA60.Z] Gastric ulcer, unspecified Also known as: Gastric ulcer, unspecified \| Gastric ulcer \| stomach ulcer \| Cushings ulcer \| cushing's ulcer of stomach [QF01.Y] Other specified acquired absence of organs Also known as: Other specified acquired absence of organs \| Acquired absence of part of head or neck \| Acquired absence of eye \| absence of eye \| absence of eyeball [LB13.Z] Structural developmental anomalies of stomach, unspecified Also known as: Structural developmental anomalies of stomach, unspecified \| Structural developmental anomalies of stomach \| Malformations of stomach [DA42.73] Chronic atrophic gastritis of unknown aetiology Definition: Persistent or recurrent inflammation of the gastric mucosa with atrophy leading to decreased hydrochloric acid concentration in the gastric juice. Atrophic gastritis frequently progresses from chronic gastritis. Also known as: Chronic atrophic gastritis of unknown aetiology \| Gastric atrophy \| atrophic gastritis \| AG - [atrophic gastritis] \| CAG - [chronic atrophic gastritis] Includes: Gastric atrophy === GRAPH WALKS === --- Walk 1 --- [2F9Z] Neoplasms of unknown behaviour of unspecified site --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues --CHILD--> [2F92] Neoplasms of unknown behaviour of skin --- Walk 2 --- [2F9Z] Neoplasms of unknown behaviour of unspecified site --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues --CHILD--> [2F90] Neoplasms of unknown behaviour of oral cavity or digestive organs --- Walk 3 --- [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature... --EXCLUDES--> [?] Breast lump or mass female --PARENT--> [?] Symptoms, signs or clinical findings involving the female genital system --- Walk 4 --- [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature... --EXCLUDES--> [?] Breast lump or mass female --PARENT--> [?] Symptoms, signs or clinical findings involving the female genital system --- Walk 5 --- [2E6Z] Carcinoma in situ of unspecified site --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues --CHILD--> [2E60] Carcinoma in situ of oral cavity, oesophagus or stomach --- Walk 6 --- [2E6Z] Carcinoma in situ of unspecified site --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues --CHILD--> [2E62] Carcinoma in situ of middle ear or respiratory system	[ "[2F9Z] Neoplasms of unknown behaviour of unspecified site\n --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues\n --CHILD--> [2F92] Neoplasms of unknown behaviour of skin", "[2F9Z] Neoplasms of unknown behaviour of unspecified site\n --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues\n --CHILD--> [2F90] Neoplasms of unknown behaviour of oral cavity or digestive organs", "[ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature\n Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature...\n --EXCLUDES--> [?] Breast lump or mass female\n --PARENT--> [?] Symptoms, signs or clinical findings involving the female genital system", "[ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature\n Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature...\n --EXCLUDES--> [?] Breast lump or mass female\n --PARENT--> [?] Symptoms, signs or clinical findings involving the female genital system", "[2E6Z] Carcinoma in situ of unspecified site\n --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues\n --CHILD--> [2E60] Carcinoma in situ of oral cavity, oesophagus or stomach", "[2E6Z] Carcinoma in situ of unspecified site\n --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues\n --CHILD--> [2E62] Carcinoma in situ of middle ear or respiratory system" ]	2F9Z	Neoplasms of unknown behaviour of unspecified site	[ { "from_icd11": "2F9Z", "icd10_code": "D487", "icd10_title": "Neoplasm of uncertain behavior of other specified sites" }, { "from_icd11": "2F9Z", "icd10_code": "D482", "icd10_title": "Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system" }, { "from_icd11": "2F9Z", "icd10_code": "D37-D48", "icd10_title": "" }, { "from_icd11": "2F9Z", "icd10_code": "D377", "icd10_title": "" }, { "from_icd11": "2F9Z", "icd10_code": "D48", "icd10_title": "Neoplasm of uncertain behavior of other and unspecified sites" }, { "from_icd11": "2F9Z", "icd10_code": "D489", "icd10_title": "Neoplasm of uncertain behavior, unspecified" }, { "from_icd11": "ME61", "icd10_code": "R2240", "icd10_title": "Localized swelling, mass and lump, unspecified lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2232", "icd10_title": "Localized swelling, mass and lump, left upper limb" }, { "from_icd11": "ME61", "icd10_code": "R2242", "icd10_title": "Localized swelling, mass and lump, left lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2231", "icd10_title": "Localized swelling, mass and lump, right upper limb" }, { "from_icd11": "ME61", "icd10_code": "R2241", "icd10_title": "Localized swelling, mass and lump, right lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2233", "icd10_title": "Localized swelling, mass and lump, upper limb, bilateral" }, { "from_icd11": "ME61", "icd10_code": "R2243", "icd10_title": "Localized swelling, mass and lump, lower limb, bilateral" }, { "from_icd11": "ME61", "icd10_code": "R2230", "icd10_title": "Localized swelling, mass and lump, unspecified upper limb" }, { "from_icd11": "ME61", "icd10_code": "R220", "icd10_title": "Localized swelling, mass and lump, head" } ]	D487	Neoplasm of uncertain behavior of other specified sites
A 15-year-old Latino male with no family history of lung cancer was diagnosed with primary ALK-positive adenocarcinoma of the lung . Upon presentation, the patient was found to have multiple metastases to the brain and was treated with surgical resection for a single posterior fossa lesion followed by whole brain radiation. Multiple recurrences of the disease were followed by 10 courses of SRS for 47 metastatic lesions. Whole brain radiotherapy was delivered with opposed lateral beams and consisted of 35 Gy in 14 fractions. Linear accelerator-based SRS was performed via multi-isocenter techniques, using 4-5 cone-based circular arcs per lesion, except for two lesions that were treated with five dynamic conformal arcs. The patient was immobilized using a bivalve mask for frameless image-guided radiosurgery using a Novalis linear accelerator. The median dose to the peripheral margin of the lesions was 20 Gy. The whole brain tissue, minus the volume of SRS-treated lesions, was contoured. The integral dose (Joules or Gy-Kg) to the normal whole brain tissue was then calculated using the dose volume histograms (DVH) for both the whole brain radiotherapy and the SRS treatments. This was divided by the mass of normal brain in Kg to give the units of Gy. All planning was done in the BrainLab 4.5.2 with SRS performed on the Novalis linear accelerator with ExacTrac © 6D Robotic and stereoscopic image guidance.	4.101563	0.943359	sec[1]/p[0]	en	0.999995	26858917	https://doi.org/10.7759/cureus.436	[ "brain", "whole", "lesions", "using", "treated", "linear", "accelerator", "lung", "multiple", "lesion" ]	[ { "code": "8E7Y", "title": "Other specified diseases of the nervous system" }, { "code": "LA05.Z", "title": "Cerebral structural developmental anomalies, unspecified" }, { "code": "1D00.Z", "title": "Infectious encephalitis, unspecified" }, { "code": "LA00.0Z", "title": "Anencephaly, unspecified" }, { "code": "NA07.3Y", "title": "Other specified diffuse brain injury" }, { "code": "LD43.1", "title": "Mosaic monosomy of autosome" }, { "code": "NE60", "title": "Harmful effects of drugs, medicaments or biological substances, not elsewhere classified" }, { "code": "LD40.Y", "title": "Other specified complete trisomies of the autosomes" }, { "code": "PL11.3", "title": "Foreign body accidentally left in body, as mode of injury or harm" }, { "code": "QB20", "title": "Blood donor" } ]	=== ICD-11 CODES FOUND === [8E7Y] Other specified diseases of the nervous system Also known as: Other specified diseases of the nervous system \| Circumscribed brain atrophy \| circumscribed cerebral atrophy \| atrophic lobar sclerosis \| atrophic lobar brain sclerosis [LA05.Z] Cerebral structural developmental anomalies, unspecified Also known as: Cerebral structural developmental anomalies, unspecified \| Cerebral structural developmental anomalies \| Malformations of brain \| brain abnormality NOS \| brain deformity NOS [1D00.Z] Infectious encephalitis, unspecified Also known as: Infectious encephalitis, unspecified \| Infectious encephalitis, not elsewhere classified \| encephalitis NOS \| acute encephalitis NOS \| acute brain inflammation [LA00.0Z] Anencephaly, unspecified Also known as: Anencephaly, unspecified \| Anencephaly \| anencephalic monster \| anencephalus \| brain absence [NA07.3Y] Other specified diffuse brain injury Also known as: Other specified diffuse brain injury \| Brain contusion \| Cerebral contusion NOS \| Diffuse cortex contusion \| diffuse cortical contusion [LD43.1] Mosaic monosomy of autosome Definition: Any disease caused by embryonic fusion or loss of an autosome early in embryonic development, resulting in a subset of cells in the body having only one of a pair of autosomes. Also known as: Mosaic monosomy of autosome \| whole chromosome monosomy, mosaicism [NE60] Harmful effects of drugs, medicaments or biological substances, not elsewhere classified Also known as: Harmful effects of drugs, medicaments or biological substances, not elsewhere classified \| drugs, medicaments or biological substances, toxicity not elsewhere classified \| adverse drug effects \| drug reaction NOS \| drug allergy NOS Excludes: Alcohol intoxication \| pathological drug intoxication \| hypersensitivity reaction to correctly administered drug [LD40.Y] Other specified complete trisomies of the autosomes Also known as: Other specified complete trisomies of the autosomes \| Other complete trisomies \| entire chromosome trisomy, meiotic nondisjunction \| Other trisomy mosaicism \| Whole chromosome trisomy, mosaicism disorder [PL11.3] Foreign body accidentally left in body, as mode of injury or harm Definition: A foreign body is any solid material not normally found in the human body. It is accidentally left in the body if there was no specific intention to keep it in the body, either because it was indicated for medical purposes or because it was unsafe to retrieve. Also known as: Foreign body accidentally left in body, as mode of injury or harm \| foreign body accidentally left in body during procedure \| foreign body accidentally left in body during intervention \| foreign body accidentally left in body during surgical operation \| sponge accidentally left in body during surgical and medical care Excludes: Foreign body accidentally left in body without injury or harm [QB20] Blood donor Definition: Blood donor is a human being who is a source of blood for the purpose of transfusion. Also known as: Blood donor \| donor whole blood \| Stem cell donor \| Lymphocytes donor \| Platelets donor === GRAPH WALKS === --- Walk 1 --- [8E7Y] Other specified diseases of the nervous system --PARENT--> [08] Diseases of the nervous system Def: This is a group of conditions characterised as being in or associated with the nervous system.... --CHILD--> [?] Multiple sclerosis or other white matter disorders Def: This is a group of conditions involving demyelination, damage to the myelin sheath which protects nerve axons and is responsible for neurotransmission.... --- Walk 2 --- [8E7Y] Other specified diseases of the nervous system --PARENT--> [08] Diseases of the nervous system Def: This is a group of conditions characterised as being in or associated with the nervous system.... --CHILD--> [?] Movement disorders Def: This is a group of involuntary movement disorders.... --- Walk 3 --- [LA05.Z] Cerebral structural developmental anomalies, unspecified --PARENT--> [LA05] Cerebral structural developmental anomalies Def: Any condition caused by failure of the brain to correctly develop during the antenatal period.... --EXCLUDES--> [?] Encephalocele --- Walk 4 --- [LA05.Z] Cerebral structural developmental anomalies, unspecified --PARENT--> [LA05] Cerebral structural developmental anomalies Def: Any condition caused by failure of the brain to correctly develop during the antenatal period.... --CHILD--> [LA05.2] Holoprosencephaly Def: Holoprosencephaly is a brain malformation resulting from incomplete cleavage of the prosencephalon, occurring between the 18th and the 28th day of gestation and affecting both the forebrain and the fa... --- Walk 5 --- [1D00.Z] Infectious encephalitis, unspecified --PARENT--> [1D00] Infectious encephalitis, not elsewhere classified Def: A disease of the brain, caused by an infection.... --CHILD--> [1D00.1] Fungal encephalitis --- Walk 6 --- [1D00.Z] Infectious encephalitis, unspecified --PARENT--> [1D00] Infectious encephalitis, not elsewhere classified Def: A disease of the brain, caused by an infection.... --CHILD--> [1D00.1] Fungal encephalitis	[ "[8E7Y] Other specified diseases of the nervous system\n --PARENT--> [08] Diseases of the nervous system\n Def: This is a group of conditions characterised as being in or associated with the nervous system....\n --CHILD--> [?] Multiple sclerosis or other white matter disorders\n Def: This is a group of conditions involving demyelination, damage to the myelin sheath which protects nerve axons and is responsible for neurotransmission....", "[8E7Y] Other specified diseases of the nervous system\n --PARENT--> [08] Diseases of the nervous system\n Def: This is a group of conditions characterised as being in or associated with the nervous system....\n --CHILD--> [?] Movement disorders\n Def: This is a group of involuntary movement disorders....", "[LA05.Z] Cerebral structural developmental anomalies, unspecified\n --PARENT--> [LA05] Cerebral structural developmental anomalies\n Def: Any condition caused by failure of the brain to correctly develop during the antenatal period....\n --EXCLUDES--> [?] Encephalocele", "[LA05.Z] Cerebral structural developmental anomalies, unspecified\n --PARENT--> [LA05] Cerebral structural developmental anomalies\n Def: Any condition caused by failure of the brain to correctly develop during the antenatal period....\n --CHILD--> [LA05.2] Holoprosencephaly\n Def: Holoprosencephaly is a brain malformation resulting from incomplete cleavage of the prosencephalon, occurring between the 18th and the 28th day of gestation and affecting both the forebrain and the fa...", "[1D00.Z] Infectious encephalitis, unspecified\n --PARENT--> [1D00] Infectious encephalitis, not elsewhere classified\n Def: A disease of the brain, caused by an infection....\n --CHILD--> [1D00.1] Fungal encephalitis", "[1D00.Z] Infectious encephalitis, unspecified\n --PARENT--> [1D00] Infectious encephalitis, not elsewhere classified\n Def: A disease of the brain, caused by an infection....\n --CHILD--> [1D00.1] Fungal encephalitis" ]	8E7Y	Other specified diseases of the nervous system	[ { "from_icd11": "LA05.Z", "icd10_code": "Q048", "icd10_title": "Other specified congenital malformations of brain" }, { "from_icd11": "LA05.Z", "icd10_code": "Q043", "icd10_title": "Other reduction deformities of brain" }, { "from_icd11": "LA05.Z", "icd10_code": "Q049", "icd10_title": "Congenital malformation of brain, unspecified" }, { "from_icd11": "LA05.Z", "icd10_code": "Q04", "icd10_title": "Other congenital malformations of brain" }, { "from_icd11": "1D00.Z", "icd10_code": "G0490", "icd10_title": "Encephalitis and encephalomyelitis, unspecified" }, { "from_icd11": "1D00.Z", "icd10_code": "G0491", "icd10_title": "Myelitis, unspecified" }, { "from_icd11": "1D00.Z", "icd10_code": "G0430", "icd10_title": "Acute necrotizing hemorrhagic encephalopathy, unspecified" }, { "from_icd11": "1D00.Z", "icd10_code": "G0431", "icd10_title": "Postinfectious acute necrotizing hemorrhagic encephalopathy" }, { "from_icd11": "1D00.Z", "icd10_code": "G0439", "icd10_title": "Other acute necrotizing hemorrhagic encephalopathy" }, { "from_icd11": "1D00.Z", "icd10_code": "G0481", "icd10_title": "Other encephalitis and encephalomyelitis" }, { "from_icd11": "1D00.Z", "icd10_code": "G0489", "icd10_title": "Other myelitis" }, { "from_icd11": "1D00.Z", "icd10_code": "G04", "icd10_title": "Encephalitis, myelitis and encephalomyelitis" }, { "from_icd11": "1D00.Z", "icd10_code": "G048", "icd10_title": "Other encephalitis, myelitis and encephalomyelitis" }, { "from_icd11": "LA00.0Z", "icd10_code": "Q000", "icd10_title": "Anencephaly" }, { "from_icd11": "LD43.1", "icd10_code": "Q921", "icd10_title": "Whole chromosome trisomy, mosaicism (mitotic nondisjunction)" } ]	Q048	Other specified congenital malformations of brain
A 6-year-old girl presented with a history of road traffic accident 4 years ago, causing trauma to the spinal cord. Soon after the trauma, paralysis of both lower limbs and hands was noticed by her parents. The child underwent extensive rehabilitation leading to complete recovery of her upper limbs, but developed a plateau in her recovery phase below the level of injury. On detailed assessment prior to the cell therapy, she exhibited neurological features like hypotonia and hyporeflexia in bilateral lower limbs. Strength of grade 5 in bilateral upper limbs and grade 0 in bilateral lower limbs was recorded. Total sensory loss below D10 level was present. Urinary incontinence was reported with poor urine control. Magnetic resonance imaging (MRI) showed focal myelomalacia from C7 to D1 in the form of focal atrophy of the cord extending from C7 to D1 with altered signals at these levels; see Figure 1 . Functionally, she was partially dependent on her mother for activities of daily living (ADL), mainly mobility. She was able to stand and walk with a walker and Hip Knee Ankle Foot Orthosis (HKAFO) with difficulty and many compensatory strategies. Trunk control was poor in standing. The patient underwent two doses of cell therapy with a gap of 6 months between the two. She scored 82 out of 126 on Functional Independence Measure (FIM). On American Spinal Injury Association (ASIA) scale, she was at level A.	3.962891	0.98291	sec[1]/sec[0]/p[0]	en	0.999997	24744950	https://doi.org/10.1155/2014/404207	[ "limbs", "trauma", "spinal", "cord", "recovery", "injury", "cell", "grade", "poor", "control" ]	[ { "code": "ND56.1", "title": "Open wound of unspecified body region" }, { "code": "LB9Z", "title": "Structural developmental anomalies of the skeleton, unspecified" }, { "code": "FB56.6", "title": "Other specified soft tissue disorders" }, { "code": "5B51&XS25", "title": "Severe wasting in infants, children or adolescents" }, { "code": "ND55", "title": "Other injuries of leg, level unspecified" }, { "code": "ND56.Z", "title": "Unspecified injury to unspecified part of trunk, limb or body region" }, { "code": "ND37", "title": "Unspecified multiple injuries" }, { "code": "NB91.Y&XA9607", "title": "Injury of intestine" }, { "code": "ND56.4", "title": "Injury of nerve of unspecified body region" }, { "code": "NF0A.Z", "title": "Early complications of trauma, not elsewhere classified" } ]	=== ICD-11 CODES FOUND === [ND56.1] Open wound of unspecified body region Also known as: Open wound of unspecified body region \| cut NOS \| open wound NOS \| penetrating wound NOS \| Puncture wound with foreign body unspecified body region Excludes: Traumatic amputations involving multiple body regions \| Open wounds involving multiple body regions \| traumatic amputation NOS [LB9Z] Structural developmental anomalies of the skeleton, unspecified Also known as: Structural developmental anomalies of the skeleton, unspecified \| Abnormal bone development \| skeletal anomaly NOS [FB56.6] Other specified soft tissue disorders Also known as: Other specified soft tissue disorders \| Fat necrosis \| fatty necrosis \| Profichet's disease \| Sloughing of fascia [ND55] Other injuries of leg, level unspecified Also known as: Other injuries of leg, level unspecified \| other injuries of lower limb, level unspecified \| Superficial injury of leg, level unspecified \| Abrasion of leg, level unspecified \| Contusion of leg, level unspecified Excludes: Fracture of leg, level unspecified \| Injuries involving multiple body regions [ND56.Z] Unspecified injury to unspecified part of trunk, limb or body region Also known as: Unspecified injury to unspecified part of trunk, limb or body region \| Injury of unspecified body region \| injury NOS \| trauma NOS \| traumatic injury NOS [ND37] Unspecified multiple injuries Also known as: Unspecified multiple injuries \| multiple trauma NOS \| multiple traumatic injuries \| multiple sites of injury \| multiple system injury Excludes: injury NOS [ND56.4] Injury of nerve of unspecified body region Also known as: Injury of nerve of unspecified body region \| injuries to nerves, nerve plexuses and roots \| injury to nerves, unspecified site \| nerve damage NOS \| Injury of nerve NOS Excludes: multiple injuries of nerves NOS [NF0A.Z] Early complications of trauma, not elsewhere classified Also known as: Early complications of trauma, not elsewhere classified \| Certain early complications of trauma, not elsewhere classified \| early trauma complications \| early complication of trauma \| trauma complications === GRAPH WALKS === --- Walk 1 --- [ND56.1] Open wound of unspecified body region --EXCLUDES--> [?] Traumatic amputation of unspecified body region --CHILD--> [?] Traumatic amputation of limb --- Walk 2 --- [ND56.1] Open wound of unspecified body region --EXCLUDES--> [?] Traumatic amputations involving multiple body regions --EXCLUDES--> [?] Open wounds involving multiple body regions --- Walk 3 --- [LB9Z] Structural developmental anomalies of the skeleton, unspecified --PARENT--> [?] Structural developmental anomalies of the skeleton Def: A deformation established before birth of an anatomical structure of one or more bones.... --CHILD--> [LB72] Structural developmental anomalies of shoulder girdle Def: Any condition caused by failure of the shoulder girdle to correctly develop during the antenatal period.... --- Walk 4 --- [LB9Z] Structural developmental anomalies of the skeleton, unspecified --PARENT--> [?] Structural developmental anomalies of the skeleton Def: A deformation established before birth of an anatomical structure of one or more bones.... --CHILD--> [LB70] Structural developmental anomalies of cranium Def: Any condition caused by failure of the cranium to correctly develop during the antenatal period.... --- Walk 5 --- [FB56.6] Other specified soft tissue disorders --PARENT--> [FB56] Specified soft tissue disorders, not elsewhere classified Def: This is a group of other disorders, which are not classified elsewhere, affecting tissues that connect, support, or surround other structures and organs of the body, not being bone.... --EXCLUDES--> [?] Radiculopathy --- Walk 6 --- [FB56.6] Other specified soft tissue disorders --PARENT--> [FB56] Specified soft tissue disorders, not elsewhere classified Def: This is a group of other disorders, which are not classified elsewhere, affecting tissues that connect, support, or surround other structures and organs of the body, not being bone.... --EXCLUDES--> [?] Radiculopathy	[ "[ND56.1] Open wound of unspecified body region\n --EXCLUDES--> [?] Traumatic amputation of unspecified body region\n --CHILD--> [?] Traumatic amputation of limb", "[ND56.1] Open wound of unspecified body region\n --EXCLUDES--> [?] Traumatic amputations involving multiple body regions\n --EXCLUDES--> [?] Open wounds involving multiple body regions", "[LB9Z] Structural developmental anomalies of the skeleton, unspecified\n --PARENT--> [?] Structural developmental anomalies of the skeleton\n Def: A deformation established before birth of an anatomical structure of one or more bones....\n --CHILD--> [LB72] Structural developmental anomalies of shoulder girdle\n Def: Any condition caused by failure of the shoulder girdle to correctly develop during the antenatal period....", "[LB9Z] Structural developmental anomalies of the skeleton, unspecified\n --PARENT--> [?] Structural developmental anomalies of the skeleton\n Def: A deformation established before birth of an anatomical structure of one or more bones....\n --CHILD--> [LB70] Structural developmental anomalies of cranium\n Def: Any condition caused by failure of the cranium to correctly develop during the antenatal period....", "[FB56.6] Other specified soft tissue disorders\n --PARENT--> [FB56] Specified soft tissue disorders, not elsewhere classified\n Def: This is a group of other disorders, which are not classified elsewhere, affecting tissues that connect, support, or surround other structures and organs of the body, not being bone....\n --EXCLUDES--> [?] Radiculopathy", "[FB56.6] Other specified soft tissue disorders\n --PARENT--> [FB56] Specified soft tissue disorders, not elsewhere classified\n Def: This is a group of other disorders, which are not classified elsewhere, affecting tissues that connect, support, or surround other structures and organs of the body, not being bone....\n --EXCLUDES--> [?] Radiculopathy" ]	ND56.1	Open wound of unspecified body region	[ { "from_icd11": "ND56.1", "icd10_code": "T141", "icd10_title": "" }, { "from_icd11": "LB9Z", "icd10_code": "Q8789", "icd10_title": "Other specified congenital malformation syndromes, not elsewhere classified" }, { "from_icd11": "LB9Z", "icd10_code": "Q8781", "icd10_title": "Alport syndrome" }, { "from_icd11": "LB9Z", "icd10_code": "Q742", "icd10_title": "Other congenital malformations of lower limb(s), including pelvic girdle" }, { "from_icd11": "LB9Z", "icd10_code": "Q749", "icd10_title": "Unspecified congenital malformation of limb(s)" }, { "from_icd11": "LB9Z", "icd10_code": "Q740", "icd10_title": "Other congenital malformations of upper limb(s), including shoulder girdle" }, { "from_icd11": "LB9Z", "icd10_code": "Q741", "icd10_title": "Congenital malformation of knee" }, { "from_icd11": "LB9Z", "icd10_code": "Q875", "icd10_title": "Other congenital malformation syndromes with other skeletal changes" }, { "from_icd11": "LB9Z", "icd10_code": "Q748", "icd10_title": "Other specified congenital malformations of limb(s)" }, { "from_icd11": "LB9Z", "icd10_code": "Q89", "icd10_title": "Other congenital malformations, not elsewhere classified" }, { "from_icd11": "LB9Z", "icd10_code": "Q65-Q79", "icd10_title": "" }, { "from_icd11": "LB9Z", "icd10_code": "Q73", "icd10_title": "Reduction defects of unspecified limb" }, { "from_icd11": "LB9Z", "icd10_code": "Q730", "icd10_title": "Congenital absence of unspecified limb(s)" }, { "from_icd11": "LB9Z", "icd10_code": "Q731", "icd10_title": "Phocomelia, unspecified limb(s)" }, { "from_icd11": "LB9Z", "icd10_code": "Q74", "icd10_title": "Other congenital malformations of limb(s)" } ]	T141
On referral to our hospital, there were prominent motor (overall neuropathy limitation scale [ONLS]: arm score, 4; leg score, 5) and sensory deficits (neuropathy total symptom score-6 [NTSS-6]: aching pain score, 3.66). Physical examination showed hepatosplenomegaly, generalized lymphadenopathy, sporadic hemangioma across his trunk and skin hyperpigmentation. Laboratory studies revealed: IgG-λ monoclonal protein (detected by serum immunofixation, but not measurable on serum protein electrophoresis), thrombocytosis (371 × 10 9 /L; reference range, 100–300 × 10 9 /L), hypothyroidism (thyrotropin 6.6 μU/mL; reference range, 0.4–4.0 μU/mL), and hyperprolactinemia (22 ng/mL; reference range, 5–20 ng/mL). The cerebrospinal fluid study showed elevated protein (0.9 g/L, reference range, 0–0.4 g/L) and pleocytosis (8 × 10 6 cells/L, reference range, 0–3 × 10 6 cells/L). Bone marrow aspirate revealed 0.5% plasma cells with normal morphology (reference range, 0–1.5%). No signs of extravascular volume overload were noted. Osteosclerosis was not seen on x-ray. The clinical constellation suggested a diagnosis of POEMS syndrome. However, the characteristic acute polyneuropathy was atypical, as the median duration from disease onset to inability to walk in POEMS patients was 9 months. 3 To reach a diagnosis, we measured the serum level of vascular endothelial growth factor (VEGF), which was elevated dramatically .	4.128906	0.930664	sec[0]/sec[0]/p[1]	en	0.999998	27100445	https://doi.org/10.1097/MD.0000000000003453	[ "reference", "range", "score", "protein", "serum", "cells", "neuropathy", "poems", "referral", "prominent" ]	[ { "code": "6B22.Z", "title": "Olfactory reference disorder, unspecified" }, { "code": "MB26.03", "title": "Delusion of reference" }, { "code": "6B22.1", "title": "Olfactory reference disorder with poor to absent insight" }, { "code": "4B00.0Z", "title": "Neutropaenia, unspecified" }, { "code": "3B63.1Z", "title": "Acquired thrombocytosis, unspecified" }, { "code": "QA00.6Y", "title": "Other specified examination of eyes or vision" }, { "code": "MA14.1C", "title": "Raised antibody titre" }, { "code": "BD11.1", "title": "Left ventricular failure with mid range ejection fraction" }, { "code": "MB20.1&XC87", "title": "Glasgow Coma Scale, eyes opening, never" }, { "code": "KD30.0", "title": "Birth depression with 5 minute Apgar score 0-3" } ]	=== ICD-11 CODES FOUND === [6B22.Z] Olfactory reference disorder, unspecified Also known as: Olfactory reference disorder, unspecified \| Olfactory reference disorder \| Delusions of malodour [MB26.03] Delusion of reference Definition: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature. Also known as: Delusion of reference [6B22.1] Olfactory reference disorder with poor to absent insight Definition: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative explanation for their experience. The lack of insight exhibited by the individual does not vary markedly as a function of anxiety level. Also known as: Olfactory reference disorder with poor to absent insight [4B00.0Z] Neutropaenia, unspecified Also known as: Neutropaenia, unspecified \| Neutropenia \| Disorders with decreased neutrophil counts \| neutropaenic disorder \| neutrophil count below reference range [3B63.1Z] Acquired thrombocytosis, unspecified Also known as: Acquired thrombocytosis, unspecified \| Acquired thrombocytosis \| Idiopathic haemorrhagic thrombocythaemia \| Essential thrombocythaemia \| primary haemorrhagic thrombocythaemia [QA00.6Y] Other specified examination of eyes or vision Also known as: Other specified examination of eyes or vision \| No Impairment of Contrast vision \| Normal colour vision \| No Impairment of Dark adaptation \| No diplopia [MA14.1C] Raised antibody titre Also known as: Raised antibody titre \| antibody titre above reference range \| high antibody titre \| increased antibody titre Excludes: isoimmunization, in pregnancy affecting fetus or newborn [BD11.1] Left ventricular failure with mid range ejection fraction Also known as: Left ventricular failure with mid range ejection fraction \| HFmEF - [heart failure with mid range ejection fraction] \| Left ventricular failure with mid range ejection fraction due to cardiomyopathy \| Left ventricular failure with mid range ejection fraction due to coronary artery disease \| Left ventricular failure with mid range ejection fraction due to myocarditis [KD30.0] Birth depression with 5 minute Apgar score 0-3 Definition: A condition characterised by cardiorespiratory and neurological depression, defined as an Apgar score between 0 to 3 at 5 minutes following birth. Also known as: Birth depression with 5 minute Apgar score 0-3 === GRAPH WALKS === --- Walk 1 --- [6B22.Z] Olfactory reference disorder, unspecified --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --CHILD--> [6B22.0] Olfactory reference disorder with fair to good insight Def: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true a... --- Walk 2 --- [6B22.Z] Olfactory reference disorder, unspecified --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --CHILD--> [6B22.Z] Olfactory reference disorder, unspecified --- Walk 3 --- [MB26.03] Delusion of reference Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature.... --PARENT--> [MB26.0] Delusion Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus... --CHILD--> [MB26.00] Bizarre delusion Def: A delusion that involves a phenomenon that would be regarded as physically impossible within the person's cultural context.... --- Walk 4 --- [MB26.03] Delusion of reference Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature.... --PARENT--> [MB26.0] Delusion Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus... --CHILD--> [MB26.00] Bizarre delusion Def: A delusion that involves a phenomenon that would be regarded as physically impossible within the person's cultural context.... --- Walk 5 --- [6B22.1] Olfactory reference disorder with poor to absent insight Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative... --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --CHILD--> [6B22.1] Olfactory reference disorder with poor to absent insight Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative... --- Walk 6 --- [6B22.1] Olfactory reference disorder with poor to absent insight Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative... --PARENT--> [6B22] Olfactory reference disorder Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl... --CHILD--> [6B22.0] Olfactory reference disorder with fair to good insight Def: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true a...	[ "[6B22.Z] Olfactory reference disorder, unspecified\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --CHILD--> [6B22.0] Olfactory reference disorder with fair to good insight\n Def: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true a...", "[6B22.Z] Olfactory reference disorder, unspecified\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --CHILD--> [6B22.Z] Olfactory reference disorder, unspecified", "[MB26.03] Delusion of reference\n Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature....\n --PARENT--> [MB26.0] Delusion\n Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus...\n --CHILD--> [MB26.00] Bizarre delusion\n Def: A delusion that involves a phenomenon that would be regarded as physically impossible within the person's cultural context....", "[MB26.03] Delusion of reference\n Def: A delusion that events, objects, or other people in the person's immediate environment have a particular and unusual personal significance, usually of a negative or pejorative nature....\n --PARENT--> [MB26.0] Delusion\n Def: A belief that is demonstrably untrue or not shared by others, usually based on incorrect inference about external reality. The belief is firmly held with conviction and is not, or is only briefly, sus...\n --CHILD--> [MB26.00] Bizarre delusion\n Def: A delusion that involves a phenomenon that would be regarded as physically impossible within the person's cultural context....", "[6B22.1] Olfactory reference disorder with poor to absent insight\n Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative...\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --CHILD--> [6B22.1] Olfactory reference disorder with poor to absent insight\n Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative...", "[6B22.1] Olfactory reference disorder with poor to absent insight\n Def: All definitional requirements of olfactory reference disorder are met. Most or all of the time, the individual is convinced that the disorder-specific beliefs are true and cannot accept an alternative...\n --PARENT--> [6B22] Olfactory reference disorder\n Def: Olfactory Reference Disorder is characterised by persistent preoccupation with the belief that one is emitting a perceived foul or offensive body odour or breath that is either unnoticeable or only sl...\n --CHILD--> [6B22.0] Olfactory reference disorder with fair to good insight\n Def: All definitional requirements of olfactory reference disorder are met. Much of the time, the individual is able to entertain the possibility that his or her disorder-specific beliefs may not be true a..." ]	6B22.Z	Olfactory reference disorder, unspecified	[ { "from_icd11": "6B22.Z", "icd10_code": "F428", "icd10_title": "Other obsessive-compulsive disorder" }, { "from_icd11": "3B63.1Z", "icd10_code": "D473", "icd10_title": "Essential (hemorrhagic) thrombocythemia" }, { "from_icd11": "MA14.1C", "icd10_code": "R760", "icd10_title": "Raised antibody titer" }, { "from_icd11": "KD30.0", "icd10_code": "P210", "icd10_title": "" } ]	F428	Other obsessive-compulsive disorder
The patient was positioned prone in a halo ring after induction of general anesthesia. At the time of prone positioning, under lateral fluoroscopic guidance, we set the craniovertebral angles that had been optimized prior to surgery. We incised the skin along the marked median nuchal line from the external occipital protuberance to immediately above the seventh cervical (C7) spinous process and detached the posterior muscle group. A resin-made occipital bone was formed in accordance with the defective part of the occipital bone. Just before curing, the occipital bone plate and screws to be used for posterior fusion of the craniovertebral junction were also embedded together in resin. The resin-made occipital bone was placed in the defect's position and anchored with a titanium plate. We performed left-sided occipital cervical fusion by connecting vertebral arch pedicle screws with the occipital bone plate that had been secured to the resin-made occipital bone. On the right side, this occipital bone plate was immobilized with screws of C2 and C3 lateral mass at the remaining area of occipital bone. We harvested the iliac crest bone and grafted it onto the tip of the decorticalized spinous process of the C2 vertebra and the dorsal part of the occipital bone. The spongy bone was used in order to avoid creating dead space. The grafted bone was fixed by an ultrahigh molecular weight polyethylene cable .	3.970703	0.914063	sec[1]/sec[2]/p[0]	en	0.999998	27800203	https://doi.org/10.1155/2016/8634831	[ "bone", "occipital", "resin", "plate", "screws", "prone", "craniovertebral", "that", "cervical", "spinous" ]	[ { "code": "FC0Z", "title": "Diseases of the musculoskeletal system or connective tissue, unspecified" }, { "code": "FB84.Z", "title": "Osteomyelitis or osteitis, unspecified" }, { "code": "FB80.Z", "title": "Disorder of bone density or structure, unspecified" }, { "code": "FB86.11", "title": "Hypertrophy of bone" }, { "code": "FB86.1Z", "title": "Bone hyperplasias, unspecified" }, { "code": "LA01", "title": "Cephalocele" }, { "code": "NA0Z&XA7JE5", "title": "Occipital scalp injury" }, { "code": "LD28.2", "title": "Genetically-determined cutis laxa" }, { "code": "NA02.1A&XA33W1", "title": "Fracture of occiput without further specification" }, { "code": "NA07.Z", "title": "Intracranial injury, unspecified" } ]	=== ICD-11 CODES FOUND === [FC0Z] Diseases of the musculoskeletal system or connective tissue, unspecified Also known as: Diseases of the musculoskeletal system or connective tissue, unspecified \| bone disease NOS \| bone disorder NOS \| bone lesion NOS \| musculoskeletal complications NOS [FB84.Z] Osteomyelitis or osteitis, unspecified Also known as: Osteomyelitis or osteitis, unspecified \| Osteomyelitis or osteitis \| bone inflammation \| bone ulcer \| bone inflammatory disease [FB80.Z] Disorder of bone density or structure, unspecified Also known as: Disorder of bone density or structure, unspecified \| Certain specified disorders of bone density or structure [FB86.11] Hypertrophy of bone Also known as: Hypertrophy of bone \| bone thickening \| periosteum thickening \| Infantile cortical hyperostoses \| Post traumatic subperiosteal ossification [FB86.1Z] Bone hyperplasias, unspecified Also known as: Bone hyperplasias, unspecified \| Bone hyperplasias [LA01] Cephalocele Definition: A condition caused by failure of the skull to correctly close during the antenatal period. This condition is characterised by herniation of the meninges. This condition may present with herniation of brain, or developmental delay. Confirmation is through observation of herniated meninges by imaging. Also known as: Cephalocele \| Craniocele \| Cranial meningocele \| Encephalocele \| Cranium bifidum [LD28.2] Genetically-determined cutis laxa Also known as: Genetically-determined cutis laxa \| Autosomal recessive cutis laxa \| Autosomal recessive cutis laxa, type 1 \| Autosomal recessive cutis laxa with severe systemic involvement \| Autosomal recessive cutis laxa, pulmonary emphysema type [NA07.Z] Intracranial injury, unspecified Also known as: Intracranial injury, unspecified \| Intracranial injury \| Closed head injury \| brain injury NOS \| cerebral injury === GRAPH WALKS === --- Walk 1 --- [FC0Z] Diseases of the musculoskeletal system or connective tissue, unspecified --PARENT--> [15] Diseases of the musculoskeletal system or connective tissue Def: This chapter contains diseases of musculoskeletal system and diseases of connective tissue.... --CHILD--> [?] Conditions associated with the spine Def: This is a group of conditions in which there is a deviation from or interruption of the normal structure or function of the spine.... --- Walk 2 --- [FC0Z] Diseases of the musculoskeletal system or connective tissue, unspecified --PARENT--> [15] Diseases of the musculoskeletal system or connective tissue Def: This chapter contains diseases of musculoskeletal system and diseases of connective tissue.... --RELATED_TO--> [?] Nonorgan specific systemic autoimmune disorders --- Walk 3 --- [FB84.Z] Osteomyelitis or osteitis, unspecified --PARENT--> [FB84] Osteomyelitis or osteitis --EXCLUDES--> [?] Inflammatory conditions of jaws --- Walk 4 --- [FB84.Z] Osteomyelitis or osteitis, unspecified --PARENT--> [FB84] Osteomyelitis or osteitis --EXCLUDES--> [?] Infection of vertebra Def: A condition of the vertebrae, caused by an infection with a bacterial, viral, fungal, or parasitic source. This condition commonly presents with fever, chills, headache, weight loss, or may be asympto... --- Walk 5 --- [FB80.Z] Disorder of bone density or structure, unspecified --PARENT--> [FB80] Certain specified disorders of bone density or structure --RELATED_TO--> [?] Osteogenesis imperfecta Def: Osteogenesis imperfecta (OI) comprises a heterogeneous group of genetic disorders characterised by increased bone fragility, low bone mass, and susceptibility to bone fractures with variable severity.... --- Walk 6 --- [FB80.Z] Disorder of bone density or structure, unspecified --PARENT--> [FB80] Certain specified disorders of bone density or structure --RELATED_TO--> [?] Osteogenesis imperfecta Def: Osteogenesis imperfecta (OI) comprises a heterogeneous group of genetic disorders characterised by increased bone fragility, low bone mass, and susceptibility to bone fractures with variable severity....	[ "[FC0Z] Diseases of the musculoskeletal system or connective tissue, unspecified\n --PARENT--> [15] Diseases of the musculoskeletal system or connective tissue\n Def: This chapter contains diseases of musculoskeletal system and diseases of connective tissue....\n --CHILD--> [?] Conditions associated with the spine\n Def: This is a group of conditions in which there is a deviation from or interruption of the normal structure or function of the spine....", "[FC0Z] Diseases of the musculoskeletal system or connective tissue, unspecified\n --PARENT--> [15] Diseases of the musculoskeletal system or connective tissue\n Def: This chapter contains diseases of musculoskeletal system and diseases of connective tissue....\n --RELATED_TO--> [?] Nonorgan specific systemic autoimmune disorders", "[FB84.Z] Osteomyelitis or osteitis, unspecified\n --PARENT--> [FB84] Osteomyelitis or osteitis\n --EXCLUDES--> [?] Inflammatory conditions of jaws", "[FB84.Z] Osteomyelitis or osteitis, unspecified\n --PARENT--> [FB84] Osteomyelitis or osteitis\n --EXCLUDES--> [?] Infection of vertebra\n Def: A condition of the vertebrae, caused by an infection with a bacterial, viral, fungal, or parasitic source. This condition commonly presents with fever, chills, headache, weight loss, or may be asympto...", "[FB80.Z] Disorder of bone density or structure, unspecified\n --PARENT--> [FB80] Certain specified disorders of bone density or structure\n --RELATED_TO--> [?] Osteogenesis imperfecta\n Def: Osteogenesis imperfecta (OI) comprises a heterogeneous group of genetic disorders characterised by increased bone fragility, low bone mass, and susceptibility to bone fractures with variable severity....", "[FB80.Z] Disorder of bone density or structure, unspecified\n --PARENT--> [FB80] Certain specified disorders of bone density or structure\n --RELATED_TO--> [?] Osteogenesis imperfecta\n Def: Osteogenesis imperfecta (OI) comprises a heterogeneous group of genetic disorders characterised by increased bone fragility, low bone mass, and susceptibility to bone fractures with variable severity...." ]	FC0Z	Diseases of the musculoskeletal system or connective tissue, unspecified	[ { "from_icd11": "FC0Z", "icd10_code": "XIII", "icd10_title": "" }, { "from_icd11": "FB84.Z", "icd10_code": "M86672", "icd10_title": "Other chronic osteomyelitis, left ankle and foot" }, { "from_icd11": "FB84.Z", "icd10_code": "M86172", "icd10_title": "Other acute osteomyelitis, left ankle and foot" }, { "from_icd11": "FB84.Z", "icd10_code": "M86171", "icd10_title": "Other acute osteomyelitis, right ankle and foot" }, { "from_icd11": "FB84.Z", "icd10_code": "M86671", "icd10_title": "Other chronic osteomyelitis, right ankle and foot" }, { "from_icd11": "FB84.Z", "icd10_code": "M868X7", "icd10_title": "Other osteomyelitis, ankle and foot" }, { "from_icd11": "FB84.Z", "icd10_code": "M868X8", "icd10_title": "Other osteomyelitis, other site" }, { "from_icd11": "FB84.Z", "icd10_code": "M868X6", "icd10_title": "Other osteomyelitis, lower leg" }, { "from_icd11": "FB84.Z", "icd10_code": "M868X9", "icd10_title": "Other osteomyelitis, unspecified sites" }, { "from_icd11": "FB84.Z", "icd10_code": "M8668", "icd10_title": "Other chronic osteomyelitis, other site" }, { "from_icd11": "FB84.Z", "icd10_code": "M86662", "icd10_title": "Other chronic osteomyelitis, left tibia and fibula" }, { "from_icd11": "FB84.Z", "icd10_code": "M86151", "icd10_title": "Other acute osteomyelitis, right femur" }, { "from_icd11": "FB84.Z", "icd10_code": "M86141", "icd10_title": "Other acute osteomyelitis, right hand" }, { "from_icd11": "FB84.Z", "icd10_code": "M86641", "icd10_title": "Other chronic osteomyelitis, right hand" }, { "from_icd11": "FB84.Z", "icd10_code": "M8669", "icd10_title": "Other chronic osteomyelitis, multiple sites" } ]	XIII
To pick up an object we using the hand, this function provided particularly by thumb-index pinch . This operation of the clip is provided by the digital and the muscle with the tendon bone chain termination. Moreover, the extensor apparatus of the finger is a complex structure and injury can lead to significant digital dysfunction. Besides, closed central slip injuries could be missed and diagnosis might be delayed because of the lack of an open wound and often with no radiographic abnormality; this could results boutonniere deformities if they were untreated . Many procedures were described in literature with no recommendation of a standard treatment (whether Conservative treatment or surgical) . Dorsal dislocations of the interphalangeal joint are common injuries and reduction is usually obtained by manipulation. When it is irreducible then we have to think of an interposition between the joint surfaces. In this report we aim to present the case of a patient with laceration of the central slip of the extensor tendon at the proximal interphalangeal (PIP) joint with volar displacement of the lateral bands which could results the so-called boutonniere deformity that includes a loss of extension at the PIP joint and compensatory hyperextension of the distal interphalangeal (DIP) joint associated to a dislocated interphalangeal thumb of the same hand with less power in the clip thumb and index finger.	4.046875	0.945313	sec[0]/p[0]	en	0.999997	25426188	https://doi.org/10.11604/pamj.2014.18.230.3240	[ "joint", "this", "interphalangeal", "thumb", "hand", "provided", "index", "clip", "digital", "tendon" ]	[ { "code": "FA5Z", "title": "Arthropathies, unspecified" }, { "code": "FA2Z", "title": "Inflammatory arthropathies, unspecified" }, { "code": "FA36.Z", "title": "Effusion of joint, unspecified" }, { "code": "FA37.Y", "title": "Other specified certain joint disorders, not elsewhere classified" }, { "code": "FA34.3", "title": "Contracture of joint" }, { "code": "4A01.03", "title": "Transient hypogammaglobulinaemia of infancy" }, { "code": "ND14.8Z&XA04T7", "title": "Sprain of interphalangeal joint of toe" }, { "code": "NC54.81", "title": "Strain or sprain of interphalangeal joint of finger" }, { "code": "NC54.71", "title": "Strain or sprain of interphalangeal joint of thumb" }, { "code": "NC54.21", "title": "Dislocation of interphalangeal joint of finger" } ]	=== ICD-11 CODES FOUND === [FA5Z] Arthropathies, unspecified Also known as: Arthropathies, unspecified \| Disorders affecting predominantly peripheral joints \| Disorders affecting predominantly peripheral limb joints \| arthropathy NOS \| arthropathic [FA2Z] Inflammatory arthropathies, unspecified Also known as: Inflammatory arthropathies, unspecified \| polyarthritis NOS \| inflammatory joint disease NOS \| nonpyogenic arthritis NOS \| arthritic nodosa [FA36.Z] Effusion of joint, unspecified Also known as: Effusion of joint, unspecified \| Effusion of joint \| effusion into joint \| effusion of joint, site unspecified \| hydrarthrosis [FA37.Y] Other specified certain joint disorders, not elsewhere classified Also known as: Other specified certain joint disorders, not elsewhere classified \| Calcification of joint \| Periarticular calcification \| Periarticular ossification \| Fistula of joint [FA34.3] Contracture of joint Also known as: Contracture of joint \| contracture of joint, site unspecified \| joint contraction \| joint contracture \| abduction contracture joint Excludes: Dupuytren contracture \| contracture of tendon (sheath) without contracture of joint \| acquired deformities of limbs [4A01.03] Transient hypogammaglobulinaemia of infancy Also known as: Transient hypogammaglobulinaemia of infancy \| immunoglobulin maturational delay \| THI - [transient hypogammaglobulinaemia of infancy] [NC54.81] Strain or sprain of interphalangeal joint of finger Also known as: Strain or sprain of interphalangeal joint of finger [NC54.71] Strain or sprain of interphalangeal joint of thumb Also known as: Strain or sprain of interphalangeal joint of thumb [NC54.21] Dislocation of interphalangeal joint of finger Also known as: Dislocation of interphalangeal joint of finger === GRAPH WALKS === --- Walk 1 --- [FA5Z] Arthropathies, unspecified --PARENT--> [?] Arthropathies --CHILD--> [?] Infection related arthropathies Def: A disease of the joints, caused by an infection with a bacterial, viral, fungal, or parasitic source. Distinction is made between the following types of etiological relationship. a) direct infection ... --- Walk 2 --- [FA5Z] Arthropathies, unspecified --PARENT--> [?] Arthropathies --CHILD--> [?] Inflammatory arthropathies --- Walk 3 --- [FA2Z] Inflammatory arthropathies, unspecified --PARENT--> [?] Inflammatory arthropathies --CHILD--> [FA22] Polymyalgia rheumatica Def: Polymyalgia rheumatica (PMR) is a syndrome characterised by aching of the proximal portions of the extremities and torso. Provisional classification criteria for PMR by the European League Against Rhe... --- Walk 4 --- [FA2Z] Inflammatory arthropathies, unspecified --PARENT--> [?] Inflammatory arthropathies --RELATED_TO--> [?] Peripheral spondyloarthritis Def: Experts from the Assessment of SpondyloArthritis international Society (ASAS) developed classification criteria for axSpA and peripheral SpA. These criteria were developed for patients with peripheral... --- Walk 5 --- [FA36.Z] Effusion of joint, unspecified --PARENT--> [FA36] Effusion of joint Def: Increased intra-articular fluid secondary to trauma and/or other acquired conditions not detailed in other codes.... --CHILD--> [FA36.0] Effusion of joint containing blood --- Walk 6 --- [FA36.Z] Effusion of joint, unspecified --PARENT--> [FA36] Effusion of joint Def: Increased intra-articular fluid secondary to trauma and/or other acquired conditions not detailed in other codes.... --CHILD--> [FA36.Z] Effusion of joint, unspecified	[ "[FA5Z] Arthropathies, unspecified\n --PARENT--> [?] Arthropathies\n --CHILD--> [?] Infection related arthropathies\n Def: A disease of the joints, caused by an infection with a bacterial, viral, fungal, or parasitic source.\n\nDistinction is made between the following types of etiological relationship.\na) direct infection ...", "[FA5Z] Arthropathies, unspecified\n --PARENT--> [?] Arthropathies\n --CHILD--> [?] Inflammatory arthropathies", "[FA2Z] Inflammatory arthropathies, unspecified\n --PARENT--> [?] Inflammatory arthropathies\n --CHILD--> [FA22] Polymyalgia rheumatica\n Def: Polymyalgia rheumatica (PMR) is a syndrome characterised by aching of the proximal portions of the extremities and torso. Provisional classification criteria for PMR by the European League Against Rhe...", "[FA2Z] Inflammatory arthropathies, unspecified\n --PARENT--> [?] Inflammatory arthropathies\n --RELATED_TO--> [?] Peripheral spondyloarthritis\n Def: Experts from the Assessment of SpondyloArthritis international Society (ASAS) developed classification criteria for axSpA and peripheral SpA. These criteria were developed for patients with peripheral...", "[FA36.Z] Effusion of joint, unspecified\n --PARENT--> [FA36] Effusion of joint\n Def: Increased intra-articular fluid secondary to trauma and/or other acquired conditions not detailed in other codes....\n --CHILD--> [FA36.0] Effusion of joint containing blood", "[FA36.Z] Effusion of joint, unspecified\n --PARENT--> [FA36] Effusion of joint\n Def: Increased intra-articular fluid secondary to trauma and/or other acquired conditions not detailed in other codes....\n --CHILD--> [FA36.Z] Effusion of joint, unspecified" ]	FA5Z	Arthropathies, unspecified	[ { "from_icd11": "FA5Z", "icd10_code": "M00-M25", "icd10_title": "" }, { "from_icd11": "FA2Z", "icd10_code": "M1389", "icd10_title": "Other specified arthritis, multiple sites" }, { "from_icd11": "FA2Z", "icd10_code": "M1380", "icd10_title": "Other specified arthritis, unspecified site" }, { "from_icd11": "FA2Z", "icd10_code": "M13862", "icd10_title": "Other specified arthritis, left knee" }, { "from_icd11": "FA2Z", "icd10_code": "M13872", "icd10_title": "Other specified arthritis, left ankle and foot" }, { "from_icd11": "FA2Z", "icd10_code": "M13871", "icd10_title": "Other specified arthritis, right ankle and foot" }, { "from_icd11": "FA2Z", "icd10_code": "M13861", "icd10_title": "Other specified arthritis, right knee" }, { "from_icd11": "FA2Z", "icd10_code": "M13879", "icd10_title": "Other specified arthritis, unspecified ankle and foot" }, { "from_icd11": "FA2Z", "icd10_code": "M13842", "icd10_title": "Other specified arthritis, left hand" }, { "from_icd11": "FA2Z", "icd10_code": "M13841", "icd10_title": "Other specified arthritis, right hand" }, { "from_icd11": "FA2Z", "icd10_code": "M13811", "icd10_title": "Other specified arthritis, right shoulder" }, { "from_icd11": "FA2Z", "icd10_code": "M13162", "icd10_title": "Monoarthritis, not elsewhere classified, left knee" }, { "from_icd11": "FA2Z", "icd10_code": "M13869", "icd10_title": "Other specified arthritis, unspecified knee" }, { "from_icd11": "FA2Z", "icd10_code": "M1388", "icd10_title": "Other specified arthritis, other site" }, { "from_icd11": "FA2Z", "icd10_code": "M13171", "icd10_title": "Monoarthritis, not elsewhere classified, right ankle and foot" } ]	M00-M25
Patient 8 was a 67‐year‐old woman with cardiac metastasis of thymic origin. She initially received 20 Gy in 5 fractions, and 39 Gy in 13 fractions 6 months later to achieve better response in the mediastinum. The tumor showed radiological response to RT, and she had stable disease for about 1 year until CT imaging showed a mural‐based cardiac metastasis with significant involvement of the right atrium and superior vena cava (SVC). She was mildly symptomatic from this mass. After discussion in multidisciplinary tumor board, she received RT targeted to the metastatic tumor area to avoid the development of SVC obstruction (SVCO) given that surgical resection was not feasible and she had excellent response to RT in the irradiated area. Because of overlap with the previous radiation field and in order to minimize any risk to the normal structures, RT was given as 30 Gy in 20 fractions twice a day. She tolerated treatment well with minimal side effects. A follow‐up CT scan 1 month after RT revealed an interval reduction in the size of tumor in the right atrium. She remained well with no clinical or radiologic evidence of cardiac tumor progression till 6 months after RT, when CT imaging showed an increase in the size of residual tumor and she became symptomatic with symptoms of SVCO. Her disease was not amenable to any treatment, and she went on SVC stent placement followed by referral to palliative care.	3.892578	0.979492	sec[1]/sec[4]/p[0]	en	0.999994	26880683	https://doi.org/10.1002/cam4.619	[ "tumor", "cardiac", "fractions", "response", "metastasis", "imaging", "atrium", "symptomatic", "area", "svco" ]	[ { "code": "2F9Z", "title": "Neoplasms of unknown behaviour of unspecified site" }, { "code": "ME61", "title": "Subcutaneous swelling, mass or lump of uncertain or unspecified nature" }, { "code": "2E6Z", "title": "Carcinoma in situ of unspecified site" }, { "code": "2F91.1", "title": "Neoplasms of unknown behaviour of trachea, bronchus or lung" }, { "code": "2F92", "title": "Neoplasms of unknown behaviour of skin" }, { "code": "BE2Y", "title": "Other specified diseases of the circulatory system" }, { "code": "BC4Z", "title": "Diseases of the myocardium or cardiac chambers, unspecified" }, { "code": "BD1Z", "title": "Heart failure, unspecified" }, { "code": "LA8Z", "title": "Structural developmental anomaly of heart or great vessels, unspecified" }, { "code": "BA41.Z", "title": "Acute myocardial infarction, unspecified" } ]	=== ICD-11 CODES FOUND === [2F9Z] Neoplasms of unknown behaviour of unspecified site Also known as: Neoplasms of unknown behaviour of unspecified site \| neoplasia \| neoplasm growth NOS \| tumour of unspecified site \| tumourlet of unspecified site [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Definition: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature Also known as: Subcutaneous swelling, mass or lump of uncertain or unspecified nature \| localised swelling, mass or lump of skin and subcutaneous tissue \| localised subcutaneous nodules \| subcutaneous nodules \| superficial subcutaneous nodules Excludes: localized adiposity \| mass and lump: breast \| enlarged lymph nodes [2E6Z] Carcinoma in situ of unspecified site Also known as: Carcinoma in situ of unspecified site \| carcinoma in situ of unspecified site \| carcinoma in situ NOS \| carcinoma in situ \| in situ neoplasm [2F91.1] Neoplasms of unknown behaviour of trachea, bronchus or lung Also known as: Neoplasms of unknown behaviour of trachea, bronchus or lung \| trachea, bronchus or lung tumour NOS \| Intravascular bronchial alveolar tumour of unspecified site \| Bronchial adenoma of unknown behaviour of unspecified site \| Intravascular bronchial alveolar tumour unknown behaviour of unspecified site [2F92] Neoplasms of unknown behaviour of skin Also known as: Neoplasms of unknown behaviour of skin \| skin tumour NOS [BE2Y] Other specified diseases of the circulatory system Also known as: Other specified diseases of the circulatory system \| Certain specified forms of heart disease \| Cardiac disorder, unspecified \| disorder of heart NOS \| organic disease or disorder of heart [BC4Z] Diseases of the myocardium or cardiac chambers, unspecified Also known as: Diseases of the myocardium or cardiac chambers, unspecified \| Heart disease NOS \| cardiac disease NOS [BD1Z] Heart failure, unspecified Also known as: Heart failure, unspecified \| myocardial failure \| cardiac decompensation \| cardiac failure \| cardiac failure NOS [LA8Z] Structural developmental anomaly of heart or great vessels, unspecified Also known as: Structural developmental anomaly of heart or great vessels, unspecified \| Heart malformations \| Cardiac malformations \| congenital anomaly of heart \| congenital heart disease [BA41.Z] Acute myocardial infarction, unspecified Also known as: Acute myocardial infarction, unspecified \| Acute myocardial infarction \| cardiac attack \| heart attack \| acute cardiac infarction === GRAPH WALKS === --- Walk 1 --- [2F9Z] Neoplasms of unknown behaviour of unspecified site --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues --RELATED_TO--> [?] Pathological fracture in neoplastic disease of unknown behaviour --- Walk 2 --- [2F9Z] Neoplasms of unknown behaviour of unspecified site --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues --CHILD--> [2F90] Neoplasms of unknown behaviour of oral cavity or digestive organs --- Walk 3 --- [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature... --EXCLUDES--> [?] Enlarged lymph nodes Def: Enlarged lymph node is called lymphadenopathy which means the abnormal enlargement of lymph nodes.... --CHILD--> [?] Generalised lymph node enlargement --- Walk 4 --- [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature... --EXCLUDES--> [?] Enlarged lymph nodes Def: Enlarged lymph node is called lymphadenopathy which means the abnormal enlargement of lymph nodes.... --EXCLUDES--> [?] Nonspecific mesenteric lymphadenitis --- Walk 5 --- [2E6Z] Carcinoma in situ of unspecified site --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues --CHILD--> [2E60] Carcinoma in situ of oral cavity, oesophagus or stomach --- Walk 6 --- [2E6Z] Carcinoma in situ of unspecified site --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues --PARENT--> [02] Neoplasms Def: An abnormal or uncontrolled cellular proliferation which is not coordinated with an organism's requirements for normal tissue growth, replacement or repair....	[ "[2F9Z] Neoplasms of unknown behaviour of unspecified site\n --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues\n --RELATED_TO--> [?] Pathological fracture in neoplastic disease of unknown behaviour", "[2F9Z] Neoplasms of unknown behaviour of unspecified site\n --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues\n --CHILD--> [2F90] Neoplasms of unknown behaviour of oral cavity or digestive organs", "[ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature\n Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature...\n --EXCLUDES--> [?] Enlarged lymph nodes\n Def: Enlarged lymph node is called lymphadenopathy which means the abnormal enlargement of lymph nodes....\n --CHILD--> [?] Generalised lymph node enlargement", "[ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature\n Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature...\n --EXCLUDES--> [?] Enlarged lymph nodes\n Def: Enlarged lymph node is called lymphadenopathy which means the abnormal enlargement of lymph nodes....\n --EXCLUDES--> [?] Nonspecific mesenteric lymphadenitis", "[2E6Z] Carcinoma in situ of unspecified site\n --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues\n --CHILD--> [2E60] Carcinoma in situ of oral cavity, oesophagus or stomach", "[2E6Z] Carcinoma in situ of unspecified site\n --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues\n --PARENT--> [02] Neoplasms\n Def: An abnormal or uncontrolled cellular proliferation which is not coordinated with an organism's requirements for normal tissue growth, replacement or repair...." ]	2F9Z	Neoplasms of unknown behaviour of unspecified site	[ { "from_icd11": "2F9Z", "icd10_code": "D487", "icd10_title": "Neoplasm of uncertain behavior of other specified sites" }, { "from_icd11": "2F9Z", "icd10_code": "D482", "icd10_title": "Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system" }, { "from_icd11": "2F9Z", "icd10_code": "D37-D48", "icd10_title": "" }, { "from_icd11": "2F9Z", "icd10_code": "D377", "icd10_title": "" }, { "from_icd11": "2F9Z", "icd10_code": "D48", "icd10_title": "Neoplasm of uncertain behavior of other and unspecified sites" }, { "from_icd11": "2F9Z", "icd10_code": "D489", "icd10_title": "Neoplasm of uncertain behavior, unspecified" }, { "from_icd11": "ME61", "icd10_code": "R2240", "icd10_title": "Localized swelling, mass and lump, unspecified lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2232", "icd10_title": "Localized swelling, mass and lump, left upper limb" }, { "from_icd11": "ME61", "icd10_code": "R2242", "icd10_title": "Localized swelling, mass and lump, left lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2231", "icd10_title": "Localized swelling, mass and lump, right upper limb" }, { "from_icd11": "ME61", "icd10_code": "R2241", "icd10_title": "Localized swelling, mass and lump, right lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2233", "icd10_title": "Localized swelling, mass and lump, upper limb, bilateral" }, { "from_icd11": "ME61", "icd10_code": "R2243", "icd10_title": "Localized swelling, mass and lump, lower limb, bilateral" }, { "from_icd11": "ME61", "icd10_code": "R2230", "icd10_title": "Localized swelling, mass and lump, unspecified upper limb" }, { "from_icd11": "ME61", "icd10_code": "R220", "icd10_title": "Localized swelling, mass and lump, head" } ]	D487	Neoplasm of uncertain behavior of other specified sites
To stop the fibro-inflammatory reaction from progressing further, the acute phase reaction, and its systemic manifestations, inhibit or improve the compression of the ureters or other retroperitoneal structures, for which corticosteroids are the mainstay of therapy. Tamoxifen or immunosuppressants such as azathioprine and cyclophosphamide is a preferable alternative when steroids are contraindicated, but with a higher relapse rate compared to steroids, thus used as second-line drugs in patients who are refractory to steroids. Biological agents, such as rituximab, tocilizumab, and infliximab, have been tried in refractory IRPF cases, but less data is available to date . Surgery is generally done to relieve obstruction of the ureters; Open ureterolysis with intraperitoneal transposition and omental envelope of the ureters is opined as the best approach for surgical intervention. Surgical interventions do not help in preventing the progression of the disease or in its recurrence. Surgery must be given with systemic steroid therapy. The conservative management comprises systemic treatment with stent placement in ureters or nephrostomies has been suggested, therefore reserving surgical management in refractory cases . Our patient was treated with a low-dose systemic steroid along with treatment for AKI, and bilateral ureteric stent placement was done by the urologist to relieve the ureteric obstruction.	4.160156	0.806152	sec[2]/p[3]	en	0.999997	36320943	https://doi.org/10.7759/cureus.29582	[ "systemic", "ureters", "steroids", "refractory", "reaction", "cases", "relieve", "obstruction", "steroid", "stent" ]	[ { "code": "4A42.Z", "title": "Systemic sclerosis, unspecified" }, { "code": "4A4Z", "title": "Nonorgan specific systemic autoimmune disorders, unspecified" }, { "code": "CB7Z", "title": "Diseases of the respiratory system, unspecified" }, { "code": "4B4Z", "title": "Diseases of the immune system, unspecified" }, { "code": "GC2Z", "title": "Diseases of the urinary system, unspecified" }, { "code": "6C4H.Y", "title": "Other specified disorders due to use of non-psychoactive substances" }, { "code": "MA12.4", "title": "Finding of steroid agent in blood" }, { "code": "6C4H.1Z", "title": "Harmful pattern of use of non-psychoactive substances, unspecified" }, { "code": "MF99", "title": "Elevated urine levels of drugs, medicaments and biological substances" }, { "code": "2F32.Y", "title": "Other specified benign neoplasm of ovary" } ]	=== ICD-11 CODES FOUND === [4A42.Z] Systemic sclerosis, unspecified Also known as: Systemic sclerosis, unspecified \| Systemic sclerosis \| Systemic scleroderma \| progressive scleroderma \| Acroscleriasis [4A4Z] Nonorgan specific systemic autoimmune disorders, unspecified Also known as: Nonorgan specific systemic autoimmune disorders, unspecified \| systemic autoimmune disease \| systemic collagen vascular disease \| systemic vascular disease \| autoimmune disease NOS [CB7Z] Diseases of the respiratory system, unspecified Also known as: Diseases of the respiratory system, unspecified \| disorder of respiratory system \| respiratory disease NOS \| respiratory tract disease \| respiratory disorder NOS [4B4Z] Diseases of the immune system, unspecified Also known as: Diseases of the immune system, unspecified \| immunological defect NOS \| immunity disorder NOS \| immune mechanism disorder NOS \| immune compromised NOS [GC2Z] Diseases of the urinary system, unspecified Also known as: Diseases of the urinary system, unspecified \| urinary tract disease NOS \| Abnormal renal function \| kidney dysfunction NOS \| kidney hypofunction [6C4H.Y] Other specified disorders due to use of non-psychoactive substances Also known as: Other specified disorders due to use of non-psychoactive substances \| Steroid dependence [MA12.4] Finding of steroid agent in blood Also known as: Finding of steroid agent in blood \| steroid in blood [6C4H.1Z] Harmful pattern of use of non-psychoactive substances, unspecified Also known as: Harmful pattern of use of non-psychoactive substances, unspecified \| Harmful pattern of use of non-psychoactive substances \| harmful use of nonprescribed drugs, non-dependence producing \| Abuse of antacids \| Abuse of herbal or folk remedies [MF99] Elevated urine levels of drugs, medicaments and biological substances Definition: Elevated urine levels of drugs, medicaments and biological substances mean that the levels of drugs, medicaments, and biological substances have elevated on the urine examination. Also known as: Elevated urine levels of drugs, medicaments and biological substances \| Elevated urine levels of 17-ketosteroids \| Elevated urine levels of catecholamines \| Elevated urine levels of indoleacetic acid \| Elevated urine levels of steroids [2F32.Y] Other specified benign neoplasm of ovary Also known as: Other specified benign neoplasm of ovary \| Serous or mucinous ovarian cystadenoma of childhood \| Benign androblastoma of ovary \| tubular androblastoma of unspecified site, female \| Adenofibroma of ovary === GRAPH WALKS === --- Walk 1 --- [4A42.Z] Systemic sclerosis, unspecified --PARENT--> [4A42] Systemic sclerosis Def: Systemic sclerosis is a systemic disorder of the connective tissue; manifested by hardening and thickening of the skin, by abnormalities involving the microvasculature and larger vessels, and by fibro... --CHILD--> [4A42.0] Paediatric onset systemic sclerosis Def: Systemic sclerosis arising before the age of 16. Involvement of internal organs is less common but arthritis and myositis are more common than in adults.... --- Walk 2 --- [4A42.Z] Systemic sclerosis, unspecified --PARENT--> [4A42] Systemic sclerosis Def: Systemic sclerosis is a systemic disorder of the connective tissue; manifested by hardening and thickening of the skin, by abnormalities involving the microvasculature and larger vessels, and by fibro... --CHILD--> [4A42.2] Limited systemic sclerosis Def: Combination of calcinosis, Raynaud phenomenon, oesophageal dysfunction, sclerodactyly and telangiectasia.... --- Walk 3 --- [4A4Z] Nonorgan specific systemic autoimmune disorders, unspecified --PARENT--> [?] Nonorgan specific systemic autoimmune disorders --CHILD--> [4A41] Idiopathic inflammatory myopathy Def: These comprise a diverse group of syndromes that have in common persistent muscle inflammation of unknown pathophysiology, resulting in damage that affects muscle function. The inflammatory muscle dis... --- Walk 4 --- [4A4Z] Nonorgan specific systemic autoimmune disorders, unspecified --PARENT--> [?] Nonorgan specific systemic autoimmune disorders --CHILD--> [4A42] Systemic sclerosis Def: Systemic sclerosis is a systemic disorder of the connective tissue; manifested by hardening and thickening of the skin, by abnormalities involving the microvasculature and larger vessels, and by fibro... --- Walk 5 --- [CB7Z] Diseases of the respiratory system, unspecified --PARENT--> [12] Diseases of the respiratory system --EXCLUDES--> [?] Developmental anomalies Def: This chapter includes conditions caused by failure of a particular body site or body system to develop correctly during the antenatal period.... --- Walk 6 --- [CB7Z] Diseases of the respiratory system, unspecified --PARENT--> [12] Diseases of the respiratory system --CHILD--> [?] Upper respiratory tract disorders Def: This group of disorders refers to diseases of the upper airways (upper respiratory tract). The upper airways anatomically are complicated structures which extend from the airway openings at the nares ...	[ "[4A42.Z] Systemic sclerosis, unspecified\n --PARENT--> [4A42] Systemic sclerosis\n Def: Systemic sclerosis is a systemic disorder of the connective tissue; manifested by hardening and thickening of the skin, by abnormalities involving the microvasculature and larger vessels, and by fibro...\n --CHILD--> [4A42.0] Paediatric onset systemic sclerosis\n Def: Systemic sclerosis arising before the age of 16. Involvement of internal organs is less common but arthritis and myositis are more common than in adults....", "[4A42.Z] Systemic sclerosis, unspecified\n --PARENT--> [4A42] Systemic sclerosis\n Def: Systemic sclerosis is a systemic disorder of the connective tissue; manifested by hardening and thickening of the skin, by abnormalities involving the microvasculature and larger vessels, and by fibro...\n --CHILD--> [4A42.2] Limited systemic sclerosis\n Def: Combination of calcinosis, Raynaud phenomenon, oesophageal dysfunction, sclerodactyly and telangiectasia....", "[4A4Z] Nonorgan specific systemic autoimmune disorders, unspecified\n --PARENT--> [?] Nonorgan specific systemic autoimmune disorders\n --CHILD--> [4A41] Idiopathic inflammatory myopathy\n Def: These comprise a diverse group of syndromes that have in common persistent muscle inflammation of unknown pathophysiology, resulting in damage that affects muscle function. The inflammatory muscle dis...", "[4A4Z] Nonorgan specific systemic autoimmune disorders, unspecified\n --PARENT--> [?] Nonorgan specific systemic autoimmune disorders\n --CHILD--> [4A42] Systemic sclerosis\n Def: Systemic sclerosis is a systemic disorder of the connective tissue; manifested by hardening and thickening of the skin, by abnormalities involving the microvasculature and larger vessels, and by fibro...", "[CB7Z] Diseases of the respiratory system, unspecified\n --PARENT--> [12] Diseases of the respiratory system\n --EXCLUDES--> [?] Developmental anomalies\n Def: This chapter includes conditions caused by failure of a particular body site or body system to develop correctly during the antenatal period....", "[CB7Z] Diseases of the respiratory system, unspecified\n --PARENT--> [12] Diseases of the respiratory system\n --CHILD--> [?] Upper respiratory tract disorders\n Def: This group of disorders refers to diseases of the upper airways (upper respiratory tract). The upper airways anatomically are complicated structures which extend from the airway openings at the nares ..." ]	4A42.Z	Systemic sclerosis, unspecified	[ { "from_icd11": "4A42.Z", "icd10_code": "M3481", "icd10_title": "Systemic sclerosis with lung involvement" }, { "from_icd11": "4A42.Z", "icd10_code": "M3489", "icd10_title": "Other systemic sclerosis" }, { "from_icd11": "4A42.Z", "icd10_code": "M3483", "icd10_title": "Systemic sclerosis with polyneuropathy" }, { "from_icd11": "4A42.Z", "icd10_code": "M349", "icd10_title": "Systemic sclerosis, unspecified" }, { "from_icd11": "4A42.Z", "icd10_code": "M342", "icd10_title": "Systemic sclerosis induced by drug and chemical" }, { "from_icd11": "4A42.Z", "icd10_code": "M34", "icd10_title": "Systemic sclerosis [scleroderma]" }, { "from_icd11": "4A42.Z", "icd10_code": "M348", "icd10_title": "Other forms of systemic sclerosis" }, { "from_icd11": "4A4Z", "icd10_code": "M358", "icd10_title": "Other specified systemic involvement of connective tissue" }, { "from_icd11": "4A4Z", "icd10_code": "M359", "icd10_title": "Systemic involvement of connective tissue, unspecified" }, { "from_icd11": "4A4Z", "icd10_code": "M368", "icd10_title": "Systemic disorders of connective tissue in other diseases classified elsewhere" }, { "from_icd11": "4A4Z", "icd10_code": "M30-M36", "icd10_title": "" }, { "from_icd11": "4A4Z", "icd10_code": "M35", "icd10_title": "Other systemic involvement of connective tissue" }, { "from_icd11": "4A4Z", "icd10_code": "M36", "icd10_title": "Systemic disorders of connective tissue in diseases classified elsewhere" }, { "from_icd11": "CB7Z", "icd10_code": "J989", "icd10_title": "Respiratory disorder, unspecified" }, { "from_icd11": "CB7Z", "icd10_code": "X", "icd10_title": "" } ]	M3481	Systemic sclerosis with lung involvement
Vibrio species are a group of water bacteria that are often found in brackish or marine habitats. Vibrio cholerae , Vibrio vulnificus , and Vibrio parahaemolyticus are the three Vibrio species that are currently recognized to be responsible for the majority of human illnesses. Vibrio mimicus and Vibrio cholerae are genetically and phenotypically distinct from one another; however, V. cholerae can cause diarrheal disease because it secretes choleric toxin. Seafood, marine samples, human diarrheal stools, acute otitis brought on by exposure to seawater, and eggs in nests have all been linked to Vibrio mimicus . There have not yet been any cases of bacterial meningitis caused by V. mimicus reported in the most recent medical literature. At any age, Vibrio species are not known to cause meningitis. If this occurs, these pathogens are thought to infiltrate the central nervous system through an immune-compromised state and bloodstream infection . Additionally, further research on the neurological manifestations of Vibrio mimicus is necessary. Here, we present a rare instance of a young person treated successfully with intravenous antibiotics, steroids, antimalarials, and other supportive drugs for bacterial meningoencephalitis brought on by Vibrio mimicus , falciparum malaria, and leptospirosis. A healthy male has been reported as the first potential case of meningoencephalitis caused by Vibrio mimicus .	4.199219	0.84082	sec[0]/p[3]	en	0.999996	PMC10511350	https://doi.org/10.7759/cureus.43879	[ "vibrio", "mimicus", "species", "cholerae", "that", "marine", "human", "cause", "diarrheal", "brought" ]	[ { "code": "1A01", "title": "Intestinal infection due to other Vibrio" }, { "code": "MG50.BZ", "title": "Vibrio resistant to unspecified antibiotic" }, { "code": "1A01&XN1AA", "title": "Infections due to Vibrio parahaemolyticus" }, { "code": "1A01&XN44G", "title": "Infections due to Vibrio vulnificus" }, { "code": "MG50.BY", "title": "Vibrio resistant to other antibiotic" }, { "code": "1F85", "title": "Paragonimiasis" }, { "code": "1F6F", "title": "Trichostrongyliasis" }, { "code": "1F86.Z", "title": "Schistosomiasis due to unspecified or unknown Schistosoma species" }, { "code": "1C1B.Y", "title": "Other specified forms of nocardiosis" }, { "code": "1B91", "title": "Leptospirosis" } ]	=== ICD-11 CODES FOUND === [1A01] Intestinal infection due to other Vibrio Also known as: Intestinal infection due to other Vibrio \| Infections due to Vibrio parahaemolyticus \| Infections due to Vibrio vulnificus [MG50.BZ] Vibrio resistant to unspecified antibiotic Also known as: Vibrio resistant to unspecified antibiotic \| Antibiotic resistant Vibrio [MG50.BY] Vibrio resistant to other antibiotic Also known as: Vibrio resistant to other antibiotic [1F85] Paragonimiasis Definition: A disease caused by an infection with the parasitic worm Paragonimus. This disease is characterised by cough or haemoptysis, or may be asymptomatic. This disease may present with other symptoms depending on the site where the parasite migrates to. Transmission is commonly by ingestion of undercooked contaminated crustaceans (crab or crayfish). Confirmation is commonly by identification of Paragonimus eggs in a sputum or faecal sample. Also known as: Paragonimiasis \| Pulmonary distomiasis \| Parasitic haemoptysis \| Oriental lung fluke disease \| Endemic haemoptysis Includes: lung fluke disease \| infection due to paragonimus species \| Infestation due to Paragonimus species [1F6F] Trichostrongyliasis Definition: A disease caused by an infection with the parasitic worm Trichostrongylus. This disease is characterised by abdominal pain, diarrhoea, weight loss, or may be asymptomatic. Transmission is by ingestion of contaminated food or water. Confirmation is by identification of Trichostrongylus eggs in a faecal sample. Also known as: Trichostrongyliasis \| trichostrongylosis \| infection by trichostrongylus \| infection by trichostrongylus species \| trichostrongylus infestation [1F86.Z] Schistosomiasis due to unspecified or unknown Schistosoma species Also known as: Schistosomiasis due to unspecified or unknown Schistosoma species \| Schistosomiasis \| Bilharziasis \| snail fever \| acute schistosomiasis [1C1B.Y] Other specified forms of nocardiosis Also known as: Other specified forms of nocardiosis \| Encephalitis due to Nocardia species \| Meningitis due to Nocardia species [1B91] Leptospirosis Definition: A disease caused by an infection with the gram-negative bacteria Leptospira. In the first phase, this disease is characterised by generalised illness (fever, chills, or myalgias) or individuals may be asymptomatic; in the second phase, the heart, liver, kidneys, or brain may be affected by the infection (symptoms are dependent on the site affected). Transmission is by ingestion of contaminated food or water, droplet transmission, or direct cutaneous contact. Confirmation is by identification of Also known as: Leptospirosis \| Nanukayami disease \| Nanukayami fever \| seven-day fever \| EIA - [equine infectious anaemia] === GRAPH WALKS === --- Walk 1 --- [1A01] Intestinal infection due to other Vibrio --PARENT--> [?] Bacterial intestinal infections Def: Any condition of the intestines, caused by an infection with a bacterial source.... --EXCLUDES--> [?] Bacterial foodborne intoxications Def: Any condition caused by an intoxication due to a bacterial toxin. Intoxication is by ingestion of contaminated food.... --- Walk 2 --- [1A01] Intestinal infection due to other Vibrio --PARENT--> [?] Bacterial intestinal infections Def: Any condition of the intestines, caused by an infection with a bacterial source.... --EXCLUDES--> [?] Bacterial foodborne intoxications Def: Any condition caused by an intoxication due to a bacterial toxin. Intoxication is by ingestion of contaminated food.... --- Walk 3 --- [MG50.BZ] Vibrio resistant to unspecified antibiotic --PARENT--> [MG50.B] Antibiotic resistant Vibrio --CHILD--> [MG50.B0] Fluoroquinolone resistant Vibrio --- Walk 4 --- [MG50.BZ] Vibrio resistant to unspecified antibiotic --PARENT--> [MG50.B] Antibiotic resistant Vibrio --CHILD--> [MG50.B0] Fluoroquinolone resistant Vibrio --- Walk 5 --- [MG50.BY] Vibrio resistant to other antibiotic --PARENT--> [MG50.B] Antibiotic resistant Vibrio --CHILD--> [MG50.B0] Fluoroquinolone resistant Vibrio --- Walk 6 --- [MG50.BY] Vibrio resistant to other antibiotic --PARENT--> [MG50.B] Antibiotic resistant Vibrio --CHILD--> [MG50.B0] Fluoroquinolone resistant Vibrio	[ "[1A01] Intestinal infection due to other Vibrio\n --PARENT--> [?] Bacterial intestinal infections\n Def: Any condition of the intestines, caused by an infection with a bacterial source....\n --EXCLUDES--> [?] Bacterial foodborne intoxications\n Def: Any condition caused by an intoxication due to a bacterial toxin. Intoxication is by ingestion of contaminated food....", "[1A01] Intestinal infection due to other Vibrio\n --PARENT--> [?] Bacterial intestinal infections\n Def: Any condition of the intestines, caused by an infection with a bacterial source....\n --EXCLUDES--> [?] Bacterial foodborne intoxications\n Def: Any condition caused by an intoxication due to a bacterial toxin. Intoxication is by ingestion of contaminated food....", "[MG50.BZ] Vibrio resistant to unspecified antibiotic\n --PARENT--> [MG50.B] Antibiotic resistant Vibrio\n --CHILD--> [MG50.B0] Fluoroquinolone resistant Vibrio", "[MG50.BZ] Vibrio resistant to unspecified antibiotic\n --PARENT--> [MG50.B] Antibiotic resistant Vibrio\n --CHILD--> [MG50.B0] Fluoroquinolone resistant Vibrio", "[MG50.BY] Vibrio resistant to other antibiotic\n --PARENT--> [MG50.B] Antibiotic resistant Vibrio\n --CHILD--> [MG50.B0] Fluoroquinolone resistant Vibrio", "[MG50.BY] Vibrio resistant to other antibiotic\n --PARENT--> [MG50.B] Antibiotic resistant Vibrio\n --CHILD--> [MG50.B0] Fluoroquinolone resistant Vibrio" ]	1A01	Intestinal infection due to other Vibrio	[ { "from_icd11": "1A01", "icd10_code": "A00-A09", "icd10_title": "" }, { "from_icd11": "1A01", "icd10_code": "A04", "icd10_title": "Other bacterial intestinal infections" }, { "from_icd11": "MG50.BZ", "icd10_code": "U82", "icd10_title": "" }, { "from_icd11": "MG50.BZ", "icd10_code": "U829", "icd10_title": "" }, { "from_icd11": "MG50.BZ", "icd10_code": "U83", "icd10_title": "" }, { "from_icd11": "MG50.BZ", "icd10_code": "U837", "icd10_title": "" }, { "from_icd11": "MG50.BZ", "icd10_code": "U839", "icd10_title": "" }, { "from_icd11": "1F85", "icd10_code": "B664", "icd10_title": "Paragonimiasis" }, { "from_icd11": "1F6F", "icd10_code": "B812", "icd10_title": "Trichostrongyliasis" }, { "from_icd11": "1F86.Z", "icd10_code": "B659", "icd10_title": "Schistosomiasis, unspecified" }, { "from_icd11": "1F86.Z", "icd10_code": "B658", "icd10_title": "Other schistosomiasis" }, { "from_icd11": "1F86.Z", "icd10_code": "B65", "icd10_title": "Schistosomiasis [bilharziasis]" }, { "from_icd11": "1B91", "icd10_code": "A279", "icd10_title": "Leptospirosis, unspecified" }, { "from_icd11": "1B91", "icd10_code": "A27", "icd10_title": "Leptospirosis" }, { "from_icd11": "1B91", "icd10_code": "A270", "icd10_title": "Leptospirosis icterohemorrhagica" } ]	A00-A09
The patient was started on hydroxyurea for the management of her symptoms; however, even with a subsequent increase in the dose of hydroxyurea that reached 1.5 g twice daily, her WBC count remained challenging to manage. Therefore, treatment with a hypomethylating agent with decitabine at 20 mg/m 2 , Monday to Friday, was initiated in addition to continuation with hydroxyurea. Despite receiving a total of four cycles of decitabine in addition to hydroxyurea, she continued to have persistent anemia requiring blood transfusions. Repeated bone marrow biopsy showed dysmyelopoiesis and fibrosis with 13% blasts and, therefore, venetoclax was added to the regimen. The patient remained on venetoclax, hydroxyurea, and decitabine for approximately four months. The decision was made to discontinue venetoclax and hydroxyurea due to the patient’s worsening anemia thrombocytopenia, increasing blasts, and development of cardiac toxicity from venetoclax in the form of pericardial effusion and non-ischemic cardiomyopathy. Following six cycles of decitabine, and considering she harbored NRAS mutation based on the NGS result, she was ultimately started on a mitogen-activated protein kinase kinase (MEK) inhibitor, trametinib (2 mg), once daily only. Her blood counts subsequently stabilized, and she began to feel better and less fatigued. She did not require any blood transfusions for four months while on this therapy.	3.828125	0.973633	sec[1]/p[3]	en	0.999999	PMC9356656	https://doi.org/10.7759/cureus.26619	[ "hydroxyurea", "decitabine", "venetoclax", "four", "blood", "daily", "remained", "therefore", "addition", "cycles" ]	[ { "code": "LD50.Y", "title": "Other specified number anomalies of chromosome X" }, { "code": "NA82.4", "title": "Multiple fractures of ribs" }, { "code": "BA4Z", "title": "Acute ischaemic heart disease, unspecified" }, { "code": "3C0Z", "title": "Diseases of the blood or blood-forming organs, unspecified" }, { "code": "MF50.4Z", "title": "Haematuria, unspecified" }, { "code": "MA12.1", "title": "Finding of cocaine in blood" }, { "code": "MA12.4", "title": "Finding of steroid agent in blood" }, { "code": "MA12.2", "title": "Finding of hallucinogen in blood" }, { "code": "QF21", "title": "Difficulty or need for assistance with general life tasks or life management" }, { "code": "8A83", "title": "Other primary headache disorder" } ]	=== ICD-11 CODES FOUND === [LD50.Y] Other specified number anomalies of chromosome X Also known as: Other specified number anomalies of chromosome X \| Female with more than three X chromosomes \| abnormal female chromosomes, with more than three x chromosomes \| Tetrasomy X \| 48 xxxx syndrome [NA82.4] Multiple fractures of ribs Also known as: Multiple fractures of ribs \| rib fractures \| Multiple rib fractures, involving first rib \| Multiple rib fractures, involving two ribs \| Multiple rib fractures, involving three ribs [BA4Z] Acute ischaemic heart disease, unspecified Also known as: Acute ischaemic heart disease, unspecified \| acute coronary syndrome \| ACS - [acute coronary syndrome] \| Silent myocardial ischaemia \| asymptomatic ischemia [3C0Z] Diseases of the blood or blood-forming organs, unspecified Also known as: Diseases of the blood or blood-forming organs, unspecified \| Blood, lymph or spleen disease \| blood condition NOS \| blood disorder NOS \| bone marrow disease NOS [MF50.4Z] Haematuria, unspecified Also known as: Haematuria, unspecified \| Haematuria \| blood in urine \| urinary blood \| haematuria NOS [MA12.1] Finding of cocaine in blood Also known as: Finding of cocaine in blood \| cocaine in blood [MA12.4] Finding of steroid agent in blood Also known as: Finding of steroid agent in blood \| steroid in blood [MA12.2] Finding of hallucinogen in blood Also known as: Finding of hallucinogen in blood \| hallucinogen in blood [QF21] Difficulty or need for assistance with general life tasks or life management Also known as: Difficulty or need for assistance with general life tasks or life management \| difficulty with carrying out tasks and daily routine \| life management problem \| difficulty with life management tasks \| Difficulty with dealing with change such as relocation Includes: difficulty with carrying out tasks and daily routine [8A83] Other primary headache disorder Definition: A group of clinically heterogeneous headache disorders, believed to be primary. Although largely unrelated, they fall into four categories: headaches associated with physical exertion; headaches attributed to direct physical but innocuous stimuli; epicranial headaches; and other miscellaneous primary headache disorders. Also known as: Other primary headache disorder \| Primary cough headache \| Primary exercise headache \| Primary headache associated with sexual activity \| Preorgasmic headache === GRAPH WALKS === --- Walk 1 --- [LD50.Y] Other specified number anomalies of chromosome X --PARENT--> [LD50] Number anomalies of chromosome X --CHILD--> [LD50.0] Turner syndrome Def: Karyotype missing one X chromosome (45,X0 or 45,X0/46,XX mosaicism); gonads: ovaries (streak); phenotype female with short stature, amenorrhea (hypergonadotropic hypogonadism), absence of sexual devel... --- Walk 2 --- [LD50.Y] Other specified number anomalies of chromosome X --PARENT--> [LD50] Number anomalies of chromosome X --CHILD--> [LD50.1] Karyotype 47,XXX Def: Trisomy X is a sex chromosome anomaly with a variable phenotype caused by the presence of an extra X chromosome in females (47,XXX instead of 46,XX). Most individuals are only mildly affected or asymp... --- Walk 3 --- [NA82.4] Multiple fractures of ribs --PARENT--> [NA82] Fracture of rib, sternum or thoracic spine --CHILD--> [NA82.2] Fracture of sternum --- Walk 4 --- [NA82.4] Multiple fractures of ribs --PARENT--> [NA82] Fracture of rib, sternum or thoracic spine --CHILD--> [NA82.2] Fracture of sternum --- Walk 5 --- [BA4Z] Acute ischaemic heart disease, unspecified --PARENT--> [?] Acute ischaemic heart disease --PARENT--> [?] Ischaemic heart diseases --- Walk 6 --- [BA4Z] Acute ischaemic heart disease, unspecified --PARENT--> [?] Acute ischaemic heart disease --PARENT--> [?] Ischaemic heart diseases	[ "[LD50.Y] Other specified number anomalies of chromosome X\n --PARENT--> [LD50] Number anomalies of chromosome X\n --CHILD--> [LD50.0] Turner syndrome\n Def: Karyotype missing one X chromosome (45,X0 or 45,X0/46,XX mosaicism); gonads: ovaries (streak); phenotype female with short stature, amenorrhea (hypergonadotropic hypogonadism), absence of sexual devel...", "[LD50.Y] Other specified number anomalies of chromosome X\n --PARENT--> [LD50] Number anomalies of chromosome X\n --CHILD--> [LD50.1] Karyotype 47,XXX\n Def: Trisomy X is a sex chromosome anomaly with a variable phenotype caused by the presence of an extra X chromosome in females (47,XXX instead of 46,XX). Most individuals are only mildly affected or asymp...", "[NA82.4] Multiple fractures of ribs\n --PARENT--> [NA82] Fracture of rib, sternum or thoracic spine\n --CHILD--> [NA82.2] Fracture of sternum", "[NA82.4] Multiple fractures of ribs\n --PARENT--> [NA82] Fracture of rib, sternum or thoracic spine\n --CHILD--> [NA82.2] Fracture of sternum", "[BA4Z] Acute ischaemic heart disease, unspecified\n --PARENT--> [?] Acute ischaemic heart disease\n --PARENT--> [?] Ischaemic heart diseases", "[BA4Z] Acute ischaemic heart disease, unspecified\n --PARENT--> [?] Acute ischaemic heart disease\n --PARENT--> [?] Ischaemic heart diseases" ]	LD50.Y	Other specified number anomalies of chromosome X	[ { "from_icd11": "NA82.4", "icd10_code": "S2249XA", "icd10_title": "Multiple fractures of ribs, unspecified side, initial encounter for closed fracture" }, { "from_icd11": "NA82.4", "icd10_code": "S2243XD", "icd10_title": "Multiple fractures of ribs, bilateral, subsequent encounter for fracture with routine healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2241XS", "icd10_title": "Multiple fractures of ribs, right side, sequela" }, { "from_icd11": "NA82.4", "icd10_code": "S2249XD", "icd10_title": "Multiple fractures of ribs, unspecified side, subsequent encounter for fracture with routine healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2243XS", "icd10_title": "Multiple fractures of ribs, bilateral, sequela" }, { "from_icd11": "NA82.4", "icd10_code": "S2249XS", "icd10_title": "Multiple fractures of ribs, unspecified side, sequela" }, { "from_icd11": "NA82.4", "icd10_code": "S2249XG", "icd10_title": "Multiple fractures of ribs, unspecified side, subsequent encounter for fracture with delayed healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2243XG", "icd10_title": "Multiple fractures of ribs, bilateral, subsequent encounter for fracture with delayed healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2241XG", "icd10_title": "Multiple fractures of ribs, right side, subsequent encounter for fracture with delayed healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2242XG", "icd10_title": "Multiple fractures of ribs, left side, subsequent encounter for fracture with delayed healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2249XB", "icd10_title": "Multiple fractures of ribs, unspecified side, initial encounter for open fracture" }, { "from_icd11": "NA82.4", "icd10_code": "S2242XA", "icd10_title": "Multiple fractures of ribs, left side, initial encounter for closed fracture" }, { "from_icd11": "NA82.4", "icd10_code": "S2243XA", "icd10_title": "Multiple fractures of ribs, bilateral, initial encounter for closed fracture" }, { "from_icd11": "NA82.4", "icd10_code": "S2241XD", "icd10_title": "Multiple fractures of ribs, right side, subsequent encounter for fracture with routine healing" }, { "from_icd11": "NA82.4", "icd10_code": "S2241XA", "icd10_title": "Multiple fractures of ribs, right side, initial encounter for closed fracture" } ]	S2249XA	Multiple fractures of ribs, unspecified side, initial encounter for closed fracture
A 23-year-old man presented to the Emergency Department of our hospital with a 1-month history of pneumaturia, fecaluria, and mild abdominal pain on the right inferior abdominal quadrant. He referred that, one week earlier, he experienced an episode of macroematuria with no fever and regular bowel function. He was sent to Urological Department for a consultation. His clinical history was characterized only by appendectomy and a right hernioplasty that dated back to 3 years earlier with no complication. He had no history of chronic inflammatory disease of the bowels or mental disease. Examination revealed only a right lower abdominal pain during deep palpation. An ultrasound scan of the abdomen showed a hyperechoic rim on the right wall of the bladder, but it was not considered relevant. Cystoscopy showed two relatively small inflamed areas on the right anterolateral wall of bladder. Cystography, after a refilling of 500 mL, looked normal . A CT of the pelvis revealed a threadlike element, probably a foreign body (length 6.5 cm and diameter 1–1.5 mm), angled in its caudal part. A tip of the foreign body was in the right anterolateral wall of bladder and the other one was in a pelvic loop of the sigmoid colon without any signs of abscess or fistula . After CT the patient referred that he accidentally swallowed a toothpick two years earlier with no consequent complications and then he forgot about it.	3.742188	0.986816	sec[1]/p[0]	en	0.999997	25838964	https://doi.org/10.1155/2015/902673	[ "abdominal", "that", "wall", "bladder", "department", "pain", "referred", "anterolateral", "foreign", "body" ]	[ { "code": "MD81.3", "title": "Acute abdomen" }, { "code": "JA01.0", "title": "Abdominal pregnancy" }, { "code": "ME04.Z", "title": "Ascites, unspecified" }, { "code": "NB51.0&XA3KX0", "title": "Laceration without foreign body of abdominal wall" }, { "code": "NB9Y", "title": "Other specified injuries to the abdomen, lower back, lumbar spine or pelvis" }, { "code": "8A80.Z", "title": "Migraine, unspecified" }, { "code": "QA76", "title": "Medication or substance that is known to be an allergen without injury or harm" }, { "code": "PL13.6", "title": "Medication or substance that is known to be an allergen, as mode of injury or harm" }, { "code": "9C40.A0", "title": "Papilloedema" }, { "code": "PA6Z", "title": "Unintentional fall from unspecified height" } ]	=== ICD-11 CODES FOUND === [MD81.3] Acute abdomen Definition: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases Also known as: Acute abdomen \| acute abdominal pain syndrome \| surgical abdomen \| abdominal acute syndrome \| severe abdomen pain [JA01.0] Abdominal pregnancy Definition: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy. Also known as: Abdominal pregnancy \| abdomen pregnancy \| intraperitoneal pregnancy Excludes: Maternal care for viable fetus in abdominal pregnancy \| Delivery of viable fetus in abdominal pregnancy [ME04.Z] Ascites, unspecified Also known as: Ascites, unspecified \| Ascites \| abdominal dropsy \| hydrops abdominis \| ascites NOS [NB9Y] Other specified injuries to the abdomen, lower back, lumbar spine or pelvis Also known as: Other specified injuries to the abdomen, lower back, lumbar spine or pelvis \| Abdominal wall trauma \| Injury of pelvic floor \| pelvic floor blunt injury \| pelvic floor blunt trauma [8A80.Z] Migraine, unspecified Also known as: Migraine, unspecified \| Migraine [QA76] Medication or substance that is known to be an allergen without injury or harm Definition: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm. Also known as: Medication or substance that is known to be an allergen without injury or harm Excludes: Medication or substance that is known to be an allergen, as mode of injury or harm [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm Also known as: Medication or substance that is known to be an allergen, as mode of injury or harm \| medication error relating to known allergy to drug or substance \| adverse drug event relating to known allergy to drug or substance [9C40.A0] Papilloedema Definition: Optic disc swelling that results from increased intracranial pressure Also known as: Papilloedema \| Optic disc swelling that results from increased intracranial pressure Includes: Optic disc swelling that results from increased intracranial pressure [PA6Z] Unintentional fall from unspecified height Also known as: Unintentional fall from unspecified height \| fall NOS \| accidental fall \| fall causing injury that resulted in death \| fell NOS === GRAPH WALKS === --- Walk 1 --- [MD81.3] Acute abdomen Def: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases... --PARENT--> [MD81] Abdominal or pelvic pain Def: Pain, an unpleasant distress sensation occurring in varying degrees of severity, received by nerve ending in the abdominal and pelvic region.... --CHILD--> [MD81.0] Abdominal tenderness --- Walk 2 --- [MD81.3] Acute abdomen Def: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases... --PARENT--> [MD81] Abdominal or pelvic pain Def: Pain, an unpleasant distress sensation occurring in varying degrees of severity, received by nerve ending in the abdominal and pelvic region.... --EXCLUDES--> [?] Spinal pain Def: This is a condition characterised by pain felt in the back that usually originates from the muscles, nerves, bones, joints or other structures in the spine.... --- Walk 3 --- [JA01.0] Abdominal pregnancy Def: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy.... --EXCLUDES--> [?] Delivery of viable fetus in abdominal pregnancy Def: A condition caused by the development of a viable fetus to the culmination of the pregnancy period. This condition is characterised by parturition of a viable neonate from the abdominal cavity, at the... --PARENT--> [?] Other assisted single delivery --- Walk 4 --- [JA01.0] Abdominal pregnancy Def: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy.... --EXCLUDES--> [?] Delivery of viable fetus in abdominal pregnancy Def: A condition caused by the development of a viable fetus to the culmination of the pregnancy period. This condition is characterised by parturition of a viable neonate from the abdominal cavity, at the... --PARENT--> [?] Other assisted single delivery --- Walk 5 --- [ME04.Z] Ascites, unspecified --PARENT--> [ME04] Ascites Def: Accumulation or retention of free fluid in the abdominal peritoneal cavity between the tissues lining the abdomen and abdominal organs. The fluid may be serous, haemorrhagic, or the result of inflamma... --CHILD--> [ME04.0] Fluid in peritoneal cavity --- Walk 6 --- [ME04.Z] Ascites, unspecified --PARENT--> [ME04] Ascites Def: Accumulation or retention of free fluid in the abdominal peritoneal cavity between the tissues lining the abdomen and abdominal organs. The fluid may be serous, haemorrhagic, or the result of inflamma... --CHILD--> [ME04.Z] Ascites, unspecified	[ "[MD81.3] Acute abdomen\n Def: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases...\n --PARENT--> [MD81] Abdominal or pelvic pain\n Def: Pain, an unpleasant distress sensation occurring in varying degrees of severity, received by nerve ending in the abdominal and pelvic region....\n --CHILD--> [MD81.0] Abdominal tenderness", "[MD81.3] Acute abdomen\n Def: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases...\n --PARENT--> [MD81] Abdominal or pelvic pain\n Def: Pain, an unpleasant distress sensation occurring in varying degrees of severity, received by nerve ending in the abdominal and pelvic region....\n --EXCLUDES--> [?] Spinal pain\n Def: This is a condition characterised by pain felt in the back that usually originates from the muscles, nerves, bones, joints or other structures in the spine....", "[JA01.0] Abdominal pregnancy\n Def: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy....\n --EXCLUDES--> [?] Delivery of viable fetus in abdominal pregnancy\n Def: A condition caused by the development of a viable fetus to the culmination of the pregnancy period. This condition is characterised by parturition of a viable neonate from the abdominal cavity, at the...\n --PARENT--> [?] Other assisted single delivery", "[JA01.0] Abdominal pregnancy\n Def: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy....\n --EXCLUDES--> [?] Delivery of viable fetus in abdominal pregnancy\n Def: A condition caused by the development of a viable fetus to the culmination of the pregnancy period. This condition is characterised by parturition of a viable neonate from the abdominal cavity, at the...\n --PARENT--> [?] Other assisted single delivery", "[ME04.Z] Ascites, unspecified\n --PARENT--> [ME04] Ascites\n Def: Accumulation or retention of free fluid in the abdominal peritoneal cavity between the tissues lining the abdomen and abdominal organs. The fluid may be serous, haemorrhagic, or the result of inflamma...\n --CHILD--> [ME04.0] Fluid in peritoneal cavity", "[ME04.Z] Ascites, unspecified\n --PARENT--> [ME04] Ascites\n Def: Accumulation or retention of free fluid in the abdominal peritoneal cavity between the tissues lining the abdomen and abdominal organs. The fluid may be serous, haemorrhagic, or the result of inflamma...\n --CHILD--> [ME04.Z] Ascites, unspecified" ]	MD81.3	Acute abdomen	[ { "from_icd11": "MD81.3", "icd10_code": "R100", "icd10_title": "Acute abdomen" }, { "from_icd11": "JA01.0", "icd10_code": "O0000", "icd10_title": "Abdominal pregnancy without intrauterine pregnancy" }, { "from_icd11": "JA01.0", "icd10_code": "O000", "icd10_title": "Abdominal pregnancy" }, { "from_icd11": "ME04.Z", "icd10_code": "R180", "icd10_title": "Malignant ascites" }, { "from_icd11": "ME04.Z", "icd10_code": "R18", "icd10_title": "Ascites" }, { "from_icd11": "8A80.Z", "icd10_code": "G43B0", "icd10_title": "Ophthalmoplegic migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43409", "icd10_title": "Hemiplegic migraine, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A0", "icd10_title": "Cyclical vomiting, in migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43D0", "icd10_title": "Abdominal migraine, not intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43709", "icd10_title": "Chronic migraine without aura, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43A1", "icd10_title": "Cyclical vomiting, in migraine, intractable" }, { "from_icd11": "8A80.Z", "icd10_code": "G43509", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43719", "icd10_title": "Chronic migraine without aura, intractable, without status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43501", "icd10_title": "Persistent migraine aura without cerebral infarction, not intractable, with status migrainosus" }, { "from_icd11": "8A80.Z", "icd10_code": "G43C0", "icd10_title": "Periodic headache syndromes in child or adult, not intractable" } ]	R100	Acute abdomen
Scenario 1: Charlie is 5 years old, has spastic quadriplegia and a cortical vision impairment. His parents have set a goal of walking independently. During his most recent physiotherapy sessions Charlie has been working on head control by sitting on a slowly moving ball and practicing lifting his head in prone, over a roller. To assess whether the goal of walking is realistic, the current team assess Charlie in detail with the Gross Motor Function Measure (GMFM-66), where he is then classified on the Gross Motor Function Classification Scale (GMFCS) as level V (i.e., non-ambulant). Additionally, his ability to use his hands is assessed using the Manual Ability Classification Scale (MACS), and scored as level IV. A prognostic conversation is then planned, and it is compassionately explained at the family meeting that for children who are functioning at GMFCS level V, and are already 5 years of age, walking independently is an extremely unlikely outcome. They explain that children with this level of cerebral palsy typically reach 90% of their motor potential by 3 years of age. The team then explores with the family the hopes they have for Charlie to be able to access his environment in the context of limited independence. The goals are readjusted to include changing position in bed with less assistance and exploring suitable wheeled mobility options to support Charlie's inclusion in all environments.	3.722656	0.95166	sec[2]/sec[2]/p[1]	en	0.999997	36188787	https://doi.org/10.3389/fresc.2021.726410	[ "charlie", "walking", "motor", "goal", "independently", "head", "assess", "team", "gross", "function" ]	[ { "code": "LD25.0Y", "title": "Other specified oromandibular-limb anomaly syndrome" }, { "code": "MB44.2", "title": "Difficulty in walking" }, { "code": "PA82", "title": "Unintentional striking against stationary object" }, { "code": "7B00.1", "title": "Sleepwalking disorder" }, { "code": "BA40.1", "title": "Stable angina" }, { "code": "QF23", "title": "Difficulty or need for assistance with mobility" }, { "code": "MB47.0", "title": "Abnormal reflex" }, { "code": "PA2Z", "title": "Unintentional land transport injury event unknown whether traffic or nontraffic injuring a user of unspecified transport" }, { "code": "DA21.Z", "title": "Motility disorders of oesophagus, unspecified" }, { "code": "PA03", "title": "Unintentional land transport traffic event injuring a motor cyclist" } ]	=== ICD-11 CODES FOUND === [LD25.0Y] Other specified oromandibular-limb anomaly syndrome Also known as: Other specified oromandibular-limb anomaly syndrome \| Oromandibular-limb hypogenesis syndrome \| Charlie M syndrome \| Hypoglossia - hypodactyly \| Glossopalatine ankylosis [MB44.2] Difficulty in walking Also known as: Difficulty in walking \| difficult walking \| dysbasia [PA82] Unintentional striking against stationary object Also known as: Unintentional striking against stationary object \| striking against stationary object \| striking against or struck by other objects \| Walked into wall [7B00.1] Sleepwalking disorder Definition: Sleepwalking disorder is characterised by ambulation and other complex behaviours during a partial arousal from deep sleep. Also known as: Sleepwalking disorder \| sleep walking \| sleepwalking \| somnambulism \| sleep walking disorder [BA40.1] Stable angina Also known as: Stable angina \| walk-through angina [QF23] Difficulty or need for assistance with mobility Also known as: Difficulty or need for assistance with mobility \| difficulty with mobility \| need for assistance due to reduced mobility \| need for assistance with mobility \| problem with impaired mobility Excludes: Abnormalities of gait or mobility [MB47.0] Abnormal reflex Also known as: Abnormal reflex \| reflex disorder \| reflex disturbance \| motor disturbance \| motor disorder Excludes: vasovagal reaction or syncope \| hyperactive gag reflex \| abnormal pupillary reflex [PA2Z] Unintentional land transport injury event unknown whether traffic or nontraffic injuring a user of unspecified transport Also known as: Unintentional land transport injury event unknown whether traffic or nontraffic injuring a user of unspecified transport \| unintentional land transport injury event unknown whether on road or off-road \| land transport accident NOS \| motor vehicle accident NOS \| MVA - [motor vehicle accident] NOS [DA21.Z] Motility disorders of oesophagus, unspecified Also known as: Motility disorders of oesophagus, unspecified \| Motility disorders of oesophagus \| Dyskinesia of oesophagus \| oesophageal dysmotility \| oesophageal motility disorder [PA03] Unintentional land transport traffic event injuring a motor cyclist Also known as: Unintentional land transport traffic event injuring a motor cyclist \| motorcycle rider injured in transport accident \| unintentional land transport accident motorbike \| motorbike accident \| motorbike traffic accident Excludes: Unintentional land transport traffic event injuring an occupant of a low powered passenger vehicle === GRAPH WALKS === --- Walk 1 --- [LD25.0Y] Other specified oromandibular-limb anomaly syndrome --PARENT--> [LD25.0] Oromandibular-limb anomaly syndrome Def: A syndrome caused by failure of the face and limbs to correctly develop during the antenatal period. This syndrome is characterised by malformations of the tongue, mandible, and limbs.... --EXCLUDES--> [?] Ectrodactyly - cleft palate Def: Ectrodactyly - cleft palate is the association of monodactylous ectrodactyly and cleft palate. Lack of cleft lip and ectodermal dysplasia makes it different from EEC syndrome .... --- Walk 2 --- [LD25.0Y] Other specified oromandibular-limb anomaly syndrome --PARENT--> [LD25.0] Oromandibular-limb anomaly syndrome Def: A syndrome caused by failure of the face and limbs to correctly develop during the antenatal period. This syndrome is characterised by malformations of the tongue, mandible, and limbs.... --CHILD--> [LD25.0Y] Other specified oromandibular-limb anomaly syndrome --- Walk 3 --- [MB44.2] Difficulty in walking --PARENT--> [MB44] Abnormalities of gait or mobility Def: Abnormalities of gait or mobility include ataxic gait, paralytic gait, difficulty in walking, immobility, and other abnormalities of gait or mobility.... --CHILD--> [MB44.1] Paralytic gait Def: A collection of gait abnormalities due to affected motor control, sensory feedback, and muscle strength.... --- Walk 4 --- [MB44.2] Difficulty in walking --PARENT--> [MB44] Abnormalities of gait or mobility Def: Abnormalities of gait or mobility include ataxic gait, paralytic gait, difficulty in walking, immobility, and other abnormalities of gait or mobility.... --EXCLUDES--> [?] Hereditary ataxia Def: A group of genetic disorders characterised by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements... --- Walk 5 --- [PA82] Unintentional striking against stationary object --PARENT--> [?] Unintentional exposure to object, not elsewhere classified --CHILD--> [PA81] Unintentionally struck by moving object --- Walk 6 --- [PA82] Unintentional striking against stationary object --PARENT--> [?] Unintentional exposure to object, not elsewhere classified --CHILD--> [PA81] Unintentionally struck by moving object	[ "[LD25.0Y] Other specified oromandibular-limb anomaly syndrome\n --PARENT--> [LD25.0] Oromandibular-limb anomaly syndrome\n Def: A syndrome caused by failure of the face and limbs to correctly develop during the antenatal period. This syndrome is characterised by malformations of the tongue, mandible, and limbs....\n --EXCLUDES--> [?] Ectrodactyly - cleft palate\n Def: Ectrodactyly - cleft palate is the association of monodactylous ectrodactyly and cleft palate. Lack of cleft lip and ectodermal dysplasia makes it different from EEC syndrome ....", "[LD25.0Y] Other specified oromandibular-limb anomaly syndrome\n --PARENT--> [LD25.0] Oromandibular-limb anomaly syndrome\n Def: A syndrome caused by failure of the face and limbs to correctly develop during the antenatal period. This syndrome is characterised by malformations of the tongue, mandible, and limbs....\n --CHILD--> [LD25.0Y] Other specified oromandibular-limb anomaly syndrome", "[MB44.2] Difficulty in walking\n --PARENT--> [MB44] Abnormalities of gait or mobility\n Def: Abnormalities of gait or mobility include ataxic gait, paralytic gait, difficulty in walking, immobility, and other abnormalities of gait or mobility....\n --CHILD--> [MB44.1] Paralytic gait\n Def: A collection of gait abnormalities due to affected motor control, sensory feedback, and muscle strength....", "[MB44.2] Difficulty in walking\n --PARENT--> [MB44] Abnormalities of gait or mobility\n Def: Abnormalities of gait or mobility include ataxic gait, paralytic gait, difficulty in walking, immobility, and other abnormalities of gait or mobility....\n --EXCLUDES--> [?] Hereditary ataxia\n Def: A group of genetic disorders characterised by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements...", "[PA82] Unintentional striking against stationary object\n --PARENT--> [?] Unintentional exposure to object, not elsewhere classified\n --CHILD--> [PA81] Unintentionally struck by moving object", "[PA82] Unintentional striking against stationary object\n --PARENT--> [?] Unintentional exposure to object, not elsewhere classified\n --CHILD--> [PA81] Unintentionally struck by moving object" ]	LD25.0Y	Other specified oromandibular-limb anomaly syndrome	[ { "from_icd11": "MB44.2", "icd10_code": "R262", "icd10_title": "Difficulty in walking, not elsewhere classified" }, { "from_icd11": "PA82", "icd10_code": "W2209XA", "icd10_title": "Striking against other stationary object, initial encounter" }, { "from_icd11": "PA82", "icd10_code": "W2201XA", "icd10_title": "Walked into wall, initial encounter" }, { "from_icd11": "PA82", "icd10_code": "W2211XA", "icd10_title": "Striking against or struck by driver side automobile airbag, initial encounter" }, { "from_icd11": "PA82", "icd10_code": "W228XXS", "icd10_title": "Striking against or struck by other objects, sequela" }, { "from_icd11": "PA82", "icd10_code": "W2203XD", "icd10_title": "Walked into furniture, subsequent encounter" }, { "from_icd11": "PA82", "icd10_code": "W2203XA", "icd10_title": "Walked into furniture, initial encounter" }, { "from_icd11": "PA82", "icd10_code": "W228XXD", "icd10_title": "Striking against or struck by other objects, subsequent encounter" }, { "from_icd11": "PA82", "icd10_code": "W2212XA", "icd10_title": "Striking against or struck by front passenger side automobile airbag, initial encounter" }, { "from_icd11": "PA82", "icd10_code": "W2209XS", "icd10_title": "Striking against other stationary object, sequela" }, { "from_icd11": "PA82", "icd10_code": "W228XXA", "icd10_title": "Striking against or struck by other objects, initial encounter" }, { "from_icd11": "PA82", "icd10_code": "W22", "icd10_title": "Striking against or struck by other objects" }, { "from_icd11": "7B00.1", "icd10_code": "F513", "icd10_title": "Sleepwalking [somnambulism]" }, { "from_icd11": "QF23", "icd10_code": "Z7401", "icd10_title": "Bed confinement status" }, { "from_icd11": "QF23", "icd10_code": "Z7409", "icd10_title": "Other reduced mobility" } ]	R262	Difficulty in walking, not elsewhere classified
Contrast-enhanced computed tomography (CECT) scan of the thorax, abdomen, and pelvis showed a large heterogeneously enhancing pelvic mass 9x5.8x7.4 cm involving bilateral adnexa with multiple large peritoneal, intrahepatic, and splenic deposits, along with gross ascites and nodularity of omentum and peritoneum. Omental biopsy was reported as metastatic immature teratoma. The patient received two cycles of chemotherapy with a three-week BEP regime (Bleomycin 30 units IV weekly, Etoposide 100 mg/m2 IV day 1-5 and Cisplatin 20 mg/m2 IV day 1-5). She developed progressive, linear hyperpigmented streaks involving the upper back, arm, and abdomen associated with itching after the second cycle of chemotherapy. The third cycle of chemotherapy was deferred as the patient had increasing abdominal distention, and imaging was suggestive of progressive disease; however, tumour markers decreased markedly. A repeat biopsy from the liver deposit and adnexal mass was reported as mature teratoma, and a diagnosis of growing teratoma syndrome was made. She was prescribed topical emollient cream for local application and oral tablet levocetirizine daily for a week for the pruritis. The lesions disappeared completely after stopping bleomycin therapy within six months . The patient underwent extensive cytoreductive surgery for the growing teratoma syndrome and is currently under follow-up and disease-free for six months.	3.865234	0.97998	sec[1]/p[1]	en	0.999997	PMC9571210	https://doi.org/10.7759/cureus.29221	[ "teratoma", "chemotherapy", "abdomen", "large", "involving", "biopsy", "bleomycin", "cycle", "growing", "contrast" ]	[ { "code": "2F32.0", "title": "Cystic teratoma" }, { "code": "2F00.Y", "title": "Other specified benign neoplasm of middle ear or respiratory system" }, { "code": "2A00.1Y", "title": "Other specified embryonal tumours of brain" }, { "code": "2F32.Y", "title": "Other specified benign neoplasm of ovary" }, { "code": "2C80.2", "title": "Germ cell tumour of testis" }, { "code": "QB97", "title": "Contact with health services for chemotherapy session for neoplasm" }, { "code": "QC05.Y", "title": "Other specified prophylactic measures" }, { "code": "QB9Y", "title": "Other specified contact with health services for nonsurgical interventions not involving devices" }, { "code": "3B64.1Y", "title": "Other specified acquired thrombocytopenia" }, { "code": "QC48.Y", "title": "Other specified personal history of medical treatment" } ]	=== ICD-11 CODES FOUND === [2F32.0] Cystic teratoma Definition: A condition of the ovary, caused by abnormal proliferation due to genetic mutations, abnormal growth or division of germ cells. This condition is characterised by a benign ovarian neoplasm, and abdominal pain, mass or swelling, or abnormal uterine bleeding, and may lead to ovarian torsion or cystic rupture. Confirmation is by imaging. Also known as: Cystic teratoma [2F00.Y] Other specified benign neoplasm of middle ear or respiratory system Also known as: Other specified benign neoplasm of middle ear or respiratory system \| Benign neoplasm of middle ear, nasal cavity or accessory sinuses \| Transphenoidal adenoma \| Benign neoplasm of accessory sinus \| Benign neoplasm of cartilage of nose [2A00.1Y] Other specified embryonal tumours of brain Also known as: Other specified embryonal tumours of brain \| Atypical teratoid rhabdoid tumour of brain \| Choriocarcinoma of the central nervous system \| Germinoma of the central nervous system \| germinoma of unspecified site [2F32.Y] Other specified benign neoplasm of ovary Also known as: Other specified benign neoplasm of ovary \| Serous or mucinous ovarian cystadenoma of childhood \| Benign androblastoma of ovary \| tubular androblastoma of unspecified site, female \| Adenofibroma of ovary [2C80.2] Germ cell tumour of testis Definition: A germ cell tumour arising from the testis. Representative examples include teratoma, seminoma, embryonal carcinoma, and yolk sac tumour. Also known as: Germ cell tumour of testis \| Choriocarcinoma of testis \| choriocarcinoma of unspecified site, male \| chorionic carcinoma of unspecified site, male \| Malignant trophoblastic tumour of testis [QB97] Contact with health services for chemotherapy session for neoplasm Also known as: Contact with health services for chemotherapy session for neoplasm \| antineoplastic chemotherapy regimen \| cancer chemotherapy regimen \| maintenance chemotherapy for neoplasm \| neoplasm chemotherapy [QC05.Y] Other specified prophylactic measures Also known as: Other specified prophylactic measures \| Other prophylactic chemotherapy \| chemoprophylaxis \| prophylactic chemotherapy \| Systemic prophylactic chemotherapy [QB9Y] Other specified contact with health services for nonsurgical interventions not involving devices Also known as: Other specified contact with health services for nonsurgical interventions not involving devices \| Chemotherapy other than for neoplasm \| admission for chemotherapy administration other than for neoplasm \| chemotherapy regimen other than for neoplasm \| drug therapy other than for neoplasm [3B64.1Y] Other specified acquired thrombocytopenia Also known as: Other specified acquired thrombocytopenia \| Acquired thrombocytopenia specified as refractory \| Chemotherapy thrombocytopaenia \| Liver thrombocytopaenia [QC48.Y] Other specified personal history of medical treatment Also known as: Other specified personal history of medical treatment \| Personal history of contraception \| history of contraception \| Personal history of long-term use of medicaments other than anticoagulants \| personal history of long term current use of medicaments === GRAPH WALKS === --- Walk 1 --- [2F32.0] Cystic teratoma Def: A condition of the ovary, caused by abnormal proliferation due to genetic mutations, abnormal growth or division of germ cells. This condition is characterised by a benign ovarian neoplasm, and abdomi... --PARENT--> [2F32] Benign neoplasm of ovary Def: A non-metastasizing neoplasm that arises from the ovary. Representative examples include serous cystadenoma, mucinous cystadenoma, clear cell adenofibroma, benign Brenner tumour, thecoma, and fibroma.... --CHILD--> [2F32.0] Cystic teratoma Def: A condition of the ovary, caused by abnormal proliferation due to genetic mutations, abnormal growth or division of germ cells. This condition is characterised by a benign ovarian neoplasm, and abdomi... --- Walk 2 --- [2F32.0] Cystic teratoma Def: A condition of the ovary, caused by abnormal proliferation due to genetic mutations, abnormal growth or division of germ cells. This condition is characterised by a benign ovarian neoplasm, and abdomi... --PARENT--> [2F32] Benign neoplasm of ovary Def: A non-metastasizing neoplasm that arises from the ovary. Representative examples include serous cystadenoma, mucinous cystadenoma, clear cell adenofibroma, benign Brenner tumour, thecoma, and fibroma.... --CHILD--> [2F32.2] Meigs' syndrome Def: Meigs' syndrome is classically defined as the triad of ascites, pleural effusion, and benign ovarian fibroma. A key feature found in patients with Meigs' syndrome is the resolution of symptoms after t... --- Walk 3 --- [2F00.Y] Other specified benign neoplasm of middle ear or respiratory system --PARENT--> [2F00] Benign neoplasm of middle ear or respiratory system --CHILD--> [2F00.0] Middle ear endocrine tumour --- Walk 4 --- [2F00.Y] Other specified benign neoplasm of middle ear or respiratory system --PARENT--> [2F00] Benign neoplasm of middle ear or respiratory system --CHILD--> [2F00.1] Recurrent respiratory papillomatosis Def: Recurrent respiratory papillomatosis is a rare respiratory disease characterised by the development of exophytic papillomas, affecting the mucosa of the upper aero-digestive tract (with a strong predi... --- Walk 5 --- [2A00.1Y] Other specified embryonal tumours of brain --PARENT--> [2A00.1] Embryonal tumours of brain --PARENT--> [2A00] Primary neoplasms of brain --- Walk 6 --- [2A00.1Y] Other specified embryonal tumours of brain --PARENT--> [2A00.1] Embryonal tumours of brain --PARENT--> [2A00] Primary neoplasms of brain	[ "[2F32.0] Cystic teratoma\n Def: A condition of the ovary, caused by abnormal proliferation due to genetic mutations, abnormal growth or division of germ cells. This condition is characterised by a benign ovarian neoplasm, and abdomi...\n --PARENT--> [2F32] Benign neoplasm of ovary\n Def: A non-metastasizing neoplasm that arises from the ovary. Representative examples include serous cystadenoma, mucinous cystadenoma, clear cell adenofibroma, benign Brenner tumour, thecoma, and fibroma....\n --CHILD--> [2F32.0] Cystic teratoma\n Def: A condition of the ovary, caused by abnormal proliferation due to genetic mutations, abnormal growth or division of germ cells. This condition is characterised by a benign ovarian neoplasm, and abdomi...", "[2F32.0] Cystic teratoma\n Def: A condition of the ovary, caused by abnormal proliferation due to genetic mutations, abnormal growth or division of germ cells. This condition is characterised by a benign ovarian neoplasm, and abdomi...\n --PARENT--> [2F32] Benign neoplasm of ovary\n Def: A non-metastasizing neoplasm that arises from the ovary. Representative examples include serous cystadenoma, mucinous cystadenoma, clear cell adenofibroma, benign Brenner tumour, thecoma, and fibroma....\n --CHILD--> [2F32.2] Meigs' syndrome\n Def: Meigs' syndrome is classically defined as the triad of ascites, pleural effusion, and benign ovarian fibroma. A key feature found in patients with Meigs' syndrome is the resolution of symptoms after t...", "[2F00.Y] Other specified benign neoplasm of middle ear or respiratory system\n --PARENT--> [2F00] Benign neoplasm of middle ear or respiratory system\n --CHILD--> [2F00.0] Middle ear endocrine tumour", "[2F00.Y] Other specified benign neoplasm of middle ear or respiratory system\n --PARENT--> [2F00] Benign neoplasm of middle ear or respiratory system\n --CHILD--> [2F00.1] Recurrent respiratory papillomatosis\n Def: Recurrent respiratory papillomatosis is a rare respiratory disease characterised by the development of exophytic papillomas, affecting the mucosa of the upper aero-digestive tract (with a strong predi...", "[2A00.1Y] Other specified embryonal tumours of brain\n --PARENT--> [2A00.1] Embryonal tumours of brain\n --PARENT--> [2A00] Primary neoplasms of brain", "[2A00.1Y] Other specified embryonal tumours of brain\n --PARENT--> [2A00.1] Embryonal tumours of brain\n --PARENT--> [2A00] Primary neoplasms of brain" ]	2F32.0	Cystic teratoma	[ { "from_icd11": "QB97", "icd10_code": "Z5111", "icd10_title": "Encounter for antineoplastic chemotherapy" }, { "from_icd11": "QB97", "icd10_code": "Z5112", "icd10_title": "Encounter for antineoplastic immunotherapy" }, { "from_icd11": "QB97", "icd10_code": "Z511", "icd10_title": "Encounter for antineoplastic chemotherapy and immunotherapy" }, { "from_icd11": "QB97", "icd10_code": "Z51", "icd10_title": "Encounter for other aftercare and medical care" }, { "from_icd11": "QB9Y", "icd10_code": "Z5181", "icd10_title": "Encounter for therapeutic drug level monitoring" }, { "from_icd11": "QC48.Y", "icd10_code": "Z794", "icd10_title": "Long term (current) use of insulin" }, { "from_icd11": "QC48.Y", "icd10_code": "Z7902", "icd10_title": "Long term (current) use of antithrombotics/antiplatelets" }, { "from_icd11": "QC48.Y", "icd10_code": "Z7982", "icd10_title": "Long term (current) use of aspirin" }, { "from_icd11": "QC48.Y", "icd10_code": "Z7984", "icd10_title": "Long term (current) use of oral hypoglycemic drugs" }, { "from_icd11": "QC48.Y", "icd10_code": "Z79899", "icd10_title": "Other long term (current) drug therapy" } ]	Z5111	Encounter for antineoplastic chemotherapy
A midline hockey-stick incision curving to the left was used, with careful dissection in the midline raphe. There was no breach of the deep cervical dilated veins on the surgical exposure. A left suboccipital craniectomy was performed, with C1 hemilaminectomy, and a part of the left occipital condyle was drilled down to facilitate surgical access. After applying the retractors, flow through deep veins was confirmed with intra-op ultrasonography. A hockey-stick dural incision was made. The tumour was firm, extra-axial, with a good arachnoid plane and was debulked internally to minimise retraction on adjacent structure . The dural entry point of the left vertebral artery was identified and seen to be separate from the dural base of the tumour. The tumour was then completely removed, and the dural base coagulated, giving a Simpson Grade 2 resection. Dura was closed with dural substitute reinforcement and sealant glue. The cervical fascia was closed in layers, with no significant venous bleeding. Intraoperative neuromonitoring was used throughout the procedure, which showed no changes in motor-evoked potentials (MEPs), somatosensory-evoked potentials (SSEPs), corticobulbar motor-evoked potentials (coMEPs) of lower cranial nerves, brainstem auditory-evoked potentials (BAEPs) and laryngeal adductor reflex (LAR). Spinal accessory and hypoglossal nerves were visualised and protected throughout the surgery.	3.970703	0.954102	sec[1]/p[7]	en	0.999995	PMC9337779	https://doi.org/10.7759/cureus.26403	[ "dural", "evoked", "potentials", "tumour", "midline", "hockey", "stick", "incision", "used", "cervical" ]	[ { "code": "LA90.2Y", "title": "Other specified peripheral venous malformations" }, { "code": "NA07.5", "title": "Traumatic epidural haemorrhage" }, { "code": "1D03.2", "title": "Intraspinal extradural abscess" }, { "code": "NA07.6Z", "title": "Traumatic subdural haemorrhage, unspecified whether acute or chronic" }, { "code": "NA07.61", "title": "Chronic traumatic subdural haemorrhage" }, { "code": "MC21.Y", "title": "Other specified impairment of electrophysiological functions" }, { "code": "MB72", "title": "Results of function studies of the nervous system" }, { "code": "9C84.4", "title": "Gaze-evoked nystagmus" }, { "code": "DA95", "title": "Coeliac disease" }, { "code": "EK92", "title": "Histiocytoses of uncertain malignant potential" } ]	=== ICD-11 CODES FOUND === [LA90.2Y] Other specified peripheral venous malformations Also known as: Other specified peripheral venous malformations \| Dural sinus malformation \| Cranial dural arteriovenous malformations \| Cranial dural arteriovenous fistula [NA07.5] Traumatic epidural haemorrhage Also known as: Traumatic epidural haemorrhage \| extradural haemorrhage \| traumatic epidural haematoma \| traumatic extradural haemorrhage \| extradural brain haematoma [1D03.2] Intraspinal extradural abscess Also known as: Intraspinal extradural abscess \| extradural abscess of spinal cord \| extradural embolic abscess of spinal cord \| extradural embolic abscess of spinal cord, any part \| extradural abscess NOS [NA07.6Z] Traumatic subdural haemorrhage, unspecified whether acute or chronic Also known as: Traumatic subdural haemorrhage, unspecified whether acute or chronic \| Traumatic subdural haemorrhage \| subdural haemorrhage following injury \| traumatic subdural haematoma \| acute subdural haematoma NOS [NA07.61] Chronic traumatic subdural haemorrhage Also known as: Chronic traumatic subdural haemorrhage \| chronic subdural haematoma Includes: chronic subdural haematoma [MC21.Y] Other specified impairment of electrophysiological functions Also known as: Other specified impairment of electrophysiological functions \| Normal electrooculogram \| Normal EOG \| Moderate impairment of electrooculogram \| Moderate impairment of EOG [MB72] Results of function studies of the nervous system Also known as: Results of function studies of the nervous system \| Abnormal results of function studies of central nervous system \| abnormal central nervous system function studies \| Abnormal brain function studies \| Abnormal EEG - [electroencephalogram] [9C84.4] Gaze-evoked nystagmus Also known as: Gaze-evoked nystagmus \| Gaze-paretic nystagmus \| End-point nystagmus \| Rebound nystagmus \| Centripetal nystagmus [DA95] Coeliac disease Definition: Coeliac disease is a permanent intolerance to gluten proteins, present in wheat, rye, and barley. It is an autoimmune disorder, characterised by a chronic inflammatory state of the small intestinal mucosa and submucosa, which can impair digestion and absorption of nutrients, leading to malnutrition. Also known as: Coeliac disease \| Gluten-sensitive enteropathy \| Nontropical sprue \| coeliac rickets \| Gee disease Includes: Gluten-sensitive enteropathy \| Nontropical sprue \| Idiopathic steatorrhoea [EK92] Histiocytoses of uncertain malignant potential Definition: Disorders characterised by abnormal proliferation of dendritic cells and macrophages. The proliferation may or may not be clonal and the prognosis is unpredictable. Also known as: Histiocytoses of uncertain malignant potential \| Systemic non-Langerhans cell histiocytosis \| Faisalabad histiocytosis \| Sea-blue histiocytosis \| Sinus histiocytosis with massive lymphadenopathy === GRAPH WALKS === --- Walk 1 --- [LA90.2Y] Other specified peripheral venous malformations --PARENT--> [LA90.2] Peripheral venous malformations --RELATED_TO--> [?] Developmental venous malformations involving the skin Def: Certain genetically-determined syndromes presenting with venous anomalies in the skin... --- Walk 2 --- [LA90.2Y] Other specified peripheral venous malformations --PARENT--> [LA90.2] Peripheral venous malformations --RELATED_TO--> [?] Blue rubber bleb naevus syndrome Def: Blue rubber bleb nevus (BRBNS) is a rare vascular malformation disorder with cutaneous and visceral lesions frequently associated with serious, potentially fatal bleeding and anaemia. Multifocal venou... --- Walk 3 --- [NA07.5] Traumatic epidural haemorrhage --PARENT--> [NA07] Intracranial injury Def: Damage inflicted on the tissues of the brain as the direct or indirect result of an external force, with or without disruption of structural continuity.... --CHILD--> [NA07.1] Traumatic intracerebral haemorrhage --- Walk 4 --- [NA07.5] Traumatic epidural haemorrhage --RELATED_TO--> [?] Extradural or epidural haemorrhage due to birth injury Def: Haemorrhage in the plane between the skull bone and the periosteum on the inner surface of the skull from injury to the middle meningeal artery from birth trauma... --CHILD--> [?] Extradural haemorrhage due to birth injury --- Walk 5 --- [1D03.2] Intraspinal extradural abscess --PARENT--> [1D03] Infectious abscess of the central nervous system Def: A focal suppurative process of the brain parenchyma, the intracranial or spinal epidural or subdural space, and less commonly the spinal cord parenchyma. The suppurative process is most commonly assoc... --CHILD--> [1D03.0] Intraspinal intramedullary abscess --- Walk 6 --- [1D03.2] Intraspinal extradural abscess --PARENT--> [1D03] Infectious abscess of the central nervous system Def: A focal suppurative process of the brain parenchyma, the intracranial or spinal epidural or subdural space, and less commonly the spinal cord parenchyma. The suppurative process is most commonly assoc... --CHILD--> [1D03.0] Intraspinal intramedullary abscess	[ "[LA90.2Y] Other specified peripheral venous malformations\n --PARENT--> [LA90.2] Peripheral venous malformations\n --RELATED_TO--> [?] Developmental venous malformations involving the skin\n Def: Certain genetically-determined syndromes presenting with venous anomalies in the skin...", "[LA90.2Y] Other specified peripheral venous malformations\n --PARENT--> [LA90.2] Peripheral venous malformations\n --RELATED_TO--> [?] Blue rubber bleb naevus syndrome\n Def: Blue rubber bleb nevus (BRBNS) is a rare vascular malformation disorder with cutaneous and visceral lesions frequently associated with serious, potentially fatal bleeding and anaemia. Multifocal venou...", "[NA07.5] Traumatic epidural haemorrhage\n --PARENT--> [NA07] Intracranial injury\n Def: Damage inflicted on the tissues of the brain as the direct or indirect result of an external force, with or without disruption of structural continuity....\n --CHILD--> [NA07.1] Traumatic intracerebral haemorrhage", "[NA07.5] Traumatic epidural haemorrhage\n --RELATED_TO--> [?] Extradural or epidural haemorrhage due to birth injury\n Def: Haemorrhage in the plane between the skull bone and the periosteum on the inner surface of the skull from injury to the middle meningeal artery from birth trauma...\n --CHILD--> [?] Extradural haemorrhage due to birth injury", "[1D03.2] Intraspinal extradural abscess\n --PARENT--> [1D03] Infectious abscess of the central nervous system\n Def: A focal suppurative process of the brain parenchyma, the intracranial or spinal epidural or subdural space, and less commonly the spinal cord parenchyma. The suppurative process is most commonly assoc...\n --CHILD--> [1D03.0] Intraspinal intramedullary abscess", "[1D03.2] Intraspinal extradural abscess\n --PARENT--> [1D03] Infectious abscess of the central nervous system\n Def: A focal suppurative process of the brain parenchyma, the intracranial or spinal epidural or subdural space, and less commonly the spinal cord parenchyma. The suppurative process is most commonly assoc...\n --CHILD--> [1D03.0] Intraspinal intramedullary abscess" ]	LA90.2Y	Other specified peripheral venous malformations	[ { "from_icd11": "NA07.5", "icd10_code": "S064X9A", "icd10_title": "Epidural hemorrhage with loss of consciousness of unspecified duration, initial encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064X0A", "icd10_title": "Epidural hemorrhage without loss of consciousness, initial encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064X2A", "icd10_title": "Epidural hemorrhage with loss of consciousness of 31 minutes to 59 minutes, initial encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064X6A", "icd10_title": "Epidural hemorrhage with loss of consciousness greater than 24 hours without return to pre-existing conscious level with patient surviving, initial encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064X1A", "icd10_title": "Epidural hemorrhage with loss of consciousness of 30 minutes or less, initial encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064X7A", "icd10_title": "Epidural hemorrhage with loss of consciousness of any duration with death due to brain injury prior to regaining consciousness, initial encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064X9S", "icd10_title": "Epidural hemorrhage with loss of consciousness of unspecified duration, sequela" }, { "from_icd11": "NA07.5", "icd10_code": "S064X0S", "icd10_title": "Epidural hemorrhage without loss of consciousness, sequela" }, { "from_icd11": "NA07.5", "icd10_code": "S064X9D", "icd10_title": "Epidural hemorrhage with loss of consciousness of unspecified duration, subsequent encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064X5A", "icd10_title": "Epidural hemorrhage with loss of consciousness greater than 24 hours with return to pre-existing conscious level, initial encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064X8A", "icd10_title": "Epidural hemorrhage with loss of consciousness of any duration with death due to other causes prior to regaining consciousness, initial encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064X3A", "icd10_title": "Epidural hemorrhage with loss of consciousness of 1 hour to 5 hours 59 minutes, initial encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064X4A", "icd10_title": "Epidural hemorrhage with loss of consciousness of 6 hours to 24 hours, initial encounter" }, { "from_icd11": "NA07.5", "icd10_code": "S064", "icd10_title": "Epidural hemorrhage" }, { "from_icd11": "MB72", "icd10_code": "R29818", "icd10_title": "Other symptoms and signs involving the nervous system" } ]	S064X9A	Epidural hemorrhage with loss of consciousness of unspecified duration, initial encounter
A 53-year-old man with enlarged cervical lymph nodes was described by Yu Fujiwara et al. , and a biopsy revealed embryonal cancer in this case. After one month of treatment with the Bleomycin, Etoposide, and Cisplatin (BEP) regimen, the patient had developed skin lesions of DM . Yuki Otsuka et al. described a case of a 61-year-old woman who had invasive ductal breast cancer and had developed DM . Yuta Ito et al. described a case of an ovarian cancer patient, age 50, who acquired diabetes after undergoing hysterectomy, adnexectomy, and chemotherapy with Paclitaxel and Carboplatin (PTX + CBDCA) . They had hypothesised that cytokines such tumour necrosis factor (TNF)- may be crucial in the development of scleroderma/DM caused by taxanes. After receiving chemotherapy with Carboplatin and Capecitabine, a 76-year-old man with a recent diagnosis of metastatic gastric adenocarcinoma developed diabetes mellitus, according to a case study by Xiaolong et al. . A few of the many medications that have a higher degree of correlation with DM are etoposide, carboplatin, paclitaxel, bleomycin, cisplatin and cyclophosphamide. We attribute the development of DM to chemotherapy rather than the malignancy of Retinoblastoma because there is no evidence linking it to the development of DM. Our patient received etoposide and carboplatin for 13 cycles during which time she developed the hall cutaneous manifestations of DM.	3.994141	0.674805	sec[2]/p[4]	en	0.999997	PMC9620603	https://doi.org/10.1186/s12887-022-03704-5	[ "carboplatin", "cancer", "etoposide", "chemotherapy", "development", "bleomycin", "cisplatin", "diabetes", "paclitaxel", "that" ]	[ { "code": "2D4Z", "title": "Unspecified malignant neoplasms of unspecified sites" }, { "code": "2C0Z", "title": "Malignant neoplasms of intestine, unspecified" }, { "code": "2B5Z", "title": "Malignant mesenchymal neoplasm of unspecified type" }, { "code": "2E2Z", "title": "Malignant neoplasm metastasis, unspecified" }, { "code": "2D42", "title": "Malignant neoplasms of ill-defined sites" }, { "code": "QB97", "title": "Contact with health services for chemotherapy session for neoplasm" }, { "code": "QC05.Y", "title": "Other specified prophylactic measures" }, { "code": "QB9Y", "title": "Other specified contact with health services for nonsurgical interventions not involving devices" }, { "code": "3B64.1Y", "title": "Other specified acquired thrombocytopenia" }, { "code": "QC48.Y", "title": "Other specified personal history of medical treatment" } ]	=== ICD-11 CODES FOUND === [2D4Z] Unspecified malignant neoplasms of unspecified sites Also known as: Unspecified malignant neoplasms of unspecified sites \| malignancy of unspecified site \| malignancy unspecified primary site \| malignant growth of unspecified site \| malignant mass of unspecified site [2C0Z] Malignant neoplasms of intestine, unspecified Also known as: Malignant neoplasms of intestine, unspecified \| cancer of intestine \| malignant neoplasm of intestine NOS \| malignant tumour of intestine NOS \| intestinal cancer NOS [2B5Z] Malignant mesenchymal neoplasm of unspecified type Also known as: Malignant mesenchymal neoplasm of unspecified type \| calvarium cancer \| ethmoid bone cancer \| facial bone cancer \| frontal bone cancer [2E2Z] Malignant neoplasm metastasis, unspecified Also known as: Malignant neoplasm metastasis, unspecified \| secondary malignant neoplasm \| metastasis \| metastases \| disseminated metastases [2D42] Malignant neoplasms of ill-defined sites Definition: Malignant neoplasms of ill defined sites is used for cases where the documentation refers to a site that includes multiple organ systems and tissue types that should be coded separately. Also known as: Malignant neoplasms of ill-defined sites \| Malignant neoplasm of ill-defined site of head, face or neck \| Malignant neoplasm of nose NOS \| Primary malignant neoplasm of cheek \| malignant neoplasm of cheek NOS [QB97] Contact with health services for chemotherapy session for neoplasm Also known as: Contact with health services for chemotherapy session for neoplasm \| antineoplastic chemotherapy regimen \| cancer chemotherapy regimen \| maintenance chemotherapy for neoplasm \| neoplasm chemotherapy [QC05.Y] Other specified prophylactic measures Also known as: Other specified prophylactic measures \| Other prophylactic chemotherapy \| chemoprophylaxis \| prophylactic chemotherapy \| Systemic prophylactic chemotherapy [QB9Y] Other specified contact with health services for nonsurgical interventions not involving devices Also known as: Other specified contact with health services for nonsurgical interventions not involving devices \| Chemotherapy other than for neoplasm \| admission for chemotherapy administration other than for neoplasm \| chemotherapy regimen other than for neoplasm \| drug therapy other than for neoplasm [3B64.1Y] Other specified acquired thrombocytopenia Also known as: Other specified acquired thrombocytopenia \| Acquired thrombocytopenia specified as refractory \| Chemotherapy thrombocytopaenia \| Liver thrombocytopaenia [QC48.Y] Other specified personal history of medical treatment Also known as: Other specified personal history of medical treatment \| Personal history of contraception \| history of contraception \| Personal history of long-term use of medicaments other than anticoagulants \| personal history of long term current use of medicaments === GRAPH WALKS === --- Walk 1 --- [2D4Z] Unspecified malignant neoplasms of unspecified sites --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites --CHILD--> [2D42] Malignant neoplasms of ill-defined sites Def: Malignant neoplasms of ill defined sites is used for cases where the documentation refers to a site that includes multiple organ systems and tissue types that should be coded separately.... --- Walk 2 --- [2D4Z] Unspecified malignant neoplasms of unspecified sites --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites --EXCLUDES--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --- Walk 3 --- [2C0Z] Malignant neoplasms of intestine, unspecified --PARENT--> [?] Malignant neoplasms of intestine --EXCLUDES--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --- Walk 4 --- [2C0Z] Malignant neoplasms of intestine, unspecified --PARENT--> [?] Malignant neoplasms of intestine --CHILD--> [2B80] Malignant neoplasms of small intestine Def: A primary malignant neoplasm involving the small intestine.... --- Walk 5 --- [2B5Z] Malignant mesenchymal neoplasm of unspecified type --PARENT--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --EXCLUDES--> [?] Mesenchymal tumours of meninges --- Walk 6 --- [2B5Z] Malignant mesenchymal neoplasm of unspecified type --PARENT--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --EXCLUDES--> [?] Mesenchymal tumours of meninges	[ "[2D4Z] Unspecified malignant neoplasms of unspecified sites\n --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites\n --CHILD--> [2D42] Malignant neoplasms of ill-defined sites\n Def: Malignant neoplasms of ill defined sites is used for cases where the documentation refers to a site that includes multiple organ systems and tissue types that should be coded separately....", "[2D4Z] Unspecified malignant neoplasms of unspecified sites\n --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites\n --EXCLUDES--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...", "[2C0Z] Malignant neoplasms of intestine, unspecified\n --PARENT--> [?] Malignant neoplasms of intestine\n --EXCLUDES--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...", "[2C0Z] Malignant neoplasms of intestine, unspecified\n --PARENT--> [?] Malignant neoplasms of intestine\n --CHILD--> [2B80] Malignant neoplasms of small intestine\n Def: A primary malignant neoplasm involving the small intestine....", "[2B5Z] Malignant mesenchymal neoplasm of unspecified type\n --PARENT--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...\n --EXCLUDES--> [?] Mesenchymal tumours of meninges", "[2B5Z] Malignant mesenchymal neoplasm of unspecified type\n --PARENT--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...\n --EXCLUDES--> [?] Mesenchymal tumours of meninges" ]	2D4Z	Unspecified malignant neoplasms of unspecified sites	[ { "from_icd11": "2D4Z", "icd10_code": "C802", "icd10_title": "Malignant neoplasm associated with transplanted organ" }, { "from_icd11": "2D4Z", "icd10_code": "C7650", "icd10_title": "Malignant neoplasm of unspecified lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7642", "icd10_title": "Malignant neoplasm of left upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7640", "icd10_title": "Malignant neoplasm of unspecified upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7652", "icd10_title": "Malignant neoplasm of left lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7651", "icd10_title": "Malignant neoplasm of right lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7641", "icd10_title": "Malignant neoplasm of right upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C801", "icd10_title": "Malignant (primary) neoplasm, unspecified" }, { "from_icd11": "2D4Z", "icd10_code": "C768", "icd10_title": "Malignant neoplasm of other specified ill-defined sites" }, { "from_icd11": "2D4Z", "icd10_code": "C761", "icd10_title": "Malignant neoplasm of thorax" }, { "from_icd11": "2D4Z", "icd10_code": "C762", "icd10_title": "Malignant neoplasm of abdomen" }, { "from_icd11": "2D4Z", "icd10_code": "C763", "icd10_title": "Malignant neoplasm of pelvis" }, { "from_icd11": "2D4Z", "icd10_code": "C800", "icd10_title": "Disseminated malignant neoplasm, unspecified" }, { "from_icd11": "2D4Z", "icd10_code": "C76-C80", "icd10_title": "" }, { "from_icd11": "2D4Z", "icd10_code": "C76", "icd10_title": "Malignant neoplasm of other and ill-defined sites" } ]	C802	Malignant neoplasm associated with transplanted organ
An extensive anteromedial approach was applied. Resection margin of soft tissue was determined according to the MRI images. The PSG, fitting anatomically on the distal tibia, was firmly stabilized with K-wires to facilitate planned osteotomy . Then the tibia was elevated to expose posterior structures for en-bloc tumor resection. The tibial nerve and common peroneal nerve, being located outside the border of the tumor, were left intact. Three nutrient arteries and vena comitans were transected while the superficial veins were preserved. The tumor thrombus was removed en bloc with the popliteal vein. The length of the posterior tibial artery defect was measured and the great saphenous vein contralaterally located was harvested as a graft to rebuild the blood perfusion. The knee joint was reconstructed with a rotating-hinge modular system, followed by connection to the custom-made prosthesis. Afterwards, the plate and screws were inserted to strengthen the fixation at the ultra-small tibial stump. Extensor apparatus was restored by a double-surface mechanism. Medial gastrocnemius flap was transposed to wrap the proximal prosthesis. Soleus muscle was horizontally stretched and sutured with anterior tibial muscle fascia to cover the middle portion . Pulsatile lavage with saline solution was used to rinse the surgical area and the wound was closed in layers. Histological analysis showed an R0 resection.	3.923828	0.941895	sec[3]/p[0]	en	0.999997	PMC9195185	https://doi.org/10.3389/fsurg.2022.873272	[ "tibial", "resection", "tumor", "tibia", "bloc", "nerve", "located", "vein", "prosthesis", "muscle" ]	[ { "code": "LB9A.1", "title": "Tibial hemimelia" }, { "code": "FA31.Y", "title": "Other specified acquired deformities of limbs" }, { "code": "FB54.Y", "title": "Other specified enthesopathies of lower limb" }, { "code": "8C75", "title": "Distal myopathies" }, { "code": "8C11.4", "title": "Lesion of tibial nerve" }, { "code": "2F9Z", "title": "Neoplasms of unknown behaviour of unspecified site" }, { "code": "ME61", "title": "Subcutaneous swelling, mass or lump of uncertain or unspecified nature" }, { "code": "2E6Z", "title": "Carcinoma in situ of unspecified site" }, { "code": "2F91.1", "title": "Neoplasms of unknown behaviour of trachea, bronchus or lung" }, { "code": "2F92", "title": "Neoplasms of unknown behaviour of skin" } ]	=== ICD-11 CODES FOUND === [LB9A.1] Tibial hemimelia Definition: Tibial hemimelia is a rare congenital anomaly characterised by deficiency of the tibia with a relatively intact fibula. Also known as: Tibial hemimelia \| Longitudinal reduction defect of tibia \| agenesis of tibia \| congenital absence of tibia \| congenital absence of tibia with or without absence of some distal elements [FA31.Y] Other specified acquired deformities of limbs Also known as: Other specified acquired deformities of limbs \| Acquired deformity of forearm \| Deflection of radius \| Bowing of the radius \| Bowing of forearm [FB54.Y] Other specified enthesopathies of lower limb Also known as: Other specified enthesopathies of lower limb \| Anterior tibial syndrome \| Enthesopathy of hip region \| enthesopathy of hip NOS \| Enthesopathy of knee region Includes: Anterior tibial syndrome [8C75] Distal myopathies Definition: Distal myopathies are heterogeneous group of myopathies characterised clinically by progressive weakness and atrophy starting in distal muscles and progressing to proximal ones, and histologically by nonspecific myopathic features on muscle biopsy. Also known as: Distal myopathies \| Distal muscular dystrophy \| Distal myopathy with anterior tibial onset \| Markesbery-Griggs distal myopathy \| Tibial muscular dystrophy [8C11.4] Lesion of tibial nerve Also known as: Lesion of tibial nerve \| Lesion of medial popliteal nerve \| Lesion of sural nerve Excludes: Injury of tibial nerve at lower leg level [2F9Z] Neoplasms of unknown behaviour of unspecified site Also known as: Neoplasms of unknown behaviour of unspecified site \| neoplasia \| neoplasm growth NOS \| tumour of unspecified site \| tumourlet of unspecified site [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Definition: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature Also known as: Subcutaneous swelling, mass or lump of uncertain or unspecified nature \| localised swelling, mass or lump of skin and subcutaneous tissue \| localised subcutaneous nodules \| subcutaneous nodules \| superficial subcutaneous nodules Excludes: localized adiposity \| mass and lump: breast \| enlarged lymph nodes [2E6Z] Carcinoma in situ of unspecified site Also known as: Carcinoma in situ of unspecified site \| carcinoma in situ of unspecified site \| carcinoma in situ NOS \| carcinoma in situ \| in situ neoplasm [2F91.1] Neoplasms of unknown behaviour of trachea, bronchus or lung Also known as: Neoplasms of unknown behaviour of trachea, bronchus or lung \| trachea, bronchus or lung tumour NOS \| Intravascular bronchial alveolar tumour of unspecified site \| Bronchial adenoma of unknown behaviour of unspecified site \| Intravascular bronchial alveolar tumour unknown behaviour of unspecified site [2F92] Neoplasms of unknown behaviour of skin Also known as: Neoplasms of unknown behaviour of skin \| skin tumour NOS === GRAPH WALKS === --- Walk 1 --- [LB9A.1] Tibial hemimelia Def: Tibial hemimelia is a rare congenital anomaly characterised by deficiency of the tibia with a relatively intact fibula.... --PARENT--> [LB9A] Reduction defects of lower limb Def: Any condition caused by the failure of a lower limb to correctly develop during the antenatal period. These conditions are characterised by reduction in size or absence of the limb.... --CHILD--> [LB9A.0] Amelia of lower limb --- Walk 2 --- [LB9A.1] Tibial hemimelia Def: Tibial hemimelia is a rare congenital anomaly characterised by deficiency of the tibia with a relatively intact fibula.... --PARENT--> [LB9A] Reduction defects of lower limb Def: Any condition caused by the failure of a lower limb to correctly develop during the antenatal period. These conditions are characterised by reduction in size or absence of the limb.... --CHILD--> [LB9A.0] Amelia of lower limb --- Walk 3 --- [FA31.Y] Other specified acquired deformities of limbs --PARENT--> [FA31] Other acquired deformities of limbs --EXCLUDES--> [?] Acquired deformities of fingers or toes --- Walk 4 --- [FA31.Y] Other specified acquired deformities of limbs --PARENT--> [FA31] Other acquired deformities of limbs --PARENT--> [?] Certain specified joint disorders or deformities of limbs --- Walk 5 --- [FB54.Y] Other specified enthesopathies of lower limb --PARENT--> [FB54] Enthesopathies of lower limb Def: This is a group of disorders which refer to any abnormality of tendon and ligament insertion points of the leg. Abnormalities include inflammation and calcification.... --EXCLUDES--> [?] Bursitis related to use, overuse or pressure Def: This is a disorder of inflammation of one or more bursae (small sacs) of synovial fluid in the body which usually results in pain and is caused by repetitive use, overuse and pressure irritation.... --- Walk 6 --- [FB54.Y] Other specified enthesopathies of lower limb --PARENT--> [FB54] Enthesopathies of lower limb Def: This is a group of disorders which refer to any abnormality of tendon and ligament insertion points of the leg. Abnormalities include inflammation and calcification.... --CHILD--> [FB54.0] Iliac crest spur Def: This is a disorder characterised by bony exostosis at iliac muscle origins....	[ "[LB9A.1] Tibial hemimelia\n Def: Tibial hemimelia is a rare congenital anomaly characterised by deficiency of the tibia with a relatively intact fibula....\n --PARENT--> [LB9A] Reduction defects of lower limb\n Def: Any condition caused by the failure of a lower limb to correctly develop during the antenatal period. These conditions are characterised by reduction in size or absence of the limb....\n --CHILD--> [LB9A.0] Amelia of lower limb", "[LB9A.1] Tibial hemimelia\n Def: Tibial hemimelia is a rare congenital anomaly characterised by deficiency of the tibia with a relatively intact fibula....\n --PARENT--> [LB9A] Reduction defects of lower limb\n Def: Any condition caused by the failure of a lower limb to correctly develop during the antenatal period. These conditions are characterised by reduction in size or absence of the limb....\n --CHILD--> [LB9A.0] Amelia of lower limb", "[FA31.Y] Other specified acquired deformities of limbs\n --PARENT--> [FA31] Other acquired deformities of limbs\n --EXCLUDES--> [?] Acquired deformities of fingers or toes", "[FA31.Y] Other specified acquired deformities of limbs\n --PARENT--> [FA31] Other acquired deformities of limbs\n --PARENT--> [?] Certain specified joint disorders or deformities of limbs", "[FB54.Y] Other specified enthesopathies of lower limb\n --PARENT--> [FB54] Enthesopathies of lower limb\n Def: This is a group of disorders which refer to any abnormality of tendon and ligament insertion points of the leg. Abnormalities include inflammation and calcification....\n --EXCLUDES--> [?] Bursitis related to use, overuse or pressure\n Def: This is a disorder of inflammation of one or more bursae (small sacs) of synovial fluid in the body which usually results in pain and is caused by repetitive use, overuse and pressure irritation....", "[FB54.Y] Other specified enthesopathies of lower limb\n --PARENT--> [FB54] Enthesopathies of lower limb\n Def: This is a group of disorders which refer to any abnormality of tendon and ligament insertion points of the leg. Abnormalities include inflammation and calcification....\n --CHILD--> [FB54.0] Iliac crest spur\n Def: This is a disorder characterised by bony exostosis at iliac muscle origins...." ]	LB9A.1	Tibial hemimelia	[ { "from_icd11": "LB9A.1", "icd10_code": "Q7252", "icd10_title": "Longitudinal reduction defect of left tibia" }, { "from_icd11": "LB9A.1", "icd10_code": "Q725", "icd10_title": "Longitudinal reduction defect of tibia" }, { "from_icd11": "8C75", "icd10_code": "G718", "icd10_title": "Other primary disorders of muscles" }, { "from_icd11": "8C11.4", "icd10_code": "G574", "icd10_title": "Lesion of medial popliteal nerve" }, { "from_icd11": "2F9Z", "icd10_code": "D487", "icd10_title": "Neoplasm of uncertain behavior of other specified sites" }, { "from_icd11": "2F9Z", "icd10_code": "D482", "icd10_title": "Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system" }, { "from_icd11": "2F9Z", "icd10_code": "D37-D48", "icd10_title": "" }, { "from_icd11": "2F9Z", "icd10_code": "D377", "icd10_title": "" }, { "from_icd11": "2F9Z", "icd10_code": "D48", "icd10_title": "Neoplasm of uncertain behavior of other and unspecified sites" }, { "from_icd11": "2F9Z", "icd10_code": "D489", "icd10_title": "Neoplasm of uncertain behavior, unspecified" }, { "from_icd11": "ME61", "icd10_code": "R2240", "icd10_title": "Localized swelling, mass and lump, unspecified lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2232", "icd10_title": "Localized swelling, mass and lump, left upper limb" }, { "from_icd11": "ME61", "icd10_code": "R2242", "icd10_title": "Localized swelling, mass and lump, left lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2231", "icd10_title": "Localized swelling, mass and lump, right upper limb" }, { "from_icd11": "ME61", "icd10_code": "R2241", "icd10_title": "Localized swelling, mass and lump, right lower limb" } ]	Q7252	Longitudinal reduction defect of left tibia
A literature review of nummular headache cases by Dai et al. illustrates the diversity of the possible clinical presentations (Table 2 ), and the cases presented in this paper are no exception . With respect to Case 1 in the current report, the patient presented with an occipital midline region of pain, which is a rare presentation in itself when compared to the more common regions of pain found in nummular headaches as seen in Table 2 . The patient failed several therapeutic interventions with little to no relief. Eventually, the patient was amendable to taking a low dose of topiramate and managing the pain conservatively. It is unknown if reduction of pain was successfully achieved for the patient as he was lost to follow-up. In Case 2, the patient presented with a less common distribution of pain in the right temporal region, similar to what is seen in Table 2 . After not finding marked improvement in pain with medication, this patient opted to undergo conservative management, which incidentally allowed symptom resolution. In both scenarios, medication intervention somewhat improved patient comfort but did not bring complete resolution of symptoms. The value of these two clinical cases is that they not only add to the small collection of cases already reported but also emphasize the importance of familiarity and the ability to distinguish nummular headaches from other primary headache syndromes.	4.054688	0.84375	sec[2]/p[4]	en	0.999998	PMC9199569	https://doi.org/10.7759/cureus.25043	[ "pain", "cases", "nummular", "headache", "this", "region", "which", "common", "headaches", "medication" ]	[ { "code": "MG3Z", "title": "Pain, unspecified" }, { "code": "8E43.Z", "title": "Pain disorders, unspecified" }, { "code": "MG31.Z", "title": "Acute pain, unspecified" }, { "code": "MG30.Z", "title": "Chronic pain, unspecified" }, { "code": "FB56.2", "title": "Myalgia" }, { "code": "JB20.Z", "title": "Single spontaneous delivery, unspecified" }, { "code": "QA48.0", "title": "Care or examination immediately after delivery" }, { "code": "9A7Y", "title": "Other specified disorders of the cornea" }, { "code": "EA82", "title": "Nummular dermatitis" }, { "code": "8A83", "title": "Other primary headache disorder" } ]	=== ICD-11 CODES FOUND === [MG3Z] Pain, unspecified Also known as: Pain, unspecified \| pain observations \| pain NOS \| generalised pain \| generalised pain, NOS [8E43.Z] Pain disorders, unspecified Also known as: Pain disorders, unspecified \| Pain disorders [MG31.Z] Acute pain, unspecified Also known as: Acute pain, unspecified \| Acute pain [MG30.Z] Chronic pain, unspecified Also known as: Chronic pain, unspecified \| Chronic pain [FB56.2] Myalgia Definition: This is a disorder characterised by pain in a muscle or group of muscles. Also known as: Myalgia \| muscle ache \| muscle soreness \| muscular pain \| myalgic Excludes: Chronic primary musculoskeletal pain \| Chronic secondary musculoskeletal pain [JB20.Z] Single spontaneous delivery, unspecified Also known as: Single spontaneous delivery, unspecified \| Single spontaneous delivery \| spontaneous delivery NOS \| normal delivery NOS \| uncomplicated delivery [QA48.0] Care or examination immediately after delivery Also known as: Care or examination immediately after delivery \| care and observation in uncomplicated delivery cases \| postpartum care immediately after delivery \| postpartum examination immediately after delivery \| Postpartum care after hospital delivery Excludes: Complications predominantly related to the puerperium [9A7Y] Other specified disorders of the cornea Also known as: Other specified disorders of the cornea \| Secondary disorders of sclera or cornea \| Disorders of sclera and cornea in diseases classified elsewhere \| Secondary keratitis or keratoconjunctivitis \| Keratitis and keratoconjunctivitis in other diseases classified elsewhere [EA82] Nummular dermatitis Definition: Cutaneous eruption otherwise known as discoid eczema characterised by discoid or coin-shaped plaques of eczema. The lesions usually occur on the extensor surfaces of the extremities, but the face and trunk may also be involved. The cause is unknown. Also known as: Nummular dermatitis \| Discoid eczema \| Nummular eczema \| Nummular dermatitis, exudative type \| Discoid eczema, exudative type [8A83] Other primary headache disorder Definition: A group of clinically heterogeneous headache disorders, believed to be primary. Although largely unrelated, they fall into four categories: headaches associated with physical exertion; headaches attributed to direct physical but innocuous stimuli; epicranial headaches; and other miscellaneous primary headache disorders. Also known as: Other primary headache disorder \| Primary cough headache \| Primary exercise headache \| Primary headache associated with sexual activity \| Preorgasmic headache === GRAPH WALKS === --- Walk 1 --- [MG3Z] Pain, unspecified --PARENT--> [?] Pain --CHILD--> [MG30] Chronic pain Def: Pain is an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. Chronic pain is pain that persists or recurs for longer t... --- Walk 2 --- [MG3Z] Pain, unspecified --PARENT--> [?] Pain --EXCLUDES--> [?] Mastodynia Def: The symptom of breast pain. This symptom may be classified as cyclic or non-cyclical depending on the clinical patterns.... --- Walk 3 --- [8E43.Z] Pain disorders, unspecified --PARENT--> [8E43] Pain disorders --EXCLUDES--> [?] Chronic neuropathic pain Def: Chronic neuropathic pain is chronic pain caused by a lesion or disease of the somatosensory nervous system. The pain may be spontaneous or evoked, as an increased response to a painful stimulus (hyper... --- Walk 4 --- [8E43.Z] Pain disorders, unspecified --PARENT--> [8E43] Pain disorders --EXCLUDES--> [?] Chronic neuropathic pain Def: Chronic neuropathic pain is chronic pain caused by a lesion or disease of the somatosensory nervous system. The pain may be spontaneous or evoked, as an increased response to a painful stimulus (hyper... --- Walk 5 --- [MG31.Z] Acute pain, unspecified --PARENT--> [MG31] Acute pain Def: Pain with a duration of less than 3 months. This code should be used only when there is no further specification of site.... --PARENT--> [?] Pain --- Walk 6 --- [MG31.Z] Acute pain, unspecified --PARENT--> [MG31] Acute pain Def: Pain with a duration of less than 3 months. This code should be used only when there is no further specification of site.... --CHILD--> [MG31.1] Acute headache, not elsewhere classified	[ "[MG3Z] Pain, unspecified\n --PARENT--> [?] Pain\n --CHILD--> [MG30] Chronic pain\n Def: Pain is an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. Chronic pain is pain that persists or recurs for longer t...", "[MG3Z] Pain, unspecified\n --PARENT--> [?] Pain\n --EXCLUDES--> [?] Mastodynia\n Def: The symptom of breast pain. This symptom may be classified as cyclic or non-cyclical depending on the clinical patterns....", "[8E43.Z] Pain disorders, unspecified\n --PARENT--> [8E43] Pain disorders\n --EXCLUDES--> [?] Chronic neuropathic pain\n Def: Chronic neuropathic pain is chronic pain caused by a lesion or disease of the somatosensory nervous system. The pain may be spontaneous or evoked, as an increased response to a painful stimulus (hyper...", "[8E43.Z] Pain disorders, unspecified\n --PARENT--> [8E43] Pain disorders\n --EXCLUDES--> [?] Chronic neuropathic pain\n Def: Chronic neuropathic pain is chronic pain caused by a lesion or disease of the somatosensory nervous system. The pain may be spontaneous or evoked, as an increased response to a painful stimulus (hyper...", "[MG31.Z] Acute pain, unspecified\n --PARENT--> [MG31] Acute pain\n Def: Pain with a duration of less than 3 months.\n\nThis code should be used only when there is no further specification of site....\n --PARENT--> [?] Pain", "[MG31.Z] Acute pain, unspecified\n --PARENT--> [MG31] Acute pain\n Def: Pain with a duration of less than 3 months.\n\nThis code should be used only when there is no further specification of site....\n --CHILD--> [MG31.1] Acute headache, not elsewhere classified" ]	MG3Z	Pain, unspecified	[ { "from_icd11": "MG3Z", "icd10_code": "R52", "icd10_title": "Pain, unspecified" }, { "from_icd11": "MG3Z", "icd10_code": "R529", "icd10_title": "" }, { "from_icd11": "MG31.Z", "icd10_code": "R520", "icd10_title": "" }, { "from_icd11": "MG30.Z", "icd10_code": "R521", "icd10_title": "" }, { "from_icd11": "MG30.Z", "icd10_code": "R522", "icd10_title": "" }, { "from_icd11": "FB56.2", "icd10_code": "M7918", "icd10_title": "Myalgia, other site" }, { "from_icd11": "FB56.2", "icd10_code": "M7910", "icd10_title": "Myalgia, unspecified site" }, { "from_icd11": "FB56.2", "icd10_code": "M7912", "icd10_title": "Myalgia of auxiliary muscles, head and neck" }, { "from_icd11": "FB56.2", "icd10_code": "M791", "icd10_title": "Myalgia" }, { "from_icd11": "JB20.Z", "icd10_code": "O80", "icd10_title": "Encounter for full-term uncomplicated delivery" }, { "from_icd11": "JB20.Z", "icd10_code": "O808", "icd10_title": "" }, { "from_icd11": "JB20.Z", "icd10_code": "O809", "icd10_title": "" }, { "from_icd11": "QA48.0", "icd10_code": "Z390", "icd10_title": "Encounter for care and examination of mother immediately after delivery" }, { "from_icd11": "EA82", "icd10_code": "L300", "icd10_title": "Nummular dermatitis" }, { "from_icd11": "8A83", "icd10_code": "G44209", "icd10_title": "Tension-type headache, unspecified, not intractable" } ]	R52	Pain, unspecified
A 54-year-old male with a history significant for chronic alcoholism, hypertension, anxiety, and depression presented to the headache clinic with complaints of daily headaches for the past three months, associated with photophobia, phonophobia, and nausea. He described a constant pressure and sharp-shooting pain localized to his left head and face, more specifically in the frontal and temporal regions. At the time of initial presentation to his primary physician it was unclear if he was suffering from migraine without aura or an isolated trigeminal neuralgia, as predominant V1 involvement is atypical in trigeminal neuralgia and was therefore started on gabapentin. He initially found relief with gabapentin but this soon lost efficacy. Eventually he was formerly diagnosed by a neurologist with trigeminal neuralgia and carbamazepine as well as baclofen were added to his regimen. Ultimately he was requiring increasing doses of carbamazepine due to breakthrough pain and ultimately he developed severe hyponatremia. The severity of his discomfort had significantly reduced his quality of his life, decreasing his ability to sleep, his ability to open his mouth causing him to stop eating and lose weight, and causing him considerable mental affliction consistent with signs of depression. Medication failure and quality of life reduction were an indication at this time for a trigeminal nerve glycerol rhizotomy.	3.878906	0.981445	sec[1]/p[6]	en	0.999997	PMC9246451	https://doi.org/10.7759/cureus.25538	[ "trigeminal", "neuralgia", "depression", "pain", "time", "gabapentin", "this", "carbamazepine", "ultimately", "quality" ]	[ { "code": "8B82.Z", "title": "Disorders of trigeminal nerve, unspecified" }, { "code": "ED30.0", "title": "Neuropathic skin ulceration" }, { "code": "NA04.4", "title": "Injury of trigeminal nerve" }, { "code": "8A82", "title": "Trigeminal autonomic cephalalgias" }, { "code": "2A02.3&XA72G0", "title": "Benign neoplasm of trigeminal nerve" }, { "code": "MG30.5Z", "title": "Chronic neuropathic pain, unspecified" }, { "code": "8A85", "title": "Painful cranial neuropathies or other facial pains" }, { "code": "AB70.2", "title": "Otalgia" }, { "code": "8B82.0", "title": "Trigeminal neuralgia" }, { "code": "ME84.3", "title": "Sciatica" } ]	=== ICD-11 CODES FOUND === [8B82.Z] Disorders of trigeminal nerve, unspecified Also known as: Disorders of trigeminal nerve, unspecified \| Disorders of trigeminal nerve \| Disorders of 5th cranial nerve \| disorders of the fifth cranial nerve \| Gasserian ganglion lesion [ED30.0] Neuropathic skin ulceration Definition: Ulceration of the skin resulting from impairment of pain sensation due to sensory nerve dysfunction. Also known as: Neuropathic skin ulceration \| Neuropathic ulcer \| Trigeminal trophic syndrome \| Neuropathic ulcer of lower limb Includes: Neuropathic ulcer [NA04.4] Injury of trigeminal nerve Also known as: Injury of trigeminal nerve \| injury of fifth cranial nerve \| trigeminal (5th) nerve injury \| injury of n.trigeminus \| Injury of trigeminal ganglion [8A82] Trigeminal autonomic cephalalgias Definition: A group of related primary headache disorders essentially characterised by unilateral headache and trigeminal autonomic activation. In most but not all of these disorders, the headache is short-lasting and very frequently recurring, but sometimes remitting for long periods. Also known as: Trigeminal autonomic cephalalgias \| Cluster headache \| Horton headache \| Episodic cluster headache \| Chronic cluster headache [MG30.5Z] Chronic neuropathic pain, unspecified Also known as: Chronic neuropathic pain, unspecified \| Chronic neuropathic pain \| anaesthesia dolorosa \| neuralgia \| chronic neurogenic pain (deprecated) [8A85] Painful cranial neuropathies or other facial pains Definition: A group of disorders characterised by head and/or facial pain, presenting variably as a neuralgia or as pain of neuropathic or central origin. Also known as: Painful cranial neuropathies or other facial pains \| Combined hyperactive dysfunction syndrome of the cranial nerves \| Supraorbital neuralgia \| Occipital neuralgia \| Tolosa-Hunt syndrome [AB70.2] Otalgia Definition: Pain in one or both ears. Also known as: Otalgia \| ear ache \| earache symptom \| pain in ear \| ear neuralgia Excludes: Chronic primary orofacial pain \| Chronic secondary headache or orofacial pain [8B82.0] Trigeminal neuralgia Definition: Trigeminal neuralgia is a manifestation of orofacial neuropathic pain restricted to one or more divisions of the trigeminal nerve. The pain is recurrent, abrupt in onset and termination, triggered by innocuous stimuli and typically compared to an electric shock or described as shooting or stabbing. Some patients experience continuous pain between these painful paroxysms. Also known as: Trigeminal neuralgia \| Tic douloureux \| Neuralgia of the fifth cranial nerve \| Neuralgia of 5th cranial nerve \| infraorbital neuralgia [ME84.3] Sciatica Also known as: Sciatica \| ischialgia \| neuralgia or neuritis of sciatic nerve \| sciatic neuralgia \| neuritis sciatic Excludes: Degenerative condition of spine \| Lesion of sciatic nerve \| Lumbago with sciatica === GRAPH WALKS === --- Walk 1 --- [8B82.Z] Disorders of trigeminal nerve, unspecified --PARENT--> [8B82] Disorders of trigeminal nerve Def: The trigeminal nerve is a mixed nerve with three divisions, ophthalmic, maxillary and mandibular divisions, that provides sensory innervation to the face and mucous membrane of the oral and nasal cavi... --CHILD--> [8B82.0] Trigeminal neuralgia Def: Trigeminal neuralgia is a manifestation of orofacial neuropathic pain restricted to one or more divisions of the trigeminal nerve. The pain is recurrent, abrupt in onset and termination, triggered by ... --- Walk 2 --- [8B82.Z] Disorders of trigeminal nerve, unspecified --PARENT--> [8B82] Disorders of trigeminal nerve Def: The trigeminal nerve is a mixed nerve with three divisions, ophthalmic, maxillary and mandibular divisions, that provides sensory innervation to the face and mucous membrane of the oral and nasal cavi... --RELATED_TO--> [?] Atypical facial pain Def: This is a chronic pain of the face, which does not meet other diagnostic criteria.... --- Walk 3 --- [ED30.0] Neuropathic skin ulceration Def: Ulceration of the skin resulting from impairment of pain sensation due to sensory nerve dysfunction.... --PARENT--> [ED30] Neuropathic skin damage Def: Skin changes attributable entirely or in part to sensory or autonomic nerve damage.... --CHILD--> [ED30.0] Neuropathic skin ulceration Def: Ulceration of the skin resulting from impairment of pain sensation due to sensory nerve dysfunction.... --- Walk 4 --- [ED30.0] Neuropathic skin ulceration Def: Ulceration of the skin resulting from impairment of pain sensation due to sensory nerve dysfunction.... --PARENT--> [ED30] Neuropathic skin damage Def: Skin changes attributable entirely or in part to sensory or autonomic nerve damage.... --CHILD--> [ED30.0] Neuropathic skin ulceration Def: Ulceration of the skin resulting from impairment of pain sensation due to sensory nerve dysfunction.... --- Walk 5 --- [NA04.4] Injury of trigeminal nerve --PARENT--> [NA04] Injury of cranial nerves --CHILD--> [NA04.0] Injury of olfactory nerve --- Walk 6 --- [NA04.4] Injury of trigeminal nerve --PARENT--> [NA04] Injury of cranial nerves --CHILD--> [NA04.2] Injury of oculomotor nerve	[ "[8B82.Z] Disorders of trigeminal nerve, unspecified\n --PARENT--> [8B82] Disorders of trigeminal nerve\n Def: The trigeminal nerve is a mixed nerve with three divisions, ophthalmic, maxillary and mandibular divisions, that provides sensory innervation to the face and mucous membrane of the oral and nasal cavi...\n --CHILD--> [8B82.0] Trigeminal neuralgia\n Def: Trigeminal neuralgia is a manifestation of orofacial neuropathic pain restricted to one or more divisions of the trigeminal nerve. The pain is recurrent, abrupt in onset and termination, triggered by ...", "[8B82.Z] Disorders of trigeminal nerve, unspecified\n --PARENT--> [8B82] Disorders of trigeminal nerve\n Def: The trigeminal nerve is a mixed nerve with three divisions, ophthalmic, maxillary and mandibular divisions, that provides sensory innervation to the face and mucous membrane of the oral and nasal cavi...\n --RELATED_TO--> [?] Atypical facial pain\n Def: This is a chronic pain of the face, which does not meet other diagnostic criteria....", "[ED30.0] Neuropathic skin ulceration\n Def: Ulceration of the skin resulting from impairment of pain sensation due to sensory nerve dysfunction....\n --PARENT--> [ED30] Neuropathic skin damage\n Def: Skin changes attributable entirely or in part to sensory or autonomic nerve damage....\n --CHILD--> [ED30.0] Neuropathic skin ulceration\n Def: Ulceration of the skin resulting from impairment of pain sensation due to sensory nerve dysfunction....", "[ED30.0] Neuropathic skin ulceration\n Def: Ulceration of the skin resulting from impairment of pain sensation due to sensory nerve dysfunction....\n --PARENT--> [ED30] Neuropathic skin damage\n Def: Skin changes attributable entirely or in part to sensory or autonomic nerve damage....\n --CHILD--> [ED30.0] Neuropathic skin ulceration\n Def: Ulceration of the skin resulting from impairment of pain sensation due to sensory nerve dysfunction....", "[NA04.4] Injury of trigeminal nerve\n --PARENT--> [NA04] Injury of cranial nerves\n --CHILD--> [NA04.0] Injury of olfactory nerve", "[NA04.4] Injury of trigeminal nerve\n --PARENT--> [NA04] Injury of cranial nerves\n --CHILD--> [NA04.2] Injury of oculomotor nerve" ]	8B82.Z	Disorders of trigeminal nerve, unspecified	[ { "from_icd11": "8B82.Z", "icd10_code": "G508", "icd10_title": "Other disorders of trigeminal nerve" }, { "from_icd11": "8B82.Z", "icd10_code": "G509", "icd10_title": "Disorder of trigeminal nerve, unspecified" }, { "from_icd11": "8B82.Z", "icd10_code": "G50", "icd10_title": "Disorders of trigeminal nerve" }, { "from_icd11": "ED30.0", "icd10_code": "L988", "icd10_title": "Other specified disorders of the skin and subcutaneous tissue" }, { "from_icd11": "NA04.4", "icd10_code": "S0430XA", "icd10_title": "Injury of trigeminal nerve, unspecified side, initial encounter" }, { "from_icd11": "NA04.4", "icd10_code": "S043", "icd10_title": "Injury of trigeminal nerve" }, { "from_icd11": "8A82", "icd10_code": "G441", "icd10_title": "Vascular headache, not elsewhere classified" }, { "from_icd11": "8A85", "icd10_code": "G501", "icd10_title": "Atypical facial pain" }, { "from_icd11": "AB70.2", "icd10_code": "H9209", "icd10_title": "Otalgia, unspecified ear" }, { "from_icd11": "AB70.2", "icd10_code": "H9203", "icd10_title": "Otalgia, bilateral" }, { "from_icd11": "AB70.2", "icd10_code": "H920", "icd10_title": "Otalgia" }, { "from_icd11": "8B82.0", "icd10_code": "G500", "icd10_title": "Trigeminal neuralgia" }, { "from_icd11": "ME84.3", "icd10_code": "M5430", "icd10_title": "Sciatica, unspecified side" }, { "from_icd11": "ME84.3", "icd10_code": "M5431", "icd10_title": "Sciatica, right side" }, { "from_icd11": "ME84.3", "icd10_code": "M5432", "icd10_title": "Sciatica, left side" } ]	G508	Other disorders of trigeminal nerve
Owing to the rapid progression of her respiratory failure, the patient received combination therapy including four courses of MPT (30 mg/kg/day for 3 days per course) followed by oral prednisolone (PSL; 1 mg/kg/day) and intravenous CyA (starting with 3 mg/kg/day and adjusted to maintain trough levels at 150–200 ng/mL), two courses of IVCY (500 mg/m 2 /dose at a 1-month interval), and IVIG . She also received trimethoprim–sulfadiazine as prophylaxis for opportunistic infections. Her respiratory condition deteriorated further, and she was placed on a ventilator support on day 11 of hospitalization; the following settings were used: mean airway pressure (MAP), 12 cmH 2 O; peak inspiratory pressure (PIP), 20 cmH 2 O;positive end-expiratory pressure (PEEP), 6 cmH 2 O; and FiO 2 , 0.8 (oxygen index: 8.0, PaO 2 /FiO 2 : 150). Fig. 2 Clinical course and treatment. Clinical course and treatment of the patient. MPT, methylprednisolone pulse therapy; PSL, prednisolone; Lipo-Dex, liposteroid dexamethasone; IVCY, intravenous cyclophosphamide; CyA, cyclosporine A; Tac, tacrolimus; MMF, mycophenolate mofetil; IVIG, intravenous immunoglobulin; PE, plasma exchange; RTX, rituximab; HFNC, High-flow nasal cannula; CMV, conventional mechanical ventilation; VV-ECMO, veno-venous extracorporeal membrane oxygenation; KL–6, Krebs von den Lungen-6; MDA5, melanoma differentiation-association gene 5; P/F ratio, PaO2/FiO2 ratio	3.951172	0.958984	sec[1]/p[2]	en	0.999998	PMC9351133	https://doi.org/10.1186/s12969-022-00723-5	[ "course", "intravenous", "pressure", "respiratory", "courses", "prednisolone", "ivcy", "ivig", "owing", "rapid" ]	[ { "code": "LA8Y", "title": "Other specified structural developmental anomaly of heart or great vessels" }, { "code": "8B10.Y", "title": "Other specified transient ischaemic attack" }, { "code": "6A80", "title": "Symptomatic and course presentations for mood episodes in mood disorders" }, { "code": "LA8C.1", "title": "Anomalous aortic origin or course of coronary artery" }, { "code": "8B22.Y", "title": "Other specified cerebrovascular disease" }, { "code": "QE11.Z", "title": "Hazardous drug use, unspecified" }, { "code": "PK91.16", "title": "Cardiovascular devices associated with injury or harm: peripheral venous catheter" }, { "code": "QE11.3", "title": "Hazardous use of cocaine" }, { "code": "JA61.5", "title": "Cerebral venous thrombosis in pregnancy" }, { "code": "8B22.1", "title": "Cerebral venous thrombosis" } ]	=== ICD-11 CODES FOUND === [LA8Y] Other specified structural developmental anomaly of heart or great vessels Also known as: Other specified structural developmental anomaly of heart or great vessels \| Congenital anomaly of position or spatial relationships of thoraco-abdominal organs \| Usual atrial arrangement \| atrial situs solitus \| Abnormal atrial arrangement [8B10.Y] Other specified transient ischaemic attack Also known as: Other specified transient ischaemic attack \| Vertebrobasilar artery syndrome \| vertebrobasilar arterial insufficiency \| vertebrobasilar insufficiency \| vertebro-basilar artery syndrome, course of resolution unspecified [6A80] Symptomatic and course presentations for mood episodes in mood disorders Definition: These categories may be applied to describe the presentation and characteristics of mood episodes in the context of single episode depressive disorder, recurrent depressive disorder, bipolar type I disorder, or bipolar type II disorder. These categories indicate the presence of specific, important features of the clinical presentation or of the course, onset, and pattern of mood episodes. These categories are not mutually exclusive, and as many may be added as apply. Also known as: Symptomatic and course presentations for mood episodes in mood disorders [LA8C.1] Anomalous aortic origin or course of coronary artery Definition: A congenital cardiovascular malformation in which the origin and/or course of a coronary artery is abnormal. This is where coronary "anomalies" in the presence of discordant ventriculo-arterial connections should be coded. Also known as: Anomalous aortic origin or course of coronary artery \| Anomalous aortic origin of coronary artery with ventriculo-arterial concordance \| Anomalous aortic origin of coronary artery \| AAOCA - [Anomalous aortic origin of coronary artery] \| Right coronary artery from left aortic sinus with ventriculo-arterial concordance [8B22.Y] Other specified cerebrovascular disease Also known as: Other specified cerebrovascular disease \| Posterior reversible encephalopathy \| Multiple or bilateral precerebral artery syndromes \| multiple or bilateral precerebral artery syndromes, course of resolution unspecified \| precerebral artery insufficiency NOS [QE11.Z] Hazardous drug use, unspecified Also known as: Hazardous drug use, unspecified \| Hazardous drug use \| chronic drug use NOS \| chronic IV substance use \| drug use nos [PK91.16] Cardiovascular devices associated with injury or harm: peripheral venous catheter Also known as: Cardiovascular devices associated with injury or harm: peripheral venous catheter \| complication of intravenous line \| IV - [intravenous] line complication Excludes: Circumstances associated with a surgical or other medical device influencing the episode of care without injury or harm [QE11.3] Hazardous use of cocaine Definition: A pattern of cocaine use that appreciably increases the risk of harmful physical or mental health consequences to the user or to others to an extent that warrants attention and advice from health professionals. The increased risk may be from the frequency of cocaine use, from the amount used on a given occasion, from risky behaviours associated with cocaine use or the context of use, from a harmful route of administration, or from a combination of these. The risk may be related to short-term eff Also known as: Hazardous use of cocaine \| cocaine use \| intravenous cocaine use \| Hazardous use of crack cocaine \| crack cocaine use Excludes: Disorders due to use of cocaine [JA61.5] Cerebral venous thrombosis in pregnancy Also known as: Cerebral venous thrombosis in pregnancy \| Cerebrovenous sinus thrombosis in pregnancy \| cerebral venous thrombosis in pregnancy, unspecified trimester \| intracranial venous sinus thrombosis of pregnancy Includes: Cerebrovenous sinus thrombosis in pregnancy [8B22.1] Cerebral venous thrombosis Definition: Thrombosis (blood clot) of the cerebral venous sinuses, which drain blood from brain Also known as: Cerebral venous thrombosis \| nonpyogenic thrombosis of intracranial venous system \| nonpyogenic thrombophlebitis of intracranial venous sinus \| nonpyogenic thrombosis of intracranial venous sinus \| Nonpyogenic thrombosis of cerebral vein Excludes: Cerebral ischaemic stroke \| Cerebral venous thrombosis in the puerperium === GRAPH WALKS === --- Walk 1 --- [LA8Y] Other specified structural developmental anomaly of heart or great vessels --PARENT--> [?] Structural developmental anomaly of heart or great vessels Def: A congenital malformation of the heart and/or great vessels or an acquired abnormality unique to the congenitally malformed heart.... --RELATED_TO--> [?] Congenital great vessel related acquired abnormality Def: Any postnatal pathological change in form or function of the heart and/or great vessels consequent to the presence of congenital cardiovascular disease.... --- Walk 2 --- [LA8Y] Other specified structural developmental anomaly of heart or great vessels --PARENT--> [?] Structural developmental anomaly of heart or great vessels Def: A congenital malformation of the heart and/or great vessels or an acquired abnormality unique to the congenitally malformed heart.... --RELATED_TO--> [?] Congenital great vessel related acquired abnormality Def: Any postnatal pathological change in form or function of the heart and/or great vessels consequent to the presence of congenital cardiovascular disease.... --- Walk 3 --- [8B10.Y] Other specified transient ischaemic attack --PARENT--> [8B10] Transient ischaemic attack Def: Transient episode of focal neurological dysfunction caused by focal brain ischemia without acute infarction in the clinically relevant area of the brain or transient monocular visual loss due to retin... --EXCLUDES--> [?] Transient global amnesia Def: A time-limited episode (lasting up to two days) of short-term memory loss without other signs or symptoms of neurological impairment.... --- Walk 4 --- [8B10.Y] Other specified transient ischaemic attack --PARENT--> [8B10] Transient ischaemic attack Def: Transient episode of focal neurological dysfunction caused by focal brain ischemia without acute infarction in the clinically relevant area of the brain or transient monocular visual loss due to retin... --CHILD--> [8B10.Z] Transient ischaemic attack, unspecified --- Walk 5 --- [6A80] Symptomatic and course presentations for mood episodes in mood disorders Def: These categories may be applied to describe the presentation and characteristics of mood episodes in the context of single episode depressive disorder, recurrent depressive disorder, bipolar type I di... --CHILD--> [6A80.2] Current depressive episode persistent Def: The diagnostic requirements for a depressive episode are currently met and have been met continuously for at least the past 2 years.... --PARENT--> [6A80] Symptomatic and course presentations for mood episodes in mood disorders Def: These categories may be applied to describe the presentation and characteristics of mood episodes in the context of single episode depressive disorder, recurrent depressive disorder, bipolar type I di... --- Walk 6 --- [6A80] Symptomatic and course presentations for mood episodes in mood disorders Def: These categories may be applied to describe the presentation and characteristics of mood episodes in the context of single episode depressive disorder, recurrent depressive disorder, bipolar type I di... --RELATED_TO--> [?] Mental or behavioural disorders associated with pregnancy, childbirth or the puerperium, with psychotic symptoms Def: A syndrome associated with pregnancy or the puerperium (commencing within about 6 weeks after delivery) that involves significant mental and behavioural features, including delusions, hallucinations, ... --PARENT--> [?] Symptomatic and course presentations for mood episodes in mood disorders Def: These categories may be applied to describe the presentation and characteristics of mood episodes in the context of single episode depressive disorder, recurrent depressive disorder, bipolar type I di...	[ "[LA8Y] Other specified structural developmental anomaly of heart or great vessels\n --PARENT--> [?] Structural developmental anomaly of heart or great vessels\n Def: A congenital malformation of the heart and/or great vessels or an acquired abnormality unique to the congenitally malformed heart....\n --RELATED_TO--> [?] Congenital great vessel related acquired abnormality\n Def: Any postnatal pathological change in form or function of the heart and/or great vessels consequent to the presence of congenital cardiovascular disease....", "[LA8Y] Other specified structural developmental anomaly of heart or great vessels\n --PARENT--> [?] Structural developmental anomaly of heart or great vessels\n Def: A congenital malformation of the heart and/or great vessels or an acquired abnormality unique to the congenitally malformed heart....\n --RELATED_TO--> [?] Congenital great vessel related acquired abnormality\n Def: Any postnatal pathological change in form or function of the heart and/or great vessels consequent to the presence of congenital cardiovascular disease....", "[8B10.Y] Other specified transient ischaemic attack\n --PARENT--> [8B10] Transient ischaemic attack\n Def: Transient episode of focal neurological dysfunction caused by focal brain ischemia without acute infarction in the clinically relevant area of the brain or transient monocular visual loss due to retin...\n --EXCLUDES--> [?] Transient global amnesia\n Def: A time-limited episode (lasting up to two days) of short-term memory loss without other signs or symptoms of neurological impairment....", "[8B10.Y] Other specified transient ischaemic attack\n --PARENT--> [8B10] Transient ischaemic attack\n Def: Transient episode of focal neurological dysfunction caused by focal brain ischemia without acute infarction in the clinically relevant area of the brain or transient monocular visual loss due to retin...\n --CHILD--> [8B10.Z] Transient ischaemic attack, unspecified", "[6A80] Symptomatic and course presentations for mood episodes in mood disorders\n Def: These categories may be applied to describe the presentation and characteristics of mood episodes in the context of single episode depressive disorder, recurrent depressive disorder, bipolar type I di...\n --CHILD--> [6A80.2] Current depressive episode persistent\n Def: The diagnostic requirements for a depressive episode are currently met and have been met continuously for at least the past 2 years....\n --PARENT--> [6A80] Symptomatic and course presentations for mood episodes in mood disorders\n Def: These categories may be applied to describe the presentation and characteristics of mood episodes in the context of single episode depressive disorder, recurrent depressive disorder, bipolar type I di...", "[6A80] Symptomatic and course presentations for mood episodes in mood disorders\n Def: These categories may be applied to describe the presentation and characteristics of mood episodes in the context of single episode depressive disorder, recurrent depressive disorder, bipolar type I di...\n --RELATED_TO--> [?] Mental or behavioural disorders associated with pregnancy, childbirth or the puerperium, with psychotic symptoms\n Def: A syndrome associated with pregnancy or the puerperium (commencing within about 6 weeks after delivery) that involves significant mental and behavioural features, including delusions, hallucinations, ...\n --PARENT--> [?] Symptomatic and course presentations for mood episodes in mood disorders\n Def: These categories may be applied to describe the presentation and characteristics of mood episodes in the context of single episode depressive disorder, recurrent depressive disorder, bipolar type I di..." ]	LA8Y	Other specified structural developmental anomaly of heart or great vessels	[ { "from_icd11": "LA8Y", "icd10_code": "Q248 ", "icd10_title": "" }, { "from_icd11": "QE11.Z", "icd10_code": "Z722", "icd10_title": "" }, { "from_icd11": "PK91.16", "icd10_code": "T8242XA", "icd10_title": "Displacement of vascular dialysis catheter, initial encounter" }, { "from_icd11": "PK91.16", "icd10_code": "T8249XD", "icd10_title": "Other complication of vascular dialysis catheter, subsequent encounter" }, { "from_icd11": "PK91.16", "icd10_code": "T8243XA", "icd10_title": "Leakage of vascular dialysis catheter, initial encounter" }, { "from_icd11": "PK91.16", "icd10_code": "T824", "icd10_title": "Mechanical complication of vascular dialysis catheter" }, { "from_icd11": "JA61.5", "icd10_code": "O2251", "icd10_title": "Cerebral venous thrombosis in pregnancy, first trimester" }, { "from_icd11": "JA61.5", "icd10_code": "O2252", "icd10_title": "Cerebral venous thrombosis in pregnancy, second trimester" }, { "from_icd11": "JA61.5", "icd10_code": "O2253", "icd10_title": "Cerebral venous thrombosis in pregnancy, third trimester" }, { "from_icd11": "JA61.5", "icd10_code": "O225", "icd10_title": "Cerebral venous thrombosis in pregnancy" }, { "from_icd11": "8B22.1", "icd10_code": "G08", "icd10_title": "Intracranial and intraspinal phlebitis and thrombophlebitis" }, { "from_icd11": "8B22.1", "icd10_code": "I676", "icd10_title": "Nonpyogenic thrombosis of intracranial venous system" }, { "from_icd11": "8B22.1", "icd10_code": "I636", "icd10_title": "Cerebral infarction due to cerebral venous thrombosis, nonpyogenic" } ]	Q248
Patient 3 was a 7‐year‐old boy, who was diagnosed with AD in early childhood, and was admitted to hospital due to severe exacerbation of his skin disease. Over the years, he had been treated with emollients and topical corticosteroids with mild to moderate improvement. At the age of 6 years, he had developed a pruritic linear lesion over his left thigh, leg and ankle, which was prominent during exacerbation of the atopic lesions and responded partially to topical treatment for AD. Physical examination revealed multiple eczematous plaques on the child's face, thorax and extremities, and on his left thigh, leg and ankle there was a linear lesion along the lines of Blaschko, composed of erythematous papules and plaques with an impressive rope‐like lichenification . Histology from the linear lesion demonstrated irregular acanthosis, packed hyperkeratosis and parakeratosis, marked spongiosis in the Malpighian layer, and perivascular and interstitial infiltrates composed of mononuclear cells and a few eosinophils in the upper dermal layer . Taken together, the clinical and pathological findings also pointed to the diagnosis of superimposed Type 2 segmental AD. The child was initially treated with coal tar 5% ointment and broad‐spectrum ultraviolet (UV)B phototherapy. After remission was achieved, he continued ambulatory phototherapy with narrowband UVB in combination with topical steroids and emollients.	4.054688	0.97998	sec[0]/p[2]	en	0.999996	35340038	https://doi.org/10.1111/ced.15196	[ "topical", "linear", "lesion", "exacerbation", "over", "treated", "emollients", "thigh", "ankle", "plaques" ]	[ { "code": "ED6Y", "title": "Other specified disorders of skin pigmentation" }, { "code": "NE60", "title": "Harmful effects of drugs, medicaments or biological substances, not elsewhere classified" }, { "code": "EK12", "title": "Allergic contact sensitisation" }, { "code": "PL00", "title": "Drugs, medicaments or biological substances associated with injury or harm in therapeutic use" }, { "code": "EK00.C", "title": "Allergic contact dermatitis due to topical medicaments" }, { "code": "EB61.1", "title": "Linear morphoea" }, { "code": "EB42", "title": "Linear IgA bullous dermatosis" }, { "code": "LC00.Y", "title": "Other specified keratinocytic epidermal hamartoma" }, { "code": "EA91.Y", "title": "Other specified lichen planus" }, { "code": "LB03.Y", "title": "Other specified structural developmental anomalies of umbilical cord" } ]	=== ICD-11 CODES FOUND === [ED6Y] Other specified disorders of skin pigmentation Also known as: Other specified disorders of skin pigmentation \| Non-melanin pigmentation due to ingested or injected substance \| Carotenoderma \| Argyria \| Chrysiasis [NE60] Harmful effects of drugs, medicaments or biological substances, not elsewhere classified Also known as: Harmful effects of drugs, medicaments or biological substances, not elsewhere classified \| drugs, medicaments or biological substances, toxicity not elsewhere classified \| adverse drug effects \| drug reaction NOS \| drug allergy NOS Excludes: Alcohol intoxication \| pathological drug intoxication \| hypersensitivity reaction to correctly administered drug [EK12] Allergic contact sensitisation Definition: The presence of specific delayed type IV hypersensitivity of the immune system to a given substance without imputation of past or current disease. Such sensitisation is normally acquired by prior contact of the skin or mucous membranes with the substance or with one chemically closely related to it (cross-reactivity). Subsequent contact with the substance may provoke an allergic reaction. In certain circumstances such sensitisation may prevent an individual from taking up or continuing employmen Also known as: Allergic contact sensitisation \| Allergic contact sensitisation organised by allergen class \| Allergic contact sensitisation to allergens from clothing or footwear \| Allergic contact sensitisation to cosmetics or fragrances \| Allergic contact sensitisation to dental materials [PL00] Drugs, medicaments or biological substances associated with injury or harm in therapeutic use Also known as: Drugs, medicaments or biological substances associated with injury or harm in therapeutic use \| Drugs medicaments or biological substances associated with injury or harm in therapeutic use, Systemic antibiotics \| Drugs medicaments or biological substances associated with injury or harm in therapeutic use, Systemic antibiotics, Penicillins \| Drugs medicaments or biological substances associated with injury or harm in therapeutic use, Systemic antibiotics, Cephalosporins or other beta-lactam antibiotics \| Drugs medicaments or biological substances associated with injury or harm in therapeutic use, Systemic antibiotics, Chloramphenicol group Excludes: Circumstances associated with exposure to a drug, medicament or biological substance influencing the episode of care without injury or harm [EK00.C] Allergic contact dermatitis due to topical medicaments Definition: Allergic contact dermatitis due to exposure to topical medicaments such as corticosteroids, antibiotics, antimycotics, disinfectants, local anaesthetics or NSAIDs. Also known as: Allergic contact dermatitis due to topical medicaments \| Allergic contact eczema due to topical medicaments \| allergic contact dermatitis due to drugs in contact with skin \| Occupational allergic contact dermatitis due to topical medicaments \| Nonoccupational allergic contact dermatitis due to topical medicaments [EB61.1] Linear morphoea Definition: Linear morphoea is a form of morphoea which usually presents in childhood or adolescence and is usually unilateral, affecting a limb with a linear induration of skin, subcutis and occasionally underlying muscle and bone. It may also affect the scalp and forehead ("en coup de sabre") producing a depressed scar likened to a healed sabre wound, with sclerosis of the skin and alopecia of affected scalp. Also known as: Linear morphoea \| Linear scleroderma \| Morphoea en coup de sabre [EB42] Linear IgA bullous dermatosis Definition: Linear IgA bullous dermatosis is an uncommon immunobullous disorder which occurs in both adults and children. It is characterised by linear deposition of IgA along the epidermal basement membrane. Although the clinical picture may resemble dermatitis herpetiformis, it is not associated with gluten enteropathy and it has different clinical and immunopathological attributes. Also known as: Linear IgA bullous dermatosis \| Linear IgA disease \| Childhood linear IgA bullous dermatosis \| Linear IgA bullous dermatosis, childhood form \| Chronic bullous disease of childhood [LC00.Y] Other specified keratinocytic epidermal hamartoma Also known as: Other specified keratinocytic epidermal hamartoma \| Verrucous epidermal naevus \| Naevus verrucosus \| Non-epidermolytic verrucous epidermal naevus \| Epidermolytic verrucous epidermal naevus [EA91.Y] Other specified lichen planus Also known as: Other specified lichen planus \| Miscellaneous specified forms of lichen planus \| Annular lichen planus \| Atrophic lichen planus \| Bullous lichen planus [LB03.Y] Other specified structural developmental anomalies of umbilical cord Also known as: Other specified structural developmental anomalies of umbilical cord \| Umbilical cord calcifications \| Omphalomesenteric duct remnants or cysts \| Vitelline duct remnants and cysts \| Persistent omphalomesenteric duct === GRAPH WALKS === --- Walk 1 --- [ED6Y] Other specified disorders of skin pigmentation --PARENT--> [?] Disorders of skin colour Def: This group includes not only abnormalities of melanin pigmentation (e.g. vitiligo and melasma) but also skin colour changes due to other pigments (e.g. carotenaemia and argyria).... --CHILD--> [ED60] Acquired hypermelanosis Def: Increased melanin pigmentation of the skin resulting from disease or from other stimuli including ultraviolet radiation and hormones.... --- Walk 2 --- [ED6Y] Other specified disorders of skin pigmentation --PARENT--> [?] Disorders of skin colour Def: This group includes not only abnormalities of melanin pigmentation (e.g. vitiligo and melasma) but also skin colour changes due to other pigments (e.g. carotenaemia and argyria).... --PARENT--> [?] Disorders of the epidermis and epidermal appendages Def: This group incorporates skin disorders involving principally the epidermis, including abnormalities of keratinization and pigmentation, and the epidermal appendages, namely the hair follicular unit (h... --- Walk 3 --- [NE60] Harmful effects of drugs, medicaments or biological substances, not elsewhere classified --PARENT--> [?] Harmful effects of substances --CHILD--> [NE6Z] Harmful effects of unspecified substance --- Walk 4 --- [NE60] Harmful effects of drugs, medicaments or biological substances, not elsewhere classified --EXCLUDES--> [?] Allergic or hypersensitivity conditions Def: Allergy is a hypersensitivity reaction initiated by proven immunologic mechanisms. Hypersensitivity is defined as conditions clinically resembling allergy that cause objectively reproducible symptoms... --CHILD--> [?] Allergic or hypersensitivity disorders involving the eye Def: Allergic or hypersensitivity disorders involving the eye includes several clinically different conditions that can be considered as hypersensitivity disorders of the ocular surface. The classification... --- Walk 5 --- [EK12] Allergic contact sensitisation Def: The presence of specific delayed type IV hypersensitivity of the immune system to a given substance without imputation of past or current disease. Such sensitisation is normally acquired by prior cont... --PARENT--> [?] Skin disorders provoked by external factors Def: A large group of skin disorders due to exposure of the skin to various external physical, chemical or environmental insults including chemical irritants and allergens, poisons, pressure, cold, heat, s... --CHILD--> [EH90] Pressure ulceration Def: Pressure ulcers result from localised injury and ischaemic necrosis of skin and underlying tissues due to prolonged pressure, or pressure in combination with shear; bony prominences of the body are th... --- Walk 6 --- [EK12] Allergic contact sensitisation Def: The presence of specific delayed type IV hypersensitivity of the immune system to a given substance without imputation of past or current disease. Such sensitisation is normally acquired by prior cont... --PARENT--> [?] Skin disorders provoked by external factors Def: A large group of skin disorders due to exposure of the skin to various external physical, chemical or environmental insults including chemical irritants and allergens, poisons, pressure, cold, heat, s... --RELATED_TO--> [?] Hand and arm vibration syndrome Def: Hand Transmitted Vibration is mechanical vibration arising from powered processes or tools which enters the body at the fingers or the palm of the hands. As a consequence of this exposure some people ...	[ "[ED6Y] Other specified disorders of skin pigmentation\n --PARENT--> [?] Disorders of skin colour\n Def: This group includes not only abnormalities of melanin pigmentation (e.g. vitiligo and melasma) but also skin colour changes due to other pigments (e.g. carotenaemia and argyria)....\n --CHILD--> [ED60] Acquired hypermelanosis\n Def: Increased melanin pigmentation of the skin resulting from disease or from other stimuli including ultraviolet radiation and hormones....", "[ED6Y] Other specified disorders of skin pigmentation\n --PARENT--> [?] Disorders of skin colour\n Def: This group includes not only abnormalities of melanin pigmentation (e.g. vitiligo and melasma) but also skin colour changes due to other pigments (e.g. carotenaemia and argyria)....\n --PARENT--> [?] Disorders of the epidermis and epidermal appendages\n Def: This group incorporates skin disorders involving principally the epidermis, including abnormalities of keratinization and pigmentation, and the epidermal appendages, namely the hair follicular unit (h...", "[NE60] Harmful effects of drugs, medicaments or biological substances, not elsewhere classified\n --PARENT--> [?] Harmful effects of substances\n --CHILD--> [NE6Z] Harmful effects of unspecified substance", "[NE60] Harmful effects of drugs, medicaments or biological substances, not elsewhere classified\n --EXCLUDES--> [?] Allergic or hypersensitivity conditions\n Def: Allergy is a hypersensitivity reaction initiated by proven immunologic mechanisms.\n\nHypersensitivity is defined as conditions clinically resembling allergy that cause objectively reproducible symptoms...\n --CHILD--> [?] Allergic or hypersensitivity disorders involving the eye\n Def: Allergic or hypersensitivity disorders involving the eye includes several clinically different conditions that can be considered as hypersensitivity disorders of the ocular surface. The classification...", "[EK12] Allergic contact sensitisation\n Def: The presence of specific delayed type IV hypersensitivity of the immune system to a given substance without imputation of past or current disease. Such sensitisation is normally acquired by prior cont...\n --PARENT--> [?] Skin disorders provoked by external factors\n Def: A large group of skin disorders due to exposure of the skin to various external physical, chemical or environmental insults including chemical irritants and allergens, poisons, pressure, cold, heat, s...\n --CHILD--> [EH90] Pressure ulceration\n Def: Pressure ulcers result from localised injury and ischaemic necrosis of skin and underlying tissues due to prolonged pressure, or pressure in combination with shear; bony prominences of the body are th...", "[EK12] Allergic contact sensitisation\n Def: The presence of specific delayed type IV hypersensitivity of the immune system to a given substance without imputation of past or current disease. Such sensitisation is normally acquired by prior cont...\n --PARENT--> [?] Skin disorders provoked by external factors\n Def: A large group of skin disorders due to exposure of the skin to various external physical, chemical or environmental insults including chemical irritants and allergens, poisons, pressure, cold, heat, s...\n --RELATED_TO--> [?] Hand and arm vibration syndrome\n Def: Hand Transmitted Vibration is mechanical vibration arising from powered processes or tools which enters the body at the fingers or the palm of the hands. As a consequence of this exposure some people ..." ]	ED6Y	Other specified disorders of skin pigmentation	[ { "from_icd11": "ED6Y", "icd10_code": "L814", "icd10_title": "Other melanin hyperpigmentation" }, { "from_icd11": "NE60", "icd10_code": "T50A95A", "icd10_title": "Adverse effect of other bacterial vaccines, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50Z15A", "icd10_title": "Adverse effect of immunoglobulin, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50Z95A", "icd10_title": "Adverse effect of other vaccines and biological substances, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50A95S", "icd10_title": "Adverse effect of other bacterial vaccines, sequela" }, { "from_icd11": "NE60", "icd10_code": "T50B95A", "icd10_title": "Adverse effect of other viral vaccines, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50A25A", "icd10_title": "Adverse effect of mixed bacterial vaccines without a pertussis component, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50A91A", "icd10_title": "Poisoning by other bacterial vaccines, accidental (unintentional), initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T498X5A", "icd10_title": "Adverse effect of other topical agents, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T48905A", "icd10_title": "Adverse effect of unspecified agents primarily acting on the respiratory system, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T48995A", "icd10_title": "Adverse effect of other agents primarily acting on the respiratory system, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50A15A", "icd10_title": "Adverse effect of pertussis vaccine, including combinations with a pertussis component, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T50B15A", "icd10_title": "Adverse effect of smallpox vaccines, initial encounter" }, { "from_icd11": "NE60", "icd10_code": "T416X3A", "icd10_title": "" }, { "from_icd11": "NE60", "icd10_code": "T419X3A", "icd10_title": "" } ]	L814	Other melanin hyperpigmentation
A 64-year-old female patient presented to the hospital for single-catheter coronary angiography due to persistent chest tightness in the precordial region. The 5F left and right coronal contrast catheters were placed transthecally to allow coronary angiography at multiple projection angles. Postoperatively, the right radial artery was routinely compressed for 24 h using a radial artery compression hemostat (WORK) to stop the bleeding. On the day following the procedure, the patient experienced no redness, swelling, fever, or pain on the right limb; however, the patient had a rash on the right upper limb . The rash was red, wrinkled, not raised, and well-circumscribed. Ultrasound Doppler examination of the hand was not performed while the rash was present. The patient had a 6-year history of hypertension and previous regular use of Candesartan cilexetil. The patient previously had hyperlipidemia and regularly used Atorvastatin, with normal platelet count, prothrombin time, and activated partial thromboplastin clotting time (APTT) values. The patient's arterial pulsatility was normal. At symptom onset, the patient had a blood pressure of 190/120 mmHg and a platelet count of 167 × 10 9 /L. The patient's rash resolved without treatment after 3 days. The rash timeline is shown in Fig. 4 . Fig. 1 Rumpel-Leede Sign (Hands contrast) Fig. 2 Rumpel-Leede Sign Fig. 3 Rumpel-Leede Sign Fig. 4 The rash timeline	3.785156	0.985352	sec[1]/p[0]	en	0.999998	PMC9316747	https://doi.org/10.1186/s12872-022-02767-7	[ "rash", "rumpel", "leede", "coronary", "angiography", "contrast", "radial", "artery", "limb", "platelet" ]	[ { "code": "ME66.6Z", "title": "Rash, unspecified" }, { "code": "ME66.6Y", "title": "Other specified rash" }, { "code": "ME62", "title": "Acute skin eruption of uncertain or unspecified nature" }, { "code": "ME63", "title": "Chronic skin disorder of uncertain or unspecified nature" }, { "code": "EA00", "title": "Viral exanthem due to unknown or unspecified agent" }, { "code": "BA8Z", "title": "Diseases of coronary artery, unspecified" }, { "code": "BA4Z", "title": "Acute ischaemic heart disease, unspecified" }, { "code": "BA41.Z", "title": "Acute myocardial infarction, unspecified" }, { "code": "BA5Z", "title": "Chronic ischaemic heart disease, unspecified" }, { "code": "LA8C.2", "title": "Congenital coronary arterial fistula" } ]	=== ICD-11 CODES FOUND === [ME66.6Z] Rash, unspecified Also known as: Rash, unspecified \| Rash \| skin rash NOS [ME66.6Y] Other specified rash Also known as: Other specified rash [ME62] Acute skin eruption of uncertain or unspecified nature Definition: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature. Also known as: Acute skin eruption of uncertain or unspecified nature \| Acute skin eruption without established diagnosis \| Acute rash \| Acute pustular skin eruption Excludes: Drug eruptions [ME63] Chronic skin disorder of uncertain or unspecified nature Definition: A provisional diagnosis for a chronic skin disorder (of at least six weeks' duration) of unknown, uncertain or unspecified nature. Also known as: Chronic skin disorder of uncertain or unspecified nature \| Chronic skin disorder without established diagnosis \| Chronic rash [EA00] Viral exanthem due to unknown or unspecified agent Definition: An exanthematic rash with symptoms suggestive of a viral aetiology where the agent is either unknown or unspecified. Also known as: Viral exanthem due to unknown or unspecified agent \| Viral exanthem \| viral rash NOS \| virus exanthema \| nonspecific exanthematous viral infection [BA8Z] Diseases of coronary artery, unspecified Also known as: Diseases of coronary artery, unspecified \| coronary artery insufficiency \| coronary artery heart disease \| CAD - [coronary artery disease] \| coronary artery disorder [BA4Z] Acute ischaemic heart disease, unspecified Also known as: Acute ischaemic heart disease, unspecified \| acute coronary syndrome \| ACS - [acute coronary syndrome] \| Silent myocardial ischaemia \| asymptomatic ischemia [BA41.Z] Acute myocardial infarction, unspecified Also known as: Acute myocardial infarction, unspecified \| Acute myocardial infarction \| cardiac attack \| heart attack \| acute cardiac infarction [BA5Z] Chronic ischaemic heart disease, unspecified Also known as: Chronic ischaemic heart disease, unspecified \| Ischaemic heart disease (chronic) NOS \| coronary ischaemia \| coronary damage NOS \| atheroma of heart [LA8C.2] Congenital coronary arterial fistula Definition: A congenital cardiovascular malformation in which a coronary artery communicates, through an anomalous channel, with a cardiac chamber or with any segment of the systemic or pulmonary circulation. Additional information: this communication may be simple and direct or may be tortuous and dilated. In order of frequency the involved coronary artery is the right, the left and, rarely, both coronary arteries. Occasionally multiple fistulas are present. Also known as: Congenital coronary arterial fistula \| coronary fistula \| congenital arteriovenous coronary fistula \| congenital coronary fistula to pulmonary artery \| Congenital coronary arterial fistula to right ventricle Includes: congenital coronary fistula to pulmonary artery Excludes: anomalous origin of coronary artery from pulmonary arterial tree === GRAPH WALKS === --- Walk 1 --- [ME66.6Z] Rash, unspecified --PARENT--> [ME66.6] Rash Def: A non-specific term indicating the presence of an acquired skin disturbance to be used only when no more precise information is available.... --EXCLUDES--> [?] Chronic skin disorder of uncertain or unspecified nature Def: A provisional diagnosis for a chronic skin disorder (of at least six weeks' duration) of unknown, uncertain or unspecified nature.... --- Walk 2 --- [ME66.6Z] Rash, unspecified --PARENT--> [ME66.6] Rash Def: A non-specific term indicating the presence of an acquired skin disturbance to be used only when no more precise information is available.... --EXCLUDES--> [?] Chronic skin disorder of uncertain or unspecified nature Def: A provisional diagnosis for a chronic skin disorder (of at least six weeks' duration) of unknown, uncertain or unspecified nature.... --- Walk 3 --- [ME66.6Y] Other specified rash --PARENT--> [ME66.6] Rash Def: A non-specific term indicating the presence of an acquired skin disturbance to be used only when no more precise information is available.... --EXCLUDES--> [?] Chronic skin disorder of uncertain or unspecified nature Def: A provisional diagnosis for a chronic skin disorder (of at least six weeks' duration) of unknown, uncertain or unspecified nature.... --- Walk 4 --- [ME66.6Y] Other specified rash --PARENT--> [ME66.6] Rash Def: A non-specific term indicating the presence of an acquired skin disturbance to be used only when no more precise information is available.... --EXCLUDES--> [?] Acute skin eruption of uncertain or unspecified nature Def: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature.... --- Walk 5 --- [ME62] Acute skin eruption of uncertain or unspecified nature Def: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature.... --CHILD--> [ME62.0] Acute erythematous skin eruption Def: A provisional diagnosis for a skin eruption of unknown or uncertain nature which arises abruptly and consists predominantly of diffuse cutaneous erythema. A classical cause is scarlet fever but reacti... --PARENT--> [ME62] Acute skin eruption of uncertain or unspecified nature Def: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature.... --- Walk 6 --- [ME62] Acute skin eruption of uncertain or unspecified nature Def: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature.... --CHILD--> [ME62.1] Acute purpuric skin eruption Def: A provisional diagnosis for a skin eruption of unknown or uncertain nature which arises abruptly and consists predominantly of disseminated purpura. Potential causes are numerous and include thrombocy... --PARENT--> [ME62] Acute skin eruption of uncertain or unspecified nature Def: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature....	[ "[ME66.6Z] Rash, unspecified\n --PARENT--> [ME66.6] Rash\n Def: A non-specific term indicating the presence of an acquired skin disturbance to be used only when no more precise information is available....\n --EXCLUDES--> [?] Chronic skin disorder of uncertain or unspecified nature\n Def: A provisional diagnosis for a chronic skin disorder (of at least six weeks' duration) of unknown, uncertain or unspecified nature....", "[ME66.6Z] Rash, unspecified\n --PARENT--> [ME66.6] Rash\n Def: A non-specific term indicating the presence of an acquired skin disturbance to be used only when no more precise information is available....\n --EXCLUDES--> [?] Chronic skin disorder of uncertain or unspecified nature\n Def: A provisional diagnosis for a chronic skin disorder (of at least six weeks' duration) of unknown, uncertain or unspecified nature....", "[ME66.6Y] Other specified rash\n --PARENT--> [ME66.6] Rash\n Def: A non-specific term indicating the presence of an acquired skin disturbance to be used only when no more precise information is available....\n --EXCLUDES--> [?] Chronic skin disorder of uncertain or unspecified nature\n Def: A provisional diagnosis for a chronic skin disorder (of at least six weeks' duration) of unknown, uncertain or unspecified nature....", "[ME66.6Y] Other specified rash\n --PARENT--> [ME66.6] Rash\n Def: A non-specific term indicating the presence of an acquired skin disturbance to be used only when no more precise information is available....\n --EXCLUDES--> [?] Acute skin eruption of uncertain or unspecified nature\n Def: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature....", "[ME62] Acute skin eruption of uncertain or unspecified nature\n Def: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature....\n --CHILD--> [ME62.0] Acute erythematous skin eruption\n Def: A provisional diagnosis for a skin eruption of unknown or uncertain nature which arises abruptly and consists predominantly of diffuse cutaneous erythema. A classical cause is scarlet fever but reacti...\n --PARENT--> [ME62] Acute skin eruption of uncertain or unspecified nature\n Def: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature....", "[ME62] Acute skin eruption of uncertain or unspecified nature\n Def: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature....\n --CHILD--> [ME62.1] Acute purpuric skin eruption\n Def: A provisional diagnosis for a skin eruption of unknown or uncertain nature which arises abruptly and consists predominantly of disseminated purpura. Potential causes are numerous and include thrombocy...\n --PARENT--> [ME62] Acute skin eruption of uncertain or unspecified nature\n Def: A provisional diagnosis for an acute skin eruption of less than six weeks' duration of unknown, uncertain or unspecified nature...." ]	ME66.6Z	Rash, unspecified	[ { "from_icd11": "ME62", "icd10_code": "R21", "icd10_title": "Rash and other nonspecific skin eruption" }, { "from_icd11": "ME62", "icd10_code": "R20-R23", "icd10_title": "" }, { "from_icd11": "ME63", "icd10_code": "L989", "icd10_title": "Disorder of the skin and subcutaneous tissue, unspecified" }, { "from_icd11": "BA4Z", "icd10_code": "I248", "icd10_title": "Other forms of acute ischemic heart disease" }, { "from_icd11": "BA4Z", "icd10_code": "I256", "icd10_title": "Silent myocardial ischemia" }, { "from_icd11": "BA4Z", "icd10_code": "I249", "icd10_title": "Acute ischemic heart disease, unspecified" }, { "from_icd11": "BA4Z", "icd10_code": "I24", "icd10_title": "Other acute ischemic heart diseases" }, { "from_icd11": "BA41.Z", "icd10_code": "I21A1", "icd10_title": "Myocardial infarction type 2" }, { "from_icd11": "BA41.Z", "icd10_code": "I21A9", "icd10_title": "Other myocardial infarction type" }, { "from_icd11": "BA41.Z", "icd10_code": "I2109", "icd10_title": "ST elevation (STEMI) myocardial infarction involving other coronary artery of anterior wall" }, { "from_icd11": "BA41.Z", "icd10_code": "I2119", "icd10_title": "ST elevation (STEMI) myocardial infarction involving other coronary artery of inferior wall" }, { "from_icd11": "BA41.Z", "icd10_code": "I2111", "icd10_title": "ST elevation (STEMI) myocardial infarction involving right coronary artery" }, { "from_icd11": "BA41.Z", "icd10_code": "I2102", "icd10_title": "ST elevation (STEMI) myocardial infarction involving left anterior descending coronary artery" }, { "from_icd11": "BA41.Z", "icd10_code": "I2129", "icd10_title": "ST elevation (STEMI) myocardial infarction involving other sites" }, { "from_icd11": "BA41.Z", "icd10_code": "I2121", "icd10_title": "ST elevation (STEMI) myocardial infarction involving left circumflex coronary artery" } ]	R21	Rash and other nonspecific skin eruption
After discharge, the patient continued to receive treatments, including oral antihyperthyroidism (methimazole), anticoagulation (rivaroxaban), and rehabilitation exercises. Half a year after discharge, the grand movement ability and muscle strength of his right upper limb gradually recovered. However, the fine movements of his right hand were still imperfect, and his language presentation skills were slightly impaired. His MRI on July 8th revealed a focal lesion of encephalomalacia with gliosis in the left parieto-occipital lobes and recanalization of the previously blocked venous sinuses, and a small thrombus was still visible in the left transverse sinus and sinus confluence . His hyperthyroidism was well controlled, with an FT3 of 5.5 pmol/L (NR: 3.1 ~ 6.8) and an FT4 of 15.5 pmol/L (NR: 12 ~ 22). He continues to take oral medication and undergo physical rehabilitation. Fig. 4 A-C Reexamination of MRI half a year after discharge: A Recanalization of the superior sagittal sinus, straight sinus, sinus confluence, and a small thrombus was still visible near the sinus confluence; B Good enhancement was seen in the sinus confluence and bilateral transverse sinuses, and some residual thrombus could be seen in the initial segments of the bilateral transverse sinuses; C MRI showed a focal lesion of encephalomalacia with gliosis in the left parieto-occipital lobes. The white solid arrows show the lesions	3.925781	0.979492	sec[1]/p[2]	en	0.999996	PMC9261005	https://doi.org/10.1186/s12883-022-02777-0	[ "sinus", "confluence", "still", "sinuses", "thrombus", "transverse", "oral", "rehabilitation", "half", "lesion" ]	[ { "code": "CA0A.Z", "title": "Chronic rhinosinusitis, unspecified" }, { "code": "CA0Y&XA3523", "title": "Nasal sinus obstruction" }, { "code": "CA0J.Y", "title": "Other specified nasal polyp" }, { "code": "LB03.Y", "title": "Other specified structural developmental anomalies of umbilical cord" }, { "code": "DA09.61", "title": "Periapical abscess with sinus" }, { "code": "FA24.4", "title": "Juvenile systemic arthritis" }, { "code": "KD3B.Z", "title": "Unspecified time of fetal death, cause not specified" }, { "code": "QA46.1", "title": "Single stillbirth" }, { "code": "FA23", "title": "Adult-onset Still disease" }, { "code": "KD3B.0", "title": "Antepartum fetal death" } ]	=== ICD-11 CODES FOUND === [CA0A.Z] Chronic rhinosinusitis, unspecified Also known as: Chronic rhinosinusitis, unspecified \| Chronic rhinosinusitis \| Chronic sinusitis \| chronic sinusitis NOS \| unspecified sinusitis [CA0J.Y] Other specified nasal polyp Also known as: Other specified nasal polyp \| Polyp of nasal cavity \| Polyp of the nasopharynx \| nasopharyngeal polyp \| Polyp of adenoid tissue [LB03.Y] Other specified structural developmental anomalies of umbilical cord Also known as: Other specified structural developmental anomalies of umbilical cord \| Umbilical cord calcifications \| Omphalomesenteric duct remnants or cysts \| Vitelline duct remnants and cysts \| Persistent omphalomesenteric duct [DA09.61] Periapical abscess with sinus Also known as: Periapical abscess with sinus \| Dental abscess with sinus \| Dentoalveolar abscess with sinus \| Dental sinus \| periapical abscess fistula Includes: Dental abscess with sinus \| Dentoalveolar abscess with sinus \| Dental sinus [FA24.4] Juvenile systemic arthritis Definition: Systemic-onset juvenile idiopathic arthritis represents 10-11% of cases of juvenile idiopathic arthritis (JIA) and is marked by the severity of the extra-articular manifestations (fever, cutaneous eruptions) and by an equal sex ratio. Fever peaks are associated with transient cutaneous eruptions and diffuse erythematosis or urticarial-like lesions. The presence of arthritis is essential for diagnosis but may appear later in the disease course. The number of sites affected is variable (mono-, oli Also known as: Juvenile systemic arthritis \| Still disease \| Juvenile systemic onset arthritis complicated by macrophage activation syndrome \| Juvenile systemic arthritis, multiple sites \| juvenile arthritis with systemic onset, multiple sites [KD3B.Z] Unspecified time of fetal death, cause not specified Also known as: Unspecified time of fetal death, cause not specified \| Fetal death, cause not specified \| stillbirth NOS \| stillborn NOS \| intrauterine fetal demise [QA46.1] Single stillbirth Definition: Stillbirth is the complete expulsion or extraction from a woman of a fetus, following its death prior to the complete expulsion or extraction, at 22 or more completed weeks of gestation. Stillbirths are distinct from cases of induced abortion. When information on gestational age is unavailable use birthweight 500 grams and more as the criteria. Also known as: Single stillbirth \| outcome of delivery of single stillborn [FA23] Adult-onset Still disease Definition: Adult onset Still's disease is a rare rheumatic condition characterised by a combination of symptoms, such as fever higher than 39 degrees C, cutaneous rash during fever peaks, joint or muscle pain, lymph node hypertrophy, increase of white blood cells (especially polymorphonuclear neutrophils) and abnormalities of liver metabolism. Also known as: Adult-onset Still disease \| Adult-onset Still disease, multiple sites \| Adult-onset Still disease, shoulder region \| Adult-onset Still disease, acromioclavicular joint \| Adult-onset Still disease, glenohumeral joint Excludes: Still disease NOS [KD3B.0] Antepartum fetal death Definition: Antepartum fetal death is a fetal death before the onset of labour. If vital status of the fetus at the onset of labour is unknown, consider it was antepartum if there is presence of signs of maceration at the time of delivery. Macerated stillbirth - is the complete expulsion or extraction from a woman of a fetus following a fetal death at 22 or more completed weeks of gestation; or if gestational age is not available with a birthweight of 500g or more with skin showing signs of maceration. An Also known as: Antepartum fetal death \| macerated stillbirth \| antepartum stillbirth Includes: macerated stillbirth \| antepartum stillbirth === GRAPH WALKS === --- Walk 1 --- [CA0A.Z] Chronic rhinosinusitis, unspecified --PARENT--> [CA0A] Chronic rhinosinusitis Def: Sinusitis is an inflammation of the mucosal lining of the paranasal sinuses secondary to both infectious and allergic mechanisms. The retention of sinus secretions is the most important event in the d... --CHILD--> [CA0A.Y] Other specified chronic rhinosinusitis --- Walk 2 --- [CA0A.Z] Chronic rhinosinusitis, unspecified --PARENT--> [CA0A] Chronic rhinosinusitis Def: Sinusitis is an inflammation of the mucosal lining of the paranasal sinuses secondary to both infectious and allergic mechanisms. The retention of sinus secretions is the most important event in the d... --CHILD--> [CA0A.Z] Chronic rhinosinusitis, unspecified --- Walk 3 --- [CA0J.Y] Other specified nasal polyp --PARENT--> [CA0J] Nasal polyp Def: Nasal polyp is an inflammatory and proliferating mass arising from the epithelial linings of nasal cavity and paranasal sinuses. In general, nasal polyp appears to be greyish white, smoothly surfaced,... --EXCLUDES--> [?] Benign neoplasm of middle ear, nasal cavity or accessory sinuses --- Walk 4 --- [CA0J.Y] Other specified nasal polyp --PARENT--> [CA0J] Nasal polyp Def: Nasal polyp is an inflammatory and proliferating mass arising from the epithelial linings of nasal cavity and paranasal sinuses. In general, nasal polyp appears to be greyish white, smoothly surfaced,... --CHILD--> [CA0J.Z] Nasal polyp, unspecified --- Walk 5 --- [LB03.Y] Other specified structural developmental anomalies of umbilical cord --PARENT--> [LB03] Structural developmental anomalies of umbilical cord Def: Any condition caused by failure of the umbilical cord to correctly develop during the antenatal period.... --CHILD--> [LB03.1] Single umbilical cord artery Def: A single umbilical artery arising from either the allantoic arterial system (Type I) or vitelline artery (Type II). It has been associated with renal anomalies.... --- Walk 6 --- [LB03.Y] Other specified structural developmental anomalies of umbilical cord --PARENT--> [LB03] Structural developmental anomalies of umbilical cord Def: Any condition caused by failure of the umbilical cord to correctly develop during the antenatal period.... --RELATED_TO--> [?] Fetus or newborn affected by long umbilical cord Def: An umbilical cord > 2 SD in length above mean for the gestational age. At term, this is > 80 cm....	[ "[CA0A.Z] Chronic rhinosinusitis, unspecified\n --PARENT--> [CA0A] Chronic rhinosinusitis\n Def: Sinusitis is an inflammation of the mucosal lining of the paranasal sinuses secondary to both infectious and allergic mechanisms. The retention of sinus secretions is the most important event in the d...\n --CHILD--> [CA0A.Y] Other specified chronic rhinosinusitis", "[CA0A.Z] Chronic rhinosinusitis, unspecified\n --PARENT--> [CA0A] Chronic rhinosinusitis\n Def: Sinusitis is an inflammation of the mucosal lining of the paranasal sinuses secondary to both infectious and allergic mechanisms. The retention of sinus secretions is the most important event in the d...\n --CHILD--> [CA0A.Z] Chronic rhinosinusitis, unspecified", "[CA0J.Y] Other specified nasal polyp\n --PARENT--> [CA0J] Nasal polyp\n Def: Nasal polyp is an inflammatory and proliferating mass arising from the epithelial linings of nasal cavity and paranasal sinuses. In general, nasal polyp appears to be greyish white, smoothly surfaced,...\n --EXCLUDES--> [?] Benign neoplasm of middle ear, nasal cavity or accessory sinuses", "[CA0J.Y] Other specified nasal polyp\n --PARENT--> [CA0J] Nasal polyp\n Def: Nasal polyp is an inflammatory and proliferating mass arising from the epithelial linings of nasal cavity and paranasal sinuses. In general, nasal polyp appears to be greyish white, smoothly surfaced,...\n --CHILD--> [CA0J.Z] Nasal polyp, unspecified", "[LB03.Y] Other specified structural developmental anomalies of umbilical cord\n --PARENT--> [LB03] Structural developmental anomalies of umbilical cord\n Def: Any condition caused by failure of the umbilical cord to correctly develop during the antenatal period....\n --CHILD--> [LB03.1] Single umbilical cord artery\n Def: A single umbilical artery arising from either the allantoic arterial system (Type I) or vitelline artery (Type II). It has been associated with renal anomalies....", "[LB03.Y] Other specified structural developmental anomalies of umbilical cord\n --PARENT--> [LB03] Structural developmental anomalies of umbilical cord\n Def: Any condition caused by failure of the umbilical cord to correctly develop during the antenatal period....\n --RELATED_TO--> [?] Fetus or newborn affected by long umbilical cord\n Def: An umbilical cord > 2 SD in length above mean for the gestational age. At term, this is > 80 cm...." ]	CA0A.Z	Chronic rhinosinusitis, unspecified	[ { "from_icd11": "CA0A.Z", "icd10_code": "J329", "icd10_title": "Chronic sinusitis, unspecified" }, { "from_icd11": "CA0A.Z", "icd10_code": "J324", "icd10_title": "Chronic pansinusitis" }, { "from_icd11": "CA0A.Z", "icd10_code": "J320", "icd10_title": "Chronic maxillary sinusitis" }, { "from_icd11": "CA0A.Z", "icd10_code": "J322", "icd10_title": "Chronic ethmoidal sinusitis" }, { "from_icd11": "CA0A.Z", "icd10_code": "J323", "icd10_title": "Chronic sphenoidal sinusitis" }, { "from_icd11": "CA0A.Z", "icd10_code": "J328", "icd10_title": "Other chronic sinusitis" }, { "from_icd11": "CA0A.Z", "icd10_code": "J321", "icd10_title": "Chronic frontal sinusitis" }, { "from_icd11": "CA0A.Z", "icd10_code": "J30-J39", "icd10_title": "" }, { "from_icd11": "CA0A.Z", "icd10_code": "J32", "icd10_title": "Chronic sinusitis" }, { "from_icd11": "DA09.61", "icd10_code": "K046", "icd10_title": "Periapical abscess with sinus" }, { "from_icd11": "FA24.4", "icd10_code": "M0820", "icd10_title": "Juvenile rheumatoid arthritis with systemic onset, unspecified site" }, { "from_icd11": "FA24.4", "icd10_code": "M082", "icd10_title": "Juvenile rheumatoid arthritis with systemic onset" }, { "from_icd11": "KD3B.Z", "icd10_code": "P95", "icd10_title": "Stillbirth" }, { "from_icd11": "QA46.1", "icd10_code": "Z371", "icd10_title": "Single stillbirth" }, { "from_icd11": "FA23", "icd10_code": "M061", "icd10_title": "Adult-onset Still's disease" } ]	J329	Chronic sinusitis, unspecified
Based on the histopathological findings, the patient was diagnosed with colonic basidiobolomycosis. Polymerase chain reaction testing was not available. Thus, the family was contacted, and the patient was readmitted for further therapy. The patient was initially administered intravenous (IV) voriconazole (7 mg/kg/dose every 12 h) with continuous monitoring of liver function. Detailed history-taking revealed that the patient played in the soil and swam in a small local lake. One week after the second admission, the patient developed abdominal pain, nausea, and vomiting, intolerance to oral intake of food, and constipation. Laboratory findings showed a WBC count of 23,000 cells/μL with mainly neutrophils, and normal hemoglobin, platelets, and electrolyte levels. Abdominal ultrasonography was requested based on a surgical consultation, and the findings were suggestive of small bowel obstruction representing adhesive bands. A decision was made to manage the bowel obstruction conservatively, and a nasogastric tube was inserted for free drainage. However, the infectious disease team suspected a healthcare-associated infection and initiated IV piperacillin-tazobactam. The patient did not show much improvement, and piperacillin-tazobactam was replaced with meropenem. Subsequently, the patient’s clinical condition improved, the abdominal pain resolved, and the patient was able to resume oral intake of food.	3.765625	0.982422	sec[1]/p[7]	en	0.999996	PMC9297541	https://doi.org/10.1186/s12887-022-03495-9	[ "abdominal", "based", "small", "pain", "oral", "intake", "food", "bowel", "obstruction", "piperacillin" ]	[ { "code": "MD81.3", "title": "Acute abdomen" }, { "code": "JA01.0", "title": "Abdominal pregnancy" }, { "code": "ME04.Z", "title": "Ascites, unspecified" }, { "code": "NB51.0&XA3KX0", "title": "Laceration without foreign body of abdominal wall" }, { "code": "NB9Y", "title": "Other specified injuries to the abdomen, lower back, lumbar spine or pelvis" }, { "code": "5C75", "title": "Mixed disorder of acid-base balance" }, { "code": "NA02.1Z", "title": "Fracture of base of skull, unspecified" }, { "code": "NA02.70", "title": "Fracture of condylar process of mandible" }, { "code": "NC53.2", "title": "Fracture of first metacarpal bone" }, { "code": "NA02.1A", "title": "Other fractures of base of skull" } ]	=== ICD-11 CODES FOUND === [MD81.3] Acute abdomen Definition: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases Also known as: Acute abdomen \| acute abdominal pain syndrome \| surgical abdomen \| abdominal acute syndrome \| severe abdomen pain [JA01.0] Abdominal pregnancy Definition: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy. Also known as: Abdominal pregnancy \| abdomen pregnancy \| intraperitoneal pregnancy Excludes: Maternal care for viable fetus in abdominal pregnancy \| Delivery of viable fetus in abdominal pregnancy [ME04.Z] Ascites, unspecified Also known as: Ascites, unspecified \| Ascites \| abdominal dropsy \| hydrops abdominis \| ascites NOS [NB9Y] Other specified injuries to the abdomen, lower back, lumbar spine or pelvis Also known as: Other specified injuries to the abdomen, lower back, lumbar spine or pelvis \| Abdominal wall trauma \| Injury of pelvic floor \| pelvic floor blunt injury \| pelvic floor blunt trauma [5C75] Mixed disorder of acid-base balance Definition: This is a condition where more than one of the normal mechanisms that regulate the amount of acid or base content in the body are dysfunctional. Also known as: Mixed disorder of acid-base balance \| acid-base balance disturbance \| acid base balance abnormal \| acid-base balance disorder [NA02.1Z] Fracture of base of skull, unspecified Also known as: Fracture of base of skull, unspecified \| Fracture of base of skull \| basilar skull fracture [NA02.70] Fracture of condylar process of mandible Definition: Condylar process fractures are defined as fractures running above or posterior to a line confined by the sigmoid notch line and the masseteric notch line. The mandibular condylar process comprises three fracture levels and is subdivided into the head region, the condylar neck, and the condylar base. Fractures of the condylar head show typical fracture lines either within the lateral pole zone, which may lead to loss of vertical height, or medially to the pole zone, with the latter ones usually n Also known as: Fracture of condylar process of mandible \| Dislocation fracture of condylar process of mandible \| Displaced fracture of condylar process of mandible \| Undisplaced fracture of condylar process of mandible \| articular process fracture of the mandible Excludes: Fracture of ramus of mandible \| Fracture of subcondylar process of mandible [NC53.2] Fracture of first metacarpal bone Definition: A break in the first metacarpal bone, that which is part of the thumb. Also known as: Fracture of first metacarpal bone \| fracture of base of thumb \| fracture of first metacarpal \| Fracture of base of first metacarpal bone extending into joint \| Fracture of proximal end of first metacarpal bone extending into joint [NA02.1A] Other fractures of base of skull Also known as: Other fractures of base of skull \| Fracture of occiput without further specification \| occipital fracture \| Fracture of temporal bone without further specification \| styloid temporal bone fracture === GRAPH WALKS === --- Walk 1 --- [MD81.3] Acute abdomen Def: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases... --PARENT--> [MD81] Abdominal or pelvic pain Def: Pain, an unpleasant distress sensation occurring in varying degrees of severity, received by nerve ending in the abdominal and pelvic region.... --CHILD--> [MD81.2] Generalised abdominal pain Def: Pain, an unpleasant distress sensation occurring in varying degrees of severity, or cramps, spasmodic contraction causing severe pain in the abdominal area in general.... --- Walk 2 --- [MD81.3] Acute abdomen Def: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases... --PARENT--> [MD81] Abdominal or pelvic pain Def: Pain, an unpleasant distress sensation occurring in varying degrees of severity, received by nerve ending in the abdominal and pelvic region.... --EXCLUDES--> [?] Renal colic Def: A severe paroxysmal pain in the flank radiating to the groin, scrotum or labia, caused by blockage of the renal pelvis or ureter most commonly by a renal stone. May be associated with nausea and vomit... --- Walk 3 --- [JA01.0] Abdominal pregnancy Def: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy.... --EXCLUDES--> [?] Delivery of viable fetus in abdominal pregnancy Def: A condition caused by the development of a viable fetus to the culmination of the pregnancy period. This condition is characterised by parturition of a viable neonate from the abdominal cavity, at the... --PARENT--> [?] Other assisted single delivery --- Walk 4 --- [JA01.0] Abdominal pregnancy Def: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy.... --EXCLUDES--> [?] Delivery of viable fetus in abdominal pregnancy Def: A condition caused by the development of a viable fetus to the culmination of the pregnancy period. This condition is characterised by parturition of a viable neonate from the abdominal cavity, at the... --PARENT--> [?] Other assisted single delivery --- Walk 5 --- [ME04.Z] Ascites, unspecified --PARENT--> [ME04] Ascites Def: Accumulation or retention of free fluid in the abdominal peritoneal cavity between the tissues lining the abdomen and abdominal organs. The fluid may be serous, haemorrhagic, or the result of inflamma... --CHILD--> [ME04.Z] Ascites, unspecified --- Walk 6 --- [ME04.Z] Ascites, unspecified --PARENT--> [ME04] Ascites Def: Accumulation or retention of free fluid in the abdominal peritoneal cavity between the tissues lining the abdomen and abdominal organs. The fluid may be serous, haemorrhagic, or the result of inflamma... --CHILD--> [ME04.0] Fluid in peritoneal cavity	[ "[MD81.3] Acute abdomen\n Def: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases...\n --PARENT--> [MD81] Abdominal or pelvic pain\n Def: Pain, an unpleasant distress sensation occurring in varying degrees of severity, received by nerve ending in the abdominal and pelvic region....\n --CHILD--> [MD81.2] Generalised abdominal pain\n Def: Pain, an unpleasant distress sensation occurring in varying degrees of severity, or cramps, spasmodic contraction causing severe pain in the abdominal area in general....", "[MD81.3] Acute abdomen\n Def: A clinical syndrome with acute abdominal pain that is severe, and rapid onset. Acute abdomen may be caused by a variety of disorders, injuries, or diseases...\n --PARENT--> [MD81] Abdominal or pelvic pain\n Def: Pain, an unpleasant distress sensation occurring in varying degrees of severity, received by nerve ending in the abdominal and pelvic region....\n --EXCLUDES--> [?] Renal colic\n Def: A severe paroxysmal pain in the flank radiating to the groin, scrotum or labia, caused by blockage of the renal pelvis or ureter most commonly by a renal stone. May be associated with nausea and vomit...", "[JA01.0] Abdominal pregnancy\n Def: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy....\n --EXCLUDES--> [?] Delivery of viable fetus in abdominal pregnancy\n Def: A condition caused by the development of a viable fetus to the culmination of the pregnancy period. This condition is characterised by parturition of a viable neonate from the abdominal cavity, at the...\n --PARENT--> [?] Other assisted single delivery", "[JA01.0] Abdominal pregnancy\n Def: A condition characterised by implantation of the embryo within the peritoneal cavity during pregnancy....\n --EXCLUDES--> [?] Delivery of viable fetus in abdominal pregnancy\n Def: A condition caused by the development of a viable fetus to the culmination of the pregnancy period. This condition is characterised by parturition of a viable neonate from the abdominal cavity, at the...\n --PARENT--> [?] Other assisted single delivery", "[ME04.Z] Ascites, unspecified\n --PARENT--> [ME04] Ascites\n Def: Accumulation or retention of free fluid in the abdominal peritoneal cavity between the tissues lining the abdomen and abdominal organs. The fluid may be serous, haemorrhagic, or the result of inflamma...\n --CHILD--> [ME04.Z] Ascites, unspecified", "[ME04.Z] Ascites, unspecified\n --PARENT--> [ME04] Ascites\n Def: Accumulation or retention of free fluid in the abdominal peritoneal cavity between the tissues lining the abdomen and abdominal organs. The fluid may be serous, haemorrhagic, or the result of inflamma...\n --CHILD--> [ME04.0] Fluid in peritoneal cavity" ]	MD81.3	Acute abdomen	[ { "from_icd11": "MD81.3", "icd10_code": "R100", "icd10_title": "Acute abdomen" }, { "from_icd11": "JA01.0", "icd10_code": "O0000", "icd10_title": "Abdominal pregnancy without intrauterine pregnancy" }, { "from_icd11": "JA01.0", "icd10_code": "O000", "icd10_title": "Abdominal pregnancy" }, { "from_icd11": "ME04.Z", "icd10_code": "R180", "icd10_title": "Malignant ascites" }, { "from_icd11": "ME04.Z", "icd10_code": "R18", "icd10_title": "Ascites" }, { "from_icd11": "5C75", "icd10_code": "E874", "icd10_title": "Mixed disorder of acid-base balance" }, { "from_icd11": "NA02.1Z", "icd10_code": "S0219XA", "icd10_title": "Other fracture of base of skull, initial encounter for closed fracture" }, { "from_icd11": "NA02.1Z", "icd10_code": "S0211CA", "icd10_title": "Type II occipital condyle fracture, right side, initial encounter for closed fracture" }, { "from_icd11": "NA02.1Z", "icd10_code": "S0219XD", "icd10_title": "Other fracture of base of skull, subsequent encounter for fracture with routine healing" }, { "from_icd11": "NA02.1Z", "icd10_code": "S02119A", "icd10_title": "Unspecified fracture of occiput, initial encounter for closed fracture" }, { "from_icd11": "NA02.1Z", "icd10_code": "S02113A", "icd10_title": "Unspecified occipital condyle fracture, initial encounter for closed fracture" }, { "from_icd11": "NA02.1Z", "icd10_code": "S0211HA", "icd10_title": "Other fracture of occiput, left side, initial encounter for closed fracture" }, { "from_icd11": "NA02.1Z", "icd10_code": "S0211GA", "icd10_title": "Other fracture of occiput, right side, initial encounter for closed fracture" }, { "from_icd11": "NA02.1Z", "icd10_code": "S02119D", "icd10_title": "Unspecified fracture of occiput, subsequent encounter for fracture with routine healing" }, { "from_icd11": "NA02.1Z", "icd10_code": "S02118B", "icd10_title": "Other fracture of occiput, unspecified side, initial encounter for open fracture" } ]	R100	Acute abdomen
We reviewed the outside pathology slides obtained from the mass excision specimen. Scanning-power magnification revealed a solid tumor with lobulated contour . Low-power magnification showed a diffuse growth pattern without nested architecture or prominent vasculature . The solid areas were highly cellular and consisted of relatively uniform tumor cells. Mildly dilated, sinusoid-like vascular channels were occasionally noted in-between solid cellular sheets. High-power magnification depicted eosinophilic intracytoplasmic globules and ample granular cytoplasm . Most of the tumor cells had a centrally located, round nuclei showing mild pleomorphism and smooth nuclear membrane. Conspicuous nucleoli were rarely noted. In some areas, the discohesive tumor cells were arranged in a pseudoalveolar pattern . No LVSI, tumor cell necrosis, or mitosis was detected. No residual tumor was observed in the hysterectomy specimen. A 0.8 cm small fibrotic lesion identified in the cervix exhibited post-surgical inflammation and fibrosis caused by the previous mass excision. Regarding the morphological features and the patient’s age, we considered ASPS to be the most probable diagnosis. Similar to the case 1, the differential diagnosis included PEComa, metastatic RCC, and paraganglioma. We excluded CCS and granular cell tumor based on the outside pathology report stating negative immunoreactivities for desmin and S100.	4.070313	0.771973	sec[2]/sec[1]/sec[1]/p[0]	en	0.999998	PMC9139381	https://doi.org/10.3390/diagnostics12051102	[ "tumor", "power", "magnification", "solid", "cells", "outside", "pathology", "excision", "specimen", "pattern" ]	[ { "code": "2F9Z", "title": "Neoplasms of unknown behaviour of unspecified site" }, { "code": "ME61", "title": "Subcutaneous swelling, mass or lump of uncertain or unspecified nature" }, { "code": "2E6Z", "title": "Carcinoma in situ of unspecified site" }, { "code": "2F91.1", "title": "Neoplasms of unknown behaviour of trachea, bronchus or lung" }, { "code": "2F92", "title": "Neoplasms of unknown behaviour of skin" }, { "code": "PB6Y", "title": "Other unintentional cause of morbidity or mortality" }, { "code": "PA83.2&XE02T", "title": "Accidental contact with powered knife" }, { "code": "MA80.1", "title": "Dysphasia" }, { "code": "PA83.2", "title": "Unintentionally cut or pierced by other or unspecified sharp object" }, { "code": "PA83.2&XE8MJ", "title": "Accidental contact with powered chain-saw" } ]	=== ICD-11 CODES FOUND === [2F9Z] Neoplasms of unknown behaviour of unspecified site Also known as: Neoplasms of unknown behaviour of unspecified site \| neoplasia \| neoplasm growth NOS \| tumour of unspecified site \| tumourlet of unspecified site [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Definition: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature Also known as: Subcutaneous swelling, mass or lump of uncertain or unspecified nature \| localised swelling, mass or lump of skin and subcutaneous tissue \| localised subcutaneous nodules \| subcutaneous nodules \| superficial subcutaneous nodules Excludes: localized adiposity \| mass and lump: breast \| enlarged lymph nodes [2E6Z] Carcinoma in situ of unspecified site Also known as: Carcinoma in situ of unspecified site \| carcinoma in situ of unspecified site \| carcinoma in situ NOS \| carcinoma in situ \| in situ neoplasm [2F91.1] Neoplasms of unknown behaviour of trachea, bronchus or lung Also known as: Neoplasms of unknown behaviour of trachea, bronchus or lung \| trachea, bronchus or lung tumour NOS \| Intravascular bronchial alveolar tumour of unspecified site \| Bronchial adenoma of unknown behaviour of unspecified site \| Intravascular bronchial alveolar tumour unknown behaviour of unspecified site [2F92] Neoplasms of unknown behaviour of skin Also known as: Neoplasms of unknown behaviour of skin \| skin tumour NOS [PB6Y] Other unintentional cause of morbidity or mortality Also known as: Other unintentional cause of morbidity or mortality \| Exposure to other and unspecified man-made environmental factors \| Exposure to other specified factors \| Contact with agricultural machinery \| contact with animal-powered farm machine [MA80.1] Dysphasia Definition: A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. Also known as: Dysphasia \| loss of power of expression or comprehension \| Alalia \| Aphemia \| Semantic dysphasia Excludes: progressive isolated aphasia \| Developmental speech or language disorders [PA83.2] Unintentionally cut or pierced by other or unspecified sharp object Also known as: Unintentionally cut or pierced by other or unspecified sharp object \| Unintentionally cut or pierced by archery objects \| Contact with nonpowered hand tool \| Accidental contact with axe \| Accidental contact with can-opener === GRAPH WALKS === --- Walk 1 --- [2F9Z] Neoplasms of unknown behaviour of unspecified site --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues --RELATED_TO--> [?] Pathological fracture in neoplastic disease of unknown behaviour --- Walk 2 --- [2F9Z] Neoplasms of unknown behaviour of unspecified site --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues --RELATED_TO--> [?] Pathological fracture in neoplastic disease of unknown behaviour --- Walk 3 --- [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature... --EXCLUDES--> [?] Breast lump or mass female --PARENT--> [?] Symptoms, signs or clinical findings involving the female genital system --- Walk 4 --- [ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature... --EXCLUDES--> [?] Enlarged lymph nodes Def: Enlarged lymph node is called lymphadenopathy which means the abnormal enlargement of lymph nodes.... --EXCLUDES--> [?] Lymphadenitis --- Walk 5 --- [2E6Z] Carcinoma in situ of unspecified site --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues --CHILD--> [2E62] Carcinoma in situ of middle ear or respiratory system --- Walk 6 --- [2E6Z] Carcinoma in situ of unspecified site --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues --CHILD--> [2E60] Carcinoma in situ of oral cavity, oesophagus or stomach	[ "[2F9Z] Neoplasms of unknown behaviour of unspecified site\n --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues\n --RELATED_TO--> [?] Pathological fracture in neoplastic disease of unknown behaviour", "[2F9Z] Neoplasms of unknown behaviour of unspecified site\n --PARENT--> [?] Neoplasms of unknown behaviour, except of lymphoid, haematopoietic, central nervous system or related tissues\n --RELATED_TO--> [?] Pathological fracture in neoplastic disease of unknown behaviour", "[ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature\n Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature...\n --EXCLUDES--> [?] Breast lump or mass female\n --PARENT--> [?] Symptoms, signs or clinical findings involving the female genital system", "[ME61] Subcutaneous swelling, mass or lump of uncertain or unspecified nature\n Def: One or more localised subcutaneous soft tissue masses of undetermined or unspecified nature...\n --EXCLUDES--> [?] Enlarged lymph nodes\n Def: Enlarged lymph node is called lymphadenopathy which means the abnormal enlargement of lymph nodes....\n --EXCLUDES--> [?] Lymphadenitis", "[2E6Z] Carcinoma in situ of unspecified site\n --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues\n --CHILD--> [2E62] Carcinoma in situ of middle ear or respiratory system", "[2E6Z] Carcinoma in situ of unspecified site\n --PARENT--> [?] In situ neoplasms, except of lymphoid, haematopoietic, central nervous system or related tissues\n --CHILD--> [2E60] Carcinoma in situ of oral cavity, oesophagus or stomach" ]	2F9Z	Neoplasms of unknown behaviour of unspecified site	[ { "from_icd11": "2F9Z", "icd10_code": "D487", "icd10_title": "Neoplasm of uncertain behavior of other specified sites" }, { "from_icd11": "2F9Z", "icd10_code": "D482", "icd10_title": "Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system" }, { "from_icd11": "2F9Z", "icd10_code": "D37-D48", "icd10_title": "" }, { "from_icd11": "2F9Z", "icd10_code": "D377", "icd10_title": "" }, { "from_icd11": "2F9Z", "icd10_code": "D48", "icd10_title": "Neoplasm of uncertain behavior of other and unspecified sites" }, { "from_icd11": "2F9Z", "icd10_code": "D489", "icd10_title": "Neoplasm of uncertain behavior, unspecified" }, { "from_icd11": "ME61", "icd10_code": "R2240", "icd10_title": "Localized swelling, mass and lump, unspecified lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2232", "icd10_title": "Localized swelling, mass and lump, left upper limb" }, { "from_icd11": "ME61", "icd10_code": "R2242", "icd10_title": "Localized swelling, mass and lump, left lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2231", "icd10_title": "Localized swelling, mass and lump, right upper limb" }, { "from_icd11": "ME61", "icd10_code": "R2241", "icd10_title": "Localized swelling, mass and lump, right lower limb" }, { "from_icd11": "ME61", "icd10_code": "R2233", "icd10_title": "Localized swelling, mass and lump, upper limb, bilateral" }, { "from_icd11": "ME61", "icd10_code": "R2243", "icd10_title": "Localized swelling, mass and lump, lower limb, bilateral" }, { "from_icd11": "ME61", "icd10_code": "R2230", "icd10_title": "Localized swelling, mass and lump, unspecified upper limb" }, { "from_icd11": "ME61", "icd10_code": "R220", "icd10_title": "Localized swelling, mass and lump, head" } ]	D487	Neoplasm of uncertain behavior of other specified sites
Methotrexate (MTX) is an immunosuppressive drug that is commonly utilised for various autoimmune diseases such as rheumatoid arthritis (RA). However, MTX is associated with increased risk for lymphoproliferative disorders or lymphomas. 1 Epstein‐Barr virus‐positive mucocutaneous ulcer (EBVMCU) was first reported in 2010 2 and was designated as a provisional entity in the 2017 World Health Organization classification for lymphoid neoplasms 3 with MTX as one of the leading cause. 4 Currently, EBVMCU is considered as a spectrum of B‐cell lymphoproliferative diseases. Epstein‐Barr virus‐positive mucocutaneous ulcer commonly manifests as sharply circumscribed mucocutaneous ulcers. 2 Notably, most cases occur on mucosal surfaces with only 10% of reported cases (10/100) manifesting in the skin. 4 Epstein‐Barr virus‐positive mucocutaneous ulcer lesions contain varying numbers of cells with Hodgkin and Reed‐Sternberg cells‐like morphology, but the clinical course of EBVMCU is benign and must be distinguished from lymphomas. 2 Alleviation of immunosuppression can lead to spontaneous regression of EBVMCU 4 but how this course correlates with local or systemic EBV activation has not been described. Herein, we report a case of MTX‐associated EBVMCU of the lower leg that underwent spontaneous regression after MTX withdrawal, during which negative conversion of local but not systemic EBV activation was confirmed.	4.375	0.793945	sec[1]/p[0]	en	0.999998	PMC9168019	https://doi.org/10.1002/ski2.108	[ "ebvmcu", "mucocutaneous", "epstein", "barr", "virus", "ulcer", "that", "commonly", "diseases", "associated" ]	[ { "code": "LC51", "title": "Developmental venous malformations involving the skin" }, { "code": "4A62", "title": "Behçet disease" }, { "code": "EC92", "title": "Mucocutaneous or cutaneous pain syndromes" }, { "code": "1F23.14", "title": "Chronic mucocutaneous candidosis" }, { "code": "EE8Y", "title": "Other specified histiocytic-granulomatous disorders of the skin" }, { "code": "3B64.01", "title": "Hereditary thrombocytopenia" }, { "code": "KC23", "title": "Neonatal disorders of the oral mucosa" }, { "code": "GB41", "title": "Nephrotic syndrome" }, { "code": "1D81.0", "title": "Mononucleosis due to Epstein-Barr virus" }, { "code": "4A01.22", "title": "Immune dysregulation syndromes presenting primarily with lymphoproliferation" } ]	=== ICD-11 CODES FOUND === [LC51] Developmental venous malformations involving the skin Definition: Certain genetically-determined syndromes presenting with venous anomalies in the skin Also known as: Developmental venous malformations involving the skin \| Blue rubber bleb naevus syndrome \| Bean syndrome (MIM 112200) \| Mucocutaneous venous malformations \| Glomuvenous malformation [4A62] Behçet disease Definition: Behçet disease is a disease of incompletely understood aetiopathogenesis characterised by recurrent oral and/or genital aphthous ulcers accompanied by cutaneous, ocular, articular, gastrointestinal, and/or central nervous system inflammatory lesions. Small vessel vasculitis, thrombotic vasculopathy, arteritis and arterial aneurysms may occur. It has a high prevalence from the Eastern Mediterranean across Central Asia to China and Japan. Also known as: Behçet disease \| Adamantiades-Behçet disease \| Mucocutaneous Behçet disease \| Oropharyngeal ulceration due to Behçet disease \| Anogenital ulceration due to Behçet disease Includes: Adamantiades-Behçet disease [EC92] Mucocutaneous or cutaneous pain syndromes Definition: A range of chronic focal pain disorders affecting skin or mucosal sites, with a predilection for the orocervical and urogenital regions. They are diagnoses of exclusion and should be made only when no other explanation for the symptoms can be found. They are frequently associated with severe psychological distress. Also known as: Mucocutaneous or cutaneous pain syndromes [1F23.14] Chronic mucocutaneous candidosis Definition: Chronic Mucocutaneous Candidiasis is a primary immune deficiency characterised by persistent and/or recurrent infections of skin, nails and mucous membranes, caused by organisms of the genus Candida, mainly C. albicans. Also known as: Chronic mucocutaneous candidosis \| Chronic mucocutaneous candidiasis \| candida granuloma \| mucocutaneous candidiasis \| candidiasis granuloma [EE8Y] Other specified histiocytic-granulomatous disorders of the skin Also known as: Other specified histiocytic-granulomatous disorders of the skin \| Cutaneous or mucocutaneous Crohn disease \| Cutaneous Crohn disease \| Parastomal Crohn disease \| Metastatic cutaneous Crohn disease [3B64.01] Hereditary thrombocytopenia Definition: A disease caused by a genetically inherited mutation leading to decreased platelet count. This disease is characterised by decreased levels of platelets within the blood. This disease may present with increased bruising or haemorrhaging. Confirmation is by identification of decreased platelet count in a blood sample. Also known as: Hereditary thrombocytopenia \| Congenital amegakaryocytic thrombocytopenia \| MYH9 macrothrombocytopenia syndromes \| MYH9-related disease \| May-Hegglin thrombocytopenia [KC23] Neonatal disorders of the oral mucosa Also known as: Neonatal disorders of the oral mucosa \| Neonatal oral mucosal inclusion cyst \| Epstein pearl \| Epstein's pearl \| Bohn nodules [GB41] Nephrotic syndrome Definition: A condition characterised by severe proteinuria, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in hypoalbuminaemia and generalised oedema. There is also usually hyperlipidaemia. Other manifestations of glomerular disease may be present. There are many possible causes and renal histological appearances. Possible complications include vascular thrombosis, infections, malnutrition and renal failure. Also known as: Nephrotic syndrome \| NS - [nephrotic syndrome] \| nephrosis syndrome \| nephrosis NOS \| glomerular lesion nephrosis [1D81.0] Mononucleosis due to Epstein-Barr virus Definition: A disease typically caused by an infection with Epstein-Barr virus (EBV). This disease commonly presents with extreme fatigue, fever, acute pharyngitis, body aches, or lymphadenopathy. Transmission is by direct contact with infected body fluids, commonly through saliva. Also known as: Mononucleosis due to Epstein-Barr virus \| infectious adenitis \| Pfeiffer disease \| EBV - [Epstein-Barr virus] infection NOS \| Epstein-Barr virus infection NOS [4A01.22] Immune dysregulation syndromes presenting primarily with lymphoproliferation Also known as: Immune dysregulation syndromes presenting primarily with lymphoproliferation \| Autosomal recessive lymphoproliferative disease \| Autoimmune lymphoproliferative syndrome \| autoimmune lymphoproliferative syndrome with recurrent infections \| Canale-Smith syndrome === GRAPH WALKS === --- Walk 1 --- [LC51] Developmental venous malformations involving the skin Def: Certain genetically-determined syndromes presenting with venous anomalies in the skin... --PARENT--> [?] Developmental anomalies of cutaneous vasculature Def: Congenital vascular malformations affecting the skin... --CHILD--> [LC52] Complex or combined developmental vascular malformations involving the skin --- Walk 2 --- [LC51] Developmental venous malformations involving the skin Def: Certain genetically-determined syndromes presenting with venous anomalies in the skin... --PARENT--> [?] Developmental anomalies of cutaneous vasculature Def: Congenital vascular malformations affecting the skin... --CHILD--> [LC50] Developmental capillary vascular malformations of the skin --- Walk 3 --- [4A62] Behçet disease Def: Behçet disease is a disease of incompletely understood aetiopathogenesis characterised by recurrent oral and/or genital aphthous ulcers accompanied by cutaneous, ocular, articular, gastrointestinal, a... --RELATED_TO--> [?] Transient neonatal Behçet disease Def: An uncommon disorder in which the newborn infants of mothers with Behçet disease develop a transient form of the disease with cutaneous pustules and oral and genital ulcers. Although the disease does ... --PARENT--> [?] Behçet disease Def: Behçet disease is a disease of incompletely understood aetiopathogenesis characterised by recurrent oral and/or genital aphthous ulcers accompanied by cutaneous, ocular, articular, gastrointestinal, a... --- Walk 4 --- [4A62] Behçet disease Def: Behçet disease is a disease of incompletely understood aetiopathogenesis characterised by recurrent oral and/or genital aphthous ulcers accompanied by cutaneous, ocular, articular, gastrointestinal, a... --RELATED_TO--> [?] Transient neonatal Behçet disease Def: An uncommon disorder in which the newborn infants of mothers with Behçet disease develop a transient form of the disease with cutaneous pustules and oral and genital ulcers. Although the disease does ... --PARENT--> [?] Behçet disease Def: Behçet disease is a disease of incompletely understood aetiopathogenesis characterised by recurrent oral and/or genital aphthous ulcers accompanied by cutaneous, ocular, articular, gastrointestinal, a... --- Walk 5 --- [EC92] Mucocutaneous or cutaneous pain syndromes Def: A range of chronic focal pain disorders affecting skin or mucosal sites, with a predilection for the orocervical and urogenital regions. They are diagnoses of exclusion and should be made only when no... --RELATED_TO--> [?] Burning mouth syndrome Def: Chronic burning mouth pain is chronic orofacial pain with an intraoral burning or dysaesthetic sensation that recurs for more than two hours per day on 50 % of the days over more than three months, wi... --CHILD--> [?] Cheilodynia Def: This is a diagnosis of exclusion where no alternative cause for a persistent unpleasant burning sensation affecting the lips can be found. It is regarded as a form of burning mouth syndrome.... --- Walk 6 --- [EC92] Mucocutaneous or cutaneous pain syndromes Def: A range of chronic focal pain disorders affecting skin or mucosal sites, with a predilection for the orocervical and urogenital regions. They are diagnoses of exclusion and should be made only when no... --CHILD--> [EC92.0] Penoscrotodynia Def: An uncommon but distressing somatoform disorder affecting men in which there is a clear and precise complaint of genital pain and/or a skin burning sensation for which no underlying cause can be found... --PARENT--> [EC92] Mucocutaneous or cutaneous pain syndromes Def: A range of chronic focal pain disorders affecting skin or mucosal sites, with a predilection for the orocervical and urogenital regions. They are diagnoses of exclusion and should be made only when no...	[ "[LC51] Developmental venous malformations involving the skin\n Def: Certain genetically-determined syndromes presenting with venous anomalies in the skin...\n --PARENT--> [?] Developmental anomalies of cutaneous vasculature\n Def: Congenital vascular malformations affecting the skin...\n --CHILD--> [LC52] Complex or combined developmental vascular malformations involving the skin", "[LC51] Developmental venous malformations involving the skin\n Def: Certain genetically-determined syndromes presenting with venous anomalies in the skin...\n --PARENT--> [?] Developmental anomalies of cutaneous vasculature\n Def: Congenital vascular malformations affecting the skin...\n --CHILD--> [LC50] Developmental capillary vascular malformations of the skin", "[4A62] Behçet disease\n Def: Behçet disease is a disease of incompletely understood aetiopathogenesis characterised by recurrent oral and/or genital aphthous ulcers accompanied by cutaneous, ocular, articular, gastrointestinal, a...\n --RELATED_TO--> [?] Transient neonatal Behçet disease\n Def: An uncommon disorder in which the newborn infants of mothers with Behçet disease develop a transient form of the disease with cutaneous pustules and oral and genital ulcers. Although the disease does ...\n --PARENT--> [?] Behçet disease\n Def: Behçet disease is a disease of incompletely understood aetiopathogenesis characterised by recurrent oral and/or genital aphthous ulcers accompanied by cutaneous, ocular, articular, gastrointestinal, a...", "[4A62] Behçet disease\n Def: Behçet disease is a disease of incompletely understood aetiopathogenesis characterised by recurrent oral and/or genital aphthous ulcers accompanied by cutaneous, ocular, articular, gastrointestinal, a...\n --RELATED_TO--> [?] Transient neonatal Behçet disease\n Def: An uncommon disorder in which the newborn infants of mothers with Behçet disease develop a transient form of the disease with cutaneous pustules and oral and genital ulcers. Although the disease does ...\n --PARENT--> [?] Behçet disease\n Def: Behçet disease is a disease of incompletely understood aetiopathogenesis characterised by recurrent oral and/or genital aphthous ulcers accompanied by cutaneous, ocular, articular, gastrointestinal, a...", "[EC92] Mucocutaneous or cutaneous pain syndromes\n Def: A range of chronic focal pain disorders affecting skin or mucosal sites, with a predilection for the orocervical and urogenital regions. They are diagnoses of exclusion and should be made only when no...\n --RELATED_TO--> [?] Burning mouth syndrome\n Def: Chronic burning mouth pain is chronic orofacial pain with an intraoral burning or dysaesthetic sensation that recurs for more than two hours per day on 50 % of the days over more than three months, wi...\n --CHILD--> [?] Cheilodynia\n Def: This is a diagnosis of exclusion where no alternative cause for a persistent unpleasant burning sensation affecting the lips can be found. It is regarded as a form of burning mouth syndrome....", "[EC92] Mucocutaneous or cutaneous pain syndromes\n Def: A range of chronic focal pain disorders affecting skin or mucosal sites, with a predilection for the orocervical and urogenital regions. They are diagnoses of exclusion and should be made only when no...\n --CHILD--> [EC92.0] Penoscrotodynia\n Def: An uncommon but distressing somatoform disorder affecting men in which there is a clear and precise complaint of genital pain and/or a skin burning sensation for which no underlying cause can be found...\n --PARENT--> [EC92] Mucocutaneous or cutaneous pain syndromes\n Def: A range of chronic focal pain disorders affecting skin or mucosal sites, with a predilection for the orocervical and urogenital regions. They are diagnoses of exclusion and should be made only when no..." ]	LC51	Developmental venous malformations involving the skin	[ { "from_icd11": "LC51", "icd10_code": "Q278", "icd10_title": "Other specified congenital malformations of peripheral vascular system" }, { "from_icd11": "4A62", "icd10_code": "M352", "icd10_title": "Behcet's disease" }, { "from_icd11": "4A62", "icd10_code": "M35", "icd10_title": "Other systemic involvement of connective tissue" }, { "from_icd11": "KC23", "icd10_code": "K1379", "icd10_title": "Other lesions of oral mucosa" }, { "from_icd11": "KC23", "icd10_code": "K1370", "icd10_title": "Unspecified lesions of oral mucosa" }, { "from_icd11": "KC23", "icd10_code": "K137", "icd10_title": "Other and unspecified lesions of oral mucosa" }, { "from_icd11": "GB41", "icd10_code": "N049", "icd10_title": "Nephrotic syndrome with unspecified morphologic changes" }, { "from_icd11": "GB41", "icd10_code": "N041", "icd10_title": "Nephrotic syndrome with focal and segmental glomerular lesions" }, { "from_icd11": "GB41", "icd10_code": "N042", "icd10_title": "Nephrotic syndrome with diffuse membranous glomerulonephritis" }, { "from_icd11": "GB41", "icd10_code": "N040", "icd10_title": "Nephrotic syndrome with minor glomerular abnormality" }, { "from_icd11": "GB41", "icd10_code": "N048", "icd10_title": "Nephrotic syndrome with other morphologic changes" }, { "from_icd11": "GB41", "icd10_code": "N045", "icd10_title": "Nephrotic syndrome with diffuse mesangiocapillary glomerulonephritis" }, { "from_icd11": "GB41", "icd10_code": "N044", "icd10_title": "Nephrotic syndrome with diffuse endocapillary proliferative glomerulonephritis" }, { "from_icd11": "GB41", "icd10_code": "N043", "icd10_title": "Nephrotic syndrome with diffuse mesangial proliferative glomerulonephritis" }, { "from_icd11": "GB41", "icd10_code": "N04", "icd10_title": "Nephrotic syndrome" } ]	Q278	Other specified congenital malformations of peripheral vascular system
The twelve-derivation electrocardiogram was unremarkable. No coronary stenosis or dissection was found by coronary computed tomographic angiography. Transthoracic echocardiography performed at day 1 after transfer to the nephrology intensive care unit (i.e., at day 3 post-delivery) revealed hyperechogenicity, ballooning and akinesia of the basal and mid segments of the inferoseptal ( Supplementary Video 1 ), inferior ( Supplementary Video 2 ) and anteroseptal ( Supplementary Video 3 ) walls, with mild impairment of left ventricular ejection function (LVEF, 45%), suggesting inverted Takotsubo syndrome, a rare variant of this disease that presents with basal ballooning instead of apical ballooning. Cardiac MRI performed at day 3 after transfer to the nephrology intensive care unit (i.e., at day 5 post-delivery) revealed a non-dilated, non-hypertrophied left ventricle, slightly altered global LVEF (51%) and characteristic wall motion abnormalities of inverted Takostubo syndrome including hypokinesia of the basal third predominating over the septum and apical hyperkinesia ( Supplementary Video 4 ) associated with diffuse basal myocardial edema detected by T2 mapping sequence without late gadolinium enhancement . Global T2 mapping values demonstrated a gradient from the base to the apex of the left ventricle: 56 ± 4 ms in the first third, 51 ± 7 ms in the second third, and 48 ± 3 ms at the apical level.	4.144531	0.637695	sec[2]/p[3]	en	0.999997	PMC9008274	https://doi.org/10.3389/fcvm.2022.832098	[ "basal", "supplementary", "video", "ballooning", "apical", "coronary", "transfer", "nephrology", "intensive", "unit" ]	[ { "code": "EC30", "title": "Epidermolysis bullosa simplex" }, { "code": "8A00.1Y", "title": "Other specified atypical parkinsonism" }, { "code": "2F72.Y", "title": "Other specified neoplasms of uncertain behaviour of skin" }, { "code": "MG72", "title": "Abnormal results of function studies of other organs and systems" }, { "code": "2C32.Z", "title": "Basal cell carcinoma of skin, unspecified" }, { "code": "LA30.3", "title": "Hyperdontia" }, { "code": "6C51.Z", "title": "Gaming disorder, unspecified" }, { "code": "BC43.5", "title": "Stress-induced cardiomyopathy" }, { "code": "BB62.Z", "title": "Mitral valve prolapse, unspecified" }, { "code": "PA50.Z&XE3J3", "title": "Balloon accident injuring occupant" } ]	=== ICD-11 CODES FOUND === [EC30] Epidermolysis bullosa simplex Definition: Epidermolysis bullosa simplex is the name given to a heterogeneous group of genetically-determined defects in epidermal cell-cell adhesion. These give rise to blistering in response to frictional and shearing stresses. Also known as: Epidermolysis bullosa simplex \| Epidermolytic epidermolysis bullosa \| Suprabasal epidermolysis bullosa simplex \| Suprabasal EBS \| Acantholytic epidermolysis bullosa [8A00.1Y] Other specified atypical parkinsonism Also known as: Other specified atypical parkinsonism \| Corticobasal degeneration \| CBD - [corticobasal degeneration] \| Calcification of basal ganglia \| Olivopontocerebellar atrophy [2F72.Y] Other specified neoplasms of uncertain behaviour of skin Also known as: Other specified neoplasms of uncertain behaviour of skin \| Atypical fibroxanthoma \| Kaposiform haemangioendothelioma \| Basal cell tumour of unspecified site \| Composite haemangioendothelioma of unspecified site [MG72] Abnormal results of function studies of other organs and systems Also known as: Abnormal results of function studies of other organs and systems \| Abnormal basal metabolic rate \| Abnormal BMR - [basal metabolic rate] \| High basal metabolic rate \| Low basal metabolic rate [2C32.Z] Basal cell carcinoma of skin, unspecified Also known as: Basal cell carcinoma of skin, unspecified \| Basal cell carcinoma of skin \| Basalioma \| Basal cell epithelioma of skin \| BCC - [basal cell carcinoma] of skin [LA30.3] Hyperdontia Definition: Hyperdontia is the condition of having supernumerary teeth, or teeth which appear in addition to the regular number of teeth. Also known as: Hyperdontia \| Supplementary teeth \| Supernumerary teeth \| supernumerary tooth \| supplemental teeth Includes: Supplementary teeth \| Supernumerary teeth \| distomolar [6C51.Z] Gaming disorder, unspecified Also known as: Gaming disorder, unspecified \| Gaming disorder \| Digital gaming disorder \| Video gaming disorder [BC43.5] Stress-induced cardiomyopathy Definition: Stress-induced or Takotsubo cardiomyopathy is a disease of the myocardium characterised by episodes of acute onset, reversible left ventricular apical wall motion abnormalities mimicking acute myocardial infarction, but with non-specific electrocardiographic ST elevation and T wave changes, and minimal myocardial enzymatic release, in the absence of coronary stenosis. Also known as: Stress-induced cardiomyopathy \| Takotsubo cardiomyopathy \| stress cardiomyopathy \| broken heart syndrome \| apical ballooning syndrome Includes: Takotsubo cardiomyopathy [BB62.Z] Mitral valve prolapse, unspecified Also known as: Mitral valve prolapse, unspecified \| Mitral valve prolapse \| systolic click-murmur syndrome \| ballooning mitral valve \| Barlow syndrome === GRAPH WALKS === --- Walk 1 --- [EC30] Epidermolysis bullosa simplex Def: Epidermolysis bullosa simplex is the name given to a heterogeneous group of genetically-determined defects in epidermal cell-cell adhesion. These give rise to blistering in response to frictional and ... --PARENT--> [?] Genetically-determined epidermolysis bullosa Def: Epidermolysis bullosa (EB) is the name given to a heterogeneous group of blistering disorders which in the majority of cases are due to genetically-determined defects in structural proteins of the epi... --CHILD--> [EC30] Epidermolysis bullosa simplex Def: Epidermolysis bullosa simplex is the name given to a heterogeneous group of genetically-determined defects in epidermal cell-cell adhesion. These give rise to blistering in response to frictional and ... --- Walk 2 --- [EC30] Epidermolysis bullosa simplex Def: Epidermolysis bullosa simplex is the name given to a heterogeneous group of genetically-determined defects in epidermal cell-cell adhesion. These give rise to blistering in response to frictional and ... --PARENT--> [?] Genetically-determined epidermolysis bullosa Def: Epidermolysis bullosa (EB) is the name given to a heterogeneous group of blistering disorders which in the majority of cases are due to genetically-determined defects in structural proteins of the epi... --EXCLUDES--> [?] Epidermolysis bullosa acquisita Def: Epidermolysis bullosa acquisita is an acquired non-familial blistering disease characterised by the presence of autoantibodies to collagen VII at the epidermal basement membrane zone, as demonstrated ... --- Walk 3 --- [8A00.1Y] Other specified atypical parkinsonism --PARENT--> [8A00.1] Atypical parkinsonism Def: Atypical parkinsonism is a term used to describe several neurodegenerative conditions where the degeneration extends beyond the substantia nigra and is more extensive than seen in conditions like Park... --RELATED_TO--> [?] Lewy body disease Def: Lewy body disease is a neurodegenerative disorder and the second most common form of dementia in the elderly after Alzheimer disease. Lewy bodies are histologically defined as intracytoplasmic eosinop... --- Walk 4 --- [8A00.1Y] Other specified atypical parkinsonism --PARENT--> [8A00.1] Atypical parkinsonism Def: Atypical parkinsonism is a term used to describe several neurodegenerative conditions where the degeneration extends beyond the substantia nigra and is more extensive than seen in conditions like Park... --RELATED_TO--> [?] Multiple system atrophy, Parkinsonism Def: This is a progressive disorder of the central and autonomic nervous systems, characterised by orthostatic hypotension (an excessive drop in blood pressure when standing up), which causes dizziness or ... --- Walk 5 --- [2F72.Y] Other specified neoplasms of uncertain behaviour of skin --PARENT--> [2F72] Neoplasms of uncertain behaviour of skin --CHILD--> [2F72.Y] Other specified neoplasms of uncertain behaviour of skin --- Walk 6 --- [2F72.Y] Other specified neoplasms of uncertain behaviour of skin --PARENT--> [2F72] Neoplasms of uncertain behaviour of skin --CHILD--> [2F72.2] Melanocytic naevus with severe melanocytic dysplasia Def: Melanocytic naevus with severe melanocytic dysplasia is a histopathological diagnosis based on the presence of severe cytological atypia, defined as enlarged, spindle- and epithelioid-shaped melanocyt...	[ "[EC30] Epidermolysis bullosa simplex\n Def: Epidermolysis bullosa simplex is the name given to a heterogeneous group of genetically-determined defects in epidermal cell-cell adhesion. These give rise to blistering in response to frictional and ...\n --PARENT--> [?] Genetically-determined epidermolysis bullosa\n Def: Epidermolysis bullosa (EB) is the name given to a heterogeneous group of blistering disorders which in the majority of cases are due to genetically-determined defects in structural proteins of the epi...\n --CHILD--> [EC30] Epidermolysis bullosa simplex\n Def: Epidermolysis bullosa simplex is the name given to a heterogeneous group of genetically-determined defects in epidermal cell-cell adhesion. These give rise to blistering in response to frictional and ...", "[EC30] Epidermolysis bullosa simplex\n Def: Epidermolysis bullosa simplex is the name given to a heterogeneous group of genetically-determined defects in epidermal cell-cell adhesion. These give rise to blistering in response to frictional and ...\n --PARENT--> [?] Genetically-determined epidermolysis bullosa\n Def: Epidermolysis bullosa (EB) is the name given to a heterogeneous group of blistering disorders which in the majority of cases are due to genetically-determined defects in structural proteins of the epi...\n --EXCLUDES--> [?] Epidermolysis bullosa acquisita\n Def: Epidermolysis bullosa acquisita is an acquired non-familial blistering disease characterised by the presence of autoantibodies to collagen VII at the epidermal basement membrane zone, as demonstrated ...", "[8A00.1Y] Other specified atypical parkinsonism\n --PARENT--> [8A00.1] Atypical parkinsonism\n Def: Atypical parkinsonism is a term used to describe several neurodegenerative conditions where the degeneration extends beyond the substantia nigra and is more extensive than seen in conditions like Park...\n --RELATED_TO--> [?] Lewy body disease\n Def: Lewy body disease is a neurodegenerative disorder and the second most common form of dementia in the elderly after Alzheimer disease. Lewy bodies are histologically defined as intracytoplasmic eosinop...", "[8A00.1Y] Other specified atypical parkinsonism\n --PARENT--> [8A00.1] Atypical parkinsonism\n Def: Atypical parkinsonism is a term used to describe several neurodegenerative conditions where the degeneration extends beyond the substantia nigra and is more extensive than seen in conditions like Park...\n --RELATED_TO--> [?] Multiple system atrophy, Parkinsonism\n Def: This is a progressive disorder of the central and autonomic nervous systems, characterised by orthostatic hypotension (an excessive drop in blood pressure when standing up), which causes dizziness or ...", "[2F72.Y] Other specified neoplasms of uncertain behaviour of skin\n --PARENT--> [2F72] Neoplasms of uncertain behaviour of skin\n --CHILD--> [2F72.Y] Other specified neoplasms of uncertain behaviour of skin", "[2F72.Y] Other specified neoplasms of uncertain behaviour of skin\n --PARENT--> [2F72] Neoplasms of uncertain behaviour of skin\n --CHILD--> [2F72.2] Melanocytic naevus with severe melanocytic dysplasia\n Def: Melanocytic naevus with severe melanocytic dysplasia is a histopathological diagnosis based on the presence of severe cytological atypia, defined as enlarged, spindle- and epithelioid-shaped melanocyt..." ]	EC30	Epidermolysis bullosa simplex	[ { "from_icd11": "EC30", "icd10_code": "Q810", "icd10_title": "Epidermolysis bullosa simplex" }, { "from_icd11": "2F72.Y", "icd10_code": "D485", "icd10_title": "Neoplasm of uncertain behavior of skin" }, { "from_icd11": "MG72", "icd10_code": "R948", "icd10_title": "Abnormal results of function studies of other organs and systems" }, { "from_icd11": "2C32.Z", "icd10_code": "C44319", "icd10_title": "Basal cell carcinoma of skin of other parts of face" }, { "from_icd11": "2C32.Z", "icd10_code": "C44", "icd10_title": "Other and unspecified malignant neoplasm of skin" }, { "from_icd11": "LA30.3", "icd10_code": "K001", "icd10_title": "Supernumerary teeth" }, { "from_icd11": "6C51.Z", "icd10_code": "F6381", "icd10_title": "Intermittent explosive disorder" }, { "from_icd11": "6C51.Z", "icd10_code": "F6389", "icd10_title": "Other impulse disorders" }, { "from_icd11": "6C51.Z", "icd10_code": "F638", "icd10_title": "Other impulse disorders" }, { "from_icd11": "BB62.Z", "icd10_code": "I341", "icd10_title": "Nonrheumatic mitral (valve) prolapse" }, { "from_icd11": "PA50.Z&XE3J3", "icd10_code": "V960", "icd10_title": "Balloon accident injuring occupant" } ]	Q810	Epidermolysis bullosa simplex
There are no current guidelines for the selection of antibiotic agents, concentration, or injection volume for such unconventional treatment. We chose the nonpreserved preparations of moxifloxacin and cefuroxime, at higher concentrations than previously reported . The concentrations were chosen because they have been routinely used for intracameral injection in cataract surgeries world-wide . We limited the delivered volume of the antibiotics (only 0.06 mL of cefuroxime was injected) to avoid a Descemet's membrane detachment from the significant stromal edema created by the injections. We also aimed to place our needle-tracks outside of the visual-axis. Within one to two days after each intrastromal injection, the patient was able to resume wear of his scleral lens, which provided him with essential surface protection and sharper vision. Merely two weeks after the second injection, the patient regained 20/40 vision in his scleral lens, which would have been impossible had he undergone a repeat PK. To date, more than two years after the intrastromal injections, there were no signs of endothelial dysfunction or other signs of corneal toxicity. Our case indicated the more concentrated stromal injections were well tolerated by the endothelium of a corneal graft. The prominence of the needle-tracks has reduced with time, and while they are not affecting his vision, they are still visible on examination.	4.03125	0.893066	sec[2]/p[8]	en	0.999998	PMC9729021	https://doi.org/10.1155/2022/5830617	[ "injection", "they", "injections", "vision", "cefuroxime", "concentrations", "stromal", "needle", "tracks", "intrastromal" ]	[ { "code": "PL11.2Z", "title": "Embolisation, as mode of injury or harm, unspecified" }, { "code": "QA50", "title": "Embolisation without injury or harm" }, { "code": "EL73.2", "title": "Adverse reaction to injection of neurotoxin" }, { "code": "EL73.0", "title": "Adverse reaction to dermal or deep fillers" }, { "code": "ED6Y", "title": "Other specified disorders of skin pigmentation" }, { "code": "9E1Z", "title": "Diseases of the visual system, unspecified" }, { "code": "MC1Y", "title": "Other specified symptoms or signs involving the visual system" }, { "code": "9D9Z", "title": "Vision impairment, unspecified" }, { "code": "9D90.2", "title": "Moderate vision impairment" }, { "code": "QA00.6Z", "title": "Examination of eyes or vision, unspecified" } ]	=== ICD-11 CODES FOUND === [PL11.2Z] Embolisation, as mode of injury or harm, unspecified Also known as: Embolisation, as mode of injury or harm, unspecified \| Embolisation, as mode of injury or harm \| embolic phenomenon as mode of injury \| embolism due to intervention \| injection of air as mode of injury [QA50] Embolisation without injury or harm Definition: An embolisation without documented injury or harm occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there. Also known as: Embolisation without injury or harm \| Embolic phenomenon without documented injury or harm \| Air embolism without documented injury or harm \| Injection of air without injury or harm Excludes: Embolisation, as mode of injury or harm [EL73.2] Adverse reaction to injection of neurotoxin Definition: Adverse event resulting from use of neurotoxins, especially botulinum toxin, into the skin. This is most commonly administered for aesthetic reasons. Recognised problems include ptosis, diplopia and hypersensitivity to the toxin. Details of the reaction should be coded separately. Also known as: Adverse reaction to injection of neurotoxin \| Adverse reaction to injection of botulinum toxin [EL73.0] Adverse reaction to dermal or deep fillers Definition: Any adverse event attributable to the use of injected fillers used for soft tissue augmentation. Also known as: Adverse reaction to dermal or deep fillers \| Cutaneous necrosis following injection of filler \| Foreign body granulomatous reaction to injected filler \| Nodule formation attributable to injected filler \| Serious adverse reaction to injection of filler Excludes: Pyogenic abscess of the skin [ED6Y] Other specified disorders of skin pigmentation Also known as: Other specified disorders of skin pigmentation \| Non-melanin pigmentation due to ingested or injected substance \| Carotenoderma \| Argyria \| Chrysiasis [9E1Z] Diseases of the visual system, unspecified Also known as: Diseases of the visual system, unspecified \| eye diseases NOS \| disorder of vision \| visual disorder [MC1Y] Other specified symptoms or signs involving the visual system Also known as: Other specified symptoms or signs involving the visual system \| Erythema of eyelid \| Visual disturbances \| disturbances of vision \| difficulty seeing [9D9Z] Vision impairment, unspecified Also known as: Vision impairment, unspecified \| sight impaired \| blindness and low vision \| impaired vision [9D90.2] Moderate vision impairment Also known as: Moderate vision impairment \| low vision, both eyes \| visual impairment category 2, in both eyes \| Low vision \| LW - [low vision] Includes: visual impairment category 2, in both eyes [QA00.6Z] Examination of eyes or vision, unspecified Also known as: Examination of eyes or vision, unspecified \| Examination of eyes or vision \| general eye examination \| routine eye examination \| vision examination === GRAPH WALKS === --- Walk 1 --- [PL11.2Z] Embolisation, as mode of injury or harm, unspecified --PARENT--> [PL11.2] Embolisation, as mode of injury or harm Def: An embolisation occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there.... --EXCLUDES--> [?] Obstruction of device, as mode of injury or harm Def: Obstruction associated with prosthetic devices, grafts or implants... --- Walk 2 --- [PL11.2Z] Embolisation, as mode of injury or harm, unspecified --PARENT--> [PL11.2] Embolisation, as mode of injury or harm Def: An embolisation occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there.... --EXCLUDES--> [?] Obstruction of device, as mode of injury or harm Def: Obstruction associated with prosthetic devices, grafts or implants... --- Walk 3 --- [QA50] Embolisation without injury or harm Def: An embolisation without documented injury or harm occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there.... --EXCLUDES--> [?] Embolisation, as mode of injury or harm Def: An embolisation occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there.... --CHILD--> [?] Air embolism, as mode of injury --- Walk 4 --- [QA50] Embolisation without injury or harm Def: An embolisation without documented injury or harm occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there.... --EXCLUDES--> [?] Embolisation, as mode of injury or harm Def: An embolisation occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there.... --EXCLUDES--> [?] Embolisation without injury or harm Def: An embolisation without documented injury or harm occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there.... --- Walk 5 --- [EL73.2] Adverse reaction to injection of neurotoxin Def: Adverse event resulting from use of neurotoxins, especially botulinum toxin, into the skin. This is most commonly administered for aesthetic reasons. Recognised problems include ptosis, diplopia and h... --PARENT--> [EL73] Unsatisfactory outcome from cutaneous cosmetic surgical procedure Def: The outcome from a surgical intervention designed to improve cosmetic appearance which is considered by the practitioner who performed the procedure to be less satisfactory than anticipated.... --PARENT--> [?] Complications of cutaneous cosmetic procedures --- Walk 6 --- [EL73.2] Adverse reaction to injection of neurotoxin Def: Adverse event resulting from use of neurotoxins, especially botulinum toxin, into the skin. This is most commonly administered for aesthetic reasons. Recognised problems include ptosis, diplopia and h... --PARENT--> [EL73] Unsatisfactory outcome from cutaneous cosmetic surgical procedure Def: The outcome from a surgical intervention designed to improve cosmetic appearance which is considered by the practitioner who performed the procedure to be less satisfactory than anticipated.... --CHILD--> [EL73.1] Adverse reaction to chemical peel Def: Any adverse reaction attributable to the use of chemical peels on the skin for cosmetic enhancement. Examples include infection, chemical burns, pustular acneform eruptions, dyspigmentation and scarri...	[ "[PL11.2Z] Embolisation, as mode of injury or harm, unspecified\n --PARENT--> [PL11.2] Embolisation, as mode of injury or harm\n Def: An embolisation occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there....\n --EXCLUDES--> [?] Obstruction of device, as mode of injury or harm\n Def: Obstruction associated with prosthetic devices, grafts or implants...", "[PL11.2Z] Embolisation, as mode of injury or harm, unspecified\n --PARENT--> [PL11.2] Embolisation, as mode of injury or harm\n Def: An embolisation occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there....\n --EXCLUDES--> [?] Obstruction of device, as mode of injury or harm\n Def: Obstruction associated with prosthetic devices, grafts or implants...", "[QA50] Embolisation without injury or harm\n Def: An embolisation without documented injury or harm occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there....\n --EXCLUDES--> [?] Embolisation, as mode of injury or harm\n Def: An embolisation occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there....\n --CHILD--> [?] Air embolism, as mode of injury", "[QA50] Embolisation without injury or harm\n Def: An embolisation without documented injury or harm occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there....\n --EXCLUDES--> [?] Embolisation, as mode of injury or harm\n Def: An embolisation occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there....\n --EXCLUDES--> [?] Embolisation without injury or harm\n Def: An embolisation without documented injury or harm occurs when a solid object within the venous or arterial circulation propagates to a distal location and becomes lodged there....", "[EL73.2] Adverse reaction to injection of neurotoxin\n Def: Adverse event resulting from use of neurotoxins, especially botulinum toxin, into the skin. This is most commonly administered for aesthetic reasons. Recognised problems include ptosis, diplopia and h...\n --PARENT--> [EL73] Unsatisfactory outcome from cutaneous cosmetic surgical procedure\n Def: The outcome from a surgical intervention designed to improve cosmetic appearance which is considered by the practitioner who performed the procedure to be less satisfactory than anticipated....\n --PARENT--> [?] Complications of cutaneous cosmetic procedures", "[EL73.2] Adverse reaction to injection of neurotoxin\n Def: Adverse event resulting from use of neurotoxins, especially botulinum toxin, into the skin. This is most commonly administered for aesthetic reasons. Recognised problems include ptosis, diplopia and h...\n --PARENT--> [EL73] Unsatisfactory outcome from cutaneous cosmetic surgical procedure\n Def: The outcome from a surgical intervention designed to improve cosmetic appearance which is considered by the practitioner who performed the procedure to be less satisfactory than anticipated....\n --CHILD--> [EL73.1] Adverse reaction to chemical peel\n Def: Any adverse reaction attributable to the use of chemical peels on the skin for cosmetic enhancement. Examples include infection, chemical burns, pustular acneform eruptions, dyspigmentation and scarri..." ]	PL11.2Z	Embolisation, as mode of injury or harm, unspecified	[ { "from_icd11": "QA50", "icd10_code": "XXI", "icd10_title": "" }, { "from_icd11": "ED6Y", "icd10_code": "L814", "icd10_title": "Other melanin hyperpigmentation" }, { "from_icd11": "9E1Z", "icd10_code": "H5500", "icd10_title": "Unspecified nystagmus" }, { "from_icd11": "9E1Z", "icd10_code": "H5509", "icd10_title": "Other forms of nystagmus" }, { "from_icd11": "9E1Z", "icd10_code": "H5581", "icd10_title": "Saccadic eye movements" }, { "from_icd11": "9E1Z", "icd10_code": "H5501", "icd10_title": "Congenital nystagmus" }, { "from_icd11": "9E1Z", "icd10_code": "H5502", "icd10_title": "Latent nystagmus" }, { "from_icd11": "9E1Z", "icd10_code": "H5589", "icd10_title": "Other irregular eye movements" }, { "from_icd11": "9E1Z", "icd10_code": "H5503", "icd10_title": "Visual deprivation nystagmus" }, { "from_icd11": "9E1Z", "icd10_code": "H5504", "icd10_title": "Dissociated nystagmus" }, { "from_icd11": "9E1Z", "icd10_code": "H44522", "icd10_title": "Atrophy of globe, left eye" }, { "from_icd11": "9E1Z", "icd10_code": "H3552", "icd10_title": "Pigmentary retinal dystrophy" }, { "from_icd11": "9E1Z", "icd10_code": "E70331", "icd10_title": "Hermansky-Pudlak syndrome" }, { "from_icd11": "9E1Z", "icd10_code": "H57812", "icd10_title": "Brow ptosis, left" }, { "from_icd11": "9E1Z", "icd10_code": "H5789", "icd10_title": "Other specified disorders of eye and adnexa" } ]	XXI
Medications can cause various side effects, such as joint pain, and can facilitate the production of autoantibodies, making it difficult to distinguish these side effects from collagen diseases. In this case, isoniazid was suspected as a possible cause because joint pain manifestation was similar to drug-induced lupus. In the tocilizumab treatment course, latent tuberculosis infection (LTBI) is a feared infectious disease. Treatment intervention is recommended for LTBI patients taking prednisolone or immunosuppressants because of the increased risk of active tuberculosis . Although isoniazid is included in the treatment regimen for LTBI, it has a moderate risk of drug-induced lupus erythematosus (DILE). The mechanism of DILE is unknown, but symptoms such as joint pain, muscle aches, fever, serositis, and rash generally appear within a few months to a few years of drug administration . Typically, the results for anti-nuclear and anti-histone antibodies are positive, and those for specific antibodies (anti-Ds-DNA and anti-Sm antibodies) are negative. In our case, isoniazid was not used to activate the LTBI. Since the results for all the specific antibodies were negative, the anti-histone antibody was speculated to be an anti-nuclear antibody. This suggested the possibility of drug-induced lupus caused by isoniazid. Thus, after confirming that the T-SPOT® test was negative, isoniazid was discontinued.	4.128906	0.523438	sec[2]/p[4]	en	0.999996	PMC9507323	https://doi.org/10.7759/cureus.28357	[ "anti", "isoniazid", "drug", "ltbi", "antibodies", "joint", "pain", "induced", "lupus", "cause" ]	[ { "code": "JA86.Y", "title": "Maternal care for other specified fetal problems" }, { "code": "MB23.1", "title": "Antisocial behaviour" }, { "code": "3B4Z", "title": "Coagulation defects, unspecified" }, { "code": "4A45.Z", "title": "Antiphospholipid syndrome, unspecified" }, { "code": "4A43.Y", "title": "Other specified overlap non-organ specific systemic autoimmune disease" }, { "code": "QE11.Z", "title": "Hazardous drug use, unspecified" }, { "code": "6C4G.2Z", "title": "Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecified" }, { "code": "NE60", "title": "Harmful effects of drugs, medicaments or biological substances, not elsewhere classified" }, { "code": "4A85.0Z", "title": "Drug hypersensitivity of unspecified type" }, { "code": "6C4G.3", "title": "Intoxication due to unknown or unspecified psychoactive substance" } ]	=== ICD-11 CODES FOUND === [JA86.Y] Maternal care for other specified fetal problems Also known as: Maternal care for other specified fetal problems \| Maternal care for other isoimmunization \| Isoimmunization NOS \| maternal antibodies NOS \| pregnancy management affected by incompatibility of blood groups NOS [MB23.1] Antisocial behaviour Definition: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated. Also known as: Antisocial behaviour \| Child or adolescent antisocial behaviour [3B4Z] Coagulation defects, unspecified Also known as: Coagulation defects, unspecified \| blood clotting disturbance \| blood clotting defect \| blood clotting factor deficiency \| clotting abnormality [4A45.Z] Antiphospholipid syndrome, unspecified Also known as: Antiphospholipid syndrome, unspecified \| Antiphospholipid syndrome \| Hughes syndrome \| Anticardiolipin syndrome [4A43.Y] Other specified overlap non-organ specific systemic autoimmune disease Also known as: Other specified overlap non-organ specific systemic autoimmune disease \| Antisynthetase syndrome \| Reynolds syndrome \| Syndromic multisystem autoimmune disease due to ITCH deficiency \| Eosinophilia myalgia syndrome [QE11.Z] Hazardous drug use, unspecified Also known as: Hazardous drug use, unspecified \| Hazardous drug use \| chronic drug use NOS \| chronic IV substance use \| drug use nos [6C4G.2Z] Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecified Also known as: Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecified \| Unknown or unspecified psychoactive substance dependence \| Drug dependence NOS [NE60] Harmful effects of drugs, medicaments or biological substances, not elsewhere classified Also known as: Harmful effects of drugs, medicaments or biological substances, not elsewhere classified \| drugs, medicaments or biological substances, toxicity not elsewhere classified \| adverse drug effects \| drug reaction NOS \| drug allergy NOS Excludes: Alcohol intoxication \| pathological drug intoxication \| hypersensitivity reaction to correctly administered drug [4A85.0Z] Drug hypersensitivity of unspecified type Also known as: Drug hypersensitivity of unspecified type \| Drug or pharmacological agents hypersensitivity \| medicinal hypersensitivity \| drug sensitivity NOS [6C4G.3] Intoxication due to unknown or unspecified psychoactive substance Definition: Intoxication due to unknown or unspecified psychoactive substance is a transient condition that develops during or shortly after the administration of an unknown or unspecified psychoactive substance that is characterised by disturbances in level of consciousness, cognition, perception, affect or behaviour, or other psychophysiological functions and responses. This diagnosis should be made only when there is strong evidence that an unidentified substance has been taken and the features cannot be Also known as: Intoxication due to unknown or unspecified psychoactive substance \| psychoactive substance abuse \| trance and possession disorders in psychoactive substance intoxication \| drug intoxication NOS === GRAPH WALKS === --- Walk 1 --- [JA86.Y] Maternal care for other specified fetal problems --PARENT--> [JA86] Maternal care for other fetal problems Def: A condition characterised by the provision of health interventions to the mother due to any other issue that is either suspected or known to be present in the fetus.... --CHILD--> [JA86.1] Maternal care for hydrops fetalis --- Walk 2 --- [JA86.Y] Maternal care for other specified fetal problems --PARENT--> [JA86] Maternal care for other fetal problems Def: A condition characterised by the provision of health interventions to the mother due to any other issue that is either suspected or known to be present in the fetus.... --CHILD--> [JA86.1] Maternal care for hydrops fetalis --- Walk 3 --- [MB23.1] Antisocial behaviour Def: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated.... --PARENT--> [MB23] Symptoms or signs involving appearance or behaviour --CHILD--> [MB23.2] Avoidance behaviour Def: The act of keeping away from circumstances, situations, or stimuli that cause anxiety or other negative emotions in the individual.... --- Walk 4 --- [MB23.1] Antisocial behaviour Def: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated.... --PARENT--> [MB23] Symptoms or signs involving appearance or behaviour --RELATED_TO--> [?] Speech dysfluency Def: Speech dysfluency is characterised by the frequent or pervasive disruption of the rhythmic flow of speech that arises subsequent to the developmental period (i.e., adult onset) and is outside the limi... --- Walk 5 --- [3B4Z] Coagulation defects, unspecified --PARENT--> [?] Coagulation defects --CHILD--> [?] Congenital or constitutional haemorrhagic condition Def: A condition caused by determinants arising during the antenatal period or genetically inherited factors, leading to defects in clotting mechanisms or abnormalities causing structural flaws in the bloo... --- Walk 6 --- [3B4Z] Coagulation defects, unspecified --PARENT--> [?] Coagulation defects --CHILD--> [?] Haemorrhagic diseases due to acquired coagulation factor defects Def: Any disease caused by determinants arising after birth. These diseases are characterised by abnormal coagulation of the blood....	[ "[JA86.Y] Maternal care for other specified fetal problems\n --PARENT--> [JA86] Maternal care for other fetal problems\n Def: A condition characterised by the provision of health interventions to the mother due to any other issue that is either suspected or known to be present in the fetus....\n --CHILD--> [JA86.1] Maternal care for hydrops fetalis", "[JA86.Y] Maternal care for other specified fetal problems\n --PARENT--> [JA86] Maternal care for other fetal problems\n Def: A condition characterised by the provision of health interventions to the mother due to any other issue that is either suspected or known to be present in the fetus....\n --CHILD--> [JA86.1] Maternal care for hydrops fetalis", "[MB23.1] Antisocial behaviour\n Def: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated....\n --PARENT--> [MB23] Symptoms or signs involving appearance or behaviour\n --CHILD--> [MB23.2] Avoidance behaviour\n Def: The act of keeping away from circumstances, situations, or stimuli that cause anxiety or other negative emotions in the individual....", "[MB23.1] Antisocial behaviour\n Def: Behaviour in which the basic rights of others or major age-appropriate societal norms, rules, or laws, are violated....\n --PARENT--> [MB23] Symptoms or signs involving appearance or behaviour\n --RELATED_TO--> [?] Speech dysfluency\n Def: Speech dysfluency is characterised by the frequent or pervasive disruption of the rhythmic flow of speech that arises subsequent to the developmental period (i.e., adult onset) and is outside the limi...", "[3B4Z] Coagulation defects, unspecified\n --PARENT--> [?] Coagulation defects\n --CHILD--> [?] Congenital or constitutional haemorrhagic condition\n Def: A condition caused by determinants arising during the antenatal period or genetically inherited factors, leading to defects in clotting mechanisms or abnormalities causing structural flaws in the bloo...", "[3B4Z] Coagulation defects, unspecified\n --PARENT--> [?] Coagulation defects\n --CHILD--> [?] Haemorrhagic diseases due to acquired coagulation factor defects\n Def: Any disease caused by determinants arising after birth. These diseases are characterised by abnormal coagulation of the blood...." ]	JA86.Y	Maternal care for other specified fetal problems	[ { "from_icd11": "JA86.Y", "icd10_code": "O26841 ", "icd10_title": "" }, { "from_icd11": "JA86.Y", "icd10_code": "O26843 ", "icd10_title": "" }, { "from_icd11": "JA86.Y", "icd10_code": "O26849 ", "icd10_title": "" }, { "from_icd11": "JA86.Y", "icd10_code": "O3680X0 ", "icd10_title": "" }, { "from_icd11": "3B4Z", "icd10_code": "D688", "icd10_title": "Other specified coagulation defects" }, { "from_icd11": "3B4Z", "icd10_code": "D689", "icd10_title": "Coagulation defect, unspecified" }, { "from_icd11": "3B4Z", "icd10_code": "D699", "icd10_title": "Hemorrhagic condition, unspecified" }, { "from_icd11": "3B4Z", "icd10_code": "D698", "icd10_title": "Other specified hemorrhagic conditions" }, { "from_icd11": "3B4Z", "icd10_code": "D65-D69", "icd10_title": "" }, { "from_icd11": "3B4Z", "icd10_code": "D69", "icd10_title": "Purpura and other hemorrhagic conditions" }, { "from_icd11": "4A45.Z", "icd10_code": "D6861", "icd10_title": "Antiphospholipid syndrome" }, { "from_icd11": "4A45.Z", "icd10_code": "D6869", "icd10_title": "Other thrombophilia" }, { "from_icd11": "4A45.Z", "icd10_code": "D6862", "icd10_title": "Lupus anticoagulant syndrome" }, { "from_icd11": "4A45.Z", "icd10_code": "D686", "icd10_title": "Other thrombophilia" }, { "from_icd11": "QE11.Z", "icd10_code": "Z722", "icd10_title": "" } ]	O26841
Four weeks later, the patient presented with upper abdominal fullness not associated with any other complaint. He was afebrile and hemodynamically stable. There was no icterus. On examination, there was distension of abdomen limited to the upper half of abdomen. There was no demonstrable free fluid and bowel sounds were normal. Laboratory values were: Hb-9.2 gms/dl, TLC-6900/mm3, serum bilirubin-0.8 mg%, ALT-17 U/ L, ALP 365 U/ L, AST-28 U/ L. Sonography revealed a large multiloculated cystic mass (15cmx13cmx18 cm) antero-superior to the liver. The intra-hepatic biliary radicals and the common bile duct were not dilated. There was no free fluid. CT scan was done to know further details. It showed 13cmx13cmx16 cm cystic lesion in the right lobe of liver with well defined septa of liver parenchyma within it . Another cystic lesion was found in the left sub-hepatic space and lesser sac. Based on the findings it was diagnosed to be a “walled off” bile collection. A pig tail catheter was inserted percutaneously into the bilioma under sonographic guidance which was both diagnostic and therapeutic. It drained about 500 ml of greenish brown fluid overnight and culminated with disappearance of abdominal distension. The catheter was removed after 4 days when the effluent was negligible. Patient was discharged and on follow up 3 weeks later, found to be doing well. Currently patient is on albendazole therapy.	3.580078	0.987793	sec[1]/p[4]	en	0.999996	22953304	N/A	[ "fluid", "cystic", "liver", "abdominal", "distension", "abdomen", "free", "hepatic", "bile", "lesion" ]	[ { "code": "FA36.Z", "title": "Effusion of joint, unspecified" }, { "code": "5C70.0", "title": "Dehydration" }, { "code": "5C78", "title": "Fluid overload" }, { "code": "MG29.Z", "title": "Oedema, unspecified" }, { "code": "ME04.Z", "title": "Ascites, unspecified" }, { "code": "CA25.Z", "title": "Cystic fibrosis, unspecified" }, { "code": "CB40.Y", "title": "Other specified diseases of the respiratory system" }, { "code": "GB71.0", "title": "Calculus in bladder" }, { "code": "DB99.1Z", "title": "Hepatic cyst, unspecified" }, { "code": "5A01.2", "title": "Nontoxic multinodular goitre" } ]	=== ICD-11 CODES FOUND === [FA36.Z] Effusion of joint, unspecified Also known as: Effusion of joint, unspecified \| Effusion of joint \| effusion into joint \| effusion of joint, site unspecified \| hydrarthrosis [5C70.0] Dehydration Definition: Dehydration occurs when there is an insufficient amount or excessive loss of water in the body. This can be caused by vomiting, diarrhoea, fever, use of diuretics, profuse sweating, or decreased water intake. Also known as: Dehydration \| fluid depletion \| anhydration \| anhydremia \| fluid volume deficit [5C78] Fluid overload Definition: This is the condition where there is too much fluid in the blood. The opposite condition is hypovolemia, which is too little fluid volume in the blood. Fluid volume excess in the intravascular compartment occurs due to an increase in total body sodium content and a consequent increase in extracellular body water. The mechanism usually stems from compromised regulatory mechanisms for sodium handling as seen in congestive heart failure (CHF), kidney failure, and liver failure. It may also be cause Also known as: Fluid overload \| fluid excess \| fluid volume excess \| hypervolemia \| volume excess [MG29.Z] Oedema, unspecified Also known as: Oedema, unspecified \| Oedema \| dropsy \| hydrops \| Fluid retention NOS [ME04.Z] Ascites, unspecified Also known as: Ascites, unspecified \| Ascites \| abdominal dropsy \| hydrops abdominis \| ascites NOS [CA25.Z] Cystic fibrosis, unspecified Also known as: Cystic fibrosis, unspecified \| Cystic fibrosis \| mucoviscidosis \| CF - [cystic fibrosis] \| cystic fibrosis nos [CB40.Y] Other specified diseases of the respiratory system Also known as: Other specified diseases of the respiratory system \| Secondary respiratory disorders \| Respiratory disorders in diseases classified elsewhere \| Diseases of bronchus, not elsewhere classified \| Acquired bronchial diverticulum [GB71.0] Calculus in bladder Definition: A condition caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. This condition is characterised by urinary calculi located in the bladder. This condition may also present with haematuria, dysuria, or pain in the flank, lower abdomen, or groin. Confirmation is by abdominal radiography, to determine the presence and location of calculi. Also known as: Calculus in bladder \| Urinary bladder stone \| bladder calculi \| bladder stone \| urinary bladder calculus Includes: Urinary bladder stone Excludes: Calculus in a bowel segment for urinary diversion (e.g. neobladder, pouch) (NFBC) [DB99.1Z] Hepatic cyst, unspecified Also known as: Hepatic cyst, unspecified \| Hepatic cyst \| cyst of liver \| cystic liver \| liver cyst [5A01.2] Nontoxic multinodular goitre Definition: Multiple nodules of the thyroid gland due to follicular multiplication, unaccompanied by hyperthyroidism or thyrotoxicosis Also known as: Nontoxic multinodular goitre \| non-toxic multinodular goitre \| multinodular nontoxic struma \| cystic goitre \| Cystic goitre NOS === GRAPH WALKS === --- Walk 1 --- [FA36.Z] Effusion of joint, unspecified --PARENT--> [FA36] Effusion of joint Def: Increased intra-articular fluid secondary to trauma and/or other acquired conditions not detailed in other codes.... --CHILD--> [FA36.Z] Effusion of joint, unspecified --- Walk 2 --- [FA36.Z] Effusion of joint, unspecified --PARENT--> [FA36] Effusion of joint Def: Increased intra-articular fluid secondary to trauma and/or other acquired conditions not detailed in other codes.... --EXCLUDES--> [?] Tertiary yaws Def: Tertiary yaws develops in <10% of untreated infected individuals after and interval of 5 years or more. The late stage skin lesions are characterised by gummatous nodules with necrotic tissue destruct... --- Walk 3 --- [5C70.0] Dehydration Def: Dehydration occurs when there is an insufficient amount or excessive loss of water in the body. This can be caused by vomiting, diarrhoea, fever, use of diuretics, profuse sweating, or decreased water... --RELATED_TO--> [?] Dehydration of newborn Def: A paediatric condition characterised by excessive loss of body water in a newborn.... --PARENT--> [?] Dehydration Def: Dehydration occurs when there is an insufficient amount or excessive loss of water in the body. This can be caused by vomiting, diarrhoea, fever, use of diuretics, profuse sweating, or decreased water... --- Walk 4 --- [5C70.0] Dehydration Def: Dehydration occurs when there is an insufficient amount or excessive loss of water in the body. This can be caused by vomiting, diarrhoea, fever, use of diuretics, profuse sweating, or decreased water... --RELATED_TO--> [?] Dehydration of newborn Def: A paediatric condition characterised by excessive loss of body water in a newborn.... --PARENT--> [?] Dehydration Def: Dehydration occurs when there is an insufficient amount or excessive loss of water in the body. This can be caused by vomiting, diarrhoea, fever, use of diuretics, profuse sweating, or decreased water... --- Walk 5 --- [5C78] Fluid overload Def: This is the condition where there is too much fluid in the blood. The opposite condition is hypovolemia, which is too little fluid volume in the blood. Fluid volume excess in the intravascular compart... --PARENT--> [?] Disorders of fluid, electrolyte or acid-base balance --PARENT--> [?] Metabolic disorders --- Walk 6 --- [5C78] Fluid overload Def: This is the condition where there is too much fluid in the blood. The opposite condition is hypovolemia, which is too little fluid volume in the blood. Fluid volume excess in the intravascular compart... --PARENT--> [?] Disorders of fluid, electrolyte or acid-base balance --CHILD--> [5C72] Hypo-osmolality or hyponatraemia Def: Serum sodium concentrations of less than 135 mEq/L; decreased serum concentration of osmotically active particles...	[ "[FA36.Z] Effusion of joint, unspecified\n --PARENT--> [FA36] Effusion of joint\n Def: Increased intra-articular fluid secondary to trauma and/or other acquired conditions not detailed in other codes....\n --CHILD--> [FA36.Z] Effusion of joint, unspecified", "[FA36.Z] Effusion of joint, unspecified\n --PARENT--> [FA36] Effusion of joint\n Def: Increased intra-articular fluid secondary to trauma and/or other acquired conditions not detailed in other codes....\n --EXCLUDES--> [?] Tertiary yaws\n Def: Tertiary yaws develops in <10% of untreated infected individuals after and interval of 5 years or more. The late stage skin lesions are characterised by gummatous nodules with necrotic tissue destruct...", "[5C70.0] Dehydration\n Def: Dehydration occurs when there is an insufficient amount or excessive loss of water in the body. This can be caused by vomiting, diarrhoea, fever, use of diuretics, profuse sweating, or decreased water...\n --RELATED_TO--> [?] Dehydration of newborn\n Def: A paediatric condition characterised by excessive loss of body water in a newborn....\n --PARENT--> [?] Dehydration\n Def: Dehydration occurs when there is an insufficient amount or excessive loss of water in the body. This can be caused by vomiting, diarrhoea, fever, use of diuretics, profuse sweating, or decreased water...", "[5C70.0] Dehydration\n Def: Dehydration occurs when there is an insufficient amount or excessive loss of water in the body. This can be caused by vomiting, diarrhoea, fever, use of diuretics, profuse sweating, or decreased water...\n --RELATED_TO--> [?] Dehydration of newborn\n Def: A paediatric condition characterised by excessive loss of body water in a newborn....\n --PARENT--> [?] Dehydration\n Def: Dehydration occurs when there is an insufficient amount or excessive loss of water in the body. This can be caused by vomiting, diarrhoea, fever, use of diuretics, profuse sweating, or decreased water...", "[5C78] Fluid overload\n Def: This is the condition where there is too much fluid in the blood. The opposite condition is hypovolemia, which is too little fluid volume in the blood. Fluid volume excess in the intravascular compart...\n --PARENT--> [?] Disorders of fluid, electrolyte or acid-base balance\n --PARENT--> [?] Metabolic disorders", "[5C78] Fluid overload\n Def: This is the condition where there is too much fluid in the blood. The opposite condition is hypovolemia, which is too little fluid volume in the blood. Fluid volume excess in the intravascular compart...\n --PARENT--> [?] Disorders of fluid, electrolyte or acid-base balance\n --CHILD--> [5C72] Hypo-osmolality or hyponatraemia\n Def: Serum sodium concentrations of less than 135 mEq/L; decreased serum concentration of osmotically active particles..." ]	FA36.Z	Effusion of joint, unspecified	[ { "from_icd11": "FA36.Z", "icd10_code": "M25471", "icd10_title": "Effusion, right ankle" }, { "from_icd11": "FA36.Z", "icd10_code": "M25461", "icd10_title": "Effusion, right knee" }, { "from_icd11": "FA36.Z", "icd10_code": "M25462", "icd10_title": "Effusion, left knee" }, { "from_icd11": "FA36.Z", "icd10_code": "M25431", "icd10_title": "Effusion, right wrist" }, { "from_icd11": "FA36.Z", "icd10_code": "M25472", "icd10_title": "Effusion, left ankle" }, { "from_icd11": "FA36.Z", "icd10_code": "M25451", "icd10_title": "Effusion, right hip" }, { "from_icd11": "FA36.Z", "icd10_code": "M2548", "icd10_title": "Effusion, other site" }, { "from_icd11": "FA36.Z", "icd10_code": "M25411", "icd10_title": "Effusion, right shoulder" }, { "from_icd11": "FA36.Z", "icd10_code": "M25441", "icd10_title": "Effusion, right hand" }, { "from_icd11": "FA36.Z", "icd10_code": "M25452", "icd10_title": "Effusion, left hip" }, { "from_icd11": "FA36.Z", "icd10_code": "M25421", "icd10_title": "Effusion, right elbow" }, { "from_icd11": "FA36.Z", "icd10_code": "M25432", "icd10_title": "Effusion, left wrist" }, { "from_icd11": "FA36.Z", "icd10_code": "M25473", "icd10_title": "Effusion, unspecified ankle" }, { "from_icd11": "FA36.Z", "icd10_code": "M25412", "icd10_title": "Effusion, left shoulder" }, { "from_icd11": "FA36.Z", "icd10_code": "M25422", "icd10_title": "Effusion, left elbow" } ]	M25471	Effusion, right ankle
It is well known that foreign bodies in the urinary collecting system can induce stone formation . In the present case the foreign body inducing stone formation was a metal coil, which partly migrated into the collecting system. The history of the patient with a myelomeningocele, neurogenic bladder dysfunction, intermittent self-catheterization, recurrent urinary tract infections and right-sided pyelonephritis is suggestive for the development of infection stones. Although the stone analysis after bilateral pyelolithotomy is not available, it is likely that the initial staghorn calculi consisted, at least to some extent, of the typical infection stone material struvite. Patients with musculoskeletal anomalies are more likely to have a stone composition of struvite due to recurrent urinary tract infections . However, the patient in the present case never had a pyelonephritis on the left side and the analysis of the left-sided composite stone revealed a pure calcium-oxalate/apatite composition. It has recently been shown that improved patient care in the last two decades resulted in a significant change of the predominant stone composition in these patients . Nowadays, struvite stones account only for approximately 20% of all stones while stones not related to urinary tract infections such as apatite and calcium oxalate stones are found in approximately 80% of all renal stones in this patient group .	4.21875	0.587891	sec[2]/p[4]	en	0.999994	23758632	https://doi.org/10.1186/1471-2490-13-29	[ "stone", "stones", "urinary", "that", "tract", "infections", "struvite", "composition", "foreign", "collecting" ]	[ { "code": "GB70.Z", "title": "Calculus of upper urinary tract, unspecified" }, { "code": "GB70.0Z", "title": "Calculus of kidney, unspecified" }, { "code": "DC11.3", "title": "Calculus of gallbladder or cystic duct without cholecystitis or cholangitis" }, { "code": "DA04.4", "title": "Sialolithiasis" }, { "code": "GB71.0", "title": "Calculus in bladder" }, { "code": "GB6Z", "title": "Kidney failure, unspecified" }, { "code": "GC04.Z", "title": "Fistula of the genitourinary tract, unspecified" }, { "code": "MF51", "title": "Anuria or oliguria" }, { "code": "GC2Z", "title": "Diseases of the urinary system, unspecified" }, { "code": "8A80.Z", "title": "Migraine, unspecified" } ]	=== ICD-11 CODES FOUND === [GB70.Z] Calculus of upper urinary tract, unspecified Also known as: Calculus of upper urinary tract, unspecified \| Calculus of upper urinary tract \| calculus of urinary tract NOS \| urinary calculi \| urinary calculus, unspecified [GB70.0Z] Calculus of kidney, unspecified Also known as: Calculus of kidney, unspecified \| Calculus of kidney \| Renal calculus or stone \| Stone in kidney \| kidney calculi [DC11.3] Calculus of gallbladder or cystic duct without cholecystitis or cholangitis Definition: Stones in gallbladder present without inflammation of the gall bladder wall and bile duct. Also known as: Calculus of gallbladder or cystic duct without cholecystitis or cholangitis \| cholesterol calculi \| cholesterol calculus \| Cholelithiasis unspecified and without cholecystitis or cholangitis \| calculous disease of gallbladder [DA04.4] Sialolithiasis Definition: Sialolithiasis is a condition where a calcified mass forms within a salivary gland, usually in the duct of the submandibular gland. The usual symptoms are pain and swelling of the affected salivary gland, both of which get worse when salivary flow is stimulated. Also known as: Sialolithiasis \| Calculus of salivary gland or duct \| Stone of salivary gland or duct \| calculus of salivary gland \| salivary calculus Includes: Calculus of salivary gland or duct \| Stone of salivary gland or duct [GB71.0] Calculus in bladder Definition: A condition caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. This condition is characterised by urinary calculi located in the bladder. This condition may also present with haematuria, dysuria, or pain in the flank, lower abdomen, or groin. Confirmation is by abdominal radiography, to determine the presence and location of calculi. Also known as: Calculus in bladder \| Urinary bladder stone \| bladder calculi \| bladder stone \| urinary bladder calculus Includes: Urinary bladder stone Excludes: Calculus in a bowel segment for urinary diversion (e.g. neobladder, pouch) (NFBC) [GB6Z] Kidney failure, unspecified Also known as: Kidney failure, unspecified \| nontraumatic kidney injury \| renal failure NOS \| kidney block \| renal impairment NOS [GC04.Z] Fistula of the genitourinary tract, unspecified Also known as: Fistula of the genitourinary tract, unspecified \| Fistula of the genitourinary tract \| persistent urinary fistula \| persistent urinary tract fistula \| recurrent urinary fistula [MF51] Anuria or oliguria Definition: Anuria means nonpassage of urine, in practice is defined as passage of less than 50 millilitres of urine in a day. Oliguria is the low output of urine. It is clinically classified as an output below 300-500ml/day. Also known as: Anuria or oliguria \| Anuria \| suppression of urinary secretion \| ischuria \| Oliguria Excludes: Maternal care for other conditions predominantly related to pregnancy [GC2Z] Diseases of the urinary system, unspecified Also known as: Diseases of the urinary system, unspecified \| urinary tract disease NOS \| Abnormal renal function \| kidney dysfunction NOS \| kidney hypofunction [8A80.Z] Migraine, unspecified Also known as: Migraine, unspecified \| Migraine === GRAPH WALKS === --- Walk 1 --- [GB70.Z] Calculus of upper urinary tract, unspecified --PARENT--> [GB70] Calculus of upper urinary tract Def: A condition of the urinary system, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. Th... --CHILD--> [GB70.1] Calculus of ureter Def: A condition of the ureter, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. This condi... --- Walk 2 --- [GB70.Z] Calculus of upper urinary tract, unspecified --PARENT--> [GB70] Calculus of upper urinary tract Def: A condition of the urinary system, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. Th... --CHILD--> [GB70.0] Calculus of kidney Def: A condition of the kidney, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. This condi... --- Walk 3 --- [GB70.0Z] Calculus of kidney, unspecified --PARENT--> [GB70.0] Calculus of kidney Def: A condition of the kidney, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. This condi... --CHILD--> [GB70.00] Staghorn calculus Def: A condition of the kidney, characterised by large, branched, struvite or calcium carbonate apatite calculi within the renal pelvis and extending into one or more caliceal extensions, and fever, haemat... --- Walk 4 --- [GB70.0Z] Calculus of kidney, unspecified --PARENT--> [GB70.0] Calculus of kidney Def: A condition of the kidney, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. This condi... --CHILD--> [GB70.0Y] Other specified calculus of kidney --- Walk 5 --- [DC11.3] Calculus of gallbladder or cystic duct without cholecystitis or cholangitis Def: Stones in gallbladder present without inflammation of the gall bladder wall and bile duct.... --PARENT--> [DC11] Cholelithiasis Def: Cholelithiasis is calculus of gallbladder, cystic duct or bile duct. Most stones in the gallbladder are asymptomatic, but the most common initial symptom is biliary colic before the development of com... --CHILD--> [DC11.0] Calculus of gallbladder or cystic duct with acute cholecystitis Def: Stones in gallbladder or cystic duct present with acute inflammation of the gall bladder wall typically follows the cystic duct obstruction by the stone.... --- Walk 6 --- [DC11.3] Calculus of gallbladder or cystic duct without cholecystitis or cholangitis Def: Stones in gallbladder present without inflammation of the gall bladder wall and bile duct.... --PARENT--> [DC11] Cholelithiasis Def: Cholelithiasis is calculus of gallbladder, cystic duct or bile duct. Most stones in the gallbladder are asymptomatic, but the most common initial symptom is biliary colic before the development of com... --CHILD--> [DC11.0] Calculus of gallbladder or cystic duct with acute cholecystitis Def: Stones in gallbladder or cystic duct present with acute inflammation of the gall bladder wall typically follows the cystic duct obstruction by the stone....	[ "[GB70.Z] Calculus of upper urinary tract, unspecified\n --PARENT--> [GB70] Calculus of upper urinary tract\n Def: A condition of the urinary system, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. Th...\n --CHILD--> [GB70.1] Calculus of ureter\n Def: A condition of the ureter, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. This condi...", "[GB70.Z] Calculus of upper urinary tract, unspecified\n --PARENT--> [GB70] Calculus of upper urinary tract\n Def: A condition of the urinary system, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. Th...\n --CHILD--> [GB70.0] Calculus of kidney\n Def: A condition of the kidney, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. This condi...", "[GB70.0Z] Calculus of kidney, unspecified\n --PARENT--> [GB70.0] Calculus of kidney\n Def: A condition of the kidney, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. This condi...\n --CHILD--> [GB70.00] Staghorn calculus\n Def: A condition of the kidney, characterised by large, branched, struvite or calcium carbonate apatite calculi within the renal pelvis and extending into one or more caliceal extensions, and fever, haemat...", "[GB70.0Z] Calculus of kidney, unspecified\n --PARENT--> [GB70.0] Calculus of kidney\n Def: A condition of the kidney, caused by dehydration, decreased urine volume or fluid flow rates, or increased excretion of minerals such as calcium, oxalate, magnesium, cystine, and phosphate. This condi...\n --CHILD--> [GB70.0Y] Other specified calculus of kidney", "[DC11.3] Calculus of gallbladder or cystic duct without cholecystitis or cholangitis\n Def: Stones in gallbladder present without inflammation of the gall bladder wall and bile duct....\n --PARENT--> [DC11] Cholelithiasis\n Def: Cholelithiasis is calculus of gallbladder, cystic duct or bile duct. Most stones in the gallbladder are asymptomatic, but the most common initial symptom is biliary colic before the development of com...\n --CHILD--> [DC11.0] Calculus of gallbladder or cystic duct with acute cholecystitis\n Def: Stones in gallbladder or cystic duct present with acute inflammation of the gall bladder wall typically follows the cystic duct obstruction by the stone....", "[DC11.3] Calculus of gallbladder or cystic duct without cholecystitis or cholangitis\n Def: Stones in gallbladder present without inflammation of the gall bladder wall and bile duct....\n --PARENT--> [DC11] Cholelithiasis\n Def: Cholelithiasis is calculus of gallbladder, cystic duct or bile duct. Most stones in the gallbladder are asymptomatic, but the most common initial symptom is biliary colic before the development of com...\n --CHILD--> [DC11.0] Calculus of gallbladder or cystic duct with acute cholecystitis\n Def: Stones in gallbladder or cystic duct present with acute inflammation of the gall bladder wall typically follows the cystic duct obstruction by the stone...." ]	GB70.Z	Calculus of upper urinary tract, unspecified	[ { "from_icd11": "GB70.Z", "icd10_code": "N202", "icd10_title": "Calculus of kidney with calculus of ureter" }, { "from_icd11": "GB70.Z", "icd10_code": "N209", "icd10_title": "Urinary calculus, unspecified" }, { "from_icd11": "GB70.Z", "icd10_code": "N20", "icd10_title": "Calculus of kidney and ureter" }, { "from_icd11": "GB70.0Z", "icd10_code": "N200", "icd10_title": "Calculus of kidney" }, { "from_icd11": "DC11.3", "icd10_code": "K8021", "icd10_title": "Calculus of gallbladder without cholecystitis with obstruction" }, { "from_icd11": "DC11.3", "icd10_code": "K8020", "icd10_title": "Calculus of gallbladder without cholecystitis without obstruction" }, { "from_icd11": "DC11.3", "icd10_code": "K802", "icd10_title": "Calculus of gallbladder without cholecystitis" }, { "from_icd11": "DA04.4", "icd10_code": "K115", "icd10_title": "Sialolithiasis" }, { "from_icd11": "GB71.0", "icd10_code": "N210", "icd10_title": "Calculus in bladder" }, { "from_icd11": "GB6Z", "icd10_code": "N19", "icd10_title": "Unspecified kidney failure" }, { "from_icd11": "GB6Z", "icd10_code": "N17-N19", "icd10_title": "" }, { "from_icd11": "GB6Z", "icd10_code": "N17", "icd10_title": "Acute kidney failure" }, { "from_icd11": "GC04.Z", "icd10_code": "N321", "icd10_title": "Vesicointestinal fistula" }, { "from_icd11": "MF51", "icd10_code": "R34", "icd10_title": "Anuria and oliguria" }, { "from_icd11": "8A80.Z", "icd10_code": "G43B0", "icd10_title": "Ophthalmoplegic migraine, not intractable" } ]	N202	Calculus of kidney with calculus of ureter
A 60-year-old male presented with a pelvic soft tissue mass, subcutaneous deposits, lung and bony metastases without any evidence of a primary tumor. A subcutaneous deposit was biopsied, disclosing an adenocarcinoma positive for cytokeratins and negative for vimentin. The patient was managed with oxaliplatin + irinotecan for 4 months in the context of a CUP clinical trial, failed to respond and subsequently received paclitaxel/carboplatin combination chemotherapy. This resulted in partial remission of the malignancy and an overall survival of 20 months. The final clinical diagnoses were either lung adenocarcinoma or pancreatic adenocarcinoma. In contrast, the 64 microRNA assay suggested small cell lung carcinoma as the first result, and large cell or adenocarcinoma of the lung as the second result. The biopsied tissue was then analyzed with another microRNA based assay, Rosetta Lung Cancer Test™ and the result supported the first assay answer (the higher confidence result) of small cell lung carcinoma. Additional IHC work up on the archived bioptic material resulted in a diagnosis that was in agreement with the 64 microRNA assay first answer of small cell lung carcinoma. This knowledge could have prevented the administration of ineffective oxaliplatin/irinotecan therapy to the patient, and could have resulted in the administration of platinum-based regimens earlier during the course of the disease.	4.050781	0.976563	sec[1]/sec[1]/p[0]	en	0.999995	23758919	https://doi.org/10.1186/1476-4598-12-57	[ "lung", "adenocarcinoma", "assay", "cell", "resulted", "microrna", "small", "carcinoma", "tissue", "subcutaneous" ]	[ { "code": "CB40.Y", "title": "Other specified diseases of the respiratory system" }, { "code": "LA75.1", "title": "Agenesis of lung" }, { "code": "CA40.Z", "title": "Pneumonia, organism unspecified" }, { "code": "CB41", "title": "Respiratory failure" }, { "code": "NB32.3Y", "title": "Other injury of lung" }, { "code": "2D40", "title": "Adenocarcinoma of unspecified site" }, { "code": "2C0Y", "title": "Other specified malignant neoplasms of intestine" }, { "code": "2C25.0", "title": "Adenocarcinoma of bronchus or lung" }, { "code": "2C94.0", "title": "Adenocarcinoma of urinary bladder" }, { "code": "2B70.0Z", "title": "Adenocarcinoma of oesophagus, unspecified" } ]	=== ICD-11 CODES FOUND === [CB40.Y] Other specified diseases of the respiratory system Also known as: Other specified diseases of the respiratory system \| Secondary respiratory disorders \| Respiratory disorders in diseases classified elsewhere \| Diseases of bronchus, not elsewhere classified \| Acquired bronchial diverticulum [LA75.1] Agenesis of lung Definition: This refers to the absence or rudimentary residua of an undeveloped lung. Also known as: Agenesis of lung \| Pulmonary agenesis \| absence of lung \| aplasia of lung \| apulmonism [CA40.Z] Pneumonia, organism unspecified Also known as: Pneumonia, organism unspecified \| Pneumonia \| infectious pneumonia \| PN - [pneumonia] \| lobar pneumonia NOS [CB41] Respiratory failure Definition: Respiratory failure is a life-threatening impairment of oxygenation or carbon dioxide (CO2) elimination. Respiratory failure may occur because of impaired gas exchange, decreased ventilation, or both. The level of oxygen in the blood becomes dangerously low or the level of carbon dioxide becomes dangerously high. Also known as: Respiratory failure \| lung failure NOS \| pulmonary failure Excludes: Acute respiratory distress syndrome \| Respiratory arrest \| Respiratory distress of newborn [NB32.3Y] Other injury of lung Also known as: Other injury of lung \| Haematoma of lung \| Traumatic hydropneumothorax \| Acute traumatic lung congestion \| Rupture of lung [2D40] Adenocarcinoma of unspecified site Definition: A common cancer characterised by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma. Also known as: Adenocarcinoma of unspecified site \| adenoacanthoma of unspecified site \| adenocarcinoid of unspecified site \| adenocarcinoid tumour of unspecified site \| adenocarcinoma and carcinoid combined of unspecified site [2C0Y] Other specified malignant neoplasms of intestine Also known as: Other specified malignant neoplasms of intestine \| Adenocarcinoma of intestine \| adenocarcinoma of intestine NOS [2C25.0] Adenocarcinoma of bronchus or lung Definition: A carcinoma that arises from the lung and is characterised by the presence of malignant glandular epithelial cells. There is a male predilection with a male to female ratio of 2:1. Usually lung adenocarcinoma is asymptomatic and is identified through screening studies or as an incidental radiologic finding. If clinical symptoms are present they include shortness of breath, cough, hemoptysis, chest pain, and fever. Tobacco smoke is a known risk factor. Also known as: Adenocarcinoma of bronchus or lung \| primary lung adenocarcinoma \| lung adenocarcinoma \| bronchiolar adenocarcinoma of unspecified site \| Mucinous adenocarcinoma of lung [2C94.0] Adenocarcinoma of urinary bladder Definition: A rare adenocarcinoma arising from metaplastic bladder epithelium. It is frequently associated with long-standing local irritation. The majority of cases originate from the trigone and the posterior wall of the bladder. Also known as: Adenocarcinoma of urinary bladder \| Adenocarcinoma of bladder [2B70.0Z] Adenocarcinoma of oesophagus, unspecified Also known as: Adenocarcinoma of oesophagus, unspecified \| Adenocarcinoma of oesophagus \| oesophageal adenocarcinoma === GRAPH WALKS === --- Walk 1 --- [CB40.Y] Other specified diseases of the respiratory system --PARENT--> [CB40] Certain diseases of the respiratory system --RELATED_TO--> [?] Pulmonary sporotrichosis Def: Pulmonary forms of infection, although uncommon, can occur when Sporothrix schenckii conidia are inhaled. Symptoms of pulmonary sporotrichosis mimic those of tuberculosis including constitutional com... --- Walk 2 --- [CB40.Y] Other specified diseases of the respiratory system --PARENT--> [CB40] Certain diseases of the respiratory system --RELATED_TO--> [?] Airway obstruction in the neonate due to airway abnormality --- Walk 3 --- [LA75.1] Agenesis of lung Def: This refers to the absence or rudimentary residua of an undeveloped lung.... --PARENT--> [LA75] Structural developmental anomalies of lungs Def: Any condition caused by failure of the lungs to correctly develop during the antenatal period.... --CHILD--> [LA75.1] Agenesis of lung Def: This refers to the absence or rudimentary residua of an undeveloped lung.... --- Walk 4 --- [LA75.1] Agenesis of lung Def: This refers to the absence or rudimentary residua of an undeveloped lung.... --PARENT--> [LA75] Structural developmental anomalies of lungs Def: Any condition caused by failure of the lungs to correctly develop during the antenatal period.... --PARENT--> [?] Structural developmental anomalies of the respiratory system --- Walk 5 --- [CA40.Z] Pneumonia, organism unspecified --PARENT--> [CA40] Pneumonia Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ... --RELATED_TO--> [?] Congenital pneumonia Def: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi.... --- Walk 6 --- [CA40.Z] Pneumonia, organism unspecified --PARENT--> [CA40] Pneumonia Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ... --CHILD--> [CA40.1] Viral pneumonia Def: A disease of the pulmonary system, caused by an infection with a viral source. This disease is characterised by fever, lethargy, headache, myalgia, vomiting, or coughing. Transmission is by inhalation...	[ "[CB40.Y] Other specified diseases of the respiratory system\n --PARENT--> [CB40] Certain diseases of the respiratory system\n --RELATED_TO--> [?] Pulmonary sporotrichosis\n Def: Pulmonary forms of infection, although uncommon, can occur when Sporothrix schenckii conidia are inhaled. \nSymptoms of pulmonary sporotrichosis mimic those of tuberculosis including constitutional com...", "[CB40.Y] Other specified diseases of the respiratory system\n --PARENT--> [CB40] Certain diseases of the respiratory system\n --RELATED_TO--> [?] Airway obstruction in the neonate due to airway abnormality", "[LA75.1] Agenesis of lung\n Def: This refers to the absence or rudimentary residua of an undeveloped lung....\n --PARENT--> [LA75] Structural developmental anomalies of lungs\n Def: Any condition caused by failure of the lungs to correctly develop during the antenatal period....\n --CHILD--> [LA75.1] Agenesis of lung\n Def: This refers to the absence or rudimentary residua of an undeveloped lung....", "[LA75.1] Agenesis of lung\n Def: This refers to the absence or rudimentary residua of an undeveloped lung....\n --PARENT--> [LA75] Structural developmental anomalies of lungs\n Def: Any condition caused by failure of the lungs to correctly develop during the antenatal period....\n --PARENT--> [?] Structural developmental anomalies of the respiratory system", "[CA40.Z] Pneumonia, organism unspecified\n --PARENT--> [CA40] Pneumonia\n Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ...\n --RELATED_TO--> [?] Congenital pneumonia\n Def: Congenital pneumonia is an acute respiratory infection contracted prenatally or during the intrapartum period that is caused by a virus, bacteria, or fungi....", "[CA40.Z] Pneumonia, organism unspecified\n --PARENT--> [CA40] Pneumonia\n Def: A disease of the lungs, frequently but not always caused by an infection with bacteria, virus, fungus, or parasite. This disease is characterised by fever, chills, cough with sputum production, chest ...\n --CHILD--> [CA40.1] Viral pneumonia\n Def: A disease of the pulmonary system, caused by an infection with a viral source. This disease is characterised by fever, lethargy, headache, myalgia, vomiting, or coughing. Transmission is by inhalation..." ]	CB40.Y	Other specified diseases of the respiratory system	[ { "from_icd11": "LA75.1", "icd10_code": "Q333", "icd10_title": "Agenesis of lung" }, { "from_icd11": "CA40.Z", "icd10_code": "J189", "icd10_title": "Pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J181", "icd10_title": "Lobar pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J188", "icd10_title": "Other pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J168", "icd10_title": "Pneumonia due to other specified infectious organisms" }, { "from_icd11": "CA40.Z", "icd10_code": "J180", "icd10_title": "Bronchopneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J17", "icd10_title": "Pneumonia in diseases classified elsewhere" }, { "from_icd11": "CA40.Z", "icd10_code": "J182", "icd10_title": "Hypostatic pneumonia, unspecified organism" }, { "from_icd11": "CA40.Z", "icd10_code": "J16", "icd10_title": "Pneumonia due to other infectious organisms, not elsewhere classified" }, { "from_icd11": "CA40.Z", "icd10_code": "J171", "icd10_title": "" }, { "from_icd11": "CA40.Z", "icd10_code": "J173", "icd10_title": "" }, { "from_icd11": "CA40.Z", "icd10_code": "J178", "icd10_title": "" }, { "from_icd11": "CA40.Z", "icd10_code": "J18", "icd10_title": "Pneumonia, unspecified organism" }, { "from_icd11": "CB41", "icd10_code": "J9622", "icd10_title": "Acute and chronic respiratory failure with hypercapnia" }, { "from_icd11": "CB41", "icd10_code": "J9620", "icd10_title": "Acute and chronic respiratory failure, unspecified whether with hypoxia or hypercapnia" } ]	Q333	Agenesis of lung
In the United States, renal cell carcinoma (RCC) has incidence in excess of 30,000 cases, with 12,000 deaths every year from the disease . It occurs predominantly in males in their sixth to eight decade of life, and African Americans have a 10-20% higher incidence . RCC is well known for its ability to metastasize to nearly every organ system of the body. Metastasis usually occurs several years after identification of the renal primary, but up to 30% of patients have metastatic disease on initial presentation . The most common targets for metastases are lung, bone, lymph nodes, adrenal glands, brain, liver, and contralateral kidney . In contrast, pancreatic and cutaneous involvement is exceedingly rare, occurring approximately 0.25-3% and 3.3% of the time, respectively . Metastatic RCC is typically classified as either synchronous (detected at the same time as primary tumors) or metachronous (detected after a time interval from primary tumor, normally >6 months). In fact, it is not uncommon for metastatic pancreatic lesions to develop several years after nephrectomy . RCC with pancreatic involvement can be a diagnostic challenge in differentiating between primary pancreatic cancer and metastatic disease. Our case exemplifies this diagnostic difficulty as the patient developed subcutaneous, pancreatic and parotid gland metastatic foci of RCC without ever having developed evidence of a renal primary.	4.3125	0.827148	sec[0]/p[0]	en	0.999995	20302679	https://doi.org/10.1186/1477-7819-8-18	[ "metastatic", "pancreatic", "renal", "time", "incidence", "every", "occurs", "several", "involvement", "united" ]	[ { "code": "2D4Z", "title": "Unspecified malignant neoplasms of unspecified sites" }, { "code": "5C64.5", "title": "Disorders of calcium metabolism" }, { "code": "2E2Z", "title": "Malignant neoplasm metastasis, unspecified" }, { "code": "2E03", "title": "Malignant neoplasm metastasis in bone or bone marrow" }, { "code": "2D70", "title": "Malignant neoplasm metastasis in lung" }, { "code": "DC3Z", "title": "Diseases of pancreas, unspecified" }, { "code": "DC3Y", "title": "Other specified diseases of pancreas" }, { "code": "LB21.3", "title": "Agenesis-aplasia of pancreas" }, { "code": "LB21.Z", "title": "Structural developmental anomalies of pancreas, unspecified" }, { "code": "DC35.0", "title": "Atrophy of pancreas" } ]	=== ICD-11 CODES FOUND === [2D4Z] Unspecified malignant neoplasms of unspecified sites Also known as: Unspecified malignant neoplasms of unspecified sites \| malignancy of unspecified site \| malignancy unspecified primary site \| malignant growth of unspecified site \| malignant mass of unspecified site [5C64.5] Disorders of calcium metabolism Definition: This refers to disorders in the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcaemia or hypocalcaemia, both of which can have important consequences for health. Also known as: Disorders of calcium metabolism \| Calcinosis \| general calcification \| heterotopic calcification \| metastatic calcification Excludes: Hyperparathyroidism \| Chondrocalcinosis [2E2Z] Malignant neoplasm metastasis, unspecified Also known as: Malignant neoplasm metastasis, unspecified \| secondary malignant neoplasm \| metastasis \| metastases \| disseminated metastases [2E03] Malignant neoplasm metastasis in bone or bone marrow Definition: The spread of a malignant neoplasm from a primary site to the skeletal system. The majority of metastatic neoplasms to the bone are carcinomas. Also known as: Malignant neoplasm metastasis in bone or bone marrow \| bone metastasis \| bony metastasis \| osseous metastasis \| secondary cancer of bone [2D70] Malignant neoplasm metastasis in lung Also known as: Malignant neoplasm metastasis in lung \| metastasis in lung \| pulmonary metastasis \| secondary cancer in lung \| secondary malignant tumour in lung Excludes: Malignant neoplasms of bronchus or lung [DC3Z] Diseases of pancreas, unspecified Also known as: Diseases of pancreas, unspecified [DC3Y] Other specified diseases of pancreas Also known as: Other specified diseases of pancreas \| Calculus of pancreas \| pancreas calculi \| pancreas duct calculus \| pancreas duct lithiasis [LB21.3] Agenesis-aplasia of pancreas Definition: This refers to the failure of an organ to develop during embryonic growth and development due to the absence of primordial tissue of the pancreas. Also known as: Agenesis-aplasia of pancreas \| Congenital absence of pancreas \| Congenital pancreas absence \| Congenital pancreatic absence \| Absent pancreas [LB21.Z] Structural developmental anomalies of pancreas, unspecified Also known as: Structural developmental anomalies of pancreas, unspecified \| Structural developmental anomalies of pancreas \| malformations of pancreas \| anomalies of pancreas \| congenital abnormality of pancreas [DC35.0] Atrophy of pancreas Also known as: Atrophy of pancreas \| pancreatic atrophy \| pancreas ductal atrophy === GRAPH WALKS === --- Walk 1 --- [2D4Z] Unspecified malignant neoplasms of unspecified sites --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites --EXCLUDES--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --- Walk 2 --- [2D4Z] Unspecified malignant neoplasms of unspecified sites --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites --CHILD--> [2D41] Unspecified carcinoma of unspecified site --- Walk 3 --- [5C64.5] Disorders of calcium metabolism Def: This refers to disorders in the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcaemia or hypocalcaemia, both of which can have important ... --EXCLUDES--> [?] Chondrocalcinosis Def: Chondrocalcinosis refers to radiographic calcification in hyaline and/or fibrocartilage and is not specific for CPPD or other particular crystal deposition disease. Familial l CPPD deposition disease ... --PARENT--> [?] Certain specified crystal arthropathies --- Walk 4 --- [5C64.5] Disorders of calcium metabolism Def: This refers to disorders in the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcaemia or hypocalcaemia, both of which can have important ... --RELATED_TO--> [?] Familial hypocalciuric hypercalcaemia Def: Familial Hypocalciuric Hypercalcaemia (FHH) or benign familial hypercalcaemia is an autosomal dominant disorder of calcium metabolism that is often asymptomatic and that is biologically characterised ... --PARENT--> [?] Interstitial lung diseases associated with metabolic diseases Def: Interstitial lung diseases associated with metabolic diseases refers to a group of lung diseases affecting the interstitium (the tissue and space around the air sacs of the lungs). This diagnosis is a... --- Walk 5 --- [2E2Z] Malignant neoplasm metastasis, unspecified --PARENT--> [?] Malignant neoplasm metastases Def: Spread of a malignant neoplasm into secondary sites.... --CHILD--> [2D50] Malignant neoplasm metastasis in brain Def: A malignant neoplasm that has spread to the brain from another anatomic site or system. The majority are carcinomas (usually lung or breast carcinomas).... --- Walk 6 --- [2E2Z] Malignant neoplasm metastasis, unspecified --PARENT--> [?] Malignant neoplasm metastases Def: Spread of a malignant neoplasm into secondary sites.... --CHILD--> [2D51] Malignant neoplasm metastasis in meninges	[ "[2D4Z] Unspecified malignant neoplasms of unspecified sites\n --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites\n --EXCLUDES--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...", "[2D4Z] Unspecified malignant neoplasms of unspecified sites\n --PARENT--> [?] Malignant neoplasms of ill-defined or unspecified primary sites\n --CHILD--> [2D41] Unspecified carcinoma of unspecified site", "[5C64.5] Disorders of calcium metabolism\n Def: This refers to disorders in the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcaemia or hypocalcaemia, both of which can have important ...\n --EXCLUDES--> [?] Chondrocalcinosis\n Def: Chondrocalcinosis refers to radiographic calcification in hyaline and/or fibrocartilage and is not specific for CPPD or other particular crystal deposition disease. Familial l CPPD deposition disease ...\n --PARENT--> [?] Certain specified crystal arthropathies", "[5C64.5] Disorders of calcium metabolism\n Def: This refers to disorders in the mechanism by which the body maintains adequate calcium levels. Derangements of this mechanism lead to hypercalcaemia or hypocalcaemia, both of which can have important ...\n --RELATED_TO--> [?] Familial hypocalciuric hypercalcaemia\n Def: Familial Hypocalciuric Hypercalcaemia (FHH) or benign familial hypercalcaemia is an autosomal dominant disorder of calcium metabolism that is often asymptomatic and that is biologically characterised ...\n --PARENT--> [?] Interstitial lung diseases associated with metabolic diseases\n Def: Interstitial lung diseases associated with metabolic diseases refers to a group of lung diseases affecting the interstitium (the tissue and space around the air sacs of the lungs). This diagnosis is a...", "[2E2Z] Malignant neoplasm metastasis, unspecified\n --PARENT--> [?] Malignant neoplasm metastases\n Def: Spread of a malignant neoplasm into secondary sites....\n --CHILD--> [2D50] Malignant neoplasm metastasis in brain\n Def: A malignant neoplasm that has spread to the brain from another anatomic site or system. The majority are carcinomas (usually lung or breast carcinomas)....", "[2E2Z] Malignant neoplasm metastasis, unspecified\n --PARENT--> [?] Malignant neoplasm metastases\n Def: Spread of a malignant neoplasm into secondary sites....\n --CHILD--> [2D51] Malignant neoplasm metastasis in meninges" ]	2D4Z	Unspecified malignant neoplasms of unspecified sites	[ { "from_icd11": "2D4Z", "icd10_code": "C802", "icd10_title": "Malignant neoplasm associated with transplanted organ" }, { "from_icd11": "2D4Z", "icd10_code": "C7650", "icd10_title": "Malignant neoplasm of unspecified lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7642", "icd10_title": "Malignant neoplasm of left upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7640", "icd10_title": "Malignant neoplasm of unspecified upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7652", "icd10_title": "Malignant neoplasm of left lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7651", "icd10_title": "Malignant neoplasm of right lower limb" }, { "from_icd11": "2D4Z", "icd10_code": "C7641", "icd10_title": "Malignant neoplasm of right upper limb" }, { "from_icd11": "2D4Z", "icd10_code": "C801", "icd10_title": "Malignant (primary) neoplasm, unspecified" }, { "from_icd11": "2D4Z", "icd10_code": "C768", "icd10_title": "Malignant neoplasm of other specified ill-defined sites" }, { "from_icd11": "2D4Z", "icd10_code": "C761", "icd10_title": "Malignant neoplasm of thorax" }, { "from_icd11": "2D4Z", "icd10_code": "C762", "icd10_title": "Malignant neoplasm of abdomen" }, { "from_icd11": "2D4Z", "icd10_code": "C763", "icd10_title": "Malignant neoplasm of pelvis" }, { "from_icd11": "2D4Z", "icd10_code": "C800", "icd10_title": "Disseminated malignant neoplasm, unspecified" }, { "from_icd11": "2D4Z", "icd10_code": "C76-C80", "icd10_title": "" }, { "from_icd11": "2D4Z", "icd10_code": "C76", "icd10_title": "Malignant neoplasm of other and ill-defined sites" } ]	C802	Malignant neoplasm associated with transplanted organ
Case reports have linked generalized pruritus to almost every type of malignancy. In the absence of clinically evident lymphadenopathy as in our patient's case, physicians are more likely to order diagnostic workup directed towards MM due to patient's advanced age. However, pruritus as a manifestation of MM is exceedingly rare. It has been described in a few cases and when myeloma is associated with liver disease, amyloidosis, and renal disease . On the other hand, persistent generalized pruritus may be seen in up to 30% of patients with HL, particularly the nodular sclerosing type with mediastinal mass . It may predate the diagnosis by up to 5 years and was considered a B symptom from 1965 to 1971. Fever replaced pruritus as a B symptom as the latter did not have a predictable impact on survival . From a diagnostic point, increased plasma cells in the bone marrow may be seen with HL irrespective of the stage of the disease and is considered reactive, but significant bone marrow plasmacytosis is suspicious for concurrent MM . Although the initial outpatient workup for pruritus in our patient led to the diagnosis of MM, the chief complaint resolved only after diagnosis and treatment of lymphoma. Despite its rarity, it is important for physicians to consider the possibility of concurrent HL and MM particularly in older patients who present with symptoms such as pruritus that are atypical for myeloma.	4.144531	0.671875	sec[2]/p[1]	en	0.999997	24027647	https://doi.org/10.1155/2013/398769	[ "pruritus", "type", "physicians", "workup", "myeloma", "patients", "particularly", "considered", "bone", "marrow" ]	[ { "code": "EC90.Z", "title": "Pruritus, unspecified" }, { "code": "JA65.11", "title": "Pruritus of pregnancy" }, { "code": "ME65.1", "title": "Itching of skin" }, { "code": "EG60", "title": "Anal pruritus" }, { "code": "EC90.10", "title": "Uraemic pruritus" }, { "code": "9C82.4", "title": "Oculomotor apraxia" }, { "code": "ED50.Z", "title": "Ichthyosis of unspecified type" }, { "code": "EH6Z", "title": "Drug eruption of unspecified type" }, { "code": "5C51.3", "title": "Glycogen storage disease" }, { "code": "LD20.1", "title": "Syndromes with lissencephaly as a major feature" } ]	=== ICD-11 CODES FOUND === [EC90.Z] Pruritus, unspecified Also known as: Pruritus, unspecified \| Pruritus [JA65.11] Pruritus of pregnancy Definition: Pruritus in pregnancy can usually be attributed to a specific cause such as cholestasis, a pregnancy-specific dermatosis such as pruritic urticarial papules and plaques of pregnancy, or to exacerbation of a preexisting inflammatory dermatosis such as atopic eczema. Not uncommonly, however, a specific cause cannot be identified. Also known as: Pruritus of pregnancy \| Pruritus gravidarum [ME65.1] Itching of skin Definition: The sensation of itch in the skin. For persistent itch of unknown cause the term "Pruritus of unknown cause" should be used. Also known as: Itching of skin \| Pruritus of unspecified aetiology [EG60] Anal pruritus Definition: Anal pruritus is irritation of the skin at the anal margin and surrounding perianal skin which results in the desire to scratch. Also known as: Anal pruritus \| Pruritus ani \| Perianal itching [EC90.10] Uraemic pruritus Definition: Pruritus in patients with chronic renal failure. Although common in untreated chronic kidney disease, it is particularly prevalent in patients receiving peritoneal or haemo-dialysis. The itch is not due to elevated serum urea levels. The precise mechanisms are not fully understood. Also known as: Uraemic pruritus \| Nephrogenic pruritus \| Pruritus due to chronic kidney disease \| Renal pruritus [9C82.4] Oculomotor apraxia Also known as: Oculomotor apraxia \| Congenital ocular motor apraxia \| Cogan’s congenital ocular motor apraxia \| Saccadic palsy \| Head thrust movement [ED50.Z] Ichthyosis of unspecified type Also known as: Ichthyosis of unspecified type \| Ichthyoses [EH6Z] Drug eruption of unspecified type Also known as: Drug eruption of unspecified type \| Drug-induced eruptions \| drug eruption or rash of unspecified type \| rash due to drug NOS \| drug rash [5C51.3] Glycogen storage disease Definition: The term Glycogen storage disease characterises a group of heterogeneous diseases resulting from defects in the process of glycogen synthesis or breakdown within muscles, liver, and other cell types. Also known as: Glycogen storage disease \| Glycogenosis \| GSD - [Glycogen storage disease] \| glycogen thesaurismosis \| diffuse glycogenosis Includes: Glycogen storage disease due to LAMP-2 deficiency \| Glycogen storage disease due to glycogen debranching enzyme deficiency \| Glycogen storage disease due to muscle glycogen phosphorylase deficiency [LD20.1] Syndromes with lissencephaly as a major feature Definition: The term lissencephaly covers a group of rare malformations sharing the common feature of anomalies in the appearance of brain convolutions (characterised by simplification or absence of folding) associated with abnormal organisation of the cortical layers as a result of neuronal migration defects during embryogenesis. Children with lissencephaly have feeding and swallowing problems, muscle tone anomalies (early hypotonia and subsequently limb hypertonia), seizures (in particular, infantile spas Also known as: Syndromes with lissencephaly as a major feature \| Pachygyria \| Agyria \| Classic lissencephaly \| Lissencephaly type 1 Includes: Agyria \| Pachygyria === GRAPH WALKS === --- Walk 1 --- [EC90.Z] Pruritus, unspecified --PARENT--> [EC90] Pruritus Def: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.... --CHILD--> [EC90.1] Pruritus due to systemic disorder Def: Pruritus due to underlying systemic disorder such as renal failure or cholestatic jaundice.... --- Walk 2 --- [EC90.Z] Pruritus, unspecified --PARENT--> [EC90] Pruritus Def: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.... --CHILD--> [EC90.0] Pruritus due to skin disorder Def: Pruritus due to skin disorder, especially those such as xerosis cutis or psoriasis where itch may occur but is not an inherent component of the disorder.... --- Walk 3 --- [JA65.11] Pruritus of pregnancy Def: Pruritus in pregnancy can usually be attributed to a specific cause such as cholestasis, a pregnancy-specific dermatosis such as pruritic urticarial papules and plaques of pregnancy, or to exacerbatio... --RELATED_TO--> [?] Intrahepatic cholestasis of pregnancy Def: Intrahepatic cholestasis of pregnancy (ICP) is a cholestatic disorder characterised by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum aminotransferases and ... --CHILD--> [?] Cholestatic pruritus of pregnancy --- Walk 4 --- [JA65.11] Pruritus of pregnancy Def: Pruritus in pregnancy can usually be attributed to a specific cause such as cholestasis, a pregnancy-specific dermatosis such as pruritic urticarial papules and plaques of pregnancy, or to exacerbatio... --RELATED_TO--> [?] Intrahepatic cholestasis of pregnancy Def: Intrahepatic cholestasis of pregnancy (ICP) is a cholestatic disorder characterised by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum aminotransferases and ... --CHILD--> [?] Cholestatic pruritus of pregnancy --- Walk 5 --- [ME65.1] Itching of skin Def: The sensation of itch in the skin. For persistent itch of unknown cause the term "Pruritus of unknown cause" should be used.... --PARENT--> [ME65] Disturbances of skin sensation of unspecified aetiology Def: A group of cutaneous symptoms for which it is frequently impossible to identify a precise cause.... --RELATED_TO--> [?] Anaesthesia of skin Def: Partial or complete loss of sensation affecting the skin, most commonly affecting a circumscribed area and resulting from sensory nerve damage as from injury or leprosy.... --- Walk 6 --- [ME65.1] Itching of skin Def: The sensation of itch in the skin. For persistent itch of unknown cause the term "Pruritus of unknown cause" should be used.... --PARENT--> [ME65] Disturbances of skin sensation of unspecified aetiology Def: A group of cutaneous symptoms for which it is frequently impossible to identify a precise cause.... --CHILD--> [ME65.1] Itching of skin Def: The sensation of itch in the skin. For persistent itch of unknown cause the term "Pruritus of unknown cause" should be used....	[ "[EC90.Z] Pruritus, unspecified\n --PARENT--> [EC90] Pruritus\n Def: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief....\n --CHILD--> [EC90.1] Pruritus due to systemic disorder\n Def: Pruritus due to underlying systemic disorder such as renal failure or cholestatic jaundice....", "[EC90.Z] Pruritus, unspecified\n --PARENT--> [EC90] Pruritus\n Def: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief....\n --CHILD--> [EC90.0] Pruritus due to skin disorder\n Def: Pruritus due to skin disorder, especially those such as xerosis cutis or psoriasis where itch may occur but is not an inherent component of the disorder....", "[JA65.11] Pruritus of pregnancy\n Def: Pruritus in pregnancy can usually be attributed to a specific cause such as cholestasis, a pregnancy-specific dermatosis such as pruritic urticarial papules and plaques of pregnancy, or to exacerbatio...\n --RELATED_TO--> [?] Intrahepatic cholestasis of pregnancy\n Def: Intrahepatic cholestasis of pregnancy (ICP) is a cholestatic disorder characterised by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum aminotransferases and ...\n --CHILD--> [?] Cholestatic pruritus of pregnancy", "[JA65.11] Pruritus of pregnancy\n Def: Pruritus in pregnancy can usually be attributed to a specific cause such as cholestasis, a pregnancy-specific dermatosis such as pruritic urticarial papules and plaques of pregnancy, or to exacerbatio...\n --RELATED_TO--> [?] Intrahepatic cholestasis of pregnancy\n Def: Intrahepatic cholestasis of pregnancy (ICP) is a cholestatic disorder characterised by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum aminotransferases and ...\n --CHILD--> [?] Cholestatic pruritus of pregnancy", "[ME65.1] Itching of skin\n Def: The sensation of itch in the skin. For persistent itch of unknown cause the term \"Pruritus of unknown cause\" should be used....\n --PARENT--> [ME65] Disturbances of skin sensation of unspecified aetiology\n Def: A group of cutaneous symptoms for which it is frequently impossible to identify a precise cause....\n --RELATED_TO--> [?] Anaesthesia of skin\n Def: Partial or complete loss of sensation affecting the skin, most commonly affecting a circumscribed area and resulting from sensory nerve damage as from injury or leprosy....", "[ME65.1] Itching of skin\n Def: The sensation of itch in the skin. For persistent itch of unknown cause the term \"Pruritus of unknown cause\" should be used....\n --PARENT--> [ME65] Disturbances of skin sensation of unspecified aetiology\n Def: A group of cutaneous symptoms for which it is frequently impossible to identify a precise cause....\n --CHILD--> [ME65.1] Itching of skin\n Def: The sensation of itch in the skin. For persistent itch of unknown cause the term \"Pruritus of unknown cause\" should be used...." ]	EC90.Z	Pruritus, unspecified	[ { "from_icd11": "EC90.Z", "icd10_code": "L298", "icd10_title": "Other pruritus" }, { "from_icd11": "EC90.Z", "icd10_code": "L299", "icd10_title": "Pruritus, unspecified" }, { "from_icd11": "EC90.Z", "icd10_code": "L29", "icd10_title": "Pruritus" }, { "from_icd11": "JA65.11", "icd10_code": "O26852", "icd10_title": "Spotting complicating pregnancy, second trimester" }, { "from_icd11": "JA65.11", "icd10_code": "O26892", "icd10_title": "Other specified pregnancy related conditions, second trimester" }, { "from_icd11": "JA65.11", "icd10_code": "O26893", "icd10_title": "Other specified pregnancy related conditions, third trimester" }, { "from_icd11": "JA65.11", "icd10_code": "O26873", "icd10_title": "Cervical shortening, third trimester" }, { "from_icd11": "JA65.11", "icd10_code": "O26833", "icd10_title": "Pregnancy related renal disease, third trimester" }, { "from_icd11": "JA65.11", "icd10_code": "O26891", "icd10_title": "Other specified pregnancy related conditions, first trimester" }, { "from_icd11": "JA65.11", "icd10_code": "O26872", "icd10_title": "Cervical shortening, second trimester" }, { "from_icd11": "JA65.11", "icd10_code": "O26832", "icd10_title": "Pregnancy related renal disease, second trimester" }, { "from_icd11": "JA65.11", "icd10_code": "O26853", "icd10_title": "Spotting complicating pregnancy, third trimester" }, { "from_icd11": "JA65.11", "icd10_code": "O2686", "icd10_title": "Pruritic urticarial papules and plaques of pregnancy (PUPPP)" }, { "from_icd11": "JA65.11", "icd10_code": "O26843", "icd10_title": "Uterine size-date discrepancy, third trimester" }, { "from_icd11": "JA65.11", "icd10_code": "O26823", "icd10_title": "Pregnancy related peripheral neuritis, third trimester" } ]	L298	Other pruritus
A 36-year-old cachectic female (body weight was 41.2 kg and height was 1.62 m), previously diagnosed with adenocarcinoma of the ampulla of Vater that invades the pancreas (pT4N0 stage), which was surgically removed (cephalic duodenopancreatectomy, radical surgery) 8 months ago, was admitted to our hospital with pale skin, scleral jaundice, sudden onset of severe abdominal pain and cramping, vomiting, diarrhea, and subfebrility. No alcohol, tobacco, or other drug use was declared. Before and after surgery and also before adjuvant therapy, no comorbidities were diagnosed, and the general status was carefully assessed without modification. Two months following surgery, she underwent five chemotherapy cycles with a combined regimen that included oral capecitabine and intravenous oxaliplatin (CAPOX or XELOX). CAPOX regimen comprised administration of 150 mg/m 2 of oxaliplatin (diluted in a 5% glucose solution) intravenously over 120 min on Day 1, and then 1250 mg/m 2 of oral capecitabine administered twice daily from Days 1 to 14, followed by 1-week drug holiday, in a 21-day cycle. The last (fifth) cycle was stopped 1 month before the present admission. The reason for choosing this aggressive regimen was the patients’ age and good pre-chemotherapy general status. There were no significant acute toxicity-related disorders, except slight diarrhea and vomiting, either of which recurred before this episode.	3.919922	0.973633	sec[1]/p[0]	en	0.999998	24041405	https://doi.org/10.1186/1746-1596-8-150	[ "regimen", "diagnosed", "that", "which", "vomiting", "diarrhea", "drug", "general", "status", "chemotherapy" ]	[ { "code": "QC49", "title": "Personal history of noncompliance with medical treatment or regimen" }, { "code": "QB97", "title": "Contact with health services for chemotherapy session for neoplasm" }, { "code": "QB9Y", "title": "Other specified contact with health services for nonsurgical interventions not involving devices" }, { "code": "1F45", "title": "Malaria without parasitological confirmation" }, { "code": "RA01.1", "title": "COVID-19, virus not identified" }, { "code": "8A80.Z", "title": "Migraine, unspecified" }, { "code": "QA76", "title": "Medication or substance that is known to be an allergen without injury or harm" }, { "code": "PL13.6", "title": "Medication or substance that is known to be an allergen, as mode of injury or harm" }, { "code": "9C40.A0", "title": "Papilloedema" }, { "code": "PA6Z", "title": "Unintentional fall from unspecified height" } ]	=== ICD-11 CODES FOUND === [QC49] Personal history of noncompliance with medical treatment or regimen Also known as: Personal history of noncompliance with medical treatment or regimen \| history of noncompliance with medical treatment or regimen \| compliance or being ill problem \| Personal noncompliance with dietary regimen \| Personal noncompliance with renal dialysis [QB97] Contact with health services for chemotherapy session for neoplasm Also known as: Contact with health services for chemotherapy session for neoplasm \| antineoplastic chemotherapy regimen \| cancer chemotherapy regimen \| maintenance chemotherapy for neoplasm \| neoplasm chemotherapy [QB9Y] Other specified contact with health services for nonsurgical interventions not involving devices Also known as: Other specified contact with health services for nonsurgical interventions not involving devices \| Chemotherapy other than for neoplasm \| admission for chemotherapy administration other than for neoplasm \| chemotherapy regimen other than for neoplasm \| drug therapy other than for neoplasm [1F45] Malaria without parasitological confirmation Definition: Clinically diagnosed malaria without parasitological confirmation Also known as: Malaria without parasitological confirmation \| marsh fever \| remittent congestive fever \| coastal fever \| remittent gastric fever Includes: clinically diagnosed malaria without parasitological confirmation [RA01.1] COVID-19, virus not identified Also known as: COVID-19, virus not identified \| clinically diagnosed COVID-19 \| suspected COVID-19 \| probable COVID-19 \| clinical COVID-19 Excludes: COVID-19, virus identified \| Coronavirus infection, unspecified site \| Special screening examination for other viral diseases [8A80.Z] Migraine, unspecified Also known as: Migraine, unspecified \| Migraine [QA76] Medication or substance that is known to be an allergen without injury or harm Definition: Medication that has previously been identified as an allergen to the patient is administered, but does not result in injury or harm. Also known as: Medication or substance that is known to be an allergen without injury or harm Excludes: Medication or substance that is known to be an allergen, as mode of injury or harm [PL13.6] Medication or substance that is known to be an allergen, as mode of injury or harm Also known as: Medication or substance that is known to be an allergen, as mode of injury or harm \| medication error relating to known allergy to drug or substance \| adverse drug event relating to known allergy to drug or substance [9C40.A0] Papilloedema Definition: Optic disc swelling that results from increased intracranial pressure Also known as: Papilloedema \| Optic disc swelling that results from increased intracranial pressure Includes: Optic disc swelling that results from increased intracranial pressure [PA6Z] Unintentional fall from unspecified height Also known as: Unintentional fall from unspecified height \| fall NOS \| accidental fall \| fall causing injury that resulted in death \| fell NOS === GRAPH WALKS === --- Walk 1 --- [QC49] Personal history of noncompliance with medical treatment or regimen --PARENT--> [?] Personal history of health problems --CHILD--> [QC41] Personal history of non-malignant neoplasms --- Walk 2 --- [QC49] Personal history of noncompliance with medical treatment or regimen --PARENT--> [?] Personal history of health problems --CHILD--> [QC42] Personal history of infectious or parasitic diseases --- Walk 3 --- [QB97] Contact with health services for chemotherapy session for neoplasm --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices --CHILD--> [QB90] Contact with health services for ear piercing --- Walk 4 --- [QB97] Contact with health services for chemotherapy session for neoplasm --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices --CHILD--> [QB91] Contact with health services for piercing of body site other than ear --- Walk 5 --- [QB9Y] Other specified contact with health services for nonsurgical interventions not involving devices --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices --CHILD--> [QB92] Contact with health services for issue of repeat prescription --- Walk 6 --- [QB9Y] Other specified contact with health services for nonsurgical interventions not involving devices --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices --CHILD--> [QB92] Contact with health services for issue of repeat prescription	[ "[QC49] Personal history of noncompliance with medical treatment or regimen\n --PARENT--> [?] Personal history of health problems\n --CHILD--> [QC41] Personal history of non-malignant neoplasms", "[QC49] Personal history of noncompliance with medical treatment or regimen\n --PARENT--> [?] Personal history of health problems\n --CHILD--> [QC42] Personal history of infectious or parasitic diseases", "[QB97] Contact with health services for chemotherapy session for neoplasm\n --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices\n --CHILD--> [QB90] Contact with health services for ear piercing", "[QB97] Contact with health services for chemotherapy session for neoplasm\n --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices\n --CHILD--> [QB91] Contact with health services for piercing of body site other than ear", "[QB9Y] Other specified contact with health services for nonsurgical interventions not involving devices\n --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices\n --CHILD--> [QB92] Contact with health services for issue of repeat prescription", "[QB9Y] Other specified contact with health services for nonsurgical interventions not involving devices\n --PARENT--> [?] Contact with health services for nonsurgical interventions not involving devices\n --CHILD--> [QB92] Contact with health services for issue of repeat prescription" ]	QC49	Personal history of noncompliance with medical treatment or regimen	[ { "from_icd11": "QC49", "icd10_code": "Z91128", "icd10_title": "Patient's intentional underdosing of medication regimen for other reason" }, { "from_icd11": "QC49", "icd10_code": "Z9114", "icd10_title": "Patient's other noncompliance with medication regimen" }, { "from_icd11": "QC49", "icd10_code": "Z9111", "icd10_title": "Patient's noncompliance with dietary regimen" }, { "from_icd11": "QC49", "icd10_code": "Z9119", "icd10_title": "Patient's noncompliance with other medical treatment and regimen" }, { "from_icd11": "QC49", "icd10_code": "Z91138", "icd10_title": "Patient's unintentional underdosing of medication regimen for other reason" }, { "from_icd11": "QC49", "icd10_code": "Z91120", "icd10_title": "Patient's intentional underdosing of medication regimen due to financial hardship" }, { "from_icd11": "QC49", "icd10_code": "Z9115", "icd10_title": "Patient's noncompliance with renal dialysis" }, { "from_icd11": "QC49", "icd10_code": "Z91130", "icd10_title": "Patient's unintentional underdosing of medication regimen due to age-related debility" }, { "from_icd11": "QC49", "icd10_code": "Z911", "icd10_title": "Patient's noncompliance with medical treatment and regimen" }, { "from_icd11": "QB97", "icd10_code": "Z5111", "icd10_title": "Encounter for antineoplastic chemotherapy" }, { "from_icd11": "QB97", "icd10_code": "Z5112", "icd10_title": "Encounter for antineoplastic immunotherapy" }, { "from_icd11": "QB97", "icd10_code": "Z511", "icd10_title": "Encounter for antineoplastic chemotherapy and immunotherapy" }, { "from_icd11": "QB97", "icd10_code": "Z51", "icd10_title": "Encounter for other aftercare and medical care" }, { "from_icd11": "QB9Y", "icd10_code": "Z5181", "icd10_title": "Encounter for therapeutic drug level monitoring" }, { "from_icd11": "1F45", "icd10_code": "B54", "icd10_title": "Unspecified malaria" } ]	Z91128	Patient's intentional underdosing of medication regimen for other reason
A digital subtraction angiogram (DSA) was performed to further study the source of SAH. DSA revealed a large and tortuous anomalous vein originating in the right frontal area, traversing anteriorly and leftward into the left frontal region . It then entered the skull through an osseous channel within the frontal bone and exited through a bony opening above the left supraorbital foramen in the left forehead. A more comprehensive evaluation of the vein showed an anomalous extra-axial stand-alone vein, which was responsible for a significant portion of frontal venous drainage as was demonstrated in the venous phase of right internal carotid artery DSA runs. The vein did not have a direct connection to the superior sagittal sinus (SSS) anterior part, which was found to be hypoplastic either as a result or the cause of the drainage provided by the anomalous vein. The exact terminus of the vein could not be identified with certainty, but it seemed to drain into the left external jugular vein at the level of the parotid gland. Additionally, the patient had a small, near-vertical anterior frontal vein that appeared to be the draining portion of nasal mucosa into the venous confluence drained by the large anomalous frontal vein in lieu of the SSS, most consistent with the vein of foramen caecum . Small bilateral frontal veins connecting the orbital area with the anomalous venous confluence were also noted .	4.1875	0.578125	sec[1]/p[2]	en	0.999997	PMC9233433	https://doi.org/10.7759/cureus.25350	[ "vein", "frontal", "anomalous", "venous", "large", "area", "foramen", "which", "portion", "drainage" ]	[ { "code": "BD7Z", "title": "Diseases of veins, unspecified" }, { "code": "MC88", "title": "Prominent veins" }, { "code": "BD7Y", "title": "Other specified diseases of veins" }, { "code": "BD75.Y", "title": "Venous varicosities of other specified sites" }, { "code": "BD73.2Z", "title": "Systemic vein obstruction, unspecified" }, { "code": "9C82.4", "title": "Oculomotor apraxia" }, { "code": "CA0A.Y&XA91G8", "title": "Frontal sinus fistula" }, { "code": "CA0J.Y&XA91G8", "title": "Polyp of frontal sinus" }, { "code": "NA02.14", "title": "Fracture of frontal sinus of skull" }, { "code": "CA0C&XA91G8", "title": "Cyst of frontal sinus" } ]	=== ICD-11 CODES FOUND === [BD7Z] Diseases of veins, unspecified Also known as: Diseases of veins, unspecified [MC88] Prominent veins Also known as: Prominent veins [BD7Y] Other specified diseases of veins Also known as: Other specified diseases of veins [BD75.Y] Venous varicosities of other specified sites Also known as: Venous varicosities of other specified sites \| Caput medusae \| Jugular venous aneurysm \| jugular vein aneurysm \| Orbital varices [BD73.2Z] Systemic vein obstruction, unspecified Also known as: Systemic vein obstruction, unspecified \| Systemic vein obstruction [9C82.4] Oculomotor apraxia Also known as: Oculomotor apraxia \| Congenital ocular motor apraxia \| Cogan’s congenital ocular motor apraxia \| Saccadic palsy \| Head thrust movement [NA02.14] Fracture of frontal sinus of skull Also known as: Fracture of frontal sinus of skull \| fracture of frontal sinus \| frontal sinus bone fracture === GRAPH WALKS === --- Walk 1 --- [BD7Z] Diseases of veins, unspecified --PARENT--> [?] Diseases of veins --RELATED_TO--> [?] Venous complications in pregnancy --- Walk 2 --- [BD7Z] Diseases of veins, unspecified --PARENT--> [?] Diseases of veins --CHILD--> [BD72] Venous thromboembolism --- Walk 3 --- [MC88] Prominent veins --PARENT--> [?] Symptoms or signs involving the circulatory system --RELATED_TO--> [?] Fear of heart disease --- Walk 4 --- [MC88] Prominent veins --PARENT--> [?] Symptoms or signs involving the circulatory system --RELATED_TO--> [?] Fear of cardiovascular disease --- Walk 5 --- [BD7Y] Other specified diseases of veins --PARENT--> [?] Diseases of veins --RELATED_TO--> [?] Venous complications in pregnancy --- Walk 6 --- [BD7Y] Other specified diseases of veins --PARENT--> [?] Diseases of veins --RELATED_TO--> [?] Other venous complications following abortion, ectopic or molar pregnancy	[ "[BD7Z] Diseases of veins, unspecified\n --PARENT--> [?] Diseases of veins\n --RELATED_TO--> [?] Venous complications in pregnancy", "[BD7Z] Diseases of veins, unspecified\n --PARENT--> [?] Diseases of veins\n --CHILD--> [BD72] Venous thromboembolism", "[MC88] Prominent veins\n --PARENT--> [?] Symptoms or signs involving the circulatory system\n --RELATED_TO--> [?] Fear of heart disease", "[MC88] Prominent veins\n --PARENT--> [?] Symptoms or signs involving the circulatory system\n --RELATED_TO--> [?] Fear of cardiovascular disease", "[BD7Y] Other specified diseases of veins\n --PARENT--> [?] Diseases of veins\n --RELATED_TO--> [?] Venous complications in pregnancy", "[BD7Y] Other specified diseases of veins\n --PARENT--> [?] Diseases of veins\n --RELATED_TO--> [?] Other venous complications following abortion, ectopic or molar pregnancy" ]	BD7Z	Diseases of veins, unspecified	[ { "from_icd11": "BD7Z", "icd10_code": "I82412", "icd10_title": "Acute embolism and thrombosis of left femoral vein" }, { "from_icd11": "BD7Z", "icd10_code": "I82621", "icd10_title": "Acute embolism and thrombosis of deep veins of right upper extremity" }, { "from_icd11": "BD7Z", "icd10_code": "I82432", "icd10_title": "Acute embolism and thrombosis of left popliteal vein" }, { "from_icd11": "BD7Z", "icd10_code": "I82C11", "icd10_title": "Acute embolism and thrombosis of right internal jugular vein" }, { "from_icd11": "BD7Z", "icd10_code": "I82441", "icd10_title": "Acute embolism and thrombosis of right tibial vein" }, { "from_icd11": "BD7Z", "icd10_code": "I82422", "icd10_title": "Acute embolism and thrombosis of left iliac vein" }, { "from_icd11": "BD7Z", "icd10_code": "I82622", "icd10_title": "Acute embolism and thrombosis of deep veins of left upper extremity" }, { "from_icd11": "BD7Z", "icd10_code": "I824Z1", "icd10_title": "Acute embolism and thrombosis of unspecified deep veins of right distal lower extremity" }, { "from_icd11": "BD7Z", "icd10_code": "I82401", "icd10_title": "Acute embolism and thrombosis of unspecified deep veins of right lower extremity" }, { "from_icd11": "BD7Z", "icd10_code": "I824Z2", "icd10_title": "Acute embolism and thrombosis of unspecified deep veins of left distal lower extremity" }, { "from_icd11": "BD7Z", "icd10_code": "I82612", "icd10_title": "Acute embolism and thrombosis of superficial veins of left upper extremity" }, { "from_icd11": "BD7Z", "icd10_code": "I82721", "icd10_title": "Chronic embolism and thrombosis of deep veins of right upper extremity" }, { "from_icd11": "BD7Z", "icd10_code": "I82C12", "icd10_title": "Acute embolism and thrombosis of left internal jugular vein" }, { "from_icd11": "BD7Z", "icd10_code": "I82B12", "icd10_title": "Acute embolism and thrombosis of left subclavian vein" }, { "from_icd11": "BD7Z", "icd10_code": "I82421", "icd10_title": "Acute embolism and thrombosis of right iliac vein" } ]	I82412	Acute embolism and thrombosis of left femoral vein
A 10-year-old previously healthy girl with no prior remarkable medical history presented to our institution with fever following a one-week trip to Costa Rica. During this time, she stayed in a hotel in the rain forest where she took hikes with family members. She swam in the ocean as well as in chlorinated pools, saw many animals (including rodents), and was splashed with fresh water. Five days following her return from Costa Rica, she developed fever of one-week duration (up to 39.5°C), abdominal pain, nausea, and sore throat. None of the accompanying family members (parents and sibling) developed any signs of illness, nor was there any remarkable family history. The family resided in a metropolitan area in Los Angeles County, and there had been no recent floods or rodent exposures in the neighborhood preceding or following the trip. The patient was seen in her primary care physician's office one week into her illness. At that time, she had a negative throat beta streptococcus direct antigen screen. She developed bilateral eye pain and redness and was seen again by her primary care pediatrician two days later who performed further laboratory evaluations. Results included an alanine aminotransferase of 102 U/L, aspartate aminotransferase of 73 U/L, albumin 3.1 g/dL, total bilirubin 0.5 mg/dL, prothrombin time 12.9 seconds, partial thromboplastin time 38.1 seconds, and alkaline phosphatase 314 U/L.	3.855469	0.981934	sec[0]/p[0]	en	0.999996	22606527	https://doi.org/10.1155/2012/169013	[ "time", "family", "remarkable", "fever", "trip", "costa", "rica", "members", "pain", "throat" ]	[ { "code": "PL13.52", "title": "Incorrect timing of drug or medicament, as mode of injury" }, { "code": "QF2A", "title": "Difficulty or need for assistance with community participation" }, { "code": "MF50.1", "title": "Pollakiuria" }, { "code": "JA25.3", "title": "Eclampsia, time period unspecified" }, { "code": "KD3B.Z", "title": "Unspecified time of fetal death, cause not specified" }, { "code": "QE70.Z", "title": "Problems related to primary support group, including family circumstances, unspecified" }, { "code": "8C74.1Z", "title": "Periodic paralysis, unspecified" }, { "code": "2B90.Y", "title": "Other specified malignant neoplasms of colon" }, { "code": "EE61", "title": "Superficial fibromatoses" }, { "code": "9B70", "title": "Inherited retinal dystrophies" } ]	=== ICD-11 CODES FOUND === [PL13.52] Incorrect timing of drug or medicament, as mode of injury Also known as: Incorrect timing of drug or medicament, as mode of injury \| wrong timing of drug \| timing error in giving drug \| timing mistake in administration of drug \| administration error involving timing of drug Excludes: Problem with delayed treatment \| Overdose of substance, as mode of injury or harm [QF2A] Difficulty or need for assistance with community participation Also known as: Difficulty or need for assistance with community participation \| difficulty with community participation \| need for assistance with community participation \| need for assistance with community, social and civic life \| difficulty with community, social and civic life Includes: Lack of relaxation or leisure [MF50.1] Pollakiuria Also known as: Pollakiuria \| pollakisuria \| Daytime frequency of micturition [JA25.3] Eclampsia, time period unspecified Definition: Onset of convulsions in a woman with pre-eclampsia not attributable to other causes without a specific onset time. Also known as: Eclampsia, time period unspecified \| Eclampsia NOS \| eclamptic coma \| eclamptic toxaemia \| toxaemia with convulsions [KD3B.Z] Unspecified time of fetal death, cause not specified Also known as: Unspecified time of fetal death, cause not specified \| Fetal death, cause not specified \| stillbirth NOS \| stillborn NOS \| intrauterine fetal demise [QE70.Z] Problems related to primary support group, including family circumstances, unspecified Also known as: Problems related to primary support group, including family circumstances, unspecified \| Problems related to primary support group, including family circumstances \| family problem \| problem related to primary support group \| Problem related to gambling in the family [8C74.1Z] Periodic paralysis, unspecified Also known as: Periodic paralysis, unspecified \| Periodic paralysis \| Westphal disease \| periodic myotonia \| myoplegic dystrophy [2B90.Y] Other specified malignant neoplasms of colon Also known as: Other specified malignant neoplasms of colon \| Neuroendocrine neoplasm of colon \| Colon endocrine neoplasm \| Neuroendocrine carcinoma of colon \| NEC - [neuroendocrine carcinoma] of colon [EE61] Superficial fibromatoses Also known as: Superficial fibromatoses \| Pachydermodactyly \| Camptodactyly or streblodactyly \| Familial camptodactyly \| Sporadic camptodactyly [9B70] Inherited retinal dystrophies Also known as: Inherited retinal dystrophies \| hereditary retinal dystrophies \| Amaurosis - hypertrichosis \| Autosomal dominant late-onset retinal degeneration \| Bothnia retinal dystrophy Includes: Leber congenital amaurosis \| Stargardt disease \| Vitreoretinal dystrophy === GRAPH WALKS === --- Walk 1 --- [PL13.52] Incorrect timing of drug or medicament, as mode of injury --EXCLUDES--> [?] Overdose of substance, as mode of injury or harm Def: Incorrect dose - too high... --EXCLUDES--> [?] Unintentional exposure to or harmful effects of drugs, medicaments or biological substances --- Walk 2 --- [PL13.52] Incorrect timing of drug or medicament, as mode of injury --EXCLUDES--> [?] Delayed treatment --CHILD--> [?] Problem associated with delayed administration of a needed medication --- Walk 3 --- [QF2A] Difficulty or need for assistance with community participation --PARENT--> [?] Difficulty or need for assistance with activities Def: Identifies activities for which the person needs assistance or has such difficulty with, that it affects their need for health services or their treatment.... --CHILD--> [QF20] Difficulty or need for assistance with learning --- Walk 4 --- [QF2A] Difficulty or need for assistance with community participation --PARENT--> [?] Difficulty or need for assistance with activities Def: Identifies activities for which the person needs assistance or has such difficulty with, that it affects their need for health services or their treatment.... --CHILD--> [QF20] Difficulty or need for assistance with learning --- Walk 5 --- [MF50.1] Pollakiuria --PARENT--> [MF50] Abnormal micturition --CHILD--> [MF50.0] Frequent micturition Def: Needing to urinate more often than normal.... --- Walk 6 --- [MF50.1] Pollakiuria --PARENT--> [MF50] Abnormal micturition --CHILD--> [MF50.2] Urinary incontinence Def: Any condition of the urinary system, caused by determinants arising during the antenatal period or after birth, leading to loss of voluntary control or support of the urethra. These conditions are cha...	[ "[PL13.52] Incorrect timing of drug or medicament, as mode of injury\n --EXCLUDES--> [?] Overdose of substance, as mode of injury or harm\n Def: Incorrect dose - too high...\n --EXCLUDES--> [?] Unintentional exposure to or harmful effects of drugs, medicaments or biological substances", "[PL13.52] Incorrect timing of drug or medicament, as mode of injury\n --EXCLUDES--> [?] Delayed treatment\n --CHILD--> [?] Problem associated with delayed administration of a needed medication", "[QF2A] Difficulty or need for assistance with community participation\n --PARENT--> [?] Difficulty or need for assistance with activities\n Def: Identifies activities for which the person needs assistance or has such difficulty with, that it affects their need for health services or their treatment....\n --CHILD--> [QF20] Difficulty or need for assistance with learning", "[QF2A] Difficulty or need for assistance with community participation\n --PARENT--> [?] Difficulty or need for assistance with activities\n Def: Identifies activities for which the person needs assistance or has such difficulty with, that it affects their need for health services or their treatment....\n --CHILD--> [QF20] Difficulty or need for assistance with learning", "[MF50.1] Pollakiuria\n --PARENT--> [MF50] Abnormal micturition\n --CHILD--> [MF50.0] Frequent micturition\n Def: Needing to urinate more often than normal....", "[MF50.1] Pollakiuria\n --PARENT--> [MF50] Abnormal micturition\n --CHILD--> [MF50.2] Urinary incontinence\n Def: Any condition of the urinary system, caused by determinants arising during the antenatal period or after birth, leading to loss of voluntary control or support of the urethra. These conditions are cha..." ]	PL13.52	Incorrect timing of drug or medicament, as mode of injury	[ { "from_icd11": "QF2A", "icd10_code": "Z7389", "icd10_title": "Other problems related to life management difficulty" }, { "from_icd11": "QF2A", "icd10_code": "Z7382", "icd10_title": "Dual sensory impairment" }, { "from_icd11": "QF2A", "icd10_code": "Z73", "icd10_title": "Problems related to life management difficulty" }, { "from_icd11": "QF2A", "icd10_code": "Z732", "icd10_title": "Lack of relaxation and leisure" }, { "from_icd11": "QF2A", "icd10_code": "Z738", "icd10_title": "Other problems related to life management difficulty" }, { "from_icd11": "QF2A", "icd10_code": "Z739", "icd10_title": "Problem related to life management difficulty, unspecified" }, { "from_icd11": "MF50.1", "icd10_code": "R351", "icd10_title": "Nocturia" }, { "from_icd11": "MF50.1", "icd10_code": "R358", "icd10_title": "Other polyuria" }, { "from_icd11": "MF50.1", "icd10_code": "R35", "icd10_title": "Polyuria" }, { "from_icd11": "JA25.3", "icd10_code": "O159", "icd10_title": "Eclampsia, unspecified as to time period" }, { "from_icd11": "KD3B.Z", "icd10_code": "P95", "icd10_title": "Stillbirth" }, { "from_icd11": "QE70.Z", "icd10_code": "Z6379", "icd10_title": "Other stressful life events affecting family and household" }, { "from_icd11": "QE70.Z", "icd10_code": "Z6372", "icd10_title": "Alcoholism and drug addiction in family" }, { "from_icd11": "QE70.Z", "icd10_code": "Z638", "icd10_title": "Other specified problems related to primary support group" }, { "from_icd11": "QE70.Z", "icd10_code": "Z639", "icd10_title": "Problem related to primary support group, unspecified" } ]	Z7389	Other problems related to life management difficulty
From her clinical history, for purposes of retrospective study, our patient's presentation was not typical for a conventional urothelial carcinoma, as the mass was large while producing negative urine analysis and negative urine cytology results. Even though squamous cell carcinoma of the bladder is strongly associated with chronic irritation or inflammation, it is still unlikely due to the laboratory results and no strong association with radiation has been reported. The history of radiation exposure produced a suspicion of mesenchymal tumor origin. The reported incidence of post-irradiation sarcoma ranges from some few per thousand to nearly 1% . However, most cases have been seen in patients with breast cancer who received adjuvant radiation therapy, and the sites of sarcomas are usually soft tissue in origin. Even though her history indicated that the biopsy diagnosis was high-grade urothelial carcinoma, the diagnosis was reasonable, in our opinion, because of the much higher incidence of urothelial carcinomas, frequently found sarcomatoid components in high-grade urothelial carcinomas, and limited clinical information available. From gross pathological examination, the mass was obviously unlikely for carcinomas, as tumors at this large size usually present as a bulky mass, often with necrosis, and should not have a smooth surface. Therefore, suspicion of sarcomas or lymphomas should be raised.	4.125	0.949219	sec[2]/p[1]	en	0.999998	22074680	https://doi.org/10.1186/1752-1947-5-549	[ "urothelial", "carcinoma", "radiation", "carcinomas", "large", "urine", "even", "though", "unlikely", "suspicion" ]	[ { "code": "2C94.2", "title": "Urothelial carcinoma of bladder" }, { "code": "2C9Z", "title": "Malignant neoplasms of urinary tract, unspecified" }, { "code": "2F35", "title": "Benign neoplasm of urinary organs" }, { "code": "2C92.0", "title": "Urothelial carcinoma of ureter" }, { "code": "2C91.0", "title": "Urothelial carcinoma of renal pelvis" }, { "code": "2D41", "title": "Unspecified carcinoma of unspecified site" }, { "code": "2C3Y", "title": "Other specified malignant neoplasms of skin" }, { "code": "2E6Z", "title": "Carcinoma in situ of unspecified site" }, { "code": "2C25.5", "title": "Unspecified malignant epithelial neoplasm of bronchus or lung" }, { "code": "2C90.Y", "title": "Other specified malignant neoplasms of kidney, except renal pelvis" } ]	=== ICD-11 CODES FOUND === [2C94.2] Urothelial carcinoma of bladder Also known as: Urothelial carcinoma of bladder \| TCC - [transitional cell carcinoma] of bladder \| Non-papillary transitional cell carcinoma of the bladder [2C9Z] Malignant neoplasms of urinary tract, unspecified Also known as: Malignant neoplasms of urinary tract, unspecified \| malignant neoplasm of unspecified urinary organ without mention of type \| Transitional cell carcinoma of unspecified site \| Urothelial cancer of unspecified site [2F35] Benign neoplasm of urinary organs Definition: A non-metastasizing neoplasm that arises from the organs that comprise the urinary system. Representative examples include renal oncocytoma, bladder inverted papilloma, and urothelial papilloma. Also known as: Benign neoplasm of urinary organs \| Benign neoplasm of kidney \| renal benign neoplasm \| benign renal tumour \| benign tumour of kidney [2C92.0] Urothelial carcinoma of ureter Also known as: Urothelial carcinoma of ureter [2C91.0] Urothelial carcinoma of renal pelvis Also known as: Urothelial carcinoma of renal pelvis \| Transitional cell carcinoma of renal pelvis [2D41] Unspecified carcinoma of unspecified site Also known as: Unspecified carcinoma of unspecified site \| carcinoma of unspecified primary site \| carcinoma NOS \| Carcinoma in polyp of unspecified site \| Carcinoma with apocrine metaplasia of unspecified site [2C3Y] Other specified malignant neoplasms of skin Also known as: Other specified malignant neoplasms of skin \| Malignant neoplasm of eyelid NOS \| Malignant pilonidal cyst \| Radiotherapy-induced skin malignancy \| Cutaneous carcinoma [2E6Z] Carcinoma in situ of unspecified site Also known as: Carcinoma in situ of unspecified site \| carcinoma in situ of unspecified site \| carcinoma in situ NOS \| carcinoma in situ \| in situ neoplasm [2C25.5] Unspecified malignant epithelial neoplasm of bronchus or lung Also known as: Unspecified malignant epithelial neoplasm of bronchus or lung \| unspecified carcinoma of bronchus or lung \| Metastatic lung carcinoma [primary lung carcinoma spreading elsewhere] \| Metastatic carcinoma of lung [primary carcinoma of lung spreading elsewhere] \| Lung carcinoma [2C90.Y] Other specified malignant neoplasms of kidney, except renal pelvis Also known as: Other specified malignant neoplasms of kidney, except renal pelvis \| Congenital mesoblastic nephroma \| Nephroblastoma \| Wilms tumour of kidney \| Wilms tumour of unspecified site Includes: Nephroblastoma === GRAPH WALKS === --- Walk 1 --- [2C94.2] Urothelial carcinoma of bladder --PARENT--> [2C94] Malignant neoplasms of bladder Def: A primary or metastatic malignant neoplasm involving the bladder.... --EXCLUDES--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --- Walk 2 --- [2C94.2] Urothelial carcinoma of bladder --PARENT--> [2C94] Malignant neoplasms of bladder Def: A primary or metastatic malignant neoplasm involving the bladder.... --CHILD--> [2C94.1] Squamous cell carcinoma of urinary bladder Def: A squamous cell carcinoma of the bladder arising from metaplastic epithelium. It represents less than 10% of bladder carcinomas. The exception is the Middle East along the Nile Valley, where it repres... --- Walk 3 --- [2C9Z] Malignant neoplasms of urinary tract, unspecified --PARENT--> [?] Malignant neoplasms of urinary tract Def: A primary or metastatic malignant tumour involving the urinary system. Common tumour types include carcinomas, lymphomas, and sarcomas.... --CHILD--> [2C91] Malignant neoplasms of renal pelvis Def: Abnormal malignant growth of the cells within the renal pelvis.... --- Walk 4 --- [2C9Z] Malignant neoplasms of urinary tract, unspecified --PARENT--> [?] Malignant neoplasms of urinary tract Def: A primary or metastatic malignant tumour involving the urinary system. Common tumour types include carcinomas, lymphomas, and sarcomas.... --EXCLUDES--> [?] Malignant mesenchymal neoplasms Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn... --- Walk 5 --- [2F35] Benign neoplasm of urinary organs Def: A non-metastasizing neoplasm that arises from the organs that comprise the urinary system. Representative examples include renal oncocytoma, bladder inverted papilloma, and urothelial papilloma.... --PARENT--> [?] Benign neoplasms except of mesenchymal origin --CHILD--> [2E91] Benign neoplasm of major salivary glands --- Walk 6 --- [2F35] Benign neoplasm of urinary organs Def: A non-metastasizing neoplasm that arises from the organs that comprise the urinary system. Representative examples include renal oncocytoma, bladder inverted papilloma, and urothelial papilloma.... --PARENT--> [?] Benign neoplasms except of mesenchymal origin --CHILD--> [2E90] Benign neoplasm of lip, oral cavity or pharynx	[ "[2C94.2] Urothelial carcinoma of bladder\n --PARENT--> [2C94] Malignant neoplasms of bladder\n Def: A primary or metastatic malignant neoplasm involving the bladder....\n --EXCLUDES--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...", "[2C94.2] Urothelial carcinoma of bladder\n --PARENT--> [2C94] Malignant neoplasms of bladder\n Def: A primary or metastatic malignant neoplasm involving the bladder....\n --CHILD--> [2C94.1] Squamous cell carcinoma of urinary bladder\n Def: A squamous cell carcinoma of the bladder arising from metaplastic epithelium. It represents less than 10% of bladder carcinomas. The exception is the Middle East along the Nile Valley, where it repres...", "[2C9Z] Malignant neoplasms of urinary tract, unspecified\n --PARENT--> [?] Malignant neoplasms of urinary tract\n Def: A primary or metastatic malignant tumour involving the urinary system. Common tumour types include carcinomas, lymphomas, and sarcomas....\n --CHILD--> [2C91] Malignant neoplasms of renal pelvis\n Def: Abnormal malignant growth of the cells within the renal pelvis....", "[2C9Z] Malignant neoplasms of urinary tract, unspecified\n --PARENT--> [?] Malignant neoplasms of urinary tract\n Def: A primary or metastatic malignant tumour involving the urinary system. Common tumour types include carcinomas, lymphomas, and sarcomas....\n --EXCLUDES--> [?] Malignant mesenchymal neoplasms\n Def: A usually aggressive malignant mesenchymal cell tumour most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The progn...", "[2F35] Benign neoplasm of urinary organs\n Def: A non-metastasizing neoplasm that arises from the organs that comprise the urinary system. Representative examples include renal oncocytoma, bladder inverted papilloma, and urothelial papilloma....\n --PARENT--> [?] Benign neoplasms except of mesenchymal origin\n --CHILD--> [2E91] Benign neoplasm of major salivary glands", "[2F35] Benign neoplasm of urinary organs\n Def: A non-metastasizing neoplasm that arises from the organs that comprise the urinary system. Representative examples include renal oncocytoma, bladder inverted papilloma, and urothelial papilloma....\n --PARENT--> [?] Benign neoplasms except of mesenchymal origin\n --CHILD--> [2E90] Benign neoplasm of lip, oral cavity or pharynx" ]	2C94.2	Urothelial carcinoma of bladder	[ { "from_icd11": "2C9Z", "icd10_code": "C689", "icd10_title": "Malignant neoplasm of urinary organ, unspecified" }, { "from_icd11": "2C9Z", "icd10_code": "C64-C68", "icd10_title": "" }, { "from_icd11": "2C9Z", "icd10_code": "C68", "icd10_title": "Malignant neoplasm of other and unspecified urinary organs" }, { "from_icd11": "2F35", "icd10_code": "D3002", "icd10_title": "Benign neoplasm of left kidney" }, { "from_icd11": "2F35", "icd10_code": "D3000", "icd10_title": "Benign neoplasm of unspecified kidney" }, { "from_icd11": "2F35", "icd10_code": "D3001", "icd10_title": "Benign neoplasm of right kidney" }, { "from_icd11": "2F35", "icd10_code": "D303", "icd10_title": "Benign neoplasm of bladder" }, { "from_icd11": "2F35", "icd10_code": "D30", "icd10_title": "Benign neoplasm of urinary organs" }, { "from_icd11": "2F35", "icd10_code": "D300", "icd10_title": "Benign neoplasm of kidney" }, { "from_icd11": "2F35", "icd10_code": "D301", "icd10_title": "Benign neoplasm of renal pelvis" }, { "from_icd11": "2F35", "icd10_code": "D302", "icd10_title": "Benign neoplasm of ureter" }, { "from_icd11": "2F35", "icd10_code": "D304", "icd10_title": "Benign neoplasm of urethra" }, { "from_icd11": "2F35", "icd10_code": "D307", "icd10_title": "" }, { "from_icd11": "2F35", "icd10_code": "D309", "icd10_title": "Benign neoplasm of urinary organ, unspecified" }, { "from_icd11": "2E6Z", "icd10_code": "D098", "icd10_title": "Carcinoma in situ of other specified sites" } ]	C689	Malignant neoplasm of urinary organ, unspecified
A 58-year-old male presented with asthenia, abdominal pain and slight hepatosplenomegaly. The blood count was abnormal with anemia of Hb 10.9 g/dl and a platelet count of 41×10 3 /mm 3 . The white blood cell count was 10.8×10 3 /mm 3 with 38% lymphocytes, 6% monocytes, 4% myelocytes and metamyelocytes, and 58% small lymphoblasts. Immunophenotyping of bone marrow disclosed B-lineage lymphoblasts (CD34 + , CD19 + , CD10 + , MPO − , CD79a + , HLA-DR + , Tdt + , CD22 + , and CD24 + ). Karyotyping performed on the marrow aspirate revealed 49,XY,+X,+2,+4,−9,−11,+19,add(19)(q13),+20,−22,+mar in 24 of 25 metaphases examined. BCR-ABL and MLL rearrangements were not detected by standard fluorescence in situ hybridization (FISH). While reverse transcriptase polymerase chain reaction (RT-PCR) analyses for BCR-ABL rearrangements were negative, we found a new BCR-JAK2 transcript. The patient was diagnosed with ALL and started a standard high-risk ALL protocol. Hematologic, cytogenetic, and complete molecular remission (CMR) was achieved after five weeks, and the treatment proceeded through four standard consolidation cycles followed by an autologous peripheral blood stem cell transplant (SCT) with cyclophosphamide and total body irradiation (12 Gy). Low-dose interferon alpha was administered for five months as maintenance antileukemia therapy. More than six years later, the patient remains in complete remission.	4.09375	0.973633	sec[1]/sec[1]/p[0]	en	0.999996	22384256	https://doi.org/10.1371/journal.pone.0032451	[ "blood", "count", "standard", "cell", "lymphoblasts", "marrow", "rearrangements", "complete", "remission", "five" ]	[ { "code": "3C0Z", "title": "Diseases of the blood or blood-forming organs, unspecified" }, { "code": "MF50.4Z", "title": "Haematuria, unspecified" }, { "code": "MA12.1", "title": "Finding of cocaine in blood" }, { "code": "MA12.4", "title": "Finding of steroid agent in blood" }, { "code": "MA12.2", "title": "Finding of hallucinogen in blood" }, { "code": "3B63.1Z", "title": "Acquired thrombocytosis, unspecified" }, { "code": "3B64.Z", "title": "Thrombocytopenia, unspecified" }, { "code": "4B0Z", "title": "Immune system disorders involving white cell lineages, unspecified" }, { "code": "4B03.Z", "title": "Eosinophilia, unspecified" }, { "code": "4B00.1Z", "title": "Neutrophilia, unspecified" } ]	=== ICD-11 CODES FOUND === [3C0Z] Diseases of the blood or blood-forming organs, unspecified Also known as: Diseases of the blood or blood-forming organs, unspecified \| Blood, lymph or spleen disease \| blood condition NOS \| blood disorder NOS \| bone marrow disease NOS [MF50.4Z] Haematuria, unspecified Also known as: Haematuria, unspecified \| Haematuria \| blood in urine \| urinary blood \| haematuria NOS [MA12.1] Finding of cocaine in blood Also known as: Finding of cocaine in blood \| cocaine in blood [MA12.4] Finding of steroid agent in blood Also known as: Finding of steroid agent in blood \| steroid in blood [MA12.2] Finding of hallucinogen in blood Also known as: Finding of hallucinogen in blood \| hallucinogen in blood [3B63.1Z] Acquired thrombocytosis, unspecified Also known as: Acquired thrombocytosis, unspecified \| Acquired thrombocytosis \| Idiopathic haemorrhagic thrombocythaemia \| Essential thrombocythaemia \| primary haemorrhagic thrombocythaemia [3B64.Z] Thrombocytopenia, unspecified Also known as: Thrombocytopenia, unspecified \| Thrombocytopenia \| low platelet count \| low platelets \| decreased platelets [4B0Z] Immune system disorders involving white cell lineages, unspecified Also known as: Immune system disorders involving white cell lineages, unspecified [4B03.Z] Eosinophilia, unspecified Also known as: Eosinophilia, unspecified \| Eosinophilia \| Disorders with increased eosinophil counts \| Idiopathic hypereosinophilic syndrome [4B00.1Z] Neutrophilia, unspecified Also known as: Neutrophilia, unspecified \| Neutrophilia \| Disorders with increased neutrophil counts === GRAPH WALKS === --- Walk 1 --- [3C0Z] Diseases of the blood or blood-forming organs, unspecified --PARENT--> [03] Diseases of the blood or blood-forming organs Def: This chapter includes diseases of the blood as well as diseases of blood forming organs.... --PARENT--> [?] ICD-11 for Mortality and Morbidity Statistics --- Walk 2 --- [3C0Z] Diseases of the blood or blood-forming organs, unspecified --PARENT--> [03] Diseases of the blood or blood-forming organs Def: This chapter includes diseases of the blood as well as diseases of blood forming organs.... --CHILD--> [?] Anaemias or other erythrocyte disorders --- Walk 3 --- [MF50.4Z] Haematuria, unspecified --PARENT--> [MF50.4] Haematuria Def: Hematuria means presence of blood or red blood cells (RBCs) in the urine. There are two types of hematuria: gross hematuria (when one can see the blood in the urine) and microscopic hematuria (when th... --CHILD--> [MF50.41] Microscopic haematuria --- Walk 4 --- [MF50.4Z] Haematuria, unspecified --PARENT--> [MF50.4] Haematuria Def: Hematuria means presence of blood or red blood cells (RBCs) in the urine. There are two types of hematuria: gross hematuria (when one can see the blood in the urine) and microscopic hematuria (when th... --CHILD--> [MF50.4Z] Haematuria, unspecified --- Walk 5 --- [MA12.1] Finding of cocaine in blood --PARENT--> [MA12] Clinical findings of drugs, medicaments and biological substances in blood, blood-forming organs, or the immune system --CHILD--> [MA12.2] Finding of hallucinogen in blood --- Walk 6 --- [MA12.1] Finding of cocaine in blood --PARENT--> [MA12] Clinical findings of drugs, medicaments and biological substances in blood, blood-forming organs, or the immune system --CHILD--> [MA12.1] Finding of cocaine in blood	[ "[3C0Z] Diseases of the blood or blood-forming organs, unspecified\n --PARENT--> [03] Diseases of the blood or blood-forming organs\n Def: This chapter includes diseases of the blood as well as diseases of blood forming organs....\n --PARENT--> [?] ICD-11 for Mortality and Morbidity Statistics", "[3C0Z] Diseases of the blood or blood-forming organs, unspecified\n --PARENT--> [03] Diseases of the blood or blood-forming organs\n Def: This chapter includes diseases of the blood as well as diseases of blood forming organs....\n --CHILD--> [?] Anaemias or other erythrocyte disorders", "[MF50.4Z] Haematuria, unspecified\n --PARENT--> [MF50.4] Haematuria\n Def: Hematuria means presence of blood or red blood cells (RBCs) in the urine. There are two types of hematuria: gross hematuria (when one can see the blood in the urine) and microscopic hematuria (when th...\n --CHILD--> [MF50.41] Microscopic haematuria", "[MF50.4Z] Haematuria, unspecified\n --PARENT--> [MF50.4] Haematuria\n Def: Hematuria means presence of blood or red blood cells (RBCs) in the urine. There are two types of hematuria: gross hematuria (when one can see the blood in the urine) and microscopic hematuria (when th...\n --CHILD--> [MF50.4Z] Haematuria, unspecified", "[MA12.1] Finding of cocaine in blood\n --PARENT--> [MA12] Clinical findings of drugs, medicaments and biological substances in blood, blood-forming organs, or the immune system\n --CHILD--> [MA12.2] Finding of hallucinogen in blood", "[MA12.1] Finding of cocaine in blood\n --PARENT--> [MA12] Clinical findings of drugs, medicaments and biological substances in blood, blood-forming organs, or the immune system\n --CHILD--> [MA12.1] Finding of cocaine in blood" ]	3C0Z	Diseases of the blood or blood-forming organs, unspecified	[ { "from_icd11": "3C0Z", "icd10_code": "D75A", "icd10_title": "Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia" }, { "from_icd11": "3C0Z", "icd10_code": "D7581", "icd10_title": "Myelofibrosis" }, { "from_icd11": "3C0Z", "icd10_code": "D7582", "icd10_title": "Heparin induced thrombocytopenia (HIT)" }, { "from_icd11": "3C0Z", "icd10_code": "D7589", "icd10_title": "Other specified diseases of blood and blood-forming organs" }, { "from_icd11": "3C0Z", "icd10_code": "D759", "icd10_title": "Disease of blood and blood-forming organs, unspecified" }, { "from_icd11": "3C0Z", "icd10_code": "D763", "icd10_title": "Other histiocytosis syndromes" }, { "from_icd11": "3C0Z", "icd10_code": "Q899", "icd10_title": "Congenital malformation, unspecified" }, { "from_icd11": "3C0Z", "icd10_code": "III", "icd10_title": "" }, { "from_icd11": "3C0Z", "icd10_code": "D70-D77", "icd10_title": "" }, { "from_icd11": "3C0Z", "icd10_code": "D75", "icd10_title": "Other and unspecified diseases of blood and blood-forming organs" }, { "from_icd11": "3C0Z", "icd10_code": "D77", "icd10_title": "Other disorders of blood and blood-forming organs in diseases classified elsewhere" }, { "from_icd11": "3C0Z", "icd10_code": "D758", "icd10_title": "Other specified diseases of blood and blood-forming organs" }, { "from_icd11": "3C0Z", "icd10_code": "D76", "icd10_title": "Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue" }, { "from_icd11": "MF50.4Z", "icd10_code": "R310", "icd10_title": "Gross hematuria" }, { "from_icd11": "MF50.4Z", "icd10_code": "R312", "icd10_title": "Other microscopic hematuria" } ]	D75A	Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia

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